Chemotherapy drug infusion device for tumor patient

Abstract

The invention relates to the technical field of chemotherapeutic drug infusion devices, in particular to a chemotherapeutic drug infusion device for tumor patients, which comprises a container for containing liquid medicine, an infusion tube with a drip chamber, a gas suction pump, a controller and a flow sensor, a bottle stopper puncture outfit is arranged at one end of the infusion tube, and an injection needle is arranged at the other end of the infusion tube. A puncture needle capable of penetrating into a container is arranged on a connecting pipe at the output end of the gas suction pump, the flow sensor is installed on an infusion pipeline and used for monitoring the flow of liquid medicine on the infusion pipeline, the signal output end of the flow sensor is connected with the signal input end of the controller, and the output end of the controller is used for outputting control signals. The control signal is used for controlling the operation of the gas suction pump, the air pressure in the container is adjusted, so that the flow of the liquid medicine in the infusion tube is adjusted, and the flow of the liquid medicine in the infusion tube is kept stable by controlling the air pressure in the container.

Description

Technical Field

[0001] The present invention relates to the technical field of chemotherapy drug infusion devices, and in particular to a chemotherapy drug infusion device for tumor patients. Background Art

[0002] Existing infusion devices include a bottle stopper puncture device, an infusion tube, a drip chamber, a flow rate regulator, a liquid medicine filter, a venous needle or an injection needle, and an air filter. They mainly utilize gravitational potential energy and atmospheric pressure to enable the drug to enter the human vein. Considering the cost of the infusion device and the fact that the flow rate of the liquid medicine does not need to be precisely controlled (the size of the liquid medicine concentration will not cause damage to the human body), this kind of infusion device is often used to infuse the human body for common colds and fevers.

[0003] For the delivery of chemotherapy liquid medicine for existing tumor patients, in order to ensure the maximum therapeutic effect and avoid damage to the human body, it is necessary to precisely control the flow rate of the chemotherapy liquid medicine. If the flow rate is too slow, the drug may not reach the effective blood drug concentration, thus affecting the treatment effect. On the contrary, if the infusion speed is too fast, some drugs may reach too high a concentration in a short time, instead increasing the risk of adverse reactions. The adverse reactions are mainly manifested in two aspects. First, it has a strong stimulating effect on the blood vessel wall. If the infusion speed is too fast, it may increase the risk of drug leakage, thereby causing tissue damage. Second, some chemotherapy drugs are toxic to the heart and kidneys. If the infusion speed is improper, it may aggravate the damage of these organs. Therefore, strict control of the infusion speed is required for the chemotherapy drugs of tumor patients. There are also peristaltic infusion pumps with flow rate control on the existing market, but they have many disadvantages. First, during the process of delivering the liquid medicine, the hose is a key component for delivering the liquid. However, when the hose is used for a long time or when delivering corrosive or particulate-containing fluids, it is prone to wear and rupture. This not only increases the maintenance cost, but also may cause the medicine to leak out, pollute the on-site environment, and even affect the treatment effect of the patient. Second, the working principle of the peristaltic pump is to squeeze and release the hose through rollers to deliver the liquid. This working method will cause pulsation phenomenon during the liquid delivery process, that is, the liquid flow rate is not constant but shows periodic changes. This pulsation phenomenon may affect the continuity of the liquid, which may be an unfavorable factor for patients who require a stable flow rate input. In order to reduce the influence of the pulsation phenomenon, a damper is usually installed at the output port, but this will also increase the complexity and cost of the system. Third, the size is generally large, and the patient cannot move conveniently during the infusion process. Summary of the Invention

[0004] The present invention provides a chemotherapy drug infusion device for tumor patients, which can control the air pressure inside the storage container, thereby realizing the flow rate adjustment inside the infusion tube and maintaining the stability of the liquid medicine flow rate inside the infusion tube.

[0005] The technical problem solved by the present invention is achieved by the following technical solutions: The present invention provides a chemotherapy drug infusion device for tumor patients, including a container for holding liquid medicine, an infusion tube with a drip chamber, one end of the infusion tube has a bottle stopper puncture device, and the other end has an injection needle. It also includes a gas suction pump, a controller, and a flow sensor. A puncture needle that can penetrate into the interior of the container is provided on the connecting tube at the output end of the gas suction pump. The flow sensor is installed on the infusion pipeline to monitor the liquid medicine flow rate on the infusion pipeline. The signal output end of the flow sensor is connected to the signal input end of the controller to provide a flow signal inside the infusion tube to the controller. The output end of the controller is used to output a control signal, and the control signal is used to control the operation of the gas suction pump to adjust the air pressure inside the container, thereby adjusting the liquid medicine flow rate inside the infusion tube.

[0006] Preferably, the length of the puncture needle is not less than the length of the container.

[0007] Preferably, it further includes an ultrasonic bubble sensor for monitoring whether there are bubbles inside the infusion tube. The output end of the ultrasonic bubble sensor is connected to the input end of the controller. When the ultrasonic bubble sensor detects that there are bubbles inside the infusion tube, the controller controls the gas suction pump to work so that the air pressure inside the container is maintained in a state where the liquid medicine inside the infusion tube is stationary.

[0008] Preferably, it further includes an alarm device. The alarm device operates under the control of the controller. When the ultrasonic bubble sensor detects that there are bubbles inside the infusion tube, the controller controls the alarm device to work.

[0009] Preferably, the flow sensor is detachably connected to the infusion tube.

[0010] Preferably, an air filter tube is provided at the input end of the gas suction pump.

[0011] Preferably, the controller and the gas suction pump are of an integral structure. A clip is provided on the back of the controller. A rigid sleeve is integrally formed on the outside of the infusion tube corresponding to the clip. The controller and the gas suction pump are clamped on the rigid sleeve through the clip to achieve the stability of the controller and the gas suction pump.

[0012] Preferably, the clip is an L-shaped elastic clip. An opening part is provided at the free end of the L-shaped elastic clip, and an arc-shaped groove adapted to the rigid sleeve is provided at the clamping position of the L-shaped clip.

[0013] The beneficial effects of the present invention are as follows: By setting a gas suction pump to control the internal air pressure of the container containing the liquid medicine, the flow rate inside the infusion tube can be controlled, and compared with the traditional peristaltic infusion pump, the continuity of infusion is better and the cost is lower.

[0014] By setting a controller and a flow sensor to cooperate with the gas suction pump, a closed-loop control of the flow rate can be achieved. The flow sensor monitors the magnitude of the flow rate, and the controller adjusts the gas suction pump to work, thereby achieving precise control of the flow rate and ensuring a constant flow rate of the liquid medicine delivery. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following-described drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0016] Figure 1 Schematic diagram of the prior art one provided by the present invention; Figure 2 Schematic diagram of the prior art two provided by the present invention; Figure 3 First perspective three-dimensional schematic diagram provided by the present invention; Figure 4 Second perspective three-dimensional schematic diagram provided by the present invention; Figure 5 Provided by the present invention Figure 4 Enlarged structural schematic diagram of part A; Figure 6 Cross-sectional structural schematic diagram provided by the present invention; Figure 7 Structural schematic diagram of the separation of the flow sensor and the infusion tube provided by the present invention; Figure 8 Provided by the present invention Figure 7 Enlarged structural schematic diagram of part B; Figure 9 Structural schematic diagram of the controller, gas suction pump, flow sensor and ultrasonic bubble sensor provided by the present invention; Figure 10 For the present invention Figure 3 Enlarged structural schematic diagram of part C; Figure 11 Circuit control principle structural schematic diagram provided by the present invention.

[0017] In the figure, 1 is a container; 2 is an infusion tube; 201 is a break connection; 202 is a rigid sleeve; 3 is a drip chamber; 4 is an air filter; 5 is a flow rate regulator; 6 is an injection needle; 7 is a rotor; 8 is a housing; 9 is a connecting body; 10 is a roller; 11 is a gas suction pump; 12 is a connecting tube; 13 is a puncture needle; 14 is an air filter tube; 15 is a controller; 16 is a flow sensor; 1601 is a plug connector; 17 is an ultrasonic bubble sensor; 18 is a clip; 1801 is an opening part; 1802 is an arc-shaped groove; 19 is an alarm device; 20 is a bottle stopper puncturer. Detailed implementation manners

[0018] In order to make the technical means, creative features, achieved purposes and functions of the present invention easy to understand, the present invention will be further described below with reference to specific illustrations.

[0019] In order to enable those skilled in the art to know the inventive points of the present invention, first, the prior art related to the present invention will be introduced. Refer to Figure 1 A common infusion device includes a container 1 for containing a medicinal solution, a bottle stopper puncturer 20 for puncturing the bottle stopper of the container 1, an infusion tube 2, a drip chamber 3, a flow rate regulator 5, an injection needle 6 and an air filter 4. When in use, the bottle stopper puncturer 20 penetrates into the interior of the container 1, and then the container 1 is hung at a high place. The medicinal solution inside the container 1 falls due to gravitational potential energy and fills the entire infusion tube 2. The injection needle 6 is punctured into the blood vessel of the human body, and the infusion of the human body can be realized. The flow rate of the medicinal solution inside the infusion tube 2 is adjusted by the flow rate regulator 5 to control the infusion speed. During the process of the liquid level in the container 1 dropping, external air will enter the interior of the container 1 from the air filter 4 to supplement the air pressure inside the container 1, thereby realizing the entire infusion process. The defect of this method is that although the flow rate regulator 5 can adjust the flow rate of the medicinal solution inside the infusion tube 2, it cannot achieve precise control. It can only observe the dropping speed of the liquid drops inside the drip chamber 3 according to experience, so it cannot precisely control the blood drug concentration and achieve the best treatment effect. Refer to Figure 2The principle of the existing peristaltic infusion pump for infusion is that the rotor 7 of the motor drives the roller 10 through the connecting body 9 to squeeze the infusion tube 2 of the extrusion chamber (in the figure, the extrusion chamber is defined by the housing 8 and has an arc-shaped inner wall of the chamber to facilitate the infusion tube 2 to be attached in an arc shape). During the process of squeezing the infusion tube 2, the liquid inside the infusion tube 2 is pushed to move, realizing the delivery of the liquid medicine. The disadvantage of this method is that when the roller 10 squeezes the infusion tube 2, the liquid medicine inside the infusion tube 2 can be pushed out. However, when the roller 10 is separated from the infusion tube 2, the infusion tube 2 resumes its deformation and the infusion is interrupted at this time. Therefore, during the process of using the peristaltic infusion pump for infusion, the infusion flow rate generated has a pulsation phenomenon, that is, the flow rate is sometimes fast and sometimes slow. It is necessary to add a damper to slow down this pulsation phenomenon, which undoubtedly increases the cost consumption. Moreover, adding a damper can only slow down the fluctuation amplitude of the pulsation phenomenon, and still cannot completely avoid the problem of large fluctuation amplitude of the flow rate when it is sometimes fast and sometimes slow.

[0020] Based on the above problems, the present invention provides a chemotherapy drug infusion device for tumor patients. Its common point with the existing traditional infusion device is that, referring to Figures 3 - 10 , it also includes a container 1 for holding the liquid medicine, an infusion tube 2 with a drip chamber 3, and one end of the infusion tube 2 has a bottle stopper puncture device 20 and the other end has an injection needle 6. Its difference from the traditional infusion device is that it further includes a gas extraction pump. The output end of the gas extraction pump has a connecting pipe 12, and the output end of the connecting pipe 12 is provided with a puncture needle 13 that can penetrate into the container 1 through the bottle stopper of the container 1. When the puncture needle 13 penetrates into the inside of the container 1, the puncture needle 13 is above the liquid level of the liquid medicine. Therefore, the length of the puncture needle 13 should be not less than the length of the container 1. The chemotherapy drug infusion device for tumor patients also includes a flow sensor 16 for real-time monitoring of the liquid medicine flow rate inside the infusion tube 2, referring to Figure 5 and Figure 8, there is a break connection 201 on the infusion tube 2. Both ends of the flow sensor 16 have plug connectors 1601. The break connection 201 of the infusion tube 2 is connected to the plug connectors 1601 at both ends of the flow sensor 16. Preferably, a detachable plug-and-play connection is adopted (that is, the flow sensor 16 can be cleaned and reused after use. The plug-and-play connection can adopt the existing mature Luer connector connection method), so as to install the flow sensor 16 on the infusion path of the infusion tube 2. The flow sensor 16 can specifically adopt a magnetic induction flow sensor 16. Its main principle is to measure the liquid flow rate when a conductive liquid passes through a magnetic field by using the magnetic induction principle, and determine the flow rate by detecting the voltage or current signal in the liquid. It is an existing mature flow sensor 16 and will not be elaborated in detail here. Of course, other types of flow sensors 16 can also be adopted, such as turbine flow meters, differential pressure flow meters, etc. The signal output end of the flow sensor 16 is connected to the signal input end of the controller 15, and is used to provide the flow signal inside the infusion tube 2 to the controller 15. The gas suction pump 11 operates under the control of the controller 15. In the specific use process, after the puncture needle 13 is inserted into the container 1, the controller 15 can control the air pressure inside the container 1 by controlling the action (exhausting or inflating) of the gas suction pump 11, and the air pressure inside the container 1 is used as the driving force to control the infusion liquid to be transported into the infusion tube 2. As Figure 11 shown, when the flow sensor 16 detects that the current flow rate is slow, the controller 15 controls the gas suction pump 11 to accelerate the exhaust, so that the air pressure inside the container 1 increases, generating a greater driving force, accelerating the discharge of the infusion liquid inside the container 1 to increase the flow rate. When the flow sensor 16 detects that the current flow rate inside the infusion tube 2 is low, the controller 15 controls the gas suction pump 11 to reduce the exhaust rate or draw air, so that the air pressure inside the container 1 decreases, thereby reducing the flow rate inside the infusion tube 2.

[0021] Furthermore, in order to prevent air from entering the human body during the infusion process, a drip chamber 3 is also provided on the infusion tube 2 of the present invention. The difference between this drip chamber 3 and the conventional infusion device during the infusion process is that the conventional drip chamber 3 generally has air during use, while in the present invention, when the drip chamber 3 is in use, under normal conditions, the inside of the drip chamber 3 is filled with the infusion liquid. Only when the gas inside the container 1 enters the drip chamber 3 along the infusion tube 2 above the drip chamber 3, will there be a small amount of air inside the drip chamber 3. Therefore, during its use, it mainly plays the role of intercepting air (the diameter of the drip chamber 3 is larger than that of the infusion tube 2. When air enters, the air will accumulate at the upper part of the drip chamber 3).

[0022] Furthermore, as Figure 10 and Figure 11As shown in the figure, in order to further ensure that the air inside the container 1 does not enter the human blood vessels during the infusion process, the present invention also adds an ultrasonic bubble sensor 17 (which generally has an ultrasonic transmitter and a receiver, respectively located on both sides of the infusion hose to monitor the bubbles, that is, the transmission speed of ultrasonic waves in the liquid medicine is inconsistent with that in the air, and the detailed principle will not be elaborated here), to monitor the infusion tube 2 below the drip chamber 3. When there is air in the infusion tube 2 below the drip chamber 3, the ultrasonic bubble sensor 17 detects the presence of bubbles, and the controller 15 controls the gas suction pump 11 to perform an inhalation action, making the air pressure above the liquid medicine in the container 1 lower than the atmospheric pressure, thereby preventing the liquid medicine from continuing to be delivered and achieving the effect of stopping the infusion.

[0023] Furthermore, as Figure 10 and Figure 11 shown, the present invention is also provided with an alarm device, which is used to perform an alarm operation under the control of the controller 15 when there are bubbles inside the infusion tube 2, so as to prompt the personnel that there are bubbles inside the current infusion tube 2 and to process it in time.

[0024] Furthermore, as Figure 9 and Figure 10 shown, an air filter tube 14 is provided at the input end (the communication end with the atmosphere) of the gas suction pump. The air filter tube 14 can have the same structure as the air filter 4 of the traditional infusion device. Its main function is to keep the air entering the container 1 clean and avoid dust contamination of the medicine.

[0025] The difference between the present invention and the existing peristaltic infusion pump is that it mainly controls the flow rate inside the infusion tube 2 by controlling the air pressure inside the container 1. At the same time, as Figures 8 - 10 shown, the controller 15 and the gas suction pump of the present invention both have a smaller volume and are of an integrated structure, so that they can be fixed on the infusion tube 2, that is, the gas suction pump 11 and the controller 15 are integrated. A clip 18 is provided on the back of the controller 15, and a rigid sleeve 202 is integrally formed at the position on the infusion tube 2 corresponding to the clamping of the clip 18. By clamping the clip 18 on the rigid sleeve, the controller 15 and the gas suction pump 11 are firmly fixed on the infusion tube 2, so as to facilitate the personnel to hold it when moving (such as going to the toilet, etc.). The flow sensor 16 and the ultrasonic bubble sensor 17 can also be set into an integrated and compact structure to ensure that the overall size is small. The flow sensor 16 and the ultrasonic bubble sensor 17 are both connected to the controller 15 through wires. It should be further noted that the alarm device 19 can be an LED indicator or a speaker, and it is integrated with the controller 15.

[0026] Further, to facilitate the disassembly and assembly of the clamping piece 18 and the rigid sleeve 202, the clamping piece 18 is an L-shaped elastic clamping piece 18. An opening part 1801 is provided at the free end of the L-shaped elastic clamping piece 18, and an arc-shaped groove 1802 adapted to the rigid sleeve 202 is provided at the clamping position of the L-shaped clamping piece 18. The opening part 1801 facilitates the entry of the rigid sleeve 202 into the clamping position of the L-shaped clamping piece 18, and the arc-shaped groove 1802 can ensure the stability of the clamping position.

[0027] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.

Claims

1. An infusion device for chemotherapy drugs for tumor patients, comprising a container (1) for holding the liquid medicine, an infusion tube (2) having a drip chamber (3), one end of the infusion tube (2) having a spike (20) and the other end having an injection needle (6), characterized in that, It further includes a gas suction pump (11), a controller (15) and a flow sensor (16). A connecting pipe (12) at the output end of the gas suction pump (11) is provided with a puncture needle (13) that can penetrate into the interior of the container (1). The flow sensor (16) is installed on the infusion tube (2) path for monitoring the liquid medicine flow rate on the infusion tube (2) path. The signal output end of the flow sensor (16) is connected to the signal input end of the controller (15) for providing a flow signal inside the infusion tube (2) to the controller (15). The output end of the controller (15) is used to output a control signal, and the control signal is used to control the operation of the gas suction pump (11) to adjust the air pressure inside the container (1), thereby adjusting the liquid medicine flow rate inside the infusion tube (2).

2. The chemotherapy drug infusion device for tumor patients according to claim 1, characterized in that, The length of the puncture needle (13) is not less than the length of the container (1).

3. The chemotherapy drug infusion device for tumor patients according to claim 1, wherein It further includes an ultrasonic bubble sensor (17) for monitoring whether there are bubbles inside the infusion tube (2). The output end of the ultrasonic bubble sensor (17) is connected to the input end of the controller (15). When the ultrasonic bubble sensor (17) detects that there are bubbles inside the infusion tube (2), the controller (15) controls the gas suction pump (11) to work so that the air pressure inside the container (1) is maintained at a state where the liquid medicine inside the infusion tube (2) is stationary.

4. The chemotherapy drug infusion device for tumor patients according to claim 3, wherein It further includes an alarm device (19). The alarm device (19) operates under the control of the controller (15). When the ultrasonic bubble sensor (17) detects that there are bubbles inside the infusion tube (2), the controller (15) controls the alarm device (19) to work.

5. The chemotherapy drug infusion device for tumor patients according to claim 1, wherein, The flow sensor (16) is connected to the infusion tube (2) in a pluggable manner.

6. The chemotherapy drug infusion device for tumor patients according to claim 1, characterized in that, An air filter tube (14) is provided at the input end of the gas suction pump (11).

7. The chemotherapy drug infusion device for tumor patients according to claim 1, wherein The controller (15) and the gas suction pump (11) are of an integrated structure. A clip (18) is provided on the back of the controller (15). A rigid sleeve body (202) is integrally formed on the outside of the infusion tube (2) corresponding to the clip (18). The controller (15) and the gas suction pump (11) are clamped on the rigid sleeve body (202) through the clip (18) to achieve the stability of the controller (15) and the gas suction pump (11).

8. The chemotherapy drug infusion device for tumor patients according to claim 7, wherein, The clip (18) is an L-shaped elastic clip (18). An opening part (1801) is provided at the free end of the L-shaped elastic clip (18). An arc-shaped groove (1802) adapted to the rigid sleeve body (202) is provided at the clamping position of the L-shaped clip (18).

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