A device for culturing mouse tumor cells

Abstract

The application discloses a kind of mouse tumor cell culture devices, including device ontology, multiple placing racks are installed in device ontology, multiple placing racks top are all set with placing groove, the inside of multiple placing racks is all provided with access mechanism, access mechanism includes multiple placing plate, the inside of multiple placing plate is all separated into multiple placing chamber by multiple partition, the inside of multiple placing chamber is provided with correction mechanism, and drive mechanism is provided in device ontology.In the application, when multiple culture dishes need to be placed in the device ontology for cultivation, the access mechanism provided in the device ontology can be used to place the multiple culture dishes one by one, without manually placing and adjusting the spacing of the multiple culture dishes repeatedly, improving the efficiency of placing the multiple culture dishes in the device ontology, reducing the time of the culture dishes in the external environment, and improving the survival rate of mouse tumor cell cultivation.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of cell culture, in particular to a culture device for mouse tumor cells. BACKGROUND

[0002] Cell culture is a method that simulates the in-vivo environment to make cells survive, grow, reproduce and maintain the main structure and function. Cell culture is an indispensable process for the whole biological engineering technology and one of the biological cloning technologies. Cell culture itself is a large-scale cloning of cells. Culturing mouse tumor cells can provide important experimental models and tools for tumor research, and help to better understand the biological characteristics, growth mechanism and metastasis pathway of tumors, and provide scientific basis and technical support for the diagnosis, treatment and prevention of tumors. During the culturing process of mouse tumor cells, a culture device is needed to provide appropriate temperature and humidity for cell growth.

[0003] The culture device in the prior art needs to place multiple mouse tumor cells in multiple culture dishes respectively, and then manually place the multiple culture dishes in the culture device in order and adjust the distance between the multiple culture dishes to make the distance constant. This process is inefficient and can cause the culture dishes to be exposed to the external environment for a long time, which reduces the survival rate of the mouse tumor cells in the culture dishes during the subsequent culturing process and affects the normal culturing of the mouse tumor cells. SUMMARY

[0004] The present application aims to solve the problems in the prior art and provides a culture device for mouse tumor cells.

[0005] To achieve the above-mentioned purpose, the present application adopts the following technical solutions:

[0006] The culture device for mouse tumor cells comprises a device body, a sealing door is installed on the front of the device body, multiple placing racks are installed inside the device body, a placing slot for temporarily placing a culture dish is formed on the top of each placing rack, an access mechanism for automatically taking and placing culture dishes is arranged inside each placing rack, the access mechanism comprises multiple placing plates installed inside the placing rack, the inside of each placing plate is divided into multiple placing chambers by multiple partitions, a correction mechanism for correcting the position of the culture dish is arranged inside each placing chamber, and a driving mechanism for driving the correction mechanism to work is arranged on the upper and lower sides of the multiple placing racks inside the device body.

[0007] Optionally, the access mechanism further comprises two rectangular strips arranged above the plurality of placement plates, both groups of first electric telescopic rods are installed in the plurality of placement plates, and the telescopic ends of the two groups of first electric telescopic rods are connected with the rectangular strips close thereto.

[0008] Optionally, first sliding grooves are arranged on the sides of the two rectangular strips close to each other, first sliding blocks are installed in the two first sliding grooves, and the ends of the two first sliding blocks close to each other are connected with clamping plates for clamping and fixing the culture dishes through second electric telescopic rods.

[0009] Optionally, circular grooves are arranged on the inner bottoms of the plurality of placement cavities, and circular blocks are placed in the plurality of circular grooves.

[0010] Optionally, the correction mechanism comprises moving plates arranged on the four inner walls of the placement cavity, second sliding grooves are arranged on the inner bottom of the placement cavity, and second sliding blocks are installed at the bottoms of the four moving plates and can move back and forth in the second sliding grooves.

[0011] Optionally, a plurality of rectangular grooves are further arranged on the inner bottom of the placement cavity, rectangular blocks are installed at the bottoms of the four moving plates and can slide back and forth in the rectangular grooves, and springs are installed between the four rectangular blocks and the inner walls of the rectangular grooves on one side.

[0012] Optionally, connecting plates are rotatably installed at the bottoms of the four rectangular blocks and pass through the rectangular grooves, a connecting sleeve is arranged directly below the placement cavity, and the ends of the plurality of connecting plates away from the rectangular blocks are hingedly connected with the outer wall of the connecting sleeve.

[0013] Optionally, the driving mechanism comprises a plurality of third sliding grooves arranged on the inner walls of both sides of the device body, third sliding blocks are installed in the plurality of third sliding grooves, and the ends of the plurality of third sliding blocks away from the third sliding grooves are commonly connected with a mounting plate.

[0014] Optionally, a plurality of through grooves are arranged in the mounting plate, rotating blocks same in number as the placement cavities are rotatably installed in the plurality of through grooves, third electric telescopic rods are installed at the top ends of the plurality of rotating blocks, and the diameters of the third electric telescopic rods are smaller than the inner diameter of the connecting sleeve.

[0015] Optionally, rubber blocks are installed at the telescopic ends of the plurality of third electric telescopic rods, and two telescopic limiting rods are installed in the telescopic ends of the plurality of third electric telescopic rods.

[0016] The beneficial effects of the present application are:

[0017] 1. In this invention, when multiple culture dishes need to be placed inside the device body for culture, the multiple culture dishes can be placed sequentially by the access mechanism set inside the device body, eliminating the need for manual repeated placement and spacing adjustment of multiple culture dishes, improving the efficiency of placing multiple culture dishes inside the device body, reducing the time the culture dishes are in the external environment, and thus improving the survival rate of mouse tumor cell culture.

[0018] 2. In this invention, after the culture dish is placed inside the corresponding placement chamber, the distance between the culture dish and the inner wall of the placement chamber can be kept constant by the correction mechanism set inside the placement chamber, so as to ensure air circulation and uniform temperature inside the device body, which is conducive to the normal growth of tumor cells inside the culture dish.

[0019] 3. In this invention, after the culture dish is placed inside the placement chamber, its position is corrected by a correction mechanism. This also makes it easier to remove the culture dish later. When the third electric telescopic rod moves upward and pushes the circular block upward, the culture dish is located in the center of the top of the circular block. This makes the upward movement of the culture dish safer and more stable, and facilitates the two clamps to quickly and accurately clamp and fix the culture dish, thus improving the safety of the culture dish removal process.

[0020] 4. In this invention, after multiple culture dishes are placed sequentially inside multiple placement chambers, multiple rotating blocks inside the mounting plate above the placement rack can be controlled to drive multiple third electric telescopic rods to rotate downwards to a vertical state. Then, the mounting plate and the vertically positioned third electric telescopic rods below it are controlled to move downwards together, and the telescopic ends of multiple third electric telescopic rods are controlled to extend downwards, causing multiple rubber blocks to contact the lids on the top of the culture dishes. The downward-moving rubber blocks press down on the lids of the culture dishes, ensuring that multiple culture dishes are sealed in the placement chambers. This avoids a situation where the seal between the culture dish lids and the culture dishes is not tight, resulting in a low survival rate of mouse tumor cells inside the culture dishes. Attached Figure Description

[0021] To facilitate understanding by those skilled in the art, the present invention will be further described below with reference to the accompanying drawings.

[0022] Figure 1 This is a schematic diagram of the overall structure of a mouse tumor cell culture device proposed in this invention;

[0023] Figure 2 This is a schematic diagram of the internal structure of the device body in this invention;

[0024] Figure 3 This is a schematic diagram of the structure of the placement rack and mounting plate in this invention;

[0025] Figure 4 Structure diagram of the bottom of the placing rack in the application;

[0026] Figure 5 Structure diagram of the mounting plate in the application;

[0027] Figure 6 Structure diagram of the third electric telescopic rod in the application;

[0028] Figure 7 Structure diagram of the placing plate and the rectangular strip plate in the application;

[0029] Figure 8 Structure diagram of the rectangular strip plate separated from the placing plate in the application;

[0030] Figure 9 Structure diagram of the plurality of moving plates separated from the placing plate in the application;

[0031] Figure 10 Structure diagram of the correction mechanism in the application.

[0032] In the figure: 1, device body; 2, sealing door; 3, placing rack; 4, mounting plate; 5, third sliding groove; 6, third sliding block; 7, through slot; 8, third electric telescopic rod; 9, placing groove; 10, rectangular strip plate; 11, placing plate; 12, connecting sleeve; 13, rotating block; 14, telescopic limiting rod; 15, rubber block; 16, clamping plate; 17, round block; 18, moving plate; 19, first sliding groove; 20, first electric telescopic rod; 21, first sliding block; 22, second electric telescopic rod; 23, partition plate; 24, round slot; 25, rectangular slot; 26, second sliding groove; 27, connecting plate; 28, spring; 29, second sliding block; 30, rectangular block. DETAILED DESCRIPTION

[0033] The technical solutions of the application will be described clearly and completely below in conjunction with the embodiments. Obviously, the described embodiments are only a part of the embodiments of the application, rather than all the embodiments. Based on the embodiments in the application, all the other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the application.

[0034] REFERENCE Figures 1-10The utility model provides a mouse tumor cell culture device, including device body 1, the front surface of device body 1 is equipped with sealing door 2, the inside of device body 1 is equipped with multiple placing rack 3, the top of multiple placing rack 3 is all equipped with the placing groove 9 for temporarily placing culture dish, the inside of multiple placing rack 3 is all provided with the access mechanism for automatically taking and placing culture dish, and the access mechanism includes multiple placing plate 11 installed in the inside of placing rack 3, the inside of multiple placing plate 11 is separated into multiple placing chamber by multiple partition 23 of setting, the inside of multiple placing chamber is provided with the correction mechanism for correcting the position of culture dish, and the inside of device body 1 is provided with the drive mechanism for driving the correction mechanism to work on the upper and lower sides of multiple placing rack 3.

[0035] As a kind of technical optimization scheme of the utility model, access mechanism further includes two rectangular slats 10 arranged above multiple placing plate 11, two groups of first electric telescopic rod 20 are installed in the inside of multiple placing plate 11, and the telescopic end of two groups of first electric telescopic rod 20 is respectively connected with the rectangular slat 10 close to it.The telescopic end of first electric telescopic rod 20 telescopes, can drive rectangular slat 10 to move up and down on the top of placing plate 11, i.e. the height of rectangular slat 10 can be adjusted.

[0036] As a kind of technical optimization scheme of the utility model, the outer wall of the side close to two rectangular slats 10 is equipped with first sliding slot 19, first sliding block 21 is installed in the inside of two first sliding slots 19, and the end close to two first sliding blocks 21 is connected with clamping plate 16 for clamping and fixing culture dish by second electric telescopic rod 22.In the inside of two first sliding slots 19, first linear motor is pre-installed, first linear motor can drive first sliding block 21 to move back and forth in the inside of first sliding slot 19, so as to drive second electric telescopic rod 22 and clamping plate 16 to move in turn.

[0037] As a kind of technical optimization scheme of the utility model, the inner bottom surface of multiple placing chamber is equipped with circular groove 24, and circular block 17 is placed in the inside of multiple circular grooves 24.

[0038] As a kind of technical optimization scheme of the utility model, correction mechanism includes moving plate 18 arranged on the four inner walls of placing chamber, second sliding slot 26 is formed on the inner bottom surface of placing chamber, and second sliding block 29, movable in second sliding slot 26, is installed on the bottom of four moving plates 18.The second sliding block 29 arranged on the bottom of moving plate 18 can limit the moving track of moving plate 18, so that it keeps linear state movement.

[0039] As a technical optimization of the present invention, the inner bottom surface of the placement chamber is provided with a plurality of rectangular grooves 25, and the bottom of the four movable plates 18 is provided with rectangular blocks 30 that can slide back and forth in the rectangular grooves 25. Springs 28 are installed between the four rectangular blocks 30 and one side inner wall of the rectangular grooves 25.

[0040] As a technical optimization of the present invention, the bottom ends of the four rectangular blocks 30 are rotatably mounted with connecting plates 27 through the rectangular grooves 25. A connecting sleeve 12 is provided directly below the placement chamber. The ends of the multiple connecting plates 27 away from the rectangular blocks 30 are hinged to the outer wall of the connecting sleeve 12. By pulling down the connecting sleeve 12, the four connecting plates 27 can be rotated in the same direction, thereby causing the four rectangular blocks 30 to move in the same direction inside the rectangular grooves 25. This, in turn, causes the four moving plates 18 to move in the same direction, correcting the position of the culture dish placed inside the placement chamber. This ensures that the distance between the culture dish and the inner wall of the placement chamber is constant, guaranteeing air circulation and uniform temperature inside the device body 1, which is conducive to the normal growth of mouse tumor cells.

[0041] As a technical optimization of the present invention, the driving mechanism includes multiple third slide grooves 5 formed on the inner walls of both sides of the device body 1. Each of the multiple third slide grooves 5 has a third slider 6 installed inside it. The ends of the multiple third sliders 6 furthest from the third slide grooves 5 are connected to a mounting plate 4. Each of the multiple third slide grooves 5 has a second linear motor pre-installed inside it. The multiple second linear motors can respectively drive the multiple third sliders 6 to move up and down inside the third slide grooves 5, thereby driving the mounting plate 4 to move up and down inside the device body 1.

[0042] As a technical optimization of the present invention, the mounting plate 4 has multiple through slots 7 inside, and each of the multiple through slots 7 has a rotating block 13 rotatably mounted therein, the same number as the placement chamber. A third electric telescopic rod 8 is mounted on the top of each of the multiple rotating blocks 13, and the diameter of the third electric telescopic rod 8 is smaller than the inner diameter of the connecting sleeve 12. A driving device is pre-installed inside the mounting plate 4, and the output end of the driving device is connected to the rotating part of the rotating block 13 and the through slot 7, thereby enabling the rotating block 13 to rotate inside the through slot 7.

[0043] As a technical optimization scheme of the application, the telescopic ends of the plurality of third electric telescopic rods 8 are each provided with a rubber block 15, and the telescopic ends of the plurality of third electric telescopic rods 8 are each provided with two telescopic limiting rods 14. The mounting plate 4 moves upward in the inside of the device body 1, so as to drive the plurality of third electric telescopic rods 8 to pass through the connecting sleeve 12 in sequence, and then the telescopic ends of the two telescopic limiting rods 14 are controlled to extend, and with the downward movement of the mounting plate 4, the telescopic ends of the two telescopic limiting rods 14 can hinder the downward movement of the third electric telescopic rod 8 in the connecting sleeve 12, so as to drive the connecting sleeve 12 to move downward in sequence, and realize the effect of driving the plurality of moving plates 18 to move in the direction of approaching each other.

[0044] In the application, when a user uses the device, the culture dish with mouse tumor cells placed inside needs to be placed in the device body 1 for culture. After the sealing door 2 arranged on the front of the device body 1 is opened, the culture dish is placed in the inside of the corresponding placing groove 9 on the top of the placing rack 3, the telescopic ends of the two corresponding second electric telescopic rods 22 are controlled to extend, the two clamping plates 16 are driven to move in the direction of approaching each other, the culture dish in the inside of the placing groove 9 is clamped and fixed, then the two corresponding first sliding blocks 21 are controlled to move in the inside of the first sliding groove 19, the clamped and fixed culture dish is driven to move to the position right above the corresponding placing chamber, the plurality of third sliding blocks 6 are controlled to move upward in the inside of the third sliding groove 5, the mounting plate 4 and the corresponding third electric telescopic rod 8 on the top of the mounting plate 4 are driven to move upward, so that the corresponding third electric telescopic rod 8 passes through the connecting sleeve 12 below the placing chamber and abuts against the bottom end of the circular block 17, the telescopic end of the third electric telescopic rod 8 is controlled to extend, so that the telescopic rubber block 15 pushes the circular block 17 to move upward in the placing chamber and abut against the bottom end of the culture dish, finally the telescopic ends of the two second electric telescopic rods 22 drive the clamping plates 16 to retract and reset, so that the culture dish is placed on the top of the circular block 17, and with the telescopic end of the third electric telescopic rod 8 retracted and reset downward, the circular block 17 is reset in sequence, so that the culture dish is stably placed in the inside of the placing chamber, and the effect of automatically placing the culture dish in the inside of the device body 1 is achieved. When a plurality of culture dishes need to be placed in the device body 1 for culture, the above steps can be repeated to place the plurality of culture dishes in sequence, without manually placing the plurality of culture dishes repeatedly, so as to improve the efficiency of placing the culture dishes in the device body 1 and reduce the time of the culture dishes in the external environment.

[0045] And when the culture dish inside the device body 1 needs to be taken out, the above steps can be repeated. By extending the telescopic end of the third electric telescopic rod 8, the circular block 17 and the culture dish are pushed to move upward together to a specified height inside the placement chamber. Then, by means of the two first sliders 21, the clamping plates 16 are moved to the two sides of the culture dish. After the two clamping plates 16 clamp and fix the culture dish, the two first sliders 21 are used to move the clamping plates 16 to the inside of the placement slot 9 for placement. The staff can quickly take out the culture dish by opening the sealing door 2, reducing the contact time between the device body 1 and the external environment, thereby benefiting the culture of mouse tumor cells in the device body 1 and improving the survival rate of mouse tumor cells.

[0046] At the same time, after the above access mechanism places the culture dish inside the corresponding placement chamber, the telescopic end of the third electric telescopic rod 8 can be controlled to retract. However, the third electric telescopic rod 8 is still inside the connecting sleeve 12. The telescopic ends of the two telescopic limit rods 14 of the third electric telescopic rod 8 can be controlled to extend. During the downward movement and resetting of the mounting plate 4, the telescopic ends of the two telescopic limit rods 14 abut against the top end of the connecting sleeve 12, so that the third electric telescopic rod 8 cannot smoothly move downward inside the connecting sleeve 12, but can only move downward together with the connecting sleeve 12. With the downward movement of the connecting sleeve 12, the four connecting plates 27 are naturally rotated toward the approaching direction, thereby driving the four rectangular blocks 30 to move toward the approaching direction inside the rectangular slot 25, driving the four moving plates 18 to move together toward the approaching direction inside the placement chamber, correcting the position of the culture dish placed inside the placement chamber, and after correcting the position of the culture dish, the telescopic ends of the two telescopic limit rods 14 are controlled to retract, so that the connecting sleeve 12 is no longer subjected to the downward pulling force of the third electric telescopic rod 8. By means of the elastic resetting of the multiple springs 28, the multiple moving plates 18 are moved and reset inside the placement chamber, avoiding the influence of the multiple moving plates 18 on the placement of the culture dish, keeping the distance between the culture dish and the inner wall of the placement chamber constant, ensuring the air circulation and uniform temperature inside the device body 1, and facilitating the normal growth of tumor cells inside the culture dish.

[0047] After placing the culture dish inside the placement chamber, the correction mechanism can also correct the position of the culture dish, which facilitates the upward movement of the third electric telescopic rod 8 pushing the circular block 17 upward during the subsequent process of taking out the culture dish. The culture dish is located at the central position on the top of the circular block 17, making the upward movement of the culture dish safer and more stable, facilitating the subsequent quick and accurate clamping and fixing of the culture dish by the two clamping plates 16, and improving the safety during the process of taking out the culture dish.

[0048] After the multiple culture dishes are placed in the multiple placement chambers in sequence, the multiple rotating blocks 13 in the mounting plate 4 above the placement rack 3 are controlled to rotate 180 degrees downward in the through slot 7, driving the multiple third electric telescopic rods 8 to rotate downward to a vertical state, then the multiple third sliding blocks 6 are controlled to move downward in the third sliding slot 5, driving the mounting plate 4 and the third electric telescopic rods 8 below it to move downward to a vertical state, until the mounting plate 4 moves to a position close to the placement rack 3, then the multiple third electric telescopic rods 8 are controlled to extend downward, driving the multiple rubber blocks 15 to contact the lids on the top of the culture dishes, and pressing the lids of the culture dishes by means of the downward moving rubber blocks 15, ensuring that the multiple culture dishes are in a sealed state in the placement chamber, avoiding the situation that the sealing between the culture dish lid and the culture dish is not tight, resulting in a low survival rate of mouse tumor cells in the culture dish.

[0049] Moreover, when the multiple culture dishes are placed in the device body 1 for mouse tumor cell culture, the culture dishes are placed statically in the device body 1, and long-term static placement can cause the culture solution in the culture dish to precipitate or solidify, affecting the normal culture of mouse tumor cells. When it is found that the culture solution in the culture dish has precipitated, the mounting plate 4 below the multiple placement racks 3 is controlled to move upward, driving the multiple third electric telescopic rods 8 to move upward and pass through the corresponding connecting sleeve 12, the third electric telescopic rod 8 below the culture dish where the precipitation phenomenon occurs is controlled to extend and retract upward, pushing the round block 17 and the culture dish on the top of it to move up and down in the placement chamber, shaking the culture solution in the culture dish, avoiding the culture solution from precipitating or solidifying due to long-term static placement, reducing the influence on the culture of mouse tumor cells.

[0050] If the mouse tumor cells inside the partial culture dish are found to have abnormal growth, such as a large number of cell deaths or the growth of other bacteria inside the culture dish, the above steps of taking the culture dish out of the placement chamber can be repeated, and the culture dish can be placed inside the placement groove 9. After the sealing door 2 is opened by the worker, the culture dish with abnormal conditions can be observed in the first time, and it can be quickly taken out from the inside of the device body 1 in time, improving the efficiency of handling the culture dish with abnormal conditions. If there are a large number of culture dishes with abnormal conditions, after the first culture dish is placed inside the placement groove 9, the two clamping plates 16 can take out the subsequent culture dishes from the placement chamber, and the two groups of corresponding first electric telescopic rods 20 can be controlled to extend upward, driving the two rectangular plates 10 and the clamping plates 16 to move upward together, so that the height of the culture dish clamped and fixed by the two clamping plates 16 increases. During the movement of the two first sliders 21 in the first sliding groove 19, the subsequent culture dish can be moved above the first culture dish, and the two groups of first electric telescopic rods 20 can be controlled to retract downward, driving the subsequent culture dish to be stacked above the first culture dish. The subsequent other culture dishes with abnormal conditions can be stacked one by one.

[0051] After stacking the multiple culture dishes with abnormal conditions on the top of the placement rack 3, in order to avoid the multiple stacked culture dishes from tilting and falling down during the opening of the sealing door 2 by the worker, the mounting plate 4 above the placement rack 3 can be controlled to move downward until the bottom end of the mounting plate 4 abuts against the top of the uppermost culture dish, so that the mounting plate 4 above can press and fix the multiple stacked culture dishes, avoiding the problem of damage to the stacked culture dishes, and improving the safety of the worker during the taking of the culture dishes with abnormal conditions.

[0052] The preferred embodiments disclosed above are only used to help explain the application. The preferred embodiments do not describe all the details, nor limit the application to the specific embodiments described. Obviously, many modifications and changes can be made according to the content of the present application. The embodiments are selected and described in detail in order to better explain the principles and practical applications of the application, so that those skilled in the art can well understand and utilize the application. The application is limited by the claims and their entire scope and equivalents.

Claims

1. A device for culturing mouse tumor cells, comprising a device body (1), characterized in that, The front of the device body (1) is equipped with a sealing door (2). Multiple placement racks (3) are installed inside the device body (1). The top of each of the multiple placement racks (3) is provided with a placement slot (9) for temporarily placing the culture dish. Each of the multiple placement racks (3) is provided with a storage and retrieval mechanism for automatically picking up and placing the culture dish. The storage and retrieval mechanism includes multiple placement plates (11) installed inside the placement rack (3). Each of the multiple placement plates (11) is divided into multiple placement chambers by multiple partitions (23). Each of the multiple placement chambers is provided with a correction mechanism for correcting the position of the culture dish. The device body (1) is provided with a drive mechanism for driving the correction mechanism on both the upper and lower sides of the multiple placement racks (3). The storage and retrieval mechanism also includes two rectangular strips (10) disposed above multiple placement plates (11). The outer walls of the two rectangular strips (10) that are close to each other are provided with first sliding grooves (19). The interiors of the two first sliding grooves (19) are each equipped with first sliders (21). The ends of the two first sliders (21) that are close to each other are connected to clamps (16) for clamping and fixing the petri dishes through a second electric telescopic rod (22). The inner bottom surface of each of the multiple placement chambers is provided with a circular groove (24), and a circular block (17) is placed inside each of the multiple circular grooves (24). The correction mechanism includes movable plates (18) set on the four inner walls of the placement chamber. The inner bottom surface of the placement chamber is also provided with multiple rectangular grooves (25). The bottom of each of the four movable plates (18) is equipped with a rectangular block (30) that can slide back and forth in the rectangular groove (25). A spring (28) is installed between each of the four rectangular blocks (30) and one inner wall of the rectangular groove (25). The bottom of each of the four rectangular blocks (30) passes through the rectangular groove (25) and is rotatably mounted with a connecting plate (27). A connecting sleeve (12) is set directly below the placement chamber. The ends of the multiple connecting plates (27) away from the rectangular blocks (30) are hinged to the outer wall of the connecting sleeve (12). The driving mechanism includes multiple third slide grooves (5) opened on both sides of the inner wall of the device body (1). Each of the multiple third slide grooves (5) is equipped with a third slider (6). The end of the multiple third sliders (6) away from the third slide groove (5) is connected to a mounting plate (4). The drive mechanism also includes a third electric telescopic rod (8), the diameter of which is smaller than the inner diameter of the connecting sleeve (12). Rubber blocks (15) are installed on the telescopic ends of the multiple third electric telescopic rods (8), and two telescopic limit rods (14) are installed inside the telescopic ends of the multiple third electric telescopic rods (8).

2. The mouse tumor cell culture device according to claim 1, characterized in that, Each of the multiple placement plates (11) is equipped with two sets of first electric telescopic rods (20), and the telescopic ends of the two sets of first electric telescopic rods (20) are respectively connected to the rectangular strips (10) that are close to them.

3. The mouse tumor cell culture device according to claim 1, characterized in that, The inner bottom surface of the placement chamber is provided with multiple second sliding grooves (26), and the bottom of each of the four movable plates (18) is equipped with a second slider (29) that can move back and forth in the second sliding groove (26).

4. The mouse tumor cell culture device according to claim 1, characterized in that, The mounting plate (4) has multiple through slots (7) inside, and each through slot (7) has a rotating block (13) with the same number of placement chambers inside. Multiple third electric telescopic rods (8) are respectively installed on the top of the corresponding rotating block (13).

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