Transdermal absorption hydrogen injection antioxidant mask and preparation method thereof

Abstract

The invention relates to the field of masks, in particular to a transdermal absorption hydrogen injection antioxidant mask and a preparation method thereof. According to the present invention, by using the hydrogen production, hydrogen storage and transdermal functions provided by the silicon powder, the permeation trend of the hydrogen produced by the traditional hydrogen production mask to the skin is improved, and the better oxidation resistance is provided.

Description

Technical Field

[0001] The present application relates to the field of facial masks, and in particular to an antioxidant facial mask for transdermal hydrogen injection and a preparation method thereof. Background Art

[0002] Hydrogen-producing transdermal facial masks usually consist of hydrogen-producing materials (such as hydrogen powder, solid hydrogen storage particles) and facial mask matrices (such as non-woven fabrics, gels or dry films), and are also called hydrogen water masks. Hydrogen molecules are easily able to enter mitochondria and cell nuclei to scavenge free radicals. Research shows that hydrogen exerts antioxidant activity by specifically eliminating hydroxyl free radicals, which helps to improve skin elasticity, provide anti-aging and whitening effects.

[0003] Under normal circumstances, the mechanism of hydrogen production by facial mask materials, such as magnesium-based alloys or corresponding metal oxides and hydroxides as hydrogen-producing materials, uses metals to produce hydrogen in a water-containing facial mask system and permeates through the skin surface to exert effects. There are already many uses of the above products. However, in the above solutions, the problem of hydrogen escape after the facial mask produces hydrogen generally cannot be solved, resulting in poor absorption performance in the skin direction. Summary of the Invention

[0004] The purpose of the present application is to provide a facial mask structure that can produce hydrogen while increasing the degree of hydrogen penetration through the skin and reducing the escape of hydrogen to the outside, thereby improving its antioxidant ability for the skin.

[0005] First of all, the present application provides an antioxidant facial mask for transdermal hydrogen injection, which includes an inner layer, a filling layer and an outer layer from the inside out; The inner layer, the filling layer and the outer layer are all made of non-woven fabric material. The porosity of the outer layer is 0.7 to 0.9 times that of the inner layer, and / or the fiber diameter of the outer layer is 0.7 to 0.9 times that of the inner layer; The filling layer includes a first base layer formed by first fibers and a hydrogen-producing material loaded in the first base layer. The hydrogen-producing material includes silicon powder and metal powder, and the metal powder is magnesium powder, zinc powder or a combination of magnesium powder and zinc powder; in the filling layer, the loading mass percentage of silicon powder is 5 to 10%, and the loading percentage of the metal powder is 2.5 to 5%; The inner layer at least includes a second base layer and phospholipids loaded in the second base layer.

[0006] In the above-mentioned facial mask system, a three-layer overall structure is adopted. The outer layer has a lower porosity, and the inner layer has a higher porosity, forming a pore structure with a certain gradient as a whole. This enables the pressure difference of gas escaping inward and outward during the dissipation process, reducing the dissipation of hydrogen. On this basis, a basic structure for hydrogen generation is formed in the filling layer. This basic structure contains metal powder and silicon powder. Among them, the silicon powder can form a certain hydrogen adsorption and slow-release system, and at the same time, it forms micro-reaction cavities on the surface of the silicon powder by using the microporous structure, thereby regulating the hydrogen generation rate in the system.

[0007] On this basis, after controlling the release of hydrogen by using the already formed hydrogen production and storage space, phospholipids are used in the inner layer to improve the wettability of the fiber to the skin surface. On the one hand, phospholipids can moisten the skin surface, and on the other hand, they also reduce the irritation of the skin by the system of metal powder and silicon powder. At the same time, the inner layer is used to block the filling layer and the skin, improving the skin's absorption performance of hydrogen while making the facial mask have better mildness and reducing irritation to the skin.

[0008] Preferably, in the filling layer, the metal powder is a mixture of zinc powder and magnesium powder, and the mass ratio of zinc powder to magnesium powder is 1∶6 - 15. It also contains magnesium hydroxide, and the mass of magnesium hydroxide is 2 - 5 times the mass of the metal powder, and the loading mass percentage is not higher than 20%. Using magnesium hydroxide can, on the one hand, adjust the overall pH value, making the reaction process in the filling layer more stable, and at the same time, it also forms a filler structure to adsorb the precipitation of metal hydroxides and metal carbonates generated during hydrogen production, thereby improving the overall skin feel of the facial mask.

[0009] Preferably, the filling layer further contains sodium bicarbonate, and the loading mass percentage of sodium bicarbonate is 15 - 25%. In this solution, sodium bicarbonate has buffering properties, can overall control the pH stability, further reduce the irritation to the skin, and at the same time increase the hydrogen production.

[0010] Preferably, it further includes sodium alginate, and the loading mass percentage of sodium alginate is 1 - 3%.

[0011] Sodium alginate can, on the one hand, be used as a viscous material to improve the connection tightness between the inner layer and the filling layer, and on the other hand, it also has better wettability and adsorption properties, making the structure of the facial mask stronger as a whole and causing less irritation to the skin.

[0012] It should be noted that in the above text, the calculation method of the loading mass is the ratio of the mass of the substance involved to the mass of the first base layer.

[0013] Preferably, the first fiber is a combination of modal fiber and viscose fiber, and the mass ratio of modal fiber to viscose fiber is 1∶0.2 - 0.3.

[0014] In the above solution, the combination of modal fiber and viscose fiber is used as the filling layer. First of all, the modal fiber as a whole provides softer performance and better hydrophilicity. Its property of being wettable by water helps to increase the rate of hydrogen production, thereby providing better hydrogen production performance. At the same time, the better softness of the modal fiber can fit the skin and reduce its irritation to the skin. On this basis, a certain amount of viscose fiber is added. On the one hand, it provides better bonding performance, enabling a tighter system to be formed between the inner surface layer, the outer surface layer and the filling layer. On the other hand, it also helps the adsorption of hydrogen-producing materials and improves hydrogen production performance.

[0015] Preferably, the ratio of the particle size of the silicon powder to the diameter of the first fiber is 0.1 - 0.8:1.

[0016] In the above solution, silicon powder with a smaller particle size is selected. On the one hand, its catalytic reaction and hydrogen storage effects are better, which can increase the hydrogen production and reduce the escape of hydrogen, while controlling the reaction rate of hydrogen. On the other hand, the silicon powder with a smaller particle size is overall more delicate. Even if some of it adheres to the skin surface, it is not easy to cause irritation, and it also helps hydrogen to penetrate the skin better.

[0017] Preferably, the outer surface layer is a combination of cotton fiber and PET fiber, and the mass ratio of the cotton fiber to the PET fiber is 1:0.2 - 0.5.

[0018] The cotton fiber provides softness, while the PET fiber provides the strength and barrier properties of the outer surface layer. In the above solution, while making the mask have a softer structure, it also further reduces the possibility of hydrogen escaping outward.

[0019] In addition, it also includes a wetting agent for wetting the inner surface layer, the filling layer and the outer surface layer before use. The wetting agent is a water-glycerol mixed system. In the water and glycerol mixed system, it can improve the wetting degree and affinity of the mask for the skin surface, and at the same time, it also helps to control the hydrogen production rate and reduce the escape of hydrogen.

[0020] On the other hand, the present application also relates to a preparation method of the above transdermal absorption hydrogen injection antioxidant mask, including the following steps: S1. Preparation of materials: Configure the inner surface layer, the first base layer and the second base layer, and weigh the required loaded system; S2. Crushing: Crush the materials in the filling layer except the first base layer, and screen out large particles; S3. Mixing: Mix the raw materials crushed in S2 with water at a mass concentration of 5 - 30% to obtain a first mixture; dissolve phospholipids in water to prepare a second mixture; wherein, in the second mixture, the mass ratio of phospholipids to the second base layer is 0.02 - 0.5:1; S4. Coating: Coating the first mixture on the first base layer and coating the second mixture on the second base layer; S5. Hot pressing: Stacking the inner surface layer, the filling layer and the outer surface layer, and making the side of the inner surface layer coated with the second mixture fit with the side of the filling layer coated with the first mixture. Subsequently, hot pressing is carried out under wet conditions, the hot pressing temperature is 300 - 400 °C, the pressure is 2 - 4 t, and the contact time is 1 - 5 s.

[0021] S6. Disinfection and packaging.

[0022] In the above solution, the treatment steps of coating - hot pressing are adopted. First, the hydrogen - producing material is mainly distributed on the side of the first base layer facing the inner surface layer by using the coating performance. Subsequently, the three layers are combined by hot pressing to form a relatively dense and firm structure. Overall, the hot pressing step can reduce the surface roughness, improve its affinity for the skin, and at the same time make the three - layer fibers bond better together by hot pressing. Overall, it has better hydrogen - producing and reducing - dissipation performance and better skin fit.

[0023] In summary, the present application provides a transdermal absorption hydrogen - injecting antioxidant facial mask and its preparation method. It utilizes the hydrogen - producing, hydrogen - storing, and transdermal functions provided by silicon powder, thereby improving the tendency of hydrogen generated by traditional hydrogen - producing facial masks to penetrate into the skin and providing better antioxidant performance. Specific embodiments

[0024] The solution in the present application is further elaborated through the following specific embodiments.

[0025] In the present application, the hydrogen transdermal performance of the system is measured through the following experiments.

[0026] Prepare a piece of fresh pigskin with a thickness controlled at 0.5 mm (error not exceeding 10%). Fix the pigskin on the diffusion cell with the stratum corneum facing up and the dermis facing down and contact it with physiological saline containing methylene blue - platinum hydrogen chromogenic reagent, where the added concentration of the chromogenic reagent is 5% (volume concentration). Cover the prepared facial mask on the side of the pigskin stratum corneum, and the transdermal performance of the facial mask can be determined by the fading time in the physiological saline.

[0027] In addition, the softness is measured for its flexural rigidity with reference to ISO 9073 - 7.

[0028] In the following embodiments, multiple groups of experiments are designed to verify the hydrogen - producing transdermal performance of the transdermal absorption hydrogen - injecting facial mask and the softness of the facial mask itself under different preparation methods. At the same time, some experimental groups are experienced by subjects to measure their skin feelings. Specifically, the skin feelings are judged by 10 volunteers through scoring, where 1 point is the worst and 10 points is the best.

[0029] Example 1. The main purpose in this example is to study the component content loaded in the filler to determine the hydrogen transdermal performance. Specifically, the inner surface layer, the filling layer, and the outer surface layer are controlled in this example.

[0030] In this example, the specific preparation method is as follows: S1. Preparation of materials: Configure the layer structures in the inner surface layer, the filling layer, and the outer surface layer, and weigh the required loaded system; among them, the outer surface layer is a spunlace non-woven fabric obtained by configuring cotton fiber and PET fiber in a mass ratio of 1:0.3, the filling layer is a spunlace non-woven fabric obtained by mixing modal fiber and viscose fiber in a mass ratio of 1:0.25, and the inner surface layer first configures a modal fiber spunlace non-woven fabric as the second base layer. Among them, as is well known, by adjusting the fiber diameter and spunlace conditions of the non-woven fabric, the porosity of the product can be adjusted. Since the non-woven fabrics used in this application are directly purchased from manufacturers, the preparation process of the non-woven fabric will not be elaborated here.

[0031] S2. Crushing: Crush the materials in the filling layer except the first base layer to 140 mesh, and screen out large particles; S3. Mixing: Mix the raw materials crushed in S2 with water at a mass concentration of 20% to obtain the first mixture; dissolve phospholipids in water to prepare the second mixture; S4. Coating: Coat the first mixture on the first base layer, and coat the second mixture on the second base layer, where the mass of phospholipids used is 0.03 times the mass of the second base layer; S5. Hot pressing: Stack the inner surface layer, the filling layer, and the outer surface layer, and make the side of the inner surface layer coated with the second mixture fit with the side of the filling layer coated with the first mixture, and then perform hot pressing under wet conditions. The hot pressing temperature is 300 °C, the pressure is 4t, and the contact time is 3s.

[0032] S6. Disinfection and packaging.

[0033] In the final product, the thickness of the filling layer is 0.82 mm, the thickness of the inner surface layer filling layer is 0.28 mm, and the thickness of the outer surface layer is 0.24 mm. Specifically, in the outer surface layer, the fiber diameters of cotton fiber and PET fiber are 19 μm, the porosity is 58%, the porosity of modal fiber in the inner surface layer is 70%, and the fiber diameter is 25 μm. The above parameters are measured after hot pressing. The filling layer is a mixed system of modal fiber non-woven fabric and viscose fiber, the fiber diameter is 20 μm, and the porosity is 84%. Overall, a scheme where the thickness of the filling layer is 50-75% of the total thickness and the total thickness of the filling layer does not exceed 1 mm is better, which can maintain a good hydrogen generation effect and at the same time take into account a relatively soft skin feel. In fact, adjustments can also be made during the actual preparation process.

[0034] In this embodiment, in order to keep the basic hydrogen production performance unchanged, the mass of the metal powder in the filling layer is controlled to remain unchanged, and the added masses of other components are shown in Table 1 specifically.

[0035] Table 1 In the above table, the particle sizes of the selected zinc powder and magnesium powder do not exceed 100 μm, and the average particle size of the silicon powder is 10 μm.

[0036] The above embodiment is experimentally detected, and the results are shown in Table 2.

[0037] Table 2 Through the above experiments, it can be clearly seen that in this reaction system, the silicon powder generally helps the process of hydrogen production through the skin to occur, and at the same time, it will also significantly improve the overall bending stiffness. Therefore, it is necessary to control the mass of the silicon powder to be 5-10% of the overall mass of the filling layer. Otherwise, excessive hardness will cause the overall mask to be too hard and affect the skin feel. Secondly, in the system, it can be seen that the magnesium hydroxide system has an obvious effect on the hydrogen production performance, and because the magnesium hydroxide has a more rounded shape, its influence on the skin feel is less, and it can be added in a larger amount. At the same time, sodium bicarbonate can play a buffering effect in the system, and it has an obvious improvement effect on the stability of the hydrogen production performance. The addition amount for the best skin feel is preferably 15-20% of the mass of the non-woven fabric in the filling layer. Sodium alginate can also improve the skin feel and hydrogen permeation performance in the system, but when its addition amount is too much, it will instead cause it to overflow to the inner surface layer and cause the skin feel of the inner surface layer to deteriorate.

[0038] Example 2, in this example, on the basis of Examples 1-4, silicon powders with different particle sizes are used, and the optimal usage amount ranges of each silicon powder are measured. The specific results are shown in Table 3.

[0039] Table 3 From the above experimental data, it can be seen that there are relatively obvious requirements for the particle size of the silicon powder. The increase in the particle size of the silicon powder will not only affect the bending stiffness, but also significantly affect the skin feel of the mask. In addition, as shown in Examples 2-4 to 2-6, too small particle size will cause the silicon powder to have a relatively obvious adsorption of hydrogen, and then cause the hydrogen permeation performance to deteriorate significantly.

[0040] Example 3, in this example, on the basis of Examples 1-4, the fiber ratio of the filling layer is adjusted, and the experimental results are shown in Table 4.

[0041] Table 4 In the above solution, the fiber diameter of the filling layer remains unchanged, and only the choice of fibers is replaced, which has no obvious effect on its porosity as a whole.

[0042] It can be seen from the above experiments that in this application, a mixed system of modal fiber and viscose fiber is used, which can not only maintain a low stiffness level and improve skin feel and softness. Although the addition of modal fiber significantly improves the softness, excessive modal fiber will also lead to weak bonding performance between the three layers. On the one hand, hydrogen is likely to escape, and on the other hand, it also has a certain impact on the overall skin feel.

[0043] Example 4. In this example, on the basis of Examples 1-4, the addition amount of phospholipids in the inner surface layer is adjusted, and the specific experimental results are shown in Table 5.

[0044] Table 5 From the above experimental results, it can be seen that phospholipids can significantly improve the hydrogen permeation performance and skin feel. Phospholipids themselves have a certain skin-moisturizing effect, and at the same time they have good compatibility with the skin, which is more conducive to the skin's absorption of other substances, especially hydrogen. The mass of phospholipids is preferably 0.01-0.05 times that of the second base layer. After exceeding 0.05 times, although there is no obvious change in its overall performance, on the one hand, the price of phospholipids is relatively high, and on the other hand, phospholipids themselves are prone to transfer to the filling layer after long-term storage, which may lead to a decrease in hydrogen production performance after long-term storage.

[0045] Example 5. In this example, on the basis of Examples 1-4, the selection of the outer surface layer fibers, porosity and the fiber diameter used are adjusted, and the adjustment results are shown in Table 6.

[0046] Table 6 In the above solution, the porosity can be jointly adjusted by the fiber diameter, hydroentangling conditions and hot pressing. In order to adjust the porosity, the prepared outer surface layer can be hot-pressed alone to reduce the porosity. Since the hot-pressing step can make the whole more flat and the skin feel better, hot pressing will not affect other properties, and the hot-pressing conditions will not be elaborated here.

[0047] The above examples are experimented, and the results are shown in Table 7.

[0048] Table 7 In the above solution, a denser outer layer can be seen, such as having a lower porosity or a smaller fiber diameter, which helps to reduce the escape of hydrogen, promotes the diffusion of hydrogen towards the skin side, and thus reduces the time for the reagent to change color. However, it will also lead to a worse skin feel and a worse bending stiffness. At the same time, in the selection of fibers, an increase in the usage amount of PET fibers will increase the stiffness, reduce the time for the reagent to change color, and reduce the escape of hydrogen. The overall mass ratio of cotton fibers to PET fibers is preferably in the range of 1:0.2 to 0.5.

[0049] This specific embodiment is only an explanation of the present application and does not limit the present application. After reading this specification, those skilled in the art can make modifications to this embodiment without creative contributions as needed, but as long as they are within the scope of the claims of the present application, they are protected by the patent law.

Claims

1. A transdermal absorption hydrogen-injected antioxidant facial mask, characterized in that, It includes an inner surface layer, a filling layer and an outer surface layer from the inside out; The inner surface layer, the filling layer and the outer surface layer are all made of non-woven fabric. The porosity of the outer surface layer is 0.7 - 0.9 times that of the inner surface layer, and / or the fiber diameter of the outer surface layer is 0.7 - 0.9 times that of the inner surface layer; The filling layer includes a first base layer formed by first fibers and a hydrogen-producing material loaded in the first base layer. The hydrogen-producing material includes silicon powder and metal powder. The metal powder is magnesium powder, zinc powder or a combination of magnesium powder and zinc powder; in the filling layer, the loading mass percentage of silicon powder is 5 - 10%, and the loading percentage of the metal powder is 2.5 - 5%; The inner surface layer at least includes a second base layer and phospholipids loaded in the second base layer.

2. The antioxidant facial mask for transdermal hydrogen injection according to claim 1, characterized in that, In the filling layer, the metal powder is a mixture of zinc powder and magnesium powder, and the mass ratio of zinc powder to magnesium powder is 1∶6 - 15. It also includes magnesium hydroxide, and the mass of magnesium hydroxide is 2 - 5 times the mass of the metal powder, and the loading mass percentage is not higher than 20%.

3. The antioxidant facial mask for transdermal hydrogen injection according to claim 2, characterized in that, The filling layer also includes sodium bicarbonate, and the loading mass percentage of sodium bicarbonate is 15 - 25%.

4. The antioxidant facial mask for transdermal hydrogen injection according to claim 2, characterized in that, In the filling layer, sodium alginate is also included, and the loading mass percentage of sodium alginate is 1 - 3%.

5. The antioxidant facial mask for transdermal hydrogen injection according to claim 2, wherein The first fibers are a combination of modal fibers and viscose fibers, and the mass ratio of modal fibers to viscose fibers is 1∶0.2 - 0.

3.

6. The antioxidant facial mask for transdermal hydrogen injection according to claim 5, wherein The ratio of the particle size of the silicon powder to the diameter of the first fibers is 0.1 - 0.8∶1.

7. The antioxidant facial mask for transdermal hydrogen injection according to claim 1, wherein The inner surface layer is a modal fiber non-woven fabric.

8. The antioxidant facial mask for transdermal hydrogen injection according to claim 1, wherein The outer surface layer is a combination of cotton fibers and PET fibers, and the mass ratio of cotton fibers to PET fibers is 1∶0.2 - 0.

5.

9. The antioxidant facial mask for transdermal hydrogen injection according to claim 1, characterized in that, It also includes a wetting agent for wetting the inner surface layer, the filling layer and the outer surface layer before use. The wetting agent is a water-glycerol mixed system.

10. The preparation method of the transdermal absorption hydrogen injection antioxidant facial mask according to any one of claims 1 to 9, characterized in that It includes the following steps: S1. Preparation of materials: Configure the inner surface layer, the first base layer and the second base layer, and weigh the required loading system; S2. Crushing: Crush the materials in the filling layer except the first base layer, and screen out large particles; S3. Mixing: Mix the raw materials crushed in S2 with water at a mass concentration of 5 - 30% to obtain a first mixture; dissolve phospholipids in water to prepare a second mixture; in the second mixture, the mass ratio of phospholipids to the second base layer is 0.01 - 0.05∶1; S4. Coating: Coat the first mixture on the first base layer, and coat the second mixture on the second base layer; S5. Hot pressing: Stack the inner surface layer, the filling layer and the outer surface layer, and make the side of the inner surface layer coated with the second mixture fit with the side of the filling layer coated with the first mixture. Then, perform hot pressing under wet conditions. The hot pressing temperature is 300 - 400°C, the pressure is 2 - 4t, and the contact time is 1 - 5s; S6. Disinfection and packaging.

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