Traditional Chinese medicine composition for treating cervical spondylotic radiculopathy and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for treating cervical spondylotic radiculopathy and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20 to 40 parts of radix puerariae, 5 to 25 parts of cassia twig, 20 to 40 parts of ramulus mori, 5 to 25 parts of notopterygium root, 20 to 40 parts of radix astragali seu hedysari, 20 to 40 parts of radix salviae miltiorrhizae, 5 to 25 parts of rhizoma chuanxiong, 5 to 25 parts of radix angelicae sinensis, 20 to 40 parts of radix paeoniae alba, 5 to 25 parts of radix clematidis, 5 to 20 parts of radix notoginseng, 2 to 10 parts of flos carthami, 5 to 25 parts of fructus chaenomelis lagenariae, 5 to 25 parts of earthworm, 20 to 40 parts of caulis spatholobi and 5 to 25 parts of pericarpium citri reticulatae. The traditional Chinese medicine composition disclosed by the invention is precise and reasonable in formula, standard and feasible in preparation process, free of any hormone, preservative and additive, and high in safety as natural raw materials are selected.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine compositions, and specifically relates to a traditional Chinese medicine composition for treating nerve root type cervical spondylosis and a preparation method thereof. Background Art

[0002] Cervical spondylosis, also known as cervical syndrome, is a series of degenerative changes and secondary changes that occur in the cervical intervertebral disc (degeneration), cervical bone joints (bone hyperplasia), and their related muscles, ligaments, and fascia (strain), which stimulate or compress the surrounding spinal cord, nerves, blood vessels and other tissues, resulting in a series of clinical symptoms and signs. Among various types of cervical spondylosis, nerve root type is the most common and has the highest incidence rate. Nerve root type is manifested by irritation or compression of the cervical nerve roots, mainly characterized by soreness and numbness in the upper limbs.

[0003] Due to the popularization of electronic products such as computers and mobile phones, the accelerating pace of modern life, and the change of working methods, as well as bad postures, the incidence rate of nerve root type cervical spondylosis is increasing continuously and is getting younger and younger. The harm of cervical spondylosis is far more than just pain. It also seriously affects the quality of life of patients and threatens human health.

[0004] At present, the conventional Western medicine treatment for nerve root type cervical spondylosis is either surgical treatment according to its specific etiology or drug treatment such as non-steroidal anti-inflammatory drugs, painkillers, and local blockades for symptoms. Surgery causes greater damage to the body and fails to solve the biomechanical etiology well, and the long-term curative effect is generally average. Drugs only relieve the symptoms but do not address the root cause, and have a greater impact on gastrointestinal function. Patients are resistant to taking them for a long time.

[0005] Nerve root type cervical spondylosis belongs to the category of bi-syndrome in traditional Chinese medicine. Traditional Chinese medicine believes that the deficiency of healthy qi and insufficiency of qi and blood are the root cause, while the mutual binding of phlegm and stasis is the superficial cause. However, at present, the same prescription is mostly used to treat different types of cervical spondylosis, without corresponding treatment for different types of cervical spondylosis, resulting in a greatly reduced curative effect.

[0006] Chinese Patent with the publication number CN115607591A discloses a traditional Chinese medicine composition for treating cervical / lumbar intervertebral disc / rheumatic bi-syndrome and a preparation method thereof. By adding Strychnos nux-vomica, Glycyrrhiza uralensis, Olibanum, Myrrha, Cyathula officinalis, Aconitum kusnezoffii, Ephedra sinica, Eupolyphaga sinensis, Atractylodes lancea, Bombyx batryticatus, Scorpio, Aconitum carmichaelii, the finished product has the effects of promoting blood circulation to remove blood stasis, dispelling wind and dampness, dredging meridians and collaterals, strengthening tendons and bones, reducing swelling and relieving pain, enhancing muscle tension, nourishing nerves and restoring nerve function.

[0007] However, in the above traditional Chinese medicine formula, there are components with relatively strong toxicity such as Aconitum carmichaelii and Aconitum kusnezoffii, which have cardiac toxicity, neurotoxicity, and skin toxicity, and have relatively high side effects. In addition, in the prior art, treatment methods such as massage, traction, physical therapy, acupuncture, small needle knife, and surgery are also used. Although these methods can relieve symptoms temporarily, they are prone to recurrence after treatment is stopped. Therefore, drugs and their preparations for treating nerve root type cervical spondylosis that treat both the symptoms and the root cause are urgently in need of improvement and innovation. Summary of the Invention

[0008] The purpose of the present invention is to provide a traditional Chinese medicine composition for treating nerve root type cervical spondylosis and its preparation method, so as to solve the problems raised in the above background technology.

[0009] To achieve the above purpose, the technical solution of the present invention is a traditional Chinese medicine composition for treating nerve root type cervical spondylosis, which includes raw materials composed of the following parts by weight: 20-40 parts of Pueraria lobata, 5-25 parts of Cinnamomum cassia, 20-40 parts of Ramulus mori, 5-25 parts of Notopterygium incisum, 20-40 parts of Astragalus membranaceus, 20-40 parts of Salvia miltiorrhiza, 5-25 parts of Ligusticum chuanxiong, 5-25 parts of Angelica sinensis, 20-40 parts of Paeonia lactiflora, 5-25 parts of Clematis chinensis, 5-20 parts of Panax notoginseng, 2-10 parts of Carthamus tinctorius, 5-25 parts of Chaenomeles sinensis, 5-25 parts of Pheretima aspergillum, 20-40 parts of Spatholobus suberectus, and 5-25 parts of Citrus reticulata Blanco.

[0010] Preferably, it includes raw materials composed of the following parts by weight: 30 parts of Pueraria lobata, 15 parts of Cinnamomum cassia, 30 parts of Ramulus mori, 15 parts of Notopterygium incisum, 30 parts of Astragalus membranaceus, 30 parts of Salvia miltiorrhiza, 15 parts of Ligusticum chuanxiong, 15 parts of Angelica sinensis, 30 parts of Paeonia lactiflora, 15 parts of Clematis chinensis, 10 parts of Panax notoginseng, 6 parts of Carthamus tinctorius, 15 parts of Chaenomeles sinensis, 15 parts of Pheretima aspergillum, 30 parts of Spatholobus suberectus, and 15 parts of Citrus reticulata Blanco.

[0011] A preparation method of a traditional Chinese medicine composition for treating nerve root type cervical spondylosis includes the following steps:

[0012] S1: Selection and cleaning of raw materials: Select high-quality genuine traditional Chinese medicine raw materials without pests and diseases, soak and clean them with clean water, and then dry them for standby;

[0013] S2: Extraction and treatment of raw materials: Add the dried Pueraria lobata, Cinnamomum cassia, Ramulus mori, Notopterygium incisum, Astragalus membranaceus, Salvia miltiorrhiza, Ligusticum chuanxiong, Angelica sinensis, Paeonia lactiflora, Clematis chinensis, Panax notoginseng, Carthamus tinctorius, Chaenomeles sinensis, Pheretima aspergillum, Spatholobus suberectus, Citrus reticulata Blanco, etc. into a container in sequence, add 4-5 times of distilled water, steam for 2-3 hours, collect the steaming liquid, then add 3-4 times of distilled water into the container, steam for 1.5-2 hours, collect the steaming liquid, continue to add 1-2 times of distilled water into the container, steam for 1-1.5 hours, collect the steaming liquid, mix the steaming liquids collected three times, and then heat and dry them to obtain a powdery extract for standby;

[0014] S3: Grinding treatment of raw materials: Dry the dried earthworms and notopterygium roots, remove the moisture, and then add the earthworms and notopterygium roots to a grinding device to grind them into powder for standby;

[0015] S4: Mix and stir evenly the powdered raw materials obtained in S2 and S3 to obtain a traditional Chinese medicine composition for treating nerve root type cervical spondylosis.

[0016] Preferably, the traditional Chinese medicine mixture obtained in S4 can be used to prepare pills, tablets or capsules respectively.

[0017] Preferably, the preparation of the traditional Chinese medicine composition is carried out in a sterile preparation workshop.

[0018] Applicable population: Except for pregnant women, the rest of the population with symptoms such as chronic cervical spondylosis, lumbar spondylosis or neck and low back pain can use it.

[0019] Dosage method: Take the medicine twice a day, and the dosage of one dose of the medicine contains 5 grams of the traditional Chinese medicine mixture. One month is a course of treatment, and the patient takes three courses of treatment.

[0020] Shelf life: 1 year; It can be stored at room temperature; Please consume it within one year after opening.

[0021] Precautions: 1. It is contraindicated during menstruation and pregnancy for women.

[0022] 2. It is contraindicated for colds, fevers, sore throats, diarrhea, etc.

[0023] 3. Avoid staying up late, drinking alcohol, and eating sweet foods during the medication period.

[0024] Pharmacological effects of the above traditional Chinese medicine:

[0025] Pueraria lobata: Sweet, pungent, and cool in nature. It belongs to the spleen, stomach, and lung meridians. In "Treatise on Febrile Diseases": "For the syndrome of Taiyang disease with stiffness and pain in the nape and back, aversion to wind with sweating, Cinnamon Twig Decoction plus Pueraria Lobata is the main prescription." Pueraria lobata is sweet, pungent, light, and ascending and dispersing, relieving the stiffness and pain in the nape and back. As a guiding drug, it reaches the affected area directly. It can be used regardless of cold, heat, deficiency, or excess, with or without sweating. This product contains flavonoid components, coumarin components, puerarin, pueraria vine element, isoflavone glycosides, starch and other components.

[0026] Cinnamon twig: Pungent, sweet, and warm in nature. It belongs to the heart, lung, and bladder meridians. Cinnamon twig is pungent and dispersing, warm and dredging, walking through the four limbs, sweet and warm in helping yang, warm and dredging and flowing smoothly, with the effect of "dispelling pathogenic cold, dredging the blood vessels, and stopping pain". It enters both the qi aspect and the blood aspect, and is suitable for blood stasis with cold. This product contains volatile oil, phenols, organic acids, polysaccharides, glycosides, coumarin, tannins and other components.

[0027] Mulberry Twig: Slightly bitter in taste, neutral in nature, and attributive to the Liver Meridian, it has the effects of dispelling wind-dampness and promoting joint movement. It can dispel wind-dampness and promote joint movement, and is good at treating wind-damp arthralgia syndrome. It can be applied to both new and long-standing, cold and heat arthralgia syndromes. It can reach the meridians of the four limbs well, especially good at treating upper limb diseases, and is suitable for those with soreness, numbness in the shoulders, arms and joints.

[0028] Notopterygium Root: Pungent, bitter and warm in nature. Attributive to the Bladder and Kidney Meridians. Notopterygium Root is pungent for dispersing, bitter for drying dampness, warm for dredging and ascending and dispersing. Its qi is strong and intense. It mainly enters the Bladder Meridian and also enters the Kidney Meridian. It is mainly for the exterior and the upper part, dispersing wandering wind and cold-dampness in the exterior and dredging and promoting joint movement to relieve pain. Its power is relatively strong, and it is good at treating neck pain, especially pain in the shoulders, back and limb joints. Notopterygium Root was first used in the Han Dynasty and was mixed with Angelica Pubescens. It was not until "Materia Medica of Medicinal Properties" in the Tang Dynasty that the two were listed separately. This product mainly contains volatile oils: α-thujene, α-pinene, β-pinene, etc.; coumarins: nodakenin, notopterol, isoimperatorin, 8-methylisoimperatorin; phenolic components: xanthotoxol.

[0029] Astragalus Root: Sweet and slightly warm in nature, attributive to the Spleen and Lung Meridians. It mainly tonifies the healthy qi and can also eliminate water pathogen. It is not only good at tonifying the middle qi and lifting the clear yang, but also good at tonifying the lung qi and strengthening the exterior to secure the superficies. By tonifying qi, it can also generate blood, arrest bleeding, promote the production of body fluid and promote qi movement. It can treat arthralgia, numbness and hemiplegia caused by qi deficiency and blood stasis.

[0030] Salvia Miltiorrhiza: Bitter in taste, slightly cold in nature, attributive to the Heart and Liver Meridians. It can activate blood circulation to remove stasis, dredge the channels and relieve pain, and is mainly used to treat various syndromes of blood stasis, blood heat and heat disturbing the mind. It is said in ancient times that "a single dose of Salvia Miltiorrhiza powder has the same effect as the Four Substances Decoction". It is actually a product for cooling blood and activating blood circulation, removing stasis and generating new blood. This product contains quinone components, protocatechualdehyde, protocatechuic acid, lactic acid, vitamin E and other components.

[0031] Chuanxiong Rhizome: Pungent and warm in nature. Attributive to the Liver, Gallbladder and Pericardium Meridians. Chuanxiong Rhizome is pungent, fragrant, dispersing, warm and dredging. It ascends to the vertex of the head, descends to the blood sea, moves qi and blood internally and disperses wind-cold externally. Its blood-activating power is strong. It can treat various pains caused by blood stasis and qi stagnation, especially suitable for those with cold. It was praised by predecessors as "the qi drug in blood". It can treat various headaches, especially those caused by wind-cold and blood stasis. Therefore, there is a saying among predecessors that "headache is inseparable from Chuanxiong Rhizome". This product contains alkaloids, volatile oils, phenolic substances, lactones, as well as vitamin A, folic acid, sucrose, sterols, fatty oils and other components.

[0032] Angelica Sinensis: Sweet, pungent in taste, warm in nature, attributive to the Liver, Heart and Spleen Meridians. Angelica Sinensis is sweet for nourishing and moistening, pungent and warm for promoting qi movement and dispersing. It is good at nourishing blood and activating blood circulation, regulating menstruation and relieving pain, moistening the intestines and promoting defecation, and can dispel cold. It is suitable for all syndromes of blood deficiency, blood stasis with cold, especially those with dryness of the intestines and constipation. It is not only the key drug for regulating menstruation in gynecology, but also an excellent product for nourishing blood. There is a saying that "nine out of ten blood-nourishing prescriptions contain Angelica Sinensis" in blood-nourishing prescriptions. It mainly contains volatile oils such as ligustilide, angelicone, p-cymenene, butylidenephthalide, verbenone, safrole, and organic acid components such as ferulic acid, vanillic acid, nicotinic acid, succinic acid, and also contains angelica polysaccharide, amino acids, vitamin A and other components.

[0033] White Peony Root: Bitter, sour in taste, slightly cold in nature. It acts on the liver and spleen meridians. This herb can relieve spasm and pain, soften the hardness and firmness, and has the effect of softening bone spurs. It is used for symptoms such as sallow complexion due to blood deficiency, spasmodic pain in the limbs, hyperactivity of liver yang, headache and dizziness. It mainly contains monoterpenoids, sterols, tannins, phenols and other components.

[0034] Clematis Root: Pungent, salty in taste, warm in nature. It acts on the bladder meridian. Clematis root is pungent, dispersing, salty, softening, warm and dredging, entering the bladder meridian (or said to enter the twelve meridians), and has the effects of dispelling wind-dampness and dredging collaterals. It is good at moving around, with strong power and quick effect. It is most suitable for those with wind-dampness arthralgia, contracture and numbness, difficulty in flexion and extension, and accompanied by cold. Clematis root contains protooleanolic acid, hederagenin, protoanemonin, palmitic acid and other components.

[0035] Notoginseng: Sweet, slightly bitter in taste, warm in nature. It acts on the liver and stomach meridians. Notoginseng is slightly bitter and dispersing, sweet and tonifying, warm and dredging, with both moving and astringing properties, and has the effects of dissipating stasis and stopping bleeding, reducing swelling and relieving pain. It has strong effects on both hemostasis and promoting blood circulation to remove stasis, and can also tonify deficiency, with the advantages of stopping bleeding without leaving stasis and promoting blood circulation without consuming qi. It is effective both orally and topically, and is most suitable for those with cold syndrome and deficiency. It mainly contains tetracyclic triterpenoid components such as ginsenosides, notoginsenosides, and gypenosides, and also contains dencichine, quercetin and polysaccharides and other substances.

[0036] Safflower: Pungent, warm in nature. It acts on the heart and liver meridians. Safflower is pungent, dispersing, warm and dredging. It is good at promoting blood circulation to remove stasis, dredging channels to reduce swelling and relieve pain, with strong medicinal power. It can be used for various syndromes of blood stasis, and is most suitable for those with cold syndrome. This herb contains flavonoid components, phenolic components, fatty acid components, volatile components, etc.

[0037] Chaenomeles Fruit: Sour in taste, warm in nature. It acts on the liver and spleen meridians. Sour taste enters the liver and can relax tendons and activate collaterals, being good at treating wind-dampness arthralgia and tendon contracture.

[0038] Earthworm: Salty in taste, cold in nature. It acts on the liver, spleen and bladder meridians. Earthworm has the effect of dredging collaterals, being able to promote blood circulation, dredge channels, and improve symptoms such as hemiplegia, limb numbness, and joint pain.

[0039] Caulis Spatholobi: Bitter, sweet in taste, warm in nature. It acts on the liver and kidney meridians. It has a slight smell and astringent taste. Caulis Spatholobi is bitter, dispersing, warm and dredging, slightly sweet and tonifying, entering the liver and kidney meridians. It can both promote blood circulation to dredge collaterals and relieve pain, and nourish blood and soothe tendons and relieve pain. It can be used for various syndromes of blood stasis and blood deficiency with cold. It is most suitable for those with numbness and pain due to blood deficiency and arthralgia. It contains steroid compounds, isoflavonoid compounds and triterpenoid compounds, etc.

[0040] Dried Tangerine Peel: Bitter, pungent in taste, warm in nature. It acts on the lung and spleen meridians. Dried Tangerine Peel is pungent, fragrant, dispersing, bitter, drying and warm in nature, entering the spleen and lung meridians. It can both regulate the qi movement of the spleen and lung to regulate the middle energizer, and dry dampness and regulate qi to resolve phlegm turbidity. It can be used for all syndromes of qi stagnation, damp obstruction and phlegm congestion. It mainly contains volatile oils, hesperidin, nobiletin and vitamins B and C, etc.

[0041] This invention was developed by a team consisting of veteran traditional Chinese medicine practitioners and medical doctors during decades of clinical practice in treating cervical spondylosis. It was found that nerve root type cervical spondylosis accounts for more than half. Aiming at the deficiencies in the current treatments of nerve root type cervical spondylosis pain by Western medicine and traditional Chinese medicine, it is made by taking replenishing qi and blood as the foundation and relaxing tendons and dredging collaterals as the goal, and selecting drugs such as Pueraria lobata, Cinnamomum cassia, Ramulus mori, Notopterygium incisum, Panax notoginseng, etc., and scientifically proportioning them to form a prescription.

[0042] The beneficial effects of this invention are as follows:

[0043] The traditional Chinese medicine composition for treating nerve root type cervical spondylosis provided by this invention has the characteristics of good treatment effect, quick onset of effect, and small side effects. The formula of this invention is precise and reasonable, the production process is standardized and easy to operate, it does not contain any hormones, preservatives, or additives, and natural raw materials are selected, with high safety. Specific implementation mode

[0044] The following further illustrates this invention in combination with embodiments.

[0045] Embodiment 1: A traditional Chinese medicine composition for treating nerve root type cervical spondylosis, comprising raw materials composed of the following parts by weight: 20 parts of Pueraria lobata, 5 parts of Cinnamomum cassia, 20 parts of Ramulus mori, 5 parts of Notopterygium incisum, 20 parts of Astragalus membranaceus, 20 parts of Salvia miltiorrhiza, 5 parts of Ligusticum chuanxiong, 5 parts of Angelica sinensis, 20 parts of Paeonia lactiflora, 5 parts of Clematis chinensis, 5 parts of Panax notoginseng, 2 parts of Carthamus tinctorius, 5 parts of Chaenomeles sinensis, 5 parts of Pheretima aspergillum, 20 parts of Spatholobus suberectus, and 5 parts of Citrus reticulata Blanco.

[0046] A preparation method of a traditional Chinese medicine composition for treating nerve root type cervical spondylosis comprises the following steps:

[0047] S1: Selection and cleaning of raw materials: Select high-quality genuine traditional Chinese medicine raw materials without pests and diseases, soak and clean them with clean water, and then dry them for later use;

[0048] S2: Extraction treatment of raw materials: Add the dried Pueraria lobata, Cinnamomum cassia, Ramulus mori, Notopterygium incisum, Astragalus membranaceus, Salvia miltiorrhiza, Ligusticum chuanxiong, Angelica sinensis, Paeonia lactiflora, Clematis chinensis, Panax notoginseng, Carthamus tinctorius, Chaenomeles sinensis, Pheretima aspergillum, Spatholobus suberectus, Citrus reticulata Blanco, etc. into a container in sequence, add 4 times the amount of distilled water, steam for 2 hours, collect the steaming liquid, then add 3 times the amount of distilled water to the container, steam for 1.5 hours, collect the steaming liquid, continue to add 1 time the amount of distilled water to the container, steam for 1 hour, collect the steaming liquid, mix the steaming liquids collected three times, and then heat and dry them to obtain a powdery extract for later use;

[0049] S3: Grinding treatment of raw materials: Dry the dried Pheretima aspergillum and Notopterygium incisum to remove moisture, and then add the Pheretima aspergillum and Notopterygium incisum to a grinding device to grind them into powder for later use;

[0050] S4: Mix and stir evenly the powdery raw materials obtained in S2 and S3 to obtain a traditional Chinese medicine composition for treating nerve root type cervical spondylosis.

[0051] The traditional Chinese medicine mixture prepared in S4 is made into pills in an aseptic preparation workshop.

[0052] Case 1: Name: Li XX, Gender: Male, Age: 31, Occupation: Accountant

[0053] First diagnosis time: November 24, 2020

[0054] Chief complaint: Numbness and pain in the right upper limb and neck stiffness for more than 1 month.

[0055] Present illness history: The patient reported that one month ago, pain in the right upper limb and pain in the upper inner corner of the right scapula began to occur when using the computer. He went to the outpatient department of a certain hospital in Shenzhen. After X-ray examination, it was found that the physiological curvature of the cervical spine was straightened, and the intervertebral spaces of C4 / 5 and C5 / 6 were narrowed. For further clear diagnosis, MR examination was performed, and it was found that the discs of C4 / 5 and C5 / 6 protruded, diagnosed as nerve root type cervical spondylosis. After taking anti-inflammatory, analgesic and hormone drugs, there was no obvious improvement. Due to taking western medicine for a long time, it caused indigestion and often woke up in pain in the middle of the night. He came to our department for treatment.

[0056] Physical examination: Distressed appearance, numbness and pain from the right upper limb to the thumb and index finger, obvious tenderness in the right C4, C5, and C6 small joints, loose stools, normal urine, red tongue with thin white coating, and string-like pulse.

[0057] Past medical history: Previously in good health, denied major trauma history.

[0058] Specialist examination: Neck muscle tension (+), tenderness left (-) / right (+), limited neck movement, forward flexion (++) / extension (+) / left rotation (+) / right rotation (++) / left lateral flexion (-) / right lateral flexion (+) with decreased range of motion (+), percussion test (-), brachial plexus traction test left (-) / right (+), compression test (Spurling test) (-), Hoffmann sign (-).

[0059] Auxiliary examination:

[0060] Cervical spine X-ray film: The physiological curvature of the cervical spine is straightened, the bilateral C4 / 5 and C5 / 6 intervertebral spaces are narrowed, and the nuchal ligament calcification is (+).

[0061] Cervical spine MR: The discs of C4 / 5 and C5 / 6 protrude.

[0062] Diagnosis:

[0063] Traditional Chinese medicine: Neck Bi disease (Qi stagnation and blood stasis type)

[0064] Western medicine: Nerve root type cervical spondylosis

[0065] Treatment: Take the self-prepared medicine, about 5 grams each time, twice a day. One month is a treatment course. After one month, go for a follow-up visit. The patient reported that symptoms such as numbness and pain in the upper limbs and limited neck movement were alleviated. Continue to take the second treatment course. During the second follow-up visit, the patient reported that the numbness in the upper limbs was significantly improved and the neck movement was basically normal. Take the third treatment course. The patient reported that all symptoms basically disappeared. It is recommended to take one more treatment course for consolidation.

[0066] Example 2: A traditional Chinese medicine composition for treating nerve root type cervical spondylosis, comprising raw materials in the following parts by weight: 30 parts of Pueraria lobata, 15 parts of Cinnamomum cassia, 30 parts of Mori Ramulus, 15 parts of Notopterygium incisum, 30 parts of Astragalus membranaceus, 30 parts of Salvia miltiorrhiza, 15 parts of Ligusticum chuanxiong, 15 parts of Angelica sinensis, 30 parts of Paeonia lactiflora, 15 parts of Clematis chinensis, 10 parts of Panax notoginseng, 6 parts of Carthamus tinctorius, 15 parts of Chaenomeles sinensis, 15 parts of Pheretima aspergillum, 30 parts of Spatholobus suberectus and 15 parts of Citrus reticulata Blanco.

[0067] A preparation method of a traditional Chinese medicine composition for treating nerve root type cervical spondylosis, comprising the following steps:

[0068] S1: Selection and cleaning of raw materials: Select genuine traditional Chinese medicine raw materials with good appearance and no pests and diseases, soak and clean them with clean water, and then dry them for standby;

[0069] S2: Extraction treatment of raw materials: Add the dried Pueraria lobata, Cinnamomum cassia, Mori Ramulus, Notopterygium incisum, Astragalus membranaceus, Salvia miltiorrhiza, Ligusticum chuanxiong, Angelica sinensis, Paeonia lactiflora, Clematis chinensis, Panax notoginseng, Carthamus tinctorius, Chaenomeles sinensis, Pheretima aspergillum, Spatholobus suberectus, Citrus reticulata Blanco, etc. into a container in sequence, add 4.5 times of distilled water, steam for 2.5 hours, collect the steaming liquid, then add 3.5 times of distilled water to the container, steam for 1.5 hours, collect the steaming liquid, continue to add 1.5 times of distilled water to the container, steam for 1 hour, collect the steaming liquid, mix the steaming liquids collected three times, and then heat and dry to obtain a powdery extract for standby;

[0070] S3: Grinding treatment of raw materials: Dry the dried Pheretima aspergillum and Notopterygium incisum to remove moisture, and then add the Pheretima aspergillum and Notopterygium incisum to a grinding device to grind them into powder for standby;

[0071] S4: Mix and stir evenly the powdery raw materials prepared in S2 and S3 to obtain a traditional Chinese medicine composition for treating nerve root type cervical spondylosis.

[0072] The traditional Chinese medicine mixture prepared in S4 is prepared into tablets in a sterile preparation workshop.

[0073] Case 2: Name: Li XX Gender: Female Age: 49 Occupation: Company employee

[0074] First diagnosis time: July 28, 2022

[0075] Chief complaint: Neck soreness, numbness and pain in the left upper limb and shoulder for more than 1 year.

[0076] Present illness history: The patient reported that one year ago, after being fatigued from work, there was soreness and discomfort in the neck, and numbness and pain in the left upper limb. The patient had visited a certain hospital in Guangzhou and a certain hospital in Shenzhen. After MR examination: There were herniations / bulges of the C3 / 4, C4 / 5, C5 / 6, and C6 / 7 intervertebral discs, cervical hyperplasia, calcification of the nuchal ligament, and the treatment effect was not obvious. Now the patient comes for traditional Chinese medicine treatment.

[0077] Physical examination: The complexion was sallow, the spirit was fatigued, there was palpitation, restlessness, difficulty in falling asleep, poor appetite, clear and frequent urination, loose stools, the tongue was dull with a thin white coating, and the pulse was thready and weak.

[0078] Past history: The patient had been in good health and denied any history of major trauma.

[0079] Specialist examination:

[0080] The nuchal muscles were tense (+), there was tenderness on the left side (+) / right side (-), neck movement was restricted, forward flexion (+) / extension (+) / left rotation (++) / right rotation (++) / left lateral flexion (+) / right lateral flexion (+) with a decrease in range of motion (+), the brachial plexus traction test was positive on the left side (+) / right side (-), the cervical compression test (Spurling test) was negative (-), the Hoffmann sign was negative (-), and there was decreased pain sensation in the outer side of the left upper arm, forearm, thenar eminence, and fingers.

[0081] Auxiliary examination:

[0082] Cervical spine X-ray: The physiological curvature was straightened, there was osteophyte formation on the 3rd, 4th, and 5th cervical vertebrae, and the bilateral uncovertebral joints of C3, C4, and C5 became pointed.

[0083] Cervical spine MR: (C3 / 4, C4 / 5, C5 / 6, C6 / 7) intervertebral disc herniation / bulge, cervical hyperplasia, and calcification of the nuchal ligament.

[0084] Diagnosis:

[0085] Traditional Chinese medicine: Neck Bi (Qi deficiency and blood stasis type)

[0086] Western medicine: Radiculopathic type of cervical spondylosis

[0087] Treatment: Take the self-made medicine, about 5 grams each time, twice a day, and one month is a course of treatment. After one month of follow-up, the patient reported that symptoms such as numbness and pain in the left upper limb and soreness in the neck were relieved. Continue to take the second course of treatment. At the second follow-up, the patient reported that the numbness and pain in the left upper limb were significantly improved, and neck movement was basically normal. Take the third course of treatment. The patient reported good sleep, everything was normal, the appetite was acceptable, and bowel and bladder movements were normal. It is recommended to take one more course of treatment for consolidation.

[0088] Example 3: A traditional Chinese medicine composition for treating nerve root type cervical spondylosis, comprising raw materials in the following parts by weight: 40 parts of kudzu root, 25 parts of cassia twig, 40 parts of mulberry twig, 25 parts of notopterygium root, 40 parts of astragalus membranaceus, 40 parts of salvia miltiorrhiza, 25 parts of ligusticum wallichii, 25 parts of angelica sinensis, 40 parts of white peony root, 25 parts of clematis chinensis, 20 parts of notoginseng, 10 parts of safflower, 25 parts of papaya, 25 parts of pheretima, 40 parts of millettia reticulata and 25 parts of dried tangerine peel.

[0089] A preparation method of a traditional Chinese medicine composition for treating nerve root type cervical spondylosis, comprising the following steps:

[0090] S1: Raw material selection and cleaning: Select genuine traditional Chinese medicine raw materials with good appearance and no pests or diseases, soak and clean them with clean water, and then dry them for standby;

[0091] S2: Raw material extraction treatment: Add the dried kudzu root, cassia twig, mulberry twig, notopterygium root, astragalus membranaceus, salvia miltiorrhiza, ligusticum wallichii, angelica sinensis, white peony root, clematis chinensis, notoginseng, safflower, papaya, pheretima, millettia reticulata, dried tangerine peel, etc. into a container in sequence, add 5 times of distilled water, cook for 3 hours, collect the cooking liquid, then add 4 times of distilled water into the container, cook for 2 hours, collect the cooking liquid, continue to add 2 times of distilled water into the container, cook for 1.5 hours, collect the cooking liquid, mix the cooking liquids collected three times, and then heat and dry them to obtain a powdery extract for standby;

[0092] S3: Raw material grinding treatment: Dry the dried pheretima and notopterygium root to remove moisture, and then add the pheretima and notopterygium root into a grinding device to grind them into powder for standby;

[0093] S4: Mix and stir evenly the powdery raw materials obtained in S2 and S3 to obtain a traditional Chinese medicine composition for treating nerve root type cervical spondylosis.

[0094] The traditional Chinese medicine mixture obtained in S4 is prepared into a capsule medicine in a sterile preparation workshop.

[0095] The above embodiments are only used to illustrate the technical concept and characteristics of the present invention, and the purpose is to enable those who are familiar with this technology to understand the content of the present invention and implement it accordingly, and it cannot be used to limit the protection scope of the present invention. Any equivalent changes or modifications made according to the spirit and essence of the present invention should be covered within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for treating nerve root type cervical spondylosis, characterized in that, It comprises raw materials in the following parts by weight: 20 - 40 parts of kudzu root, 5 - 25 parts of cassia twig, 20 - 40 parts of mulberry twig, 5 - 25 parts of notopterygium root, 20 - 40 parts of astragalus root, 20 - 40 parts of salvia root, 5 - 25 parts of ligusticum wallichii, 5 - 25 parts of angelica sinensis, 20 - 40 parts of white peony root, 5 - 25 parts of clematis root, 5 - 20 parts of panax notoginseng, 2 - 10 parts of safflower, 5 - 25 parts of chaenomeles fruit, 5 - 25 parts of pheretima, 20 - 40 parts of millettia reticulata benth. and 5 - 25 parts of dried tangerine peel.

2. The traditional Chinese medicine composition for treating nerve root type cervical spondylosis according to claim 1, wherein It comprises raw materials in the following parts by weight: 30 parts of kudzu root, 15 parts of cassia twig, 30 parts of mulberry twig, 15 parts of notopterygium root, 30 parts of astragalus root, 30 parts of salvia root, 15 parts of ligusticum wallichii, 15 parts of angelica sinensis, 30 parts of white peony root, 15 parts of clematis root, 10 parts of panax notoginseng, 6 parts of safflower, 15 parts of chaenomeles fruit, 15 parts of pheretima, 30 parts of millettia reticulata benth. and 15 parts of dried tangerine peel.

3. The preparation method of a traditional Chinese medicine composition for treating nerve root type cervical spondylosis according to claim 1, characterized in that, It comprises the following steps: S1: Raw material selection and cleaning: Select genuine regional traditional Chinese medicine raw materials with good appearance and no pests or diseases, soak and clean them with clear water, and then dry them for standby; S2: Raw material extraction treatment: Add the dried kudzu root, cassia twig, mulberry twig, notopterygium root, astragalus root, salvia root, ligusticum wallichii, angelica sinensis, white peony root, clematis root, panax notoginseng, safflower, chaenomeles fruit, pheretima, millettia reticulata benth., dried tangerine peel, etc. into a container in sequence, add 4 - 5 times of distilled water, cook for 2 - 3 hours, collect the cooking liquid, then add 3 - 4 times of distilled water into the container, cook for 1.5 - 2 hours, collect the cooking liquid, continue to add 1 - 2 times of distilled water into the container, cook for 1 - 1.5 hours, collect the cooking liquid, mix the cooking liquids collected three times, and then heat and dry to obtain a powdery extract for standby; S3: Raw material grinding treatment: Dry the dried pheretima and notopterygium root to remove moisture, and then add the pheretima and notopterygium root into a grinding device to grind them into powder for standby; S4: Mix and stir evenly the powdery raw materials prepared in S2 and S3 to obtain a traditional Chinese medicine composition for treating nerve root type cervical spondylosis.

4. The preparation method of a traditional Chinese medicine composition for treating nerve root type cervical spondylosis according to claim 3, characterized in that, The traditional Chinese medicine mixture prepared in S4 can be respectively used for preparing pills, tablets or capsules.

5. The preparation method of a traditional Chinese medicine composition for treating nerve root type cervical spondylosis according to claim 3, wherein, The preparation of the traditional Chinese medicine composition is carried out in a sterile preparation workshop.