A quality detection device for producing guaifenesin bulk drug

Abstract

The application relates to a quality detection equipment for producing guaifenesin raw medicine, and relates to the technical field of medicine detection. The equipment comprises a detection tank, a detection disc is rotationally installed on the inner wall of the detection tank, a plurality of annular grooves are coaxially arranged on the upper end of the detection disc, the groove diameters of the annular grooves gradually increase from the center of the detection disc to the edge, and a driving assembly for driving the detection disc to rotate is arranged in the detection tank. A scraping strip is installed on the inner wall of the detection tank, the lower end surface of the scraping strip is in sliding abutment with the upper end surface of the detection disc, the scraping strip can push the object at the center of the detection disc to the edge of the detection disc when the detection disc rotates, a feeding assembly is used for conveying the raw medicine to the center of the upper end surface of the detection disc, and the output end of a shooting assembly is opposite to the upper end surface of the detection disc. The application can avoid the aggregation of powder particles during detection, thereby improving the detection precision of the detection equipment.

Description

Technical Field

[0001] This application relates to the technical field of pharmaceutical testing, and in particular to a quality testing device for the production of guaiacol glycerol ether raw material. Background Technology

[0002] Guaifenesin active pharmaceutical ingredient (API) is the active pharmaceutical ingredient used in the production of guaifenesin formulations. It typically exists as a white or off-white crystalline powder and has a well-defined chemical structure, pharmacological activity, and quality standards. Its manufacturing process, purification methods, and storage conditions must all comply with Good Manufacturing Practices (GMP) requirements to ensure the safety and efficacy of the drug.

[0003] Since guaiacol glycerol ether raw material is needed for the production of subsequent formulations and tablets, the particle size of guaiacol glycerol ether raw material needs to be detected during the production process. In existing technology, high-definition cameras and airflow dispersion technology are generally combined. The shear force generated by the airflow disperses the powder particles in a specific cavity. Due to the weight of the powder particles themselves and the buoyancy of the airflow, the powder particles reach a relatively balanced state and are suspended in the specific cavity, so that the high-definition camera can capture and inspect each powder particle as much as possible.

[0004] However, in the above technology, since the volume of each powder particle is different, the gravity of each powder particle is different, and therefore the suspension height of each powder particle in the cavity is also different. Furthermore, since most of the powder particles in each batch of test objects are of the size that meets the quality inspection requirements (i.e., medium size), while large-volume powder particles and a small portion of small-volume powder particles are only a relatively small part, most of the particles will gather in the middle of the cavity, which will affect the shooting of the high-definition camera and reduce the detection accuracy of the equipment. Summary of the Invention

[0005] The purpose of this application is to provide a quality testing device for the production of guaiacol glycerol ether raw material, which can minimize the aggregation of powder particles during testing, thereby improving the testing accuracy of the device.

[0006] The quality testing equipment for producing guaiacol glycerol ether raw material provided in this application adopts the following technical solution:

[0007] Testing container;

[0008] The detection disc is rotatably mounted on the inner wall of the detection tank. Multiple annular grooves are coaxially formed on the upper end of the detection disc. The diameter of the multiple annular grooves increases sequentially from the center of the detection disc to the edge. The detection tank is also equipped with a drive assembly for driving the detection disc to rotate.

[0009] A scraper is installed on the inner wall of the detection tank, and the lower end face of the scraper slides against the upper end face of the detection disk. When the detection disk rotates, the scraper can push the object at the center of the detection disk to the edge of the detection disk.

[0010] A feeding assembly, installed on the testing tank, is used to transport the raw material to the center of the upper surface of the testing tray;

[0011] The imaging component is installed on the inner wall of the detection tank, with its output end facing the upper surface of the detection plate.

[0012] Optionally, multiple annular grooves are classified into three types: small, medium, and large, according to their groove diameter. The number of annular grooves of each type decreases sequentially from small to large groove diameter.

[0013] Optionally, multiple scrapers are provided, and the multiple scrapers are evenly spaced around the axis of the detection disk. The ends of the multiple scrapers that are close to each other form a closed circle. The feeding component divides the raw material into multiple portions and transports them to the space between two adjacent scrapers.

[0014] Optionally, each of the scraper blades has a rubber pad on its lower end face, and the rubber pad slides against the upper end face of the detection disc.

[0015] Optionally, the detection tank is also equipped with a recycling component, which includes a recycling tank and a waste tank. Each scraper has three recycling ports at its lower end, which correspond to annular grooves of large, medium, and small diameters, respectively. A recycling pipe connects the recycling port corresponding to the medium diameter annular groove to the recycling tank, and a recycling pipe connects the recycling port corresponding to the large and small diameter annular grooves to the waste tank. Both the waste tank and the recycling tank are equipped with air pumps.

[0016] Optionally, the feeding assembly includes a feeding pipe, which is coaxially mounted on the detection tank. One end of the feeding pipe is located outside the detection tank, and the other end of the feeding pipe is coaxially located above the detection disc. Multiple guide pipes are provided on the peripheral wall of the feeding pipe, and the end of each guide pipe away from the feeding pipe is directly opposite the gap between two scrapers.

[0017] Optionally, a guide block is provided on the inner wall of the feeding pipe. The guide block is cone-shaped and has multiple concave surfaces on its inclined surface, with each concave surface corresponding to a different feeding pipe.

[0018] Optionally, the feed pipe is also equipped with an electric valve, the valve port of which is funnel-shaped and is coaxially arranged with the guide block.

[0019] In summary, this application includes at least one of the following beneficial technical effects:

[0020] 1. The multiple annular grooves and scraper in this application allow the raw material powder to be distributed according to its size into its corresponding annular grooves. Powder particles in the large-diameter and small-diameter annular grooves do not meet the requirements, while the powder particles in the medium-diameter annular grooves do meet the requirements. Therefore, when the imaging component transmits the image information to the control center, the control center does not need to analyze and calculate the particle size in the annular grooves, but only needs to detect the appearance shape of the powder particles. This greatly reduces the computing power of the control center, thereby improving the analysis efficiency of the control center and thus improving the detection efficiency. At the same time, since the diameter of the annular groove corresponds to the particle volume, the powder particles in the annular grooves will not be stacked vertically. Each particle will be laid flat on a plane, so that the imaging component can capture the appearance of each particle as much as possible and can detect the number of large and small particles in each sample, thereby greatly improving the detection accuracy of the detection equipment.

[0021] 2. The number of small-diameter annular grooves has been increased, which allows the originally accumulated powder to pass through the small-diameter annular grooves multiple times during the sliding process. This helps to prevent small-volume powder particles from being supported by medium or large-volume particles as they pass through the small-diameter annular grooves, thus preventing small-volume powder particles from entering the wrong annular grooves and causing inaccurate test data.

[0022] 3. The use of multiple scraper strips serves two main purposes. First, due to deformation or other factors, gaps may form between the scraper strip and the upper surface of the detection disc. This could cause some particles to remain on the upper surface of the detection disc and fail to enter the annular groove, leading to inaccurate detection data. Multiple scraper strips minimize this issue, further improving the accuracy of the detection data. Second, the multiple scraper strips can form relatively independent spaces, thus distributing the sample from the feeding assembly more evenly. This further minimizes the accumulation of powder particles and reduces the likelihood of them entering the wrong annular groove, thereby further improving the detection accuracy of the equipment.

[0023] 4. The rubber pad serves two purposes. First, it reduces the gap between the scraper and the upper surface of the detection disc, minimizing the possibility of particles being left on the upper surface of the detection disc and thus improving the accuracy of the detection data. Second, the rubber pad itself has a certain degree of elasticity, and its deformed portion can extend into the annular groove. Furthermore, the rubber pad increases the friction between the scraper and the powder particles. Therefore, when the rubber pad comes into contact with the powder particles in the annular groove, the friction causes the powder particles to tumble, facilitating multi-angle imaging of the powder particles by the imaging component. This allows the control center to obtain the most complete appearance and shape data of the powder particles, further improving the detection accuracy of the equipment. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the overall structure of an embodiment of this application;

[0025] Figure 2 This is a schematic diagram of the structure of the imaging component in an embodiment of this application;

[0026] Figure 3 This is a schematic diagram of the structure of the recycling component in an embodiment of this application;

[0027] Figure 4 This is a schematic diagram of the scraper structure in the embodiment of the application;

[0028] Figure 5 This is a schematic diagram of the combination of the scraper and the detection disc in an embodiment of this application;

[0029] Figure 6 This is a schematic diagram of the structure of the electric valve and the flow guide block in the embodiments of this application;

[0030] Figure 7 This is a schematic diagram of the combination of the recycling component and the scraper in an embodiment of this application;

[0031] Figure 8 yes Figure 7 Enlarged view of point A in the middle;

[0032] In the diagram, 1. Detection tank; 11. Column; 2. Detection disc; 21. Annular groove; 211. Small diameter annular groove; 212. Medium diameter annular groove; 213. Large diameter annular groove; 3. Drive assembly; 4. Scraper; 41. Rubber pad; 42. Recovery port; 43. Connecting rod; 5. Feeding assembly; 51. Feeding pipe; 52. Guide pipe; 53. Guide block; 531. Concave surface; 54. Electric valve; 6. Imaging assembly; 7. Recovery assembly; 71. Recovery tank; 72. Waste tank; 73. Recovery pipe. Detailed Implementation

[0033] The following is in conjunction with the appendix Figure 1-8This application will be described in further detail below.

[0034] A quality testing device for the production of guaiac glycerol ether raw material, referring to Figure 1 , Figure 2 and Figure 3 It includes a detection tank 1, a detection plate 2, a scraper 4, a feeding assembly 5, and a shooting assembly 6.

[0035] In this embodiment, the detection container 1 is cylindrical and made of transparent material so that staff can observe the situation inside the detection container 1 in real time.

[0036] A column 11 is coaxially mounted at the bottom of the testing tank 1. A testing disk 2 is coaxially rotatably mounted on the upper end face of the column 11. A drive assembly 3 for driving the testing disk 2 to rotate around its own axis is provided between the column 11 and the testing disk 2. In this embodiment, the drive assembly 3 is a rotating motor. A groove for accommodating the rotating motor is opened on the upper end face of the column 11. The output shaft of the rotating motor is coaxially fixedly connected to the bottom of the testing disk 2. Multiple annular grooves 21 are coaxially opened on the upper end face of the testing disk 2. In this embodiment, the upper end face of the testing disk 2 and the groove walls of the annular grooves 21 are both smooth metal surfaces to avoid powder adhering to the surface of the testing disk 2. The multiple annular grooves 21 are arranged on the upper end face of the testing disk 2 in a manner similar to annual rings. The groove diameter of the multiple annular grooves 21 increases sequentially from the center of the testing disk 2 to the edge of the testing disk 2. That is, the groove diameter of the annular groove 21 closer to the center of the testing disk 2 is smaller, and the groove diameter of the annular groove 21 closer to the edge of the testing disk 2 is larger.

[0037] In this embodiment, the scraper 4 is fixedly installed on the inner wall of the detection tank 1 via the connecting rod 43. The lower end face of the scraper 4 slides against the upper end face of the detection disk 2. Furthermore, the scraper 4 is not positioned along the center of the upper end face of the detection disk 2; that is, the scraper 4 is not aligned with the radius of the upper end face of the detection disk 2. Therefore, when the detection disk 2 rotates, the scraper 4 can push the object near the center of the upper end face of the detection disk 2 towards the edge of the upper end face (in conjunction with...). Figure 4 ).

[0038] In this embodiment, the feeding component 5 is fixedly installed on the detection tank 1, and the feeding component 5 is used to transport the raw material outside the detection tank 1 from the top of the detection tank 1 to the inside of the detection tank, until the center of the upper surface of the detection plate 2. In this embodiment, the imaging component 6 is set as two high-definition cameras. Both high-definition cameras are fixedly installed on the inner wall of the upper end of the detection tank 1, and the two high-definition cameras are arranged opposite each other on both sides of the axis of the detection plate. The output ends of the two high-definition cameras face the upper surface of the detection plate 2.

[0039] When testing of guaiacol ether raw material is required, the sample is transported from the top of the testing tank 1 to the inside of the testing tank 1 via the feeding assembly 5, until it reaches the center of the upper surface of the testing disc 2. Then, the rotating motor is started, and the rotating motor drives the testing disc 2 to rotate counterclockwise (according to...). Figure 4 (As shown in the counterclockwise direction), since the scraper 4 is relatively stationary and slides against the upper surface of the detection disk 2, the detection disk 2 and the scraper 4 will slide relative to each other. At this time, the scraper 4, which slides against the upper surface of the detection disk 2, pushes the raw material sample at the center of the upper surface of the detection disk 2 to move. Since the layout direction of the scraper 4 does not pass through the center of the upper surface of the detection disk 2, the scraper 4 will exert a pushing force on the raw material powder particles on the upper surface of the detection disk 2 perpendicular to the layout direction of the scraper 4. This pushing force can be decomposed into two forces, one of which is perpendicular to the radius of the detection disk 2 and the direction of action of the force is counterclockwise (according to...). Figure 4(The force shown is counterclockwise). The direction of another force coincides with the radius of the detection disk 2, and the direction of the force extends from the center of the detection disk 2 to the edge of the detection disk 2. Therefore, when the scraper 4 pushes the raw material on the detection disk 2 to move, the raw material on the detection disk 2 is pushed from the center of the upper end face of the detection disk 2 to the edge. When the raw material moves, it will pass through multiple annular grooves 21 on the detection disk 2. Since the groove diameter of the annular groove 21 is smaller closer to the center of the detection disk 2, the raw material will first encounter the annular groove 21 with the smaller groove diameter during the movement. At this time, the relatively small raw material powder particles in the sample enter the groove with the smaller diameter. In the smaller annular groove 21, larger powder particles cannot enter because they cannot fit into the smaller annular groove 21. Instead, they are pushed by the scraper 4 along the edge of the detection disk 2 until the powder particles in the raw material sample pass through the annular groove 21 corresponding to their own volume. At this point, the raw material powder particles will enter the annular groove 21. Therefore, in this embodiment, the multiple annular grooves 21 with different diameters on the detection disk 2 can classify the raw material powder particles in the sample according to their size. When the imaging component 6 transmits the image of the upper surface of the detection disk 2 to the control center, the control center only needs to roughly calculate the powder particles in the annular grooves 21 that do not meet or meet the requirements. The number ratio of particles is sufficient; there is no need to calculate the volume of powder particles within the annular groove 21. The control center then calculates the appearance shape of the powder particles within the annular groove 21 that meets the requirements, and then calculates the number of powder particles within the annular groove 21 that meet the appearance shape requirements. This yields the most complete test data for the sample. Compared to the prior art, which relies on the imaging component 6 and the control center to perform individual appearance inspection and volume measurement for each particle, the control center in this embodiment requires less computation. Therefore, the calculation speed of the control center in this embodiment is faster, thus accelerating the detection efficiency of the device. Furthermore, in this embodiment… The diameter of the annular groove 21 corresponds to the particle volume, so the powder particles in the annular groove 21 will not be stacked vertically. Each particle will be laid flat on a plane, and there will be no mutual obstruction between particles. This allows the imaging component 6 to capture the appearance of each particle as much as possible, and to detect the number of large and small particles in each sample relatively accurately, thereby obtaining more complete and accurate detection data. Compared with the combination of imaging component 6 and airflow dispersion technology in the prior art, the device in this application is less likely to have mutual obstruction between particles. Therefore, this application has higher detection accuracy.

[0040] Specifically, in this embodiment, the multiple annular grooves 21 are classified into three types according to their diameter: small-diameter annular grooves 211, medium-diameter annular grooves 212, and large-diameter annular grooves 213. There are four small-diameter annular grooves 211, four medium-diameter annular grooves 212, and three large-diameter annular grooves 213. The small-diameter annular grooves 211 are closest to the center of the upper surface of the detection disk 2, while the large-diameter annular grooves 213 are furthest from the center of the upper surface of the detection disk 2. The medium-diameter annular grooves 212 are located between the large-diameter annular grooves 213 and the small-diameter annular grooves 211. Although in practice, the number of large and small volume powder particles in each sample is relatively small, while the number of medium volume powder particles is relatively large, this embodiment sets the number of medium-diameter annular grooves 212 and the number of small-diameter annular grooves 211 to be the same. The main reason for this is that the small-diameter annular grooves 211 are smaller than the large-diameter annular grooves 211. The annular groove 211 is closer to the center of the detection disk 2, so its radius is smaller, meaning its length is shorter and its total volume is also smaller. Therefore, to ensure that the annular groove 211 can accommodate all small-volume powder particles, the total volume of the annular groove 211 needs to be increased, i.e., the number of annular grooves 211 needs to be increased. In addition, increasing the number of annular grooves 211 increases the number of layers. Therefore, when the scraper 4 pushes the sample powder particles from the center of the detection disk 2 to the edge, the sample powder particles can pass through the annular grooves 211 more times, thus minimizing the possibility of small-volume powder particles being wrapped by large and medium-volume powder particles when passing through the annular grooves 211. This improves the classification ability of the annular groove 211 and further ensures the accuracy of the data and the detection precision of the device.

[0041] Among them, reference Figure 4 and Figure 5 In this embodiment, multiple scraper strips 4 are provided, specifically six scraper strips 4. These six scraper strips 4 are evenly spaced around the axis of the detection disk 2, and their closest ends form a closed circle. The feeding assembly 5 can divide the raw drug powder particles into six portions, which are then transported to the gaps between adjacent scraper strips 4. The feeding assembly 5 divides the raw drug powder particles into six portions, and then the six scraper strips 4 push these six portions of raw drug powder particles respectively. The possibility of accumulation is lower when six portions are combined compared to one portion. Therefore, when the scraper strips 4 push the corresponding portion of powder particles from the center of the detection disk 2 to the edge, smaller powder particles are less likely to be encased by larger or medium-sized particles due to accumulation and pass through the small-diameter annular groove 21, thereby further ensuring the accuracy of the data and the detection precision of the device.

[0042] Secondly, in this embodiment, the lower end face of each of the six scraper strips 4 is provided with a rubber pad 41 (in conjunction with...). Figure 7 and Figure 8 The rubber pad 41 slides against the upper surface of the detection disk 2. Due to the elasticity of the rubber pad 41, compared to the direct contact between the scraper 4 and the detection disk 2, it significantly reduces the friction between them, thus reducing wear and extending the equipment's lifespan. Simultaneously, the elasticity of the rubber pad 41 allows it to fit more tightly against the upper surface of the detection disk 2, greatly reducing the gap between the scraper 4 and the detection disk 2. This prevents powder particles from passing through the gap and entering the annular groove 21, further ensuring the accuracy of the detection data and improving the equipment's detection precision. Furthermore, due to its elasticity, the rubber pad 41 can undergo some elastic deformation, allowing some... The rubber pad 41 can extend into the annular groove 21. When part of the rubber pad 41 extends into the annular groove 21, the rubber pad 41 comes into contact with the powder particles in the annular groove 21. Since the friction between the rubber pad 41 and the powder particles is greater than the friction between the powder particles and the groove wall of the annular groove 21, when the rubber pad 41 comes into contact with the powder particles in the annular groove 21, the rubber pad 41 will move the powder particles in the annular groove 21. After the powder particles in the annular groove 21 are moved, the contact part between the powder particles and the groove wall of the annular groove 21 is moved to face the groove opening of the annular groove 21. This makes it easier for the imaging component 6 to take pictures of the powder particles in the annular groove 21 from multiple angles, so that the control center can obtain the most complete appearance shape data of the powder particles, thereby further improving the detection accuracy of the detection equipment.

[0043] Additionally, refer to Figure 5 and Figure 6 In this embodiment, the feeding assembly 5 includes a feeding pipe 51, which is coaxially fixedly installed on the upper end face of the detection tank 1. One end of the feeding pipe 51 is located outside the detection tank 1, and the other end is located inside the detection tube and coaxially located above the detection disc 2. Six guide pipes 52 are provided on the outer peripheral wall of the feeding pipe 51, and the six guide pipes 52 correspond one-to-one with six scraper strips 4. The original ends of the six guide pipes 52 are directly opposite the gaps between two adjacent scraper strips 4. The connecting rods 43 connected to the scraper strips 4 are fixedly installed on the outer peripheral wall of the feeding pipe 51. When the raw material sample powder particles are poured from the upper end of the feeding pipe 51, the raw material sample powder particles are automatically divided into six parts, and then fall from the six guide pipes 52 into the gaps between two adjacent scraper strips 4, thereby achieving relatively uniform distribution of the raw material sample powder particles.

[0044] In this embodiment, a guide block 53 is coaxially arranged on the inner wall of the feeding tube 51. The guide block 53 in this embodiment is set as a pointed cone shape, and six concave surfaces 531 are opened on the inclined surface of the guide block 53. The six concave surfaces 531 correspond one-to-one with the six guide tubes 52. When the sample powder particles in the feeding tube 51 fall onto the guide block 53, since the upper end of the guide block 53 is pointed, the sample powder particles in the feeding tube 51 fall onto the inclined surface of the guide block 53. Then, the arrangement of the six concave surfaces 531 can more evenly divide the sample powder particles in the feeding tube 51, thereby making the number of sample powder particles flowing out from the six guide tubes 52 more even.

[0045] Meanwhile, an electric valve 54 is also installed on the inner wall of the feeding pipe 51. The valve port of the electric valve 54 is funnel-shaped and is coaxially arranged with the guide block 53. On the one hand, the electric valve 54 can accurately control the amount of sample released each time, thereby avoiding the situation where too much sample falls onto the detection plate 2, which would lead to a decrease in detection accuracy, and also avoiding the situation where too little sample falls onto the detection plate 2, which would lead to a decrease in detection efficiency. On the other hand, the funnel-shaped valve port of the electric valve 54 and its coaxial arrangement with the guide block 53 can ensure that the sample falls as much as possible at the tip of the guide block 53, so that the sample can be more evenly distributed into the six concave surfaces 531. This makes the number of sample powder particles flowing out of the six feed pipes 52 more uniform, avoids sample accumulation, and improves the detection accuracy of the device.

[0046] Finally, refer to Figure 4 , Figure 5 and Figure 7In this embodiment, the detection tank 1 is also equipped with a recycling component 7, which includes a recycling tank 71 and a waste tank 72. Two recycling tanks 71 are provided in this embodiment, fixedly installed on the inner wall of the detection tank 1, and arranged opposite each other on both sides of the feed pipe 51. Each scraper 4 has three recycling ports 42 at its lower end. The recycling port 42 closest to the center of the detection disc 2 on the scraper 4 corresponds to the small-diameter annular groove 211, the recycling port 42 furthest from the center of the detection disc 2 on the scraper 4 corresponds to the large-diameter annular groove 213, and the recycling port 42 in the middle of the scraper 4 corresponds to the medium-diameter annular groove 212. A recycling pipe 73 is provided between the three recycling ports 42 on the three scraper 4 corresponding to the medium-diameter annular groove 212 and the recycling tank 71. This recycling pipe 73 is a four-way pipe. Four waste tanks 72 are provided. The sample is fixedly installed on the inner wall of the testing tank 1, and the four waste tanks 72 are arranged in pairs. The two groups of waste tanks 72 are arranged opposite each other on both sides of the feeding pipe 51. The three scrapers 4 are connected to the recovery port 42 corresponding to the large diameter annular groove 21 and one of the waste tanks 72 in the left group of waste tanks 72 by a recovery pipe 73. The three scrapers 4 are connected to the recovery port 42 corresponding to the small diameter annular groove 21 and another waste tank 72 in the left group of waste tanks 72 by a recovery pipe 73. The structure between the right group of waste tanks 72 and the other three scrapers 4 is the same as the structure of the left group of waste tanks 72. All recovery tanks 71 are four-way pipes. Both the waste tanks 72 and the recovery tanks 71 are equipped with air pumps, which are connected to the recovery pipes 73.

[0047] After the imaging component 6 and the control center have finished detecting all the particles in the annular grooves 21, the rotating motor continues to drive the detection disc 2 to rotate. Then, the control center will start the air pumps on the waste tank 72 and the recycling tank 71. The waste tank 72 will absorb the powder particles in the large and small diameter annular grooves 21. The powder particles in the waste tank 72 are defective products and can be recycled and remanufactured, while the powder particles in the recycling tank 71 are qualified products and are placed in the qualified product pile for packaging and sale. This greatly reduces the waste of raw materials and improves the utilization rate of resources. At the same time, the recycling component 7 also cleans the sample on the detection disc 2 so that the detection device can detect the next batch of samples.

[0048] It should be noted that the detection device in this embodiment can be used to test multiple samples in a laboratory, or it can be installed on the production line of a manufacturing plant to continuously sample and test the raw materials on the production line. It only requires adding a suction tube and a suction pump to the upper port of the feeding pipe 51, and then using the suction pump and suction tube to intermittently extract the raw material powder on the production line and then test it. After the test is completed, the recovery component 7 can classify and recover the tested samples located on the detection tray 2 so that the test can be continued next time, thereby realizing continuous testing. Therefore, the detection device in this embodiment also has good practicality in actual situations.

[0049] The working principle of a quality testing device for producing guaiacol ether raw material in this embodiment is as follows: When testing the guaiacol ether raw material is required, the raw material sample is poured in through the opening at the top of the feeding pipe. Then, the electric valve is opened, and the raw material sample flows out from the bottom of the funnel-shaped electric valve and falls onto the tip of the guide block. The raw material sample on the tip of the guide block slides down the sides of the guide block and slides into the six concave surfaces on the guide block. At this time, all the raw material samples are divided into six parts. Then, the raw material samples in the concave surfaces flow through the corresponding feed pipe to the gap between two adjacent scrapers and are located at the center of the upper surface of the detection plate. The rotating motor is started, and the rotating motor drives the detection plate to rotate. The detection plate and the scrapers are relatively displaced. The scrapers gradually push the raw material sample at the center of the detection plate to the edge of the detection plate. During the movement of the raw material sample on the detection plate, the raw material will pass through the small diameter annular groove, the medium diameter annular groove, and the large diameter annular groove in sequence. Different volumes of powder in the raw material... The final particles fall into the corresponding annular grooves according to their size, thus classifying the powder particles. Based on the photos taken by the imaging component, the number of powder particles in each annular groove can be calculated. During the process of the scraper pushing the raw material sample on the detection plate, the rubber pad at the bottom of the scraper can also move the powder particles in the annular grooves. After being moved, the part of the powder particles in the annular groove that is in contact with the groove wall will be moved to the groove opening directly opposite the groove. This allows the imaging component to take pictures of the powder particles in the annular grooves from multiple angles, so that the control center can obtain the most complete appearance shape data of the powder particles. After the detection is completed, the air pump is started. The powder particles in the small-diameter and large-diameter annular grooves are sucked into the waste tank, while the powder particles in the medium-diameter annular grooves are sucked into the recovery tank. Therefore, the recovery component performs different recovery treatments for different types of powder particles, and also cleans the powder particles on the detection plate so that the detection equipment can detect the next batch of raw material samples.

[0050] The embodiments described in this specific implementation are preferred embodiments of this application and are not intended to limit the scope of protection of this application. Identical components are represented by the same reference numerals. Therefore, all equivalent changes made to the structure, shape, and principle of this application should be covered within the scope of protection of this application.

Claims

1. A quality detection apparatus for producing guaifenesin bulk drug, characterized by, The utility model relates to a kind of detection device for raw material medicine, including: Detection tank (1); Detection disc (2) is rotationally installed on the inner wall of the detection tank (1), a plurality of annular grooves (21) are coaxially provided on the upper end of the detection disc (2), the groove diameter of the plurality of annular grooves (21) increases gradually from the center to the edge of the detection disc (2), and a driving assembly (3) for driving the rotation of the detection disc (2) is further arranged in the detection tank (1); Scraping strip (4) is installed on the inner wall of the detection tank (1), and the lower end surface of the scraping strip (4) is in sliding abutment with the upper end surface of the detection disc (2), after the detection disc (2) rotates, the scraping strip (4) can push the object at the center of the detection disc (2) to the edge of the detection disc (2); Feeding assembly (5) is installed on the detection tank (1), and the feeding assembly (5) is used to transport raw medicine to the center of the upper end surface of the detection disc (2); Photographing assembly (6) is installed on the inner wall of the detection tank (1), and the output end of the photographing assembly (6) is opposite to the upper end surface of the detection disc (2).

2. The quality detection device for producing guaifenesin raw material medicine according to claim 1, characterized in that, The plurality of annular grooves (21) are classified into three types of small, medium and large annular grooves (21) according to the size of the groove diameter, and the number of each type of annular groove (21) decreases gradually from small to large according to the groove diameter.

3. The quality detection device for producing guaifenesin raw material medicine according to claim 2, characterized in that, The scraping strip (4) is provided with a plurality of scraping strips (4), and the plurality of scraping strips (4) are uniformly and interval arranged around the axis of the detection disc (2), and the ends of the plurality of scraping strips (4) close to each other are enclosed into a closed circle, the feeding assembly (5) divides the raw medicine into multiple parts, and respectively transports to between adjacent two scraping strips (4).

4. The quality detection device for producing guaifenesin raw material medicine according to claim 3, characterized in that, The lower end surface of each scraping strip (4) is provided with a rubber pad (41), and the rubber pad (41) is in sliding abutment with the upper end surface of the detection disc (2).

5. The quality detection device for producing guaifenesin raw material medicine according to claim 3, characterized in that, The detection tank (1) is further provided with a recycling assembly (7), the recycling assembly (7) comprises a recycling tank (71) and a waste tank (72), the lower end of each scraping strip (4) is provided with three recycling ports (42), the three recycling ports (42) correspond to the annular grooves (21) with large, medium and small diameters respectively, the recycling port (42) corresponding to the annular groove (21) with medium diameter is communicated with the recycling tank (71) through a recycling pipe (73), the recycling port (42) corresponding to the annular grooves (21) with large and small diameters is communicated with the waste tank (72) through a recycling pipe (73), and the waste tank (72) and the recycling tank (71) are provided with an air pump.

6. The quality detection device for producing guaifenesin raw material medicine according to claim 3, characterized in that, The feeding assembly (5) comprises a feeding pipe (51), the feeding pipe (51) is coaxially installed on the detection tank (1), one end of the feeding pipe (51) is located outside the detection tank (1), the other end of the feeding pipe (51) is coaxially located above the detection disc (2), a plurality of material guide pipes (52) are arranged on the peripheral wall of the feeding pipe (51), and the end of each material guide pipe (52) away from the feeding pipe (51) is opposite to the gap between two scraping strips (4).

7. The quality detection device for producing guaifenesin raw material medicine according to claim 6, characterized in that, A flow guide block (53) is arranged on the inner wall of the feeding pipe (51), the flow guide block (53) is in the shape of a sharp cone, and a plurality of concave surfaces (531) are arranged on the inclined surface of the flow guide block (53), and the plurality of concave surfaces (531) correspond to the plurality of material guide pipes (52) one by one.

8. The quality detection equipment for producing guaifenesin raw material medicine according to claim 7, wherein the inside of the feeding pipe (51) is further provided with an electric valve (54), the valve port of the electric valve (54) is provided in a funnel shape, and the valve port of the electric valve (54) is coaxially arranged with the flow guide block (53).

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