Kit for detecting myasthenia gravis antibody

By designing a kit for storage frame and fixing components, the detection accuracy problem caused by asymmetric force during the mixing process of the reagent tube is solved, and the stable clamping and rotary mixing of the reagent tube is achieved, which improves the detection accuracy.

CN120397472APending Publication Date: 2025-08-01JIANGSU BIO-HYKON BIOLOGICAL TECH CO LTD
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Patent Information

Application Number
CN202510524330.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-24
Publication Date
2025-08-01

AI Technical Summary

Technical Problem

When the existing kit for myasthenia gravis antibody detection is inside the mixed reagent tube, the sample is subjected to asymmetrical force, resulting in a decrease in detection accuracy.

Method used

A reagent kit is designed, including a storage frame and fixing components, and through the meshing and clamping assembly of the gear rack and rack, the stable clamping and rotary mixing of the reagent tube is achieved, preventing precipitation or layering, and improving detection accuracy.

Benefits of technology

Through stable clamping and rotary mixing, the stability of the reagent tube during transportation is ensured, the detection time is shortened, the substance is prevented from precipitation or stratification, and the detection accuracy is improved.

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Abstract

The invention relates to the technical field of kits, in particular to a kit for detecting a myasthenia gravis antibody, and aims to solve the problem that subsequent detection accuracy is reduced due to disordered asymmetric acting force when samples in reagent tubes are mixed in the prior art. A pressing disc drives a short column to descend through downward pressing, a movable column is promoted to rotate through sliding of a round ball and a threaded groove, then a rack B is driven to move, two sets of clamping blocks are made to be close to each other, stable clamping is achieved in cooperation with a silica gel pad, and in the process that a storage frame filled with reagent tubes is pushed into an inner cavity, a gear is meshed with a rack A, a shell is driven to rotate, and the reagent tubes are made to rotate in a specific mode; the sample is uniformly mixed and is rotated again when being taken out, so that substances in the reagent tube are prevented from generating a precipitation or layering phenomenon, and the subsequent detection accuracy is finally improved.
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Description

Technical Field

[0001] The present invention relates to the technical field of reagent kits, and particularly relates to a reagent kit for detecting myasthenia gravis antibodies. Background Art

[0002] A reagent kit is a device specifically used for storing, protecting, and managing reagent tubes. It is usually made of suitable materials and has internal partitions, brackets, and other structures. The reagent kit provides physical protection to prevent the reagent tubes from being damaged by external forces such as collision and extrusion during transportation and storage.

[0003] In the Chinese patent with the publication number CN220663275U, a reagent kit for detecting myasthenia gravis antibodies is disclosed. Before taking the reagent, the switch is turned on to make the chemical reagent in the reagent tube shake left and right, so that the reagent can be shaken evenly, reducing the need for the operator to shake the reagent again. The taking is simple and convenient, effectively improving the use efficiency.

[0004] In the above patent during operation, although the reagent tube can be shaken, since the shaking makes the upper and lower ends of the reagent tube move in two different directions respectively, the sample in the reagent tube is subjected to disordered and asymmetric acting forces during shaking. This acting force will cause the centripetal force and centrifugal force received by each component of the sample to be unbalanced, forming a complex and disordered flow state in the tube, interfering with the sample uniformity, and resulting in the problem of reduced subsequent detection accuracy.

[0005] Therefore, we propose a reagent kit for detecting myasthenia gravis antibodies. Summary of the Invention

[0006] The technical problem to be solved by the present invention is to overcome the defects existing in the prior art. The present invention proposes a reagent kit for detecting myasthenia gravis antibodies, which solves the problem of reduced subsequent detection accuracy due to disordered and asymmetric acting forces when mixing the sample inside the reagent tube in the background art.

[0007] To solve the above technical problem, the technical solution adopted by the present invention is: a reagent kit for detecting myasthenia gravis antibodies, including a reagent kit. A storage frame is movably arranged inside the reagent kit, a reagent tube is arranged inside the storage frame, an inner cavity is opened inside the reagent kit, a bottom groove is opened at the bottom of the inner cavity, one end of the bottom groove penetrates through one side of the reagent kit, and a rack A is fixedly installed on the inner wall of the bottom groove; Inside the storage box, a fixing component for fixing reagent tubes is movably arranged. The fixing component includes a housing movably arranged inside the storage box. A bottom post is fixedly installed on the lower surface of the housing. The bottom post is movably connected to the bottom of the storage box. One end of the bottom post penetrates through the bottom of the storage box. A gear is sleeved on the outer surface of the bottom post. The gear and the rack A are on the same horizontal line and are meshed with each other. Inside the housing, a clamping component for clamping the reagent tube is movably arranged. Inside the housing, a linkage component for driving the clamping component to clamp the reagent tube is arranged. A buckle component for fixing the position of the clamping component is fixedly installed on the surface of the linkage component.

[0008] Further, the linkage component includes a movable post movably arranged inside the housing. A short post is movably arranged inside the movable post. A spherical ball is fixedly installed on the outer surface of the short post. A threaded groove is formed in the inner wall of the movable post. The spherical ball is slidably connected to the threaded groove. A pressing plate is fixedly installed on the upper surface of the short post. The upper surface of the pressing plate is attached to the lower surface of the reagent tube. A spring rod and a buckle component are fixedly installed on the lower surface of the pressing plate. A tooth hole is formed in the lower surface of the movable post.

[0009] Further, two sets of clamping components are provided. The two sets of clamping components include clamping blocks movably arranged inside the housing. A silica gel pad is fixedly installed on one side of the clamping block. A vertical rod is fixedly installed on the lower surface of the clamping block. A rack B is fixedly installed on one side of the vertical rod. Both sets of rack B are meshed with the tooth hole. The tooth hole is located between the two sets of rack B.

[0010] Further, a hole groove is formed in the surface of the housing. The hole groove is located between the two sets of clamping blocks. A block groove is formed inside the housing. The clamping block is slidably arranged in the block groove. A vertical groove is formed at the bottom of the block groove. The vertical rod is slidably connected to the vertical groove. A disc groove is formed inside the housing. The pressing plate is slidably connected to the disc groove. Two sets of storage grooves are formed at the bottom of the disc groove. The storage grooves are adapted to the buckle component. A column groove is also formed at the bottom of the disc groove. The column groove is located between the two sets of storage grooves. A horizontal groove is formed in the inner wall of the vertical groove. The horizontal groove is communicated with the column groove. The rack B is movably connected to the column groove. The rack B is meshed with the tooth hole through the column groove. The lower surface of the spring rod is fixedly installed with the bottom of the column groove. The lower surface of the movable post is movably connected to the bottom of the column groove.

[0011] Further, the buckle component includes a fixing plate fixedly installed on the lower surface of the pressing plate. A first chute, a second chute, a third chute and a fourth chute are formed on the surface of the fixing plate. The first chute is lower than the fourth chute. The second chute is lower than the first chute. The third chute is lower than the second chute. One end of the fourth chute is provided with a slope. One end of the slope is in contact with one end of the third chute. A Z-shaped rod is arranged inside the first chute. The other end of the Z-shaped rod is movably connected to the inner wall of the disc groove.

[0012] Furthermore, one end of the Z-shaped rod is provided with a groove, and a reset spring is fixedly installed on the inner wall of the groove. A T-shaped rod is arranged inside the groove. The reset spring is sleeved on the outer surface of the T-shaped rod. One end of the reset spring is fixedly connected to the inner wall of the groove, and the other end of the reset spring is fixedly connected to one side of the T-shaped rod. A rolling ball is movably arranged at one end of the T-shaped rod.

[0013] Furthermore, a handle is fixedly installed on one side of the storage box. Baffles, T-shaped blocks and cross plates are fixedly installed on both sides of the storage box. The baffle is arranged on the side close to the handle, and the T-shaped block and the cross plate are arranged on the side far from the handle. The T-shaped block is located below the cross plate. A ladder plate is fixedly installed at one end of the cross plate. A rectangular plate is fixedly installed on the upper surface of the storage box. There are four groups of rectangular plates, and two groups of rectangular plates are respectively arranged on one side and the other side of the storage box. A bottom plate is arranged on the lower surface of the storage box close to the handle. The bottom plate is adapted to the bottom groove. The cross plate and the baffle are on the same horizontal line.

[0014] Furthermore, the reagent kit is provided with a rectangular opening and an inner groove. The inner cavity is adapted to the rectangular plate, and the inner groove is adapted to the baffle. The ladder plate is movably connected to the inner groove through the cross plate. A rectangular groove is opened inside the reagent kit. A rod groove is opened at the bottom of the inner groove. The rectangular groove is communicated with the inner groove through the rod groove. A disinfection component for disinfection and sterilization is fixedly installed on the surface of the reagent kit. A T-shaped groove is opened on the inner wall of the inner cavity. The T-shaped groove is slidably connected to the T-shaped block.

[0015] Furthermore, the disinfection component includes a temporary storage box on the surface of the reagent kit. A liquid box is fixedly installed inside the rectangular groove. A liquid inlet pipe is fixedly installed between the temporary storage box and the liquid box. A spray pipe is fixedly installed on one side of the liquid box. One end of the spray pipe is inside the inner cavity. The spray pipe is located above the storage box. An extrusion plate is movably arranged inside the liquid box. A fixing rod is fixedly installed on the lower surface of the extrusion plate. The fixing rod is adapted to the rod groove.

[0016] [[ID=,12]]Furthermore, an inclined groove is fixedly installed on the lower surface of the fixing rod. There are two groups of inclined grooves, and both groups of inclined grooves are adapted to both sides of the ladder plate.

[0017] Compared with the prior art, the beneficial effects of the present invention are: A kit for detecting myasthenia gravis antibodies proposed by the present invention, when placed in a reagent tube, the storage frame is pulled out from the inside of the inner cavity. Then, after the reagent tube is placed inside the hole groove, it is pressed down with the reagent tube, causing the pressure plate to drive the short column to descend, thereby rotating the toothed hole, making the two clamping blocks approach each other, and thus fixing and clamping the reagent tube. When the storage frame is filled with reagent tubes, the storage frame is pushed back into the inner cavity again. At this time, the bottom column on the lower surface of the outer shell will rotate the outer shell because the gear meshes with the bottom groove, thereby initially mixing the samples inside the reagent tubes. When the storage frame completely enters the inner cavity, the reagent tube will stop rotating until the storage frame is pulled out again, and the reagent tube will rotate again, preventing precipitation or stratification of the substances inside the reagent tube, and finally improving the accuracy of subsequent detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The disclosure of the present invention will be described with reference to the accompanying drawings. It should be understood that the drawings are only for illustrative purposes and are not intended to limit the scope of protection of the present invention. In the drawings, the same reference numerals are used to refer to the same components. Among them: Figure 1 Schematically shows the overall schematic diagram proposed according to an embodiment of the present invention Figure 1 ; Figure 2 Schematically shows the overall schematic diagram proposed according to an embodiment of the present invention Figure 2 ; Figure 3 Schematically shows the internal schematic diagram of the kit proposed according to an embodiment of the present invention Figure 1 ; Figure 4 Schematically shows the internal schematic diagram of the kit proposed according to an embodiment of the present invention Figure 2 ; Figure 5 Schematically shows the schematic diagram of the storage frame proposed according to an embodiment of the present invention; Figure 6 Schematically shows the schematic diagram of the fixing component proposed according to an embodiment of the present invention; Figure 7 Schematically shows the internal schematic diagram of the fixing component proposed according to an embodiment of the present invention; Figure 8 Schematically shows the disassembled schematic diagram of the fixing component proposed according to an embodiment of the present invention; Figure 9 Schematically shows the internal and short column schematic diagram of the movable column proposed according to an embodiment of the present invention; Figure 10 Schematically shows the schematic diagram of the fixing plate proposed according to an embodiment of the present invention; Figure 11 Schematically shows an internal schematic diagram of a Z-shaped rod proposed according to an embodiment of the present invention; Figure 12 Schematically shows a schematic diagram of a disinfection component proposed according to an embodiment of the present invention.

[0019] Reference numerals in the figure: 1, kit; 11, inner cavity; 12, rectangular opening; 13, inner groove; 14, bottom groove; 15, rack A; 16, rectangular groove; 17, T-shaped groove; 2, storage frame; 21, baffle; 22, handle; 23, bottom plate; 24, T-shaped block; 25, cross plate; 251, ladder plate; 26, fixing component; 261, outer shell; 2611, hole groove; 2612, block groove; 2613, vertical groove; 2614, disc groove; 2615, storage groove; 2616, horizontal groove; 2617, column groove; 262, bottom column; 263, gear; 264, clamping component; 2641, clamping block; 2642, silica gel pad; 2643, vertical rod; 2644, rack B; 265, linkage component; 2651, movable column; 2652, short column; 2653, spherical ball; 2654, threaded groove; 2655, pressing disc; 2656, tooth hole; 2657, spring rod; 27, rectangular plate; 3, disinfection component; 31, temporary storage box; 32, liquid box; 33, liquid inlet pipe; 34, spray pipe; 35, extrusion plate; 36, fixing rod; 37, inclined groove; 4, reagent tube; 5, buckle component; 51, fixing plate; 52, first chute; 53, second chute; 54, third chute; 55, fourth chute; 56, slope; 57, Z-shaped rod; 571, groove; 572, return spring; 573, T-shaped rod; 574, rolling ball. Detailed implementation manners

[0020] It is easy to understand that according to the technical solution of the present invention, without changing the essential spirit of the present invention, those of ordinary skill in the art can propose various interchangeable structural ways and implementation ways. Therefore, the following detailed implementation manners and the accompanying drawings are only exemplary descriptions of the technical solution of the present invention, and should not be regarded as all of the present invention or as a limitation or restriction on the technical solution of the present invention. Embodiment

[0021] To solve the technical problem of how to improve the subsequent detection effect of the reagent tube, as Figures 1-9 shown, the following preferred technical solution is provided: A kit for detecting myasthenia gravis antibodies, including a kit 1, a storage frame 2 is movably arranged inside the kit 1, a reagent tube 4 is arranged inside the storage frame 2, an inner cavity 11 is opened inside the kit 1, a bottom groove 14 is opened at the bottom of the inner cavity 11, one end of the bottom groove 14 penetrates through one side of the kit 1, and a rack A 15 is fixedly installed on the inner wall of the bottom groove 14; Inside the storage frame 2, a fixing component 26 for fixing the reagent tube 4 is movably arranged. The fixing component 26 includes a housing 261 movably arranged inside the storage frame 2. A bottom column 262 is fixedly installed on the lower surface of the housing 261. The bottom column 262 is movably connected to the bottom of the storage frame 2. One end of the bottom column 262 penetrates through the bottom of the storage frame 2. A gear 263 is sleeved on the outer surface of the bottom column 262. The gear 263 is on the same horizontal line as the rack A15, and the gear 263 meshes with the rack A15. Inside the housing 261, a clamping component 264 for clamping the reagent tube 4 is movably arranged. Inside the housing 261, a linkage component 265 for driving the clamping component 264 to clamp the reagent tube 4 is arranged. A buckle component 5 for fixing the position of the clamping component 264 is fixedly installed on the surface of the linkage component 265. Through the linkage component 265, when the reagent tube 4 is placed inside the housing 261 and the lower surface of the reagent tube 4 touches the linkage component 265, the linkage component 265 is pressed down, enabling the linkage component 265 to drive the clamping component 264 to move, so that the clamping component 264 clamps the reagent tube 4. When the linkage component 265 continues to descend, the buckle component 5 also starts to work. When the linkage component 265 descends to a certain height, the buckle component 5 will fix the linkage component 265, thereby indirectly fixing the linkage component 265. At this point, the reagent tube 4 is fixed, ensuring the stability of the reagent tube 4 during transportation. Subsequently, when the storage frame 2 is filled with reagent tubes 4, the storage frame 2 can be inserted into the inner cavity 11. When the storage frame 2 starts to move into the inner cavity 11, the gear 263 meshes with the bottom groove 14, driving the housing 261 to rotate, and further enabling the liquid inside the reagent tube 4 to react more quickly, thus shortening the subsequent detection time. When the storage frame 2 is completely inserted into the inner cavity 11, the housing 261 stops rotating, allowing the antibody and antigen inside the reagent tube 4 to reach equilibrium, ensuring the accuracy of the detection result. Finally, when the reagent tube 4 is taken out, the storage frame 2 is pulled out of the inner cavity 11 again. At this time, the housing 261 will drive the reagent tube 4 to rotate again, preventing the substances inside the reagent tube 4 from precipitating or stratifying, and ultimately improving the accuracy of subsequent detection.

[0022] The linkage component 265 includes a movable post 2651 movably arranged inside the housing 261. A short post 2652 is movably arranged inside the movable post 2651. A spherical ball 2653 is fixedly installed on the outer surface of the short post 2652. A threaded groove 2654 is formed in the inner wall of the movable post 2651. The spherical ball 2653 is slidably connected with the threaded groove 2654. A pressure plate 2655 is fixedly installed on the upper surface of the short post 2652. The upper surface of the pressure plate 2655 is in contact with the lower surface of the reagent tube 4. A spring rod 2657 and a buckle assembly 5 are fixedly installed on the lower surface of the pressure plate 2655. A tooth hole 2656 is formed in the lower surface of the movable post 2651. After the reagent tube 4 is placed on the surface of the pressure plate 2655, press the pressure plate 2655 to make the pressure plate 2655 drive the short post 2652 to descend. Since the movable post 2651 is movably arranged inside the housing 261, and the pressure plate 2655 is fixedly connected with the short post 2652, and the pressure plate 2655 is also fixedly connected with the spring rod 2657, when the pressure plate 2655 drives the short post 2652 to descend, the spherical ball 2653 will move along the threaded groove 2654. However, because the short post 2652 descends fixedly, the movable post 2651 will rotate. At this time, the rotating movable post 2651 will drive the two clamping components 264 to approach each other, thereby clamping the reagent tube 4. Because the existing reagent tubes 4 are directly placed inside a fixed rack during storage, common reagent kits mostly adopt simple placement. And when storing the reagent tubes 4, there will be a gap between the reagent tubes 4 and the holes. This gap is prone to shaking, displacement or even falling during subsequent movement. In addition, in the face of reagent tubes 4 of different specifications, the adjustment and adaptation ability is poor. Basically, one reagent kit is adapted to reagent tubes 4 of a specific specification, so it is difficult to adapt to reagent tubes 4 of different specifications.

[0023] There are two sets of clamping components 264. The two sets of clamping components 264 include clamping blocks 2641 movably arranged inside the housing 261. A silica gel pad 2642 is fixedly installed on one side of the clamping block 2641. A vertical rod 2643 is fixedly installed on the lower surface of the clamping block 2641. A rack B2644 is fixedly installed on one side of the vertical rod 2643. Both sets of racks B2644 are engaged with the tooth holes 2656. The tooth holes 2656 are located between the two sets of racks B2644. When the tooth holes 2656 rotate as the pressure plate 2655 descends, the racks B2644 can be driven to move through the engagement of the racks B2644 with the tooth holes 2656, thereby driving the two clamping blocks 2641 to approach each other to fixedly clamp the reagent tube 4. The silica gel pad 2642 on one side of the clamping block 2641 increases the friction between the reagent tube 4 and the silica gel pad 2642 due to its own characteristics, preventing the clamped reagent tube 4 from moving up and down. In the existing reagent kits, when storing the reagent tube 4, the reagent tube 4 is directly placed into the holes. The storage plates for storing the reagent tube 4 inside the existing reagent kits are generally made of plastic. Since the plastic material is relatively smooth, the friction between it and the reagent tube 4 is extremely small and the sliding property is very large. When the reagent kit is slightly vibrated during daily movement and transportation, the reagent tube 4 will slide and shift randomly in the holes of the storage plate.

[0024] Hole grooves 2611 are formed on the surface of the housing 261. The hole grooves 2611 are located between the two clamping blocks 2641. Block grooves 2612 are formed inside the housing 261. The clamping blocks 2641 are slidably arranged in the block grooves 2612. Vertical grooves 2613 are formed at the bottom of the block grooves 2612. The vertical rods 2643 are slidably connected to the vertical grooves 2613. Disc grooves 2614 are formed inside the housing 261. The pressure plates 2655 are slidably connected to the disc grooves 2614. Storage grooves 2615 are formed at the bottom of the disc grooves 2614. There are two sets of storage grooves 2615, which are adapted to the buckle components 5. A column groove 2617 is also formed at the bottom of the disc grooves 2614. The column groove 2617 is located between the two sets of storage grooves 2615. Horizontal grooves 2616 are formed on the inner wall of the vertical grooves 2613. The horizontal grooves 2616 are communicated with the column groove 2617. The rack B2644 is movably connected to the column groove 2617. The rack B2644 is engaged with the tooth hole 2656 through the column groove 2617. The lower surface of the spring rod 2657 is fixedly installed at the bottom of the column groove 2617. The lower surface of the movable column 2651 is movably connected to the bottom of the column groove 2617. Through the block grooves 2612, the clamping blocks 2641 can move smoothly. Then, through the column groove 2617, the teeth of the rack B2644 can be brought into contact with the tooth holes 2656. Finally, through the vertical grooves 2613 and the column groove 2617, the vertical rods 2643 and the rack B2644 can move inside the housing 261.

[0025] The snap component 5 includes a fixing plate 51 fixedly installed on the lower surface of the pressure plate 2655. The surface of the fixing plate 51 is provided with a first chute 52, a second chute 53, a third chute 54, and a fourth chute 55. The first chute 52 is lower than the fourth chute 55, the second chute 53 is lower than the first chute 52, the third chute 54 is lower than the second chute 53, and one end of the fourth chute 55 is provided with a slope 56. One end of the slope 56 is in contact with one end of the third chute 54. A Z-shaped rod 57 is arranged inside the first chute 52, and the other end of the Z-shaped rod 57 is movably connected to the inner wall of the disk groove 2614. When the pressure plate 2655 starts to descend, one end of the Z-shaped rod 57 will move along the first chute 52. When the pressure plate 2655 moves to the lowest end, one end of the Z-shaped rod 57 will move to one end of the second chute 53, and at this time, the clamping force of the clamping component 264 will reach the maximum value. Since there is the protection of the clamping block 2641, it will not cause damage to the reagent tube 4. Then, release the force pressing the pressure plate 2655, and the spring rod 2657 will reset, causing the Z-shaped rod 57 to move to one end of the third chute 54, so that one end of the Z-shaped rod 57 is stuck at one end of the third chute 54. Thus, the clamping component 264 completely clamps the reagent tube 4. When the reagent tube 4 is needed, just press the pressure plate 2655 again to make the Z-shaped rod 57 return to one end of the first chute 52 along the third chute 54, the slope 56, and the fourth chute 55. Some existing fixing structures for reagent tubes 4 usually need to manually tighten and fasten the reagent tube 4, etc. The operation is cumbersome and time-consuming, making the efficiency extremely low when processing a batch of reagent tubes 4.

[0026] A groove 571 is formed at one end of the Z-shaped rod 57. A return spring 572 is fixedly installed on the inner wall of the groove 571. A T-shaped rod 573 is arranged inside the groove 571. The return spring 572 is sleeved on the outer surface of the T-shaped rod 573. One end of the return spring 572 is fixedly connected to the inner wall of the groove 571, and the other end of the return spring 572 is fixedly connected to one side of the T-shaped rod 573. A rolling ball 574 is movably arranged at one end of the T-shaped rod 573. The return spring 572 can make the T-shaped rod 573 extend out of the groove 571, so as to adapt to the first chute 52, the second chute 53, the third chute 54, and the fourth chute 55. When the end of the Z-shaped rod 57 with the T-shaped rod 573 passes through the second chute 53 and the third chute 54, the T-shaped rod 573 will be gradually extended by the return spring 572, so that the outer surface of the rolling ball 574 can contact the bottom surfaces of the second chute 53 and the third chute 54. When the T-shaped rod 573 moves to the slope 56, the T-shaped rod 573 will gradually move into the groove 571 until the T-shaped rod 573 moves back to the first chute 52.

[0027] Specifically, when it is necessary to store the reagent tube 4, after placing the reagent tube 4 on the surface of the pressing plate 2655 through the hole groove 2611, press down the pressing plate 2655 to make the pressing plate 2655 drive the short column 2652 to descend. At this time, since the spherical ball 2653 is slidably connected to the threaded groove 2654, the movably arranged movable column 2651 will rotate. When the short column 2652 descends, the movable column 2651 will rotate. At this time, the rack B 2644 engaged with the tooth hole 2656 will move, causing the two clamping blocks 2641 to approach each other. At the same time as the pressing plate 2655 descends, the rolling ball 574 will move along the first chute 52. When the lower surface of the pressing plate 2655 contacts the movable column 2651, the short column 2652 has descended to the extreme, and the silica gel pad 2642 will also be deformed due to extrusion. At this moment, the T-shaped rod 573 will fall into the second chute 53. Subsequently, the force pressing the pressing plate 2655 can be released. When the pressing plate 2655 loses the downward pressure, the spring rod 2657 will drive the pressing plate 2655 to reset upward. However, when the pressing plate 2655 drives the fixing plate 51 to move upward, the T-shaped rod 573 will move along the second chute 53 into the third chute 54, thereby restricting the pressing plate 2655. The restricted pressing plate 2655 restricts the rotation of the movable column 2651, and further restricts the clamping block 2641. At this time, the restricted clamping block 2641 cooperates with the short column 2652 to clamp the reagent tube 4. The anti-slip property of the silica gel pad 2642 further improves the stability of the reagent tube 4 inside the outer shell 261. Since the steps of clamping the reagent tube 4 are completed in a very short time, the silica gel pad 2642 deformed due to extrusion will not damage the reagent tube 4. After the reagent tube 4 is placed, when the storage frame 2 is pushed into the inner cavity 11, the gear 263 on the outer surface of the bottom column 262 will engage with the rack A 15, thereby driving the outer shell 261 to rotate, and preliminarily mixing the samples inside the reagent tube 4. When the storage frame 2 completely enters the inner cavity 11, the reagent tube 4 will stop rotating. Until the storage frame 2 is pulled out again, the reagent tube 4 will rotate in the opposite direction again, so as to prevent the substances inside the reagent tube 4 from precipitating or stratifying, and finally improve the accuracy of subsequent detection. Embodiment

[0028] To solve the technical problem of how to further improve the subsequent detection effect, as Figures 1-5 and Figure 12 shown, the following preferred technical solutions are provided: A handle 22 is fixedly installed on one side of the storage box 2. On both sides of the storage box 2, baffles 21, T-shaped blocks 24 and cross plates 25 are fixedly installed. The baffle 21 is arranged on the side close to the handle 22, and the T-shaped block 24 and the cross plate 25 are arranged on the side far from the handle 22. The T-shaped block 24 is located below the cross plate 25. One end of the cross plate 25 is fixedly installed with a ladder plate 251. A rectangular plate 27 is fixedly installed on the upper surface of the storage box 2. There are four groups of rectangular plates 27, and two groups of rectangular plates 27 are respectively arranged on one side and the other side of the storage box 2. A bottom plate 23 is arranged on the lower surface of the storage box 2 close to the handle 22. The bottom plate 23 is adapted to the bottom groove 14. The cross plate 25 and the baffle 21 are on the same horizontal line. The length of the whole storage box 2 pulled out can be limited by the T-shaped block 24, and the outflow of the air inside the inner cavity 11 can be reduced by the baffle 21, the rectangular plate 27 and the bottom plate 23.

[0029] The reagent kit 1 is provided with a rectangular opening 12 and an inner groove 13. The inner cavity 11 is adapted to the rectangular plate 27, and the inner groove 13 is adapted to the baffle 21. The ladder plate 251 is movably connected to the inner groove 13 through the cross plate 25. A rectangular groove 16 is opened inside the reagent kit 1. A rod groove is opened at the bottom of the inner groove 13. The rectangular groove 16 is communicated with the inner groove 13 through the rod groove. A disinfection component 3 for disinfection and sterilization is fixedly installed on the surface of the reagent kit 1. A T-shaped groove 17 is opened on the inner wall of the inner cavity 11. The T-shaped groove 17 is slidably connected with the T-shaped block 24. When the storage box 2 is received into the inner cavity 11 through the inner cavity 11 and the rectangular plate 27, the bottom groove 14 and the bottom plate 23, and the inner groove 13 and the baffle 21, the loss of the gas inside the inner cavity 11 can be reduced. Then, the disinfection component 3 can spray the internal disinfectant into the inner cavity 11 in an atomized manner, so as to effectively eliminate all the bacteria brought inside the inner cavity 11 and from the outside. At this time, the stored storage box 2 can reduce the outflow of gas, thereby improving the disinfection effect. Existing reagent tubes 4 will be directly transported after being stored in the reagent kit. At this time, the bacteria in the outside air and the bacteria of the reagent kit itself will exist on the outer surface of the reagent tube 4, so that in the subsequent detection link, the bacteria will be mixed into the sample through the sampling link, interfering with the detection reaction.

[0030] The disinfection component 3 includes a temporary storage box 31 on the surface of the kit 1. A liquid box 32 is fixedly installed inside the rectangular groove 16. A liquid inlet pipe 33 is fixedly installed between the temporary storage box 31 and the liquid box 32. A spray pipe 34 is fixedly installed on one side of the liquid box 32. One end of the spray pipe 34 is inside the inner cavity 11. The spray pipe 34 is located above the storage frame 2. A pressing plate 35 is movably arranged inside the liquid box 32. A fixing rod 36 is fixedly installed on the lower surface of the pressing plate 35. The fixing rod 36 is adapted to the rod groove. By pressing the fixing rod 36, the fixing rod 36 drives the pressing plate 35 to rise, so that the disinfectant liquid inside the liquid box 32 is sprayed from the spray pipe 34 into the inner cavity 11, thereby disinfecting the inner cavity 11. Then, the disinfectant liquid can be replenished in time from the temporary storage box 31 through the liquid inlet pipe 33. Existing reagent tubes 4 are directly placed inside the storage plate and then directly transported waiting for detection, without performing the disinfection step. When separating the lid of the reagent tube 4 from the reagent tube 4, bacteria will enter the sample inside the reagent tube 4, thus interfering with the detection reaction.

[0031] A chute 37 is fixedly installed on the lower surface of the fixing rod 36. There are two groups of chutes 37, and both groups of chutes 37 are adapted to both sides of the ladder plate 251. When the storage frame 2 is pulled out from the inner cavity 11, the ladder plate 251 will move outwards from the inner wall of the inner groove 13. During a certain process, it will successively contact the fixing rod 36, so that one side of the ladder plate 251 contacts the chute 37 and pushes the fixing rod 36 upwards. At this time, the disinfectant liquid will be sprayed out in an atomized form from the spray pipe 34 to disinfect the inner cavity 11. When the storage frame 2 enters the inner cavity 11, it will also drive the fixing rod 36 to rise, disinfecting the inner cavity 11 again. During the transportation and use of existing kits, there is a lack of active disinfection measures for the internal environment, making it difficult to remove bacteria inside the kit. These bacteria are extremely likely to contaminate the reagent tube 4 and the sample, resulting in deviations in the test results.

[0032] Specifically, when the storage frame 2 is pulled out, one side of the ladder plate 251 will contact the chute 37 on the lower surface of the fixing rod 36. Since the ladder plate 251 can only move horizontally while the fixing rod 36 can move up and down, when the storage frame 2 is pulled out, the fixing rod 36 will be pushed upwards by the ladder plate 251. At this time, the moving fixing rod 36 will drive the pressing plate 35 to squeeze out the disinfectant liquid inside the liquid box 32. At this time, the spray pipe 34 will spray the disinfectant liquid in an atomized manner to disinfect the inner cavity 11. When the storage frame 2 is pushed into the inner cavity 11, spraying will be performed again. After the storage frame 2 is completely stored, the rectangular opening 12, the inner groove 13, and the bottom groove 14 will be sealed by the rectangular plate 27, the baffle 21, and the bottom plate 23 one by one, thereby reducing air fluidity and further improving the disinfection effect.

[0033] As described above, it is only the preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution and inventive concept of the present invention, making equivalent substitutions or changes should be covered within the protection scope of the present invention.

Claims

1. A kit for detecting myasthenia gravis antibodies, characterized in that, It includes a kit (1), inside which a storage frame (2) is movably arranged. Inside the storage frame (2), reagent tubes (4) are arranged. An inner cavity (11) is formed inside the kit (1), and a bottom groove (14) is formed at the bottom of the inner cavity (11). One end of the bottom groove (14) penetrates through one side of the kit (1), and a rack A (15) is fixedly installed on the inner wall of the bottom groove (14). Inside the storage frame (2), a fixing component (26) for fixing the reagent tubes (4) is movably arranged. The fixing component (26) includes a housing (261) movably arranged inside the storage frame (2). A bottom post (262) is fixedly installed on the lower surface of the housing (261). The bottom post (262) is movably connected to the bottom of the storage frame (2). One end of the bottom post (262) penetrates through the bottom of the storage frame (2). A gear (263) is sleeved on the outer surface of the bottom post (262). The gear (263) and the rack A (15) are on the same horizontal line, and the gear (263) meshes with the rack A (15). Inside the housing (261), a clamping component (264) for clamping the reagent tubes (4) is movably arranged. Inside the housing (261), a linkage component (265) for driving the clamping component (264) to clamp the reagent tubes (4) is arranged. A snap component (5) for fixing the position of the clamping component (264) is fixedly installed on the surface of the linkage component (265).

2. The kit for detecting myasthenia gravis antibodies according to claim 1, characterized in that: The linkage component (265) includes a movable column (2651) movably arranged inside the housing (261). A short column (2652) is movably arranged inside the movable column (2651). A spherical ball (2653) is fixedly installed on the outer surface of the short column (2652). A threaded groove (2654) is formed on the inner wall of the movable column (2651). The spherical ball (2653) is slidably connected to the threaded groove (2654). A pressing disc (2655) is fixedly installed on the upper surface of the short column (2652). The upper surface of the pressing disc (2655) is in contact with the lower surface of the reagent tube (4). A tooth hole (2656) is formed on the lower surface of the movable column (2651).

3. The kit for detecting myasthenia gravis antibodies according to claim 2, wherein: Two groups of clamping components (264) are provided. The two groups of clamping components (264) include clamping blocks (2641) movably arranged inside the housing (261). A silica gel pad (2642) is fixedly installed on one side of the clamping block (2641). A vertical rod (2643) is fixedly installed on the lower surface of the clamping block (2641). A rack B (2644) is fixedly installed on one side of the vertical rod (2643). Both groups of the racks B (2644) mesh with the tooth hole (2656), and the tooth hole (2656) is located between the two groups of the racks B (2644).

4. The kit for detecting myasthenia gravis antibodies according to claim 3, wherein: The surface of the housing (261) is provided with a hole groove (2611), the hole groove (2611) is located between two groups of the clamping blocks (2641), a block groove (2612) is provided inside the housing (261), the clamping blocks (2641) are slidably arranged in the block groove (2612), a vertical groove (2613) is provided at the bottom of the block groove (2612), the vertical groove (2613) is slidably connected with a vertical rod (2643), a disc groove (2614) is provided inside the housing (261), the disc groove (2614) is slidably connected with a pressure disc (2655), two groups of storage grooves (2615) are provided at the bottom of the disc groove (2614), the storage grooves (2615) are adapted to a buckle assembly (5), a column groove (2617) is further provided at the bottom of the disc groove (2614), the column groove (2617) is located between two groups of the storage grooves (2615), a horizontal groove (2616) is provided on the inner wall of the vertical groove (2613), the horizontal groove (2616) is communicated with the column groove (2617), a rack B (2644) is movably connected with the column groove (2617), the rack B (2644) is engaged with a tooth hole (2656) through the column groove (2617), a spring rod (2657) is fixedly installed on the lower surface of the pressure disc (2655), the lower surface of the spring rod (2657) is fixedly installed with the bottom of the column groove (2617), and the lower surface of the movable column (2651) is movably connected with the bottom of the column groove (2617).

5. The kit for detecting myasthenia gravis antibodies according to claim 4, wherein: The buckle assembly (5) includes a fixing plate (51) fixedly installed on the lower surface of the pressure disc (2655), a first chute (52), a second chute (53), a third chute (54) and a fourth chute (55) are provided on the surface of the fixing plate (51), the first chute (52) is lower than the fourth chute (55), the second chute (53) is lower than the first chute (52), the third chute (54) is lower than the second chute (53), a slope (56) is provided at one end of the fourth chute (55), one end of the slope (56) is in contact with one end of the third chute (54), a Z-shaped rod (57) is arranged inside the first chute (52), and the other end of the Z-shaped rod (57) is movably connected with the inner wall of the disc groove (2614).

6. The kit for detecting myasthenia gravis antibodies according to claim 5, wherein: A groove (571) is provided at one end of the Z-shaped rod (57), a return spring (572) is fixedly installed on the inner wall of the groove (571), a T-shaped rod (573) is arranged inside the groove (571), the return spring (572) is sleeved on the outer surface of the T-shaped rod (573), one end of the return spring (572) is fixedly connected with the inner wall of the groove (571), the other end of the return spring (572) is fixedly connected with one side of the T-shaped rod (573), and a rolling ball (574) is movably arranged at one end of the T-shaped rod (573).

7. The kit for detecting myasthenia gravis antibodies according to claim 1, characterized in that: One side of the storage box (2) is fixedly installed with a handle (22). Both sides of the storage box (2) are fixedly installed with a baffle (21), a T-shaped block (24) and a cross plate (25). The baffle (21) is arranged on the side close to the handle (22). The T-shaped block (24) and the cross plate (25) are arranged on the side far from the handle (22). The T-shaped block (24) is located below the cross plate (25). One end of the cross plate (25) is fixedly installed with a ladder plate (251). The upper surface of the storage box (2) is fixedly installed with a rectangular plate (27). There are four groups of the rectangular plates (27). Two groups of the rectangular plates (27) are respectively arranged on one side and the other side of the storage box (2). The lower surface of the storage box (2) close to the handle (22) is provided with a bottom plate (23). The bottom plate (23) is adapted to the bottom groove (14). The cross plate (25) and the baffle (21) are on the same horizontal line.

8. The kit for detecting myasthenia gravis antibodies according to claim 7, characterized in that: The kit (1) is provided with a rectangular opening (12) and an inner groove (13). The inner cavity (11) is adapted to the rectangular plate (27). The inner groove (13) is adapted to the baffle (21). The ladder plate (251) is movably connected to the inner groove (13) through the cross plate (25). A rectangular groove (16) is provided inside the kit (1). A rod groove is provided at the bottom of the inner groove (13). The rectangular groove (16) is communicated with the inner groove (13) through the rod groove. A disinfection component (3) for disinfection and sterilization is fixedly installed on the surface of the kit (1). A T-shaped groove (17) is provided on the inner wall of the inner cavity (11). The T-shaped groove (17) is slidably connected to the T-shaped block (24).

9. The kit for detecting myasthenia gravis antibodies according to claim 8, wherein: The disinfection component (3) includes a temporary storage box (31) on the surface of the kit (1). A liquid box (32) is fixedly installed inside the rectangular groove (16). A liquid inlet pipe (33) is fixedly installed between the temporary storage box (31) and the liquid box (32). A spray pipe (34) is fixedly installed on one side of the liquid box (32). One end of the spray pipe (34) is inside the inner cavity (11). The spray pipe (34) is located above the storage box (2). A pressing plate (35) is movably arranged inside the liquid box (32). A fixing rod (36) is fixedly installed on the lower surface of the pressing plate (35). The fixing rod (36) is adapted to the rod groove.

10. The kit for detecting myasthenia gravis antibodies according to claim 9, wherein: An inclined groove (37) is fixedly installed on the lower surface of the fixing rod (36). There are two groups of the inclined grooves (37). Both groups of the inclined grooves (37) are adapted to both sides of the ladder plate (251).

Citation Information

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