Device for monitoring salivary secretion volume of xerostomia

Abstract

The invention discloses a xerostomia salivary secretion volume monitoring device, and relates to the technical field of medical instruments, the xerostomia salivary secretion volume monitoring device comprises a buccal tablet, a measuring tube is embedded in a detection jack, a built-in cavity is internally provided with an electromagnetic flow sensor, and the electromagnetic flow sensor is provided with electrode plates oppositely arranged on the inner wall of the detection jack; the side walls of the edges of the two attaching flanges can make contact with the inner wall of the detection jack, a temporary closed annular cavity is formed between the side walls of the edges of the two attaching flanges and the inner wall of the detection jack, the outer surface wall of the buccal tablet is provided with a plurality of flowing sunken parts, the flowing sunken parts extend to the edge position of the end of the detection jack, and the dual-core processor receives and processes induction signals of the electromagnetic flow sensor. The buccal tablet designed by the invention can be conveniently contained in the oral cavity, can monitor the saliva secretion amount in the oral cavity of a patient in real time, can be disinfected, cleaned and reused, has digital monitoring results, provides objective indexes for evaluating xerostomia, and solves the problems that the severity of the xerostomia is difficult to quantify, and disease evaluation and treatment effect monitoring are not facilitated.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a monitoring device for the saliva secretion volume of xerostomia. Background Art

[0002] Xerostomia is the feeling of dry mouth or oral cavity, which is a symptom caused by the lack of saliva in the oral cavity. Its etiology is relatively complex and can be one of the manifestations of systemic diseases or caused by local factors. This disease can occur in a variety of diseases, such as Sjogren's syndrome, diabetes, pernicious anemia, oral diseases, Candida infections, radiotherapy and chemotherapy for head and neck cancers, and adverse reactions caused by drugs. Its main symptom is oral dryness. Patients often feel dry and sticky in the mouth, have difficulty swallowing, and need to drink water frequently. In addition, it may also be accompanied by symptoms such as bad breath, oral ulcers, and an increase in dental caries. Severe xerostomia patients may even have problems such as tongue pain and decreased taste. Long-term dry mouth may also lead to digestive system diseases such as esophagitis. The discomfort caused by severe xerostomia will affect the quality of life of patients and lead to psychological problems such as anxiety and depression.

[0003] Clinically, the saliva flow rate is generally measured to measure the saliva secretion volume in the patient's oral cavity within a certain period of time (such as 15 minutes). This is an important objective index for evaluating xerostomia, but it may be affected by the cooperation of patients and it is difficult to quantify the severity of xerostomia symptoms, which is not conducive to the evaluation of the condition and the monitoring of the treatment effect. Summary of the Invention

[0004] The purpose of the present invention is to provide a monitoring device for the saliva secretion volume of xerostomia to solve the problems raised in the above background art.

[0005] To achieve the above purpose, the present invention provides the following technical solution: A monitoring device for the saliva secretion volume of xerostomia, including a buccal tablet. The buccal tablet has an internal cavity, and the buccal tablet is also provided with a detection jack. A measuring tube is embedded in the detection jack. An electromagnetic flow sensor is arranged in the internal cavity. The electromagnetic flow sensor has electrode plates oppositely arranged on the inner wall of the detection jack.

[0006] Both axial ends of the measuring tube radially extend with fitting flanges. The side walls of the edges of the two fitting flanges can contact the inner wall of the detection jack and form a temporary closed annular cavity with the inner wall of the detection jack. The electrode plates are located in the temporary closed annular cavity.

[0007] The outer surface wall of the buccal tablet is provided with a plurality of flow depressions. The flow depressions extend to the edge position of the end of the detection jack. The buccal tablet is held in the oral cavity. The two openings at both ends of the detection jack and the plurality of flow depressions are used for saliva to flow into the measuring tube. When the saliva flows through the position opposite to the electrode plates, it cuts the magnetic induction line and generates an induced electromotive force.

[0008] It further includes a dual-core processor, which receives and processes the induction signals of the electromagnetic flow sensor.

[0009] In a further embodiment, the buccal tablet has two combined covers, and the edge side walls of the two combined covers are hermetically and fittingly joined to each other.

[0010] In a further embodiment, the flow recesses are formed on the surface walls of the two combined covers, and the flow recesses on the two combined covers are butted together.

[0011] In a further embodiment, the two combined covers bulge towards the mutually remote ends to form arc-shaped protruding ends. The surface wall of the arc-shaped protruding end is recessed and extended towards the center of the built-in cavity to have a hollow extended end. When the edge covers of the two combined covers are joined together, the ends of the two hollow extended ends are fittingly joined together to form a hollow sleeve, and the detection jack is arranged along the axial direction of the hollow sleeve.

[0012] In a further embodiment, the inner wall of the hollow extended end is provided with a rib in a ring structure, and the vertical height between the mutually remote side walls of the two ribs is equal to the vertical height between the opposite side walls of the two fitting flanges.

[0013] In a further embodiment, the end of the hollow extended end is provided with an installation notch, and the inner space of the installation notches of the two hollow extended ends is used for installing an electrode sheet.

[0014] In a further embodiment, the dual-core processor is built-in with an ADC module, and the ADC module converts the voltage / current signal output by the sensor into a digital value.

[0015] In a further embodiment, the dual-core processor is also built-in with a Bluetooth module, and the Bluetooth module is used for externally connecting to an intelligent terminal.

[0016] In a further embodiment, at least two connecting rods are fixed on the inner wall of the measuring tube, and an elastic arc-shaped rod is fixed at the end of the connecting rod, and an inner built-in clamp is sleeved between the outer walls of the two elastic arc-shaped rods.

[0017] In a further embodiment, when the two elastic arc-shaped rods are toggled from the arc state to the linear structure state, the inner built-in clamp is expanded and supported, and the sleeved space is increased for placing a chewing paraffin tablet or an acidic tablet. When the deformed elastic arc-shaped rods are released, the elastic arc-shaped rods are reset, and the inner built-in clamp is reset to tightly sleeve the chewing paraffin tablet or the acidic tablet.

[0018] Compared with the prior art, the beneficial effects of the present invention are:

[0019] The buccal tablets designed by the present invention are convenient to be held in the oral cavity, can monitor the salivary secretion volume in the patient's oral cavity in real time, can be disinfected, cleaned and reused, and the monitoring results are digitalized, providing an objective index for evaluating xerostomia, solving the problem that it is difficult to quantify the severity of xerostomia symptoms due to the influence of the patient's cooperation, which is not conducive to the evaluation of the condition and the monitoring of the treatment effect. Doctors can give professional dietary advice based on the monitoring results, bringing good monitoring effects to patients with xerostomia. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the main structure of the present invention;

[0021] Figure 2 It is a schematic diagram of the split structure of the main structure of the present invention;

[0022] Figure 3 It is a schematic diagram of the structure in which two combination covers of the present invention are assembled together;

[0023] Figure 4 It is a schematic diagram of the measuring tube structure of the present invention;

[0024] Figure 5 It is a half-sectional view of the structure in which two combination covers of the present invention are assembled together;

[0025] Figure 6 It is a half-sectional view of the structure of a single combination cover of the present invention;

[0026] Figure 7 It is a schematic diagram of the further improved structure of the main structure of the present invention;

[0027] Figure 8 It is a schematic diagram of the further improved structure of the measuring tube of the present invention;

[0028] Figure 9 It is a schematic diagram of the deformation of the built-in clamp of the present invention.

[0029] In the figure: 1. Combination cover; 11. Flow depression part; 12. Rib; 13. Hollow extension end; 2. Measuring tube; 21. Fitting flange; 22. Built-in clamp; 23. Elastic arc rod; 24. Link rod; 3. Dual-core processor; 4. Electromagnetic flow sensor; 41. Electrode plate. DETAILED DESCRIPTION OF THE INVENTION

[0030] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0031] Embodiment, this embodiment provides a device for monitoring saliva secretion of dry mouth, including a buccal piece, the buccal piece has a built-in cavity, and the buccal piece is also provided with a detection jack, specifically, as Figure 1 、 Figure 2 and Figure 5 As shown, the buccal tablet has two combination covers 1, and the edge side walls of the two combination covers 1 are in airtight contact with each other. The edge side walls of the two combination covers 1 can be brought into contact with each other by gluing or snapping. The built-in cavity reduces saliva adhesion and avoids residue affecting the accuracy.

[0032] A plurality of flow depressions 11 are provided on the outer wall of the buccal tablet, and the flow depressions 11 extend to the edge of the end of the detection socket. Figure 6 As shown, the flow depression 11 is provided on the surface wall of the two combination covers 1, that is, the flow depressions 11 on the surface walls of the upper and lower combination covers 1 are continuously arranged together. The advantage of this is that after the lozenge is put into the mouth, no matter which surface wall of the combination cover 1 is placed on any position of the parotid gland, submandibular gland, sublingual gland, or small salivary gland, the lozenge can be moved in the mouth by the patient's tongue, and the tongue can also push the secreted saliva to move. The flow depression 11 on the surface wall of the lozenge provides a convenient guide path for the flow of secreted saliva, avoiding the thickness of the combination cover 1, which hinders the saliva from flowing along the bottom wall of the combination cover 1 to the detection socket and causing less saliva in the monitoring socket. The saliva can flow along the flow depression 11 as shown in the figure. Figure 6 The device creeps in the directions indicated by the arrows and enters the detection socket.

[0033] Use Figure 6 The design shown can increase the amount of saliva entering the detection jack and improve detection accuracy.

[0034] like Figure 2 and Figure 3 As shown, the two combined covers 1 bulge toward one end away from each other to form an arc-shaped protruding end, and the surface wall of the arc-shaped protruding end is recessed toward the center of the built-in cavity to extend a hollow extension end 13. When the edge covers of the two combined covers 1 are closed together, the ends of the two hollow extension ends 13 fit together to form a hollow sleeve, and the detection socket is arranged along the axial direction of the hollow sleeve. A measuring tube 2 is embedded in the detection socket, and an electromagnetic flow sensor 4 is arranged in the built-in cavity. The electromagnetic flow sensor 4 has an electrode sheet 41 arranged relative to the inner wall of the detection socket. A mounting notch is provided at the end of the hollow extension end 13, and the space in the mounting notch of the two hollow extension ends 13 is used to install an electrode sheet 41. Fitting flanges 21 extend radially at both axial ends of the measuring tube 2, as shown in FIG. Figure 4 As shown, the edge side walls of the two fitting flanges 21 can contact the inner wall of the detection hole, and form a temporary closed annular cavity between the inner wall of the detection hole, and the electrode sheet 41 is located in the temporary closed annular cavity;

[0035] The buccal tablet is held in the mouth. The two ends of the detection jack are open, and multiple flow depressions 11 are provided for the flow of saliva. The saliva enters the measuring tube 2. When the saliva flows through the position opposite to the electrode plate 41, it cuts the magnetic induction line, generating an induced electromotive force. The electromagnetic induction measurement principle: The Faraday's law is applied to the saliva flow cutting the magnetic induction line to generate an induced electromotive force: E = BxVxD, where: E is the induced electromotive force, B is the magnetic induction intensity, V is the saliva flow rate, and D is the inner diameter of the measuring tube. It also includes a dual-core processor 3. A lithium battery is set in the built-in cavity and a 3.7V / 500mAh battery is used to supply power to the dual-core processor 3 and the electromagnetic flow sensor 4, supporting continuous monitoring for ≥12 hours. In addition, a wireless charging module (based on the Qi standard) is integrated in the built-in cavity, and the lithium battery realizes wireless charging to avoid frequent disassembly. The dual-core processor 3 receives and processes the induction signals of the electromagnetic flow sensor 4. Moreover, an ADC module is built in the dual-core processor 3. The ADC module converts the voltage / current signal output by the sensor into a digital value. The dual-core processor 3 adopts a preset flow rate integration algorithm to output the cumulative flow rate or the instantaneous flow rate value. At the same time, a Bluetooth module is also built in the dual-core processor 3, and the Bluetooth module is used to connect to an external intelligent terminal.

[0036] Specifically analyzed, the electromagnetic flow sensor 4 converts the saliva flow into an analog voltage signal (such as 0 - 5V, corresponding to a flow rate of 0 - 1mL / min). The dual-core processor 3 uses an ESP32 processor. The ESP32 processor samples the signal through the ADC. The output signal of the electromagnetic flow sensor 4 needs to be adapted to the ESP32 range through a voltage division circuit. The ADC (such as ADS1115) converts the voltage / current signal output by the sensor into a digital value, and the sampling rate ≥100Hz to ensure accuracy.

[0037] In addition, the dual-core processor 3 uses a moving average filter or a Kalman filter to remove noise (such as oral movement interference). At the same time, a temperature sensor (such as DS18B20) is integrated in the dual-core processor 3, and the influence of temperature change on the sensor sensitivity is corrected by the look-up table method. The ESP32 is connected directly to the mobile phone APP through the Bluetooth mode: using BLE (low-power Bluetooth) transmission. Abnormal alarm: Set a threshold (such as the secretion volume <0.1mL / min for 1 hour continuously), triggering an APP notification. For example: Call the wx.writeBLECharacteristicValue in the WeChat mini-program to send an instruction and listen for the onBLECharacteristicValueChange to receive data. Set different threshold reminders (for example, the resting saliva flow rate <0.2mL / min triggers a notification), and pop up a prompt on the mobile phone APP terminal and push the relevant education content to prompt the user's next action.

[0038] In summary, the buccal tablets designed by the present invention are convenient to be held in the oral cavity, can real-time monitor the saliva secretion volume in the patient's oral cavity, can be disinfected, cleaned and reused, and the monitoring results are digitalized, providing an objective index for evaluating xerostomia. It solves the problem that it is difficult to quantify the severity of xerostomia due to the influence of the patient's cooperation, which is not conducive to the evaluation of the condition and the monitoring of the treatment effect. Doctors can give professional dietary advice based on the monitoring results, bringing good monitoring effects to patients with xerostomia.

[0039] Measurement of resting saliva flow rate: 1. Normal value of saliva secretion volume in healthy adults: 0.3 - 0.5 ml / min (resting state). 2. When the saliva secretion volume in 15 minutes under the resting state is ≤ 0.1 ml / min and continuously lower than this value and accompanied by symptoms (such as dry oral mucosa, dysphagia), it can be diagnosed as xerostomia and requires doctor intervention. 3. When the saliva secretion volume in 15 minutes under the resting state is between 0.1 - 0.2 ml / min, it indicates a decrease in saliva secretion function. If accompanied by persistent symptoms, medical evaluation is also required.

[0040] Monitoring purposes: 1. Objectively evaluate the saliva secretion function: clarify the current severity of xerostomia by quantitatively detecting the saliva flow rate. 2. Assist in disease classification and etiological diagnosis: combine saliva component analysis (such as pH value, immunoglobulin, enzyme activity) to judge whether it is related to autoimmune diseases (such as Sjogren's syndrome). 3. Dynamically monitor the curative effect and prognosis: compare the changes in saliva secretion volume before and after treatment to verify the effectiveness of drugs or alternative therapies. Predict the risk of complications (such as dental caries, oral mucosal damage) and formulate preventive measures.

[0041] In this embodiment, further, there are rib strips 12 with an annular structure provided on the inner wall of the hollow extension end 13, and the vertical height between the side walls of the two rib strips 12 away from each other is equal to the vertical height between the opposite side walls of the two fitting flanges 21. The purpose of such a design is that when the measuring tube 2 is placed in the detection jack, one of the fitting flanges 21 needs to forcefully cross the two rib strips 12, and at the same time, the edge positions of the opposite side walls of the two fitting flanges 21 can respectively abut against the side walls of the two rib strips 12 away from each other, so as to stably place the measuring tube 2 inside the detection jack and it is not easy to shake and detach from the detection jack.

[0042] In addition to using the static secretion volume detection and monitoring method, the stimulation secretion method can also be used for monitoring, such as Figure 7 、 Figure 8 [[ID=We]]And Figure 9As shown, at least two connecting rods 24 are fixed to the inner wall of the measuring tube 2, and elastic curved rods 23 are fixed to the ends of the connecting rods 24. A built-in clamp 22 is sleeved between the outer walls of the two elastic curved rods 23. When the two elastic curved rods 23 are moved from the curved state to the straight-line structure state, the built-in clamp 22 is expanded, and the sleeve space is increased for inserting chewable paraffin slices or acidic tablets. When the deformed elastic curved rods 23 are released, the elastic curved rods 23 are reset, and the built-in clamp 22 is reset to tighten the chewable paraffin slices or acidic tablets. Under the stimulation of chewing paraffin slices or acidic tablets, the total secretion of the patient's oral taste buds within 15 minutes after stimulation is recorded. Normally, it is ≥0.5mL / min. If it is still lower than this value under stimulation, medical treatment should be sought promptly.

[0043] Finally, it's worth noting that the measuring tube 2 is made of medical-grade PEEK (polyetheretherketone) or alumina ceramic, which prevents metal ion precipitation and allows for long-term contact with saliva without reaction. The combination cap 1 is made of medical-grade stainless steel or ceramic, providing a cooling sensation when held in the mouth and can be disinfected, cleaned, and reused.

[0044] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A monitoring device for the saliva secretion volume of xerostomia, characterized in that, include: A buccal tablet, the buccal tablet having a built-in cavity, the buccal tablet further being provided with a detection jack, a measuring tube (2) being embedded in the detection jack, an electromagnetic flow sensor (4) being provided in the built-in cavity, the electromagnetic flow sensor (4) having an electrode sheet (41) arranged relative to the inner wall of the detection jack; Both axial ends of the measuring tube (2) are radially extended with fitting flanges (21), and the edge side walls of the two fitting flanges (21) are capable of contacting the inner wall of the detection socket, and a temporary closed annular cavity is formed between the two flanges and the inner wall of the detection socket, and the electrode sheet (41) is located in the temporary closed annular cavity; The outer wall of the buccal tablet is provided with a plurality of flow recesses (11), and the flow recesses (11) extend to the edge of the end of the detection socket. The buccal tablet is contained in the oral cavity, and the openings at both ends of the detection socket and the plurality of flow recesses (11) are used for saliva to flow into the measuring tube (2). When the saliva flows through the electrode sheet (41) facing the position, it cuts the magnetic flux lines and generates an induced electromotive force. It also includes a dual-core processor (3), which receives and processes the sensing signal of the electromagnetic flow sensor (4).

2. The xerostomia saliva secretion monitoring device according to claim 1, wherein The buccal tablet comprises two combined covers (1), and the edge side walls of the two combined covers (1) are tightly fitted to each other.

3. The xerostomia saliva secretion amount monitoring device according to claim 2, characterized in that, The flow recessed portion (11) is formed on the surface walls of the two combined covers (1), and the flow recessed portions (11) on the two combined covers (1) are butted against each other.

4. The xerostomia saliva secretion monitoring device according to claim 3, characterized in that, The two combined covers (1) bulge toward one end away from each other to form an arc-shaped protruding end, and the surface wall of the arc-shaped protruding end is recessed and extends toward the center of the built-in cavity to form a hollow extension end (13). When the edges of the two combined covers (1) are closed together, the ends of the two hollow extension ends (13) fit together to form a hollow sleeve, and the detection jack is arranged along the axial direction of the hollow sleeve.

5. The xerostomia saliva secretion amount monitoring device according to claim 4, characterized in that, The inner wall of the hollow extension end (13) is provided with a protruding strip (12) of an annular structure, and the vertical height between the side walls of the two protruding strips (12) that are away from each other is equal to the vertical height between the opposite side walls of the two fitting flanges (21).

6. The xerostomia saliva secretion amount monitoring device according to claim 4, characterized in that, The ends of the hollow extension ends (13) are provided with mounting notches, and the spaces within the mounting notches of the two hollow extension ends (13) are used for mounting an electrode sheet (41).

7. The xerostomia saliva secretion monitoring device according to claim 1, wherein The dual-core processor (3) is equipped with an ADC module, which converts the voltage / current signal output by the sensor into a digital value.

8. The xerostomia saliva secretion monitoring device according to claim 1, characterized in that The dual-core processor (3) also has a built-in Bluetooth module, and the Bluetooth module is used for connecting to an external intelligent terminal.

9. The xerostomia saliva secretion amount monitoring device according to any one of claims 1 or 8, characterized in that, At least two connecting rods (24) are fixed to the inner wall of the measuring tube (2), elastic arc rods (23) are fixed to the ends of the connecting rods (24), and a built-in clamp (22) is sleeved between the outer walls of the two elastic arc rods (23).

10. The xerostomia saliva secretion monitoring device according to claim 9, characterized in that When the two elastic arc-shaped rods (23) are moved from an arc-shaped state to a straight-line structure state, the built-in clamp (22) is expanded and the sleeve space is increased for inserting chewable paraffin slices or acid tablets. When the deformed elastic arc-shaped rods (23) are loosened, the elastic arc-shaped rods (23) are reset, and the built-in clamp (22) is reset to tightly sleeve the chewable paraffin slices or acid tablets.

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