Lower limb artery thrombus removing device

Abstract

The invention provides a lower limb artery thrombus removing device and a handle. A guide wire of a mechanism is arranged in a first catheter in a penetrating mode, the first catheter is arranged in a second catheter in a penetrating mode, the second catheter is arranged in a third catheter in a penetrating mode, and the third catheter is arranged in a fourth catheter in a penetrating mode; comprising a balloon which is fixedly arranged on the front portion of the outer wall of the third catheter, and an injection cavity is communicated with the interior of the balloon; comprising a first umbrella-shaped net and first connecting rods, the first connecting rods are evenly distributed around the axis of the first umbrella-shaped net, one ends of the first connecting rods are hinged to the inner side of the first umbrella-shaped net, and the other ends of the first connecting rods are hinged to the second guide pipe; a suction cavity is formed in the tube wall of the fourth catheter, and the front end of the suction cavity is communicated with the outside. The falling thrombus is captured through the umbrella-shaped net, re-embolism caused when the thrombus falls into the far end of the artery is avoided, and meanwhile the thrombus capturing device has the advantages of avoiding erythrocyte lysis caused by thrombus cutting, being high in trafficability, low in cost and the like.

Description

Technical Field

[0001] The present invention relates to the field of human necessities, in particular to the field of surgical instruments, and more particularly to a device for removing lower limb arterial thrombosis. Background Art

[0002] As one of the common acute and critical diseases in vascular surgery, acute lower limb arterial embolism is characterized by sudden onset, rapid progression, high amputation rate and mortality. At present, the clinical surgical treatment options include arterial thrombectomy, mechanical thrombectomy or aspiration thrombectomy (such as aspiration thrombectomy catheter) and local mechanical dissipation thrombectomy. However, each of the above options has its own advantages and disadvantages.

[0003] Arterial thrombectomy is relatively inexpensive, but it has a large trauma, requires high general conditions of the patient, has a large blindness, and has a very limited effect on the occlusion of medium and small arteries with a long lesion range or involving the distal limb. The risk of distal re-embolism caused by thrombus detachment is relatively high.

[0004] Mechanical thrombectomy or aspiration thrombectomy has achieved good results clinically. Mechanical thrombectomy devices are effective treatment means for acute lower limb arterial embolism, especially for large vessel embolism above the femoral-popliteal artery. However, mechanical thrombectomy devices have a very limited effect on the occlusion of medium and small arteries with a long lesion range or involving the distal limb, and multiple surgeries for thrombectomy are required, which causes great trauma to the patient; moreover, mechanical thrombectomy devices crush and loosen thrombus, increasing the risk of distal re-embolism caused by thrombus detachment. The cost of aspiration thrombectomy catheters is relatively high, and they are not routinely configured in the operating room.

[0005] Local mechanical dissipation thrombectomy often leads to hemodynamic changes and mechanical damage, resulting in lysis of red blood cells, leading to hemoglobinuria. Repeated use will lead to renal insufficiency and high cost.

[0006] Therefore, there is a clinical need for a more minimally invasive, safe, effective and economical device to treat acute lower limb arterial embolism, and it is hoped that the following defects can be overcome simultaneously: Re-embolism caused by thrombus falling into the distal artery after detachment.

[0007] Lysis of red blood cells caused by mechanical thrombectomy.

[0008] Poor passability requires a large incision, resulting in greater trauma to the patient.

[0009] The cost increase caused by precision and complex parts. Summary of the Invention

[0010] The object of the present invention is to provide a lower limb arterial thrombus removal device, and this lower limb arterial thrombus removal device aims to solve the technical problems in the prior art, such as re-embolism caused by thrombus falling into the distal artery after detachment, red blood cell lysis caused by mechanical thrombectomy, relatively poor passability requiring a larger incision, and cost increase due to precision and complex parts.

[0011] A lower limb arterial thrombus removal device includes a guide wire, a first catheter, a second catheter, a third catheter, and a fourth catheter; the guide wire is arranged inside the first catheter, the first catheter is arranged inside the second catheter, the second catheter is arranged inside the third catheter, and the third catheter is arranged inside the fourth catheter; the front end of the first catheter extends out from the front end of the second catheter, the front end of the second catheter extends out from the front end of the third catheter, and the front end of the third catheter extends out from the front end of the fourth catheter; it includes a balloon, the balloon is fixedly arranged at the front part of the outer wall of the third catheter, an injection cavity is formed inside the wall of the third catheter, and the injection cavity is communicated with the inside of the balloon; it includes a first umbrella-shaped net and more than two first connecting rods, the first umbrella-shaped net is coaxially and fixedly arranged at the front end of the outer wall of the first catheter, more than two of the first connecting rods are evenly distributed around the axis of the first umbrella-shaped net, one end of the first connecting rod is hinged to the inner side of the first umbrella-shaped net, and the other end of the first connecting rod is hinged to the front end of the second catheter; a suction cavity is formed inside the wall of the fourth catheter, and the front end of the suction cavity is communicated with the outside.

[0012] Furthermore, it includes a fifth catheter, a second umbrella-shaped net and more than two second connecting rods; the fifth catheter is arranged inside the fourth catheter, the third catheter is arranged inside the fifth catheter, and the front end of the fifth catheter is located between the front end of the fourth catheter and the front end of the third catheter; the second umbrella-shaped net is coaxially and fixedly arranged at the front end of the outer wall of the fifth catheter, more than two of the second connecting rods are evenly distributed around the axis of the second umbrella-shaped net, one end of the second connecting rod is hinged to the inner side of the second umbrella-shaped net, and the other end of the second connecting rod is hinged to the front end of the fourth catheter.

[0013] Furthermore, a contrast agent injection cavity is formed inside the guide wire, and the front end of the contrast agent injection cavity is communicated with the outside.

[0014] Furthermore, barbs are arranged on the outer wall of the balloon.

[0015] Even further, the number of the first connecting rods is four, and the number of the second connecting rods is four.

[0016] Further, a lower limb artery thrombus removal device further includes a first handle. The first handle includes a first handle body, on which a first slider and a second slider are provided. The first slider is fixedly connected to the rear end of the first catheter, and the second slider is fixedly connected to the rear end of the third catheter. The first handle body is further provided with a suction port, an injection port, and a guide wire port. The suction port communicates with the suction chamber. The injection port communicates with the injection chamber. The guide wire port communicates with the first catheter, and the guide wire passes through the guide wire port and penetrates into the first catheter.

[0017] Further, a lower limb artery thrombus removal device further includes a second handle. The second handle includes a second handle body, on which a first slider, a second slider, and a third slider are provided. The first slider is fixedly connected to the rear end of the first catheter, the second slider is fixedly connected to the rear end of the third catheter, and the third slider is fixedly connected to the rear end of the third catheter. The second handle body is further provided with a suction port, an injection port, and a guide wire port. The suction port communicates with the suction chamber. The injection port communicates with the injection chamber. The guide wire port communicates with the first catheter, and the guide wire passes through the guide wire port and penetrates into the first catheter.

[0018] Compared with the prior art, the effects of the present invention are positive and obvious: The first umbrella-shaped net of the present invention can be opened and closed by the relative sliding of the first catheter and the second catheter. After being opened in the blood vessel, it can capture the shed thrombus, avoiding re-embolism caused by the thrombus falling into the distal artery after detachment.

[0019] In the present invention, the thrombus is scraped off by the movement of the inflated balloon, and the shed thrombus is sucked out of the body by the suction chamber in the fourth catheter, without causing red blood cell lysis due to mechanical thrombus removal.

[0020] After the second umbrella-shaped net and the first umbrella-shaped net of the present invention are opened simultaneously, they form a thrombus suction space, thus preventing the shed thrombus from leaving this space area.

[0021] The first to fifth catheters of the present invention form a multi-layer sleeve structure, which are nested with each other, and the balloon, the first umbrella-shaped net, and the second umbrella-shaped net are controlled by the relative sliding between the catheters, reducing the space occupied by the control structure and improving the passing performance of the device in the blood vessel.

[0022] The multi-layer sleeve structure of the present invention does not require high-precision micro parts, thus reducing the manufacturing cost. Description of the Drawings

[0023] Figure 1 . Structural schematic diagram of the first embodiment in the present invention.

[0024] Figure 2Schematic diagram of the structure of the second embodiment in the present invention.

[0025] Figure 3 Longitudinal sectional structure schematic diagram of the second embodiment in the present invention.

[0026] Figure 4 Cross-sectional structure schematic diagram of the second embodiment in the present invention.

[0027] Figure 5 Schematic diagram of the operation step 1 of the second embodiment in the present invention.

[0028] Figure 6 Schematic diagram of the operation step 2 of the second embodiment in the present invention.

[0029] Figure 7 Schematic diagram of the operation step 3 of the second embodiment in the present invention.

[0030] Figure 8 Schematic diagram of the operation step 4 of the second embodiment in the present invention.

[0031] Figure 9 Schematic diagram of the operation step 5 of the second embodiment in the present invention.

[0032] Figure 10 Schematic diagram of the operation step 6 of the second embodiment in the present invention.

[0033] Figure 11 Schematic diagram of the structure of the third embodiment in the present invention.

[0034] Figure 12 Schematic diagram of the structure of the fourth embodiment in the present invention.

[0035] In the figure: 1, guide wire; 101, contrast agent injection cavity; 2, first catheter; 3, second catheter; 4, third catheter; 401, injection cavity; 5, fourth catheter; 501, aspiration cavity; 6, fifth catheter; 7, first umbrella-shaped net; 701, first connecting rod; 8, second umbrella-shaped net; 801, second connecting rod; 9, balloon; 901, reverse barbs; 10, blood vessel; 11, thrombus. Detailed implementation manners

[0036] The following embodiments will further illustrate the present invention, but do not limit the present invention thereby. Embodiment

[0037] As Figure 1 shown, this embodiment provides a lower limb arterial thrombus removal device and a handle used in conjunction therewith.

[0038] The lower limb artery thrombus removal device includes a guide wire 1, a first catheter 2, a second catheter 3, a third catheter 4, and a fourth catheter 5; the guide wire 1 is inserted into the first catheter 2, the first catheter 2 is inserted into the second catheter 3, the second catheter 3 is inserted into the third catheter 4, and the third catheter 4 is inserted into the fourth catheter 5, so that the first catheter 2, the second catheter 3, the third catheter 4, and the fourth catheter 5 form a multi-layer sleeve structure with a compact structure and good permeability in the blood vessel.

[0039] The front end of the first conduit 2 extends from the front end of the second conduit 3 , the front end of the second conduit 3 extends from the front end of the third conduit 4 , and the front end of the third conduit 4 extends from the front end of the fourth conduit 5 .

[0040] The device includes a balloon 9, which is fixedly arranged at the front part of the outer wall of the third catheter 4. An injection cavity 401 is opened in the wall of the third catheter 4, and the injection cavity 401 is connected to the interior of the balloon 9. Air can be injected or discharged into the balloon 9 through the injection cavity 401, thereby controlling the expansion or contraction of the balloon 9; a developer can also be injected to make it easier to observe the position of the balloon 9; the third catheter 4 slides between the second catheter 3 and the fourth catheter 5, driving the movement of the inflated balloon 9 in the blood vessel, scraping off the thrombus on the blood vessel wall, so that the red blood cell lysis and hemoglobinuria caused by mechanical thrombus cutting will not be caused.

[0041] The device comprises a first umbrella-shaped net 7 and two or more first connecting rods 701. The first umbrella-shaped net 7 is made of a plastic metal material and is coaxially fixed to the front end of the outer wall of the first conduit 2. The two or more first connecting rods 701 are evenly distributed around the axis of the first umbrella-shaped net 7. In this embodiment, to improve stability, four first connecting rods 701 are provided, evenly distributed in four directions around the axis of the first umbrella-shaped net 7. One end of the first connecting rod 701 is hinged to the inner side of the first umbrella-shaped net 7, and the other end of the first connecting rod 701 is hinged to the front end of the second conduit 3. This hinged structure is simple and reliable, and is less expensive than the complex structure of a mechanical bolt cutting device.

[0042] The first catheter 2 slides axially within the second catheter 3. When the front ends of the first catheter 2 and the second catheter 3 approach, the first connecting rod 701 expands the first umbrella-shaped net 7. This structure is similar to the connecting rod structure of a common umbrella. Once expanded within the blood vessel, the first umbrella-shaped net 7 captures dislodged thrombi, preventing them from flowing into the distal artery and causing re-embolism. When the first umbrella-shaped net 7 is retracted, any thrombi captured by the first umbrella-shaped net 7 are also retracted inside the first umbrella-shaped net 7 and are removed from the body along with the device when it is withdrawn.

[0043] A suction cavity 501 is provided in the wall of the fourth catheter 5 , the front end of the suction cavity 501 is connected to the outside world, and the rear end of the suction cavity 501 is connected to a suction device, which can be a syringe or a suction pump, so that the detached thrombus can be sucked out of the body through the suction cavity 501 .

[0044] The rear end of the device is connected to a first handle (not shown). The first handle includes a first handle body, on which a first slider and a second slider are provided. The first slider is fixedly connected to the rear end of the first catheter 2, and the second slider is fixedly connected to the rear end of the third catheter 3. By sliding the corresponding slider, the catheter connected to the slider can be axially slid. The sliding of the first catheter 2 can control the opening and closing of the first umbrella-shaped net 7; the sliding of the third catheter 4 can drive the movement of the balloon 9. The first handle is also provided with a suction port, an injection port, and a guidewire port. The suction port is connected to the suction chamber 501 for connecting to a suction device; the injection port is connected to the injection chamber 401 for injecting gas or developer into the balloon 9; the guidewire port is connected to the first catheter 2 for inserting the guidewire 1. Example

[0045] like Figures 2 to 4 As shown, this embodiment is a preferred solution of embodiment 1, and further includes a fifth conduit 6, a second umbrella-shaped net 8 and more than two second connecting rods 801; the fifth conduit 6 is inserted into the fourth conduit 5, and the third conduit 4 is inserted into the fifth conduit 6, and the front end of the fifth conduit 6 is located between the front end of the fourth conduit 5 and the front end of the third conduit 4, and the fifth conduit 6 can slide axially between the third conduit 4 and the fourth conduit 5.

[0046] The second umbrella-shaped net 8 is symmetrically identical to the first umbrella-shaped net 7 and is coaxially fixed to the front end of the outer wall of the fifth catheter 6. Two or more second connecting rods 801 are evenly distributed around the axis of the second umbrella-shaped net 8. One end of the second connecting rod 801 is hinged to the inner side of the second umbrella-shaped net 8, and the other end of the second connecting rod 801 is hinged to the front end of the fourth catheter 5. When the front end of the fifth catheter 6 approaches the front end of the fourth catheter 5, the second connecting rod 801 expands the second umbrella-shaped net 8. The simultaneous expansion of the second umbrella-shaped net 8 and the first umbrella-shaped net 7 creates a space for thrombus aspiration, thereby preventing dislodged thrombi from escaping this space. Dislodged thrombi are either aspirated by the aspiration chamber 501 or captured by the first umbrella-shaped net, further preventing dislodged thrombi from entering the blood vessel and causing re-embolism.

[0047] The rear end of the device is connected to a second handle (not shown in the figure). The second handle includes a second handle body, on which a first slider, a second slider and a third slider are arranged. The first slider is fixedly connected to the rear end of the first catheter 2, the second slider is fixedly connected to the rear end of the third catheter 3, and the third slider is fixedly connected to the rear end of the fifth catheter 3. By sliding the corresponding slider, the catheter connected to the slider can slide axially. The sliding of the first catheter 2 can control the opening and closing of the first umbrella-shaped net 7. The sliding of the third catheter 4 can drive the balloon 9 to move. The sliding of the fifth catheter 6 can control the opening and closing of the second umbrella-shaped net 8. At the same time, a suction port, an injection port and a guide wire port are also arranged on the second handle. The suction port is communicated with the suction cavity 501 for connecting a suction device. The injection port is communicated with the injection cavity 401 for injecting gas or a developer into the balloon 9. The guide wire port is communicated with the first catheter 2 for inserting the guide wire 1.

[0048] The usage steps of this embodiment are as follows.

[0049] Step 1: As Figure 5 shown, the device is introduced into the blood vessel 10, and the guide wire 1 is extended near the thrombus 11. The front end of the guide wire 1 penetrates the thrombus 11.

[0050] Step 2: As Figure 6 shown, the part of the device except the guide wire 1 passes through the thrombus 11 along the path where the guide wire 1 penetrates the thrombus 11, and the thrombus 11 is placed between the first umbrella-shaped net 7 and the second umbrella-shaped net 8, and the balloon 9 is placed in front of the thrombus 11.

[0051] Step 3: As Figure 7 shown, slide the first catheter 2 backward to open the first umbrella-shaped net 7, and slide the fifth catheter 6 backward to open the second umbrella-shaped net 8. The opening degrees of the first umbrella-shaped net 7 and the second umbrella-shaped net 8 are adjusted according to the diameter of the blood vessel 10, so that the outer edges of the first umbrella-shaped net 7 and the second umbrella-shaped net 8 are close to the inner wall of the blood vessel 10.

[0052] Step 4: As Figure 8 shown, inject air or a developer into the balloon 9 through the injection cavity 401 to make the balloon 9 expand, and the outer wall of the balloon 9 is close to the inner wall of the blood vessel 10.

[0053] Step 5: As Figure 9 shown, slide the third catheter 4 backward, and then move the balloon 9 backward. During the movement, the balloon 9 contacts the thrombus 11 and scrapes off the thrombus 11. A part of the shed thrombus 11 is brought to the front end of the fourth catheter 5 by the balloon 9 and then sucked away by the suction cavity 501, and the other part of the debris flows along the blood flow to the front end of the blood vessel 10 and is captured by the first umbrella-shaped net 7.

[0054] Step 6: As Figure 10As shown, the first catheter 2 is slid forward to collapse the first umbrella-shaped net 7, and the fifth catheter 6 is slid forward to collapse the second umbrella-shaped net 8. The balloon 9 is emptied and contracted through the injection cavity 401, and then the device is pulled out of the body along the blood vessel 10 to complete the cleaning of the thrombus 11. Example

[0055] like Figure 11 As shown, this embodiment is a preferred solution of embodiment 1. A contrast agent injection cavity 101 is provided in the guide wire 1 , and the front end of the contrast agent injection cavity 101 is communicated with the outside. Contrast agent can be injected into the blood vessel through the contrast agent injection cavity 101 , thereby facilitating the determination of the length and size of the thrombus. Example

[0056] like Figure 12 As shown, this embodiment is a preferred solution of embodiment one. The outer wall of the balloon 9 is densely covered with inverted spines 901. The tips of the inverted spines 901 face backward and the ends are rounded to avoid scratching the blood vessel wall. The inverted spines 901 can hook the thrombus, increase the friction between the balloon 9 and the thrombus, and make it easier for the balloon 9 to scrape off the thrombus.

[0057] Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein; and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A lower limb artery thrombus removal device, characterized in that: It includes a guide wire (1), a first catheter (2), a second catheter (3), a third catheter (4), and a fourth catheter (5); the guide wire (1) is threaded through the first catheter (2), the first catheter (2) is threaded through the second catheter (3), the second catheter (3) is threaded through the third catheter (4), and the third catheter (4) is threaded through the fourth catheter (5); The front end of the first catheter (2) extends out of the front end of the second catheter (3), the front end of the second catheter (3) extends out of the front end of the third catheter (4), and the front end of the third catheter (4) extends out of the front end of the fourth catheter (5); It includes a balloon (9), the balloon (9) is fixedly arranged at the front part of the outer wall of the third catheter (4), an injection cavity (401) is formed in the wall of the third catheter (4), and the injection cavity (401) is communicated with the inside of the balloon (9); It includes a first umbrella-shaped net (7) and more than two first connecting rods (701); the first umbrella-shaped net (7) is coaxially and fixedly arranged at the front end of the outer wall of the first catheter (2), and more than two first connecting rods (701) are evenly distributed around the axis of the first umbrella-shaped net (7), one end of the first connecting rod (701) is hinged to the inner side of the first umbrella-shaped net (7), and the other end of the first connecting rod (701) is hinged to the front end of the second catheter (3); An aspiration cavity (501) is formed in the wall of the fourth catheter (5), and the front end of the aspiration cavity (501) is communicated with the outside.

2. The lower limb artery thrombus removal device according to claim 1, characterized in that: It includes a fifth catheter (6), a second umbrella-shaped net (8) and more than two second connecting rods (801); The fifth catheter (6) is threaded through the fourth catheter (5), the third catheter (4) is threaded through the fifth catheter (6), and the front end of the fifth catheter (6) is located between the front end of the fourth catheter (5) and the front end of the third catheter (4); The second umbrella-shaped net (8) is coaxially and fixedly arranged at the front end of the outer wall of the fifth catheter (6), and more than two second connecting rods (801) are evenly distributed around the axis of the second umbrella-shaped net (8), one end of the second connecting rod (801) is hinged to the inner side of the second umbrella-shaped net (8), and the other end of the second connecting rod (801) is hinged to the front end of the fourth catheter (5).

3. The lower limb artery thrombus removal device according to claim 1, characterized in that: A contrast agent injection cavity (101) is formed in the guide wire (1), and the front end of the contrast agent injection cavity (101) is communicated with the outside.

4. The lower limb artery thrombus removal device according to claim 1, characterized in that: The outer wall of the balloon (9) is provided with barbs (901).

5. The lower limb artery thrombus removal device according to claim 2, characterized in that: The number of the first link rods (701) is four, and the number of the second link rods (801) is four.

6. The lower limb artery thrombus removal device according to claim 1, wherein: It further includes a first handle, and the first handle includes a first handle body. A first slider and a second slider are arranged on the first handle body. The first slider is fixedly connected to the rear end of the first catheter (2), and the second slider is fixedly connected to the rear end of the third catheter (4); A suction port, an injection port and a guide wire (1) port are further arranged on the first handle body; the suction port communicates with the suction cavity (501); the injection port communicates with the injection cavity (401); the guide wire (1) port communicates with the first catheter (2), and the guide wire (1) penetrates into the first catheter (2) through the guide wire (1) port.

7. The lower limb artery thrombus removal device according to claim 2, wherein: It further includes a second handle, and the second handle includes a second handle body. A first slider, a second slider and a third slider are arranged on the second handle body. The first slider is fixedly connected to the rear end of the first catheter (2), the second slider is fixedly connected to the rear end of the third catheter (4), and the third slider is fixedly connected to the rear end of the third catheter (4); A suction port, an injection port and a guide wire (1) port are further arranged on the second handle body; the suction port communicates with the suction cavity (501); the injection port communicates with the injection cavity (401); the guide wire (1) port communicates with the first catheter (2), and the guide wire (1) penetrates into the first catheter (2) through the guide wire (1) port.

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