Preparation containing flumetofen and application thereof

Abstract

The invention belongs to the field of insecticides, and particularly discloses a flumetofen-containing preparation and application thereof. The preparation can be flumetofen-containing powder, oil dispersible powder, soluble tablets, soluble sol, oil, spreading oil, dispersible liquid, ointment, oil emulsion, fat, seed treatment dry powder, seed treatment dispersible powder, seed treatment liquid, seed treatment emulsion or seed treatment suspending agent, and the preparation can be flumetofen-containing powder, oil dispersible powder, soluble tablets, soluble sol, oil, spreading oil, dispersible liquid, ointment, oil emulsion, fat, seed treatment dry powder, seed treatment dispersible powder, seed treatment emulsion or seed treatment suspending agent. Wherein the mass of the flumetofen accounts for 2-70% of that of the preparation. According to the invention, by matching an auxiliary agent system which is better than the active component of the flumetofen, the permeation speed and permeation amount of the liquid medicine to a target are increased, the wetting effect and deposition amount of the liquid medicine to the target are enhanced, the evaporation amount is reduced, and the actual effective utilization rate of the active component is improved, so that the purposes of enhancing the use effect, reducing the use dosage and reducing the cost are achieved. And the generation of resistance is delayed, and the pollution to the environment is reduced, so that the shelf life of the compound is prolonged, and the compound can better serve agricultural industrialization.

Description

Technical Field

[0001] The present invention belongs to the field of pesticides, and specifically discloses a preparation containing flubenzolate and its application. Background Art

[0002] Pesticides play an obvious role in controlling agricultural and forestry pests or urban sanitation pests. According to the statistics of international companies, it currently takes about 200 million euros and about 12 years to screen out one commercialized compound from 160,000 synthesized compounds. Thus, it can be seen the difficulty of industrializing self-developed compounds. However, in the actual application process of agricultural production, when a new compound emerges, the most likely problem in pest control is the emergence of pest resistance. The faster the resistance emerges, the shorter its life cycle. For the preparation application of a compound, maximizing its development and formulation is an important and meaningful task. Therefore, improving the application dosage form range of new compounds and their rational use are the key factors for extending the life cycle of developed compounds. The biphenyl compounds disclosed in Chinese invention patent CN 105541682A have excellent acaricidal control effects and broad market application prospects. This compound has obtained the common name flubenzolate, and further continuous development is required to achieve unexpected effects. Summary of the Invention

[0003] The purpose of the present invention is to broaden the application of the compound flubenzolate, specifically to determine a better auxiliary agent system that matches the active ingredient of flubenzolate. This auxiliary agent system can make the dosage form prepared from flubenzolate more convenient and broaden its application field to seed treatment applications, in order to achieve the purpose of extending the shelf life of flubenzolate and the application time of the compound.

[0004] To achieve the purpose of the present invention, the inventors, based on the action target and application method of flubenzolate, studied the structure-activity relationship between different auxiliary agent systems and the active ingredient, and combined with the actual measurement and comparison results, compared the situations of the liquid medicines of different preparation systems when preparing various dosage forms, and carried out a large amount of research work. The research found that: on the one hand, a better auxiliary agent system can meet the requirement of preparing flubenzolate into an applicable preparation; on the other hand, when the key functional auxiliary agent is added, a preparation with a low shedding rate and good seed coating performance can be obtained when preparing a seed treatment agent.

[0005] The technical solution of the present invention is as follows:

[0006] A preparation containing flubenzolate, which is a powder containing flubenzolate, an oil-dispersed powder, a soluble tablet, a sol, an oil, a film-forming oil, a dispersible concentrate, an ointment, an oil emulsion, a fat, a seed treatment dry powder, a seed treatment dispersible powder, a seed treatment liquid, a seed treatment emulsion or a seed treatment suspension; wherein, the mass of flubenzolate accounts for 2-70% of the preparation.

[0007] In the said preparation, by mass percentage, flubenzimine is 2 - 70%, organic solvent is 0 - 15%, auxiliary agent is 8 - 50%, and carrier is 10 - 90%.

[0008] In the said powder, by weight percentage, it contains 2 - 70% flubenzimine, 8 - 40% surfactant, and the balance is carrier;

[0009] In the oil - dispersed powder, by weight percentage, it contains 2 - 70% flubenzimine, 8 - 40% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0010] In the soluble tablet, by weight percentage, it contains 2 - 70% flubenzimine, 8 - 40% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0011] In the soluble concentrate, by weight percentage, it contains 2 - 70% flubenzimine, 8 - 40% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0012] In the oil preparation, by weight percentage, it contains 2 - 70% flubenzimine, 2 - 20% functional auxiliary agent, and the balance is organic solvent;

[0013] In the film - spreading oil preparation, by weight percentage, it contains 2 - 70% flubenzimine, 2 - 20% functional auxiliary agent, and the balance is organic solvent.

[0014] In the dispersible concentrate, by weight percentage, it contains 2 - 70% flubenzimine, 8 - 40% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0015] In the paste preparation, by weight percentage, it contains 2 - 70% flubenzimine, 6 - 30% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0016] In the oil emulsion, by weight percentage, it contains 2 - 70% flubenzimine, 8 - 40% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0017] In the fat preparation, by weight percentage, it contains 2 - 70% flubenzimine, 6 - 30% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0018] In the paste preparation, by weight percentage, it contains 2 - 70% flubenzimine, 6 - 30% surfactant, 1 - 15% organic solvent, and the balance is carrier;

[0019] In the dry powder for seed treatment, by weight percentage, it contains 2 - 70% flubenzimine, 6 - 30% surfactant, 2 - 20% functional auxiliary agent, and the balance is carrier;

[0020] In the dispersible powder for seed treatment, by weight percentage, it contains 2 - 70% flubenzimine, 6 - 30% surfactant, 2 - 20% functional auxiliary agent, and the balance is carrier;

[0021] The seed treatment liquid formulation contains, by weight percentage, 2 - 70% of flubenzolate, 1 - 15% of organic solvent, 6 - 30% of surfactant, 2 - 20% of functional auxiliary agent, and the balance of water;

[0022] The seed treatment emulsion contains, by weight percentage, 2 - 70% of flubenzolate, 1 - 15% of organic solvent, 6 - 30% of surfactant, 2 - 20% of functional auxiliary agent, and the balance of water;

[0023] The seed treatment suspension contains, by weight percentage, 2 - 70% of flubenzolate, 6 - 20% of surfactant, 3 - 30% of functional auxiliary agent, and water to make up the balance.

[0024] The carrier is one or more of water, light mineral oil, paraffin, kerosene, clay, diatomite, bentonite, kaolin, attapulgite, magnesium aluminosilicate, activated clay, silica white, light calcium carbonate, pottery clay, ammonium sulfate, montmorillonite.

[0025] The organic solvent is one or more of aromatic hydrocarbons, chlorinated aromatic hydrocarbons, aliphatic hydrocarbons, chlorinated aliphatic hydrocarbons, alcohols and their ethers and esters, ketone compounds, vegetable oils and methyl cellulose.

[0026] The organic solvent is one or more of methanol, ethanol, isopropanol, butanol, ethylene glycol, ethylene glycol methyl ether, propylene glycol, glycerol, sorbitol, benzyl alcohol, furfuryl alcohol, cyclohexanol, acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone, N - methyl - pyrrolidone, N,N - dimethyl decanamide, N,N - dimethylacetamide, triethyl phosphate, tributyl phosphate, methyl oleate, dimethylformamide, dimethyl sulfoxide, methylated soybean oil, Armid DM10, Armid FMPC, Rhodiasolv Green SV - 92, Rhodiasolv Green SV - 33, Rhodiasolv Green 25, solvent oil S - 150, solvent oil S - 200.

[0027] The surfactant is one or more of fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ether, acid alcohol ester and its polyoxyethylene ether, fatty amide and its polyoxyethylene ether, alkanolamide and its polyoxyethylene ether, polyoxyethylene - polyoxypropylene block copolymer, sodium alkyl naphthalene sulfonate fatty alcohol polyoxyethylene ether, sorbitan fatty acid ester polyoxyethylene ether.

[0028] The surfactant is emulsifier SK-50EC, emulsifier SK-51EC, emulsifier 1601, emulsifier 0201B, emulsifier 0203B, emulsifier 500#, emulsifier 600#, emulsifier 700#, emulsifier NP-10, dispersant SK-33L, dispersant SK-33H, emulsifier OX-8686, emulsifier OX-2681, emulsifier 2201, emulsifier OX-690, dispersant DURAMAX TM D-205, dispersant DURAMAX TM D-305, dispersant DURAMAX TM W600, dispersant DURAMAX TM D800, emulsifier SK-5208T, emulsifier SK-5215T, emulsifier YUS-D625, emulsifier YUS-135B, emulsifier YUS-EC2200, emulsifier SK-5026ECH, emulsifier YUS-110, emulsifier SK-5212T, emulsifier YUS-A41B, emulsifier Emulson AG / 18C, Greenmul 5100, TANEMULSPS29, D865, emulsifier YUS-2010CX, emulsifier S-80, emulsifier T-20, emulsifier SK-5935, dispersant YUS-D3020, dispersant SK-20TX, dispersant SD811, wetting agent SP-3266E, dispersant SP-2728, dispersant SP-SC29, dispersant SP-28F, dispersant SP-2750, dispersant TENSIOFIX SC, TENSIOFIX96DB10, wetting agent TENSIOFIX BCZ, dispersant D425, dispersant YUS-FS1, dispersant YUS-FS3000, dispersant YUS-FS3300, dispersant YUS-FS7PG, dispersant YUS-TXC, dispersant SP-27001, Greensperse BE02, Greensperse BE23, TANEMUL DA2883, TANEMUL DA2880, TANEMUL DA260, Atlox 4913, XN-45S, emulsifier 507, dispersant SK-33SC, dispersant SK-541, dispersant SK-551, dispersant SK-94S7, dispersant SK-551G, emulsifier SK-5218CP, emulsifier SK-5220T, dispersant SK-92FS1, emulsifier YUS-CP120, triphenylvinylphenol polyoxyethylene(n 20)Triethanolamine salt of ether phosphoric acid, synergist SK-41G, synergist SK-41CN, synergist SK-41A, ULTRASURF OD21, ULTRASURF OD23, emulsifier YUS-OD1200, emulsifier AEO-3, dispersant SP-OF3468, dispersant SP-OF3472, G-VO / 02N, Greenmul EF68, Greenmul EF46, Atlox 4912, Atlox 4914, GR7M, emulsifier OX-635, emulsifier OX-622, emulsifier OX-653, emulsifier OX-667, emulsifier AEO-9, emulsifier T-85, dispersant YUS-5050PB, dispersant YUS-EP70G, dispersant YUS-WG5, SP-4302 (moisturizing synergist), dispersant VE / 10, dispersant OE / 02, dispersant OE / 03, dispersant OE / 08, dispersant OE / 09, dispersant OE150, dispersant Emulson CO40, dispersant Emulson AG / 1100, ULTRASURF O / 23, sodium salt of alkylnaphthalene sulfonic acid condensate, sodium salt of methylnaphthalene sulfonate formaldehyde condensate, polycarboxylate dispersant GY-D800, polycarboxylate dispersant GY-D04, polycarboxylate dispersant GY-D02, sodium salt of naphthalene sulfonate formaldehyde condensate, sodium salt of naphthol sulfonic acid formaldehyde condensate, sodium methylene naphthalene sulfonate, sodium oleic acid methylaminoethyl sulfonate, dispersant SP-SC3, Darun dispersant D909S, alkylnaphthalene sulfonate formaldehyde condensate (NNO), dispersant YUS-NV1420, dispersant YUS-WG4, dispersant YUS-WP1, dispersant YUS-CH7000, emulsifier PICO-LOE, dispersant PICO-CS300M, dispersant PICO-SF3, dispersant PICO-SWP1, dispersant PICO-SF1, dispersant GeroponUltrasperse, dispersant GeroponExtra, dispersant Soprophor SC, dispersant Geropon DA1349, dispersant TENSIOFIX LX SPECIAL, dispersant TENSIOFIX DB08, dispersant Tensiofix AMS303, dispersant Tensiofix XA265, dispersant Tensiofix EW70, dispersant Tensiofix 96DB10, dispersant SK-24R, dispersant SP-SC3275, dispersant SK-25CH, dispersant SK-34SC, dispersant YUS-CH1100, dispersant Supragil MNS / 90, dispersant Soprophor FD, dispersant Soprophor TSP / 461, dispersant SoprophorOne or more of 796 / P, dispersant SD819, dispersant Morwet D-400, dispersant Morwet D-360, dispersant Morwet D-390, dispersant Geronol ODessa 01, dispersant Geronol ODessa 05, dispersant YUS-D935, dispersant TANEMUL DA266, dispersant TANEMUL AG281, octylphenol polyoxyethylene ether sulfate, wetting agent Morwet EFW, wetting agent Igepal BC / 10, wetting agent GEROPONL-WET / P, wetting agent Supragil WP, wetting agent Supragil GN, wetting agent Rhodasurf 860 / p, emulsifier YUS-A51G, wetting agent YUS-LXC, wetting agent YUS-SXC, sodium isopropylnaphthalenesulfonate, sodium alkyl alcohol polyoxyethylene ether sulfate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkyl sulfosuccinate, sodium lauryl alcohol polyoxyethylene ether sulfonate, sodium dodecylbenzenesulfonate, sodium dodecyl sulfate, calcium dodecylbenzenesulfonate, calcium lignosulfonate, alkamido taurate.

[0029] The functional adjuvant is one or more of SP-SC3275, polyvinyl alcohol, chitosan, and warning color.

[0030] Apply the said preparation at 10 - 1000 g active ingredient / hectare to the pests to be controlled or the medium on which they grow.

[0031] The functional adjuvant is one or more of SP-SC3275, polyvinyl alcohol, chitosan, and warning color. The warning color is applied during seed treatment and may include dyes, pigments (including color powder and color paste), etc.

[0032] During the preparation process of the above various dosage forms, when bubbles appear in the system, an antifoaming agent can be used to eliminate the bubbles. The antifoaming agent can be one or more of SAG1522, silicone, C8 - 10 fatty alcohols, phosphate esters, C10 - 20 saturated fatty acids (such as capric acid), and amides or others.

[0033] Substances with anti-corrosion functions can also be added to the system. The preservative can be one or more of sodium benzoate, Kathon (2 - methyl - 4 - isothiazolin - 3 - one and (B) 5 - chloro - 2 - methyl - 4 - isothiazolin - 3 - one), potassium sorbate, sodium dehydroacetate, or others.

[0034] Application of a preparation containing flubenzolate, the application of the said preparation in controlling pests and / or mites.

[0035] A preparation containing flubenzolate, and the preparation is applied to pests to be controlled or the medium for their growth at a rate of 10 to 1000 grams of active ingredient per hectare.

[0036] Advantages of the present invention

[0037] In the present invention, flubenzolate is used as the active ingredient to develop a suitable dosage form, and with a suitable adjuvant system, its application performance is good. By matching with an adjuvant system that is better for the flubenzolate active component, the penetration speed and penetration amount of the liquid medicine to the target are increased, the wetting effect of the liquid medicine and the deposition amount on the target are enhanced, the evaporation amount is reduced, the actual effective utilization rate of the active component is improved, so as to enhance its use effect, reduce the dosage, delay the generation of its resistance, reduce the environmental pollution, and further extend the shelf life of the compound, making it better serve the agricultural industrialization.

[0038] The present invention also develops another use of flubenzolate for controlling underground pests and applying it in seed treatment. It is used for coating crops such as rice, wheat, soybeans, peanuts, corn, tobacco, vegetables, and potatoes, and has excellent control effects on pests such as Spodoptera exigua, Plutella xylostella, Mythimna separata, and Chilo suppressalis. The obtained seed treatment agent has significant advantages in the application performance of the formulation technology, and its safety is excellent. Especially in terms of the shedding rate of seed treatment, there is a great improvement and significant enhancement. Detailed implementation manners

[0039] The following specific examples are used to further illustrate the present invention in detail, but the present invention is by no means limited to these examples. Percentages and parts in the formula are by weight. The active ingredient flubenzolate (content 95%) is metered and added after converting to 100%. Flubenzolate is a biphenyl compound disclosed in Chinese invention patent CN 105541682A, and its structural formula is as follows:

[0040]

[0041] Other raw materials are all commercially available products.

[0042] Formulation examples of the preparation

[0043] Example 1, 70% flubenzolate powder

[0044] According to the formula requirements, 70% of flubenzolate, 5% of calcium lignosulfonate, 3% of Morwet D-390, 2% of SPSC3275, 5% of silica white, and the balance of light calcium carbonate is made up to 100%, then 70% flubenzolate wettable powder can be obtained.

[0045] Example 2, 50% flubenzolate oil-dispersed powder

[0046] According to the formulation requirements, 50% of flubenzimine, 5% of solvent oil S-150, 10% of lignosulfonate, 53% of YUS-WG, 15% of SPSC3275, 5% of silica white, and the balance of light calcium carbonate is added up to 100%, then 50% flubenzimine wettable powder can be obtained.

[0047] Example 3, 40% flubenzimine film-forming oil agent

[0048] According to the formulation requirements, 40% of flubenzimine, 20% of SPSC3275, and 60% of solvent oil S-150 are stirred and mixed evenly, then 40% flubenzimine film-forming oil agent can be obtained.

[0049] Example 4, 15% flubenzimine dispersible concentrate

[0050] According to the formulation requirements, 15% of flubenzimine, 20% of methyl oleate, 10% of Tensiofix AMS303, and 10% of DURAMAXTM D800 are stirred and mixed evenly, then 15% flubenzimine dispersible concentrate can be obtained.

[0051] Example 5, 60% flubenzimine seed treatment dry powder

[0052] According to the formulation requirements, 60% of flubenzimine, 7% of sodium dodecylbenzenesulfonate, 0.6% of rose spirit, 2% of silica white, and the balance of light calcium carbonate is added up to 100%. After air-flow pulverization, 60% flubenzimine seed treatment dry powder can be obtained.

[0053] Example 5-1, 60% flubenzimine seed treatment dry powder

[0054] According to the formulation requirements, 60% of flubenzimine, 7% of sodium dodecylbenzenesulfonate, 0.6% of rose spirit, 4% of SPSC3275, 2% of silica white, and the balance of light calcium carbonate is added up to 100%. After air-flow pulverization, 60% flubenzimine seed treatment dry powder can be obtained.

[0055] Example 6, 45% flubenzimine seed treatment dispersible powder

[0056] According to the formulation requirements, 45% of flubenzimine, 2% of Morwet EFW, 4% of dispersant YUS-CH7000, 4% of sodium dodecyl sulfate, 0.1% of rose spirit, and bentonite is added up to 100%. They are mixed and pulverized, then 45% flubenzimine seed treatment dispersible powder can be obtained.

[0057] Example 6-1, 45% flubenzimine seed treatment dispersible powder

[0058] According to the formulation requirements, add 45% of flubenzolate, 2% of Morwet EFW, 4% of dispersant YUS-CH7000, 12% of SPSC3275, 4% of sodium dodecyl sulfate, 0.1% of rhodamine, and make up to 100% with bentonite, then mix and pulverize to obtain 45% flubenzolate seed treatment dispersible powder.

[0059] Example 7, 15% flubenzolate seed treatment liquid

[0060] According to the formulation requirements, add 15% of flubenzolate, 5% of GY-D800, 6% of YUS-EC2200, 0.1% of rhodamine, and make up with solvent oil 200# to obtain 15% flubenzolate seed treatment liquid.

[0061] Example 7-1, 15% flubenzolate seed treatment liquid

[0062] According to the formulation requirements, add 15% of flubenzolate, 5% of GY-D800, 6% of YUS-EC2200, 0.1% of rhodamine, 2% of SPSC3275, and make up with solvent oil 200# to obtain 15% flubenzolate seed treatment liquid.

[0063] Example 8, 10% flubenzolate seed treatment emulsion

[0064] According to the formulation requirements, add 10% of flubenzolate, 5% of emulsifier 1601, 6% of TENSIOFIX 96DB10, 0.1% of rhodamine, 10% of solvent oil 200#, 0.1% of DMF, and make up to 100% with water to obtain 10% flubenzolate seed treatment emulsion.

[0065] Example 8-1, 10% flubenzolate seed treatment emulsion

[0066] According to the formulation requirements, add 10% of flubenzolate, 5% of emulsifier 1601, 6% of TENSIOFIX 96DB10, 0.1% of rhodamine, 10% of solvent oil 200#, 0.1% of DMF, 6% of SPSC3275, and make up to 100% with water to obtain 10% flubenzolate seed treatment emulsion.

[0067] Example 9, 30% flubenzolate seed treatment suspension

[0068] According to the formulation requirements, add 30% of flubenzolate, 6% of SK-92FS1, 6% of Atlox 4912, 15% of RED13, 0.5% of white carbon black, and make up to 100% with water. Subject the materials to high-shear treatment and pulverization, then transfer to a sand mill for sanding. Use a particle size distribution analyzer to detect the particle size of the sanded materials. After the particle size reaches the standard, filter to obtain 30% flubenzolate seed treatment suspension.

[0069] Example 9-1, 30% flubenzimine seed treatment suspension concentrate

[0070] According to the formulation requirements, 30% flubenzimine, 6% SK-92FS1, 6% Atlox 4912, 15% RED131, 0.5% silica white, 8% SPSC3275, and water are added up to 100%. The materials are subjected to high-shear treatment and pulverization, then transferred to a sand mill for sanding. The particle size of the sanded materials is detected by a particle size distribution analyzer. After the particle size reaches the standard, filtration is carried out to obtain 30% flubenzimine seed treatment suspension concentrate.

[0071] Example 10, 15% flubenzimine seed treatment suspension concentrate

[0072] According to the formulation requirements, 15% flubenzimine, 6% TENSIOFIX DB08, 6% Tensiofix AMS303, 7% RED131, 1% silica white, and water are added up to 100%. The materials are subjected to high-shear treatment and pulverization, then transferred to a sand mill for sanding. The particle size of the sanded materials is detected by a particle size distribution analyzer. After the particle size reaches the standard, filtration is carried out to obtain 15% flubenzimine seed treatment suspension concentrate.

[0073] Example 10-1, 15% flubenzimine seed treatment suspension concentrate

[0074] According to the formulation requirements, 15% flubenzimine, 6% TENSIOFIX DB08, 6% Tensiofix AMS303, 7% RED131, 8% SPSC3275, 1% silica white, and water are added up to 100%. The materials are subjected to high-shear treatment and pulverization, then transferred to a sand mill for sanding. The particle size of the sanded materials is detected by a particle size distribution analyzer. After the particle size reaches the standard, filtration is carried out to obtain 15% flubenzimine seed treatment suspension concentrate.

[0075] Determination of application performance:

[0076] The preparations in the above examples are used to coat corn seeds, and the following performances are measured after coating.

[0077] Regarding the adhesion degree of the obtained seed treatment agent, the present invention does not observe the shedding situation on the seed surface by visual observation, but replaces it with the specific value of the determination of the coating shedding rate of the coated seeds. The determination method of the shedding rate is carried out according to 4.11 Determination of coating shedding rate in the aforesaid GB / T17768-1999 Specification for the preparation of suspension seed coating agent products (the same applies hereinafter). The detailed determination method is as follows:

[0078] Weigh two portions of seeds coated with 10 g (accurate to 0.002 g) of seed treatment agent (1 g of seed treatment preparation coats 200 g of seeds), and place them in Erlenmeyer flasks respectively. To one portion, accurately add 100 mL of ethanol, stopper it, place it in an ultrasonic cleaner and shake for 10 min to fully dissolve the coated seed coating agent. Take it out and let it stand for 10 min. Take 10.0 mL of the supernatant and transfer it to a 50 mL volumetric flask, dilute it to the mark with ethanol, and shake well to obtain Solution A.

[0079] Place the other portion on an oscillator, shake for 10 min, then carefully transfer the seeds to another Erlenmeyer flask, and obtain Solution B according to the treatment method of Solution A.

[0080] Using ethanol as the reference, measure the absorbance at a wavelength of 550 nm.

[0081] Calculate the coating shedding rate w4 (%), and calculate it according to the following formula:

[0082]

[0083] In the formula:

[0084] m0—the mass of the seeds after coating weighed for preparing Solution A;

[0085] m1—the mass of the seeds after coating weighed for preparing Solution B;

[0086] A0—the absorbance of Solution A;

[0087] A1—the absorbance of Solution B.

[0088] Table 1 Shedding rate

[0089] <![CDATA[m0]]> <![CDATA[m1]]> <![CDATA[A0]]> <![CDATA[A1]]> Drop-off rate (%) Example 5 10.0909 10.1931 0.56589 0.50940 10.88 Example 5-1 10.1023 10.0610 0.62381 0.58684 5.54 Example 6 10.0301 10.0898 0.81101 0.74517 8.66 Example 6-1 10.0108 10.1002 0.63351 0.61649 3.55 Example 7 10.0405 10.0144 0.69951 0.63286 9.29 Example 7-1 10.0543 10.0887 0.53043 0.50572 4.98 Example 8 10.0556 10.0217 0.51884 0.47026 9.06 Example 8-1 10.0543 10.0987 0.52543 0.51572 2.28 Example 9 10.0001 10.1087 0.66187 0.61001 8.83 Example 9-1 10.1008 10.0110 0.54561 0.53547 0.98 Example 10 10.0078 10.0221 0.61209 0.55981 8.68 Example 10-1 10.0401 10.0231 0.78887 0.78418 0.43

[0090] It can be seen from the above examples that for the two comparative examples in each example of the present invention, whether to add functional additives has a great influence on the coating brightness and shedding rate, that is, the adhesion degree of the key application performance of the preparation. The lower the value of the coating shedding rate, the better the adhesion ability of the coated seeds, and the better the application performance of the preparation. Generally speaking, the coating brightness of the preparation after adding functional additives has been significantly improved, solving the problem of the dullness of the existing compound flubenzimine used in the preparation; at the same time, the coating adhesion degree has been significantly improved by using the technology of the present invention, bringing significant effects, and playing a positive role in the application of flubenzimine in pesticides.

Claims

1. A preparation containing flubenzimine, characterized in that: The formulation is a powder, oil-dispersible powder, soluble tablet, soluble sol, oil agent, film-forming oil agent, dispersible liquid, paste, oil emulsion, fat agent, seed treatment dry powder, seed treatment dispersible powder, seed treatment liquid, seed treatment emulsion or seed treatment suspension containing flubendiamide; wherein, the mass of flubendiamide accounts for 2-70% of the formulation.

2. The preparation containing flubenzimine according to claim 1, characterized in that: In the formulation by mass percentage, flubendiamide is 2-70%, organic solvent is 0-15%, auxiliary agent is 8-50%, and carrier is 10-90%; the auxiliary agent is a surfactant and / or a functional auxiliary agent.

3. The formulation containing flubendiamide according to claim 2, characterized in that: In the powder by weight percentage, 2-70% is flubendiamide, 8-40% is surfactant, and the balance is carrier; In the oil-dispersible powder by weight percentage, 2-70% is flubendiamide, 8-40% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the soluble tablet by weight percentage, 2-70% is flubendiamide, 8-40% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the soluble sol by weight percentage, 2-70% is flubendiamide, 8-40% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the oil agent by weight percentage, 2-70% is flubendiamide, 2-20% is functional auxiliary agent, and the balance is organic solvent; In the film-forming oil agent by weight percentage, 2-70% is flubendiamide, 2-20% is functional auxiliary agent, and the balance is organic solvent; In the dispersible liquid by weight percentage, 2-70% is flubendiamide, 8-40% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the paste by weight percentage, 2-70% is flubendiamide, 6-30% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the oil emulsion by weight percentage, 2-70% is flubendiamide, 8-40% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the fat agent by weight percentage, 2-70% is flubendiamide, 6-30% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the paste by weight percentage, 2-70% is flubendiamide, 6-30% is surfactant, 1-15% is organic solvent, and the balance is carrier; In the seed treatment dry powder by weight percentage, 2-70% is flubendiamide, 6-30% is surfactant, 0-20% is functional auxiliary agent, and the balance is carrier; In the seed treatment dispersible powder by weight percentage, 2-70% is flubendiamide, 6-30% is surfactant, 0-20% is functional auxiliary agent, and the balance is carrier; In the seed treatment liquid by weight percentage, 2-70% is flubendiamide, 1-15% is organic solvent, 6-30% is surfactant, 0-20% is functional auxiliary agent, and the balance is water; In the seed treatment emulsion by weight percentage, 2-70% is flubendiamide, 1-15% is organic solvent, 6-30% is surfactant, 0-20% is functional auxiliary agent, and the balance is water; In the seed treatment suspension by weight percentage, 2-70% is flubendiamide, 6-20% is surfactant, 0-30% is functional auxiliary agent, and water makes up the balance.

4. The preparation containing flubenzimine according to claim 3, characterized in that: The carrier is one or more of water, light mineral oil, paraffin, kerosene, clay, diatomaceous earth, bentonite, kaolin, attapulgite, magnesium aluminum silicate, activated clay, silica white, light calcium carbonate, pottery clay, ammonium sulfate, montmorillonite.

5. The preparation containing flubenzimine according to claim 3, characterized in that: The organic solvent is one or more of aromatic hydrocarbons, chlorinated aromatic hydrocarbons, aliphatic hydrocarbons, chlorinated aliphatic hydrocarbons, alcohols and their ethers and esters, ketone compounds, vegetable oils, and methyl cellulose.

6. The preparation containing flubenzimine according to claim 5, characterized in that: The organic solvent is one or more of methanol, ethanol, isopropanol, butanol, ethylene glycol, ethylene glycol methyl ether, propylene glycol, glycerol, sorbitol, benzyl alcohol, furfuryl alcohol, cyclohexanol, acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone, N-methyl-pyrrolidone, N,N-dimethyl decanamide, N,N-dimethylacetamide, triethyl phosphate, tributyl phosphate, methyl oleate, dimethylformamide, dimethyl sulfoxide, methylated soybean oil, Armid DM10, Armid FMPC, Rhodiasolv Green SV-92, Rhodiasolv Green SV-33, Rhodiasolv Green 25, solvent oil S-150, solvent oil S-200.

7. The preparation containing flubenzimine according to claim 3, characterized in that: The surfactant is one or more of fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ether, acid alcohol ester and its polyoxyethylene ether, fatty amide and its polyoxyethylene ether, alkanolamide and its polyoxyethylene ether, polyoxyethylene-polyoxypropylene block copolymer, sodium alkyl naphthalene sulfonate fatty alcohol polyoxyethylene ether, sorbitan fatty acid ester polyoxyethylene ether.

8. The preparation containing flubenzimine according to claim 7, characterized in that: The surfactants are emulsifier SK-50EC, emulsifier SK-51EC, emulsifier 1601, emulsifier 0201B, emulsifier 0203B, emulsifier 500#, emulsifier 600#, emulsifier 700#, emulsifier NP-10, dispersant SK-33L, dispersant SK-33H, emulsifier OX-8686, emulsifier OX-2681, emulsifier 2201, emulsifier OX-690, dispersant DURAMAX TM D-205, dispersant DURAMAX TM D-305, dispersant DURAMAX TM W600, dispersant DURAMAX TM D800, emulsifier SK-5208T, emulsifier SK-5215T, emulsifier YUS-D625, emulsifier YUS-135B, emulsifier YUS-EC2200, emulsifier SK-5026ECH, emulsifier YUS-110, emulsifier SK-5212T, emulsifier YUS-A41B, emulsifier Emulson AG / 18C, Greenmul5100, TANEMULSPS29, D865, emulsifier YUS-2010CX, emulsifier S-80, emulsifier T-20, emulsifier SK-5935, dispersant YUS-D3020, dispersant SK-20TX, dispersant SD811, wetting agent SP-3266E, dispersant SP-2728, dispersant SP-SC29, dispersant SP-28F, dispersant SP-2750, dispersant TENSIOFIX SC, TENSIOFIX 96DB10, wetting agent TENSIOFIX BCZ, dispersant D425, dispersant YUS-FS1, dispersant YUS-FS3000, dispersant YUS-FS3300, dispersant YUS-FS7PG, dispersant YUS-TXC, dispersant SP-27001, Greensperse BE02, Greensperse BE23, TANEMUL DA2883, TANEMULDA2880, TANEMUL DA260, Atlox 4913, XN-45S, emulsifier 507, dispersant SK-33SC, dispersant SK-541, dispersant SK-551, dispersant SK-94S7, dispersant SK-551G, emulsifier SK-5218CP, emulsifier SK-5220T, dispersant SK-92FS1, emulsifier YUS-CP120, triphenylvinylphenol polyoxyethylene(n 20 )Triethanolamine salt of ether phosphoric acid, synergist SK-41G, synergist SK-41CN, synergist SK-41A, ULTRASURF OD21, ULTRASURF OD23, emulsifier YUS-OD1200, emulsifier AEO-3, dispersant SP-OF3468, dispersant SP-OF3472, G-VO / 02N, Greenmul EF68, Greenmul EF46, Atlox 4912, Atlox 4914, GR7M, emulsifier OX-635, emulsifier OX-622, emulsifier OX-653, emulsifier OX-667, emulsifier AEO-9, emulsifier T-85, dispersant YUS-5050PB, dispersant YUS-EP70G, dispersant YUS-WG5, SP-4302 (moisturizing synergist), dispersant VE / 10, dispersant OE / 02, dispersant OE / 03, dispersant OE / 08, dispersant OE / 09, dispersant OE150, dispersant Emulson CO40, dispersant Emulson AG / 1100, ULTRASURFO / 23, sodium salt of alkylnaphthalene sulfonic acid condensate, sodium methylnaphthalene sulfonate formaldehyde condensate, polycarboxylate dispersant GY-D800, polycarboxylate dispersant GY-D04, polycarboxylate dispersant GY-D02, naphthalene sulfonate formaldehyde condensate, sodium salt of naphthol sulfonic acid formaldehyde condensate, sodium methylene naphthalene sulfonate, sodium methylaminoethyl sulfonate of oleic acid, dispersant SP-SC3, Darun dispersant D909S, alkylnaphthalene sulfonate formaldehyde condensate (NNO), dispersant YUS-NV1420, dispersant YUS-WG4, dispersant YUS-WP1, dispersant YUS-CH7000, emulsifier PICO-LOE, dispersant PICO-CS300M, dispersant PICO-SF3, dispersant PICO-SWP1, dispersant PICO-SF1, dispersant Geropon Ultrasperse, dispersant GeroponExtra, dispersant Soprophor SC, dispersant Geropon DA1349, dispersant TENSIOFIX LX SPECIAL, dispersant TENSIOFIX DB08, dispersant Tensiofix AMS303, dispersant Tensiofix XA265, dispersant Tensiofix EW70, dispersant Tensiofix96DB10, dispersant SK-24R, dispersant SP-SC3275, dispersant SK-25CH, dispersant SK-34SC, dispersant YUS-CH1100, dispersant Supragil MNS / 90, dispersant Soprophor FD, dispersant Soprophor TSP / 461, dispersant SoprophorOne or more of 796 / P, dispersant SD819, dispersant Morwet D-400, dispersant Morwet D-360, dispersant Morwet D-390, dispersant Geronol ODessa 01, dispersant Geronol ODessa 05, dispersant YUS-D935, dispersant TANEMUL DA266, dispersant TANEMUL AG281, octylphenol polyoxyethylene ether sulfate, wetting agent Morwet EFW, wetting agent Igepal BC / 10, wetting agent GEROPON L-WET / P, wetting agent Supragil WP, wetting agent Supragil GN, wetting agent Rhodasurf 860 / p, emulsifier YUS-A51G, wetting agent YUS-LXC, wetting agent YUS-SXC, sodium isopropylnaphthalenesulfonate, sodium alkyl alcohol polyoxyethylene ether sulfate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkyl sulfosuccinate, sodium lauryl alcohol polyoxyethylene ether sulfonate, sodium dodecylbenzenesulfonate, sodium dodecyl sulfate, calcium dodecylbenzenesulfonate, calcium lignosulfonate, alkanoylaminotaurate.

9. The preparation containing flubenzimine according to claim 3, characterized in that: The functional auxiliary agent is one or more of SP-SC3275, polyvinyl alcohol, chitosan, warning color.

10. Use of the preparation containing flubenzimine as described in claim 1, characterized in that, The application of the preparation in controlling pests and / or mites.

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