Composition with improved water resistance

Abstract

The present invention relates to a sunscreen product, a cosmetic or pharmaceutical formulation or a home care product comprising at least one predominant organic and / or inorganic UV filter, a mycosporine amino acid compound of a certain kind and optionally at least one film-forming agent. These products and formulations provide improved water resistance, and thus improve SPF performance, without creating unpleasant stickiness. Furthermore, the present invention relates to the use of such mycosporine amino acid compounds for improving the water resistance and thus SPF performance of a sunscreen product, a cosmetic or pharmaceutical formulation or a home care product, the sunscreen product, cosmetic or pharmaceutical formulation or home care product comprises at least one predominant organic and / or inorganic UV filter and optionally at least one film-forming agent. Finally, the invention relates to a method for increasing the water resistance and thus SPF performance of a sunscreen product, a cosmetic or pharmaceutical formulation or a home care product by adding a certain kind of mycosporine amino acid compounds, the sunscreen product, cosmetic or pharmaceutical formulation or home care product comprises at least one predominant organic and / or inorganic UV filter and optionally at least one film-forming agent.

Description

TECHNICAL FIELD

[0001] The present invention relates to a sunscreen product, a cosmetic or a pharmaceutical preparation or a household care product, which includes at least one major organic and / or inorganic UV filter, a certain type of mycosporine-like amino acid compound and optionally at least one film-forming agent. These products and preparations provide improved water resistance and thus enhanced SPF performance without generating an unpleasant stickiness. Additionally, the present invention relates to the use of such mycosporine-like amino acid compounds for improving the water resistance and thus the SPF performance of a sunscreen product, a cosmetic or a pharmaceutical preparation or a household care product, which includes at least one major organic and / or inorganic UV filter and optionally at least one film-forming agent. Finally, the present invention relates to a method for enhancing the water resistance and thus the SPF performance of a sunscreen product, a cosmetic or a pharmaceutical preparation or a household care product by adding a certain type of mycosporine-like amino acid compound, which includes at least one major organic and / or inorganic UV filter and optionally at least one film-forming agent. BACKGROUND ART

[0002] The negative effects of exposure to UV rays are well known. Prolonged exposure to sunlight can cause damage such as skin sunburn and make hair dry and brittle. When the skin is exposed to UV rays with wavelengths from 290 nm to 400 nm, long-term damage may lead to serious diseases such as skin cancer, and the type of damage depends on the wavelength of the radiation.

[0003] UV rays can also cause aging by forming free radicals in the skin. Free radicals include, for example, singlet oxygen, hydroxyl, superoxide anion, nitric oxide and hydrogen radicals. Free radicals attack DNA, membrane lipids and proteins, thus generating carbonyl groups. These in turn react with oxygen to produce peroxy radicals, which can attack neighboring fatty acids to produce new carbonyl groups. This cascade leads to a chain reaction that produces lipid peroxidation products. Damage to cell membranes results in a loss of cell permeability, an increase in intercellular ion concentration and a decrease in the ability to excrete or detoxify waste products. The ultimate result is that the skin loses elasticity and wrinkles appear. This process is generally referred to as photoaging.

[0004] In addition, UVA radiation can trigger phototoxic or photoallergic skin reactions.

[0005] UV rays are classified into UVA rays (320 nm to 400 nm) or UVB rays (280 nm to 320 nm) according to their wavelengths.

[0006] To mitigate these negative effects of UV radiation, i.e., to protect the skin and keratinous materials from the effects of UV radiation, sunscreens / sun protection compositions are commonly used, which contain screening agents that are active in the UVA range and the UVB range (i.e., over the entire range from 280 nm to 400 nm).

[0007] UV filters are compounds that have a significant absorption capacity for ultraviolet radiation. They are used, inter alia, in sun protection products, cosmetics, dermatological and pharmacological preparations or sunscreens, and also for improving the lightfastness of industrial products such as paints, varnishes, plastics, textiles, polymers such as polymers and copolymers of monoolefins and diolefins, polystyrene, polyurethanes, polyamides, polyesters, polyureas and polycarbonates, packaging materials and rubbers.

[0008] Organic and inorganic UV filters are classified into UVA filters and UVB filters according to the position of their absorption maxima; if a UV filter absorbs both UVA and UVB, it is called a UVA / B broad-spectrum absorber or a UVA / UVB broad-spectrum filter.

[0009] To obtain the desired maximum level of UV radiation protection, sun protection products or cosmetics, especially dermatological and pharmacological preparations, are formulated to contain mixtures of UV filters with different concentrations, and the choice of UV filters used is determined by regulations within a country or economic region. For example, UV filters that can be used for skin protection are regulated in the United States by the US FDA via its OTC monograph system and in the European Union by the Cosmetics Regulation. There are also regulations regarding the use of UV filters in other countries and regions. These regulations not only specify the filters that can be used but also determine the maximum usage levels of each UV filter. Thus, there are limited UV filters available for achieving high efficacy in terms of both SPF and UVA or UVB protection.

[0010] When formulating updated sunscreen formulations to meet current requirements, formulators must consider improved water resistance as a key parameter, since sunscreens are often used outdoors in close proximity to water bodies. Exposure of a sunscreen product to water (such as typically occurs during bathing) can cause significant removal of the UV filter from the skin by exudation or by physical removal, resulting in a reduced ability to protect against UV rays. This can be indicated by a significant decrease in the SPF of the composition. For modern consumers who seek both comfort and ease of use from their sunscreen products, it is not ideal to reapply the product after every exposure to water. In addition, the protection provided by sunscreens can be affected by sweating; indeed, a decrease in the efficacy of sunscreen products due to sweat has been demonstrated in athletes, and their rates of skin cancer have increased.

[0011] Typically, sufficient or high water resistance can be achieved by preparing a completely anhydrous formulation; generating a w / o emulsion; adding alcohol to dissolve water-insoluble substances that deposit from the insoluble layer onto the skin; obtaining a metastable o / w emulsion with a low content of emulsifier; and entrapping a filter in skin-compatible liposomes or sponges. One or more of these strategies are used when formulating a waterproof formulation.

[0012] The water resistance of a sunscreen product can be further improved by adding a film-forming polymer. Waterproof products are more likely to achieve lower transdermal delivery because their components are contained within the applied film. This factor enables waterproof sunscreens to provide more persistent SPF protection than standard sunscreen products. Additionally, the UV filters entrapped in the film have very low transdermal delivery to the body, thus reducing the risk of chemical penetration through the skin and reducing the accumulation of the substances.

[0013] However, these film-forming polymers are not effective enough and / or make the product unappealing to the end consumer due to the resulting sensory properties, so such products often exhibit a greasy, dull, heavy, or sticky feeling on the skin.

[0014] In addition to maintaining the efficacy of the sunscreen when in contact with water, concerns are also increased regarding the accumulation of trace sunscreen components, which may harm the flora and fauna in lakes, rivers, and the ocean.

[0015] Therefore, there remains a continuing need to provide additional substances for improving the water resistance of sunscreen products, cosmetic or pharmaceutical formulations, or household care products that include a UV filter and optionally a film-forming agent.

[0016] Accordingly, it is an object of the present invention to remedy the drawbacks of the prior art and to provide sunscreen products, cosmetic or pharmaceutical formulations, or household care products that exhibit improved water resistance and thus exhibit high SPF performance and also provide excellent UV protection after bathing. In addition, such products or formulations should exhibit excellent sensory properties, especially without an unpleasant stickiness.

[0017] Another object of the present invention is to provide the use of a substance for improving the water resistance and thus the SPF performance of a sunscreen product, cosmetic or pharmaceutical formulation, or household care product that includes a UV filter and a film-forming agent.

[0018] Yet another object of the present invention is to provide a method for improving the water resistance and thus the SPF performance of a sunscreen product, cosmetic or pharmaceutical formulation, or household care product that includes a UV filter and a film-forming agent.

[0019] Surprisingly, it has been found that the water resistance and thus the SPF performance of sun protection products, cosmetics or pharmaceutical preparations or household care products can be significantly improved by adding a certain type of mycosporine - like amino acid compound without negatively affecting the sensory properties.

[0020] This problem is solved by the subject - matter of the independent claims. However, in the following detailed description according to the wording of the dependent claims, in combination with the appended examples and drawings, further aspects of the invention are also apparent. Summary of the Invention

[0021] To solve the above problems, in a first aspect, the present invention provides a sun protection product, a cosmetic or a pharmaceutical preparation or a household care product, which comprises or consists of the following:

[0022] (a) at least one major organic and / or inorganic UV filter; and

[0023] (b) at least one mycosporine - like amino acid compound,

[0024] The at least one mycosporine - like amino acid compound is represented by the general formula (V)

[0025]

[0026] as defined herein, or its tautomer or stereoisomer or salt;

[0027] Or

[0028] represented by the general formula (VI)

[0029]

[0030] as defined herein, or its tautomer or stereoisomer or salt;

[0031] or any mixture of the above compounds; and

[0032] (c) optionally at least one film - forming agent.

[0033] In a second aspect, the present invention provides the use of at least one mycosporine - like amino acid compound or a mixture thereof as defined herein for improving the water resistance and SPF performance of a sun protection product, a cosmetic or a pharmaceutical preparation or a household care product, which comprises at least one major organic and / or inorganic UV filter and optionally a film - forming agent.

[0034] Finally, the present invention relates, in another aspect, to a method for improving the water resistance and SPF of a sunscreen product, a cosmetic or pharmaceutical preparation, or a household care product, which comprises at least one major organic and / or inorganic UV filter and optionally a film-forming agent, said method comprising adding to said sunscreen product, cosmetic or pharmaceutical preparation, or household care product an effective amount of a mycosporine-like amino acid compound or a mixture thereof as defined herein, said sunscreen product, cosmetic or pharmaceutical preparation, or household care product comprising at least one UV filter and optionally a film-forming agent.

[0035] The invention is defined in the appended claims. However, the invention itself, its preferred variants, other objects and advantages also become apparent from the following detailed description in conjunction with the appended examples. Detailed Description

[0036] In the context of the present invention, the following general meanings apply:

[0037] As used herein, unless the context clearly indicates otherwise, the singular forms "a / an" and "the" include plural referents. Thus, for example, reference to "a cosmetic preparation", "the cosmetic preparation" or "a cosmetic preparation" also includes a plurality of cosmetic preparations.

[0038] The terms "comprising" and "including" are to be understood as open-ended terms and mean that the named components following said terms are necessary, but not "limited to" these named components, and other components may be added and still be encompassed by the present invention.

[0039] As used according to the present invention, the term "consisting of" means that the total amount of components (a) and (b) adds up to up to 100% by weight based on the total weight of the sunscreen product or cosmetic or pharmaceutical preparation, and indicates that the subject is closed and may only include the expressly stated limitations.

[0040] Whenever reference is made to "comprising", it is intended to cover both meanings as alternatives, i.e., unless the context clearly indicates otherwise, the meaning may be "comprising" or "consisting of".

[0041] The term "optionally" means that the subsequently described compound may be present but need not be present in the composition, and the description includes variants that contain the compound or variants in which the compound is absent.

[0042] The term "or" or "and / or" is used as a functional word to indicate that two words or phrases are to be taken together or separately.

[0043] All endpoints of ranges for the same component or property are inclusive and may be combined separately.

[0044] The term "compound" or "compounds of the invention" refers to all compounds covered by the structural formula (V) and / or formula (VI) and / or formula (VII) and / or formula (XIII) and / or formula (IX) and / or formula (X) and / or formula (A) disclosed herein and their sub-formulas, and includes each sub-genus within the formula and all specific compounds whose structures are disclosed herein.

[0045] Compounds can be identified by their chemical structure and / or chemical name. When there is a conflict between the chemical structure and the chemical name, the chemical structure determines the identity of the compound.

[0046] The term "at least one... compound" means that the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention can include any one of the individual compounds described subsequently or a mixture of two, three, four, five, six or even more different said subsequent compounds.

[0047] The term "effective amount of a compound" means an amount of the compound sufficient to achieve the desired effect or improvement. For example: "effective amount of an antimicrobial agent" means the amount or concentration of the antimicrobial agent sufficient to produce an antimicrobial effect.

[0048] The term "cosmetic or pharmaceutical preparation" in the context of the present invention is a composition for cosmetic or pharmaceutical purposes, which compositions contain UV absorbers to protect the skin or hair from the effects of UV radiation. In addition to providing photoprotection, the cosmetic or pharmaceutical preparations according to the invention can also be used to provide anti-aging benefits to the skin, lighten or prevent skin darkening, improve the appearance of the skin, reduce the visible signs of skin aging and improve the glow and firmness of the skin.

[0049] The term "sunscreen composition" or "sunscreen agent" or "skin care product" (also referred to as "sun oil", "sunscreen" or "sun wash") refers to any topical product that reflects and / or absorbs certain portions of UV radiation, thereby helping to prevent sunburn and, most importantly, prevent skin cancer. Thus, the term "sunscreen composition" should be understood to include not only sunscreen compositions but also any cosmetic composition that provides UV protection. According to the present invention, the sunscreen composition can contain one or more active agents (e.g., organic UV filters) as well as other ingredients or additives (e.g., emulsifiers, emollients, viscosity regulators, stabilizers, preservatives or fragrances). Sunscreen agents are available as washes, sprays, gels, foams (such as expanding foam washes or whipped lotions), sticks, powders and other topical products. UV-absorbing compounds are used not only in sunscreen agents but also in other personal care products such as lipsticks, shampoos, hairsprays, body washes, hand soaps and insect repellents.

[0050] In the context of the present invention, the term "household care product" is a necessity for daily household care and cleaning. They are used to maintain hygiene and a good household atmosphere. Household care products typically include laundry detergents (powders, liquids, and tablets), fabric conditioners, dishwashing detergents (liquids and tablets), hard floor and surface cleaners, glass cleaners, carpet cleaners, oven cleaners, air fresheners, disinfectants, stain removers, car wash products. These products are typically manufactured in the form of liquids, powders, sprays, granules, etc. Formulations containing sunscreen agents prevent premature photo damage and photo bleaching of surfaces and the household care formulations themselves.

[0051] As used herein, the term "light stabilizer" is a compound suitable for protecting body care agents and household cleaners and treatments from the effects of photolytic degradation.

[0052] The term "photo stability" refers to the ability of a UV filter or any other molecule exposed to sunlight to remain stable under radiation. In particular, this means that the compound does not undergo a degradation process under UV radiation.

[0053] As used herein, the term "sun protection factor (SPF)" indicates the degree of protection of a sunscreen composition against the skin. In particular, this factor indicates how much longer protected skin can be exposed to sunlight without sunburn compared to untreated skin. For example, if a sunscreen composition with an SPF of 15 is evenly applied to the skin of a person who would normally get sunburned after 10 minutes of sun exposure, the sunscreen allows the person skilled in the art to stay in the sun 15 times longer. In other words, SPF 15 means that 1 / 15 of the burning UV radiation will reach the skin, assuming the sunscreen is evenly applied in a thick dose of 2 milligrams per square centimeter (mg / cm 2 ).

[0054] The term "critical wavelength" is defined as the wavelength at which the area under the UV protection curve (protection % vs. wavelength) is 90% of the total area under the curve in the UV region (280 nm - 400 nm). For example, a critical wavelength of 370 nm indicates that the protection of the sunscreen composition is not limited to the wavelengths of UV-B (i.e., wavelengths from 280 nm to 320 nm), but extends to 370 nm such that 90% of the total area under the protection curve in the UV region is reached at 370 nm. The higher the critical wavelength, the better the protection against UV radiation.

[0055] According to the present invention, the main object of the present invention is solved by a sunscreen product, a cosmetic, in particular a dermatological or pharmaceutical preparation or a household care product, which sunscreen product, cosmetic, in particular a dermatological or pharmaceutical preparation or a household care product comprises or consists of the following:

[0056] (a) at least one main organic and / or inorganic UV filter;

[0057] (b) at least one mycosporine - like amino acid compound,

[0058] The at least one mycosporine - like amino acid compound is represented by the general formula (V)

[0059]

[0060] wherein

[0061] -Z is selected from the group consisting of O-R2' or amide';

[0062] -R1' is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted C(alkyl)2, unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), CR7'R8', C=O, halogen, O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl) and unsubstituted or substituted N(heteroaryl) and unsubstituted or substituted C - spiro ring;

[0063] -R2' is selected from the group consisting of: H, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl;

[0064] -Amide' is selected from the group consisting of: NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), and unsubstituted or substituted NR9'R10', unsubstituted or substituted -N(O-alkyl)(alkyl)(Weinreb amide), -N(OH)(H)(hydroxamic acid), and unsubstituted or substituted -N(OH)(alkyl)(alkylated hydroxamic acid);

[0065] -R3' is selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9'R10', and unsubstituted or substituted C-spiro;

[0066] - The substituents R4', R5' and R6', which can be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, -S(=O)2OH, sulfonyl, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl) and unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9'R10' and unsubstituted or substituted C-spiro ring;

[0067] - The R7' and R8', which can be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl) and unsubstituted or substituted NR9'R10';

[0068] -R9' and R10', which can be the same or different, are each independently selected from the group consisting of: H, OH, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, and unsubstituted or substituted heteroaryl;

[0069] -Y is selected from the group consisting of H and unsubstituted or substituted alkyl; and

[0070] -R is unsubstituted alkyl or substituted alkyl;

[0071] or a tautomer or stereoisomer or salt of the above compound;

[0072] or represented by the general formula (VI)

[0073]

[0074]

[0075] wherein

[0076] -R1” is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted C(alkyl)2, unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), -CR7”R8”, C=O, halogen, O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl), unsubstituted or substituted N(heteroaryl), and unsubstituted or substituted C-spiro;

[0077] -R2” is selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH-C(=O)-O-Y, -C(=O)-amide”, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9”R10” and unsubstituted or substituted C-spiro;

[0078] -X is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted CH(alkenyl), unsubstituted or substituted CH(alkynyl), unsubstituted or substituted CH(alkoxy), unsubstituted or substituted CH(alkylthio), unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), -CR7”R8”, C=O, O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl), unsubstituted or substituted N(heteroaryl) and unsubstituted or substituted C-spiro;

[0079] - The substituents R4”, R5” and R6”, which can be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, -S(=O)2OH, sulfonyl, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl) and unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9”R10”, and unsubstituted or substituted C-spiro ring;

[0080] - R7” and R8”, which can be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl) and unsubstituted or substituted NR9”R10”;

[0081] -amide” is selected from the group consisting of: NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9”R10”, unsubstituted or substituted -N(O-alkyl)(alkyl)(Weinreb amide), -N(OH)(H)(isohydroxamic acid), and unsubstituted or substituted -N(OH)(alkyl)(alkylated isohydroxamic acid);

[0082] - R9” and R10”, which may be the same or different, are each independently selected from the group consisting of: H, OH, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, and unsubstituted or substituted heteroaryl;

[0083] - Y is selected from the group consisting of H and unsubstituted or substituted alkyl; and

[0084] - R is unsubstituted alkyl or substituted alkyl;

[0085] or a tautomer or stereoisomer or salt of the above compound;

[0086] or any mixture of the above compounds; and

[0087] (c) optionally at least one film-forming agent.

[0088] The component (a) of a sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the first aspect of the present invention relates to at least one major organic and / or inorganic UV filter.

[0089] In the art, it is well-known that UV filters are used to block radiation. A UV filter is a compound or a mixture of compounds that blocks or absorbs ultraviolet (UV) rays. UV classification includes UVA (320 nm to 400 nm), UVB (290 nm to 320 nm), and UVC (200 nm to 280 nm). UV-absorbing compounds are used not only in sunscreens but also in other personal care products such as lipsticks, shampoos, hairsprays, body washes, hand soaps, and insect repellents. Chemical filters prevent UV radiation by absorption, reflection, or scattering. Reflection and scattering are achieved by inorganic physical UV filters such as titanium dioxide (TiO2) and zinc oxide (ZnO). Absorption (mainly of UVB) is accomplished by organic UV filters, which are called chemical UV filters.

[0090] The sunscreen product, cosmetic or pharmaceutical preparation, or household care product according to the invention advantageously comprises at least one UVA filter and / or at least one additional UVB filter and / or a broadband filter and / or at least one inorganic pigment, preferably at least one UVA filter and at least one UVB filter, for blocking UV radiation.

[0091] For example, at least one primary UV filter can be one or more organic UV filters and / or one or more inorganic UV filters. Non-limiting examples of UV filters include:

[0092] (i) Sparingly soluble UV filters (not significantly soluble in water or oil), such as methylene bis-benzotriazolyl tetramethylbutylphenol, triphenyltriazine, benzophenone, 1,1'-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl-]phenyl];

[0093] (ii) Oil-soluble organic UV filters (at least partially soluble in oil or organic solvents), such as bis-ethylhexyloxyphenol methoxyphenyltriazine, butyl methoxydibenzoylmethane (BMBM), oxybenzone, sulisobenzone, diethylhexylbutamidotriazone (DBT), methylene bis-benzotriazolyl tetramethylbutylphenol, homosalate, isopentyl p-methoxycinnamate, 4-methylbenzylidene camphor, octocrylene (OCR), polysiloxane-15, and diethylamino hydroxybenzoyl hexyl benzoate (DHHB);

[0094] (iii) Inorganic UV filters, such as titanium oxide and zinc oxide, iron oxide, zirconium oxide, and cerium oxide; and

[0095] (iv) Water-soluble UV filters such as phenylbenzimidazole sulfonic acid (PBSA), sulisobenzone-sodium salt, benzylidene camphor sulfonic acid, camphor benzalkonium methyl sulfate, cinoxate, phenyl dibenzimidazole tetrasulfonate disodium, terephthalylidene dicamphor sulfonic acid, PABA, and PEG-25 PAB; and any mixtures thereof.

[0096] Many different organic compounds can be used as UV filters. They are divided into several structural classes:

[0097] (1) Benzophenones

[0098] a. Benzophenone-3 (BP3)

[0099] b. Benzophenone-4 (BP4)

[0100] (2) Salicylates

[0101] a. Homosalate (HMS)

[0102] b. 2-Ethylhexyl salicylate (EHS)

[0103] (3) p-Aminobenzoic acid and derivatives

[0104] a. Diethylhexyl PABA (OD-PABA)

[0105] b. 4-p-Aminobenzoic acid (PABA)

[0106] (4) Benzimidazole derivatives

[0107] a. Phenylbenzimidazole sulfonic acid (PMDSA)

[0108] b. Phenyl dibenzimidazole tetrasulfonate disodium (bis-dibenzoylmethane disodium)

[0109] (5) Triazines

[0110] a. Ethylhexyl triazone (OT)

[0111] b. Diethylhexyl butamido triazone (DBT)

[0112] c. Bis-ethylhexyloxyphenol methoxyphenyl triazine (EMT)

[0113] (6) Benzotriazoles

[0114] a. Drometrizole trisiloxane (DRT)

[0115] b. Methylene bis-benzotriazolyl tetramethylbutylphenol (MBP, biscotrizole)

[0116] (7) Dibenzoylmethane derivatives

[0117] a. 4-tert-butyl-4'-methoxydibenzoylmethane (BM-DBM, avobenzone)

[0118] (8) Cinnamate

[0119] a. Ethylhexyl methoxycinnamate (OMC)

[0120] b. Isoamyl p-methoxycinnamate (IMC, amisulbrom)

[0121] (9) Camphor derivative

[0122] a. Phenylbenzimidazole sulfonic acid (PDSA)

[0123] b. 3-Methylbenzylidene camphor (3BC)

[0124] c. Benzylidene camphor sulfonic acid (BCSA)

[0125] d. 4-Methylbenzylidene camphor (4-MBC)

[0126] e. Polyacrylamidomethyl benzylidene camphor (PBC)

[0127] (10) Camphor benzalkonium methyl sulfate (CBM)

[0128] According to the present invention, at least one inorganic UV filter (a) is selected from the group of pigments consisting of titanium dioxide (TiO2) (amorphous or crystalline, rutile and / or anatase form), zinc oxide (ZnO), iron oxide (Fe2O3), zirconium oxide (ZrO2), silicon dioxide (SiO2), manganese oxide (e.g., MnO), aluminum oxide (Al2O3), cerium oxide (Ce2O3), barium carbonate (BaCO3), calcium carbonate (CaCO3), and mixtures thereof.

[0129] Preferably, at least one inorganic UV filter is titanium dioxide, zinc oxide, and mixtures thereof. More preferably, at least one inorganic UV filter is titanium dioxide and / or zinc oxide, and most preferably, at least one inorganic UV filter is zinc oxide. ZnO has a broad UVA / UVB absorption curve, while TiO2 provides better UVB protection.

[0130] According to another variant, at least one inorganic UV filter is in particulate form, with a weight average particle size d 50 from 1 nm to 1000 nm, preferably from 3 nm to 800 nm, more preferably from 5 nm to 600 nm, and most preferably from 10 nm to 400 nm.

[0131] Inorganic UV filters also cover nano-pigments of untreated or treated metal oxides (average size of the main particles: generally 1 nm to 100 nm, preferably 3 nm to 90 nm, more preferably 5 nm to 80 nm and most preferably 10 nm to 70 nm), such as, for example, nano-pigments of titanium dioxide (TiO2) (amorphous or crystalline, rutile and / or anatase form), zinc oxide (ZnO), iron oxide (Fe2O3), zirconium dioxide (ZrO2), silicon dioxide (SiO2), manganese oxide (e.g., MnO), aluminum oxide (Al2O3), cerium oxide (Ce2O3), barium carbonate (BaCO3), calcium carbonate (CaCO3) or mixtures thereof.

[0132] The treated nano-pigments and non-nano-pigments are pigments that have been subjected to one or more surface treatments of chemical, electronic, mechanochemical and / or mechanical properties using compounds such as the following: amino acids, beeswax, fatty acids, fatty acid esters, fatty alcohols, anionic surfactants, lecithin, sodium, potassium, zinc, iron or aluminum salts of fatty acids, metal (titanium or aluminum) alkoxides, polyethylene, silicone, proteins (collagen or elastin), alkanolamines, silica, metal oxides, sodium hexametaphosphate, aluminum oxide or glycerol, hydrated silica, stearic acid, jojoba esters or glutamate derivatives,

[0133] The treated nano-pigments and non-nano-pigments may more particularly be titanium dioxide treated with the following: silica and alumina, alumina and aluminum stearate, alumina and aluminum laurate, aluminum hydroxide, iron oxide and iron stearate, silica, alumina and silicone, sodium hexametaphosphate, octyltrimethoxysilane, alumina and stearic acid, alumina and glycerol, or alumina and silicone or polyhydroxystearic acid, hydrated silica, jojoba esters, stearoyl glutamate, glutamate and derivatives, trimethoxyoctanoyl silane, glycerol, dimethylpolysiloxane hydrogen dimethylsiloxane, dimethyl silicone oil or combinations thereof. Other titanium dioxide nano-pigments treated with silicone are preferably TiO2 treated with octyltrimethylsilane, preferably having an average size of the primary particles of 25 nm to 40 nm; TiO2 treated with polydimethylsiloxane, preferably having an average size of the primary particles of 21 nm; or TiO2 treated with polydimethylhydrogensiloxane, preferably having an average size of the primary particles of 25 nm.

[0134] Coated zinc oxide nano-pigments and zinc oxide non-nano-pigments are, for example, ZnO coated with polymethylhydrosiloxane; a dispersion of ZnO in cyclopolysiloxane / oxyethylated polydimethylsiloxane, comprising 30% or 80% of nano or non-nano zinc oxide coated with silica and polymethylhydrosiloxane; ZnO coated with perfluoroalkyl phosphate and a copolymer based on perfluoroalkylethyl as a dispersion in cyclopentasiloxane; ZnO coated with a cross-linked polymer of dimethoxydiphenylsilane triethoxyoctylsilane; ZnO coated with glutamic acid; ZnO coated with octyltriethoxysilane; ZnO coated with dimethylpolysiloxane; ZnO coated with a silicone-grafted acrylic polymer dispersed in cyclodimethylsiloxane; ZnO coated with triethoxyoctylsilane; ZnO coated with polyhydroxystearic acid; alumina-treated ZnO dispersed in a mixture of ethylhexyl methoxycinnamate / PVP-hexadecene / polymethylsiloxane copolymer; ZnO coated with silica and polymethylsilsesquioxane; ZnO dispersed in a polyhydroxystearic acid condensate; or ZnO coated with a mixture of: stearoylglutamic acid, jojoba esters, polyhydroxystearic acid, isopropyl titanate triisostearate, hydrogenated olive oil stearate, cetearyl nonanoate, white wax, dimethylpolysiloxane, a cross-linked polymer of dimethoxydiphenylsilane triethoxyoctylsilane, octyltriethoxysilane, glutamic acid and sodium stearoyl lactate.

[0135] Also preferred are optionally hydrophobized particulate UV filters or inorganic pigments such as oxides of iron (Fe2O3), zirconium (ZrO2), silicon (SiO2), manganese (e.g. MnO), aluminium (Al2O3), cerium (e.g. Ce2O3), barium carbonate (BaCO3), calcium carbonate (CaCO3) or mixtures thereof.

[0136] The at least one major organic and / or inorganic UV filter is preferably selected from the group consisting of: camphor benzalkonium methyl sulfate, homosalate, benzophenone-3, phenylbenzimidazole sulfonic acid, terephthalylidene dicamphor sulfonic acid, butyl methoxydibenzoylmethane, benzylidene camphor sulfonic acid, octocrylene, polyacrylamidomethyl benzylidene camphor, ethylhexyl methoxycinnamate, PEG-25 PABA, isoamyl p-methoxycinnamate, ethylhexyl triazone, cresyl triazone, diethylhexyl butamido triazone, 4-methylbenzylidene camphor, ethylhexyl salicylate, diethylhexyl PABA, benzophenone-4, benzophenone-5, methylene bis-benzotriazolyl tetramethylbutylphenol (nanoscale), phenyl dibenzimidazole tetrasulfonate disodium, bis-ethylhexyloxyphenol methoxyphenyl triazine, polysiloxane-15, titanium dioxide, titanium dioxide (nanoscale), diethylamino hydroxybenzoyl benzoic acid hexyl ester, terphenyl triazine (nanoscale), zinc oxide, zinc oxide (nanoscale), phenylenebis-diphenyltriazine, methoxypropylamino cyclohexenyl ethoxyethyl cyanoacetate, bis-(diethylamino hydroxybenzoyl benzoyl) piperazine, TEA-salicylate, benzophenone-8, PABA, diethylhexyl PABA, menthyl anthranilate and any mixtures thereof.

[0137] More preferably, the at least one major organic and / or inorganic UV filter is selected from the group consisting of: camphor benzalkonium methyl sulfate, benzophenone-3, terephthalylidene dicamphor sulfonic acid, benzylidene camphor sulfonic acid, polyacrylamidomethyl benzylidene camphor, PEG-25 PABA, cresyl triazone, diethylhexyl PABA, benzophenone-4, benzophenone-5, methylene bis-benzotriazolyl tetramethylbutylphenol, polysiloxane-15, titanium dioxide (nanoscale), terphenyl triazine (nanoscale), phenylenebis-diphenyltriazine, methoxypropylamino cyclohexenyl ethoxyethyl cyanoacetate, bis-(diethylamino hydroxybenzoyl benzoyl) piperazine, benzophenone-8, diethylhexyl PABA, homosalate, phenylbenzimidazole sulfonic acid, butyl methoxydibenzoylmethane, octocrylene, ethylhexyl methoxycinnamate, isoamyl p-methoxycinnamate, ethylhexyl triazone, diethylhexyl butamido triazone, 4-methylbenzylidene camphor, ethylhexyl salicylate, diethylamino hydroxybenzoyl benzoic acid hexyl ester, bis-ethylhexyloxy phenol methoxyphenyl triazine, diethylamino hydroxybenzoyl benzoic acid hexyl ester, zinc oxide, zinc oxide (nanoscale), menthyl anthranilate and any mixtures thereof.

[0138] Most preferably, the at least one major organic and / or inorganic UV filter is selected from the group consisting of: homosalate, phenylbenzimidazole sulfonic acid, butyl methoxydibenzoylmethane, octocrylene, ethylhexyl methoxycinnamate, isoamyl p-methoxycinnamate, ethylhexyl triazone, diethylhexyl butamido triazone, 4-methylbenzylidene camphor, ethylhexyl salicylate, diethylamino hydroxybenzoyl hexyl benzoate, bis-ethylhexyloxyphenol methoxyphenyl triazine, titanium dioxide, diethylamino hydroxybenzoyl hexyl benzoate, zinc oxide, zinc oxide (nanoscale), menthyl anthranilate, and any mixtures thereof.

[0139] The previously cited UV filters that can be used in the context of the present invention are preferred, but of course not limiting.

[0140] The aforementioned major organic and / or inorganic UV filters are used as a single component or preferably in combination with two, three, four or more of the UV filters as specified above in a sunscreen, cosmetic or pharmaceutical preparation or a household care product.

[0141] In order to optimize the SPF, i.e., to obtain a high SPF in the range of 6 to 100, preferably in the range of 6 to 70, and to cover a broad UVA and UVB range, the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the present invention comprises at least two, more preferably at least three, most preferably at least four or even more different major organic and / or inorganic UV filters, i.e., in particular organic UV filters and / or inorganic pigments (UV filtering pigments). Such a composition according to the present invention is particularly suitable for protecting the skin and hair.

[0142] Advantageously, the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the present invention comprises at least one UVA filter and at least one UVB filter. Such a sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the present invention provides a broader range of light protection, i.e., protection against both UVA and UVB.

[0143] The combination of different classes of effective sunscreen UV filters such as UVA filters, UVB, broadband filters, inorganic pigments, etc. provides reliable protection against different UV rays in the wavelength range of 290 nm to 400 nm.

[0144] In another preferred variant, the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention comprises a combination with one, two, three or more broadband filters selected from the group consisting of: 2-ethylhexyl-2-cyano-3,3-diphenylacrylate, ethyl-2-cyano-3,3'-diphenylacrylate, dihydroxy-4-methoxybenzophenone, 2,4-dihydroxybenzophenone, tetrahydroxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2-hydroxy-4-n-octyloxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, sodium hydroxymethoxybenzophenone sulfonate, disodium-2,2'-dihydroxy-4,4'-dimethoxy-5,5'-disulfonylbenzophenone, phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3(1,3,3,3-tetramethyl-1-(trimethylsilyloxy)disiloxanyl)propyl), 2,2'-methylene-bis-(6-(2H-benzotriazol-2-yl)-4-1,1,3,3-tetramethylbutyl)phenol) (methylene-bis-benzotriazolyltetramethylbutylphenol), 2,4-bis-[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-1,3,5-triazine, 2,4-bis-[{(4-(2-ethylhexyloxy)-2-hydroxy}phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: anisotriazine), 2,4-bis-[{(4-(3-sulfonato)-2-hydroxypropoxy)-2-hydroxy}phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine sodium salt, 2,4-bis-[{(3-(2-propoxy)-2-hydroxypropoxy)-2-hydroxy}phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, 2,4-bis-[{4-(2-ethylhexyloxy)-2-hydroxy}phenyl]-6-[4-(2-methoxyethylcarbonyl)phenylamino]-1,3,5-triazine, 2,4-bis-[{4-(3-(2-propoxy)-2-hydroxypropoxy)-2-hydroxy}phenyl]-6-[4-(2-ethylcarboxy)phenylamino]-1,3,5-triazine, 2,4-bis-[{4-(2-ethylhexyloxy)-2-hydroxy}phenyl]-6-(1-methylpyrrol-2-yl)-1,3,5-triazine, 2,4-bis-[{4-tris-(trimethylsilyloxy)silyloxy)-2-hydroxy}phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, 2,4-bis-[{4-(2”-methylacryloxy)-2-hydroxy}phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, 2,4-bis-[{4-(1',1',1',3',5',5',5'-heptamethylsilyloxy-2”-methylpropoxy)-2-hydroxy}phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, dioctyl butylamide triazone (INCI: Dioctyl Butylamide Triazone), 2,4-bis-[5-1(dimethylpropyl)benzoxazol-2-yl-(4-phenyl)-imino]-6-(2-ethylhexyl)-imino-1,3,5-triazine, 4,4',4''-(1,3,5-triazine-2,4,6-triamino)tri-benzoic acid tris(2-ethyl-hexyl ester) (also known as: 2,4,6-tris[anilino(p-carbon-2'-ethyl-1'-hexyloxy)]-1,3,5-triazine (INCI: Octyl Triazone), 2,4,6-triphenylphenyl-4-yl-1,3,5-triazine, 2-ethylhexyl 4-methoxycinnamate (Ethylhexyl Methoxycinnamate), benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester (Homosalate), 2-ethylhexyl salicylate (Ethylhexyl Salicylate), 2-ethylhexyl 4-(dimethylamino)benzoate (Dimethyl PABA Ethylhexyl Ester), N,N,N-trimethyl-4-(2-oxobor-3-ylmethylene), anilinium methyl sulfate (Camphor Benzalkonium Methyl Sulfate), dimethyl dimethyl diethyl benzylmalonate (Polysilicone-15) and any mixtures thereof.,

[0145] The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention comprises a major sunscreen factor, namely an inorganic and / or organic UV filter, the total amount of which is such that the product or preparation according to the invention has a sun protection factor SPF of from 6 to 100, preferably from 6 to 70. Such a composition according to the invention is particularly suitable for protecting the skin, hair and nails.

[0146] Component (b) in the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the first aspect of the invention is at least one mycosporine-like amino acid compound, the at least one mycosporine-like amino acid compound being represented by the general formula (V)

[0147]

[0148] as defined herein;

[0149] or

[0150] represented by the general formula (VI)

[0151]

[0152] as defined herein.

[0153] Mycosporine-like amino acids (MAAs) are small secondary metabolites produced by organisms living in environments with high sunlight exposure, typically marine environments. MAAs are imine derivatives of mycosporines and contain an amino-cyclohexene-imine ring linked to an amino acid, amino alcohol, or amino group. The compounds enable electron delocalization. Additionally, the compounds demonstrate antioxidant qualities.

[0154] Unless otherwise stated, in the context of the present invention, particularly for the definition of mycosporine-like amino acid compounds represented by any of the general formulas, the following general meanings apply:

[0155] According to the present invention, the term "halogen" residue / portion or group, alone or as part of another substituent, refers to F, Cl, Br, or I.

[0156] According to the present invention, the term "alkyl", alone or as part of another substituent, refers to a saturated or mono-unsaturated or poly-unsaturated straight-chain or branched-chain monovalent hydrocarbon group obtained by removing a hydrogen atom from a single carbon atom of the corresponding parent alkane.

[0157] In a preferred variant, the term "alkyl" also includes any alkyl portion in a group derived therefrom, such as an alkoxy, alkylthio, alkylsulfonyl saturated straight-chain or branched-chain hydrocarbon group having 1 to 10, 1 to 8, 1 to 6, or 1 to 4 carbon atoms.

[0158] If the alkyl is further bonded to another atom, the group becomes an alkylene or alkylene group. In other words, the term "alkylene" also refers to a divalent straight-chain or branched-chain alkyl group. For example, -CH2CH3 is ethyl, while -CH2CH2- is ethylene.

[0159] The term "alkylene", alone or as part of another substituent, refers to a saturated straight-chain or branched-chain divalent hydrocarbon group obtained by removing two hydrogen atoms from a single carbon atom or two different carbon atoms of the starting alkane.

[0160] In a preferred variant according to the present invention, the straight-chain or branched-chain alkyl group or alkylene group includes 1 to 10 carbon atoms. In still more preferred variants, the straight-chain or branched-chain alkyl group or alkylene group includes 1 to 6 carbon atoms.

[0161] According to the present invention, more preferably, a saturated straight-chain or branched-chain C1 to C6 alkyl group or a saturated straight-chain or branched-chain C1 to C6 alkylene group.

[0162] Most preferably, a straight-chain or branched-chain alkyl group or alkylene group having 1 to 4 carbon atoms.

[0163] Preferred alkyl / partial or alkyl groups include, but are not limited to: C1 to C6 alkyl groups, including methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethyl-1-methylpropyl, and 1-ethyl-2-methylpropyl.

[0164] In a preferred variant, the alkyl / part is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl, and more preferably from the group consisting of methyl and ethyl.

[0165] The alkyl group or alkylene group as defined above may be further substituted.

[0166] The term "alkyl" or "alkylene" also includes groups having any degree of saturation, i.e., groups having only carbon-carbon single bonds ("alkyl" or "alkylene"), groups having one or more carbon-carbon double bonds ("alkenyl"), groups having one or more carbon-carbon triple bonds ("alkynyl"), and groups having a mixture of carbon-carbon single bonds, double bonds, and / or triple bonds.

[0167] According to the present invention, the term "alkenyl", alone or as part of another substituent, refers to an unsaturated straight-chain or branched-chain monovalent hydrocarbon group having at least one carbon-carbon double bond (C=C double bond). The group may be in a cis or trans configuration with respect to the double bond. Such that the term "alkenyl" also includes the corresponding cis / trans isomers.

[0168] In a preferred variant according to the present invention, the straight-chain or branched-chain alkenyl group includes 2 to 10 carbon atoms. In other preferred variants, the straight-chain or branched-chain alkenyl group includes 2 to 6 carbon atoms.

[0169] In still another preferred variant, the straight-chain or branched-chain alkenyl group includes 2 to 4 carbon atoms.

[0170] According to the present invention, preferred are monounsaturated or diunsaturated straight-chain or branched-chain C1 to C6 alkenyl groups.

[0171] Typical alkenyl or alkenyl groups include, but are not limited to: vinyl; propenyl, such as prop-1-en-1-yl, prop-1-en-2-yl, prop-2-en-1-yl (allyl), prop-2-en-2-yl, cycloprop-1-en-1-yl, cycloprop-2-en-1-yl; butenyl, such as but-1-en-1-yl, but-1-en-2-yl, 2-methyl-prop-1-en-1-yl, but-2-en-1-yl, but-2-en-2-yl, but-1,3-dien-1-yl, but-1,3-dien-2-yl, etc.

[0172] The alkenyl groups as defined above may be further substituted.

[0173] According to the present invention, the term "alkynyl", alone or as part of another substituent, refers to an unsaturated straight-chain or branched-chain monovalent hydrocarbon group having at least one carbon-carbon triple bond (C≡C triple bond).

[0174] In a preferred variant according to the present invention, the straight-chain or branched-chain alkynyl group includes from 2 to 10 carbon atoms. In other preferred variants, the alkynyl group has from 2 to 6 carbon atoms. In still other preferred variants, the alkynyl group includes from 2 to 4 carbon atoms.

[0175] According to the present invention, most preferably, it is a monounsaturated or diunsaturated straight-chain or branched-chain C1 to C6 alkynyl group.

[0176] Typical alkynyl / part or alkynyl groups include, but are not limited to: ethynyl; propynyl, such as prop-1-yn-1-yl, prop-2-yn-1-yl, etc.; butynyl, such as but-1-yn-1-yl, but-1-yn-3-yl, but-3-yn-1-yl, etc.

[0177] The alkynyl groups as defined above may be further substituted. The alkyl groups or alkylene groups as defined above may be further substituted.

[0178] According to the present invention, the term "alkoxy", alone or as part of another substituent, refers to a straight-chain or branched-chain group of the formula -O-R, where R is an alkyl group or a net-substituted alkyl group as defined herein.

[0179] In a preferred variant according to the present invention, the straight-chain or branched-chain alkoxy group includes from 2 to 10 carbon atoms. In other preferred variants, the straight-chain or branched-chain alkoxy group includes from 2 to 6 carbon atoms. In still other preferred variants, the straight-chain or branched-chain alkoxy group includes from 2 to 4 carbon atoms.

[0180] According to the present invention, most preferably, it is a straight-chain or branched-chain C1 to C6 alkoxy group.

[0181] Typical alkoxy / partial or alkoxy groups include C1 to C6 alkoxy groups, including C1 to C4 alkoxy groups, such as methoxy, ethoxy, n-propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy, or 1,1-dimethylethoxy; and pentyloxy, 1-methylbutoxy, 2-methylbutoxy, 3-methylbutoxy, 1,1-dimethylpropoxy, 1,2-dimethylpropoxy, 2,2-dimethylpropoxy, 1-ethylpropoxy, hexyloxy, 1-methylpentyloxy, 2-methylpentyloxy, 3-methylpentyloxy, 4-methylpentyloxy, 1,1-dimethylbutoxy, 1,2-dimethylbutoxy, 1,3-dimethylbutoxy, 2,2-dimethylbutoxy, 2,3-dimethylbutoxy, 3,3-dimethylbutoxy, 1-ethylbutoxy, 2-ethylbutoxy, 1,1,2-trimethylpropoxy, 1,2,2-trimethylpropoxy, 1-ethyl-1-methylpropoxy, or 1-ethyl-2-methylpropoxy.

[0182] In a preferred variant, the alkoxy or alkoxy group is selected from the group consisting of methoxy (-O-methyl), ethoxy (-O-ethyl), propoxy (-O-propyl), and butoxy (-O-butyl), more preferably from the group consisting of methoxy (-O-methyl) and ethoxy (-O-ethyl).

[0183] The alkoxy group or alkylene group as defined above may be further substituted.

[0184] According to the present invention, the term "alkylthio" or "thioalkoxy", alone or as part of another substituent, refers to a group of the formula -S-R, where R is an alkyl or substituted alkyl as defined herein.

[0185] According to the present invention, the term "alkyl" or "alkylene" also includes heteroalkyl or heteroalkyl groups. The term "heteroalkyl", alone or as part of other substituents, refers to an alkyl group in which one or more of the carbon atoms are independently replaced by the same heteroatom or another heteroatom or by the same heteroatom group or another heteroatom group. Typical heteroatoms or heteroatom groups that can replace carbon atoms include, but are not limited to, -O-, -S-, -N-, -Si-, -NH-, -S(O)-, -S(O)2-, -S(O)NH-, -S(O)2NH-, etc. and combinations thereof. The heteroatom or heteroatom group can be located at any internal position of the alkyl group.

[0186] Typical heteroatom groups that may be included in these groups include, but are not limited to, -O-, -S-, -O-O-, -S-S-, -O-S-, -NRR-, =NN=, -N=N-, -N=N-NRR, -PR-, -P(O)2-, -POR-, -O-P(O)2-, -SO-, -SO2-, -SR2OR-, etc., where R is independently hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl, substituted cycloheteroalkyl, heteroalkyl, substituted heteroalkyl, heteroaryl, substituted heteroaryl, heteroarylalkyl or substituted heteroarylalkyl, as defined herein.

[0187] The alkyl group or alkylene group as defined above may be further substituted.

[0188] According to the present invention, the term "acyl" or "alkanoyl" alone or as part of another substituent refers to the group R-C(=O)-, where R is hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, arylalkyl, unsubstituted or substituted arylalkyl, unsubstituted or substituted heteroalkyl, unsubstituted or substituted heteroarylalkyl, as defined herein.

[0189] Representative examples include, but are not limited to, formyl, acetyl, propionyl, butyryl, valeryl, benzoyl, cyclohexylcarbonyl, cyclohexylmethylcarbonyl, benzylcarbonyl, etc.

[0190] According to the present invention, the term "cycloalkyl" alone or as part of another substituent refers to a saturated or monounsaturated or polyunsaturated, non-aromatic cyclic monovalent hydrocarbon group, where the carbon atoms are ring-linked and there are no heteroatoms.

[0191] The carbocycle may occur as a monocyclic compound with only a single ring, or as a polycyclic compound with two or more rings.

[0192] In a preferred variant, the term "cycloalkyl" includes a three- to ten-membered monocyclic cycloalkyl or cycloalkyl group or a nine- to twelve-membered polycyclic cycloalkyl or cycloalkyl group. In still more preferred variants, the cycloalkyl moiety includes a five-, six- or seven-membered monocyclic cycloalkyl moiety or a nine- to twelve-membered bicyclic cycloalkyl moiety.

[0193] In a preferred embodiment according to the present invention, the cycloalkyl or group contains 3 to 20 carbon atoms. In an even more preferred embodiment, the cycloalkyl includes 6 to 15 carbon atoms. In the most preferred embodiment, the cycloalkyl includes 6 to 10 carbon atoms. Most preferably, it is a monocyclic C3 to C7 cycloalkyl group.

[0194] Typical cycloalkyl or cycloalkyl groups include, but are not limited to, saturated carbocyclic groups having 3 to 20 carbon atoms, such as C3 to C12 carbocyclic groups, including cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclooctyl, cyclononyl, cyclodecyl, cycloundecyl, and cyclododecyl; cyclopentyl, cyclohexyl, cycloheptyl, and cyclopropyl-methyl, cyclopropyl-ethyl, cyclobutyl-methyl, cyclobutyl-ethyl, cyclopentyl-methyl, cyclopentyl-ethyl, cyclohexyl-methyl or C3- to C7-carbocyclic groups, including cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclopropyl-methyl, cyclopropyl-ethyl, cyclobutyl-methyl, cyclopentyl-ethyl, cyclohexyl-methyl, cyclobut-1-en-1-yl, cyclobut-1-en-3-yl, 3-diene-1-yl, etc.

[0195] Preferred polycyclic cycloalkyl or cycloalkyl groups according to the present invention include, but are not limited to, naphthyl, indenyl groups, etc.

[0196] According to the present invention, the term "cycloalkyl" also includes cycloalkenyl, i.e., an unsaturated cyclic hydrocarbon group containing a C═C double bond between two carbon atoms of the ring molecule. In a broader sense, cycloalkenyl is a compound having one, two or more double bonds, and the number of possible, mostly conjugated double bonds in the molecule depends on the ring size.

[0197] Typical cycloalkenyls include, but are not limited to, cyclopropenyl, cyclopentenyl, cyclohexenyl, cyclopentadienyl, etc.

[0198] According to the present invention, the term "cycloalkyl" also includes cycloalkynyl, i.e., an unsaturated -C≡C- triple bond, containing a cyclic hydrocarbon group between two carbon atoms of the ring molecule, and due to ring strain, the triple bond depends on the ring size.

[0199] Typical cycloalkynyls include cyclomycin.

[0200] The cycloalkyl, cycloalkenyl or cycloalkynyl moieties or groups as defined above may be further substituted.

[0201] According to the present invention, the term "aryl" alone or as part of another substituent refers to a monovalent aromatic hydrocarbon group derived by removing a hydrogen atom from a single carbon atom of an aromatic ring system.

[0202] In a preferred variant, the term "aryl" includes three- to ten-membered monocyclic aryl or aryl groups or nine- to twelve-membered polycyclic aryl or aryl groups. In other still more preferred variants, carbon aryls include five-, six- or seven-membered monocyclic carbon aryls or nine- to twelve-membered bicyclic carbon aryls.

[0203] In a preferred embodiment according to the present invention, the aryl group includes 3 to 20 carbon atoms. In a preferred variant, the aryl moiety includes 6 to 15 ring atoms. In an even more preferred embodiment, the aryl group includes 6 to 10 carbon atoms.

[0204] According to the present invention, most preferably, it is a monocyclic C3 to C10 aryl group. Most preferably, it is a monocyclic C3 to C7 aryl group.

[0205] Typical aryl groups include but are not limited to benzene, phenyl, biphenyl, naphthyl (such as 1- or 2-naphthyl, tetrahydronaphthyl), fluorenyl, indenyl, and phenanthryl. Typical carbon aryl moieties also include but are not limited to groups derived from: aceanthrylene, acenaphthylene, acephenanthrylene, anthracene, azulene, benzene, chrysene, hexabenzobenzene, fluoranthene, fluorene, hexacene, hexaphene, hexalene, as-indacene, S-indacene, indane, indene, naphthalene, octacene, octaphene, octalene, ovalene, penta-2,4-diene, pentacene, pentalene, pentaphene, perylene, phenalene, phenanthrene, picene, pleiadene, pyrene, pyranthrene, rubicene, triphenylene, trinaphthalene, etc.

[0206] Preferred aromatic polycyclic aryl or aryl groups according to the present invention include but are not limited to naphthalene, biphenyl, etc.

[0207] The aryl moiety or group as defined above may be further substituted.

[0208] According to the present invention, the term "arylalkyl", alone or as part of another substituent, refers to an acyclic alkyl group in which one of the hydrogen atoms attached to a carbon atom (usually a terminal or sp carbon atom) is replaced by an aryl group as defined herein. In other words, arylalkyl can also be considered as an alkyl group substituted by an aryl group. Typical arylalkyl groups include but are not limited to benzyl, 2-phenylethane-1-yl, 2-phenylethene-1-yl, naphthylmethyl, 2-naphthylethane-1-yl, 2-naphthylethene-1-yl, naphthobenzyl, 2-naphthophenylethane-1-yl, etc.

[0209] The term "heteroarylalkyl", alone or as part of another substituent, refers to a cyclic alkyl group in which one of the hydrogen atoms attached to a carbon atom is replaced by a heteroaryl group. In a preferred embodiment according to the present invention, the heteroarylalkyl group is a 6- to 20-membered heteroarylalkyl, for example, the alkyl, alkenyl or alkynyl of the heteroarylalkyl is a C1 to C6 alkyl, and the heteroaryl group is a 5- to 15-membered heteroaryl group. In other embodiments, the heteroarylalkyl is a 6- to 13-membered heteroarylalkyl, for example the alkyl, alkenyl or alkynyl group is a C1 to C3 alkyl, and the heteroaryl group is a 5- to 10-membered heteroaryl.

[0210] According to the present invention, the term "heterocycloalkyl", alone or as part of another substituent, refers to a saturated or monounsaturated or polyunsaturated non-aromatic cyclic monovalent hydrocarbon group in which one or more carbon atoms are individually replaced by the same or different heteroatoms. Typical heteroatoms replacing carbon atoms include, but are not limited to, N, P, O, S, Si, etc. Typical heterocycloalkyls include, but are not limited to, groups derived from epoxides, azine rings, thiiranes, imidazolidines, morpholines, piperazines, piperidines, pyrazolidines, pyrrolidinones, quinuclidines, etc.

[0211] In a preferred embodiment according to the present invention, the heterocycloalkyl moiety or group includes 3 to 20 ring atoms. In a preferred variant, the heterocycloalkyl moiety includes 6 to 15 ring atoms. In an even more preferred embodiment, the heterocycloalkyl moiety includes 6 to 10 carbon atoms.

[0212] The heterocycloalkyl moiety can occur as a monocyclic compound having only a single ring, or as a polycyclic compound having two or more rings (such as bicyclic, tricyclic or spiro rings).

[0213] Preferably, the term "heterocycloalkyl" includes a three- to seven-membered saturated or monounsaturated or polyunsaturated heterocycloalkyl moiety including one, two, three or four heteroatoms selected from the group consisting of O, N and S. One or more heteroatoms can occupy any position in the heterocycloalkyl ring.

[0214] In a preferred variant, the term "heterocycloalkyl" includes a three- to ten-membered monocyclic heterocycloalkyl or a nine- to twelve-membered polycyclic heterocycloalkyl. In other still more preferred variants, the heterocycloalkyl moiety includes a five-, six- or seven-membered monocyclic heterocycloalkyl moiety or a nine- to twelve-membered bicyclic heterocycloalkyl moiety.

[0215] According to the present invention, most preferably a monocyclic heterocycloalkyl including 3 to 12 carbon atoms. Most preferably a monocyclic heterocycloalkyl having 5 to 7 ring atoms.

[0216] Exemplary heterocycloalkyl moieties include, but are not limited to: five- or six-membered saturated or monounsaturated heterocycloalkyls containing one or two nitrogen atoms and / or one oxygen or sulfur atom or one or two oxygen and / or sulfur atoms as ring members, including 2-tetrahydrofuranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl, 3-tetrahydrothienyl, 1-pyrrolidinyl, 2-pyrrolidinyl, 3-pyrrolidinyl, 3-isoxazolidinyl, 4-isoxazolidinyl, 5-isoxazolidinyl, 3-isothiazolidinyl, 4-isothiazolidinyl, 5-isothiazolidinyl, 3-pyrazolidinyl, 4-pyrazolidinyl, 5-pyrazolidinyl, 2-oxazolidinyl, 4-oxazolidinyl, 5-oxazolidinyl, 2-thiazolidinyl, 4-thiazolidinyl, 5-thiazolidinyl, 2-imidazolidinyl, 4-imidazolidinyl, 2-pyrrolin-2-yl, 2-pyrrolin-3-yl, 3-pyrrolin-2-yl, 3-pyrrolin-3-yl, 1-piperidinyl, 2-piperidinyl, 3-piperidinyl, 4-piperidinyl, 1,3-dioxan-5-yl, 2-tetrahydropyranyl, 4-tetrahydropyranyl, 2-tetrahydrothienyl, 3-hexahydropyridazinyl, 4-hexahydropyridazinyl, 2-hexahydropyrimidinyl, 4-hexahydropyrimidinyl, 5-hexahydropyrimidinyl, 2-piperazinyl, and the like.

[0217] The heterocycloalkyl moiety or group as defined above may be further substituted.

[0218] According to the present invention, the term "heteroaryl" per se or as part of another substituent refers to a monovalent heteroaromatic group obtained by removing a hydrogen atom from a single atom of a heteroaromatic ring system. Exemplary heteroaryl or heteroaryl groups include, but are not limited to, groups derived from the following: acridine, β-carboline, chroman, chromene, cinnoline, furan, imidazole, indazole, indole, indoline, indolizine, isobenzofuran, isochromene, isoindole, isoindoline, isoquinoline, isothiazole, isoxazole, naphthyridine, oxadiazole, oxazole, perimidine, phenanthridine, phenanthroline, phenazine, phthalazine, pteridine, purine, pyran, pyrazine, pyrazole, pyridazine, pyridine, pyrimidine, pyrrole, thiazole, thiophene, triazole, xanthene, and the like.

[0219] The heteroaryl moiety may occur as a monocyclic compound having only a single ring or as a polycyclic compound having two or more rings.

[0220] In a preferred variant, the term "heteroaryl" includes monocyclic heteroaryls from three to ten members or polycyclic heteroaryls from nine to twelve members. In still other more preferred variants, the heteroaryl moiety includes five-, six- or seven-membered monocyclic heteroaryl moieties or nine- to twelve-membered bicyclic heteroaryl moieties.

[0221] Preferably, the term "heteroaryl" includes monocyclic heteroaryls from three to seven members, including one, two, three or four heteroatoms selected from the group consisting of O, N and S. One or more heteroatoms may occupy any position in the heteroaryl ring.

[0222] In a preferred embodiment according to the present invention, the heteroaryl moiety or group comprises from 3 to 20 ring atoms. In an even more preferred variant, the heteroaryl moiety comprises from 6 to 15 ring atoms. In the most preferred embodiment, the heteroaryl group comprises from 6 to 10 ring atoms. According to the present invention, most preferably, it is a monocyclic C3 to C7 heteroaryl group.

[0223] Particularly preferred heteroaryl moieties or heteroaryl groups include, but are not limited to, groups derived from the following: furan, thiophene, pyrrole, benzothiophene, benzofuran, benzimidazole, indole, pyridine, pyrazole, quinoline, imidazole, oxazole, isoxazole, and pyrazine.

[0224] Five-membered aromatic heteroaryls containing one, two or three nitrogen atoms or one or two nitrogen atoms and one sulfur or oxygen atom as ring atoms in addition to carbon atoms include 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-pyrrolyl, 3-pyrrolyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 2-azolyl, 4-azolyl, 5-azolyl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 2-imidazolyl, 4-imidazolyl and 1,3,4-triazol-2-yl.

[0225] Five-membered aromatic heteroaryls containing one, two, three or four nitrogen atoms as ring atoms include 1-, 2- or 3-pyrrolyl, 1-, 3- or 4-pyrazolyl, 1-, 2- or 4-imidazolyl, 1,2,3-[1H]-triazol-1-yl, 1,2,3-[2H]-triazol-2-yl, 1,2,3-[1H]-triazol-4-yl, 1,2,3-[1H]-triazol-5-yl, 1,2,3-[2H]-triazol-4-yl, 1,2,4-[1H]-triazol-1-yl, 1,2,4-[1H]-triazol-3-yl, 1,2,4-[1H]-triazol-5-yl, 1,2,4-[4H]-triazol-4-yl, 1,2,4-[4H]-triazol-3-yl, [1H]-tetrazol-1-yl, [1H]-tetrazol-5-yl, [2H]-tetrazol-2-yl, [2H]-tetrazol-5-yl, etc.

[0226] Five-membered aromatic heteroaryls containing a heteroatom selected from oxygen or sulfur and optionally one, two or three nitrogen atoms as ring atoms include 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 3- or 4-isoxazolyl, 3- or 4-isothiazolyl, 2-, 4- or 5-oxazolyl, 2-, 4- or 5-thiazolyl, 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-2-yl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl and 3,4-oxadiazol-2-yl.

[0227] A six-membered heteroaryl containing one or two or one, two or three nitrogen atoms in addition to carbon atoms as ring atoms and including, for example, 2-pyridyl, 3-pyridyl, 4-pyridyl, 3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl, 2-pyrazinyl, 1,2,4-triazin-3-yl; 1,2,4-triazin-5-yl, 1,2,4-triazin-6-yl and 1,3,5-triazin-2-yl.

[0228] The heteroaryl moiety or group as defined above may be further substituted.

[0229] The term "C-spiro" in the context of the present application means a compound having at least two molecular rings that have only one common atom. The simplest spiro compounds are bicyclic (having only two rings) or have a bicyclic moiety as part of a larger ring system, in either case, the two rings being joined by a defined single common atom. Connecting a single common atom participating in the rings distinguishes spiro compounds from the following other bicyclic structures: isolated ring compounds without a connecting atom such as biphenyl, fused ring compounds having two rings joined by two adjacent atoms such as decalin and bridged ring compounds having two rings joined by two non-adjacent atoms such as norbornane. Spiro compounds can be all-carbon rings (all-carbon) or heterocycles (having one or more non-carbon atoms such as N, O and S). The common atom connecting the two (or sometimes three) rings is called the spiro atom. Preferably, the spiro atom is a carbon atom. More preferably, a C-spiro compound means a compound of all-carbon rings (all-carbon).

[0230] In the context of the present invention, the term "substituted" means that one or more hydrogen atoms of the indicated group are independently replaced by the same or different substituents. Additionally, the term "substituted" specifically provides one or more, i.e., two, three, four, five, six or more substituents commonly used in the art. However, it is well known that the substituents should be chosen such that these substituents do not adversely affect the useful properties or functions of the compound.

[0231] Suitably substituted groups in the context of the present invention preferably include halogen, perfluoroalkyl groups, perfluoroalkoxy groups, alkyl groups, alkenyl groups, alkynyl groups, hydroxy groups, oxo groups, mercapto groups, alkylthio groups, alkoxy groups, aryl groups or heteroaryl groups, aryloxy groups or heteroaryloxy groups, arylalkyl groups or heteroarylalkyl groups, arylalkoxy groups or heteroarylalkoxy groups, amino groups, alkyl groups and dialkylamino groups, carbamoyl groups, alkylcarbonyl groups, carboxy groups, alkoxycarbonyl groups, alkylaminocarbonyl groups, dialkylaminocarbonyl groups, arylcarbonyl groups, aryloxycarbonyl groups, alkylsulfonyl groups, arylsulfonyl groups, cycloalkyl groups, cyano groups, C1 to C6 alkylthio groups, arylthio groups, nitro groups, keto groups, acyl groups, boronic acid groups or boronyl groups, phosphoric acid groups or phosphonyl groups, sulfonamide groups, sulfonyl groups, sulfinyl groups and combinations thereof.

[0232] Substituents or groups of substituents that can be used to replace saturated carbon atoms in the indicated groups are more preferably but not limited to halogen, hydroxy, alkyl, alkenyl, alkynyl, alkoxy, -NH2, amino (primary, secondary or tertiary), nitro, mercapto, thioether, imine, cyano, acylamino, phosphonic acid, phosphine, carboxy, thiocarbonyl, sulfonyl, sulfonamide, keto, aldehyde, ester, acetyl, acetoxy, carbamoyl, oxygen (O); haloalkyl (e.g., trifluoromethyl); aminoacyl and aminoalkyl, carbocyclic cycloalkyl (which can be monocyclic or fused or unfused polycyclic (e.g., cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl)), or heterocycloalkyl (which can be monocyclic or fused or unfused polycyclic (e.g., pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl or thiazinyl)), carbocyclic or heterocyclic, monocyclic or fused or unfused polycyclic aryl (e.g., phenyl, naphthyl, pyrrolyl, indolyl, furyl, thienyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl, pyrazolyl, pyridyl, quinolinyl, isoquinolinyl, acridinyl, pyrazinyl, pyridazinyl, pyrimidinyl, benzimidazolyl, benzothienyl or benzofuryl), -CO2CH3, -CONH2, -OCH2CONH2; -SO2NH2, -OCHF2, -CF3, -OCF3.

[0233] According to the present invention, substituents used to replace a particular group or groups can in turn be further substituted, typically by one or more groups that are the same or different and are selected from the various groups indicated above and as defined in detail above. In the case of substituted combinations such as substituted arylalkyl, the aryl or alkyl group can be substituted, or both the aryl and alkyl groups can be substituted by one or more substituents.

[0234] In a preferred variant, Z in formula (V) is -O-R2' or amide'.

[0235] In another preferred variant, R1' in general formula (V) is CH2.

[0236] In another preferred variant, R1' in general formula (V) is C(alkyl)2.

[0237] In another preferred variant, R1' in general formula (V) is O.

[0238] In another preferred variant, R1' in general formula (V) is S.

[0239] In another preferred variant, R1' in general formula (V) is SO.

[0240] In another preferred variant, R1' in general formula (V) is SO2.

[0241] In another preferred variant, R1' in general formula (V) is NH.

[0242] In yet another preferred variant, R1' in general formula (V) is N(alkyl).

[0243] Most preferably, R1' in general formula (V) is CH2 or C(alkyl)2.

[0244] In a preferred variant, R2' in general formula (V) is H.

[0245] In another preferred variant, R2' in general formula (V) is methyl.

[0246] In another preferred variant, R2' in general formula (V) is ethyl.

[0247] In another preferred variant, R2' in general formula (V) is propyl.

[0248] In another preferred variant, R2' in general formula (V) is isopropyl.

[0249] In another preferred variant, R2' in general formula (V) is butyl.

[0250] In another preferred variant, R2' in general formula (V) is isobutyl.

[0251] In another preferred variant, R2' in general formula (V) is tert-butyl.

[0252] In another preferred variant, R2' in general formula (V) is

[0253] In another preferred variant, R2' in general formula (V) is

[0254] In a preferred variant, R2' in general formula (V) is (2-ethyl-hexyl).

[0255] In yet another preferred variant, R2' in general formula (V) is phenyl.

[0256] Most preferably, R2' in general formula (V) is H or ethyl or isopropyl or 2-ethylhexyl or phenyl.

[0257] In a preferred variant, amide' in general formula (V) is NH2.

[0258] In another preferred variant, amide' in general formula (V) is N(H-alkyl), where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0259] In another preferred variant, amide' in general formula (V) is N(alkyl)2, where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0260] In another preferred variant, amide' in general formula (V) is -N(O-alkyl)(alkyl) (Weinreb amide), where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0261] In yet another preferred variant, amide' in general formula (V) is -N(OH)(H) (isohydroxamic acid).

[0262] Most preferably, amide' in general formula (V) is NH2, N(methyl)2 or N(ethyl)2 or -N(O-alkyl)(alkyl) (Weinreb amide), where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl or -N(OH)(H) (isohydroxamic acid).

[0263] In a preferred variant, R3' in general formula (V) is H.

[0264] In another preferred variant, R3' in general formula (V) is methyl.

[0265] In another preferred variant, R3' in general formula (V) is ethyl.

[0266] In another preferred variant, R3' in general formula (V) is -O-methyl.

[0267] In another preferred variant, R3' in general formula (V) is -C(=O)-OH.

[0268] In another preferred variant, R3' in general formula (V) is -C(=O)-CH3.

[0269] In another preferred variant, R3' in the general formula (V) is -C(=O)-C3H7.

[0270] In still another preferred variant, R3' in the general formula (V) is -C(=O)-O-methyl.

[0271] Most preferably, R3' in the general formula (V) is H or methyl or -O-methyl.

[0272] In a preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of the general formula (V) is an acid compound or an ester compound represented by the general formula (VII)

[0273]

[0274] wherein R1', R2', R3', R4', R5' and R6' have the same meanings as defined herein for the general formula (V).

[0275] In a preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of the general formula (V) is an acid compound represented by the general formula (VII-acid)

[0276]

[0277] wherein R1', R3', R4', R5' and R6' have the same meanings as defined herein for the general formula (V).

[0278] Mycosporine-like amino acid compounds are particularly photo-stable and temperature-stable compounds, and exhibit stability in pH solutions or different types of emulsions and do not degrade.

[0279] In particular, mycosporine-like amino acid compounds having an acid group have better pH stability in a wider pH range compared to their corresponding hydrolyzable ester compounds, and are thus unstable in alkaline solutions with a pH above 9.

[0280] In addition, the mycosporine-like amino acid compounds also have better solubility in water compared to their corresponding ester compounds. Due to their better solubility in water, the mycosporine-like amino acid compounds can be incorporated into the aqueous phase of the emulsion at a higher concentration, thereby improving the strengthening effect of the film-forming agent.

[0281] In a preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of the general formula (V) is an ester compound represented by the general formula (VII-ester)

[0282]

[0283] wherein R1', R3', R4', R5' and R6' have the same meanings as defined herein for general formula (V).

[0284] Preferably, the alkyl residue in general formula (VII-ester) is methyl or ethyl or propyl or isopropyl or butyl or isobutyl or tert-butyl. Most preferably, the alkyl residue in general formula (VII-ester) is methyl. This ester compound is particularly stable.

[0285] In an alternative preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of general formula (V) is an amide compound represented by general formula (VIII)

[0286]

[0287] wherein R1', amide', R3', R4', R5' and R6' have the same meanings as defined herein for general formula (V).

[0288] In a more preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of general formula (V) is an amide compound represented by general formula (VIII-amide)

[0289]

[0290] wherein R1', R3', R4', R5' and R6' have the same meanings as defined herein for general formula (V), and R11' and R12' are independently selected from the group consisting of H, OH and alkyl.

[0291] In a preferred variant according to the first aspect of the present invention, in general formula (VIII-amide), R11' and / or R12' is H.

[0292] In another preferred variant, the R11' alkyl and R12' alkyl in general formula (VIII-amide) are independently selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0293] Preferably, each of R11' and / or R12' in general formula (VIII-amide) is H or each is methyl.

[0294] In an even more preferred variant, the mycosporine-like amino acid compound (b) of general formula (V) is a Weinreb amide compound represented by general formula (VIII-Weinreb amide)

[0295]

[0296] wherein R1', R3', R4', R5' and R6' have the same meanings as defined herein for general formula (V).

[0297] In a preferred variant, the alkyl residue in general formula (VIII - Weinreb amide) is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert - butyl, and more preferably, the alkyl residue is methyl.

[0298] Alternatively, in an even more preferred variant, the mycosporine - like amino acid compound (b) of general formula (V) is a hydroxamic acid compound represented by general formula (VIII - hydroxamic acid derivative)

[0299]

[0300] wherein R1', R3', R4', R5' and R6' have the same meanings as defined herein for general formula (V).

[0301] Alternatively, in an even more preferred variant, the mycosporine - like amino acid compound (b) of general formula (V) is an alkylated hydroxamic acid compound represented by general formula (VIII - alkylated hydroxamic acid derivative)

[0302]

[0303] wherein R1', R3', R4', R5' and R6' have the same meanings as defined herein for general formula (V).

[0304] In a preferred variant, the alkyl residue in general formula (VIII - alkylated hydroxamic acid derivative) is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert - butyl, and more preferably, the alkyl is methyl.

[0305] In a preferred alternative variant, the mycosporine - like amino acid compound (b) is represented by general formula (A)

[0306]

[0307] wherein R1', R3', R4', R5' and R6' have the same meanings as defined herein for general formula (V).

[0308] In the present invention, the same preferred variants as defined herein for the mycosporine - like amino acid compound according to general formula (V) similarly apply to the mycosporine - like amino acid compounds according to general formula (VII) or (VIII) and their variants or general formula (A).

[0309] In another preferred variant, R1'' in general formula (VI) is CH2.

[0310] In another preferred variant, R1” in general formula (VI) is C(alkyl)2.

[0311] In another preferred variant, R1” in general formula (VI) is O.

[0312] In another preferred variant, R1” in general formula (VI) is S.

[0313] In another preferred variant, R1” in general formula (VI) is SO.

[0314] In another preferred variant, R1” in general formula (VI) is SO2.

[0315] In another preferred variant, R1” in general formula (VI) is NH.

[0316] In yet another preferred variant, R1” in general formula (VI) is N(alkyl).

[0317] Most preferably, R1” in general formula (VI) is CH2 or C(alkyl)2.

[0318] In a preferred variant, R2” in general formula (VI) is -CH2-OH.

[0319] In another preferred variant, R2” in general formula (VI) is -C(=O)-O-Y.

[0320] In another preferred variant, R2” in general formula (VI) is -C(=O)-amide”.

[0321] Most preferably, R2” in general formula (VI) is -C(=O)-O-Y or -C(=O)-amide”.

[0322] In another preferred variant, X in general formula (VI) is CH2.

[0323] In another preferred variant, X in general formula (VI) is C=O.

[0324] In another preferred variant, X in general formula (VI) is O.

[0325] In another preferred variant, X in general formula (VI) is S.

[0326] In another preferred variant, X in general formula (VI) is SO.

[0327] In another preferred variant, X in general formula (VI) is SO2.

[0328] In another preferred variant, X in general formula (VI) is NH.

[0329] In still another preferred variant, X in formula (VI) is N(alkyl), where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl.

[0330] Most preferably, X in formula (VI) is S, SO, or SO2.

[0331] In a preferred variant, Y in formula (VI) is H.

[0332] In another preferred variant, Y in formula (VI) is methyl.

[0333] In another preferred variant, Y in formula (VI) is ethyl.

[0334] In another preferred variant, Y in formula (VI) is propyl.

[0335] In another preferred variant, Y in formula (VI) is isopropyl.

[0336] In another preferred variant, Y in formula (VI) is butyl.

[0337] In another preferred variant, Y in formula (VI) is isobutyl.

[0338] In another preferred variant, Y in formula (VI) is tert-butyl.

[0339] In another preferred variant, Y in formula (VI) is

[0340] In another preferred variant, Y in formula (VI) is

[0341] In a preferred variant, Y in formula (VI) is (2-ethyl-hexyl).

[0342] In still another preferred variant, Y in formula (VI) is phenyl.

[0343] Most preferably, Y in formula (VI) is H, or ethyl, or isopropyl, or 2-ethylhexyl, or phenyl.

[0344] In a preferred variant, the "amide" in formula (VI) is NH2.

[0345] In another preferred variant, the "amide" in formula (VI) is N(H alkyl), where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl.

[0346] In another preferred variant, the amide in formula (VI) is N(alkyl)2, where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl.

[0347] In another preferred variant, the amide in formula (VI) is -N(O-alkyl)(alkyl) (Weinreb amide), where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl.

[0348] In yet another preferred variant, the amide in formula (V) is -N(OH)(H) (hydroxamic acid).

[0349] Most preferably, the amide in formula (V) is NH2, N(methyl)2, or N(ethyl)2, or -N(O-alkyl)(alkyl) (Weinreb amide), where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl, or -N(OH)(H) (hydroxamic acid).

[0350] In a more preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) is an alcohol compound represented by formula (IX-alcohol)

[0351]

[0352] wherein R1”, X, R4”, R5” and R6” have the same meanings as defined herein for formula (VI).

[0353] Alternatively, in a more preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of formula (VI) is an acid compound represented by formula (IX-acid)

[0354]

[0355] wherein R1”, X, R4”, R5” and R6” have the same meanings as defined herein for formula (VI).

[0356] Alternatively, in a more preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of formula (VI) is an ester compound represented by formula (VII-ester)

[0357]

[0358] wherein R1”, X, R4”, R5” and R6” have the same meanings as defined herein for formula (VI).

[0359] Preferably, the alkyl residue in the general formula (VII-ester) is methyl or ethyl or propyl or isobutyl or butyl or isobutyl or tert-butyl, and more preferably, the alkyl residue is methyl.

[0360] In an alternative more preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of the general formula (VI) is an amide compound represented by the general formula (X)

[0361]

[0362] wherein R1”, amide”, X, R4”, R5” and R6” have the same meanings as defined herein for the general formula (VI).

[0363] In a more preferred alternative variant according to the first aspect of the present invention, the mycosporine-like amino acid compound (b) of the general formula (VI) is an amide compound represented by the general formula (X-amide)

[0364]

[0365] wherein R1”, X, R4”, R5” and R6” have the same meanings as defined herein for the general formula (VI), and R11” and R12” are independently selected from the group consisting of H, OH and alkyl.

[0366] In a preferred variant according to the first aspect of the present invention, in the general formula (X-amide), R11” and / or R12” is H.

[0367] Preferably, the R11” alkyl and R12” alkyl in the general formula (X-amide) are methyl or ethyl or propyl or isopropyl or butyl or isobutyl or tert-butyl.

[0368] Preferably, R11” and R12” in the general formula (X-amide) are each H or each methyl.

[0369] In an even more preferred variant, the mycosporine-like amino acid compound (b) of the general formula (VI) is a Weinreb amide compound represented by the general formula (X-Weinreb amide)

[0370]

[0371] wherein R1”, X, R4”, R5” and R6” have the same meanings as defined herein for the general formula (VI).

[0372] In a preferred variant, the alkyl residue in the general formula (X-Weinreb amide) is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl, and more preferably, the alkyl residue is methyl.

[0373] Alternatively, in an even more preferred variant, the mycosporine - like amino acid compound (b) of general formula (VI) is a hydroxamic acid compound represented by general formula (X - hydroxamic acid derivative)

[0374]

[0375] wherein R1″, X, R4″, R5″ and R6″ have the same meanings as defined above for general formula (VI).

[0376] Alternatively, in yet another preferred variant, the mycosporine - like amino acid compound (b) of general formula (VI) is an alkylated hydroxamic acid compound represented by general formula (VIII - alkylated hydroxamic acid derivative)

[0377]

[0378] wherein R1″, X, R4″, R5″ and R6″ have the same meanings as defined herein for general formula (VI).

[0379] In a preferred variant, the alkyl residue in general formula (X - alkylated hydroxamic acid derivative) is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert - butyl, and more preferably, the alkyl residue is methyl.

[0380] In the present invention, the same preferred variants as defined herein for the mycosporine - like amino acid compounds according to general formula (VI) similarly apply to the mycosporine - like amino acid compounds according to general formula (IX) or (X) and their variants.

[0381] Hereinafter, the term "according to general formula YZ and their variants" includes any sub - formula of the said general formula as disclosed herein. Thus, the variants of general formula (V) and (VI) as defined herein include formula (VII), formula (VIII), formula (IX) and formula (X) as defined herein. The variants of general formula (VII) and (VIII) as defined herein include sub - formula (VII - acid), sub - formula (VII - ester), sub - formula (VIII - amide), sub - formula (VIII - Weinreb amide), sub - formula (VIII - hydroxamic acid derivative) and sub - formula (VIII - alkylated hydroxamic acid derivative) as defined herein. The variants of general formula (IX) and (X) as defined herein include formula (IX - acid), formula (IX - ester), formula (X - amide), formula (X - Weinreb amide), formula (X - hydroxamic acid derivative) and formula (X - alkylated hydroxamic acid derivative) as defined herein.

[0382] In another preferred variant, in general formulas (VI), (IX), (X) and their variants, X is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted C(alkyl)2, unsubstituted or substituted CH(alkenyl), unsubstituted or substituted CH(alkynyl), unsubstituted or substituted CH(alkoxy), unsubstituted or substituted CH(alkylthio), unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), -CR7”R8”, C=O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl), unsubstituted or substituted N(heteroaryl) and unsubstituted or substituted C-spiro ring.

[0383] In another preferred variant according to the first aspect of the present invention, the mycosporine-like amino acid compound is a compound according to general formula (V), wherein

[0384] -Z is -O-R2' or amide'; and / or

[0385] -R1' is selected from the group consisting of: CH2, C(alkyl)2, O, S, SO, SO2, NH and N(alkyl); and / or

[0386] -R2' is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethyl-hexyl) and phenyl; or

[0387] -amide' is selected from the group consisting of: NH2, NH(alkyl), N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide) and -N(OH)(H) (hydroxamic acid); and / or

[0388] -R3' is selected from the group consisting of: H, methyl, ethyl, -O-methyl, -C(=O)-OH, -C(=O)-CH3, -C(=O)-C3H7 and -C(=O)-O-methyl; and / or

[0389] -the substituents R4', R5' and R6' have the same meanings as defined in formula (V);

[0390] - wherein the alkyl group is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0391] In another preferred variant according to the first aspect of the present invention, such mycosporine-like amino acid compound is a compound according to general formula (VII) or (VIII), wherein

[0392] - R1' is selected from the group consisting of CH2, C(alkyl)2, O, S, SO, SO2, NH and N(alkyl); and / or

[0393] - R2' is selected from the group consisting of H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethyl-hexyl) and phenyl; or

[0394] - amide' is selected from the group consisting of NH2, N(H alkyl), N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide) and -N(OH)(H) (hydroxamic acid); and / or

[0395] - R3' is selected from the group consisting of H, methyl, ethyl, -O-methyl, -C(=O)-OH, -C(=O)-CH3, -C(=O)-C3H7 and -C(=O)-O-methyl; and / or

[0396] - the substituents R4', R5' and R6' have the same meanings as defined in formula (V);

[0397] - wherein the alkyl group is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0398] In another preferred variant according to the first aspect of the present invention, such mycosporine-like amino acid compound is a compound according to general formula (VI), wherein

[0399] - R1” is selected from the group consisting of CH2, C(alkyl)2, O, S, SO, SO2, NH and N(alkyl); and / or

[0400] - R2” is selected from the group consisting of -CH2-OH, -C(=O)-O-Y and -C(=O)-amide”; and / or

[0401] - X is selected from the group consisting of CH2, C=O, O, S, SO, SO2, NH and N(alkyl); and / or

[0402] -Y is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethyl-hexyl) and phenyl; and / or

[0403] -amide is selected from the group consisting of: NH2, NH(alkyl), N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide) and -N(OH)(H) (hydroxamic acid); and / or

[0404] -the substituents R4″, R5″ and R6″ have the same meanings as defined in formula (VI);

[0405] -wherein alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0406] In another preferred variant according to the first aspect of the present invention, such mycosporine-like amino acid compound is a compound according to general formula (V), wherein

[0407] -Z is -O-R2′ or amide′; and / or

[0408] -R1′ is selected from the group consisting of CH2 and C(methyl)2; and / or

[0409] -R2′ is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethyl-hexyl) and phenyl; or

[0410] -amide′ is selected from the group consisting of: NH2, NH(alkyl), N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide) and -N(OH)(H) (hydroxamic acid); and / or

[0411] -R3′ is selected from the group consisting of: H, methyl, ethyl, -O-methyl, -C(=O)-OH, -C(=O)-CH3, -C(=O)-C3H7 and -C(=O)-O-methyl; and / or

[0412] -the substituents R4′, R5′ and R6′ have the same meanings as defined in formula (V);

[0413] -wherein alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0414] In another preferred variant according to the first aspect of the present invention, such mycosporine-like amino acid compound is a compound according to general formula (VII) or (VIII), wherein

[0415] - R1' is selected from the group consisting of CH2 and C(methyl)2; and / or

[0416] - R2' is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert - butyl, (2 - ethyl - hexyl) and phenyl; or

[0417] - amide' is selected from the group consisting of: NH2, NH(alkyl), N(alkyl)2, - N(O - alkyl)(alkyl) (Weinreb amide) and - N(OH)(H) (hydroxamic acid); and / or

[0418] - R3' is selected from the group consisting of: H, methyl, ethyl, - O - methyl, - C(=O)-OH, - C(=O)-CH3, - C(=O)-C3H7 and - C(=O)-O - methyl; and / or

[0419] - the substituents R4', R5' and R6' have the same meanings as defined in formula (V);

[0420] - wherein alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert - butyl.

[0421] In another preferred variant according to the first aspect of the present invention, such mycosporine - like amino acid compounds are compounds according to general formula (VI), wherein

[0422] - R1” is selected from the group consisting of CH2 and C(methyl)2; and / or

[0423] - R2” is selected from the group consisting of: - CH2 - OH, - C(=O)-O - Y and - C(=O)-amide”; and / or

[0424] - X is selected from the group consisting of: CH2, C=O, O, S, SO, SO2, NH and N(alkyl); and / or

[0425] - Y is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert - butyl, (2 - ethyl - hexyl) and phenyl; and / or

[0426] - amide” is selected from the group consisting of: NH2, NH(alkyl), N(alkyl)2, - N(O - alkyl)(alkyl) (Weinreb amide) and - N(OH)(H) (hydroxamic acid); and / or

[0427] - The substituents R4″, R5″ and R6″ have the same meanings as defined in formula (VI);

[0428] - wherein the alkyl group is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert - butyl.

[0429] In an even more preferred variant according to the invention, the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprises at least one mycosporine - like amino acid compound selected from the group consisting of the following compounds I - 1 to I - 128 according to general formula (V) and II - 1 to II - 192 according to general formula (VI):

[0430] Table 1 :

[0431]

[0432]

[0433]

[0434]

[0435]

[0436]

[0437]

[0438]

[0439] or a tautomer or stereoisomeric salt of the above - mentioned compounds, or any mixture of the above - mentioned compounds.

[0440] Among the mycosporine - like amino acid compounds in Table 1, the benzene ring can be unsubstituted or substituted. The substituents R4′, R5′, R6′, R4″, R5″, R6″, amide′, Y, amide″ and alkyl have the same meanings as previously defined for the mycosporine - like amino acid compounds according to general formula (V) or (VI).

[0441] Particularly preferred are those mycosporine - like amino acid compounds, wherein in general formula (V), R1′ is CH2 or C(CH3)2, or wherein in general formula (VI), R1″ is CH2 or C(CH3)2:

[0442] Table 2 :

[0443]

[0444]

[0445]

[0446] or a tautomer or stereoisomer or salt of the above compound or any mixture of the above compounds.

[0447] In the mycosporine - like amino acid compounds of Table 2, the benzene ring may be unsubstituted or substituted. The substituents R4', R5', R6', R4'', R5'', R6'', amide', Y, amide'' and alkyl have the same meanings as defined previously for the mycosporine - like amino acid compounds according to general formula (V) or (VI).

[0448] Preferably, in the mycosporine - like amino acid compounds according to general formula (V) and general formula (VI) specified in Table 1 and Table 2

[0449] - R2' is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert - butyl, (2 - ethylhexyl) and phenyl;

[0450] - amide' is selected from the group consisting of: NH2, NH(alkyl), N(alkyl)2, - N(O - alkyl)(alkyl) (Weinreb amide) and - N(OH)(H) (isohydroxamic acid);

[0451] - Y is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert - butyl, (2 - ethylhexyl) and phenyl;

[0452] - amide'' is selected from the group consisting of: NH2, NH(alkyl), N(alkyl)2, - N(O - alkyl)(alkyl) (Weinreb amide) and - N(OH)(H) (isohydroxamic acid); and

[0453] - alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert - butyl.

[0454] In the most preferred variant according to the first aspect of the present invention, the mycosporine - like amino acid compound is a compound according to general formula (V) and its variant or a compound according to formula (VI) and its variant, wherein R1' or R1'' is CH2. Such mycosporine - like amino acid compounds have particularly good water solubility.

[0455] In still another preferred variant according to the first aspect of the present invention, the mycosporine - like amino acid compound is a compound according to general formula (VI), (IX), (X) and their variants, wherein X is selected from the group consisting of S, SO and SO2.

[0456] This mycosporine - like amino acid compound alters the UV absorption curve of a sunscreen product or a cosmetic or a pharmaceutical preparation and broadens the UV absorption spectrum of the formulation across the entire UV radiation spectrum.

[0457] In an even more preferred variant according to the first aspect of the present invention, the mycosporine - like amino acid compound is a compound according to general formulas (VI), (IX), (X) and their variants, where X is S. However, the S atoms in the composition are prone to oxidation.

[0458] In a more preferred variant according to the first aspect of the present invention, the mycosporine - like amino acid compound is a compound according to general formulas (VI), (IX), (X) and their variants, where X is SO or SO2. This mycosporine - like amino acid compound is particularly stable due to their oxidation state.

[0459] In yet another preferred variant according to the present invention, in general formulas (V) to (X) and their variants, n is 1.

[0460] In a more preferred variant according to the first aspect of the present invention, the mycosporine - like amino acid compound is a compound according to general formula (V), where

[0461] -Z is -O-R2' or amide'; and / or

[0462] -R1' is CH2 or C(methyl)2; and / or

[0463] -R2' is H or ethyl or isopropyl or 2 - ethylhexyl or phenyl; or

[0464] -amide' is NH2 or N(methyl)2 or N(ethyl)2 or -N(O - alkyl)(alkyl)(Weinreb amide) or -N(OH)(H)(isohydroxamic acid); and / or

[0465] -R3' is H or -O - methyl or -C(=O)-OH or -C(=O)-CH3 or -C(=O)-O - methyl; and / or

[0466] -the substituents R4', R5' and R6' have the same meanings as defined in formula (V);

[0467] -where the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert - butyl.

[0468] In a more preferred variant according to the first aspect of the present invention, the mycosporine - like amino acid compound is a compound according to general formula (VII) or (VIII), where

[0469] - R1' is CH2 or C(methyl)2; and / or

[0470] - R2' is H or ethyl or isopropyl or 2-ethylhexyl or phenyl; or

[0471] - amide' is NH2 or N(methyl)2 or N(ethyl)2 or -N(O-alkyl)(alkyl) (Weinreb amide) or -N(OH)(H) (isohydroxamic acid); and / or

[0472] - R3' is H or -O-methyl or -C(=O)-OH or -C(=O)-CH3 or -C(=O)-O-methyl; and / or

[0473] - the substituents R4', R5' and R6' have the same meanings as defined in formula (V);

[0474] - wherein the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

[0475] In a more preferred variant of the first aspect according to the invention, the mycosporine-like amino acid compound is a compound according to general formula (VI), wherein

[0476] - R1” is CH2 or C(methyl)2; and / or

[0477] - R2” is -C(=O)-O-Y or -C(=O)-amide”; and / or

[0478] - X is S, SO or SO2; and / or

[0479] - Y is H or ethyl or isopropyl or 2-ethylhexyl or phenyl; or

[0480] - amide” is NH2 or N(methyl)2 or N(ethyl)2 or -N(O-alkyl)(alkyl) (Weinreb amide) or -N(OH)(H) (isohydroxamic acid); and / or

[0481] - the substituents R4”, R5” and R6” have the same meanings as defined in formula (VI);

[0482] - wherein the alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and butyl.

[0483] The benzene ring in the mycosporine-like amino acid compounds according to general formulas (V) to (X) and their variants may be unsubstituted or substituted.

[0484] In a preferred variant, the benzene ring in the mycosporine - like amino acid compound according to general formulae (V) to (X) is unsubstituted, i.e., the substituents R4', R5' and R6' on the benzene ring in general formula (V) are H; or the substituents R4'', R5'' and R6'' on the benzene ring in general formula (VI) are H.

[0485] In another preferred variant, the benzene ring in the mycosporine - like amino acid compound according to general formulae (V) to (X) and their variants is substituted.

[0486] Most preferably, the benzene ring in the mycosporine - like amino acid compound according to general formulae (V), (VII), (VIII) and their variants is unsubstituted, i.e., the substituents R4', R5' and R6' are each H. Alternatively, most preferably, the benzene ring in the mycosporine - like amino acid compound according to general formulae (VI), (IX), (X) and their variants is unsubstituted, i.e., the substituents R4'', R5'' and R6'' are each H. The compound has improved water solubility.

[0487] Preferably, the benzene ring in the mycosporine - like amino acid compound according to general formulae (V) to (X) and their variants is mono - substituted, di - substituted or tri - substituted.

[0488] In an even more preferred variant according to the first aspect of the present invention, the mycosporine - like amino acid compound is a compound according to general formulae (V), (VII) and (VIII) and their variants, wherein the substituents R4', R5' and R6', which may be the same or different, are independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl or tert - butyl, alkoxy, preferably O - methyl, O - ethyl or O - butyl, - S(=O)2OH and sulfonyl.

[0489] Even more preferably, the substituents R4', R5' and R6', which may be the same or different, in general formulae (V), (VII), (VIII) and their variants are independently selected from the group consisting of H, OH, methyl, O - methyl, - S(=O)2OH and sulfonyl.

[0490] Alternatively, the mycosporine - like amino acid compound is a mycosporine - like amino acid compound according to general formulae (VI), (IX) and (X) and their variants, wherein the substituents R4'', R5'' and R6'', which may be the same or different, are independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert - butyl, alkoxy, preferably O - methyl, O - ethyl or O - butyl, - S(=O)2OH and sulfonyl.

[0491] Still more preferably, the substituents R4', R5' and R6', which may be the same or different in general formulas (VI), (IX), (X) and their variants, are independently selected from the group consisting of H, OH, methyl, O-methyl, -S(=O)2OH and sulfonyl group.

[0492] In general formulas (V) to (X) and their variants, the following substitution patterns are particularly preferred:

[0493] R4' = H and R5' = H and R6' = H; or

[0494] R4' = H and R5' = H and R6' = OH; or

[0495] R4' = H and R5' = H and R6' = methyl; or

[0496] R4' = H and R5' = H and R6' = O-methyl; or

[0497] R4' = H and R5' = H and R6' = -S(=O)2OH; or

[0498] R4' = H and R5' = H and R6' = sulfonyl group; or

[0499] R4' = H and R5' = OH and R6' = H; or

[0500] R4' = H and R5' = OH and R6' = OH; or

[0501] R4' = H and R5' = OH and R6' = methyl; or

[0502] R4' = H and R5' = OH and R6' = O-methyl; or

[0503] R4' = H and R5' = OH and R6' = -S(=O)2OH; or

[0504] R4' = H and R5' = OH and R6' = sulfonyl group; or

[0505] R4' = H and R5' = methyl and R6' = H; or

[0506] R4' = H and R5' = methyl and R6' = OH; or

[0507] R4' = H and R5' = methyl and R6' = methyl; or

[0508] R4' = H and R5' = methyl and R6' = O-methyl; or

[0509] R4' = H and R5' = methyl and R6' = -S(=O)2OH; or

[0510] R4' = H and R5' = methyl and R6' = sulfonyl; or

[0511] R4' = H and R5' = O-methyl and R6' = H; or

[0512] R4' = H and R5' = O-methyl and R6' = OH; or

[0513] R4' = H and R5' = O-methyl and R6' = methyl; or

[0514] R4' = H and R5' = O-methyl and R6' = O-methyl; or

[0515] R4' = H and R5' = O-methyl and R6' = -S(=O)2OH; or

[0516] R4' = H and R5' = O-methyl and R6' = sulfonyl; or

[0517] R4' = H and R5' = -S(=O)2OH and R6' = H; or

[0518] R4' = H and R5' = -S(=O)2OH and R6' = OH; or

[0519] R4' = H and R5' = -S(=O)2OH and R6' = methyl; or

[0520] R4' = H and R5' = -S(=O)2OH and R6' = O-methyl; or

[0521] R4' = H and R5' = -S(=O)2OH and R6' = -S(=O)2OH; or

[0522] R4' = H and R5' = -S(=O)2OH and R6' = sulfonyl; or

[0523] R4' = H and R5' = sulfonyl and R6' = H; or

[0524] R4' = H and R5' = sulfonyl and R6' = OH; or

[0525] R4' = H and R5' = sulfonyl and R6' = methyl; or

[0526] R4' = H and R5' = sulfonyl and R6' = O-methyl; or

[0527] R4' = H and R5' = sulfonyl and R6' = -S(=O)2OH; or

[0528] R4' = H and R5' = sulfonyl and R6' = sulfonyl; or

[0529] R4' = OH and R5' = H and R6' = H; or

[0530] R4' = OH and R5' = H and R6' = OH; or

[0531] R4' = OH and R5' = H and R6' = methyl; or

[0532] R4' = OH and R5' = H and R6' = O-methyl; or

[0533] R4' = OH and R5' = H and R6' = -S(=O)2OH; or

[0534] R4' = OH and R5' = H and R6' = sulfonyl; or

[0535] R4' = OH and R5' = OH and R6' = H; or

[0536] R4' = OH and R5' = OH and R6' = OH; or

[0537] R4' = OH and R5' = OH and R6' = methyl; or

[0538] R4' = OH and R5' = OH and R6' = O-methyl; or

[0539] R4' = OH and R5' = OH and R6' = -S(=O)2OH; or

[0540] R4' = OH and R5' = OH and R6' = sulfonyl; or

[0541] R4' = OH and R5' = methyl and R6' = H; or

[0542] R4' = OH and R5' = methyl and R6' = OH; or

[0543] R4' = OH and R5' = methyl and R6' = methyl; or

[0544] R4' = OH and R5' = methyl and R6' = O-methyl; or

[0545] R4' = OH and R5' = methyl and R6' = -S(=O)2OH; or

[0546] R4' = OH and R5' = methyl and R6' = sulfonyl; or

[0547] R4' = OH and R5' = O - methyl and R6' = H; or

[0548] R4' = OH and R5' = O - methyl and R6' = OH; or

[0549] R4' = OH and R5' = O - methyl and R6' = methyl; or

[0550] R4' = OH and R5' = O - methyl and R6' = O - methyl; or

[0551] R4' = OH and R5' = O - methyl and R6' = -S(=O)2OH; or

[0552] R4' = OH and R5' = O - methyl and R6' = sulfonyl; or

[0553] R4' = OH and R5' = -S(=O)2OH and R6' = H; or

[0554] R4' = OH and R5' = -S(=O)2OH and R6' = OH; or

[0555] R4' = OH and R5' = -S(=O)2OH and R6' = methyl; or

[0556] R4' = OH and R5' = -S(=O)2OH and R6' = O - methyl; or

[0557] R4' = OH and R5' = -S(=O)2OH and R6' = -S(=O)2OH; or

[0558] R4' = OH and R5' = -S(=O)2OH and R6' = sulfonyl; or

[0559] R4' = OH and R5' = sulfonyl and R6' = H; or

[0560] R4' = OH and R5' = sulfonyl and R6' = OH; or

[0561] R4' = OH and R5' = sulfonyl and R6' = methyl; or

[0562] R4' = OH and R5' = sulfonyl and R6' = O - methyl; or

[0563] R4' = OH and R5' = sulfonyl and R6' = -S(=O)2OH; or

[0564] R4' = OH and R5' = sulfonyl and R6' = sulfonyl; or

[0565] R4' = methyl and R5' = H and R6' = H; or

[0566] R4' = methyl and R5' = H and R6' = OH; or

[0567] R4' = methyl and R5' = H and R6' = methyl; or

[0568] R4' = methyl and R5' = H and R6' = O - methyl; or

[0569] R4' = methyl and R5' = H and R6' = -S(=O)2OH; or

[0570] R4' = methyl and R5' = H and R6' = sulfonyl; or

[0571] R4' = methyl and R5' = OH and R6' = H; or

[0572] R4' = methyl and R5' = OH and R6' = OH; or

[0573] R4' = methyl and R5' = OH and R6' = methyl; or

[0574] R4' = methyl and R5' = OH and R6' = O - methyl; or

[0575] R4' = methyl and R5' = OH and R6' = -S(=O)2OH; or

[0576] R4' = methyl and R5' = OH and R6' = sulfonyl; or

[0577] R4' = methyl and R5' = methyl and R6' = H; or

[0578] R4' = methyl and R5' = methyl and R6' = OH; or

[0579] R4' = methyl and R5' = methyl and R6' = methyl; or

[0580] R4' = methyl and R5' = methyl and R6' = O - methyl; or

[0581] R4' = methyl and R5' = methyl and R6' = -S(=O)2OH; or

[0582] R4' = methyl and R5' = methyl and R6' = sulfonyl; or

[0583] R4' = methyl, R5' = O - methyl and R6' = H; or

[0584] R4' = methyl, R5' = O - methyl and R6' = OH; or

[0585] R4' = methyl, R5' = O - methyl and R6' = methyl; or

[0586] R4' = methyl, R5' = O - methyl and R6' = O - methyl; or

[0587] R4' = methyl, R5' = O - methyl and R6' = -S(=O)2OH; or

[0588] R4' = methyl, R5' = O - methyl and R6' = sulfonyl; or

[0589] R4' = methyl, R5' = -S(=O)2OH and R6' = H; or

[0590] R4' = methyl, R5' = -S(=O)2OH and R6' = OH; or

[0591] R4' = methyl, R5' = -S(=O)2OH and R6' = methyl; or

[0592] R4' = methyl, R5' = -S(=O)2OH and R6' = O - methyl; or

[0593] R4' = methyl, R5' = -S(=O)2OH and R6' = -S(=O)2OH; or

[0594] R4' = methyl, R5' = -S(=O)2OH and R6' = sulfonyl; or

[0595] R4' = methyl, R5' = sulfonyl and R6' = H; or

[0596] R4' = methyl, R5' = sulfonyl and R6' = OH; or

[0597] R4' = methyl, R5' = sulfonyl and R6' = methyl; or

[0598] R4' = methyl, R5' = sulfonyl and R6' = O - methyl; or

[0599] R4' = methyl, R5' = sulfonyl and R6' = -S(=O)2OH; or

[0600] R4' = methyl, R5' = sulfonyl and R6' = sulfonyl; or

[0601] R4' = O-methyl, R5' = H, and R6' = H; or

[0602] R4' = O-methyl, R5' = H, and R6' = OH; or

[0603] R4' = O-methyl, R5' = H, and R6' = methyl; or

[0604] R4' = O-methyl, R5' = H, and R6' = O-methyl; or

[0605] R4' = O-methyl, R5' = H, and R6' = -S(=O)2OH; or

[0606] R4' = O-methyl, R5' = H, and R6' = sulfonyl; or

[0607] R4' = O-methyl, R5' = OH, and R6' = H; or

[0608] R4' = O-methyl, R5' = OH, and R6' = OH; or

[0609] R4' = O-methyl, R5' = OH, and R6' = methyl; or

[0610] R4' = O-methyl, R5' = OH, and R6' = O-methyl; or

[0611] R4' = O-methyl, R5' = OH, and R6' = -S(=O)2OH; or

[0612] R4' = O-methyl, R5' = OH, and R6' = sulfonyl; or

[0613] R4' = O-methyl, R5' = methyl, and R6' = H; or

[0614] R4' = O-methyl, R5' = methyl, and R6' = OH; or

[0615] R4' = O-methyl, R5' = methyl, and R6' = methyl; or

[0616] R4' = O-methyl, R5' = methyl, and R6' = O-methyl; or

[0617] R4' = O-methyl, R5' = methyl, and R6' = -S(=O)2OH; or

[0618] R4' = O-methyl, R5' = methyl, and R6' = sulfonyl; or

[0619] R4' = O-methyl and R5' = O-methyl and R6' = H; or

[0620] R4' = O-methyl and R5' = O-methyl and R6' = OH; or

[0621] R4' = O-methyl and R5' = O-methyl and R6' = methyl; or

[0622] R4' = O-methyl and R5' = O-methyl and R6' = O-methyl; or

[0623] R4' = O-methyl and R5' = -S(=O)2OH and R6' = H; or

[0624] R4' = O-methyl and R5' = -S(=O)2OH and R6' = sulfonyl; or

[0625] R4' = O-methyl and R5' = -S(=O)2OH and R6' = H; or

[0626] R4' = O-methyl and R5' = -S(=O)2OH and R6' = OH; or

[0627] R4' = O-methyl and R5' = -S(=O)2OH and R6' = methyl; or

[0628] R4' = O-methyl and R5' = -S(=O)2OH and R6' = O-methyl; or

[0629] R4' = O-methyl and R5' = -S(=O)2OH and R6' = -S(=O)2OH; or

[0630] R4' = O-methyl and R5' = -S(=O)2OH and R6' = sulfonyl; or

[0631] R4' = O-methyl and R5' = sulfonyl and R6' = H; or

[0632] R4' = O-methyl and R5' = sulfonyl and R6' = OH; or

[0633] R4' = O-methyl and R5' = sulfonyl and R6' = methyl; or

[0634] R4' = O-methyl and R5' = sulfonyl and R6' = O-methyl; or

[0635] R4' = O-methyl and R5' = sulfonyl and R6' = -S(=O)2OH; or

[0636] R4' = O-methyl and R5' = sulfonyl and R6' = sulfonyl; or

[0637] R4' = -S(=O)2OH and R5' = H and R6' = H; or

[0638] R4' = -S(=O)2OH and R5' = H and R6' = OH; or

[0639] R4' = -S(=O)2OH and R5' = H and R6' = methyl; or R4' = -S(=O)2OH and R5' = H and R6' = O-methyl; or

[0640] R4' = -S(=O)2OH and R5' = H and R6' = -S(=O)2OH; or

[0641] R4' = -S(=O)2OH and R5' = H and R6' = sulfonyl; or

[0642] R4' = -S(=O)2OH and R5' = OH and R6' = H; or

[0643] R4' = -S(=O)2OH and R5' = OH and R6' = OH; or

[0644] R4' = -S(=O)2OH and R5' = OH and R6' = methyl; or

[0645] R4' = -S(=O)2OH and R5' = OH and R6' = O-methyl; or

[0646] R4' = -S(=O)2OH and R5' = OH and R6' = -S(=O)2OH; or

[0647] R4' = -S(=O)2OH and R5' = OH and R6' = sulfonyl; or

[0648] R4' = -S(=O)2OH and R5' = methyl and R6' = H; or

[0649] R4' = -S(=O)2OH and R5' = methyl and R6' = OH; or

[0650] R4' = -S(=O)2OH and R5' = methyl and R6' = methyl; or

[0651] R4' = -S(=O)2OH and R5' = methyl and R6' = O-methyl; or

[0652] R4' = -S(=O)2OH and R5' = methyl and R6' = -S(=O)2OH; or

[0653] R4' = -S(=O)2OH and R5' = methyl and R6' = sulfonyl; or

[0654] R4' = -S(=O)2OH and R5' = O-methyl and R6' = H; or

[0655] R4' = -S(=O)2OH and R5' = O-methyl and R6' = OH; or

[0656] R4' = -S(=O)2OH and R5' = O-methyl and R6' = methyl; or

[0657] R4' = -S(=O)2OH and R5' = O-methyl and R6' = O-methyl; or

[0658] R4' = -S(=O)2OH and R5' = O-methyl and R6' = -S(=O)2OH; or

[0659] R4' = -S(=O)2OH and R5' = O-methyl and R6' = sulfonyl; or

[0660] R4' = -S(=O)2OH and R5' = -S(=O)2OH = and R6' = H; or

[0661] R4' = -S(=O)2OH and R5' = -S(=O)2OH and R6' = OH; or

[0662] R4' = -S(=O)2OH and R5' = -S(=O)2OH and R6' = methyl; or

[0663] R4' = -S(=O)2OH and R5' = -S(=O)2OH and R6' = O-methyl; or

[0664] R4' = -S(=O)2OH and R5' = sulfonyl and R6' = H; or

[0665] R4' = -S(=O)2OH and R5' = sulfonyl and R6' = OH; or

[0666] R4' = -S(=O)2OH and R5' = sulfonyl and R6' = methyl; or

[0667] R4' = -S(=O)2OH and R5' = sulfonyl and R6' = O-methyl; or

[0668] R4' = sulfonyl, R5' = H, and R6' = H; or

[0669] R4' = sulfonyl, R5' = H, and R6' = OH; or

[0670] R4' = sulfonyl, R5' = H, and R6' = methyl; or

[0671] R4' = sulfonyl, R5' = H, and R6' = O - methyl; or

[0672] R4' = sulfonyl, R5' = H, and R6' = -S(=O)2OH; or

[0673] R4' = sulfonyl, R5' = H, and R6' = sulfonyl; or

[0674] R4' = sulfonyl, R5' = OH, and R6' = H; or

[0675] R4' = sulfonyl, R5' = OH, and R6' = OH; or

[0676] R4' = sulfonyl, R5' = OH, and R6' = methyl; or

[0677] R4' = sulfonyl, R5' = OH, and R6' = O - methyl; or

[0678] R4' = sulfonyl, R5' = OH, and R6' = -S(=O)2OH; or

[0679] R4' = sulfonyl, R5' = OH, and R6' = sulfonyl; or

[0680] R4' = sulfonyl, R5' = methyl, and R6' = H; or

[0681] R4' = sulfonyl, R5' = methyl, and R6' = OH; or

[0682] R4' = sulfonyl, R5' = methyl, and R6' = methyl; or

[0683] R4' = sulfonyl, R5' = methyl, and R6' = O - methyl; or

[0684] R4' = sulfonyl, R5' = methyl, and R6' = -S(=O)2OH; or

[0685] R4' = sulfonyl, R5' = methyl, and R6' = sulfonyl; or

[0686] R4' = sulfonyl, R5' = O - methyl, and R6' = H; or

[0687] R4' = sulfonyl, R5' = O - methyl, and R6' = OH; or

[0688] R4' = sulfonyl, R5' = O - methyl, and R6' = methyl; or

[0689] R4' = sulfonyl, R5' = O - methyl, and R6' = O - methyl; or

[0690] R4' = sulfonyl, R5' = O - methyl, and R6' = -S(=O)2OH; or

[0691] R4' = sulfonyl, R5' = O - methyl, and R6' = sulfonyl; or

[0692] R4' = sulfonyl, R5' = -S(=O)2OH, and R6' = H; or

[0693] R4' = sulfonyl, R5' = -S(=O)2OH, and R6' = OH; or

[0694] R4' = sulfonyl, R5' = -S(=O)2OH, and R6' = methyl; or

[0695] R4' = sulfonyl, R5' = -S(=O)2OH, and R6' = O - methyl; or

[0696] R4' = sulfonyl, R5' = sulfonyl, and R6' = H; or

[0697] R4' = sulfonyl, R5' = sulfonyl, and R6' = OH; or

[0698] R4' = sulfonyl, R5' = sulfonyl, and R6' = methyl; or

[0699] R4' = sulfonyl, R5' = sulfonyl, and R6' = O - methyl; or

[0700] R4” = H, R5” = H, and R6” = H; or

[0701] R4” = H, R5” = H, and R6” = OH; or

[0702] R4” = H, R5” = H, and R6” = methyl; or

[0703] R4” = H, R5” = H, and R6” = O - methyl; or

[0704] R4” = H, R5” = H, and R6” = -S(=O)2OH; or

[0705] R4” = H and R5” = H and R6” = sulfonyl; or

[0706] R4” = H and R5” = OH and R6” = H; or

[0707] R4” = H and R5” = OH and R6” = OH; or

[0708] R4” = H and R5” = OH and R6” = methyl; or

[0709] R4” = H and R5” = OH and R6” = O - methyl; or

[0710] R4” = H and R5” = OH and R6” = -S(=O)2OH; or

[0711] R4” = H and R5” = OH and R6” = sulfonyl; or

[0712] R4” = H and R5” = methyl and R6” = H; or

[0713] R4” = H and R5” = methyl and R6” = OH; or

[0714] R4” = H and R5” = methyl and R6” = methyl; or

[0715] R4” = H and R5” = methyl and R6” = O - methyl; or

[0716] R4” = H and R5” = methyl and R6” = -S(=O)2OH; or

[0717] R4” = H and R5” = methyl and R6” = sulfonyl; or

[0718] R4” = H and R5” = O - methyl and R6” = H; or

[0719] R4” = H and R5” = O - methyl and R6” = OH; or

[0720] R4” = H and R5” = O - methyl and R6” = methyl; or

[0721] R4” = H and R5” = O - methyl and R6” = O - methyl; or

[0722] R4” = H and R5” = O - methyl and R6” = -S(=O)2OH; or

[0723] R4” = H and R5” = O - methyl and R6” = sulfonyl; or

[0724] R4” = H and R5” = -S(=O)2OH and R6” = H; or

[0725] R4” = H and R5” = -S(=O)2OH and R6” = OH; or

[0726] R4” = H and R5” = -S(=O)2OH and R6” = methyl; or

[0727] R4” = H and R5” = -S(=O)2OH and R6” = O-methyl; or

[0728] R4” = H and R5” = -S(=O)2OH and R6” = -S(=O)2OH; or

[0729] R4” = H and R5” = -S(=O)2OH and R6” = sulfonyl; or

[0730] R4” = H and R5” = sulfonyl and R6” = H; or

[0731] R4” = H and R5” = sulfonyl and R6” = OH; or

[0732] R4” = H and R5” = sulfonyl and R6” = methyl; or

[0733] R4” = H and R5” = sulfonyl and R6” = O-methyl; or

[0734] R4” = H and R5” = sulfonyl and R6” = -S(=O)2OH; or

[0735] R4” = H and R5” = sulfonyl and R6” = sulfonyl; or

[0736] R4” = OH and R5” = H and R6” = H; or

[0737] R4” = OH and R5” = H and R6” = OH; or

[0738] R4” = OH and R5” = H and R6” = methyl; or

[0739] R4” = OH and R5” = H and R6” = O-methyl; or

[0740] R4” = OH and R5” = H and R6” = -S(=O)2OH; or

[0741] R4” = OH and R5” = H and R6” = sulfonyl; or

[0742] R4” = OH and R5” = OH and R6” = H; or

[0743] R4” = OH and R5” = OH and R6” = OH; or

[0744] R4” = OH and R5” = OH and R6” = methyl; or

[0745] R4” = OH and R5” = OH and R6” = O - methyl; or

[0746] R4” = OH and R5” = OH and R6” = -S(=O)2OH; or

[0747] R4” = OH and R5” = OH and R6” = sulfonyl; or

[0748] R4” = OH and R5” = methyl and R6” = H; or

[0749] R4” = OH and R5” = methyl and R6” = OH; or

[0750] R4” = OH and R5” = methyl and R6” = methyl; or

[0751] R4” = OH and R5” = methyl and R6” = O - methyl; or

[0752] R4” = OH and R5” = methyl and R6” = -S(=O)2OH; or

[0753] R4” = OH and R5” = methyl and R6” = sulfonyl; or

[0754] R4” = OH and R5” = O - methyl and R6” = H; or

[0755] R4” = OH and R5” = O - methyl and R6” = OH; or

[0756] R4” = OH and R5” = O - methyl and R6” = methyl; or

[0757] R4” = OH and R5” = O - methyl and R6” = O - methyl; or

[0758] R4” = OH and R5” = O - methyl and R6” = -S(=O)2OH; or

[0759] R4” = OH and R5” = O - methyl and R6” = sulfonyl; or

[0760] R4” = OH and R5” = -S(=O)2OH and R6” = H; or

[0761] R4” = OH and R5” = -S(=O)2OH and R6” = OH; or

[0762] R4” = OH and R5” = -S(=O)2OH and R6” = methyl; or

[0763] R4” = OH and R5” = -S(=O)2OH and R6” = O-methyl; or

[0764] R4” = OH and R5” = -S(=O)2OH and R6” = -S(=O)2OH; or

[0765] R4” = OH and R5” = -S(=O)2OH and R6” = sulfonyl; or

[0766] R4” = OH and R5” = sulfonyl and R6” = H; or

[0767] R4” = OH and R5” = sulfonyl and R6” = OH; or

[0768] R4” = OH and R5” = sulfonyl and R6” = methyl; or

[0769] R4” = OH and R5” = sulfonyl and R6” = O-methyl; or

[0770] R4” = OH and R5” = sulfonyl and R6” = -S(=O)2OH; or

[0771] R4” = OH and R5” = sulfonyl and R6” = sulfonyl; or

[0772] R4” = methyl and R5” = H and R6” = H; or

[0773] R4” = methyl and R5” = H and R6” = OH; or

[0774] R4” = methyl and R5” = H and R6” = methyl; or

[0775] R4” = methyl and R5” = H and R6” = O-methyl; or

[0776] R4” = methyl and R5” = H and R6” = -S(=O)2OH; or

[0777] R4” = methyl and R5” = H and R6” = sulfonyl; or

[0778] R4” = methyl and R5” = OH and R6” = H; or

[0779] R4” = methyl and R5” = OH and R6” = OH; or

[0780] R4” = methyl and R5” = OH and R6” = methyl; or

[0781] R4” = methyl and R5” = OH and R6” = O - methyl; or

[0782] R4” = methyl and R5” = OH and R6” = -S(=O)2OH; or

[0783] R4” = methyl and R5” = OH and R6” = sulfonyl; or

[0784] R4” = methyl and R5” = methyl and R6” = H; or

[0785] R4” = methyl and R5” = methyl and R6” = OH; or

[0786] R4” = methyl and R5” = methyl and R6” = methyl; or

[0787] R4” = methyl and R5” = methyl and R6” = O - methyl; or

[0788] R4” = methyl and R5” = methyl and R6” = -S(=O)2OH; or

[0789] R4” = methyl and R5” = methyl and R6” = sulfonyl; or

[0790] R4” = methyl and R5” = O - methyl and R6” = H; or

[0791] R4” = methyl and R5” = O - methyl and R6” = OH; or

[0792] R4” = methyl and R5” = O - methyl and R6” = methyl; or

[0793] R4” = methyl and R5” = O - methyl and R6” = O - methyl; or

[0794] R4” = methyl and R5” = O - methyl and R6” = -S(=O)2OH; or

[0795] R4” = methyl and R5” = O - methyl and R6” = sulfonyl; or

[0796] R4” = methyl and R5” = -S(=O)2OH and R6” = H; or

[0797] R4” = methyl and R5” = -S(=O)2OH and R6” = OH; or

[0798] R4” = methyl and R5” = -S(=O)2OH and R6” = methyl; or

[0799] R4” = methyl and R5” = -S(=O)2OH and R6” = O-methyl; or

[0800] R4” = methyl and R5” = -S(=O)2OH and R6” = -S(=O)2OH; or

[0801] R4” = methyl and R5” = -S(=O)2OH and R6” = sulfonyl; or

[0802] R4” = methyl and R5” = sulfonyl and R6” = H; or

[0803] R4” = methyl and R5” = sulfonyl and R6” = OH; or

[0804] R4” = methyl and R5” = sulfonyl and R6” = methyl; or

[0805] R4” = methyl and R5” = sulfonyl and R6” = O-methyl; or

[0806] R4” = methyl and R5” = sulfonyl and R6” = -S(=O)2OH; or

[0807] R4” = methyl and R5” = sulfonyl and R6” = sulfonyl; or

[0808] R4” = O-methyl and R5” = H and R6” = H; or

[0809] R4” = O-methyl and R5” = H and R6” = OH; or

[0810] R4” = O-methyl and R5” = H and R6” = methyl; or

[0811] R4” = O-methyl and R5” = H and R6” = O-methyl; or

[0812] R4” = O-methyl and R5” = H and R6” = -S(=O)2OH; or

[0813] R4” = O-methyl and R5” = H and R6” = sulfonyl; or

[0814] R4” = O-methyl and R5” = OH and R6” = H; or

[0815] R4” = O-methyl and R5” = OH and R6” = OH; or

[0816] R4” = O-methyl, R5” = OH, and R6” = methyl; or

[0817] R4” = O-methyl, R5” = OH, and R6” = O-methyl; or

[0818] R4” = O-methyl, R5” = OH, and R6” = -S(=O)2OH; or

[0819] R4” = O-methyl, R5” = OH, and R6” = sulfonyl; or

[0820] R4” = O-methyl, R5” = methyl, and R6” = H; or

[0821] R4” = O-methyl, R5” = methyl, and R6” = OH; or

[0822] R4” = O-methyl, R5” = methyl, and R6” = methyl; or

[0823] R4” = O-methyl, R5” = methyl, and R6” = O-methyl; or

[0824] R4” = O-methyl, R5” = methyl, and R6” = -S(=O)2OH; or

[0825] R4” = O-methyl, R5” = methyl, and R6” = sulfonyl; or

[0826] R4” = O-methyl, R5” = O-methyl, and R6” = H; or

[0827] R4” = O-methyl, R5” = O-methyl, and R6” = OH; or

[0828] R4” = O-methyl, R5” = O-methyl, and R6” = methyl; or

[0829] R4” = O-methyl, R5” = O-methyl, and R6” = O-methyl; or

[0830] R4” = O-methyl, R5” = O-methyl, and R6” = -S(=O)2OH; or

[0831] R4” = O-methyl, R5” = O-methyl, and R6” = sulfonyl; or

[0832] R4” = O-methyl, R5” = -S(=O)2OH, and R6” = H; or

[0833] R4” = O-methyl, R5” = -S(=O)2OH, and R6” = OH; or

[0834] R4” = O-methyl and R5” = -S(=O)2OH and R6” = methyl; or

[0835] R4” = O-methyl and R5” = -S(=O)2OH and R6” = O-methyl; or

[0836] R4” = O-methyl and R5” = -S(=O)2OH and R6” = -S(=O)2OH; or

[0837] R4” = O-methyl and R5” = -S(=O)2OH and R6” = sulfonyl; or

[0838] R4” = O-methyl and R5” = sulfonyl and R6” = H; or

[0839] R4” = O-methyl and R5” = sulfonyl and R6” = OH; or

[0840] R4” = O-methyl and R5” = sulfonyl and R6” = methyl; or

[0841] R4” = O-methyl and R5” = sulfonyl and R6” = O-methyl; or

[0842] R4” = O-methyl and R5” = sulfonyl and R6” = -S(=O)2OH; or

[0843] R4” = O-methyl and R5” = sulfonyl and R6” = sulfonyl; or

[0844] R4” = -S(=O)2OH and R5” = H and R6” = H; or

[0845] R4” = -S(=O)2OH and R5” = H and R6” = OH; or

[0846] R4” = -S(=O)2OH and R5” = H and R6” = methyl; or

[0847] R4” = -S(=O)2OH and R5” = H and R6” = O-methyl; or

[0848] R4” = -S(=O)2OH and R5” = H and R6” = -S(=O)2OH; or

[0849] R4” = -S(=O)2OH and R5” = H and R6” = sulfonyl; or

[0850] R4” = -S(=O)2OH and R5” = OH and R6” = H; or

[0851] R4” = -S(=O)2OH and R5” = OH and R6” = OH; or

[0852] R4” = -S(=O)2OH and R5” = OH and R6” = methyl; or

[0853] R4” = -S(=O)2OH and R5” = OH and R6” = O-methyl; or

[0854] R4” = -S(=O)2OH and R5” = OH and R6” = -S(=O)2OH; or

[0855] R4” = -S(=O)2OH and R5” = OH and R6” = sulfonyl; or

[0856] R4” = -S(=O)2OH and R5” = methyl and R6” = H; or

[0857] R4” = -S(=O)2OH and R5” = methyl and R6” = OH; or

[0858] R4” = -S(=O)2OH and R5” = methyl and R6” = methyl; or

[0859] R4” = -S(=O)2OH and R5” = methyl and R6” = O-methyl; or

[0860] R4” = -S(=O)2OH and R5” = methyl and R6” = -S(=O)2OH; or

[0861] R4” = -S(=O)2OH and R5” = methyl and R6” = sulfonyl; or

[0862] R4” = -S(=O)2OH and R5” = O-methyl and R6” = H; or

[0863] R4” = -S(=O)2OH and R5” = O-methyl and R6” = OH; or

[0864] R4” = -S(=O)2OH and R5” = O-methyl and R6” = methyl; or

[0865] R4” = -S(=O)2OH and R5” = O-methyl and R6” = O-methyl; or

[0866] R4” = -S(=O)2OH and R5” = O-methyl and R6” = -S(=O)2OH; or

[0867] R4” = -S(=O)2OH and R5” = O-methyl and R6” = sulfonyl; or

[0868] R4” = -S(=O)2OH and R5” = -S(=O)2OH = and R6” = H; or

[0869] R4” = -S(=O)2OH and R5” = -S(=O)2OH and R6” = OH; or

[0870] R4” = -S(=O)2OH and R5” = -S(=O)2OH and R6” = methyl; or

[0871] R4” = -S(=O)2OH and R5” = -S(=O)2OH and R6” = O-methyl; or

[0872] R4” = -S(=O)2OH and R5” = sulfonyl = and R6” = H; or

[0873] R4” = -S(=O)2OH and R5” = sulfonyl and R6” = OH; or

[0874] R4” = -S(=O)2OH and R5” = sulfonyl and R6” = methyl; or

[0875] R4” = -S(=O)2OH and R5” = sulfonyl and R6” = O-methyl; or

[0876] R4” = sulfonyl and R5” = H and R6” = H; or

[0877] R4” = sulfonyl and R5” = H and R6” = OH; or

[0878] R4” = sulfonyl and R5” = H and R6” = methyl; or

[0879] R4” = -sulfonyl and R5” = H and R6” = O-methyl; or

[0880] R4” = sulfonyl and R5” = H and R6” = -S(=O)2OH; or

[0881] R4” = sulfonyl and R5” = H and R6” = sulfonyl; or

[0882] R4” = sulfonyl and R5” = OH and R6” = H; or

[0883] R4” = sulfonyl and R5” = OH and R6” = OH; or

[0884] R4” = sulfonyl and R5” = OH and R6” = methyl; or

[0885] R4” = sulfonyl and R5” = OH and R6” = O - methyl; or

[0886] R4” = sulfonyl and R5” = OH and R6” = -S(=O)2OH; or

[0887] R4” = sulfonyl and R5” = OH and R6” = sulfonyl; or

[0888] R4” = sulfonyl and R5” = methyl and R6” = H; or

[0889] R4” = sulfonyl and R5” = methyl and R6” = OH; or

[0890] R4” = sulfonyl and R5” = methyl and R6” = methyl; or

[0891] R4” = sulfonyl and R5” = methyl and R6” = O - methyl; or

[0892] R4” = sulfonyl and R5” = methyl and R6” = -S(=O)2OH; or

[0893] R4” = sulfonyl and R5” = methyl and R6” = sulfonyl; or

[0894] R4” = sulfonyl and R5” = O - methyl and R6” = H; or

[0895] R4” = sulfonyl and R5” = O - methyl and R6” = OH; or

[0896] R4” = sulfonyl and R5” = O - methyl and R6” = methyl; or

[0897] R4” = sulfonyl and R5” = O - methyl and R6” = O - methyl; or

[0898] R4” = sulfonyl and R5” = O - methyl and R6” = -S(=O)2OH; or

[0899] R4” = sulfonyl and R5” = O - methyl and R6” = sulfonyl; or

[0900] R4” = sulfonyl and R5” = -S(=O)2OH and R6” = H; or

[0901] R4” = sulfonyl and R5” = -S(=O)2OH and R6” = OH; or

[0902] R4” = sulfonyl and R5” = -S(=O)2OH and R6” = methyl; or

[0903] R4” = sulfonyl and R5” = -S(=O)2OH and R6” = O-methyl; or

[0904] R4” = sulfonyl and R5” = sulfonyl and R6” = H; or

[0905] R4” = sulfonyl and R5” = sulfonyl and R6” = OH; or

[0906] R4” = sulfonyl and R5” = sulfonyl and R6” = methyl; or

[0907] R4” = sulfonyl and R5” = sulfonyl and R6” = O-methyl.

[0908] In the general formulas (V), (VI), (VII), (VIII), (IX) and (X) and their variants, the substituted benzene ring bonded to the imino functional group is preferably selected from the group consisting of:

[0909]

[0910] wherein the dashed line represents the binding site to the cyclohexeneimine ring.

[0911] In a still more preferred variant according to the first aspect of the present invention, in the general formulas (V), (VII), (VIII) and their variants, the substituents R4', R5' and R6', which may be the same or different, are independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl or tert-butyl, alkoxy, preferably O-methyl, O-ethyl or O-butyl, -S(=O)2OH and sulfonyl; provided that if the substituted benzene ring is monosubstituted, the substituent is in the ortho or meta position to the imino functional group of the general formulas (V), (VI) and (VIII), rather than in the para position to the imino functional group.

[0912] In a still more preferred variant according to the first aspect of the present invention, in the general formulas (VI), (IX), (X) and their variants, the substituents R4”, R5” and R6”, which may be the same or different, are independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl or tert-butyl, alkoxy, preferably O-methyl, O-ethyl or O-butyl, -S(=O)2OH and sulfonyl; provided that if the substituted benzene ring is monosubstituted, the substituent is in the ortho or meta position to the imino functional group of the general formulas (VI), (IX), (X), rather than in the para position to the imino functional group.

[0913] According to a first aspect of the present invention, still more preferably, a sunscreen product, a cosmetic product, a pharmaceutical preparation or a household care product comprises at least one mycosporine-like amino acid compound selected from the group consisting of:

[0914] Table 3 :

[0915]

[0916]

[0917]

[0918]

[0919]

[0920] or a tautomer or stereoisomer or salt of the above compounds or any mixture of the above compounds.

[0921] Among the above-specified mycosporine-like amino acid compounds, compounds MAA-1 and MAA-13 are particularly preferred because they have a significant effect of improving water resistance. Most preferred are the acid compounds MAA-20, MAA-21, MAA-22, MAA-23, MAA-24, MAA-24, MAA-26, MAA-27, MAA-28, MAA-29, MAA-30, MAA-31 and the amide compounds MAA-32, MAA-33, MAA-34, MAA-35, MAA-36, MAA-37, MAA-38 and MAA-39. The said compounds having an acid functional group or an amide functional group are photo-stable and temperature-stable and exhibit stability in a pH solution or in an oil-in-water emulsion and do not degrade.

[0922] In particular, mycosporine-like amino acid compounds having an acid functional group have better pH stability in a wider pH range compared to their corresponding hydrolyzable ester compounds and are thus unstable in an alkaline solution with a pH above 9.

[0923] Due to their better solubility in water, the said mycosporine-like amino acid compounds can be incorporated into the aqueous phase of the emulsion at a higher concentration, resulting in an enhanced effect of the film-forming agent and thus having an improved sun protection efficacy in a sunscreen product, a cosmetic product, a pharmaceutical preparation or a household care product compared to their corresponding ester compounds.

[0924] According to a first aspect of the present invention, still more preferably, a sunscreen product, a cosmetic product, a pharmaceutical preparation or a household care product comprises at least one mycosporine-like amino acid compound selected from the group consisting of:

[0925] MAA-A:

[0926]

[0927] MAA-B:

[0928]

[0929] MAA-C:

[0930]

[0931] or a tautomer or stereoisomer or salt of the above compounds or any mixture of the above compounds, wherein the alkyl group is preferably methyl or ethyl or propyl or isopropyl or butyl or isobutyl or tert-butyl, most preferably methyl.

[0932] The mycosporine-like amino acid compound according to the present invention and defined herein is used as a single substance or in admixture with one, two or more different mycosporine-like amino acid compounds as defined herein.

[0933] Particularly preferred is a mixture of two mycosporine-like amino acid compounds according to the present invention and defined herein. As demonstrated in the following examples, this mixture exhibits a particularly enhanced strengthening effect.

[0934] The sunscreen product, cosmetic or pharmaceutical composition or household care product according to the first aspect of the present invention is further characterized in that the sunscreen product, cosmetic or pharmaceutical composition or household care product comprises one or more of the following mycosporine-like amino acid compounds:

[0935] Compound 1:

[0936]

[0937] Compound 2:

[0938]

[0939] Compound 3:

[0940]

[0941] Compound 4:

[0942]

[0943] Compound 5:

[0944]

[0945] Compound 6:

[0946]

[0947] Compound 7:

[0948]

[0949] Compound 8:

[0950]

[0951] The various mycosporine - like amino acid compounds (b) as described herein contain one or more chiral centers and can thus exist as racemic mixtures of enantiomers, mixtures of diastereomers, or in the form of enantiomers or optically pure compounds. It should also be noted that the compounds of the present invention include E and Z isomers or mixtures thereof, as well as cis and trans isomers or mixtures thereof.

[0952] Accordingly, the chemical structures of the general formulas (V) to (X) and their variants and compounds explicitly disclosed herein include all possible enantiomers and diastereomers or stereoisomers.

[0953] In certain embodiments, the mycosporine - like amino acid compounds (b) of the present invention are isolated as E or Z isomers. In other embodiments, the compounds of the present invention are mixtures of E and Z isomers.

[0954] Alternatively, stereoisomerically pure compounds are used in the sunscreen products, cosmetic or pharmaceutical formulations, or household care products according to the present invention. As used herein and unless otherwise specified, the term "stereoisomerically pure" means that one stereoisomer of a compound is substantially free of other stereoisomers of the compound, or that one geometric isomer (e.g., about one double bond) is substantially free of other geometric isomers. For example, a stereoisomerically pure compound of the present invention having one chiral center will be substantially free of the opposite enantiomer of the compound. A stereoisomerically pure compound or composition of the present invention having two chiral centers will be substantially free of other diastereomers of the compound. A stereoisomerically pure compound or composition of the present invention having a double bond capable of E / Z isomerization will be substantially free of one of the E / Z isomers.

[0955] Typical stereoisomerically pure compounds include greater than about 80% by weight of one stereoisomer or E / Z isomer of the compound and less than about 20% by weight of other stereoisomers or E / Z isomers, more preferably greater than about 90% by weight of one stereoisomer or E / Z isomer of the compound and less than about 10% by weight of other stereoisomers or E / Z isomers, even more preferably greater than about 95% by weight of one stereoisomer or E / Z isomer of the compound and less than about 5% by weight of other stereoisomers or E / Z isomers, and most preferably greater than about 97% by weight of one stereoisomer or E / Z isomer of the compound and less than about 3% by weight of other stereoisomers or E / Z isomers.

[0956] As used herein and unless otherwise indicated, the term "stereoisomer-enriched" means a compound or composition thereof of the present invention, which compound or composition thereof contains greater than about 60% by weight of one stereoisomer or E / Z isomer of the compound of the present invention, preferably greater than about 70% by weight, more preferably greater than about 80% by weight of one stereoisomer or E / Z isomer of the compound of the present invention.

[0957] Accordingly, it should be noted that unless otherwise indicated, the term "mycosporine-like amino acid compound" according to general formulas (V) to (X) and their variants, as well as the individual mycosporine-like amino acid compounds specified herein, will be interpreted to cover racemic mixtures of enantiomers, mixtures of diastereomers, or enantiomeric or optically pure compounds.

[0958] Due to their amino-cyclohexene-imine structure and their ability for electron delocalization, the compounds according to general formulas (I) to (X) are in equilibrium with their tautomeric structures, in which the hydrogen of the amino group exchanges positions with the double bond of the cyclohexene ring.

[0959] Tautomerism is defined as each of two or more isomers of a compound, which two or more isomers coexist in an equilibrium state and are readily interchangeable by the migration of an atom or group within the molecule. Over time, a tautomerically pure system or an enriched system will readily interconvert to an equilibrium state.

[0960] The tautomer of general formula (V) is represented by general formula (V-τ):

[0961]

[0962] The tautomer of general formula (VI) is represented by general formula (VI-τ):

[0963]

[0964] The above-described tautomerization and redeposition principles, explained based on the mycosporine-like amino acid compounds according to general formulas (V) and (VI), apply equally to any mycosporine-like amino acid compound defined by general formulas (VII), (VIII), (IX), (X) and their variants, or to any individual mycosporine-like amino acid compound specified herein.

[0965] Accordingly, throughout the following and the entire specification, reference to a mycosporine-like amino acid compound represented by any one of general formulas (V) to (X) and their variants, or to an individual mycosporine-like amino acid compound specified herein, also encompasses its tautomeric isomers.

[0966] According to a first aspect of the invention, the mycosporine-like amino acid compounds according to general formulas (V) to (X) and their variants, as well as the individual mycosporine-like amino acid compounds specified herein, are used in neutral (i.e., uncharged form), or in the form of their salts, such as acid addition salts with inorganic or organic acids.

[0967] The term "salt" in the context of the present invention refers to salts of compounds that have the desired effects or pharmacological activities of the parent compound. Such salts include:

[0968] (1) acid addition salts formed with inorganic acids or with organic acids, preferably monovalent or polyvalent carboxylic acids; or

[0969] (2) salts formed when the acidic protons present in the starting compound are replaced by metal ions (e.g., alkali metal ions, alkaline earth ions or aluminum ions); or salts formed by coordination with organic bases.

[0970] Among these salts, acid addition salts are also particularly preferred because the mycosporine-like amino acid compounds according to general formulas (V) to (X) and their variants, or the mycosporine-like amino acid compounds specified herein, include protonatable N atoms.

[0971] The inorganic acids that form acid addition salts with the mycosporine-like amino acid compounds are preferably selected from the group consisting of hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid, etc. Particularly preferred are hydrochloride or sulfate or phosphate.

[0972] Even more preferably, it is an acid addition salt with an organic monocarboxylic acid or polycarboxylic acid. Further preferably, it is an acid addition salt with an organic monocarboxylic acid or polycarboxylic acid, wherein the carboxylic acid is selected from the group consisting of saturated or mono-unsaturated or poly-unsaturated C1 to C30 monocarboxylic acids, saturated or mono-unsaturated or poly-unsaturated C3 to 10 dicarboxylic acids or tricarboxylic acids. The carboxylic acid can be mono-substituted or multi-substituted by hydroxyl groups, preferably α-hydroxy carboxylic acids, wherein the hydroxyl group is located on the carbon atom adjacent to the carboxyl group. Many representatives occur naturally in the form of so-called fruit acids. Preferred α-hydroxy carboxylic acids are malic acid, citric acid, 2-hydroxy-4-methylthiobutyric acid, glycolic acid, isocitric acid, mandelic acid, lactic acid, tartronic acid or tartaric acid.

[0973] The organic acids that form acid addition salts with mycosporine-like amino acid compounds are preferably selected from the group consisting of: amino acids, acetic acid, trifluoroacetic acid, propionic acid, hexanoic acid, cyclopentanepropionic acid, glycolic acid, pyruvic acid, lactic acid, malonic acid, oxalic acid, succinic acid, malic acid, maleic acid, fumaric acid, tartaric acid, citric acid, benzoic acid, 3-(4-hydroxybenzoyl)benzoic acid, cinnamic acid, mandelic acid, methanesulfonic acid, ethanesulfonic acid, 1,2-ethanedisulfonic acid, 2-hydroxyethanesulfonic acid, benzenesulfonic acid, 4-chlorobenzenesulfonic acid, 2-naphthalenesulfonic acid, 4-toluenesulfonic acid, camphorsulfonic acid, 4-methylbicyclo[2.2.2]-oct-2-ene-1-carboxylic acid, glucoheptonic acid, 3-phenylpropionic acid, trimethylacetic acid, tert-butylacetic acid, dodecylsulfuric acid, gluconic acid, glutamic acid, hydroxynaphthoic acid, salicylic acid, stearic acid, mucic acid, 4-hydroxybutyric acid, etc.

[0974] Suitable anionic counterions are especially chloride, bromide, hydrogen sulfate, sulfate, dihydrogen phosphate, hydrogen phosphate, phosphate, nitrate, hydrogen carbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate and the anions of C1 to C4-alkanoic acids, preferably formate, acetate, trifluoroacetate, propionate and butyrate, in addition lactate, gluconate, and the anions of polyacids such as succinate, oxalate, maleate, fumarate, malate, tartrate and citrate, in addition sulfonate anions such as benzenesulfonate (benzenesulfonate), toluenesulfonate (p-toluenesulfonate), naphthalenesulfonate (naphthalene-2-sulfonate), methanesulfonate (methanesulfonate), ethanesulfonate (ethanesulfonate) and ethanedisulfonate. They can be formed by reacting the compounds with basic functional groups according to the invention with the acids of the corresponding anions. The preferred salts of the compounds of formulas (I) to (III) and the individual mycosporine-like amino acid compounds specified herein are chloride salts.

[0975] The metal ions for salt formation that replace the acidic protons present in the starting compound are selected from the group consisting of: alkali metal ions (preferably Na+, K+ or Li+), alkaline earth metal ions (preferably Ca++, Mg++, Al+++ or NH4+).

[0976] The coordinating organic bases for salt formation are selected from the group consisting of: ethanolamine, diethanolamine, triethanolamine, N-methylglucosamine, triethylamine, etc.

[0977] In the following description and claims, unless otherwise specified, the term "mycosporine-like amino acid compound" includes the neutral, uncharged form of the compound / molecule, as well as the salt form of the compound.

[0978] The salt form of the mycosporine-like amino acid compound results in a lower logP OW , and thus makes the compound more hydrophilic, which leads to better water solubility. In particular, the cationic salts of mycosporine-like amino acid compounds support the emulsification process in emulsions due to their surface activity (i.e., co-emulsifying properties). Additionally, the cationic salt form of the mycosporine compound exhibits excellent affinity behavior on the skin and hair: most conditioning active substances are cationic; the conditioning effect results in a softer skin feel, which makes the final product more acceptable to consumers. Additionally, the mycosporine-like amino acid compound in cationic salt form exhibits antimicrobial activity.

[0979] The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention optionally comprises at least one film-forming agent (c). Optionally means that the film-forming agent is not mandatory in the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention, but can be advantageously incorporated. Film-forming agents are well known in the art as reagents for improving the water resistance of sunscreen products.

[0980] Improving water resistance is the process of making an object or structure more waterproof, so that it is relatively unaffected by water or resists the entry of water under specified conditions.

[0981] Film-forming agents are hydrophobic materials that impart water resistance and film-forming properties to sunscreen products, cosmetics or pharmaceutical preparations or household care products. Typical suitable film-forming agents include copolymers derived from the polymerization of octadecene-1 and maleic anhydride. A preferred film-forming agent is polyanhydride resin. Another preferred film-forming agent is a copolymer of vinylpyrrolidone and eicosenyl monomer.

[0982] Standard film-forming agents are chitosan, microcrystalline chitosan, quaternized chitosan, polyvinylpyrrolidone, vinylpyrrolidone / vinyl acetate copolymer, polymers of the acrylic acid series, quaternary cellulose derivatives, collagen, hyaluronic acid and their salts and similar compounds. Preferably, the film-forming agent is selected from the group consisting of: chitosan, microcrystalline chitosan, quaternized chitosan, polyvinylpyrrolidone, vinylpyrrolidone / vinyl acetate copolymer, polymers of the acrylic acid series, quaternary cellulose derivatives, collagen, hyaluronic acid and their salts and similar compounds. Preferred film-forming substances for improving the water resistance of the composition are selected from the group consisting of: polyamide-8 (such as Oleocraft LP 20PA (MV)), polyamide-3 (such as Oleocraft MP 32PA (MV)), trimethylpentanediol / adipic acid / glycerol crosslinked polymer (such as wet film), octyldodecyl citrate crosslinked polymer (such as CosmoSurf CE 100), polyglyceryl-3 methylglucoside distearate (such as TegoCare 450), C28-52 olefin / undecenoic acid copolymer (such as Performa V6112), hydrolyzed jojoba ester, jojoba ester, aqueous agent (such as Floraester jojoba K100), cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545), acrylate / behenyl polyether-25 methacrylate copolymer (such as Volarest), styrene / acrylate copolymer (such as Dermacryl E polymer), polyurethane (such as Baycusan C1001), polyurethane-2 and polymethyl methacrylate (such as Hybridur 875 polymer), acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer), beeswax (white beeswax) (and) sodium stearoyl lactate (such as SymEffekt Sun), hydrogenated palm oil, sugar cane extract (SymEffect TM UV), microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer), gum arabic and xanthan gum (such as SOLAGUM TM AX), microcrystalline cellulose (and) cellulose gum (such as Natpure Cellgum enhanced version), sodium stearoyl glutamate (such as HS-11P), hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT), glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT), galactoarabinan (such as A 200), C26 - 28 alkyl dimethicone (such as Wacker CDM3526VP), octanoyl methyl siloxane (such as Silsoft 034), stearyl dimethicone (and) octadecene (such as Dowsil 2503 cosmetic wax), VP / hexadecene copolymer (such as Antaron TM V 216), triacontanyl PVP (such as Antaron TM WP - 660), caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB), poly C10 - 30 alkyl acrylate (such as Tego SP 13 Sun Up), microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer) and any mixture thereof.

[0983] According to the present invention, these film - forming agents are preferably selected from the group consisting of: polyamide - 8 (such as Oleocraft LP 20PA (MV)), polyamide - 3 (such as Oleocraft MP 32PA (MV)), trimethylolpropane / adipic acid / glycerol cross - linked polymer (such as wet film), octyldodecyl citrate cross - linked polymer (such as CosmoSurf CE 100), polyglyceryl - 3 methyl glucoside distearate (such as TegoCare 450), C28 - 52 olefin / undecenoic acid copolymer (such as Performa V6112), hydrolyzed jojoba ester, jojoba ester, aqueous agent (such as Floraester jojoba K100), cyclopentasiloxane acrylate / dimethyl polysiloxane copolymer (such as KP545), acrylate / behenyl polyether - 25 methacrylate copolymer (such as Volarest), styrene / acrylate copolymer (such as Dermacryl E polymer), polyurethane (such as Baycusan C1001), polyurethane - 2 and polymethyl methacrylate (such as Hybridur 875 polymer), acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer), beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffektSun), amylopectin, xanthan gum, hydrogenated palm oil, sugarcane extract (SymEffect TM UV), microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer), gum arabic and xanthan gum (such as SOLAGUM TMAX), microcrystalline cellulose (and) cellulose gum (such as Natpure Cellgum Plus), sodium stearoyl glutamate (such as HS-11P), hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT), glyceryl hydrogenated rosinate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT), galactomannan (such as A 200), C26-28 alkyl dimethicone (such as Wacker CDM 3526VP), octanoyl methylsiloxane (such as Silsoft 034), stearyl dimethicone (and) octadecene (such as Dowsil 2503 cosmetic wax), VP / hexadecene copolymer (such as Antaron TM V 216), tricontanyl PVP (such as Antaron TM WP-660), caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB), poly C10-30 alkyl acrylate (such as Tego SP 13 SunUp), microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer) and any mixtures thereof.

[0984] More preferably, these film formers are preferably selected from the group consisting of: trimethylpentanediol / adipic acid / glycerol crosslinked polymer (such as wet film), octyldodecyl citrate crosslinked polymer (such as CosmoSurf CE 100), polyglyceryl-3 methylglucose distearate (such as TegoCare 450), C28-52 olefin / undecenoic acid copolymer (such as Performa V6112), hydrolyzed jojoba ester, jojoba ester, aqueous agent (such as Floraester jojoba K100), cyclopentasiloxane acrylate / dimethylpolysiloxane copolymer (such as KP545), styrene / acrylic acid copolymer (such as DermacrylE polymer), acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer), beeswax (white beeswax) (and) sodium stearoyl lactate (such as SymEffect TM Sun), amylopectin, xanthan gum, hydrogenated palm oil, sugarcane extract (SymEffect TM UV), microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TMSTART polymer), gum arabic and xanthan gum (such as SOLAGUM TM AX), microcrystalline cellulose (and) cellulose gum (such as Natpure Cellgum Plus), sodium stearoyl glutamate (such as HS-11P), hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT), glyceryl hydrogenated rosinate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT), galactoarabinan (such as A 200), C26-28 alkyl dimethicone (such as Wacker CDM3526VP), octanoyl methyl siloxane (such as Silsoft 034), stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax), VP / hexadecene copolymer (such as Antaron TM V 216), triacontanyl PVP (such as Antaron TM WP-660), caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB), poly C10-30 alkyl acrylate (such as Tego SP 13 Sun Up), microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer) and any mixture thereof.

[0985] More preferably, these film-forming agents are preferably selected from the group consisting of: hydrolyzed jojoba esters, jojoba esters, aqueous agents (such as Floraester jojoba K100), cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545), styrene / acrylic acid copolymer (such as Dermacryl E polymer), acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer), beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffect Sun), amylopectin, xanthan gum, hydrogenated palm oil, sugarcane extract (SymEffect TM UV), microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer), microcrystalline cellulose (and) cellulose gum (such as Natpure Cellgum Plus), hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT), glyceryl hydrogenated rosinate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063 - CCT), galactoarabinan (such as A 200), C26 - 28 alkyldimethyl polysiloxane (such as Wacker CDM 3526VP), stearyl dimethicone (and) octadecene (such as Dowsil 2503 cosmetic wax), VP / hexadecene copolymer (such as Antaron TM V 216), tricontanyl PVP (such as Antaron TM WP - 660), caprylyl glycerol / sebacate copolymer (such as LexFilm TM Sun Natural MB), poly C10 - 30 alkyl acrylate (such as Tego SP 13 Sun Up), microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer) and any mixtures thereof.

[0986] The aforementioned film - forming agents are used as a single component or preferably in admixture with two or more of the film - forming agents as specified above in sunscreen, cosmetic or pharmaceutical formulations or household care products.

[0987] The film - forming agent (c) is used in an amount effective to retain the final formulation on the skin after exposure to circulating water for at least 40 minutes to 80 minutes.

[0988] By adding the mycosporine - like amino acid compound (b) as defined herein to a sunscreen product, cosmetic or pharmaceutical formulation or household care product according to the invention, the adhesion of the film - forming agent (c) to the skin or surface can be significantly improved. Preferably, the combination of the mycosporine - like amino acid compound (b) and the film - forming agent (c) results in a synergistic adhesion effect of the sunscreen product, cosmetic or pharmaceutical formulation or household care product on the skin or surface to which the formulation is applied. The improvement in the adhesion of the film - forming agent in turn leads to an improvement in water resistance, and thus, provides excellent UV protection even after bathing compared to products or formulations without the specified mycosporine - like amino acid compound.

[0989] In a particularly advantageous variant, the sunscreen product, cosmetic or pharmaceutical formulation or household care product according to the first aspect of the invention thus comprises one combination from the following combinations of components (b) and (c):

[0990] ■At least one MAA compound according to general formula (V) as defined herein plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffect Sun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffect TM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM 3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacate copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as Tego SP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[0991] ■At least one MAA compound according to general formula (VI) as defined herein plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters, aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffect Sun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffect TM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM 3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as Tego SP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[0992] ■At least one MAA compound according to general formula (VII) as defined herein, plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffect Sun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffect TM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM 3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or trityl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacate copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as Tego SP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[0993] ■At least one compound according to general formula (VIII) as defined herein plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffect Sun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffect TM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM 3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as Tego SP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer).

[0994] A more preferred combination of components (b) and (c) in the sunscreen product or cosmetic or pharmaceutical preparation according to the first aspect of the present invention is:

[0995] ■ MAA-1 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffect TM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM 3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as Tego SP13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[0996] ■ MAA-2 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or triacontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[0997] ■ MAA-3 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[0998] ■ MAA-4 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas ferment extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or trityl PVP (such as Antaron TM WP-660) and / or octanoyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[0999] ■ MAA-5 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster); or

[1000] ■ MAA-6 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or triacontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1001] ■ MAA-7 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or triacontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1002] ■ MAA-8 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or trityl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacate copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1003] ■ MAA-9 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Enhanced) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1004] ■MAA-11 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1005] ■ MAA-12 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or triacontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1006] ■ MAA-13 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Enhanced) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1007] ■ MAA-14 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas ferment extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1008] ■ MAA-16 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacate copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1009] ■ MAA-17 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster); or

[1010] ■ MAA-20 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1011] ■MAA-21 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas ferment extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster); or

[1012] ■ MAA-22 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1013] ■ MAA-23 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas ferment extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Enhanced) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1014] ■ MAA-24 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Enhanced) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster); or

[1015] ■ MAA-25 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster); or

[1016] ■ MAA-26 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1017] ■ MAA-27 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster); or

[1018] ■ MAA-28 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1019] ■ MAA-29 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1020] ■MAA-30 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or trityl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1021] ■ MAA-31 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster); or

[1022] ■ MAA-32 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1023] ■ MAA-33 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or triacontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1024] ■ MAA-34 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum enhanced version) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or triacontanyl PVP (such as Antaron TM WP-660) and / or octanoyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1025] ■ MAA-35 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or triacontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1026] ■MAA-36 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactomannan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1027] ■ MAA-37 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1028] ■MAA-38 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugarcane extract (SymEffectTM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as Natpure Cellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glyceryl hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerin / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as TegoSP 13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer); or

[1029] ■ MAA-39 plus at least one film-forming agent: hydrolyzed jojoba esters and / or jojoba esters and / or aqueous agents (such as Floraester Jojoba K100) and / or cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545) and / or styrene / acrylate copolymer (such as Dermacryl E polymer) and / or acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer) and / or beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffectSun) and / or amylose and / or xanthan gum and / or hydrogenated palm oil, sugar cane extract (SymEffect TM UV) and / or microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer) and / or microcrystalline cellulose (and) cellulose gum (such as NatpureCellgum Plus) and / or hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT) and / or glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT) and / or galactoarabinan (such as A 200) and / or C26-28 alkyl dimethicone (such as Wacker CDM 3526VP) and / or stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax) and / or VP / hexadecene copolymer (such as Antaron TM V 216) and / or tricontanyl PVP (such as Antaron TM WP-660) and / or caprylyl glycerol / sebacic acid copolymer (such as LexFilm TM Sun Natural MB) and / or poly C10-30 alkyl acrylate (such as Tego SP13 Sun Up) and / or microcrystalline cellulose (such as Sunspheres TM BIO SPF Booster).

[1030] Combinations of mycosporine - like amino acid compounds such as MAA - 1, MAA - 2, MAA - 3, MAA - 4, MAA - 5, MAA - 6, MAA - 7, MAA - 8, MAA - 9, MAA - 11, MAA - 13, MAA - 14, MAA - 16, MAA - 17, MAA - 20, MAA - 21, MAA - 22, MAA - 23, MAA - 24, MAA - 25, MAA - 26, MAA - 27, MAA - 28, MAA - 29, MAA - 30, MAA - 31, MAA - 32, MAA - 33, MAA - 34, MAA - 35, MAA - 36, MAA - 37, MAA - 38, MAA - 39 and any film - forming agent in a film - forming agent can show a synergistic improvement effect in water resistance. This sticky effect can be particularly observed when the mycosporine - like amino acid compound is in its salt form, i.e., its cationic form. For MAA - 1 and MAA - 13, a beneficial improvement effect in stickiness can be preferably obtained. The combination of the film - forming agent and the mycosporine - like amino acid compound shows a unique adhesion on the skin or surface of a sunscreen product, a cosmetic product or a pharmaceutical preparation or a household care product, thus leading to an improvement in water resistance.

[1031] When combined with any film - forming agent, the adhesion improvement effect is particularly significant for the mycosporine - like amino acid compounds MAA - 20 to MAA - 39.

[1032] When combined with any film - forming agent, the mycosporine - like amino acid compounds MAA - A, MAA - B and MAA - C are observed to have a synergistic adhesion improvement effect.

[1033] In addition to the above - mentioned group of main organic and / or inorganic sunscreen UV filters, secondary sunscreen ingredients of the antioxidant type can also be advantageously used in the sunscreen products, cosmetic products or pharmaceutical preparations or household care products according to the present invention to further optimize the UV protection.

[1034] The secondary sunscreen ingredients of the antioxidant type interrupt the photochemical reaction chain triggered when UV rays penetrate the skin.

[1035] Typical examples of secondary sunscreen components are amino acids (e.g., arginine, lysine, glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (e.g., urocanic acid) and their derivatives, peptides such as D,L-carnosine, D-carnosine, L-carnosine and their derivatives (e.g., anserine), carotenoids, carotenes (e.g., α-carotene, β-carotene, lycopene) and their derivatives, chlorogenic acid and its derivatives, lipoic acid and its derivatives (e.g., dihydrolipoic acid), glucosinolate, propylthiouracil and other thiols (e.g., thioredoxin, glutathione, cysteine, cystine, cystamine and glycosyl, N-acetyl, methyl, ethyl, propyl, pentyl, butyl and lauryl, palmitoyl, oleyl, α-linolenoyl, cholesteryl and their glycerol esters) and their salts, very small compatible doses of dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and their derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) and sulfoximine compounds (e.g., buthionine sulfoximine, homocysteine sulfoximine, buthionine sulfone, pentathionic acid, hexathionic acid and heptathionic acid sulfoximine), and (metal) chelating agents (e.g., α-hydroxy fatty acids, palmitic acid, phytic acid, lactoferrin), α-hydroxy acids (e.g., citric acid, lactic acid, malic acid), humic acid, bile acids, bile extracts, bilirubin, biliverdin, EDTA, EGTA and their derivatives, unsaturated fatty acids and their derivatives (e.g., linoleic acid, oleic acid), folic acid and their derivatives, ubiquinone and panthenol and their derivatives, vitamin C and its derivatives (e.g., ascorbyl palmitate, Mg ascorbyl phosphate, ascorbyl acetate), tocopherols and their derivatives (e.g., vitamin E acetate), vitamin A and their derivatives (vitamin A palmitate) and coniferyl benzoate of benzoin resin, rutinic acid and their derivatives, glycosyl rutin, ferulic acid, glucofuranose, carnosine, butylated hydroxytoluene, butylated hydroxyanisole, nordihydroguaiaretic acid, nordihydroguaiaretic acid, trihydroxybutanone, uric acid and their derivatives, mannose and their derivatives, superoxide dismutase, sinapic acid, sinapoyl malate, sinapic acid ester derivatives, titanium dioxide (e.g., dispersion in ethanol), zinc and its derivatives (e.g., ZnO, ZnSO4), selenium and its derivatives (e.g., selenomethionine), stilbenes and their derivatives (e.g., oxidized stilbene, trans-oxidized stilbene) and derivatives (salts, esters, ethers, sugars, nucleotides, nucleosides, peptides and lipids) of these active substances suitable for the purposes of the present invention.

[1036] This group of secondary sunscreen ingredients also encompasses plant-based extracts. The plant-based extracts have antioxidant properties and generally have photoprotective properties and interrupt the chain of photochemical reactions triggered when UV rays penetrate the skin, and are thus effectively used to prevent skin aging. The plant extracts having UV protection properties are selected from the group consisting of: lignin / cellulose, lignin, hydrolyzed lignin, propolis and green propolis, lignin / cellulose, lignin, hydrolyzed lignin, propolis and green propolis, Alpinia officinarum extract, macro and microalgae (Porphyra, Bangia (Porphyra)), Palmaria palmata, Glycogenia spectabilis, Corallina officinalis, Ecklonia cava, Sargassum sagamianum, Porphyra rosenvinge, Sargassum carpaticola, Thalassiosira weissflogii, green microalgae (e.g., Interfilum and Kirchneriella), seaweeds (e.g., Padina australis, Eucheuma cottonii), Pongamia pinnata seed oil, Karanja oil (Erythrina indica oil), Dracaena extract (Rapatea extract), lichen, soybean, Capparis spinosa (caper), bamboo, raw coffee oil, Buriti oil (Mauritia flexuosa oil), Holothuria nobilis (black sea cucumber), cyanobacteria, Phlebodium aureum (golden polypody), green tea, black tea (Camellia sinensis var. assamica), aloe vera, walnut, borago oil, evening primrose oil, avocado oil, tea tree oil, red clover (Trifolium pratense), soybean (Glycine max), Capparis spinosa (caper), almond, Spathodea campanulata, milk thistle (Silybum marianum), cashew shell, grape, blood orange, pomegranate (Punicaceae), bilberry (Vaccinium myrtillus), bog bilberry (Vaccinium uliginosum), strawberry (Fragaria × ananassa), Polygonum multiflorum, turmeric (Curcuma longa), ginseng (Ginseng leaf saponins), English ivy (Hedera helix), broccoli (Brassica oleracea var. italica), tamarind (Tamarindus indica), Indian cactus, coffee, basil (Ocimum basilicum), pomegranate seed oil (Punica granatum), wheat germ oil (Triticum aestivum), blackcurrant seed oil (Ribes nigrum), bilberry (Vaccinium myrtillus), sesame oil (Sesamum indicum), carrot root (Daucus carota), raspberry seed oil (Rubus idaeus), traditional medicinal plants of Sri Lanka (Aporosa lindleyana (Euphorbiaceae), Atalantia ceylanica (Rutaceae), Sida acuta (Malvaceae), Oroxylum indicum (Oroxylaceae), Psychotria serpens (Rubiaceae), Argyreia nervosa (Convolvulaceae), Evolvulus alsinoides (Convolvulaceae), Arisaema tortuosum (Araceae), Artemisia vulgaris var. ceylanica (Lamiaceae), Delphinium ceylanicum (Lamiaceae) and Brazil (seeds of Centrolobium robustum, leaves of Pilea microphylla, Copaifera langsdorffii, Aspidosperma, Aspidosperma pyrifolium, Croton, Centrolobium robustum, Lippia microphylla, Luehea speciosa, Sida galheirensis) and any mixtures thereof.

[1037] Preferably, the plant extracts having UV protection properties are selected from the group consisting of: lignin / cellulose, lignin, hydrolyzed lignin, Alpinia officinarum extract, laver, Rhodophyta (Porphyra), green microalgae (e.g., Enteromorpha and Kirchneriella), seaweeds (e.g., Padina australis, Eucheuma cottonii), Pongamia pinnata seed oil, Karanja oil (Erythrina variegata oil), Dracaena extract (Raputia extract), soybeans, bamboo, Buriti oil (Mauritia flexuosa oil), cyanobacteria, Phlebodium aureum, green tea, black tea (Camellia sinensis var. assamica), aloe vera, evening primrose oil, cashew nut shell, pomegranate (Punicaceae), and any mixtures thereof.

[1038] Advantageously, based on the total weight of the ready-to-use formulation, the amount of the secondary sunscreen component in the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention is advantageously from 0.005% to 5.0% by weight, preferably from 0.01% to 4.0% by weight, and most preferably from 0.05% to 3.0% by weight.

[1039] The UV filters are incorporated into the aqueous or lipophilic part of the sunscreen product, cosmetic or pharmaceutical preparation or household care product depending on whether they are water- or oil (fat)-soluble / miscible UV filters, or can even be added to the final product by standard methods known to those skilled in the art.

[1040] Based on the total weight of the final formulation, at least one main organic and / or inorganic UV filter (a) according to the first aspect of the invention is present in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount from 0.01% to 80.0% by weight. In a preferred variant, based on the total weight of the final formulation, the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprises a main organic and / or inorganic UV filter (a) in an amount from 0.1% to 75.0% by weight. In a more preferred variant, based on the total weight of the final formulation, the UV filter is advantageously used in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount from 0.5% to 70.0% by weight. In the most preferred variant, based on the total weight of the final formulation, the UV filter is advantageously used in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount from 1.0% to 60.0% by weight.

[1041] For mixtures of main organic and / or inorganic UV filters, the above amounts relate to the total content of the UV filters in the mixture, i.e., the amount is the sum of the contents of all main UV filters in the mixture.

[1042] Based on the total weight of the final formulation, the main organic and / or inorganic UV filters (a) as defined herein and additional UV protection components, such as secondary sunscreen ingredients or secondary sunscreen UV filters (i.e., the total amount of UV filters), are present in the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention in an amount of from 0.1% by weight to 85.0% by weight. In a preferred variant, based on the total weight of the final formulation, the sunscreen product, cosmetic or pharmaceutical preparation comprises an amount of from 0.3% by weight to 80.0% by weight of the main organic and / or inorganic UV filters (a) as defined herein and additional UV protection components. In a more preferred variant, based on the total weight of the final formulation, the UV filters (a) as defined herein and additional UV protection components are advantageously used in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount of from 0.5% by weight to 75.0% by weight. Thus, the above amounts relate to the sum of the contents of all UV filters / UV protection components present in the sunscreen or cosmetic or pharmaceutical preparation.

[1043] Based on the total weight of the final formulation, at least one mycosporine-like amino acid compound (b) according to the first aspect of the invention is present in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount of from 0.001% by weight to 15.0% by weight. In a preferred variant, based on the total weight of the final formulation, the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprises an amount of from 0.01% by weight to 10.0% by weight of at least one mycosporine-like amino acid compound (b). In a more preferred variant, based on the total weight of the final formulation, at least one mycosporine-like amino acid compound (b) is advantageously used in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount of from 0.05% by weight to 7.5% by weight. In a most preferred variant, based on the total weight of the final formulation, at least one mycosporine-like amino acid compound (b) is advantageously used in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount of from 0.1% by weight to 5.0% by weight.

[1044] For a mixture of mycosporine-like amino acid compounds I, the above amounts relate to the total content of mycosporine-like amino acid compounds in the mixture, i.e., the amount is the sum of the contents of all mycosporine-like amino acid compounds (b) in the mixture.

[1045] Based on the total weight of the final formulation, the at least one film-forming agent (c) according to the first aspect of the present invention is present in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount from 0.01% to 10.0% by weight. In a preferred variant, based on the total weight of the final formulation, the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprises a film-forming agent I in an amount from 0.05% to 8.0% by weight. In a most preferred variant, based on the total weight of the final formulation, the film-forming agent I is advantageously used in the sunscreen product, cosmetic or pharmaceutical preparation or household care product in an amount from 0.1% to 5.0% by weight.

[1046] For a mixture of film-forming agents, the above amounts relate to the total content of the film-forming agents in the mixture, i.e. the amount is the sum of the contents of all film-forming agents in the mixture.

[1047] Advantageously, the sunscreen product according to the first aspect of the present invention comprises

[1048] (i) from 0.01% to 80.0% by weight of a major organic and / or inorganic UV filter;

[1049] (ii) from 0.001% to 15.0% by weight of at least one mycosporine-like amino acid compound as defined herein; and

[1050] (iii) optionally from 0.01% to 10.0% by weight of at least one film-forming agent;

[1051] Based on the total weight of the final formulation.

[1052] In a preferred variant, the cosmetic or pharmaceutical preparation according to the first aspect of the present invention comprises

[1053] (iv) from 1.0% to 60.0% by weight of at least one major organic and / or inorganic UV filter;

[1054] (v) from 0.1% to 5.0% by weight of at least one mycosporine-like amino acid compound as defined herein; and

[1055] (vi) optionally from 0.1% to 5.0% by weight of at least one film-forming agent;

[1056] Based on the total weight of the final formulation.

[1057] The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention provides a broader range of photoprotection and thus provides protection against both UVA and UVB radiation. The sun protection factor (SPF) is a measure of UVB protection. Generally, the compositions of the invention have an SPF of at least 6. However, the SPF can vary as needed. The type and amount of UVA and UVB filters can be varied to obtain the desired SPF level. Preferably, the SPF of the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention is at least 6, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80 or even higher.

[1058] In the context of the present invention, it may also be possible and in some cases advantageous to combine the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the first aspect of the invention with other conventional active substances, adjuvants or additives conventionally used in sunscreen products, cosmetics or pharmaceutical compositions or household care products as further described below in order to obtain ready-to-use formulations or preparations.

[1059] Other active agents and / or adjuvants and / or additives or auxiliaries are, for example, abrasives, anti-acne agents, anti-skin aging agents, anti-cellulitis agents, anti-dandruff agents, anti-inflammatory agents, anti-irritants, irritation inhibitors, antioxidants, alkanediols, astringents, odor absorbers, antiperspirants, preservatives, antistatic agents, antibacterial agents, binders, buffers, carrier materials, oil components, chelating agents, cell stimulants, detergents, depilatories, surface active substances, deodorants, antiperspirants, emollients, emulsifiers, enzymes, enzyme inhibitors, essential oils, fibers, film formers, water resistance improvers, fixatives, foaming agents, foam stabilizers, anti-foaming substances, foam boosters, gelling agents, gel formers, hair care agents, hair styling agents, hair straightening agents, moisture suppliers, moisturizing substances, water-retaining substances, bleaching agents, strengthening agents, detergents, optical brighteners, impregnating agents, soil repellents, dyes, friction reducers, lubricants, moisturizing creams, ointments, sunscreens, plasticizers, covering agents, polishing agents, preservatives, brighteners, green and synthetic polymers, powders, proteins, re-oiling agents, abrasives, silicones, skin soothers, skin detergents, skin care agents, skin healing agents, skin brighteners, skin protectants, skin emollients, hair growth promoters, cooling agents, skin cooling agents, warming agents, skin warming agents, stabilizers, surface active agents, antibacterial agents, detergents / surface active agents, fabric conditioners, suspending agents, skin tanning agents, active substances for regulating skin or hair pigmentation, matrix metalloproteinase inhibitors, skin moisturizers, glycosaminoglycan stimulants, TRPV1 antagonists, desquamating agents, anti-cellulite agents or cellulite boosters, hair growth activators or inhibitors, thickeners, rheological additives, vitamins, oils, waxes, pearlescent waxes, fats, phospholipids, saturated fatty acids, mono- or polyunsaturated fatty acids, alpha-hydroxy acids, polyhydroxy fatty acids, liquefiers, dyes, color protectants, pigments, preservatives, fragrances or perfume oils, flavorings, odoriferous substances, polyols, electrolytes, organic solvents and mixtures of two or more of the above substances, as further described below.

[1060] The above cosmetic or pharmaceutical excipients and / or active substances and / or additives and / or auxiliary carriers, oil components, rheological additives, hydrotropes, solubilizers, powders, film formers, water resistance improvers, skin moisturizing and / or water-retaining substances, soothing substances, physiological cooling agents, alkanediols, antioxidants, anti-skin aging agents, matrix metalloproteinase inhibitors (MMPI), anti-inflammatory agents, TRPV1 antagonists, emulsifiers, antimicrobial agents, preservatives, antibacterial or antifungal active substances, chelating agents, surface active agents, fragrances / perfume oils or perfume oils, and any mixtures of two or more of the above substances are particularly preferred in the preparation of sunscreen products, cosmetics and pharmaceutical preparations or household care products.

[1061] Carriers: As sunscreen products, cosmetics or pharmaceutical (especially dermatological) preparations or household care products as defined herein are intended for topical application, for example, in the form of ointments, pastes, creams and gels, and they are preferably based on carriers. The most common acceptable carrier is water. In addition to water, acceptable carriers include glycerol, C1-C4 alcohols, organic solvents, fatty alcohols, fatty ethers, fatty esters, polyols, ethylene glycol, vegetable oils, mineral oils, liposomes, lamellar lipid materials, water or mixtures thereof. Non-limiting examples of organic solvents include monoalcohols and polyols, such as ethanol, isopropanol, propanol, benzyl alcohol and phenethyl alcohol, or ethylene glycol or ethylene glycol ethers, such as, for example, mono-methyl, mono-ethyl and mono-butyl ethers of ethylene glycol, propylene glycol or their ethers, such as, for example, propylene glycol, butylene glycol, hexylene glycol, monomethyl ether of dipropylene glycol and alkyl ethers of diethylene glycol, such as, for example, mono-ethyl ether or mono-butyl ether of diethylene glycol. Other examples of suitable organic solvents are ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, propylene glycol and glycerol. The organic solvent can be a volatile or non-volatile compound. The total amount of the carrier in the composition can vary, but is usually 40% to 90% by weight based on the total weight of the composition.

[1062] The product or preparation of the present invention may include at least one water-soluble or organic solvent. Non-limiting examples of organic solvents include monoalcohols and polyols, such as ethanol, isopropanol, propanol, benzyl alcohol and phenethyl alcohol, or ethylene glycol or ethylene glycol ethers, such as, for example, mono-methyl, mono-ethyl and mono-butyl ethers of ethylene glycol, propylene glycol or their ethers, such as, for example, propylene glycol, butylene glycol, hexylene glycol, monomethyl ether of dipropylene glycol and alkyl ethers of diethylene glycol, such as, for example, mono-ethyl ether or mono-butyl ether of diethylene glycol. Other examples of suitable organic solvents are ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, propylene glycol and glycerol. The organic solvent can be a volatile or non-volatile compound.

[1063] Additional non-limiting examples of water-soluble solvents include alkanols (polyhydric alcohols such as ethylene glycol and polyhydric alcohols), such as glycerol, 1,2,6-hexanetriol, trimethylolpropane, ethylene glycol, propylene glycol, diethylene glycol, butylene glycol, hexylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 1,3-butanediol, 2,3-butanediol, 1,4-butanediol, 3-methyl-1,3-butanediol, 1,5-pentanediol, tetraethylene glycol, 1,6-hexanediol, 2-methyl-2,4-pentanediol, polyethylene glycol, 1,2,4-butanetriol, 1,2,6-hexanetriol, 2-butene-1,4-diol, 2-ethyl-1,3-hexanediol, 2-methyl-2,4-pentanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-decanediol, and 4-methyl-1,2-pentanediol; alkyl alcohols having 1 to 4 carbon atoms, such as ethanol, methanol, butanol, propanol, and isopropanol; ethylene glycol ethers, such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monomethyl ether acetate, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monon-propyl ether, ethylene glycol monoisopropyl ether, diethylene glycol monoisopropyl ether, ethylene glycol monon-butyl ether, ethylene glycol monotert-butyl ether, diethylene glycol monotert-butyl ether, 1-methyl-1-methoxybutanol, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monotert-butyl ether, propylene glycol monon-propyl ether, propylene glycol monoisopropyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, dipropylene glycol monon-propyl ether, and dipropylene glycol monoisopropyl ether; 2-pyrrolidone, N-methyl-2-pyrrolidone, 1,3-dimethyl-2-imidazolidinone, formamide, acetamide, dimethyl sulfoxide, sorbitol, sorbitan, ethyl acetate, diethyl acetate, triethyl acetate, sulfolane, and mixtures thereof. The total amount of the water-soluble solvent or organic solvent in the composition according to the present invention may vary, but is generally 0.1% by weight to 50% by weight based on the total weight of the composition.

[1064] Solubilizer: The products or formulations of the present invention may include at least one solubilizer. A solubilizer is a compound that aids in dissolving the UV filter and / or other components in the composition. Particularly useful but non-limiting examples of solubilizers are hydrotropes. Hydrotropes (or hydrotropic reagents) are a diverse class of typically water-soluble compounds, which may be characterized by an amphiphilic molecular structure and the ability to significantly increase the solubility of sparingly soluble organic molecules in water. Non-limiting examples of hydrotropes include sodium 1,3-benzenedisulfonate, sodium benzoate, sodium 4-pyridinecarboxylate, sodium salicylate, sodium benzenesulfonate, caffeine, sodium p-toluenesulfonate, sodium butylmonoglycol sulfate, 4-aminobenzoic acid HCI, sodium cumenesulfonate, N,N-diethylnicotinamide, N-picolinylnicotinamide, N-allylnicotinamide, 2-methacryloyloxyethyl phosphorylcholine, resorcinol, butylurea, pyrogallol, N-picolinylethylamide 3.5, procaine HCI, proline HCI, nicotinamide, pyridine, 3-pyridylmethylamine, sodium ibuprofen, sodium xylenesulfonate, ethyl carbamate, pyridoxal hydrochloride, sodium benzoate, 2-pyrrolidone, ethylurea, N,N-dimethylacetamide, N-methylacetamide, and isoniazid and any mixtures thereof. In some cases, particularly useful hydrotropes include nicotinamide (niacinamide), caffeine, sodium PCA, sodium salicylate, urea, and dihydroxyethylurea, particularly nicotinamide (niacinamide) and / or caffeine. Combinations of two or more, three or more, or four or more hydrotropes may also be used in the compositions according to the present invention. The total amount of the solubilizer in the compositions of the present invention may vary, but is typically in an amount of from 0.01% to 20% by weight, based on the total weight of the composition.

[1065] Oil component: The sunscreen product, cosmetic or pharmaceutical formulation, or household care product may include at least one oil phase or at least one oil component, wax, starch, tragacanth, cellulose derivatives, polyethylene glycol, silicone, bentonite, silica, talc, and zinc oxide, or any mixtures thereof. Powders include carriers such as lactose, talc, silica, aluminum hydroxide, calcium silicate, and polyamide powder, or any mixtures thereof. Solutions and emulsions include carriers such as solvents such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, propylene glycol, etc., or any mixtures thereof. However, water-only formulations are also possible. Oils, oil-in-water, and water-in-oil emulsions, etc. are preferred.

[1066] Suitable oil phases or oil components in the sunscreen product, cosmetic or pharmaceutical formulation, or household care product according to the present invention are, for example, vegetable oils, hydrocarbons, fatty alcohols, fatty acid esters, or mixtures of two or more of the aforementioned oil components.

[1067] The oil phase or oil component in a sunscreen product, cosmetic or pharmaceutical preparation or household care product is preferably a vegetable oil, and even more preferably a liquid vegetable oil. It may also advantageously be a mixture of two or more vegetable oil components, especially a mixture of liquid vegetable oils.

[1068] Vegetable oil or vegetable fat is oil extracted from seeds, or less commonly from other parts of fruits. Like animal fats, vegetable oils are mixtures of triglycerides. Soybean oil, rapeseed oil and cocoa butter are examples of vegetable oils from seeds. Olive oil, palm oil and rice bran oil are examples of oils from other parts of fruits. In common usage, vegetable oil or vegetable fat may specifically refer to vegetable fats that are liquid at room temperature or at skin temperature of 35 °C to 37 °C. Vegetable oils are generally edible.

[1069] The term "vegetable oil" also includes unsaturated vegetable oils. Unsaturated oils or vegetable fats can be converted into oils with higher melting points by partial or complete "hydrogenation". The hydrogenation process involves "spraying" the oil with hydrogen at high temperature and pressure in the presence of a catalyst (usually a powdered nickel compound). When each carbon-carbon double bond is chemically reduced to a single bond, two hydrogen atoms each form a single bond with two carbon atoms. The process of eliminating double bonds by adding hydrogen atoms is called saturation; as the degree of saturation increases, the oil is gradually fully hydrogenated. Oils can be hydrogenated to increase resistance to rancidity (oxidation) or to change their physical properties. As the degree of saturation increases, the viscosity and melting point of the oil increase.

[1070] In a preferred variant, the vegetable oils are selected from the group consisting of: avocado (Persea gratissima oil), abies alba seed oil, acacia victoriae seed oil, kiwi (Actinidia deliciosa) seed oil, amaranth seed oil, peanut (Arachis hypogaea) oil, murumuru seed butter, tucuma seed butter, tucuma seed oil, asteropeia hypogaea fruit oil, asteropeia hypogaea kernel oil, oat (Avena sativa) bran powder kernel oil, white mustard (Sinapis alba) seed oil, rapeseed (Brassica napus) oil, shea (Vitellaria paradoxa) butter, shea (Vitellaria paradoxa) oil, calendula (Calendula officinalis) seed oil, calophylum inophyllum seed oil, tagetes lucida seed oil, camellia (Camellia oleifera) seed oil, camellia reticulata seed oil, tea (Camellia sinensis) seed oil, rapeseed oil, safflower (Carthamus tinctorius) seed oil, chlorella oil, cucurbitaceae watermelon (Citrullus lanatus) seed oil, lime (Citrus aurantifolia) seed oil, sweet orange (Citrus sinensis) seed oil, grapefruit (Citrus paradisi) seed oil, coco (Cocos nucifera) oil, palmaceae coconut (Cocos nucifera) seed butter, rubiaceae coffee (Coffea arabica) seed oil, chlorella oil (biotechnology), hazelnut (Corylus americana) seed oil, hazelnut (Corylus avellana) seed oil, melon (Cucumis melo) seed oil, cucumber (Cucumis sativus) seed oil, zucchini (Cucurbita pepo) seed oil, oil palm (Elaeis guineensis) oil, oil palm (Elaeis guineensis) fruit oil, soybean (Glycine max) oil, malvaceae cotton (Gossypium herbaceum) seed oil, malvaceae cotton (Gossypium herbaceum) seed oil, asteraceae (Helianthus annuus) seed oil, macadamia (Macadamia integrifolia) seed oil, macadamia (Macadamia tetraphylla) seed oil, mango (Mangifera indica) seed butter, mango (Mangifera indica) seed oil, melissa (Melissa officinalis) seed oil, microalgae oil, moringa (Moringa oleifera) seed oil, moringa (Moringa oleifera) seed oil, evening primrose (Oenothera biennis) oil, olive (Olea europaea) fruit oil, rice (Oryza sativa) bran / germ oil, rice (Oryza sativa) bran oil, rice (Oryza sativa) germ oil, rice (Oryza sativa) lipids, rice (Oryza sativa) seed oil, passion fruit (Passiflora edulis) seed oil, avocado (Persea gratissima) butter, avocado (Persea gratissima) oil, almond (Prunus dulcis) oil, apricot (Prunus armeniaca) kernel oil, peach (Prunus persica) kernel oil, pomegranate (Punica granatum) seed oil, apple (Malus domestica) seed oil, castor oil / caprylic / capric / capric triglyceride, castor (Ricinus communis) seed oil, dog rose (Rosa canina) fruit oil, musk rose (Rosa moschata) seed oil, raspberry (Rubus idaeus) seed oil, sesame (Sesamum indicum) seed butter, soy glycerides, cocoa (Theobroma cacao) seed butter, theobroma grandiflorum seed butter, wheat (Triticum aestivum) bran sebum lipids, wheat (Triticum aestivum) germ oil, grape (Vitis vinifera) seed oil, corn (Zea mays) germ oil and corn (Zea mays) oil.

[1071] The vegetable oils specified above are the most common natural lipid components used as the basic substances for manufacturing cosmetic or pharmaceutical formulations.

[1072] Hydrocarbons (mineral oils) are generally organic compounds consisting entirely of hydrogen and carbon. As defined according to IUPAC nomenclature or organic chemistry, the classification of hydrocarbons is as follows:

[1073] 1. Saturated hydrocarbons are the simplest hydrocarbon substances. They consist entirely of single bonds and are saturated with hydrogen. The formula for acyclic saturated hydrocarbons (i.e., alkanes) is C n H 2n+2 . The most general form of saturated hydrocarbons is C n H 2n+2(1-r), where r is the number of rings. Hydrocarbons with exactly one ring are cycloalkanes. Saturated hydrocarbons are the basis of petroleum fuels and are found to have straight or branched chains.

[1074] 2. Unsaturated hydrocarbons have one or more double or triple bonds between carbon atoms. Hydrocarbons with double bonds are called alkenes. Hydrocarbons with one double bond have the formula C n H 2n (assuming a non-cyclic structure). Hydrocarbons containing triple bonds are called alkynes. Hydrocarbons with one triple bond have the formula C n H 2n-2 .

[1075] 3. Aromatic hydrocarbons (also called arenes) are hydrocarbons with at least one aromatic ring.

[1076] Hydrocarbons can especially be liquids (e.g., hexane and benzene), waxes or low-melting solids (e.g., paraffin wax and naphthalene). The term "aliphatic" refers to non-aromatic hydrocarbons. Saturated aliphatic hydrocarbons are sometimes called "paraffins". Mineral oils and waxes are mixtures mainly of saturated hydrocarbons consisting of straight, branched and cyclic structures with a carbon chain length greater than C14. Mineral oils and waxes are chemical substances separated from naturally occurring crude oil. They mainly consist of mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH). For decades, hydrocarbons have been used in skin and lip care cosmetic products due to their excellent skin tolerance, high protective and cleansing properties and wide viscosity options. Unlike vegetable oils, mineral oils do not cause allergies because they are highly stable and not prone to oxidation or rancidity.

[1077] Fatty alcohols (or long-chain alcohols) are generally high-molecular-weight straight-chain primary alcohols derived from natural fats and oils, but can range from as few as 4 to 6 carbons to as many as 22 to 26 carbons. The exact chain length varies depending on the source. Some commercially important fatty alcohols are lauryl alcohol, stearyl alcohol, and oleyl alcohol. They are colorless oily liquids (for smaller carbon numbers) or waxy solids, but impure samples may appear yellow. Fatty alcohols typically have an even number of carbon atoms and a single alcohol group (-OH) attached to the terminal carbon. Some fatty alcohols are unsaturated, and some are branched. Most fatty alcohols are found in nature as waxes, which are esters of fatty acids and fatty alcohols. The traditional sources of fatty alcohols are mostly various vegetable oils, and these remain the major raw materials on a large scale. The alcohols are obtained from triglycerides (triesters of fatty acids), which are the main components of oils. The method involves transesterification of the triglycerides to obtain methyl esters, and then the methyl esters are hydrogenated to obtain fatty alcohols. Fatty alcohols can also be prepared from petrochemical sources. In the Ziegler process, triethylaluminum is used to oligomerize ethylene, followed by air oxidation. Alternatively, ethylene can be oligomerized to obtain a mixture of olefins, the mixture is hydroformylated, which yields aldehydes with odd numbers, and subsequently the aldehydes are hydrogenated. Fatty alcohols are mainly used in the production of detergents and surfactants. They are also components of cosmetic solvents. They are used as co-emulsifiers, emollients, and thickeners in cosmetics.

[1078] In a preferred variant, the fatty alcohol is selected from the group consisting of phenylpropanol, dimethylphenylbutanol, hexyl decanol, octyldodecanol, octyldecanol, tridecanol, isostearyl alcohol, phenylisohexanol, phenylpropanol, trimethylphenylpropanol, isopentanol, isostearyl alcohol, and isotridecanol. In a more preferred variant, the fatty alcohol is selected from the group consisting of hexyl decanol, octyldodecanol, phenylpropanol, isopentanol, and mixtures of two or more of the above fatty alcohols. The fatty alcohol can be used as a single component or in admixture with one or more other different fatty alcohols as specified above.

[1079] Fatty acid esters are a type of ester produced by the combination of fatty acids and alcohols. When the alcohol component is glycerol, the resulting fatty acid esters can be monoglycerides, diglycerides, or triglycerides. Fatty acid esters have a conditioning effect of softening the skin to produce a smooth feel. They are also added to cosmetics to dissolve highly polar active ingredients and UV absorbers. Esters of straight-chain fatty acids and lower alcohols are effective in dissolving slightly soluble components in oils, which can be easily touched during application. Isooctyl stearate and other liquid oils with branched and unsaturated fatty acids are commonly used as emollients. Esters of higher fatty acids and higher alcohols with relatively high melting points are added to skin creams to adjust the application feel.

[1080] Oil Bodies and Emollients: In addition to the oil phase or oil components as defined above, the sunscreen products, cosmetic or pharmaceutical preparations or household care products according to the invention preferably comprise one or more oil bodies or emollients. An emollient is an oily or greasy substance that helps to smooth and soften the skin and can also reduce skin roughness, cracking or irritation. In particular, in sunscreen products, emollients counteract the known stickiness of some UV filters and keep crystalline and oil-soluble organic and inorganic UV filters dissolved and prevent them from recrystallizing. Additionally, emollients act as wetting agents for inorganic UV filters for uniform dispersion in the formulation. Suitable oil bodies for forming O / W emulsions are, for example, Guerbet alcohols based on fatty alcohols having 6 to 18, preferably 8 to 10 carbon atoms, esters of straight-chain C5-C22 fatty acids with straight-chain or branched C5-C22 fatty alcohols, or esters of branched C1-C13 carboxylic acids with straight-chain or branched C6-C22 fatty alcohols, such as, for example, myristyl myristate, cetyl myristate, stearyl myristate, isostearyl myristate, oleyl myristate, behenyl myristate, erucyl myristate, myristyl cetylate, cetyl cetylate, stearyl cetylate, isostearyl cetylate, oleyl cetylate, behenyl cetylate, erucyl cetylate, myristyl stearate, cetyl stearate, stearyl stearate, isostearyl stearate, oleyl stearate, behenyl stearate, erucyl stearate, myristyl isostearate, cetyl isostearate, stearyl isostearate, isostearyl isostearate, oleyl isostearate, behenyl isostearate, oleyl isostearate, myristyl oleate, cetyl oleate, stearyl oleate, isostearyl oleate, oleyl oleate, behenyl oleate, erucyl oleate, myristyl behenate, cetyl behenate, stearyl behenate, isostearyl behenate, oleyl behenate, behenyl behenate, behenyl erucate, myristyl erucate, cetyl erucate, stearyl erucate, isostearyl erucate, oleyl erucate, behenyl erucate and erucyl erucate. Also suitable are esters of straight-chain C6-C22 fatty acids with branched alcohols, especially 2-ethylhexanol, esters of C18-C38 alkyl hydroxycarboxylic acids with straight-chain or branched C6-C22 fatty alcohols, especially dioctyl malate, esters of straight-chain and / or branched fatty acids with polyols (such as, for example, propylene glycol, dimerol or trimerol) and / or Guerbet alcohols, triglycerides based on C6-C10 fatty acids, liquid mono- / di- / triglyceride mixtures based on C6-C18 fatty acids, esters of C6-C22 fatty alcohols and / or Guerbet alcohols with aromatic carboxylic acids, especially benzoic acid, esters of C2-C12 dicarboxylic acids with straight-chain or branched alcohols having 1 to 22 carbon atoms or polyols having 2 to 10 carbon atoms and 2 to 6 hydroxy groups, vegetable oils, branched primary alcohols, substituted cyclohexanes, straight-chain and branched C6-C22 fatty alcohol carbonates such as, for example, dicaprylyl carbonate ( (CC), Guerbet carbonates based on fatty alcohols having 6 to 18, preferably 8 to 10 carbon atoms, benzoates of linear and / or branched C6-C 22 -alcohols (e.g. (TN), linear or branched, symmetric or asymmetric dialkyl ethers in which each alkyl group has 6 to 22 carbon atoms such as, for example, dioctyl ether ( (OE), ring-opening products of epoxidized fatty acid esters with polyols, silicone oils (cyclomethicone, silicone methylsiloxane grades, etc.) and / or aliphatic or cycloaliphatic hydrocarbons such as, for example, 159amascen, squalene or dialkylcyclohexane and any mixtures thereof.

[1081] Powders: The compositions as defined herein may optionally include powders. The optional powders provide formulations that make the skin smoother and softer. Representative powders include talc, mica, magnesium carbonate, calcium carbonate, magnesium silicate, magnesium aluminum silicate, silica, titanium dioxide, zinc oxide, iron oxide red, iron oxide yellow, iron oxide black, polyethylene powder, methacrylate powder, polystyrene powder, silk powder. Preferred solid powder materials that can be components of the compositions according to the invention are hydrocolloids such as starch, degraded starch, chemically or physically modified starch, dextrin, (powdered) maltodextrin (preferably having a dextrose equivalent value of 5 to 25, preferably 10 - 20), lactose, silica, glucose, modified cellulose, gum arabic, gum ghatti, gum tragacanth, carrageenan, amylopectin, gellan gum, xanthan gum, gellan gum, guar flour, locust bean flour, alginates, agar, pectin, inulin and mixtures of two or more of these solids (preferably having a dextrose equivalent value of 15 - 20), lactose, silica and / or glucose.

[1082] Rheology modifiers: The sunscreen products, cosmetic or pharmaceutical formulations or household care products according to the invention advantageously include one or more thickeners and / or rheology modifiers. The rheology modifier is present in an amount that prevents the composition from significantly dripping or aggregating after application to the skin. Preferably, the rheology modifier is carbomer. In some embodiments, the rheology modifier is selected from stearic acid, palmitic acid, stearyl alcohol, cetyl alcohol, behenyl alcohol, stearic acid, palmitic acid, polyethylene glycol ethers of stearyl alcohol having on average from about 1 to about 21 ethylene oxide units, polyethylene glycol ethers of cetyl alcohol having on average from about 1 to about 5 ethylene oxide units and mixtures thereof.

[1083] Additional examples of rheology modifiers include thickeners or gelling agents, including substances that can increase the viscosity of the composition. Thickeners include those substances that can increase the viscosity of the composition without substantially changing the efficacy of the active ingredients in the formulation. Thickeners can also increase the stability of the formulations of the present application. In certain aspects of the present application, thickeners include hydrogenated polyisobutene or trimethylol stearin, or a mixture of both. Additional non-limiting examples of thickeners that can be used in the context of the present application include carboxylic acid polymers, cross-linked polyacrylate polymers, polyacrylamide polymers, polysaccharides, and gums. Examples of carboxylic acid polymers include cross-linked compounds containing one or more monomers derived from acrylic acid, substituted acrylic acids, and salts and esters of these acrylic acids and substituted acrylic acids, wherein the cross-linking agent contains two or more carbon-carbon double bonds and is derived from a polyol (see CTFA International Cosmetic Ingredient Dictionary, Fourth Edition, 1991, pages 12 and 80). Examples of commercially available carboxylic acid polymers include carbomers, which are homopolymers of acrylic acid cross-linked with allyl ethers of sucrose or pentaerythritol (e.g., Carbopol TM from B.F. Goodrich, 900 series). Non-limiting examples of cross-linked polyacrylate polymers include cationic polymers and non-ionic polymers.

[1084] Non-limiting examples of polyacrylamide polymers (including non-ionic polyacrylamide polymers, including substituted branched or linear polymers) include polyacrylamide, isoparaffin, and laureth-7, polyacrylamide, and multi-block copolymers of substituted acrylamides with acrylic acid and substituted acrylic acids.

[1085] Non-limiting examples of polysaccharides include cellulose, carboxymethyl hydroxyethyl cellulose, cellulose acetate propionate carboxylate, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, methyl hydroxyethyl cellulose, microcrystalline cellulose, sodium cellulose sulfate, and mixtures thereof. Another example is alkyl-substituted cellulose, where the hydroxyl groups of the cellulose polymer are hydroxyalkylated (preferably hydroxyethylated or hydroxypropylated) to form hydroxyalkylated cellulose, which is then further modified with C10-C30 linear or branched alkyl groups via ether bonds. Generally, these polymers are ethers of C10-C30 linear or branched alcohols with hydroxyalkyl cellulose. Other useful polysaccharides include curdlan, which consists of linear chains of (1 to 3) linked glucose units, with one (1 to 6) linked glucose every three units.

[1086] Non-limiting examples of gums that can be used with the compositions of the present invention include gum arabic, agar, alginate, alginic acid, ammonium alginate, amylopectin, calcium alginate, calcium carrageenan, carnitine, carrageenan, dextrin, gelatin, gellan gum, guar gum, guar gum hydroxypropyltrimethylammonium chloride, lithium montmorillonite, hyaluronic acid, hydrated silica, hydroxypropyl chitosan, hydroxypropyl guar gum, karaya gum, laminaria, locust bean gum, natto gum, potassium alginate, potassium carrageenan, propylene glycol alginate, scleroglucan, sodium carboxymethyl dextran, sodium carrageenan, tragacanth gum, xanthan gum, and mixtures thereof. In one embodiment, the thickener is carrageenan extract.

[1087] Water resistance improver: The sunscreen product, cosmetic or pharmaceutical formulation or household care product according to the present invention may advantageously include one or more reagents for improving water resistance. The reagent for improving water resistance is a hydrophobic material that imparts film-forming properties and water resistance properties to the emulsion. Typical suitable water resistance improvers include copolymers derived from the polymerization of octadecene-1 and maleic anhydride. A preferred water resistance improver is a polyanhydride resin. Another preferred water resistance improver is a copolymer of vinylpyrrolidone and 162amascen monomer. The water resistance improver is used in an amount that effectively retains the final formulation on the skin or surface after exposure to circulating water for at least 40 minutes, preferably 80 minutes. Based on the total weight of the final formulation, one or more water resistance improvers may optionally be included in the final formulation in an amount ranging from 0.01% to 10.0% by weight, preferably from 0.05% to 8.0% by weight, more preferably from 0.1% to 5.0% by weight.

[1088] Silicone: To impart a smooth, spreadable and luxurious texture and make the skin look and feel smoother, and also to improve processability (defoaming), the sunscreen product, cosmetic or pharmaceutical formulation or household care product according to the present invention preferably includes one or more silicones or silicone derivatives. The total amount of silicone compounds in the composition according to the present invention may vary, but is generally 0.1% to 35.0% by weight based on the total weight of the composition.

[1089] Dryness modifier: The sunscreen product, cosmetic or pharmaceutical formulation according to the present invention is preferably combined with a dryness modifier. A dryness modifier is a reagent that imparts a "dry feeling" to the skin when incorporated into the emulsion and dried. The dryness modifier can also reduce the migration of the sunscreen on the skin. The dryness modifier may include starch, talc, kaolin, chalk, zinc oxide, hydroxyapatite (such as Tinomax CC), silicone fluid, inorganic salts (such as barium sulfate and sodium chloride), C6 to C12 alcohols (such as octanol); sulfonated oil; surface-treated silica, precipitated silica, calcined silica, such as those available from Degussa Inc. of New York, USA or mixtures thereof; dimethicone, i.e., a mixture of methylated linear silicone polymers, available as DC200 fluid, under the trade name of Dow Corning, Midland, Mich., U.S.A. One or more dryness modifiers may optionally be included in the sunscreen in an amount ranging from 0.01% to 20% by weight, more preferably from 0.1% to 10.0% by weight.

[1090] Skin moisturizing substances and / or water-retaining substances: The sunscreen product or cosmetic or pharmaceutical preparation according to the present invention advantageously includes one or more skin moisturizing substances and / or water-retaining substances. Preferred skin moisturizing substances and / or water-retaining substances are selected from the group consisting of alkanediols or alkanetriols having 3 to 12 carbon atoms, preferably C3-C 10 -alkanediols and C3-C 10 -alkanetriols. More preferably, the skin moisturizer is selected from the group consisting of glycerol, 1,2-propanediol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, and 1,2-decanediol. Additional skin moisturizing substances and / or water-retaining substances include sodium lactate, urea, urea derivatives, alcohols, glycerol, diols (such as propylene glycol, hexylene glycol), collagen, elastin, or hyaluronic acid, diacyl adipates, petrolatum, urocanic acid, lecithin, panthenol, phytantriol, lycopene, (pseudo)ceramides, glycosphingolipids, cholesterol, phytosterols, chitosan, 163amascenetin sulfate, lanolin, lanolin esters, amino acids, α-hydroxy acids (such as citric acid, lactic acid, malic acid) and their derivatives, monosaccharides, disaccharides, and oligosaccharides (such as glucose, galactose, fructose, mannose, fructose, and lactose), polysaccharides (such as R-glucan), especially 1,3-1,4-β-glucan from oats, α-hydroxy fatty acids, triterpenic acids (such as betulinic acid or ursolic acid), and algae extracts.

[1091] Soothing substances: The sunscreen product or cosmetic or pharmaceutical preparation according to the present invention may also advantageously contain one or more soothing substances, and any soothing substances suitable or commonly used in cosmetic or pharmaceutical applications may be used, such as α-bisabolol, azulene, guaiene, 18-β-glycyrrhetinic acid, allantoin, aloe vera juice or gel, witch hazel (Hamamelis virginiana), Echinacea spp., Centella asiatica, chamomile, arnica, Glycyrrhiza spp., algae, seaweed, and calendula extracts, as well as vegetable oils (such as sweet almond oil, baobab oil), olive oil, and panthenol, laureth-9, trideceth-9, and 4-tert-butylcyclohexanol.

[1092] Physiological cooling agents: The sunscreen products, cosmetics or pharmaceutical preparations according to the present invention can be particularly advantageously combined with one or more physiological cooling agents. The use of cooling agents can relieve itching. The preferred individual coolants used within the scope of the present invention are listed below. Those skilled in the art can add many other coolants to this list; the listed coolants can also be used in combination with each other, and these coolants are preferably selected from the following list: menthol and menthol derivatives (such as L-menthol, D-menthol, racemic menthol, isomenthol, neoisomenthol), menthol ethers (such as (I-menthoxy)-1,2-propanediol, (L-menthoxy)-2-methyl-1,2-propanediol, l-menthyl methyl ether), menthone glycerol acetal, menthone glycerol ketal or a mixture of both, menthol esters (such as menthyl formate, menthyl acetate, menthyl isobutyrate, hydroxyisobutyric acid menthyl ester, menthyl lactate, L-menthyl-L-lactate, L-menthyl-D-lactate, menthyl-(2-methoxy)acetate, menthyl-(2-methoxyethoxy)acetate, pyroglutamic acid menthyl ester), carbonic acid menthyl esters (such as menthyl propylene glycol carbonate, menthyl ethylene glycol carbonate, menthyl glycerol carbonate or mixtures thereof), half esters of menthol with dicarboxylic acids or their derivatives (such as monomenthyl succinate, monomenthyl glutarate, monomenthyl malonate, O-menthyl succinate-N,N-(dimethyl)amide, O-menthyl succinate amide), menthane carboxylic acid amides (in this case preferably menthane carboxylic acid-N-ethylamide [WS3] or N α-(menthane-carbonyl) glycidyl ester [WS5], menthane carboxylic acid-N-(4-cyanophenyl) amide or menthane formic acid-N-(-4-cyanomethylphenyl) amide, menthane carboxylic acid-N-(alkoxyalkyl) amide), menthone and menthone derivatives (such as L-menthone glycerol ketal), 2,3-dimethyl-2-(2-propyl)-butyric acid derivatives (such as 2,3-dimethyl-2-(2-propyl)-butyric acid-N-methylamide [WS23]), isopulegol or its esters (I-(-)-isopulegol, I-(-)-isopulegol acetate), menthane derivatives (such as p-menthane-3,8-diol), cubebol or synthetic or natural mixtures containing cubebol, pyrrolidone derivatives of cycloalkyl dione derivatives (such as 3-methyl-2(1-pyrrolidinyl)-2-cyclopenten-1-one) or tetrahydropyrimidin-2-one (such as icilin or related compounds), additional carboxamides (such as N-(2-(165amascen-2-yl)ethyl)-3-p-menthanecarboxamide or related compounds), (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(1-isopropyl) cyclohexanecarboxamide [WS12], oxalate and [(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl] 2-(ethylamino)-2-oxo-acetate (X-cooling). Coolants preferred due to their special synergistic effects are l-menthol, d-menthol, racemic menthol, menthone glycerol acetal (trade name: MGA), menthyl lactate (preferably l-menthyl lactate, especially l-lactic acid l-menthyl ester (trade name: ML)), substituted menthyl-3-carboxamide (such as menthyl-3-carboxylic acid N-ethylamide), 2-isopropyl-N-2,3-trimethylbutyramide, substituted cyclohexanecarboxamide, 3-menthoxypropane-1,2-diol, 2-hydroxyethyl menthyl carbonate, 2-hydroxypropyl menthyl carbonate and isopulegol. Particularly preferred coolants are l-menthol, racemic menthol, menthone glycerol acetal (trade name: MGA), menthyl lactate (preferably l-menthyl lactate, especially l-lactic acid l-menthyl ester (trade name: ML)), 3-menthoxypropane-1,2-diol, 2-hydroxyethyl menthyl carbonate and 2-hydroxypropyl menthyl carbonate. Highly particularly preferred cooling agents are l-menthol, menthone glycerol acetal (trade name: MGA) and menthyl lactate (preferably l-menthyl lactate, especially l-lactic acid l-menthyl ester (trade name: ML)).

[1093] Alkanediols: In another preferred variant, the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention comprises one or more straight-chain alkanediols having a carbon chain of 5 to 12 carbon atoms. Preferably, the one or more straight-chain alkanediols are selected from the group consisting of: 1,2-alkanediol, 2,3-alkanediol, 3,4-alkanediol and 1,3-alkanediol, more preferably 2,3-alkanediol and 1,3-alkanediol. Most preferably, the straight-chain alkanediol is selected from the group consisting of: 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol and 2,3-dodecanediol.

[1094] The inventors' initial observations surprisingly showed that compositions according to the invention comprising one or more straight-chain alkanediols (preferably as defined herein) having a carbon chain of 5 to 12 carbon atoms exhibit particularly advantageous emulsifying properties. In particular, it was surprisingly found that one or more of said straight-chain alkanediols (in cases where it is not the emulsion itself) support the formation of water or oil droplets having a particularly small average size in the emulsion, or (in the case of the emulsion itself) contain water or droplets having a particularly small average size.

[1095] Furthermore, it was found that the presence of alkanediols (especially 1,2-alkanediol or 2,3-alkanediol) increases the solubility of the oil component (such as one or more oil bodies or waxes) in the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention. Preferably, the oil body or wax is selected from the group consisting of natural fats and oils, fatty alcohols and alcohols, glycerides and their derivatives, esters, ethers, siloxanes and silanes, waxes and cycloalkanes, preferably selected from the group consisting of squalene, dialkylcyclohexane, tetradecane, isocetane, dodecane, docosane, paraffin and mineral oil, and is further described below.

[1096] The combination of one or more of said alkanediols with 4-hydroxyacetophenone generally increases the solubility of the oil component in a synergistic manner in an amount of 0.1% to 2% by weight, more preferably 0.1% to 1% by weight.

[1097] Preferably, based on the total weight of the composition, the composition comprises 0.01% to 10% by weight, more preferably 0.1% to 5% by weight, still more preferably 0.3% to 3% by weight, most preferably 0.5% to 1% by weight of the straight-chain alkanediol having a carbon chain of 5 to 12 carbon atoms as defined herein.

[1098] Antioxidants: The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the invention advantageously comprises one or more antioxidants. Suitable antioxidants include amino acids (preferably glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (preferably urocanic acid) and their derivatives, peptides (preferably D,L-carnosine, D-carnosine, L-carnosine and their derivatives (preferably anserine), carnitine, creatine, matrix factor peptides (preferably lysyl-threonyl-threonyl-lysyl-serine) and palmitoylated pentapeptides, carotenoids, carotenes (preferably α-carotene, β-carotene, lycopene) and their derivatives, lipoic acid and its derivatives (preferably dihydrolipoic acid), glucosinolates, propylthiouracil and other thiols (preferably thioredoxin, glutathione, cysteine, cystine, cystamine and glycosyl, N-acetyl, methyl, ethyl, propyl, pentyl, butyl and lauryl, palmitoyl, oleyl, γ-linolenyl, cholesteryl, glyceryl and their oligoglycerol esters) and their salts, dilauryl thiodipropionate, dilauryl thiodipropionate, dilauryl thiodipropionate, thiodipropionic acid and their derivatives (preferably esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) and sulfoximine compounds (preferably buthionine sulfoximine, homocysteine sulfoximine, buthionine sulfone, penithione sulfone, hexithione sulfone, heptathionine sulfoximine), and (metal) chelating agents (preferably α-hydroxy fatty acids, palmitic acid, phytic acid, lactoferrin, α-hydroxy acids (preferably citric acid, lactic acid, malic acid) humic acid, bile acids, bile extracts, tannins, bilirubin, biliverdin, EDTA, EGTA and their derivatives), unsaturated fatty acids and their derivatives (preferably γ-linolenic acid, linoleic acid, oleic acid), folic acid and its derivatives, ubiquinone and its derivatives, panthenol and its derivatives, vitamin C and its derivatives (preferably ascorbyl palmitate, Mg ascorbyl phosphate, ascorbyl acetate, ascorbyl glucoside), tocopherols and their derivatives (preferably vitamin E acetate), vitamin A and its derivatives (vitamin A palmitate) and coniferyl benzoate, rutinic acid and its derivatives, flavonoids and their glycosylated precursors, especially quercetin and its derivatives, preferably α-glucosylrutin, rosmarinic acid, carnosol, carnosic acid, resveratrol, caffeic acid and its derivatives, sinapic acid and its derivatives, ferulic acid and its derivatives, curcuminoids, chlorogenic acid and its derivatives, retinoids,Preferably, retinol palmitate, retinol or retinoic acid, ursolic acid, levulinic acid, butylated hydroxytoluene, butylated hydroxyanisole, nordihydroguaiaretic acid, nordihydroguaiaretic acid, trihydroxybutanone, uric acid and its derivatives, mannose and its derivatives, zinc and its derivatives (preferably ZnO, ZnSO4), selenium and its derivatives (preferably selenomethionine), superoxide dismutase, stilbene and its derivatives (preferably oxidized stilbene, trans-oxidized stilbene) and derivatives (salts, esters, ethers, sugars, nucleotides, nucleosides, peptides and lipids) of these cited active ingredients suitable according to the present invention or extracts or fractions of plants having an antioxidant effect, preferably green tea, red leaf tea plant, honeybush, grape, rosemary, sage, bee balm, thyme, lavender, olive, oat, cocoa, ginkgo, ginseng, licorice, honeysuckle, sophora, 168amascen, pine, citrus, phyllanthus emblica or St. John's wort, grape seed, wheat germ, phyllanthus emblica, coenzymes, preferably coenzyme Q10, plastoquinone and menaquinone. Preferred antioxidants are selected from the group consisting of: vitamin A and derivatives, vitamin C and derivatives, tocopherols and derivatives, preferably tocopheryl acetate and ubiquinone.

[1099] Emulsifiers: Additionally, the sunscreen product, cosmetic or pharmaceutical preparation or household care product according to the present invention may also advantageously contain one or more emulsifiers to maintain the stability of the sunscreen product, cosmetic or pharmaceutical preparation or household care product. Emulsifiers include amphoteric, anionic, cationic or nonionic emulsifiers that can be used alone or in combination. The emulsifier is selected in a suitable manner according to the emulsion to be obtained. Preferred examples include:

[1100] - Products obtained by adding 2 mol to 30 mol of ethylene oxide and / or 0 mol to 5 mol of propylene oxide to linear C 8-22 fatty alcohols, C 12-22 fatty acids and alkylphenols having 8 to 15 carbon atoms in the alkyl group;

[1101] - C 12 / 18 fatty acid monoesters and diesters of products obtained by adding 1 mol to 30 mol of ethylene oxide to glycerol;

[1102] - Glycerol monoesters and diesters, sorbitol monoesters and diesters of saturated and unsaturated fatty acids having 6 to 22 carbon atoms and their ethylene oxide adducts;

[1103] - Products obtained by adding 15 mol to 60 mol of ethylene oxide to castor oil and / or hydrogenated castor oil;

[1104] - Polyol esters, and especially polyglycerol esters, such as, for example, polyglycerol polyricinoleate, polyglycerol poly-12-hydroxystearate or polyglycerol dimethyl isostearate. Mixtures of compounds from several of these classes are also suitable;

[1105] - A product obtained by adding 2 to 15 moles of ethylene oxide to castor oil and / or hydrogenated castor oil;

[1106] - Based on linear, branched, unsaturated or saturated C 6 / 22 fatty acids, ricinoleic acid and 12 - hydroxystearic acid and glycerol, polyglycerol, pentaerythritol, dipentaerythritol, sugar alcohols (such as sorbitol), alkyl glucosides (such as methyl glucoside, butyl glucoside, lauryl glucoside) and polyglucosides (such as cellulose);

[1107] - Monoalkyl phosphates, dialkyl phosphates and trialkyl phosphates and mono - PEG - alkyl phosphates, di - PEG - alkyl phosphates and / or tri - PEG - alkyl phosphates and their salts;

[1108] - Lanolin alcohol;

[1109] - Polysiloxane / polyalkyl polyether copolymers and corresponding derivatives;

[1110] - Mixed esters of pentaerythritol, fatty acids, citric acid and fatty alcohols and / or C 6-22 Mixed esters of fatty acids, methyl glucose and polyols, preferably glycerol or polyglycerol,

[1111] - Polyalkylene glycols and

[1112] - Glycerol carbonate.

[1113] Products obtained by adding ethylene oxide and / or propylene oxide to fatty alcohols, fatty acids, alkylphenols, glycerol monoesters and diesters of fatty acids and sorbitan monoesters and diesters or to castor oil are known commercially available products. They are mixtures of homologues, the average degree of alkoxylation of which corresponds to the ratio between the amount of ethylene oxide and / or propylene oxide and the substrate to which the addition reaction is carried out. The C 12 / 18 fatty acid monoesters and diesters of the addition product of ethylene oxide on glycerol are known as lipid layer enhancers in cosmetic formulations. The preferred emulsifiers are described in more detail below:

[1114] Partial glycerides: Typical examples of suitable partial glycerides are monoglyceryl hydroxystearate, diglyceryl hydroxystearate, monoglyceryl isostearate, diglyceryl isostearate, monoglyceryl oleate, diglyceryl oleate, monoglyceryl ricinoleate, diglyceryl ricinoleate, monoglyceryl linoleate, diglyceryl linoleate, monoglyceryl linolenate, diglyceryl linolenate, monoglyceryl erucate, diglyceryl erucate, monoglyceryl tartrate, diglyceryl tartrate, monoglyceryl citrate, diglyceryl citrate, monoglyceryl malate, diglyceryl malate and their industrial mixtures, which may still contain small amounts of triglycerides from the production process. Also suitable are products obtained by adding 1 to 30 and preferably 5 mol to 10 mol of ethylene oxide to the partial glycerides mentioned.

[1115] Sorbitan esters: Suitable sorbitan esters are sorbitan monoisostearate, sorbitan sesquiisostearate, sorbitan diisostearate, sorbitan triisostearate, sorbitan monooleate, sorbitan sesquioleate, sorbitan dioleate, sorbitan trioleate, sorbitan monoricinoleate, sorbitan sesquiricinoleate, sorbitan diricinoleate, sorbitan triricinoleate, sorbitan monohydroxystearate, sorbitan sesquihydroxystearate, sorbitan dihydroxystearate 170amascene170, sorbitan trihydroxystearate, sorbitan monotartrate, sorbitan sesquitartrate, sorbitan ditartrate, sorbitan tritartrate, sorbitan monocitrate, sorbitan sesquicitrate, sorbitan dicitrate, sorbitan tricitrate, sorbitan monomaleate, sorbitan sesquimaleate, sorbitan dimaleate, sorbitan trimaleate and their technical mixtures. Also suitable are products obtained by adding 1 to 30 and preferably 5 mol to 10 mol of ethylene oxide to the sorbitan esters mentioned.

[1116] Polyglycerol esters: Typical examples of suitable polyglycerol esters are polyglycerol-2 dimer hydroxystearate ( PGPH), polyglycerol-3 diisostearate ( TGI), polyglycerol-4 isostearate ( GI 34), polyglycerol-3 oleate, polyglycerol diisostearyl-3 diisostearate ( PDI), polyglycerol-3 methylglucose distearate (Tego 450), polyglycerol-3 beeswax (Cera ) Polyglyceryl-4 decanoate (polyglyceryl decanoate T2010 / 90), polyglyceryl-3 cetyl ether ( NL), polyglyceryl-3 distearate ( GS 32) and polyglyceryl polyricinoleate ( WOL 1403), polyglyceryl dimethyl ether isostearate and mixtures thereof. Examples of other suitable polyol esters are mono-, di- and triesters of trimethylolpropane or pentaerythritol with lauric acid, coconut fatty acids, tallow fatty acids, palmitic acid, stearic acid, oleic acid, behenic acid, etc., optionally reacted with 1 mol to 30 mol of ethylene oxide.

[1117] Anionic emulsifiers: Typical anionic emulsifiers are aliphatic C12 to C22 fatty acids (such as, for example, palmitic acid, stearic acid or behenic acid), and C12 to C22 dicarboxylic acids (such as, for example, azelaic acid or sebacic acid), potassium cetyl phosphate and hydrogenated palm glycerides (Emulsiphos / Emulsiphos F).

[1118] Amphoteric emulsifiers: Other suitable emulsifiers are amphoteric or zwitterionic surfactants. Zwitterionic surfactants are surface-active compounds that contain at least one quaternary ammonium group and at least one carboxylate and one sulfonate group in the molecule. Particularly suitable zwitterionic surfactants are the so-called betaines, such as N-alkyl-N,N-dimethylammonium glycine, for example cocoalkyl dimethylammonium glycinate, N-acylaminopropyl-N,N-dimethylammonium glycine, for example cocoacylaminopropyl dimethylammonium glycinate and 2-alkyl-3-carboxymethyl-3-hydroxyethylimidazoline and cocoacylamidoethyl hydroxyethyl carboxymethyl glycinate containing 8 to 18 carbon atoms in the alkyl or acyl group. Particularly preferred is the known fatty acid amide derivative CTFA named cocoamidopropyl betaine. Amphoteric surfactants are also suitable emulsifiers. Amphoteric surfactants are surface-active compounds that contain at least one free amino group and at least one -COOH- or -SO3H- group in the molecule in addition to the C 8 / 18 alkyl or acyl group and are capable of forming an internal salt. Examples of suitable amphoteric surfactants are N-alkyl glycine, N-alkyl propionic acid, N-alkyl aminobutyric acid, N-alkyliminodipropionic acid, N-hydroxyethyl-N-alkylaminopropyl glycine, N-alkyl taurine, N-alkyl sarcosine, 2-alkylaminopropionic acid and alkylaminoacetic acid, the alkyl group of which contains about 8 to 18 carbon atoms. Particularly preferred amphoteric surfactants are N-cocoalkyl aminopropionate, cocoacylaminoethyl aminopropionate and C 12 / 18 acyl sarcosine.

[1119] Anti-aging active substances: The composition according to the invention is preferably combined with one or more anti-aging active substances. In the context of the present invention, anti-aging agents or biogenic agents are, for example, antioxidants, matrix metalloproteinase inhibitors (MMPIs), skin moisturizers, glycosaminoglycan stimulants, anti-inflammatory agents, TRPV1 antagonists, and plant extracts.

[1120] Matrix metalloproteinase inhibitors (MMPIs): The composition according to the invention is preferably combined with one or more matrix metalloproteinase inhibitors, in particular those that inhibit the enzymatic cleavage of collagen by matrix metalloproteinases, and these inhibitors are selected from the group consisting of: ursolic acid, retinol palmitate, propyl gallate, noren, 6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran, 3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran, benzamidine hydrochloride, cysteine protease inhibitor N-ethylmaleimide, and serine protease inhibitors of ε-amino-N-caproic acid: phenylmethylsulfonyl fluoride, collhibin (Pentapharm; INCI: hydrolyzed rice protein), oenotherol (Soliance; INCI: propylene glycol, aqueous, evening primrose root extract, ellagic acid, and ellagitannins, such as from pomegranate), phomopsin A, EDTA, MGDA (trisodium dicarboxymethylalanine), galardin, EquiStat (Collaborative Group; apple fruit extract, soybean seed extract, ursolic acid, soy isoflavones, and soy protein), sage extract, MDI (Atrium; INCI: glycosaminoglycan), fermiskin (Silab / Mawi; INCI: water and shiitake mushroom extract), actimp 1.9.3 (Expanscience / Rahn; INCI: hydrolyzed lupine protein), soy isoflavones (company Mibelle; INCI: ethanol, polysorbate 80, lecithin, and soy isoflavones), green and black tea extracts, and other plant extracts, proteins or glycoproteins from soy, hydrolyzed proteins from rice, peas, or lupine, plant extracts that inhibit MMPs, preferably extracts from shiitake mushrooms, extracts from the leaves of the Rosoideae subfamily of Rosaceae, especially extracts from blackberry leaves, such as, for example, SymMatrix (Symrise; INCI: maltodextrin, redberry (blackberry) leaf extract). Preferred active ingredients are selected from the group consisting of: retinol palmitate, ursolic acid, extracts from the leaves of the Rosoideae subfamily of Rosaceae, genistein, and daidzein.

[1121] Skin moisturizing substances and / or water-retaining substances: The sunscreen product or cosmetic or pharmaceutical preparation according to the invention advantageously comprises one or more skin moisturizing substances and / or water-retaining substances. Preferred skin moisturizing substances and / or water-retaining substances are selected from the group consisting of alkanediols or alkanetriols having from 3 to 12 carbon atoms, preferably C3-C 10 -alkanediols and C3-C 10 -alkanetriols. More preferably, the skin moisturizer is selected from the group consisting of: glycerol, 1,2-propanediol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol and 1,2-decanediol. Additional skin moisturizing substances and / or water-retaining substances include sodium lactate, urea, urea derivatives, alcohols, glycerol, diols (such as propylene glycol, hexylene glycol), collagen, elastin or hyaluronic acid, diacyl adipates, petrolatum, urocanic acid, lecithin, panthenol, phytantriol, lycopene, (pseudo)ceramides, glycosphingolipids, cholesterol, phytosterols, chitosan, chondroitin sulfate, lanolin, lanolin esters, amino acids, α-hydroxy acids (such as citric acid, lactic acid, malic acid) and their derivatives, monosaccharides, disaccharides and oligosaccharides (such as glucose, galactose, fructose, mannose, fructose and lactose), polysaccharides (such as R-glucan), especially 1,3-1,4-β-glucan from oats, α-hydroxy fatty acids, triterpenic acids (such as betulinic acid or ursolic acid) and algae extracts.

[1122] Glycosaminoglycan stimulant: Preferred compositions according to the invention comprise one or more substances that stimulate glycosaminoglycan synthesis, which substances are selected from the group consisting of: hyaluronic acid and its derivatives or salts, Subliskin (Sederma, INCI: Medicago sativa root extract fermentate filtrate, cetyl hydroxyethylcellulose, lecithin), Hyalufix (BASF, INCI: water, butylene glycol, Alpinia officinarum leaf extract, xanthan gum, caprylic / capric triglyceride), Stimulhyal (Soliance, INCI: calcium ketogluconate), Syn-Glycan (DSM, INCI: tetradecylaminobutyroylvalylaminobutyramide trifluoroacetate, glycerol, magnesium chloride), Kalpariane (Biotech Marine), DC Upregulex (Distinctive Cosmetic Ingredients, INCI: water, butylene glycol, phospholipids, hydrolyzed sericin), glucosamine, N-acetylglucosamine, retinoids, preferably retinol and vitamin A, Arctium lappa fruit extract, Eriobotrya japonica extract, genkwanin, N-methyl-L-serine, (-)-α-bisabolol or synthetic α-bisabolol, such as, for example, Dragosantol and Dragosantol 100 from Symrise, oat beta-glucan, Echinacea purpurea extract and soy protein hydrolysate. Preferred active substances are selected from the group consisting of: hyaluronic acid and its derivatives or salts, (-)-α-bisabolol or synthetic α-bisabolol, such as, for example, Dragosantol and Dragosantol 100 from Symrise, oat beta-glucan, Echinacea purpurea extract, Medicago sativa root extract fermentate filtrate, calcium ketogluconate, Alpinia officinarum leaf extract and tetradecylaminobutyroylvalylaminobutyramide trifluoroacetate.

[1123] Anti-inflammatory agent: The compositions according to the invention are preferably combined with anti-inflammatory and / or redness- and / or itching-improving ingredients. In particular, steroid substances selected from the group consisting of hydrocortisone, dexamethasone, dexamethasone phosphate, methylprednisolone or cortisone are advantageously used as anti-inflammatory active ingredients or active ingredients for reducing redness and itching, and the list thereof can be extended by adding other steroidal anti-inflammatory drugs. Non-steroidal anti-inflammatory drugs can also be used. More specifically:

[1124] (i) Steroidal anti-inflammatory substances of the corticosteroid type, in particular hydrocortisone, hydrocortisone derivatives such as hydrocortisone 17-butyrate, dexamethasone, dexamethasone phosphate, methylprednisolone or cortisone,

[1125] (ii) Non-steroidal anti-inflammatory substances, especially oxicams (such as piroxicam or tenoxicam), salicylates (such as aspirin, disalci...

Claims

1. A sunscreen product, a cosmetic or a pharmaceutical preparation or a household care product, said sunscreen product, cosmetic or pharmaceutical preparation or household care product comprising or consisting of the following: (a) At least one major organic and / or inorganic UV filter; (b) At least one mycosporine-like amino acid compound, said at least one mycosporine-like amino acid compound being represented by the general formula (V) wherein -Z is selected from the group consisting of O-R2' or amide'; -R1' is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted C(alkyl)2, unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), CR7'R8', C═O, halogen, O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl) and unsubstituted or substituted N(heteroaryl) and unsubstituted or substituted C-spiro ring; -R2' is selected from the group consisting of: H, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl; -amide' is selected from the group consisting of: NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl) and unsubstituted or substituted NR9'R10', unsubstituted or substituted -N(O-alkyl)(alkyl)(Weinreb amide), -N(OH)(H)(isohydroxamic acid) and unsubstituted or substituted -N(OH)(alkyl)(alkylated isohydroxamic acid); - R3' is selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9'R10' and unsubstituted or substituted C-spiro; - The substituents R4', R5' and R6', which can be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, -S(=O)2OH, sulfonyl, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl) and unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9'R10' and unsubstituted or substituted C-spiro; - R7' and R8', which may be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), and unsubstituted or substituted NR9'R10'; - R9' and R10', which may be the same or different, are each independently selected from the group consisting of: H, OH, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, and unsubstituted or substituted heteroaryl; - Y is selected from the group consisting of H and unsubstituted or substituted alkyl; and - R is unsubstituted alkyl or substituted alkyl; or a tautomer, stereoisomer or salt of the above compound; or represented by the general formula (VI) wherein - R1” is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted C(alkyl)2, unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), -CR7”R8”, C=O, halogen, O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl), unsubstituted or substituted N(heteroaryl), and unsubstituted or substituted C-spiro ring; -R2” is selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH-C(=O)-O-Y, -C(=O)-amide”, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9”R10” and unsubstituted or substituted C-spiro; -X is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted CH(alkenyl), unsubstituted or substituted CH(alkynyl), unsubstituted or substituted CH(alkoxy), unsubstituted or substituted CH(alkylthio), unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), -CR7”R8”, C=O, O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl), unsubstituted or substituted N(heteroaryl) and unsubstituted or substituted C-spiro; - The substituents R4″, R5″, and R6″, which can be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, -S(=O)2OH, sulfonyl, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), and unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9″R10″, and unsubstituted or substituted C-spiro ring; - The R7″ and R8″, which can be the same or different, are each independently selected from the group consisting of: H, OH, halogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, -CH2-OH, -R-CH2-OH, -C(=O)-O-Y, -R-C(=O)-O-Y, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted heteroaryl, SO, SO2, NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), and unsubstituted or substituted NR9″R10″; -amide” is selected from the group consisting of: NH2, unsubstituted or substituted NH(alkyl), unsubstituted or substituted NH(alkenyl), unsubstituted or substituted NH(alkynyl), unsubstituted or substituted NH(alkoxy), unsubstituted or substituted NH(alkylthio), unsubstituted or substituted NH(cycloalkyl), unsubstituted or substituted NH(aryl), unsubstituted or substituted NH(heterocycloalkyl), unsubstituted or substituted NH(heteroaryl), unsubstituted or substituted NR9”R10”, unsubstituted or substituted -N(O-alkyl)(alkyl)(Weinreb amide), -N(OH)(H)(isohydroxamic acid), and unsubstituted or substituted -N(OH)(alkyl)(alkylated isohydroxamic acid); -R9” and R10”, which can be the same or different, are each independently selected from the group consisting of: H, OH, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted alkoxy, unsubstituted or substituted alkylthio, unsubstituted or substituted alkanoyl / acyl R-C(=O)-, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocycloalkyl, and unsubstituted or substituted heteroaryl; -Y is selected from the group consisting of H and unsubstituted or substituted alkyl; and -R is unsubstituted alkyl or substituted alkyl; or a tautomer or stereoisomer or salt of the above compound; or any mixture of the above compounds; and (c) optionally at least one film-forming agent; provided that the following compounds are rejected / excluded: Compound 1: Compound 2: Compound 3: Compound 4: Compound 5: Compound 6: Compound 7: Compound 8:

2. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to claim 1, wherein the mycosporine-like amino acid compound (b) is represented by the general formula (VII) wherein R1', R2', R3', R4', R5' and R6' have the same meanings as defined in formula (V); or is represented by the general formula (VIII) wherein R1', amide', R3', R4', R5' and R6' have the same meanings as defined in formula (V).

3. The sunscreen product, cosmetic, pharmaceutical preparation or household care product according to claim 1 or claim 2, wherein in the general formula (VI), X is selected from the group consisting of: CH2, unsubstituted or substituted CH(alkyl), unsubstituted or substituted C(alkyl)2, unsubstituted or substituted CH(alkenyl), unsubstituted or substituted CH(alkynyl), unsubstituted or substituted CH(alkoxy), unsubstituted or substituted CH(alkylthio), unsubstituted or substituted CH(cycloalkyl), unsubstituted or substituted CH(aryl), unsubstituted or substituted CH(heterocycloalkyl), unsubstituted or substituted CH(heteroaryl), -CR7”R8”, C=O, S, SO, SO2, NH, unsubstituted or substituted N(alkyl), unsubstituted or substituted N(alkenyl), unsubstituted or substituted N(alkynyl), unsubstituted or substituted N(alkoxy), unsubstituted or substituted N(alkylthio), unsubstituted or substituted N(cycloalkyl), unsubstituted or substituted N(aryl), unsubstituted or substituted N(heterocycloalkyl), unsubstituted or substituted N(heteroaryl) and unsubstituted or substituted C-spiro ring.

4. The sunscreen product, cosmetic, pharmaceutical preparation or household care product according to any one of claims 1 to 3, wherein in the general formula (V), -Z is -O-R2' or amide'; and / or -R1' is selected from the group consisting of: CH2, C(alkyl)2, O, S, SO, SO2, NH and N(alkyl); and / or -R2' is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethylhexyl) and phenyl; or -amide' is selected from the group consisting of: NH2, NH(alkyl) and N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide) and -N(OH)(H) (isohydroxamic acid); and / or -R3' is selected from the group consisting of: H, methyl, ethyl, -O-methyl, -C(=O)-OH, -C(=O)-CH3, -C(=O)-C3H7 and -C(=O)-O-methyl; and / or - the substituents R4', R5' and R6' have the same meanings as defined in formula (V); - wherein alkyl is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl; or wherein in the general formula (VII) or (VIII), -R1' is selected from the group consisting of: CH2, C(alkyl)2, O, S, SO, SO2, NH and N(alkyl); and / or -R2' is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethylhexyl) and phenyl; or -amide' is selected from the group consisting of: NH2, NH(alkyl) and N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide) and -N(OH)(H) (isohydroxamic acid); and / or - R3' is selected from the group consisting of: H, methyl, ethyl, -O-methyl, -C(=O)-OH, -C(=O)-CH3, -C(=O)-C3H7, and -C(=O)-O-methyl; and / or - the substituents R4', R5', and R6' have the same meanings as defined in formulas (VII) and (VIII); - wherein the alkyl group is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl; or wherein in the general formula (VI), - R1” is selected from the group consisting of: CH2, C(alkyl)2, O, S, SO, SO2, NH, and N(alkyl); and / or - R2” is selected from the group consisting of: -CH2-OH, -C(=O)-O-Y, and -C(=O)-amide”; and / or - X is selected from the group consisting of: CH2, C=O, O, S, SO, SO2, NH, and N(alkyl); and / or -Y is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethylhexyl) and phenyl; and / or - amide” is selected from the group consisting of: NH2, NH(alkyl), and N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide), and -N(OH)(H) (isohydroxamic acid); and / or - the substituents R4”, R5”, and R6” have the same meanings as defined in formula (VI); - wherein the alkyl group is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl.

5. The sunscreen product, cosmetic or pharmaceutical preparation, or household care product according to any one of claims 1 to 4, wherein in the general formula (V), - Z is -O-R2' or amide'; and / or - R1' is selected from the group consisting of CH2 and C(methyl)2; and / or -R2' is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethylhexyl) and phenyl; or - amide' is selected from the group consisting of: NH2, NH(alkyl), and N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide), and -N(OH)(H) (isohydroxamic acid); and / or - R3' is selected from the group consisting of: H, methyl, ethyl, -O-methyl, -C(=O)-OH, -C(=O)-CH3, -C(=O)-C3H7, and -C(=O)-O-methyl; and / or - the substituents R4', R5', and R6' have the same meanings as defined in formula (V); - wherein the alkyl group is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, and tert-butyl; or wherein in the general formula (VII) or (VIII), - R1' is selected from the group consisting of CH2 and C(methyl)2; -R2' is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethylhexyl) and phenyl; or - amide' is selected from the group consisting of: NH2, NH(alkyl), and N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide), and -N(OH)(H) (isohydroxamic acid); and / or - R3' is selected from the group consisting of: H, methyl, ethyl, -O-methyl, -C(=O)-OH, -C(=O)-CH3, -C(=O)-C3H7, and -C(=O)-O-methyl; and / or - The substituents R4', R5' and R6' have the same meanings as defined in formulas (VII) and (VIII); - wherein the alkyl group is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl; and / or or wherein in the general formula (VI), - R1” is selected from the group consisting of CH2 and C(methyl)2; and / or - R2” is selected from the group consisting of: -CH2-OH, -C(=O)-O-Y and -C(=O)-amide”; and / or - X is selected from the group consisting of: CH2, C=O, O, S, SO, SO2, NH and N(alkyl); and / or -Y is selected from the group consisting of: H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, (2-ethylhexyl) and phenyl; and / or - amide” is selected from the group consisting of: NH2, NH(alkyl) and N(alkyl)2, -N(O-alkyl)(alkyl) (Weinreb amide) and -N(OH)(H) (hydroxamic acid); and / or - The substituents R4”, R5” and R6” have the same meanings as defined in formula (VI); - wherein the alkyl group is selected from the group consisting of: methyl, ethyl, propyl, isopropyl, butyl, isobutyl and tert-butyl.

6. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 5, wherein the mycosporine-like amino acid compound (b) is selected from the group consisting of the following compounds I-1 to I-128 according to the general formula (V) and the following compounds II-1 to II-192 according to the general formula (VI): wherein in the above mycosporine-like amino acid compound, the benzene ring can be unsubstituted or substituted, and R4', R5', R6', R4”, R5”, R6”, amide', Y, amide” and alkyl have the same meanings as defined in any one of the foregoing claims, or tautomeric forms or stereoisomers or salts of the above compounds; or wherein the mycosporine-like amino acid compound is selected from the group consisting of: MAA-A: MAA-B: and MAA-C: wherein the alkyl group is methyl or ethyl or propyl or butyl, preferably methyl, or tautomeric forms or salts of the above compounds; or any mixture of the above compounds.

7. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 6, wherein in the general formulas (VI), (IX) and (X), X is S, SO or SO2, and / or wherein in the general formulas (V) to (X), n = 1.

8. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 7, wherein in the general formulas (V), (VII) and (VIII), the substituents R4', R5' and R6', which can be the same or different, are independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl or tert-butyl, alkoxy, preferably O-methyl, O-ethyl or O-butyl, -S(=O)2OH and sulfonyl; Or In the general formulas (VI), (IX) and (X), the substituents R4″, R5″ and R6″, which may be the same or different, are each independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl or tert-butyl, alkoxy, preferably O-methyl, O-ethyl or O-butyl, -S(=O)2OH and sulfonyl groups.

9. A sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 8, wherein in the general formulas (V) to (X), the substituted phenyl group bonded to the imino functional group is selected from the group consisting of: wherein the dashed line represents the binding site.

10. A sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 9, wherein in the general formulas (V), (VII) and (VIII), the substituents R4′, R5′, R6′, which may be the same or different, are each independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl or tert-butyl, alkoxy, preferably O-methyl, O-ethyl or O-butyl, -S(=O)2OH and sulfonyl groups; provided that if the substituted benzene ring is monosubstituted, the substituent is in the ortho or meta position to the imino functional group; or wherein in the general formulas (VI), (IX) and (X), the substituents R4″, R5″, R6″, which may be the same or different, are each independently selected from the group consisting of: H, OH, alkyl, preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl or tert-butyl, alkoxy, preferably O-methyl, O-ethyl or O-butyl, -S(=O)2OH and sulfonyl groups; provided that if the substituted benzene ring is monosubstituted, the substituent is in the ortho or meta position to the imino functional group.

11. A sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 10, wherein the mycosporine-like amino acid compound (b) is selected from the group consisting of: or a tautomer or stereoisomer or salt of the above compound; or any mixture of the above compounds.

12. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 11, wherein the at least one main organic and / or inorganic UV filter (a) is selected from the group consisting of: camphor benzalkonium methyl sulfate, homosalate, benzophenone-3, phenylbenzimidazole sulfonic acid, terephthalylidene dicamphor sulfonic acid, butyl methoxydibenzoylmethane, benzylidene camphor sulfonic acid, octocrylene, polyacrylamidomethyl benzylidene camphor, ethylhexyl methoxycinnamate, PEG-25 PABA, isoamyl p-methoxycinnamate, ethylhexyl triazone, cresol triazone, diethylhexyl butamido triazone, 4-methylbenzylidene camphor, ethylhexyl salicylate, diethylhexyl PABA, benzophenone-4, benzophenone-5, methylene bis-benzotriazolyl tetramethylbutylphenol (nano), diphenyl dibenzimidazole tetrasulfonate disodium, bis-ethylhexyloxyphenol methoxyphenyl triazine, polysiloxane-15, titanium dioxide, titanium dioxide (nano), diethylamino hydroxybenzoyl hexyl benzoate, triphenyl triazine (nano), zinc oxide, zinc oxide (nano), phenyl bis-diphenyl triazine, methoxypropylamino cyclohexenyl ethoxyethyl cyanoacetate, bis-(diethylamino hydroxybenzoyl benzoyl) piperazine, TEA-salicylate, benzophenone-8, PABA, diethylhexyl PABA, menthyl anthranilate and any mixture thereof.

13. A sunscreen product, cosmetic, pharmaceutical preparation or household care product according to any one of claims 1 to 12, wherein the at least one film-forming agent (c) is selected from the group consisting of: polyamide-8 (such as Oleocraft LP 20PA (MV)), polyamide-3 (such as Oleocraft MP 30PA (MV)), trimethylolpropane / adipic acid / glycerol crosslinked polymer (such as wet film), octyldodecyl citrate crosslinked polymer (such as CosmoSurf CE 100), polyglyceryl-3 methylglucose distearate (such as TegoCare 450), C28-52 olefin / undecenoic acid copolymer (such as PerformaV6112), hydrolyzed jojoba esters, jojoba esters, aqueous agents (such as Floraester jojoba K100), cyclopentasiloxane acrylate / dimethicone copolymer (such as KP545), acrylate / behenyl polyether-25 methacrylate copolymer (such as Volarest), styrene / acrylate copolymer (such as Dermacryl E polymer), polyurethane (such as Baycusan C1001), polyurethane-2 and polymethyl methacrylate (such as Hybridur875 polymer), acrylate / octylacrylamide copolymer (such as Dermacryl 2.0 polymer), beeswax (white beeswax) (and) sodium stearoyl lactylate (such as SymEffektSun), amylopectin, xanthan gum, hydrogenated palm oil, sugarcane extract (SymEffect TM UV), microcrystalline cellulose (and) Sphingomonas fermentation extract (and) cellulose gum (such as PemuPur TM START polymer), gum arabic and xanthan gum (such as SOLAGUM TM AX), microcrystalline cellulose (and) cellulose gum (such as Natpure Cellgum enhanced), sodium stearoyl glutamate (such as HS-11P), hydrogenated polycyclopentadiene (and) caprylic / capric triglyceride (such as 5400CCT), glycerol hydrogenated abietate (and) caprylic / capric triglyceride (and) tocopherol (such as NATURAL 2063-CCT), galactoarabinan (such as A 200), C26-28 alkyl dimethicone (such as Wacker CDM 3526VP), octanoyl methylsiloxane (such as Silsoft034), stearyl dimethicone (and) 1-octadecene (such as Dowsil 2503 cosmetic wax), VP / hexadecene copolymer (such as Antaron TM V 216), tricontanyl PVP (such as Antaron TM WP-660), caprylyl glycerol / sebacate copolymer (such as LexFilm TM Sun Natural MB), poly C10-30 alkyl acrylate (such as Tego SP 13 SunUp), microcrystalline cellulose (such as Sunspheres TM BIO SPF enhancer) and any mixtures thereof.

14. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 13, the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprising the at least one main organic and / or inorganic UV filter (a) or a mixture thereof, based on the total weight of the product or preparation, the amount of the at least one main organic and / or inorganic UV filter or a mixture thereof being from 0.01% by weight to 80.0% by weight, in particular from 0.1% by weight to 75.0% by weight, more particularly from 0.5% by weight to 70.0% by weight, most particularly from 1.0% by weight to 60.0% by weight.

15. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 14, the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprising the at least one mycosporine-like amino acid compound (b) or a mixture thereof, based on the total weight of the product or preparation, the amount of the at least one mycosporine-like amino acid compound or a mixture thereof being from 0.001% by weight to 15.0% by weight, in particular from 0.01% by weight to 10.0% by weight, more particularly from 0.05% by weight to 7.5% by weight, most particularly from 0.1% by weight to 5.0% by weight.

16. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 15, wherein the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprises the at least one film-forming agent (c) or a mixture thereof, and based on the total weight of the product or preparation, the amount of the at least one film-forming agent or a mixture thereof is from 0.01% by weight to 10.0% by weight, particularly from 0.05% by weight to 8.0% by weight, and most particularly from 0.1% by weight to 5.0% by weight.

17. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 16, wherein the sunscreen product, cosmetic or pharmaceutical preparation or household care product further comprises at least one 1,2-alkanediol or 2,3-alkanediol having 5 to 12 carbon atoms, wherein the 1,2-alkanediol is preferably selected from the group consisting of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, and wherein the 2,3-alkanediol is selected from the group consisting of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol and any mixture thereof.

18. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 17, wherein the sunscreen product, cosmetic or pharmaceutical preparation or household care product further comprises one or more antimicrobial agents, preferably wherein the antimicrobial agent is selected from the group consisting of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2-benzylheptanol, 2-hydroxyacetophenone, 2-methyl-5-cyclohexylpentanol, 3-hydroxypropyl 2-hydroxybenzoate, 4-hydroxyacetophenone and any mixture thereof.

19. The sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 18, wherein the sunscreen product, cosmetic or pharmaceutical preparation or household care product further comprises at least one excipient and / or cosmetic or pharmaceutical active substance selected from the group consisting of emollients, rheology additives, silicones, dryness modifiers, skin moisturizing substances and / or water retention substances, soothing substances, physiological coolants, antioxidants, emulsifiers, preservatives, fragrances or perfume oils and any mixture of two or more of the above substances.

20. A sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 19, wherein the sunscreen product, cosmetic or pharmaceutical preparation or household care product is in the form of (i) a dispersion, preferably wherein the cosmetic or pharmaceutical preparation is in the form of an emulsion, in particular an O / W emulsion, a W / O emulsion, a multiple emulsion, a hydrodispersion gel, an essential oil, a W / O / W or O / W / O multiple emulsion, a PIT emulsion, a Pickering emulsion, a microemulsion, a liquid, a lotion, a suspension, a milk, an ointment, a paste, a gel, a cream-based, oil-based or liposome-based formulation or an aerosol, in particular a foam and a spray, including all types of silicone-based emulsions; (ii) an anhydrous formulation; or (iii) a solution based on water or water / alcohol, in particular water / ethanol, or water / glycol, or alcohol / glycol, in particular ethanol / glycol.

21. A sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 20, wherein the sunscreen product, cosmetic or pharmaceutical preparation or household care product is used as a cosmetic for personal care, in particular for skin, hair, scalp or nail care, as a pharmaceutical for animal care or as a household care product.

22. A sunscreen product, cosmetic or pharmaceutical preparation or household care product according to any one of claims 1 to 21, wherein the water resistance after immersion in water is increased by at least 5%, preferably by at least 7.5%, more preferably by at least 10% and most preferably by at least 12.5% compared to a sunscreen product, cosmetic or pharmaceutical preparation or household care product without the mycosporine-like amino acid compound (b), as described in the present application.

23. Use of a mycosporine-like amino acid compound or a mixture thereof as defined in any one of claims 1 to 11 for increasing the water resistance of a sunscreen product, cosmetic or pharmaceutical preparation or household care product, the sunscreen product, cosmetic or pharmaceutical preparation or household care product comprising at least one major organic or inorganic UV filter and optionally at least one film-forming agent.

24. A method for improving the water resistance of a sunscreen product, a cosmetic product, a pharmaceutical preparation or a household care product, said sunscreen product, cosmetic product, pharmaceutical preparation or household care product comprising at least one major organic and / or inorganic UV filter and optionally at least one film-forming agent, the method comprising: Adding an effective amount of a mycosporine-like amino acid compound or a mixture thereof as defined in any one of claims 1 to 11 to the sunscreen product, cosmetic or pharmaceutical preparation or household care product.

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