Tablet for hot compress treatment of influenza and preparation method thereof

Abstract

The invention discloses a tablet for treating influenza through hot compress and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine tablets. The traditional Chinese medicine tablet capable of treating influenza and new crown sequelae is prepared from the following components in parts by weight: 5-15 parts of radix bupleuri, 5-15 parts of codonopsis pilosula, 5-15 parts of angelica sinensis, 3-13 parts of honeysuckle, 7-17 parts of fructus forsythiae, 3-13 parts of selfheal, 5-15 parts of coptis chinensis, 5-15 parts of golden cypress and 3-13 parts of safflower.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine tablets, and specifically to a tablet for hot compress treatment of influenza and its preparation method. Background Art

[0002] With the development of modern medicine, antiviral drugs and antibiotics are widely used in the treatment of respiratory infectious diseases such as influenza. However, long-term use is likely to cause side effects such as drug resistance, liver and kidney damage. Especially in the treatment of the sequelae of novel coronavirus infection, some patients have limitations in the tolerance and persistence of western medicine treatment. Although traditional Chinese medicine has unique advantages in clearing heat and detoxifying, strengthening the healthy qi and eliminating pathogenic factors, conventional decoctions have problems such as cumbersome decocting and bitter taste, and the internal administration of some traditional Chinese medicines containing toxic components may cause patients' concerns about safety.

[0003] The disclosure of the above background art content is only used to assist in understanding the concept and technical solution of the present invention, and it does not necessarily belong to the prior art of this patent application. Without clear evidence indicating that the above content was publicly available on the filing date of this patent application, the above background art should not be used to evaluate the novelty and inventiveness of this application. Summary of the Invention

[0004] This application provides a tablet for hot compress treatment of influenza and its preparation method, which can treat influenza and the sequelae of COVID-19.

[0005] To achieve the above object, the embodiments of this application disclose the following technical solutions:

[0006] In the first aspect, the embodiments of this application provide a tablet for hot compress treatment of influenza, which is made of the following components in parts by weight: 5 - 15 parts of Bupleuri Radix, 5 - 15 parts of Codonopsis Pilosulae Radix, 5 - 15 parts of Angelicae Sinensis Radix, 3 - 13 parts of Lonicerae Japonicae Flos, 7 - 17 parts of Forsythiae Fructus, 3 - 13 parts of Prunellae Spica, 5 - 15 parts of Coptidis Rhizoma, 5 - 15 parts of Phellodendri Chinensis Cortex, 3 - 13 parts of Carthami Flos.

[0007] In some possible implementation manners, the tablet is made of the following components in parts by weight: 10 parts of Bupleuri Radix, 10 parts of Codonopsis Pilosulae Radix, 10 parts of Angelicae Sinensis Radix, 8 parts of Lonicerae Japonicae Flos, 12 parts of Forsythiae Fructus, 8 parts of Prunellae Spica, 10 parts of Coptidis Rhizoma, 10 parts of Phellodendri Chinensis Cortex, 8 parts of Carthami Flos.

[0008] In the second aspect, the embodiments of this application provide a preparation method of a tablet for hot compress treatment of influenza, including the following steps:

[0009] (a) Pick fresh raw materials and wash to remove impurities;

[0010] (b) Place the raw materials in a cool and ventilated place to naturally dry until the water content ≤ 10%;

[0011] (c) Crush the dried raw materials and mix them according to the ratio of the traditional Chinese medicine tablets for hot compress treatment described in any technical solution of the first aspect to obtain a uniform powder;

[0012] (d) Press the mixed powder into tablets for external application.

[0013] One or more technical solutions provided in the first aspect in the embodiments of the present application have at least the following technical effects or advantages:

[0014] In the formula, Bupleurum chinense DC. dispels the pathogenic factors in the half-exterior and half-interior, and forms a situation of supplementing and purging when combined with Codonopsis pilosula (Franch.) Nannf. and Angelica sinensis (Oliv.) Diels. Codonopsis pilosula (Franch.) Nannf. supplements the middle-jiao and replenishes qi to strengthen the foundation, and Angelica sinensis (Oliv.) Diels promotes blood circulation and nourishes blood. The two assist the healthy qi to resist exogenous pathogenic factors, constituting the core framework of "strengthening the healthy qi and eliminating pathogenic factors". Four bitter-cold herbs, Lonicera japonica Thunb., Forsythia suspensa (Thunb.) Vahl, Coptis chinensis Franch., and Phellodendron amurense Rupr., form a medicinal power cluster for clearing heat and detoxifying. Among them, Lonicera japonica Thunb. penetrates heat and reaches the surface, Forsythia suspensa (Thunb.) Vahl clears the heart and disperses nodules, Coptis chinensis Franch. purges heart fire, and Phellodendron amurense Rupr. eliminates dampness-heat in the lower jiao. The four work together to inhibit the endogenous heat toxin generated during the virus replication process, and at the same time reduce the edema of the respiratory mucosa through the anti-inflammatory effect, corresponding to the state of "residual toxin not cleared" such as persistent sore throat and low fever after influenza and COVID-19 infection. Prunella vulgaris L. soothes the liver and disperses nodules, assisting in resolving phlegm-fire stagnation and stasis. Combined with Carthamus tinctorius L., it promotes blood circulation and dredges collaterals, improves chest tightness and unsmooth expectoration caused by qi stagnation and blood stasis. The two jointly promote the metabolism of pathological products, reflecting the efficacy of "resolving phlegm". The administration method of external hot compress enables the drug to penetrate the muscle surface by means of the warm effect, not only playing a role in dispelling cold and dampness locally, but also enhancing the body's disease resistance through stimulating the body surface nerve-immune regulation network. Especially for the symptoms of cold-damp retention such as fear of cold, fatigue, and muscle soreness common in COVID-19 sequelae, it forms a two-way regulation mechanism of "dispelling exogenous pathogenic factors and supplementing healthy qi internally". The whole formula combines cold and warm herbs, and combines purging and tonifying. While clearing the residual pathological products of the virus, it repairs the disorder of the body's immune function, thereby systematically improving the post-infection syndrome.

[0015] In summary, the traditional Chinese medicine tablets achieve the treatment of influenza and COVID-19 sequelae through the synergistic effect of multiple components.

[0016] In addition, since the preparation method of the tablets for hot compress treatment of influenza provided in the embodiments of the present application includes the tablets for hot compress treatment of influenza described in any of the above technical solutions, the two can solve the same technical problems and achieve the same technical effects. Detailed implementation mode

[0017] Reference will now be made in detail to specific embodiments of the invention. While the invention is described in connection with these specific embodiments, it is to be understood that the invention is not intended to be limited to these specific embodiments. On the contrary, these embodiments are intended to cover alternatives, modifications, or equivalent embodiments that may be included within the spirit and scope of the invention as defined by the claims. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the invention. The invention may be practiced without some or all of these specific details. In other instances, well-known process operations have not been described in detail so as not to unnecessarily obscure the invention.

[0018] When used in connection with the terms "comprising," "method comprising," or similar language in this specification and the appended claims, the singular forms "a," "an," "the" include plural references unless the context clearly dictates otherwise. All technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, unless otherwise defined.

[0019] An embodiment of the present application provides a tablet for hot compress treatment of influenza. The tablet is made of the following components in parts by weight: 5 - 15 parts of Bupleurum chinense, 5 - 15 parts of Codonopsis pilosula, 5 - 15 parts of Angelica sinensis, 3 - 13 parts of Lonicera japonica, 7 - 17 parts of Forsythia suspensa, 3 - 13 parts of Prunella vulgaris, 5 - 15 parts of Coptis chinensis, 5 - 15 parts of Phellodendron amurense, and 3 - 13 parts of Carthamus tinctorius.

[0020] Preferably, the tablet is made of the following components in parts by weight: 10 parts of Bupleurum chinense, 10 parts of Codonopsis pilosula, 10 parts of Angelica sinensis, 8 parts of Lonicera japonica, 12 parts of Forsythia suspensa, 8 parts of Prunella vulgaris, 10 parts of Coptis chinensis, 10 parts of Phellodendron amurense, and 8 parts of Carthamus tinctorius.

[0021] An embodiment of the present application also provides a method for preparing a tablet for hot compress treatment of influenza, comprising the following steps:

[0022] (a) Picking fresh raw materials and washing to remove impurities;

[0023] (b) Placing the raw materials in a cool and ventilated place to naturally dry until the water content ≤ 10%;

[0024] (c) Crushing the dried raw materials and mixing them according to the ratio of the traditional Chinese medicine tablets for hot compress treatment described in any of the above technical solutions to obtain a uniform powder;

[0025] (d) Pressing the mixed powder into tablets for external application.

[0026] Example 1:

[0027] The formula of the tablet for hot compress treatment of influenza is as follows: 5 g of Bupleurum chinense, 5 g of Codonopsis pilosula, 5 g of Angelica sinensis, 3 g of Lonicera japonica, 7 g of Forsythia suspensa, 3 g of Prunella vulgaris, 5 g of Coptis chinensis, 5 g of Phellodendron amurense, and 3 g of Carthamus tinctorius.

[0028] Example 2:

[0029] The formula for the hot compress tablet for treating influenza is as follows: 10 g of Bupleurum chinense, 10 g of Codonopsis pilosula, 10 g of Angelica sinensis, 8 g of Lonicera japonica, 12 g of Forsythia suspensa, 8 g of Prunella vulgaris, 10 g of Coptis chinensis, 10 g of Phellodendron amurense, 8 g of Carthamus tinctorius.

[0030] Example 3:

[0031] The formula for the hot compress tablet for treating influenza is as follows: 15 g of Bupleurum chinense, 15 g of Codonopsis pilosula, 15 g of Angelica sinensis, 13 g of Lonicera japonica, 17 g of Forsythia suspensa, 13 g of Prunella vulgaris, 15 g of Coptis chinensis, 15 g of Phellodendron amurense, 13 g of Carthamus tinctorius.

[0032] It should be noted that the preparation methods adopted in each example are the same.

[0033] Finally, it should be stated that the above examples are only used to illustrate the technical solutions of the present invention and are not intended to limit them; although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that it is still possible to modify the specific implementation manners of the present invention or make equivalent replacements for some technical features. Without departing from the spirit of the technical solutions of the present invention, they should all be covered within the scope of the technical solutions claimed by the present invention.

Claims

1. A hot compress tablet for treating influenza, characterized in that, The tablet is made from the following components in parts by weight: 5 - 15 parts of Bupleuri Radix, 5 - 15 parts of Codonopsis Pilosulae Radix, 5 - 15 parts of Angelicae Sinensis Radix, 3 - 13 parts of Lonicerae Japonicae Flos, 7 - 17 parts of Forsythiae Fructus, 3 - 13 parts of Prunellae Spica, 5 - 15 parts of Coptidis Rhizoma, 5 - 15 parts of Phellodendri Chinensis Cortex, 3 - 13 parts of Carthami Flos.

2. The hot compress influenza treatment tablet according to claim 1, characterized in that, The tablet is made from the following components in parts by weight: 10 parts of Bupleuri Radix, 10 parts of Codonopsis Pilosulae Radix, 10 parts of Angelicae Sinensis Radix, 8 parts of Lonicerae Japonicae Flos, 12 parts of Forsythiae Fructus, 8 parts of Prunellae Spica, 10 parts of Coptidis Rhizoma, 10 parts of Phellodendri Chinensis Cortex, 8 parts of Carthami Flos.

3. A preparation method for a hot compress treatment influenza tablet, characterized in that, It includes the following steps: (a) Picking fresh raw materials and cleaning to remove impurities; (b) Placing the raw materials in a cool and ventilated place to naturally dry until the water content ≤ 10%; (c) Crushing the dried raw materials and mixing according to the ratio of the traditional Chinese medicine tablet for hot compress treatment described in Claim 1 or 2 to obtain a uniform powder; (d) Pressing the mixed powder into tablets for external application.