Preparation method and preparation device of hedyotis diffusa water and readable storage medium

Abstract

The invention discloses a preparation method and a preparation device of hedyotis diffusa water and a readable storage medium. Comprising the following steps: acquiring distillate of oldenlandia diffusa; the distillate is analyzed, a liquid chromatogram of the distillate is obtained, and the liquid chromatogram comprises chromatographic peaks of substances contained in the distillate; based on the chromatographic peak, determining the specific type and content of a substance corresponding to the chromatographic peak; and preparing the hedyotis diffusa water according to the specific types and contents of substances corresponding to the chromatographic peaks. That is, in the application, the preparation standard for preparing the hedyotis diffusa water is determined equivalently, the hedyotis diffusa water can be prepared according to the preparation standard when the hedyotis diffusa water is subsequently prepared, the product quality control is realized, and the quality stability of the hedyotis diffusa water is ensured.

Description

Technical Field

[0001] This application belongs to the field of the preparation of Oldenlandia diffusa water, and specifically relates to a preparation method, a preparation device and a readable storage medium of Oldenlandia diffusa water. Background Art

[0002] With the improvement of living standards, Oldenlandia diffusa water has become a common drink in daily life. In the process of preparing Oldenlandia diffusa water, the distillate of Oldenlandia diffusa can be prepared first, and then Oldenlandia diffusa water is prepared based on the distillate. However, in actual production, there is a problem that the taste of Oldenlandia diffusa water is unstable. Summary of the Invention

[0003] The purpose of the embodiments of this application is to provide a preparation method, a preparation device and a readable storage medium of Oldenlandia diffusa water, in order to solve the problem that the taste of Oldenlandia diffusa water is unstable.

[0004] In the first aspect, the embodiments of this application provide a preparation method of Oldenlandia diffusa water, and the preparation method of Oldenlandia diffusa water includes: Obtain the distillate of Oldenlandia diffusa; Analyze the distillate to obtain the high performance liquid chromatography (HPLC) chromatogram of the distillate, and the HPLC chromatogram includes the chromatographic peaks of the substances contained in the distillate; Based on the chromatographic peaks, determine the specific types and contents of the substances corresponding to the chromatographic peaks; Prepare Oldenlandia diffusa water according to the specific types and contents of the substances corresponding to the chromatographic peaks.

[0005] Optionally, the step of based on the chromatographic peaks, determining the specific types and contents of the substances corresponding to the chromatographic peaks, includes: Obtain the target chromatographic peak according to the relative peak area in the chromatographic peaks; Determine the specific types and contents of the substances corresponding to the target chromatographic peak.

[0006] Optionally, the step of determining the specific types and contents of the substances corresponding to the target chromatographic peak, includes: Compare the target chromatographic peak with the chromatographic peak of the standard product; If the target chromatographic peak is the same as the chromatographic peak of the standard product, then take the substance type corresponding to the chromatographic peak of the standard product as the specific type of the substance corresponding to the target chromatographic peak, and determine the specific content of the substance corresponding to the target chromatographic peak.

[0007] Optionally, the step of determining the specific types and contents of the substances corresponding to the target chromatographic peak, includes: Collect the liquid chromatographic peaks of the distillate, and then perform nuclear magnetic resonance analysis to obtain the nuclear magnetic resonance result; Based on the nuclear magnetic resonance results, determine the specific type of the substance corresponding to the target chromatographic peak and determine the specific content of the substance corresponding to the target chromatographic peak.

[0008] Optionally, the determining the specific type and content of the substance corresponding to the chromatographic peak based on the chromatographic peak includes: Determine multiple groups of chromatographic peaks and determine the common peaks among the multiple groups of chromatographic peaks; Based on principal component analysis, extract the principal components with the criterion that λ is greater than 1, select the common peaks with a large contribution rate to the principal components to obtain the target chromatographic peak, where λ is the eigenvalue; Determine the specific type and content of the substance corresponding to the target chromatographic peak.

[0009] Optionally, the preparing the Oldenlandia diffusa water according to the specific type and content of the substance corresponding to the chromatographic peak includes: Record the specific type and content of the substance corresponding to the target chromatographic peak and use the specific type and content of the substance corresponding to the target chromatographic peak as the preparation standard; Determine whether the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate for preparing the Oldenlandia diffusa water; When the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate for preparing the Oldenlandia diffusa water, adjust the content of the substance corresponding to the target chromatographic peak in the distillate for preparing the Oldenlandia diffusa water to the content in the preparation standard, and prepare the Oldenlandia diffusa water according to the adjusted distillate; when the specific type of the substance corresponding to the target chromatographic peak is not contained in the distillate for preparing the Oldenlandia diffusa water, add the substance corresponding to the target chromatographic peak to the distillate and make the distillate after adding the substance corresponding to the target chromatographic peak meet the preparation standard, and prepare the Oldenlandia diffusa water according to the distillate that meets the preparation standard.

[0010] Optionally, the specific types of the substances corresponding to the target chromatographic peak are furoic acid and asperuloside.

[0011] Optionally, the analyzing the distillate to obtain the liquid chromatogram of the distillate includes: Determine the liquid chromatography analysis conditions, and perform liquid chromatography analysis on the distillate according to the liquid chromatography analysis conditions to obtain the liquid chromatogram of the distillate.

[0012] In a second aspect, an embodiment of the present application provides a device for preparing Oldenlandia diffusa water, and the device for preparing Oldenlandia diffusa water includes: An acquisition module, configured to acquire the distillate of Oldenlandia diffusa. An analysis module is used to analyze the distillate to obtain a liquid chromatogram of the distillate, and the liquid chromatogram includes chromatographic peaks of substances contained in the distillate; A determination module is used to determine the specific types and contents of substances corresponding to the chromatographic peaks based on the chromatographic peaks; A preparation module is used to prepare Oldenlandia diffusa water according to the specific types and contents of substances corresponding to the chromatographic peaks.

[0013] In a third aspect, an embodiment of the present application provides a readable storage medium, on which a program or instruction is stored, and when the program or instruction is executed by a processor, the steps of the method for preparing Oldenlandia diffusa water described in the first aspect above are implemented.

[0014] In a fourth aspect, an embodiment of the present application provides a chip, which includes a processor and a communication interface, the communication interface is coupled to the processor, and the processor is used to run a program or instruction to implement the method described in the first aspect.

[0015] In a fifth aspect, an embodiment of the present application provides a computer program product, which is stored in a storage medium, and the program product is executed by at least one processor to implement the method described in the first aspect.

[0016] In the embodiment of the present application, by obtaining the distillate of Oldenlandia diffusa, analyzing the distillate to obtain a liquid chromatogram of the distillate, the liquid chromatogram includes chromatographic peaks of substances contained in the distillate, based on the chromatographic peaks on the chromatogram, determining the specific types of substances corresponding to the chromatographic peaks, and preparing Oldenlandia diffusa water according to the specific types of substances corresponding to the chromatographic peaks. That is, in the embodiment of the present application, by determining the liquid chromatogram of the distillate and the specific types of substances corresponding to the chromatographic peaks, Oldenlandia diffusa water is prepared, so that the taste of Oldenlandia diffusa water is better and the quality is stable. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It represents a flowchart of a method for preparing Oldenlandia diffusa water provided by an embodiment of the present application; Figure 2 It represents a schematic diagram of a liquid chromatogram provided by an embodiment of the present application; Figure 3 It represents a schematic diagram of a device for preparing Oldenlandia diffusa water provided by an embodiment of the present application; Figure 4 It represents a schematic diagram of an electronic device provided by an embodiment of the present application.

[0018] Figure 5 It represents a schematic hardware structure diagram of an electronic device provided by an embodiment of the present application. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present application will be clearly described below with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present application belong to the scope of protection of the present application.

[0020] The terms "first", "second", etc. in the specification and claims of the present application are used to distinguish similar objects, rather than to describe a specific order or sequence. It should be understood that such data can be interchanged under appropriate circumstances so that the embodiments of the present application can be implemented in an order other than those illustrated or described herein, and the objects distinguished by "first", "second", etc. are usually of the same category, and the number of objects is not limited. For example, the first object can be one or more. In addition, "and / or" in the specification and claims means at least one of the connected objects, and the character " / " generally indicates an "or" relationship between the related objects before and after.

[0021] The method for analyzing human body images provided in the embodiments of the present application will be described in detail below with reference to the accompanying drawings through specific embodiments and their application scenarios.

[0022] Refer to Figure 1 , which shows a flowchart of a preparation method of Oldenlandia diffusa water provided in an embodiment of the present application. As Figure 1 shown, the preparation method of the Oldenlandia diffusa water includes: Step 101: Obtain the distillate of Oldenlandia diffusa.

[0023] Among them, the distillate of Oldenlandia diffusa can be purchased from a manufacturer, or the manufacturer can give the distillate of Oldenlandia diffusa as a gift. Or, Oldenlandia diffusa can be collected and then distilled to obtain the distillate of Oldenlandia diffusa. The embodiments of the present application do not limit the method for obtaining the distillate of Oldenlandia diffusa.

[0024] Step 102: Analyze the distillate to obtain a liquid chromatogram of the distillate, and the liquid chromatogram includes chromatographic peaks of substances contained in the distillate.

[0025] Specifically, the distillate can be analyzed according to the high performance liquid chromatography method to obtain the liquid chromatogram of the distillate. Among them, high performance liquid chromatography uses a high pressure liquid delivery system to pump a mobile phase such as a single solvent with different polarities or a mixed solvent with different ratios, a buffer solution, etc. into a chromatographic column filled with a stationary phase. After the components in the column are separated, they enter a detector for detection, thereby realizing the analysis of the sample.

[0026] It should be noted that in the embodiments of the present application, the liquid chromatogram is essentially a chromatogram, and the chromatogram has chromatographic peaks of the substances contained in the distillate. For example, in Figure 2 if the liquid chromatogram has 10 chromatographic peaks, it indicates that there are 10 substances in the distillate. That is, in the liquid chromatogram, one chromatographic peak represents one substance.

[0027] In addition, in some implementation manners, the implementation manner of step 102 can be: determining the liquid chromatography analysis conditions, and performing liquid chromatography analysis on the distillate according to the liquid chromatography analysis conditions to obtain the liquid chromatogram of the distillate.

[0028] Specifically, before performing high performance liquid chromatography analysis on the distillate, appropriate liquid chromatography analysis conditions can be determined first. The appropriate liquid chromatography analysis conditions can ensure that various components in the distillate can be efficiently separated during subsequent analysis of the distillate, so as to facilitate obtaining the liquid chromatogram of the distillate.

[0029] It should be noted that in the present application, when performing analysis by high performance liquid chromatography, an analytical instrument can be used for analysis. The liquids added in the analytical instrument are mainly methanol and acetic acid water, and the ratio of methanol to acetic acid water is 25:75. The acetic acid water can be 0.05% acetic acid water. The column temperature of the chromatographic column in the analytical instrument is 30 °C, the flow rate is 1 ml / min, and the injection volume of the analytical instrument is 20 μl. Thus, these conditions constitute appropriate liquid chromatography analysis conditions.

[0030] Step 103: Based on the chromatographic peaks, determine the specific types and contents of the substances corresponding to the chromatographic peaks.

[0031] Among them, the liquid chromatogram has multiple chromatographic peaks, so that the specific types of the substances corresponding to each chromatographic peak can be determined, and thus the types of the substances contained in the distillate can be determined more accurately through the liquid chromatogram.

[0032] In addition, in some implementation manners, the implementation manner of step 103 can be: obtaining a target chromatographic peak according to the relative peak area in the chromatographic peaks; determining the specific types and contents of the substances corresponding to the target chromatographic peak.

[0033] Among them, after obtaining the liquid chromatogram, the number of chromatographic peaks on the liquid chromatogram may be multiple, and the peak areas of different chromatographic peaks may be different. The target chromatographic peak can be obtained according to the relative peak area. Among them, the substance corresponding to the target chromatographic peak may be the main substance contained in the distillate, so it is necessary to determine the specific type of the substance corresponding to the target chromatographic peak. After determining the substance corresponding to the target chromatographic peak, the content of the substance can be directly measured. In addition, when the chromatographic peak on the liquid chromatogram is greater than or equal to the chromatographic peak threshold, the peak shape of the chromatographic peak is relatively sharp and the resolution is high, which is also convenient for identification.

[0034] It should be noted that the relative peak area of the chromatographic peak can be selected according to actual needs, and the embodiments of the present application do not limit this here.

[0035] In addition, in some implementation manners, the implementation manner for determining the specific type and content of the substance corresponding to the target chromatographic peak may be: comparing the target chromatographic peak with the chromatographic peaks of the reference standards; if the target chromatographic peak is the same as the chromatographic peak of the reference standard, then taking the type of the substance corresponding to the chromatographic peak of the reference standard as the specific type of the substance corresponding to the target chromatographic peak.

[0036] Among them, the type of the substance corresponding to the chromatographic peak of the reference standard has been determined. Therefore, comparing the target chromatographic peak with the chromatographic peak of the reference standard is equivalent to comparing the target chromatographic peak with the chromatographic peak of which the specific substance type is already known. If the two are the same, or the deviation value between the two is within the preset deviation range, it indicates that the type of the substance corresponding to the target chromatographic peak is the same as the type of the substance corresponding to the chromatographic peak of the reference standard, and then the type of the substance corresponding to the chromatographic peak of the reference standard can be directly taken as the specific type of the substance corresponding to the target chromatographic peak.

[0037] For example, the specific types of the substances corresponding to multiple chromatographic peaks of the reference standard are p-hydroxybenzoic acid and geniposide respectively. After obtaining the liquid chromatography, comparing the target chromatographic peak on the liquid chromatography with the multiple chromatographic peaks of the reference standard. If the target chromatographic peak is the same as the chromatographic peak of a reference standard, and the specific type of the substance corresponding to the chromatographic peak of this reference standard is geniposide, then the specific type of the substance corresponding to the target chromatographic peak can be determined to be geniposide.

[0038] It should be noted that in the embodiments of the present application, the number of target chromatographic peaks may be multiple. At this time, each target chromatographic peak needs to be compared with the chromatographic peak of the reference standard, so as to determine the specific type of the substance corresponding to each target chromatographic peak. For example, if 5 target chromatographic peaks are determined, each of the 5 target chromatographic peaks needs to be compared with the chromatographic peak of the reference standard to determine the specific type of the substance corresponding to each standard chromatographic peak.

[0039] In addition, in the embodiments of the present application, the substance corresponding to each target chromatographic peak can also be used as a quality marker, and then the content range of the quality marker can be detected in the distillate.

[0040] In addition, in some implementation manners, the implementation manner for determining the specific type and content of the substance corresponding to the target chromatographic peak may be: separately collecting the chromatographic peaks of the substances contained in the distillate, and then performing nuclear magnetic resonance analysis to obtain nuclear magnetic resonance results; according to the nuclear magnetic resonance results, determining the specific type of the substance corresponding to the target chromatographic peak and determining the specific content of the substance corresponding to the target chromatographic peak.

[0041] Among them, when determining the specific type of the substance corresponding to the target chromatographic peak, if there is no standard sample for comparison and thus the specific type of the substance corresponding to the target chromatographic peak cannot be determined, it is necessary to collect the chromatographic peak and perform nuclear magnetic resonance analysis, that is, use nuclear magnetic resonance equipment to perform nuclear magnetic resonance operation on the chromatographic peak to obtain nuclear magnetic resonance results. By interpreting the nuclear magnetic resonance spectrum, the type of the specific substance can be known, and thus the specific type of the substance corresponding to the target chromatographic peak can be determined according to the nuclear magnetic resonance structure. Once the specific type of the substance corresponding to the target chromatographic peak is determined, the distillate can be measured to obtain the specific content of the substance corresponding to the target chromatographic peak, and the specific type and content of the substance corresponding to the target chromatographic peak in the distillate are obtained.

[0042] In addition, in the embodiments of the present application, when determining the specific content of the substance corresponding to the target chromatographic peak, the target chromatographic peak can also be compared with the chromatographic peak of the standard sample first. If at least some of the target chromatographic peaks in the target chromatographic peak are the same as the chromatographic peak of the standard sample, the specific type of the substance corresponding to the chromatographic peak of the standard sample is used as the specific type of the substance corresponding to this part of the target chromatographic peak, and the target chromatographic peaks different from the chromatographic peak of the standard sample are collected and nuclear magnetic resonance analysis is performed to obtain the nuclear magnetic resonance structure, and then the specific type of the substance corresponding to the target chromatographic peak is determined.

[0043] In addition, in some implementation manners, the implementation manner of step 103 can be: determining multiple groups of chromatographic peaks and determining the common peaks of the multiple groups of chromatographic peaks; based on principal component analysis, extracting the principal components with the criterion that λ is greater than 1, and selecting the common peaks with a large contribution rate to the principal components to obtain the target chromatographic peak, where λ is the eigenvalue; determining the specific type and content of the substance corresponding to the target chromatographic peak.

[0044] Among them, multiple batches of distillates can be processed according to the high performance liquid chromatography method to obtain multiple groups of liquid chromatography diagrams. Each group of liquid chromatography diagrams corresponds to the chromatographic peaks of the substances contained in the distillate of the batch, so that the chromatographic peaks that appear simultaneously in multiple groups of chromatographic peaks can be determined, that is, the common peaks that exist simultaneously in multiple groups of chromatographic peaks are determined. Then, based on principal component analysis, the principal components are extracted with the criterion that λ is greater than 1, and the common peaks with a large contribution rate to the principal components are selected to obtain the target chromatographic peak. λ is the eigenvalue, which is equivalent to determining the chromatographic peaks with an eigenvalue greater than 1 among the common peaks, extracting the principal components, and then the specific type and content of the substance corresponding to the target chromatographic peak can be determined. Among them, the common peaks greater than or equal to the principal component contribution rate threshold can be selected. For example, the principal component contribution rate threshold is 80%, or for another example, the principal component contribution rate threshold is 85%. In this regard, the present application does not make any limitation here.

[0045] It should be noted that in mathematical derivations, the eigenvector corresponding to an eigenvalue is the correct coordinate axis we ideally want to obtain, and the eigenvalue is equal to the variance on the corresponding dimension of the coordinates after data rotation. Therefore, in data mining, we directly use the eigenvalue to describe the amount of information contained in the corresponding eigenvector, and the value of a certain eigenvalue divided by the sum of all eigenvalues is the variance contribution rate of the eigenvector. Thus, using this idea, in this application, we extract the principal components with the criterion that λ is greater than 1, so as to ensure that the extracted principal components are the principal components in the distillate.

[0046] In addition, we determine the chromatographic peaks that appear in multiple groups of chromatographic peaks, which is equivalent to determining the substances that coexist in multiple batches of distillate. Usually, the distillate is made from Hedyotis diffusa, but due to reasons such as origin and climate, the substance components in the prepared distillate may be different. In this application, determining the chromatographic peaks that appear in multiple groups of chromatographic peaks is equivalent to determining the substances that coexist in multiple batches of distillate, indicating that these substances are relatively stable and have a key impact on the taste of the prepared Hedyotis diffusa water. Thus, based on the substances that coexist in multiple batches of distillate determined later, we can more accurately guide the preparation of Hedyotis diffusa water to ensure the stable taste of the prepared Hedyotis diffusa water.

[0047] In addition, in some implementation manners, the implementation manner of step 103 can be: determining the eigenvalue of each chromatographic peak, and taking the chromatographic peaks with eigenvalues greater than the preset eigenvalue as target chromatographic peaks.

[0048] Among them, the eigenvalue of each chromatographic peak can be determined by software, and then the chromatographic peaks with eigenvalues greater than the preset eigenvalue can be taken as target chromatographic peaks. Among them, the software can be the similarity evaluation system for traditional Chinese medicine chromatographic fingerprint spectra in the prior art.

[0049] In addition, the preset eigenvalue can be set according to actual needs. For example, the preset eigenvalue is 1, or for another example, the preset eigenvalue is 0.9. In this regard, the embodiments of this application do not make any limitations here.

[0050] Step 104: Prepare Hedyotis diffusa water according to the specific types and contents of the substances corresponding to the chromatographic peaks.

[0051] Once the specific types of the substances corresponding to the chromatographic peaks are determined, which is equivalent to determining the specific substances, Hedyotis diffusa water can be prepared.

[0052] In addition, in some implementation manners, the implementation manner of step 104 may be: recording the specific type and content of the substance corresponding to the target chromatographic peak, and using the specific type and content of the substance corresponding to the target chromatographic peak as the preparation standard; determining whether the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate of the Oldenlandia diffusa water to be prepared; when the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate of the Oldenlandia diffusa water to be prepared, adjusting the content of the substance corresponding to the target chromatographic peak in the distillate of the Oldenlandia diffusa water to be prepared to the content in the preparation standard, and preparing the Oldenlandia diffusa water according to the adjusted distillate; when the specific type of the substance corresponding to the target chromatographic peak is not contained in the distillate of the Oldenlandia diffusa water to be prepared, adding the substance corresponding to the target chromatographic peak to the distillate, and making the distillate after adding the substance corresponding to the target chromatographic peak meet the preparation standard, and preparing the Oldenlandia diffusa water according to the distillate that meets the preparation standard.

[0053] Among them, after determining the specific type and content of the substance corresponding to the target chromatographic peak, the specific type and content of the substance corresponding to the target chromatographic peak can be recorded, and the specific type and content of the substance corresponding to the target chromatographic peak are used as the preparation standard for subsequent preparation of Oldenlandia diffusa water. Subsequently, when preparing Oldenlandia diffusa water from the distillate, it is determined whether the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate of the Oldenlandia diffusa water to be prepared. Once the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate of the Oldenlandia diffusa water to be prepared, the content of the substance corresponding to the target chromatographic peak in the distillate of the Oldenlandia diffusa water to be prepared can be determined. If the content is the same as the content in the preparation standard, the Oldenlandia diffusa water is directly prepared from the distillate. If the content is different from the content in the preparation standard, the content of the substance corresponding to the target chromatographic peak in the distillate of the Oldenlandia diffusa water to be prepared needs to be adjusted to the content in the preparation standard, and then the adjusted distillate is prepared into Oldenlandia diffusa water. That is, by determining the preparation standard, it provides a basis for subsequent preparation of Oldenlandia diffusa water, making the taste of the prepared Oldenlandia diffusa water stable.

[0054] Once the specific type of the substance corresponding to the target chromatographic peak is not contained in the distillate of the Oldenlandia diffusa water to be prepared, the substance corresponding to the target chromatographic peak is added to the distillate, and the distillate after adding the substance corresponding to the target chromatographic peak meets the preparation standard, and the Oldenlandia diffusa water is prepared according to the distillate that meets the preparation standard, which can also make the taste of the prepared Oldenlandia diffusa water stable.

[0055] In addition, in some implementation manners, the implementation manner of step 104 may be: preparing Oldenlandia diffusa water according to the specific type and content of the substance corresponding to the target chromatographic peak.

[0056] Among them, after determining the target chromatographic peak on the liquid chromatography spectrum, once the specific type of the substance corresponding to the target chromatographic peak is determined, the Herba Hedyotis Diffusae water can be directly prepared from the specific type of the substance corresponding to the target chromatographic peak. For example, if the specific types of the substances corresponding to the target chromatographic peak are p-hydroxybenzoic acid, asperuloside, and geniposide, the Herba Hedyotis Diffusae water can be directly prepared from p-hydroxybenzoic acid, asperuloside, and geniposide.

[0057] In addition, in some implementation manners, the implementation manner of step 104 can be: determining the target substance according to the specific type of the substance corresponding to the chromatographic peak; mixing the target substance with the liquid to be mixed to form the Herba Hedyotis Diffusae water.

[0058] Among them, once the specific type of the substance corresponding to the chromatographic peak is determined, the specific type of this substance is a specific substance, and this specific substance can be used as the target substance. For example, if the specific type of the substance corresponding to the chromatographic peak is p-hydroxybenzoic acid, p-hydroxybenzoic acid can be used as the target substance.

[0059] In addition, once the target substance is determined, the target substance can be mixed with the liquid to be mixed. When the target substance is dissolved in the mixed liquid, the Herba Hedyotis Diffusae water is formed. Among them, the liquid to be mixed can be the distilled liquid of Herba Hedyotis Diffusae that does not contain the target substance. After diluting the distilled liquid, the Herba Hedyotis Diffusae water can be obtained.

[0060] It should be noted that the number of target substances can be multiple. At this time, multiple target substances can be mixed with the liquid to be mixed to form the Herba Hedyotis Diffusae water. That is, multiple target substances are added to the mixed liquid to form the Herba Hedyotis Diffusae water. For example, if the multiple target substances are p-hydroxybenzoic acid, asperuloside, and geniposide respectively, p-hydroxybenzoic acid, asperuloside, and geniposide can be added to the liquid to be mixed to form the Herba Hedyotis Diffusae water.

[0061] In addition, in some implementation manners, after mixing the target substance with the liquid to be mixed to form the Herba Hedyotis Diffusae water, the preparation method can further include: measuring the sensory index of the Herba Hedyotis Diffusae water; if the sensory index of the Herba Hedyotis Diffusae water does not meet the requirements, then increase or decrease the dosage of the target substance, form the Herba Hedyotis Diffusae water again, and measure the sensory index of the Herba Hedyotis Diffusae water until the sensory index of the Herba Hedyotis Diffusae water meets the requirements.

[0062] Among them, the sensory index of the Oldenlandia diffusa water can be measured by an electronic tongue, that is, the taste of the Oldenlandia diffusa water is measured. Once the taste of the Oldenlandia diffusa water does not meet the requirements, the dosage of the target substance can be increased to form the Oldenlandia diffusa water again, and then the taste of the Oldenlandia diffusa water is measured again. If it still does not meet the requirements, the dosage of the target substance is increased until the taste of the Oldenlandia diffusa water meets the requirements; of course, once the taste of the Oldenlandia diffusa water does not meet the requirements, the dosage of the target substance can be reduced to form the Oldenlandia diffusa water again, and then the taste of the Oldenlandia diffusa water is measured again. If it still does not meet the requirements, the dosage of the target substance is reduced until the taste of the Oldenlandia diffusa water meets the requirements. Thus, the taste of the formed Oldenlandia diffusa water can meet the requirements.

[0063] In the embodiment of the present application, the distillate of Oldenlandia diffusa is obtained; the distillate is analyzed to obtain the liquid chromatogram of the distillate, and the chromatogram peaks of the substances contained in the distillate are included in the liquid chromatogram; based on the chromatogram peaks, the specific types and contents of the substances corresponding to the chromatogram peaks are determined; according to the specific types and contents of the substances corresponding to the chromatogram peaks, the Oldenlandia diffusa water is prepared. That is, in the embodiment of the present application, by determining the liquid chromatogram of the distillate, the specific types of the substances corresponding to the chromatogram peaks can be determined more accurately. After that, through the specific types and contents of the substances corresponding to the chromatogram peaks, it is equivalent to determining the preparation standard for preparing the Oldenlandia diffusa water. When preparing the Oldenlandia diffusa water subsequently, the Oldenlandia diffusa water can be prepared according to this preparation standard to ensure the stable quality of the Oldenlandia diffusa water and achieve product quality control.

[0064] The embodiment of the present application provides a preparation device for Oldenlandia diffusa water, as Figure 3 shown. The preparation device 200 for Oldenlandia diffusa water includes: An acquisition module 201, configured to acquire the distillate of Oldenlandia diffusa; An analysis module 202, configured to analyze the distillate to obtain the liquid chromatogram of the distillate, and the chromatogram peaks of the substances contained in the distillate are included in the liquid chromatogram; A determination module 203, configured to determine the specific types and contents of the substances corresponding to the chromatogram peaks based on the chromatogram peaks; A preparation module 204, configured to prepare the Oldenlandia diffusa water according to the specific types and contents of the substances corresponding to the chromatogram peaks.

[0065] Optionally, the determination module 203 is further configured to: determine the chromatogram peaks greater than or equal to the chromatogram peak threshold in the chromatogram peaks to obtain the target chromatogram peaks; determine the specific types and contents of the substances corresponding to the target chromatogram peaks.

[0066] Optionally, the determination module 203 is further configured to: compare the target chromatographic peak with the chromatographic peak of the reference substance; if the target chromatographic peak is the same as the chromatographic peak of the reference substance, use the substance type corresponding to the chromatographic peak of the reference substance as the specific type of the substance corresponding to the target chromatographic peak, and determine the specific content of the substance corresponding to the target chromatographic peak.

[0067] Optionally, the determination module 203 is further configured to: collect the chromatographic peaks of the substances contained in the distillate, and then perform nuclear magnetic resonance analysis to obtain a nuclear magnetic resonance result; Based on the nuclear magnetic resonance result, determine the specific type of the substance corresponding to the target chromatographic peak, and determine the specific content of the substance corresponding to the target chromatographic peak.

[0068] Optionally, the preparation module 204 is further configured to: collect the chromatographic peaks of the substances contained in the distillate, and then perform nuclear magnetic resonance analysis to obtain a nuclear magnetic resonance result; based on the nuclear magnetic resonance result, determine the specific type of the substance corresponding to the target chromatographic peak, and determine the specific content of the substance corresponding to the target chromatographic peak.

[0069] Optionally, the determination module 203 is further configured to: determine multiple groups of chromatographic peaks, and determine the common peaks among the multiple groups of chromatographic peaks; based on principal component analysis, extract the principal components with the eigenvalue λ greater than 1 as the standard, and select the common peaks with a large contribution rate to the principal components to obtain the target chromatographic peak, where λ is the eigenvalue; determine the specific type and content of the substance corresponding to the target chromatographic peak.

[0070] Optionally, the preparation module 204 is further configured to: record the specific type and content of the substance corresponding to the target chromatographic peak, and use the specific type and content of the substance corresponding to the target chromatographic peak as the preparation standard; determine whether the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate of the water of Oldenlandia diffusa to be prepared; when the specific type of the substance corresponding to the target chromatographic peak is contained in the distillate of the water of Oldenlandia diffusa to be prepared, adjust the content of the substance corresponding to the target chromatographic peak in the distillate of the water of Oldenlandia diffusa to be prepared to the content in the preparation standard, and prepare the water of Oldenlandia diffusa according to the adjusted distillate; when the specific type of the substance corresponding to the target chromatographic peak is not contained in the distillate of the water of Oldenlandia diffusa to be prepared, add the substance corresponding to the target chromatographic peak to the distillate, and make the distillate after adding the substance corresponding to the target chromatographic peak meet the preparation standard, and prepare the water of Oldenlandia diffusa according to the distillate that meets the preparation standard.

[0071] In the embodiments of the present application, by obtaining the distillate of Hedyotis diffusa; analyzing the distillate to obtain a liquid chromatogram of the distillate, and the liquid chromatogram includes chromatographic peaks of substances contained in the distillate; based on the chromatographic peaks, determining the specific types and contents of the substances corresponding to the chromatographic peaks; and preparing Hedyotis diffusa water according to the specific types and contents of the substances corresponding to the chromatographic peaks. That is, in the embodiments of the present application, by determining the liquid chromatogram of the distillate, the specific types of the substances corresponding to the chromatographic peaks can be determined more accurately. Then, through the specific types and contents of the substances corresponding to the chromatographic peaks, it is equivalent to determining the preparation standard for preparing Hedyotis diffusa water. When preparing Hedyotis diffusa water subsequently, Hedyotis diffusa water can be prepared according to this preparation standard, so that the taste of the prepared Hedyotis diffusa water is stable, quality control is achieved, and the quality of Hedyotis diffusa water is ensured to be stable.

[0072] Optionally, as Figure 4 shown, the embodiments of the present application further provide an electronic device 300, including a processor 301 and a memory 302. A program or instruction that can run on the processor 301 is stored on the memory 302. When the program or instruction is executed by the processor 301, each step of the above-mentioned embodiment of the preparation method of Hedyotis diffusa water is implemented, and the same technical effects can be achieved. To avoid repetition, it will not be elaborated here.

[0073] Figure 5 It is a schematic diagram of the hardware structure of an electronic device for implementing the embodiments of the present application.

[0074] The electronic device 1000 includes, but is not limited to: a radio frequency unit 1001, a network module 1002, an audio output unit 1003, an input unit 1004, a sensor 1005, a display unit 1006, a user input unit 1007, an interface unit 1008, a memory 1009, and a processor 1010, etc.

[0075] Those skilled in the art can understand that the electronic device 1000 may further include a power supply (such as a battery) for supplying power to each component. The power supply can be logically connected to the processor 1010 through a power management system, so as to implement functions such as management of charging, discharging, and power consumption management through the power management system. Figure 4 The structure of the electronic device shown in does not constitute a limitation on the electronic device. The electronic device may include more or fewer components than shown, or combine certain components, or have different component arrangements, which will not be elaborated here.

[0076] Among them, the processor 1010 is configured to obtain the distillate of Oldenlandia diffusa; analyze the distillate to obtain a liquid chromatogram of the distillate, where the liquid chromatogram includes chromatographic peaks of substances contained in the distillate; determine the specific types and contents of the substances corresponding to the chromatographic peaks based on the chromatographic peaks; and prepare Oldenlandia diffusa water according to the specific types and contents of the substances corresponding to the chromatographic peaks.

[0077] In the embodiment of the present application, by obtaining the distillate of Oldenlandia diffusa; analyzing the distillate to obtain a liquid chromatogram of the distillate, where the liquid chromatogram includes chromatographic peaks of substances contained in the distillate; determining the specific types and contents of the substances corresponding to the chromatographic peaks based on the chromatographic peaks; and preparing Oldenlandia diffusa water according to the specific types and contents of the substances corresponding to the chromatographic peaks. That is, in the embodiment of the present application, by determining the liquid chromatogram of the distillate, the specific types of the substances corresponding to the chromatographic peaks can be determined more accurately. Then, by the specific types and contents of the substances corresponding to the chromatographic peaks, it is equivalent to determining the preparation standard for preparing Oldenlandia diffusa water. When preparing Oldenlandia diffusa water subsequently, the Oldenlandia diffusa water can be prepared according to this preparation standard, so that the taste of the prepared Oldenlandia diffusa water is stable, realizing quality control and ensuring the stable quality of Oldenlandia diffusa water.

[0078] It should be understood that in the embodiment of the present application, the input unit 1004 may include a Graphics Processing Unit (GPU) 10041 and a microphone 10042. The graphics processor 10041 processes the image data of static pictures or videos obtained by an image capture device (such as a camera) in a video capture mode or an image capture mode. The display unit 1006 may include a display panel 10061, and the display panel 10061 may be configured in the form of a liquid crystal display, an organic light emitting diode, etc. The user input unit 1007 includes at least one of a touch panel 10071 and other input devices 10072. The touch panel 10071 is also called a touch screen. The touch panel 10071 may include a touch analysis device and a touch controller. The other input devices 10072 may include, but are not limited to, a physical keyboard, function keys (such as volume control keys, switch keys, etc.), a trackball, a mouse, and a joystick, which will not be elaborated here.

[0079] The memory 1009 can be used to store software programs and various data. The memory 1009 may mainly include a first storage area for storing programs or instructions and a second storage area for storing data. Among them, the first storage area may store an operating system, application programs or instructions required for at least one function (such as a sound playback function, an image playback function, etc.). In addition, the memory 1009 may include a volatile memory or a non-volatile memory, or the memory 1009 may include both a volatile memory and a non-volatile memory. Among them, the non-volatile memory may be a read-only memory (ROM), a programmable read-only memory (PROM), an erasable programmable read-only memory (EPROM), an electrically erasable programmable read-only memory (EEPROM), or a flash memory. The volatile memory may be a random access memory (RAM), a static random access memory (SRAM), a dynamic random access memory (DRAM), a synchronous dynamic random access memory (SDRAM), a double data rate synchronous dynamic random access memory (DDR SDRAM), an enhanced synchronous dynamic random access memory (ESDRAM), a synch link dynamic random access memory (SLDRAM), and a direct rambus random access memory (DRRAM). The memory 1009 in the embodiments of the present application includes, but is not limited to, these and any other suitable types of memories.

[0080] The processor 1010 may include one or more processing units; optionally, the processor 1010 integrates an application processor and a modem processor. Among them, the application processor mainly processes operations related to the operating system, user interface, and application programs, etc., and the modem processor mainly processes wireless communication signals, such as a baseband processor. It can be understood that the above modem processor may not be integrated into the processor 1010 either.

[0081] The embodiments of the present application provide a computer program product. The program product is stored in a storage medium and is executed by at least one processor to implement the various processes of the embodiments of the preparation method of the above-mentioned Herba Hedyotis Diffusae Water, and can achieve the same technical effects. To avoid repetition, it will not be elaborated here.

[0082] It should be noted that in this text, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not explicitly listed, or elements inherent to such a process, method, article or device. Without further limitation, an element defined by the statement "including one..." does not exclude the existence of another identical element in the process, method, article or device including that element. In addition, it should be pointed out that the scope of the methods and devices in the embodiments of the present application is not limited to performing functions in the order shown or discussed, but may also include performing functions in a substantially simultaneous manner or in the reverse order according to the functions involved. For example, the described methods may be performed in an order different from that described, and various steps may be added, omitted, or combined. Additionally, the features described with reference to certain examples may be combined in other examples.

[0083] From the description of the above embodiments, those skilled in the art can clearly understand that the above-described example methods can be implemented by means of software plus a necessary general hardware platform. Of course, they can also be implemented by hardware, but in many cases the former is a better implementation. Based on this understanding, the technical solution of the present application, in essence or the part that contributes to the prior art, can be embodied in the form of a computer software product. This computer software product is stored in a storage medium (such as ROM / RAM, magnetic disk, optical disk) and includes several instructions to cause a terminal (which can be a mobile phone, computer, server, or network device, etc.) to execute the methods described in the various embodiments of the present application.

[0084] The embodiments of the present application have been described above with reference to the accompanying drawings. However, the present application is not limited to the above specific embodiments. The above specific embodiments are merely illustrative and not restrictive. Under the inspiration of the present application, those of ordinary skill in the art can also make many forms without departing from the purpose of the present application and the scope protected by the claims, and all of them belong to the protection scope of the present application.

Claims

1. A preparation method of Oldenlandia diffusa water, characterized in that The preparation method of the Oldenlandia diffusa water includes: Obtaining the distillate of Oldenlandia diffusa; Analyzing the distillate to obtain the liquid chromatogram of the distillate, and the liquid chromatogram includes the chromatographic peaks of the substances contained in the distillate; Based on the chromatographic peaks, determining the specific types and contents of the substances corresponding to the chromatographic peaks; Preparing the Oldenlandia diffusa water according to the specific types and contents of the substances corresponding to the chromatographic peaks.

2. The preparation method of the Herba Hedyotidis Diffusae water according to claim 1, characterized in that, The determining the specific types and contents of the substances corresponding to the chromatographic peaks based on the chromatographic peaks includes: Obtaining target chromatographic peaks according to the relative peak areas in the chromatographic peaks; Determining the specific types and contents of the substances corresponding to the target chromatographic peaks.

3. The preparation method of Oldenlandia diffusa water according to claim 2, characterized in that The determining the specific types and contents of the substances corresponding to the target chromatographic peaks includes: Comparing the target chromatographic peaks with the chromatographic peaks of the reference standards; If the target chromatographic peaks are the same as the chromatographic peaks of the reference standards, taking the substance types corresponding to the chromatographic peaks of the reference standards as the specific types of the substances corresponding to the target chromatographic peaks, and determining the specific contents of the substances corresponding to the target chromatographic peaks.

4. The preparation method of the Oldenlandia diffusa water according to claim 2, characterized in that The determining the specific types and contents of the substances corresponding to the target chromatographic peaks includes: Collecting the chromatographic peaks of the substances contained in the distillate, and then performing nuclear magnetic resonance analysis to obtain nuclear magnetic resonance results; Based on the nuclear magnetic resonance results, determining the specific types of the substances corresponding to the target chromatographic peaks, and determining the specific contents of the substances corresponding to the target chromatographic peaks.

5. The preparation method of Oldenlandia diffusa water according to claim 1, characterized in that, The determining the specific types and contents of the substances corresponding to the chromatographic peaks based on the chromatographic peaks includes: Determining multiple groups of chromatographic peaks, and determining the common peaks among the multiple groups of chromatographic peaks; Based on principal component analysis, extracting principal components with the criterion of λ greater than 1, and selecting the common peaks with a large contribution rate to the principal components to obtain target chromatographic peaks, where λ is the eigenvalue; Determining the specific types and contents of the substances corresponding to the target chromatographic peaks.

6. The preparation method of Oldenlandia diffusa water according to claim 2 or 5, characterized in that, The preparing the Oldenlandia diffusa water according to the specific types and contents of the substances corresponding to the chromatographic peaks includes: Recording the specific types and contents of the substances corresponding to the target chromatographic peaks, and taking the specific types and contents of the substances corresponding to the target chromatographic peaks as the preparation standards; Determining whether the specific types of the substances corresponding to the target chromatographic peaks are contained in the distillate of the Oldenlandia diffusa water to be prepared; When the specific types of the substances corresponding to the target chromatographic peaks are contained in the distillate of the Oldenlandia diffusa water to be prepared, adjusting the content of the substances corresponding to the target chromatographic peaks in the distillate of the Oldenlandia diffusa water to be prepared to the content in the preparation standards, and preparing the Oldenlandia diffusa water according to the adjusted distillate; when the specific types of the substances corresponding to the target chromatographic peaks are not contained in the distillate of the Oldenlandia diffusa water to be prepared, adding the substances corresponding to the target chromatographic peaks to the distillate, and making the distillate after adding the substances corresponding to the target chromatographic peaks meet the preparation standards, and preparing the Oldenlandia diffusa water according to the distillate meeting the preparation standards.

7. The preparation method of Oldenlandia diffusa water according to claim 2 or 5, characterized in that, The specific types of the substances corresponding to the target chromatographic peaks are furoic acid and asperuloside.

8. The preparation method of the Herba Hedyotis Diffusae water according to claim 1, characterized in that, Analyzing the distillate to obtain a liquid chromatogram of the distillate, including: Determining liquid chromatography analysis conditions, and performing liquid chromatography analysis on the distillate according to the liquid chromatography analysis conditions to obtain a liquid chromatogram of the distillate.

9. A preparation device for Oldenlandia diffusa water, characterized in that, The preparation device for Oldenlandia diffusa water includes: An acquisition module for acquiring the distillate of Oldenlandia diffusa; An analysis module for analyzing the distillate to obtain a liquid chromatogram of the distillate, and the liquid chromatogram includes chromatographic peaks of substances contained in the distillate; A determination module for determining the specific types and contents of substances corresponding to the chromatographic peaks based on the chromatographic peaks; A preparation module for preparing Oldenlandia diffusa water according to the specific types and contents of substances corresponding to the chromatographic peaks.

10. A readable storage medium, characterized in that, A program or instruction is stored on the readable storage medium, and when the program or instruction is executed by a processor, the steps of the preparation method for Oldenlandia diffusa water according to any one of claims 1-7 are implemented.

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