Cell suction device for immune cell detection for nerve infection

By designing a cell aspiration device with an expandable contraction structure and a magnetic suction connection filter, the existing device has solved the problem of inconvenient operation and impurities mixing in detection of nerve-infected immune cells, and achieved rapid and stable cell aspiration and efficient detection.

CN120383989AActive Publication Date: 2025-07-29THE THIRD AFFILIATED HOSPITAL OF PLA NAVAL MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202510884315.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-30
Publication Date
2025-07-29
Estimated Expiration
2045-06-30

AI Technical Summary

Technical Problem

Existing cell aspiration devices are difficult to accurately control cell types and quantities in the detection of nerve-infected immune cells, easily mix impurities, and are inconvenient and unstable in operation, which affects the accuracy and efficiency of the detection results.

Method used

A cell suction device is designed, using a suction tip with an expandable contraction structure, combined with a magnetic suction connection filter structure and an anti-slip jacket to achieve rapid installation and replacement of the suction nozzle, and improve stability by fitting the jacket with a hand grip curve. A built-in replaceable filter is used to filter large cells and bonded twin cells.

Benefits of technology

It realizes rapid and stable absorption of nerve-infected immune cells, improves operation convenience and detection accuracy, reduces impurity interference, and enhances the stability and comfort of the device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a cell suction device for immune cell detection for nerve infection, relates to the technical field of cell suction devices, and provides the following scheme that the cell suction device comprises a suction device, a cell filtering piece is arranged at the front end of the suction device, and an expansion and contraction structure is fixedly connected into an inner cavity of the cell filtering piece. According to the cell suction device provided by the invention, the end of the cell suction device is arranged to be of an expandable and contractible structure, the suction nozzle can be quickly and easily mounted and replaced, meanwhile, the connection firmness between the cell suction device and the suction nozzle is improved, the jacket fitting a hand holding curve is arranged on the periphery of the cell suction device, anti-skid lines are arranged on the periphery of the jacket, and the jacket can be clamped with the wrist, so that the cell suction device is convenient to use. The suction device is prevented from being separated from the hand, and stability is improved. A replaceable filter screen structure is arranged in the suction end, a filter screen is connected through magnetic suction, the filter screen can be of a screen structure or a membrane structure, and the effects of screening out overlarge cells, bonding double cells and even dead cells are achieved.
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Description

Technical Field

[0001] The present invention relates to the technical field of cell aspirators, and particularly relates to a cell aspiration device for immune cell detection for nerve infections. Background Art

[0002] In neuroscience research and clinical diagnosis, the detection and treatment of nerve infection-related diseases have always been important research fields. As an important part of the body's immune system, immune cells play a key role in the process of nerve infection. Changes in their quantity, type, and functional status can reflect the severity and progression of nerve infection. Therefore, accurate and efficient detection of immune cells related to nerve infection is of great significance for early diagnosis of diseases, condition monitoring, and selection of treatment plans. Currently, in the field of immune cell detection, cell aspiration devices are important tools for obtaining cell samples. However, existing cell aspiration devices have some deficiencies when used for immune cell detection of nerve infections.

[0003] On the one hand, during the cell aspiration process, it is difficult to precisely control the type and quantity of aspirated cells, and it is easy to mix in impurities such as overly large cells and adhered double cells, which affects the accuracy of subsequent detection results. These impurities may interfere with the normal analysis of immune cells, leading to misdiagnosis or missed diagnosis, and thus affecting the judgment and treatment of nerve infection diseases.

[0004] On the other hand, existing cell aspiration devices have defects in terms of operation convenience and stability. During long-term operation, due to the smooth surface or unreasonable design of the device, operators are prone to hand fatigue and hand slippage, which affects the accuracy and efficiency of the aspiration operation. Moreover, since the aspiration end of the cell aspirator is connected to the aspiration nozzle by interference fit, there is a risk of dropping during the cell aspiration process, and both installation and replacement require force to pull out. Therefore, it is of great practical significance to develop a cell aspiration device that can precisely filter immune cells for nerve infections, is convenient to operate, and is stable. Summary of the Invention

[0005] A technical solution for a cell aspiration device for immune cell detection for nerve infections is provided to address the defects proposed in the above background art.

[0006] It includes an aspirator, a cell filter is provided at the front end of the aspirator, an expansion and contraction structure is fixedly connected in the inner cavity of the cell filter, an aspiration nozzle is snap-connected to the front end of the cell filter, and a silica gel anti-slip member is wrapped around the outer circle of the rear section of the aspirator; )]]The aspirator includes an aspiration handle, an aspiration end fixed to the front end of the aspiration handle, and a control button provided at the front section of the outer surface of the aspiration handle, and the middle section on the outside of the aspiration handle is connected to the negative pressure suction pipe of the vacuum pump; The silicone anti-slip part includes an anti-slip jacket, a connector fixedly connected to the rear end face of the anti-slip jacket, and a canvas hanging strap fixedly connected to the rear end of the connector. A rubber restraint ring is sleeved on the outer surface of the canvas hanging strap; The cell filter part includes a sleeve screwed onto the front end of the suction head through threads, a front magnetic ring fixed to the rear section of the inner cavity of the sleeve, and a rear magnetic ring placed in the rear section of the inner cavity of the sleeve. A silicone ring is clamped between the rear magnetic ring and the front magnetic ring, and a filter membrane is fixed to the front side of the silicone ring; The expansion and contraction structure includes several support rods fixedly connected to the front section of the inner cavity side wall of the sleeve, a micro servo motor fixed to the converging ends of the support rods, and a lead screw connected to the output shaft of the micro servo motor through a coupling. A nut is movably threaded on the rear section of the outer circle of the lead screw, and a bearing is rotatably arranged at the front end of the outer circle of the lead screw. Among them, several groups of X-shaped hinge parts are hinged to the outer circles of the bearing and the nut, and the outer ends of the X-shaped hinge parts are respectively hinged with tile-shaped expansion pieces, and the outer surface of the tile-shaped expansion pieces contacts the inner cavity side wall of the suction nozzle.

[0007] In the above technical solution of a cell suction device for immunocyte detection for nerve infection, preferably: the front end of the suction head is provided with an external thread end nozzle for the rear end of the sleeve to be connected to the suction head through the external thread end nozzle, and the outer surface of the suction handle is fixedly connected to the inner cavity side wall of the anti-slip jacket through glue.

[0008] In the above technical solution of a cell suction device for immunocyte detection for nerve infection, preferably: the outer surface of the anti-slip jacket is provided with a concave surface that fits the human hand holding curve, and an opening for the control button and the negative pressure tube to pass through is provided on the outer side wall of the anti-slip jacket.

[0009] In the above technical solution of a cell suction device for immunocyte detection for nerve infection, preferably: the corners of the canvas hanging strap are all chamfered into arcs, and the inner surface of the canvas hanging strap contacts the human wrist in a winding manner. Multiple grooves are provided on the inner and outer side wall surfaces of the rubber restraint ring to increase the friction with the outer surface of the canvas hanging strap and realize the restraint of the opening and closing size of the rear section of the canvas hanging strap.

[0010] In the above technical solution of a cell suction device for immunocyte detection for nerve infection, preferably: the front section of the outer circle of the sleeve is inserted into the rear section area of the inner cavity of the suction nozzle, and a thread adapted to the external thread end nozzle at the front end of the suction head is provided at the rear end port of the sleeve.

[0011] In the above technical solution of a cell aspiration device for immune cell detection for nerve infection, preferably: the front magnetic ring and the rear magnetic ring are magnetically adsorbed to each other, and the side walls of the front magnetic ring and the rear magnetic ring close to each other are in close contact with the front and rear surfaces of the silica gel ring.

[0012] In the above technical solution of a cell aspiration device for immune cell detection for nerve infection, preferably: the periphery of the filter membrane has a plurality of holes for filtering oversized cells and bonding double cells.

[0013] In the above technical solution of a cell aspiration device for immune cell detection for nerve infection, preferably: the middle and rear sections of the lead screw are provided with threads adapted to the nut.

[0014] In the above technical solution of a cell aspiration device for immune cell detection for nerve infection, preferably: the X-shaped hinge pieces are arranged in a circular array with the central axis of the lead screw as the center point, and each X-shaped hinge piece is composed of two intersecting connecting rods. The front two ends of the X-shaped hinge piece are respectively hinged to the outer surface of the bearing and the front inner section of the tile-shaped expansion piece; wherein, the rear two ends of the X-shaped hinge piece are respectively hinged to the outer ring of the nut and slidably connected to the rear inner section of the tile-shaped expansion piece.

[0015] In the above technical solution of a cell aspiration device for immune cell detection for nerve infection, preferably: the rear inner sections of the tile-shaped expansion pieces are fixedly connected with chutes, and the outer rear ends of the X-shaped hinge pieces are connected with sliders adapted to the chutes.

[0016] As can be seen from the above technical solutions, the present invention provides a cell aspiration device for immune cell detection for nerve infection. Compared with the prior art, the present invention has the following beneficial effects: The cell aspirator provided by the present invention has a head set to an expandable and contractible structure, realizing rapid and effortless installation and replacement of the aspiration nozzle, while improving the connection firmness with the aspiration nozzle. Moreover, a jacket conforming to the hand-holding curve is provided on the periphery of the cell aspirator. The jacket has anti-slip patterns on its periphery, and the jacket can be clamped to the wrist to prevent the aspirator from detaching from the hand and increasing its stability. The inside of the aspiration head has a replaceable filter structure. The filter is connected by magnetic attraction, and the filter can be a mesh structure or a membrane structure, realizing the function of screening out oversized cells, bonding double cells, and even dead cells. Description of the Drawings

[0017] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce and explain the drawings required for describing the embodiments of the present invention or the prior art. Obviously, the drawings in the following description are only partial embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0018] Figure 1 Schematic diagram of the overall structure of the cell aspirator; Figure 2 Schematic diagram of the aspirator main body; Figure 3 Schematic diagram of the anti - detachment strap; Figure 4 Schematic diagram of the aspiration end and the aspiration nozzle; Figure 5 Schematic diagram of the cell filter element inside the aspiration end; Figure 6 Schematic diagram of the expansion - contraction structure inside the aspiration end.

[0019] Appendix Figure 1 - Appendix Figure 6 The corresponding relationships of the components in the following are as follows: 1. Aspirator; 11. Aspiration handle; 12. Aspiration end; 2. Silicone anti - slip part; 21. Anti - slip jacket; 22. Canvas strap; 23. Connector; 24. Rubber restraint ring; 3. Cell filter element; 31. Sleeve; 32. Filter membrane; 33. Silicone ring; 34. Rear magnetic ring; 35. Front magnetic ring; 4. Aspiration nozzle; 5. Expansion - contraction structure; 51. Support rod; 52. Micro servo motor; 53. Lead screw; 54. Nut; 55. Bearing; 56. Tile - shaped expansion piece; 57. X - shaped hinge; 58. Slide groove. Detailed implementation manners

[0020] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the drawings in the embodiments of the present invention. Obviously, the following described embodiments are only partial embodiments of the present invention, rather than all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention.

[0021] To more clearly explain and illustrate the technical solutions and implementation manners of the present invention, the following introduces the preferred specific embodiments for implementing the technical solutions of the present invention.

[0022] Embodiment 1: This embodiment is a basic implementation mode of a cell aspiration device for immune cell detection for nerve infection. The aspirator 1 includes an aspiration handle 11 and an aspiration tip 12. The front end of the aspiration handle 11 is fixedly connected to the aspiration tip 12, and a control button is provided on the front section of the outer surface. The middle section on the outside is connected to the negative pressure suction pipe of the vacuum pump. In the silica gel anti-slip member 2, the inner cavity side wall of the anti-slip jacket 21 is fixedly connected to the outer surface of the aspiration handle 11 by glue. The rear end face of the anti-slip jacket 21 is fixedly connected to the connecting head 23, and the rear end of the connecting head 23 is fixedly connected to the canvas hanging strap 22. A rubber restraint ring 24 is sleeved on the outer surface of the canvas hanging strap 22. The sleeve 31 of the cell filter member 3 is threadedly screwed to the aspiration tip 12 through the external thread nozzle at the front end of the aspiration tip 12. The front magnetic ring 35 is fixed in the middle and rear section of the inner cavity of the sleeve 31, and the rear magnetic ring 34 is placed in the rear section. The silica gel ring 33 is clamped between the rear magnetic ring 34 and the front magnetic ring 35. The filter membrane 32 is fixed on the front side of the silica gel ring 33. The filter membrane 32 has a plurality of holes for filtering oversized cells and bonding double cells throughout its body. In the expansion and contraction structure 5, several support rods 51 are fixedly connected to the front section of the inner cavity side wall of the sleeve 31. One end where the support rods 51 converge is fixedly connected to the micro servo motor 52. The lead screw 53 is connected to the output shaft of the micro servo motor 52 through a coupling. A movable nut 54 is threaded on the rear section of the outer circle of the lead screw 53. A bearing 55 is rotatably arranged at the front end of the outer circle. Several groups of X-shaped hinge members 57 are hinged between the bearing 55 and the outer circle of the nut 54. The outer ends of the X-shaped hinge members 57 are respectively hinged to the tile-shaped expansion pieces 56. The outer surface of the tile-shaped expansion pieces 56 contacts the inner cavity side wall of the aspiration nozzle 4. In actual use, the aspiration nozzle 4 is clamped to the front end of the cell filter member 3. The operator holds the aspiration handle 11 and controls the vacuum pump to perform negative pressure suction through the control button, so that the cells enter from the aspiration nozzle 4. When passing through the cell filter member 3, the filter membrane 32 filters out oversized cells and bonding double cells, and the cell aspiration is completed.

[0023] Embodiment 2: This embodiment focuses on describing the connection between the suction nozzle 4 and the cell filter element 3 and the adjustment process of the expansion and contraction structure 5. The front section of the outer circle of the sleeve 31 of the cell filter element 3 is inserted into the rear section area of the inner cavity of the suction nozzle 4. A thread adapted to the front outer threaded nozzle of the suction end 12 is provided at the rear end port of the sleeve 31 to achieve a stable connection between the sleeve 31 and the suction end 12. In the initial state of the expansion and contraction structure 5, the nut 54 is located on the rear section of the outer circle of the screw rod 53, close to the side of the micro servo motor 52. At this time, the X-shaped hinge 57 is in a contracted state, driving the tile-shaped expansion piece 56 to gather inward, making the inner cavity space of the suction nozzle 4 relatively small. When it is necessary to adjust the inner cavity space of the suction nozzle 4 to meet different cell suction requirements, the micro servo motor 52 is started through the control button. The micro servo motor 52 drives the screw rod 53 to rotate, and the nut 54 moves forward on the thread of the rear section of the outer circle of the screw rod 53, pushing the rear end of the X-shaped hinge 57 forward. Since the front two ends of the X-shaped hinge 57 are respectively hinged to the outer surface of the bearing 55 and the front section of the inner side of the tile-shaped expansion piece 56, and the rear two ends are respectively hinged to the outer circle of the nut 54 and slidably connected to the rear section of the inner side of the tile-shaped expansion piece 56, and a chute 58 is fixedly connected to the rear section of the inner side of the tile-shaped expansion piece 56, and a slider adapted to the chute 58 is connected to the outer rear end of the X-shaped hinge 57, the X-shaped hinge 57 gradually unfolds, driving the tile-shaped expansion piece 56 to expand outward, thereby increasing the inner cavity space of the suction nozzle 4 to meet the requirements of different cell suction.

[0024] Embodiment 3: This embodiment details the specific usage and function of the silicone anti-slip member 2. Concave surfaces conforming to the holding curve of the human hand are provided on the outer surface of the anti-slip jacket 21, which is convenient for the operator to hold the aspirator 1 and improves the comfort and stability of holding. Openings for the control button and the negative pressure pipe to pass through are provided on the outer side wall of the anti-slip jacket 21 to ensure the normal operation of the control button and the normal connection of the negative pressure pipe. Rounded chamfers are made at the corners of each strip of the canvas hanging strap 22 to avoid scratching the operator's wrist, and the inner surface of the canvas hanging strap 22 is wound and contacted with the human wrist. Multiple grooves are provided on the inner and outer side wall surfaces of the rubber restraint ring 24 to increase the friction with the outer surface of the canvas hanging strap 22. In actual use, the operator passes the wrist through the canvas hanging strap 22, adjusts the opening and closing size of the rear section of the canvas hanging strap 22 according to the thickness of the wrist, and then puts the rubber restraint ring 24 on the canvas hanging strap 22. By using the friction between the rubber restraint ring 24 and the canvas hanging strap 22, the opening and closing size of the rear section of the canvas hanging strap 22 is restricted, so that the aspirator 1 can be stably hung on the operator's wrist, which is convenient for carrying and using.

[0025] Example 4: This example illustrates the connection between the front and rear magnetic rings 35, 34, and the replacement process for the filter membrane 32 in the cell filter 3. The front and rear magnetic rings 35, 34 are magnetically attracted to each other, and the adjacent sidewalls of the front and rear magnetic rings 35, 34 are in close contact with the front and rear surfaces of the silicone ring 33. This connection ensures the stability of the silicone ring 33 and filter membrane 32 within the sleeve 31 while facilitating removal and replacement. To replace the filter membrane 32, the sleeve 31 is unscrewed from the aspiration tip 12. Due to the magnetic attraction between the front and rear magnetic rings 35, 34, the rear magnetic ring 34 can be easily removed from the sleeve 31. The silicone ring 33 and filter membrane 32 are then removed, and a new filter membrane 32 is replaced. The silicone ring 33, rear magnetic ring 34, and front magnetic ring 35 are then reinstalled. Finally, the sleeve 31 is screwed back onto the aspiration tip 12. This completes the replacement of the filter membrane 32, ensuring that the cell aspiration device can filter cells effectively.

[0026] According to the content of the preferred technical solution described above, the workflow of the technical solution is explained: the operator first passes the wrist through the canvas strap 22 in the silicone anti-slip part 2 according to actual usage needs and his own operating habits, adjusts the opening and closing size of the rear section of the canvas strap 22, and then puts the rubber restraint ring 24 on the canvas strap 22. The friction generated by the multiple grooves on the inner and outer wall surfaces of the rubber restraint ring 24 and the outer surface of the canvas strap 22 is used to constrain the opening and closing size of the rear section of the canvas strap 22, so that the suction device 1 is stably hung on the wrist, and at the same time, the palm of the hand holds the suction handle 11. At this time, the outer surface of the anti-slip jacket 21 fits the concave surface of the human hand grip curve to provide a comfortable grip experience, and the opening on the outer wall of the anti-slip jacket 21 does not affect the operation of the control button and the connection between the negative pressure tube and the outer middle section of the suction handle 11.

[0027] According to the situation of the cells to be sucked, if the inner cavity space of the suction nozzle 4 needs to be adjusted, the operator starts the micro servo motor 52 in the expansion and contraction structure 5 through the control button. The output shaft of the micro servo motor 52 drives the screw rod 53 to rotate. The thread adapted to the nut 54 is provided in the middle and rear section of the screw rod 53 so that the nut 54 moves on the thread of the rear section of the outer ring of the screw rod 53. Since the X-shaped hinges 57 are arranged in a ring array with the central axis of the screw rod 53 as the base point, and the X-shaped hinges 57 are composed of two cross-connected connecting rods, the two ends of the front side of the X-shaped hinges 57 are connected. They are respectively hinged to the outer surface of the bearing 55 and the inner front section of the tile-shaped expansion piece 56, and the two rear ends are respectively hinged to the outer ring of the nut 54 and slidingly connected to the inner rear section of the tile-shaped expansion piece 56, and the inner rear section of the tile-shaped expansion piece 56 is fixedly connected with a slide groove 58, and the rear outer end of the X-shaped hinge 57 is connected with a slider adapted to the slide groove 58. When the nut 54 moves, it pushes the rear end of the X-shaped hinge 57 to move, causing the X-shaped hinge 57 to gradually expand or contract, thereby driving the tile-shaped expansion piece 56 to expand outward or gather inward to dock with the suction nozzle 4.

[0028] Align the front end of the suction nozzle 4 with the nerve-infected immune cell sample to be aspirated. Start the vacuum pump by controlling the button. The negative pressure suction pipe of the vacuum pump is connected to the middle section on the outside of the suction handle 11, creating negative pressure inside the aspirator 1. Under the action of negative pressure, the cell sample enters the inner cavity of the cell filter 3 from the suction nozzle 4. After the cell sample enters the cell filter 3, it first passes through the filter membrane 32. The filter membrane 32 has multiple pores throughout its body for filtering oversized cells and adhering double cells. These pores block the oversized cells and adhering double cells in front of the filter membrane 32, while the qualified immune cells pass through the filter membrane 32 and continue to move backward; in the cell filter 3, the front magnetic ring 35 and the rear magnetic ring 34 are magnetically adsorbed to each other and are in close contact with the front and rear surfaces of the silica gel ring 33. The silica gel ring 33 plays a role in supporting and fixing the filter membrane 32, ensuring the stability of the filter membrane 32 when the cell sample passes through; the filtered immune cells continue to move backward, enter the suction handle 11 through the suction end 12, and are then collected into the corresponding collection device through the negative pressure suction pipe of the vacuum pump connected to the middle section on the outside of the suction handle 11.

[0029] When a cell aspiration operation is completed, turn off the vacuum pump. If it is necessary to replace the filter membrane 32, unscrew the sleeve 31 from the external threaded nozzle at the front end of the suction end 12. Due to the magnetic adsorption force between the front magnetic ring 35 and the rear magnetic ring 34, the rear magnetic ring 34 can be easily taken out of the sleeve 31, and then the silica gel ring 33 and the filter membrane 32 are taken out. Replace the new filter membrane 32 and reinstall the silica gel ring 33, the rear magnetic ring 34, and the front magnetic ring 35. Finally, screw the sleeve 31 back onto the suction end 12 for future use.

[0030] The present invention is not limited to the above-mentioned best implementation mode. Anyone should know that structural changes made under the inspiration of the present invention, as long as they have the same or similar technical solutions as the present invention, fall within the protection scope of the present invention. Finally, it should also be noted that the structures, proportions, sizes, etc. shown in the drawings of this specification are only used to cooperate with the content disclosed in the specification for those familiar with this technology to understand and read, and are not used to limit the limited conditions for the implementation of this application. Therefore, they do not have technical substance significance. Any modification of the structure, change of the proportional relationship, or adjustment of the size, without affecting the effects that this application can produce and the purposes that can be achieved, should still fall within the scope that the technical content disclosed in this application can cover.

Claims

1. An immunocyte detection cell aspiration device for nerve infections, comprising an aspirator (1), characterized in that: A cell filter element (3) is provided at the front end of the aspirator (1). An expansion and contraction structure (5) is fixedly connected in the inner cavity of the cell filter element (3). A suction nozzle (4) is snap-connected to the front end of the cell filter element (3). A silica gel anti-slip member (2) is wrapped around the outer circumference of the rear section of the aspirator (1). The aspirator (1) includes a suction handle (11), a suction head (12) fixed to the front end of the suction handle (11), and a control button provided at the front section of the outer surface of the suction handle (11). The middle section on the outer side of the suction handle (11) is connected to the negative pressure suction pipe of the vacuum pump. The silica gel anti-slip member (2) includes an anti-slip jacket (21), a connector (23) fixedly connected to the rear end face of the anti-slip jacket (21), and a canvas hanging strap (22) fixedly connected to the rear end of the connector (23). A rubber restraint ring (24) is sleeved on the outer surface of the canvas hanging strap (22). The cell filter element (3) includes a sleeve (31) screwed onto the front end of the suction head (12) by threads, a front magnetic ring (35) fixed to the rear section of the inner cavity of the sleeve (31), and a rear magnetic ring (34) placed in the rear section of the inner cavity of the sleeve (31). A silica gel ring (33) is clamped between the rear magnetic ring (34) and the front magnetic ring (35). A filter membrane (32) is fixed to the front side of the silica gel ring (33). The expansion and contraction structure (5) includes a plurality of support rods (51) fixedly connected to the front section of the inner cavity side wall of the sleeve (31), a micro servo motor (52) fixed to the converging ends of the support rods (51), and a lead screw (53) connected to the output shaft of the micro servo motor (52) through a coupling. A nut (54) is movably threaded on the rear section of the outer circumference of the lead screw (53). A bearing (55) is rotatably provided at the front end of the outer circumference of the lead screw (53). Among them, a plurality of groups of X-shaped hinge members (57) are hinged to the outer circumferences of the bearing (55) and the nut (54). The outer ends of the X-shaped hinge members (57) are respectively hinged to tile-shaped expansion pieces (56). The outer surface of the tile-shaped expansion pieces (56) contacts the inner cavity side wall of the suction nozzle (4).

2. The cell aspiration device for immune cell detection for nerve infection according to claim 1, wherein: A section of external thread end nozzle is provided at the front end of the suction head (12) for the rear end of the sleeve (31) to be connected to the suction head (12) through the external thread end nozzle. The outer surface of the suction handle (11) is fixedly connected to the inner cavity side wall of the anti-slip jacket (21) by glue.

3. The cell aspiration device for immunocyte detection used for nerve infection according to claim 1, wherein: A concave surface conforming to the human hand holding curve is provided on the outer surface of the anti-slip jacket (21). Openings for the control button and the negative pressure pipe to pass through are provided on the outer side wall of the anti-slip jacket (21).

4. A cell aspiration device for immune cell detection for nerve infection according to claim 1, characterized in that: The corners of each side of the canvas hanging strap (22) are chamfered into arcs. The inner surface of the canvas hanging strap (22) contacts the human wrist in a winding manner. A plurality of grooves are provided on the inner and outer side wall surfaces of the rubber restraint ring (24) to increase the friction with the outer surface of the canvas hanging strap (22) and realize the restraint of the opening and closing size of the rear section of the canvas hanging strap (22).

5. The cell aspiration device for immunocyte detection for nerve infection according to claim 1, wherein: The front section of the outer ring of the sleeve (31) is inserted into the rear section area of the inner cavity of the suction nozzle (4), and a thread adapted to the external threaded end nozzle at the front end of the suction head (12) is provided inside the rear end port of the sleeve (31).

6. The cell aspiration device for immune cell detection for nerve infection according to claim 1, wherein: The front magnetic ring (35) and the rear magnetic ring (34) are magnetically adsorbed to each other, and the side walls of the front magnetic ring (35) and the rear magnetic ring (34) close to each other are in close contact with the front and rear surfaces of the silica gel ring (33).

7. The cell aspiration device for immune cell detection for nerve infection according to claim 1, wherein: The periphery of the filter membrane (32) has a plurality of holes for filtering oversized cells and bonding double cells.

8. The cell aspiration device for immunocyte detection for nerve infection according to claim 1, wherein: A thread adapted to the lead screw nut (54) is provided in the middle and rear sections of the lead screw (53).

9. The cell aspiration device for immune cell detection used for nerve infection according to claim 1, wherein: The X-shaped hinge members (57) are arranged in a circular array with the central axis of the lead screw (53) as the base point, and each of the X-shaped hinge members (57) is composed of two intersecting connecting rods. The front two ends of the X-shaped hinge member (57) are respectively hinged to the outer surface of the bearing (55) and the front section inside of the tile-shaped expansion piece (56); among them, the rear two ends of the X-shaped hinge member (57) are respectively hinged to the outer ring of the lead screw nut (54) and slidably connected to the rear section inside of the tile-shaped expansion piece (56).

10. The cell aspiration device for immune cell detection used for nerve infection according to claim 1, wherein: Chutes (58) are fixedly connected to the rear section inside of the tile-shaped expansion pieces (56), and sliders adapted to the chutes (58) are connected to the outer rear ends of the X-shaped hinge members (57).

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