Anti-aging composition for strengthening skin supporting network and application of anti-aging composition

Abstract

The invention relates to an anti-aging composition for strengthening a skin supporting network and application thereof, and the anti-aging composition comprises the following components: a golden camellia flower extract, a saffron crocus extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside, the weight ratio of the golden camellia flower extract to the saffron crocus extract to the camellia seed oil to the tranexamic acid to the epigallocatechin gallate glucoside is (0.1 to 5) to (0.01 to 5) to (0.1 to 10) to (0.01 to 2) to (0.001 to 0.1). The composition provided by the invention can synergistically strengthen a skin support network and comprehensively improve skin elasticity and compactness by promoting growth of two core structural proteins and three macromolecular adhesives of skin, and is mild, non-irritant and suitable for people with sensitive skin.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to an anti-aging composition for strengthening the skin support network and application thereof. Background Art

[0002] The essence of skin aging is a decrease in the number of fibroblasts, loss of collagen, and disordered elastin fiber structure, which lead to a decline in skin barrier function, causing wrinkles, sagging, and other problems. Collagen is the main structural support of the skin (accounting for more than 70% of the dry weight of the dermis). Its loss leads to a decrease in the skin's tensile strength, causing wrinkles and sagging. The degradation of the elastin fiber network causes the skin to lose its resilience and aggravates sagging. The loss of core protein glycan, a "precision regulatory factor" of collagen fibers, directly disrupts the orderly arrangement of collagen fibers and weakens the dermal matrix's ability to resist deformation. The reduced expression of fibulin, the "assembly hub" of elastic fibers, prevents elastin from stably anchoring to the microfibril scaffold, causing the elastic network structure to collapse and impairing its repair function. Lysyl oxidase (LOX), the "cross-linking catalytic center" of the extracellular matrix, has a reduced activity that interferes with the covalent cross-linking of collagen / elastin, leading to a loosening and disintegration of the supporting structure. The synergistic attenuation and interactive disorder of these five types of proteins, by destroying the multi-level defense system of "collagen skeleton strength - elastic network toughness - fiber order - structural integrity - molecular stability", together constitute the molecular basis for the collapse of the skin support network, which ultimately manifests as a loss of skin elasticity and firmness.

[0003] Current anti-aging technologies primarily rely on bioactive ingredients (such as retinol and peptides) and plant extracts. However, the former suffer from poor stability and high irritation (for example, retinol is easily oxidized and can cause discomfort in sensitive skin), while the latter is limited in effectiveness due to the low transdermal absorption rate of natural ingredients. Despite the rise of emerging technologies (such as gene regulation and exosomes), their application is still limited by cost, regulations, and technological maturity. Furthermore, people with sensitive skin are more susceptible to inflammatory aging due to damaged skin barrier, and there is an urgent need for gentle and effective anti-aging solutions. Summary of the Invention

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art and provide an anti-aging composition for strengthening the skin support network and its application.

[0005] To achieve the above object, the technical solution adopted by the present invention is:

[0006] In a first aspect, the present invention provides an anti-aging composition for strengthening the skin support network, comprising the following components: camellia chrysantha extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside, wherein the weight ratio of the camellia chrysantha extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (0.1-5): (0.01-5): (0.1-10): (0.01-2): (0.001-0.1).

[0007] The mechanism of action of the components of the composition of the present invention is as follows: the golden camellia extract is rich in tea polyphenols, flavonol glycosides and proanthocyanidins, which scavenges free radicals through strong antioxidant effect, significantly improving skin roughness and photoaging damage; the saffron extract is rich in flavonoids and polyphenols, has a strong anti-inflammatory effect, and can effectively relieve skin redness and discomfort; the camellia seed oil contains high concentrations of oleic acid, vitamin E and squalene, simulates the sebum structure for deep penetration, enhances the water-locking ability and neutralizes free radicals, repairs stratum corneum damage, and delays wrinkle formation; the tranexamic acid (tranexamic acid) is a multifunctional skin care ingredient, which achieves whitening and soothing effects by strongly inhibiting tyrosinase activity and blocking inflammatory factors, and alleviates the premature aging symptoms caused by inflammation; epigallocatechin gallate glucoside is a polyphenol compound derived from green tea, with an antioxidant strength 25 times that of vitamin C, and blocks collagen degradation by inhibiting the activity of matrix metalloproteinases, thereby slowing down skin aging.

[0008] Preferably, the weight ratio of the Camellia chrysantha extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (0.5-3): (0.1-0.5): (1-3): (0.05-0.5): (0.01-0.05).

[0009] Preferably, the weight ratio of the Camellia chrysantha extract, Crocus saffron extract, Camellia seed oil, Tranexamic acid and Epigallocatechin Gallate Glucoside is (1-2): (0.2-0.3): (2-3): (0.1-0.2): (0.02-0.03).

[0010] Preferably, the total weight of the Camellia chrysantha extract and the Crocus sativus extract accounts for 35-45 wt % of the total weight of the anti-aging composition.

[0011] In a second aspect, the present invention provides use of the anti-aging composition for strengthening the skin support network in the first aspect in the preparation of cosmetics.

[0012] Preferably, the cosmetic is a lotion, emulsion, cream, facial mask, essence or spray, and the added amount of the anti-aging composition is 1%-5% of the total weight of the cosmetic.

[0013] In a third aspect, the present invention provides an essence comprising the following raw materials in weight percentage: 1%-5% of the anti-aging composition for strengthening the skin support network according to any one of claims 1 to 4, 0.05%-0.5% of a thickener, 0.5%-10% of a moisturizer, 0.5%-3% of a preservative and 0.01%-0.3% of a pH regulator, with the balance being deionized water.

[0014] Preferably, the thickener comprises at least one of xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyl taurate / VP copolymer and sclerotium gum.

[0015] Preferably, the moisturizing agent includes at least one of allantoin, betaine, β-glucan, trehalose, caprylyl glycol, dipropylene glycol, D-panthenol, sodium hyaluronate, 1,2-butylene glycol, glycerin, Pullulan and ceramide.

[0016] Preferably, the pH adjuster comprises at least one of arginine, tromethamine and EDTA-disodium.

[0017] Preferably, the preservative includes at least one of 1,3-propylene glycol, 1,2-hexanediol and p-hydroxyacetophenone.

[0018] In a fourth aspect, the present invention provides a method for preparing the essence of the third aspect, comprising the following steps:

[0019] S1. Mix a moisturizer, a thickener, and a portion of deionized water, homogenize at 75-85° C., add a preservative, and stir evenly to obtain a mixture;

[0020] S2. When the temperature of the mixture in S1 drops to 35-45° C., add the components of the anti-aging composition for strengthening the skin support network and the remaining deionized water, stir evenly, and finally add a pH regulator to adjust the pH to obtain the essence.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] The anti-aging composition of the present invention comprises camellia chrysantha extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside. Their synergistic effect can strengthen the skin's support network by promoting the growth of the skin's two core structural proteins and three molecular-level adhesives, thereby achieving a comprehensive improvement in skin elasticity and firmness. It is gentle and non-irritating, making it suitable for people with sensitive skin. DETAILED DESCRIPTION

[0023] In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0024] The sources of raw materials used in the following examples and comparative examples are as follows:

[0025] Camellia chrysantha extract: manufactured by Ximuyuan (Xiamen) Biotechnology Co., Ltd.

[0026] Tranexamic acid: The manufacturer is Shaanxi Wanhe Pharmaceutical Co., Ltd.

[0027] Camellia seed oil: manufactured by Biospectrum, South Korea;

[0028] Saffron extract: manufacturer is Guangzhou Youran Biotechnology Co., Ltd.

[0029] Epigallocatechin gallate glucoside: The manufacturer is Givaudan, Switzerland.

[0030] Unless otherwise specified, other materials and reagents used in the examples can be obtained from commercial sources.

[0031] Examples 1-7 and Comparative Examples 1-7

[0032] The components of the anti-aging compositions of Examples 1-7 and Comparative Examples 1-7 are shown in Table 1.

[0033] The preparation method of the anti-aging composition of Examples 1-7 and Comparative Examples 1-7 comprises the following steps:

[0034] The components were stirred and mixed at a rotation speed of 300 rpm to obtain the anti-aging composition.

[0035] Table 1 Data on the weight ratio of each component in each group of anti-aging compositions and the mass fraction of Camellia chrysantha extract and Saffron extract

[0036]

[0037] Test Example 1: Anti-aging composition promotes the synthesis of two core structural proteins and three adhesive proteins in the dermis

[0038] 1. Experimental Materials

[0039] 1. Cell line: Human dermal fibroblasts HDF (Cat. No. PC-202h, Wuhan Saios Biotechnology Co., Ltd.)

[0040] 2. Culture medium: DMEM high glucose culture medium containing 10% fetal bovine serum (Gibco)

[0041] 3. Inducer: PBS buffer containing 100 μM hydrogen peroxide

[0042] 4. Detection kit:

[0043] Human type I collagen (Col I) ELISA kit (catalog number ml057630, Shanghai ELISA) Human elastin ELISA kit (catalog number ml038411, Shanghai ELISA)

[0044] Human Decorin (DCN) ELISA Kit (Cat. No. ml105251, Shanghai ELISA Biotechnology Co., Ltd.)

[0045] Human senescence key protein 1 (FBLN1) ELISA kit (catalog number ml037827, Shanghai ELISA Biotechnology)

[0046] Human lysyl oxidase (LOX) ELISA kit (catalog number ml105166, Shanghai ELISA Biotechnology Co., Ltd.)

[0047] 2. Test conditions

[0048] The incubator parameters were set as temperature 37 ± 1 °C, humidity 90 ± 5%, and carbon dioxide concentration 5 ± 1%.

[0049] 3. Test steps

[0050] 1. Cell seeding

[0051] Human dermal fibroblasts (HDFs) were cultured at a rate of 1.5 × 10 5 Cells were seeded at a density of 100 cells / mL into a 12-well cell culture plate, and 1 mL of DMEM high-glucose culture medium (Gibco) containing 10% fetal bovine serum was added to each well. The culture plate was placed in a pre-set incubator and incubated at 37°C and 5% CO2 for 24 hours.

[0052] 2. Cell induction

[0053] After 24 hours of incubation, discard the culture medium from the plate. Add pre-prepared PBS buffer containing 100 μM hydrogen peroxide and allow the cells to incubate for 30 minutes. After treatment, discard the PBS solution containing hydrogen peroxide. Gently rinse the plate three times with PBS buffer to remove any residual hydrogen peroxide.

[0054] 3. Sample processing

[0055] For the blank control group, three parallel wells were set up, and 1 mL of DMEM high-glucose culture medium containing 10% fetal bovine serum was added to each well.

[0056] For each sample group, three parallel wells were set up, and an equal volume of DMEM high-glucose culture medium containing 10% fetal bovine serum and 0.05 wt% of the anti-aging composition of each group was added to each well. After sampling, the culture plates of each group were returned to the incubator and cultured for another 24 hours at 37°C and 5% CO2.

[0057] 4. Collection of supernatant

[0058] After 24 hours of incubation, each culture plate was removed from the incubator, the cells were harvested, and the supernatant discarded. The cells were lysed using RIPA lysis buffer (Merck, Shanghai, V900854) containing protease inhibitors. The lysed samples were centrifuged at 12,000 g for 5 minutes, and the supernatant was collected and stored below 4°C for subsequent component content analysis.

[0059] 5. Detection of content of each ingredient

[0060] Type I collagen content detection: According to the instructions of the human type I collagen (Col I) ELISA kit (catalog number ml057630, Shanghai ELISA Biotechnology), equal amounts of cell culture supernatant from the blank control group and sample group were added to the corresponding reaction wells of the kit. After incubation, washing, color development and other steps, the absorbance value was measured at a specific wavelength using a microplate reader, and the type I collagen content in each group was calculated according to the standard curve.

[0061] Elastin content detection: According to the instructions of the human elastin ELISA kit (catalog number ml038411, Shanghai ELISA Biotechnology), equal amounts of cell culture supernatant from the blank control group and sample group were taken for detection. The elastin content of each group was obtained by strictly following the kit operating procedures.

[0062] Decorin content detection: Human Decorin (DCN) ELISA kit (catalog number ml105251, Shanghai ELISA Biotechnology) was used to detect equal amounts of cell culture supernatant of the blank control group and sample group. The kit operation procedures were strictly followed to finally obtain the decorin content of each group.

[0063] Detection of fibula protein content: Human aging key protein 1 (FBLN1) ELISA kit (catalog number ml037827, Shanghai ELISA Biotechnology) was used for detection. Equal amounts of cell culture supernatant from the blank control group and sample group were taken for determination. The fibula protein content was calculated strictly according to the kit operating procedures.

[0064] Lysyl oxidase content detection: Human lysyl oxidase (LOX) ELISA kit (catalog number ml105166, Shanghai ELISA Biotechnology) was used to detect equal amounts of cell culture supernatant of the blank control group and sample group. The lysyl oxidase content of each group was obtained by strictly following the kit operating procedures.

[0065] 4. Calculation of anti-aging ability of anti-aging composition

[0066] The increase rates of type I collagen, elastin, decorin, fibulin, and lysyl oxidase were calculated according to the following formulas to evaluate the anti-aging ability of the anti-aging composition:

[0067] Type I collagen increase rate = (Type I collagen content 样品组 / Type I collagen content 对照组 )×100%-1;

[0068] Elastin increase rate = (elastin content 样品组 / Elastin content 对照组 )×100%-1;

[0069] Decorin increase rate = (Decorin content 样品组 / Decorin content 对照组 )×100%-1;

[0070] Peroneal protein increase rate = (peroneal protein content 样品组 / Fibula protein content 对照组 )×100%-1;

[0071] Lysyl oxidase increase rate = (lysyl oxidase content 样品组 / Lysyl oxidase content 对照组 )×100%-1. See Table 2 for data.

[0072] Table 2 Experimental data on the anti-aging ability of the anti-aging compositions of each group

[0073]

[0074]

[0075] Collagen and elastin are the two core structural proteins of the skin. Collagen is the skin's "reinforcing skeleton," forming a meshwork of fibers that provides tensile strength and support. Elastin forms a network of elastic fibers that supports the collagen skeleton and provides instantaneous rebound. Decorin, fibulin, and lysyl oxidase serve as three molecular adhesives, strengthening the skin's support network. Decorin wraps around collagen fibers, regulating their orderly arrangement and diameter uniformity, enhancing tensile strength. Fibulin anchors elastin to microfibrils, weaving a dense elastic fiber network that prevents elastic fiber breakage and dispersion, enhancing the stability of the network structure. Lysyl oxidase catalyzes the cross-linking reaction between collagen and elastin, forming covalent "welds," strengthening the collagen-elastin complex structure and resisting enzymatic and mechanical damage.

[0076] From the data of Example 1 and Comparative Examples 1-2 in Table 2, it can be seen that when the weight ratio of Camellia chrysantha extract, Crocus saffron extract, Camellia seed oil, Tranexamic acid, and Epigallocatechin Gallate Glucoside in the composition is not in the range of (0.1-5): (0.01-5): (0.1-10): (0.01-2): (0.001-0.1), the increase rate of each protein is significantly reduced.

[0077] From the data of Example 1 and Comparative Examples 3-7 in Table 2, it can be seen that the composition of Example 1, which is a compound of the five ingredients of Camellia chrysantha extract, Saffron extract, Camellia seed oil, Tranexamic acid and Epigallocatechin Gallate Glucoside, has a significant promoting effect on the production of type I collagen, elastin, decorin, fibulin and lysyl oxidase, which indicates that the five ingredients have a synergistic effect to improve the anti-aging effect of the composition.

[0078] It can be seen from the data of Example 1 and Examples 4-7 in Table 2 that when the weight ratio of Camellia chrysantha extract, Crocus sativus extract, Camellia seed oil, Tranexamic acid and Epigallocatechin Gallate Glucoside is (1-2): (0.2-0.3): (2-3): (0.1-0.2): (0.02-0.03) and the total mass of the Camellia chrysantha extract and the Crocus sativus extract accounts for 35-45wt% of the total mass of the anti-aging composition, the effect of the composition in promoting protein production is at a better level.

[0079] Application Examples 1-7 and Comparative Application Examples 1-7

[0080] The compositions of Examples 1-7 and Comparative Examples 1-7 were added to the essence at a concentration of 3 wt %, respectively, to obtain the essences of Application Examples 1-7 and Comparative Application Examples 1-7. The formulas are shown in Table 3.

[0081] The preparation method of the essence of Application Examples 1-7 and Comparative Application Examples 1-7 comprises the following steps:

[0082] S1. Mix the moisturizer, thickener, and 1 / 2 amount of deionized water, and homogenize at 80° C. to obtain a mixed solution;

[0083] S2. When the temperature of the mixed solution in S1 drops to 60° C., add a preservative. When the system temperature drops to 40° C., add each component in the composition and the remaining deionized water, stir evenly, and finally add a pH adjuster to adjust the pH to 6 to obtain the essence.

[0084] Table 3 Essence formula of application examples 1-7 and comparative application examples 1-7

[0085]

[0086]

[0087] Comparative Application Example 8

[0088] The essence of comparative application example 8 does not contain the anti-aging composition for strengthening the skin support network, and uses an equal amount of deionized water instead of the composition. The preparation method is the same as that of application example 1.

[0089] Test Example 2: Human Patch Test of Essence

[0090] Thirty volunteers (15 men and 15 women, aged 20-50 years) were recruited and tested using a closed patch test method. Equal amounts (0.020 mL to 0.025 mL) of test samples (the essences prepared in Application Examples 1-7 and Comparative Application Examples 1-8) were placed in a specific patch tester. These were then applied to the volunteers' arms using hypoallergenic tape. Nine groups of test samples were applied to each arm, with gentle pressure applied to evenly distribute the samples. The patches were left on for 24 hours. After 24 hours, the patch testers were removed, and skin reactions were observed 0.5, 24, and 48 hours later, with the results recorded. The levels of adverse skin reactions are shown in Table 4 below.

[0091] Table 4 Grades of adverse skin reactions

[0092]

[0093] After testing, the essences provided in Application Examples 1-7 and Comparative Application Examples 1-8 all showed negative reactions after human patch tests, indicating that they are safe and non-irritating to human skin.

[0094] Test Example 3: Anti-aging efficacy test of serum on human body

[0095] 1. Experimental basis

[0096] Refer to the human efficacy evaluation test method in the "Technical Specifications for Safety of Cosmetics" (2015 edition) for implementation.

[0097] 2. Subject screening

[0098] Inclusion criteria: Asian female volunteers aged 45-60 years old who meet the following conditions:

[0099] a) Clinical assessment of skin laxity (grade I-III according to the clinical grading standard);

[0100] b) Self-reported history of skin sensitivity (confirmed by dermatologist evaluation);

[0101] c) No history of severe systemic disease or skin disease.

[0102] Exclusion criteria: pregnant / lactating women, people with severe allergies, and those who have participated in other clinical trials in the past 3 months.

[0103] Number setting: A total of 90 qualified volunteers were included and divided into 15 groups according to the random number table method, with 6 people in each group.

[0104] 3. Sample application method

[0105] Test samples: essences prepared in Application Examples 1-7 and Comparative Application Examples 1-8 (double-blind numbering), wherein the essence prepared in Comparative Application Example 8 was the blank control group, and the remaining application examples and comparative application examples were sample groups.

[0106] Usage: After cleansing every morning and evening, volunteers take 1mL of the sample and apply it evenly on the entire face, gently massaging until completely absorbed.

[0107] 4. Testing cycle and process

[0108] Test period: 28 days (D0 to D 28 ).

[0109] Visit time points: D0 (baseline period) and D 28 (Test endpoint) Perform instrument detection.

[0110] Preparation before testing:

[0111] a) After the visit, the subjects cleansed their faces with a uniform non-irritating cleansing product;

[0112] b) Keep the specimen in a constant temperature and humidity environment (temperature 21±1°C, humidity 50±10%) for 30 minutes;

[0113] c) Keep your eyes closed and relaxed during the test to avoid interference from facial expressions and movements.

[0114] 5. Test instruments and parameters

[0115] Instrument: Cutometer (MPA580, Courage and Khazaka, Germany) was used.

[0116] Measuring site: Cheek (avoiding the orbital and lip areas).

[0117] Operation process:

[0118] The instrument was calibrated to standard parameters; the probe pressure and measurement time were fixed; the measurement was repeated three times at the same location and the average value was taken.

[0119] The skin tightening effect is represented by the improvement of the firmness F4 value, and the skin elasticity enhancement effect is represented by the improvement of the elasticity parameter R2 value. The formula is as follows:

[0120] F4 value improvement rate = (F4 T0 -F4 T28 ) / F4 T0×100%;

[0121] R2 value improvement rate = (R2 T0 -R2 T28 ) / R2 T0 ×100%. See Table 5 for data.

[0122] Table 5 Human efficacy test results of each group of essences

[0123] sample F4 value improvement rate / % R2 value improvement rate / % Application Example 1 24.8 28.6 Application Example 2 23.2 27.5 Application Example 3 19.1 25.3 Application Example 4 18.7 25.6 Application Example 5 17.3 21.5 Application Example 6 16.9 20.8 Application Example 7 20.6 26.9 Comparative Application Example 1 3.4 4.6 Comparative Application Example 2 5.8 8.6 Comparative Application Example 3 2.6 2.8 Comparative Application Example 4 7.7 9.9 Comparative Application Example 5 5.1 7.7 Comparative Application Example 6 6.4 9.0 Comparative Application Example 7 4.6 6.8 Comparative Application Example 8 (Blank Control Group) 0.6 0.3

[0124] F4 (Firmness) reflects the combined effect of skin resilience and firmness; a higher value indicates greater firmness. R2 (Elasticity) measures the ratio of skin's rebound capacity to its maximum stretch when no negative pressure is applied; a higher value indicates greater elasticity.

[0125] It can be seen from the data of Application Example 1 and Comparative Application Examples 1-2 in Table 4 that if the weight ratio of the Camellia chrysantha extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside in the essence composition is not within the range of (0.1-5):(0.01-5):(0.1-10):(0.01-2):(0.001-0.1), the skin firmness and elasticity are significantly reduced.

[0126] From the data of Application Example 1 and Comparative Application Examples 3-7 in Table 4, it can be seen that the composition of Example 1, which is a compound of five ingredients including Camellia chrysantha extract, Saffron extract, Camellia seed oil, Tranexamic acid, and Epigallocatechin Gallate Glucoside, has a significantly improved effect on enhancing skin elasticity and improving skin firmness compared with the compositions of Comparative Examples 3-7, indicating that the anti-aging composition of the present invention synergistically strengthens the skin support network and achieves a comprehensive improvement in skin elasticity and firmness.

[0127] Combined with the data of Application Examples 1-7, it can be seen that when the weight ratio of Camellia chrysantha extract, Crocus sativus extract, Camellia seed oil, Tranexamic acid and Epigallocatechin Gallate Glucoside is (1-2): (0.2-0.3): (2-3): (0.1-0.2): (0.02-0.03) and the total mass of the Camellia chrysantha extract and the Crocus sativus extract accounts for 35-45wt% of the total mass of the anti-aging composition, the anti-aging performance of the composition is better.

[0128] In summary, the anti-aging composition of the present invention, through the synergistic effect of five ingredients, namely, Camellia chrysantha extract, Saffron extract, Camellia seed oil, Tranexamic acid, and Epigallocatechin Gallate Glucoside, strengthens the skin's support network by promoting the growth of two core structural proteins and three molecular-level adhesives of the skin, thereby achieving a comprehensive improvement in skin elasticity and firmness. It is gentle and non-irritating, and is suitable for people with sensitive skin.

[0129] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. An anti-aging composition for strengthening the skin support network, characterized in that: The invention comprises the following components: golden camellia extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside, wherein the weight ratio of the golden camellia extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (0.1-5): (0.01-5): (0.1-10): (0.01-2): (0.001-0.1).

2. The anti-aging composition for strengthening the skin support network according to claim 1, characterized in that: The weight ratio of the camellia chrysantha extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (0.5-3): (0.1-0.5): (1-3): (0.05-0.5): (0.01-0.05).

3. The anti-aging composition for strengthening the skin support network according to claim 1, characterized in that: The weight ratio of the camellia chrysantha extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (1-2): (0.2-0.3): (2-3): (0.1-0.2): (0.02-0.03).

4. The anti-aging composition for strengthening the skin support network according to claim 1, characterized in that: The total weight of the Camellia chrysantha extract and the Crocus sativus extract accounts for 35-45 wt % of the total weight of the anti-aging composition.

5. Use of the anti-aging composition for strengthening the skin support network according to any one of claims 1 to 4 in the preparation of cosmetics.

6. Use of the anti-aging composition for strengthening the skin support network according to claim 5 in the preparation of cosmetics, characterized in that: The cosmetics are lotions, emulsions, creams, facial masks, essences or sprays, and the added amount of the anti-aging composition is 1%-5% of the total weight of the cosmetics.

7. An essence, characterized in that: The invention comprises the following raw materials in weight percentage: 1%-5% of the anti-aging composition for strengthening the skin support network according to any one of claims 1 to 4, 0.05%-0.5% of a thickener, 0.5%-10% of a moisturizer, 0.5%-3% of a preservative, and 0.01%-0.3% of a pH regulator, with the balance being deionized water.

8. The essence according to claim 7, characterized in that The raw material is selected from at least one of (a) to (d): (a) the thickener comprises at least one of xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyl taurate / VP copolymer, and sclerotium gum; (b) the moisturizing agent comprises at least one of allantoin, betaine, β-glucan, trehalose, caprylyl glycol, dipropylene glycol, D-panthenol, sodium hyaluronate, 1,2-butylene glycol, glycerin, budding pullulan polysaccharide and ceramide; (c) the pH adjusting agent comprises at least one of arginine, tromethamine and EDTA-disodium; (d) The preservative includes at least one of 1,3-propylene glycol, 1,2-hexanediol and p-hydroxyacetophenone.

9. The method for preparing the essence according to claim 8, characterized in that: The following steps are involved: S1. Mix a moisturizer, a thickener, and a portion of deionized water, homogenize at 75-85° C., add a preservative, and stir evenly to obtain a mixture; S2. When the temperature of the mixture in S1 drops to 35-45° C., add the components of the anti-aging composition for strengthening the skin support network and the remaining deionized water, stir evenly, and finally add a pH regulator to adjust the pH to obtain the essence.

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