Instant blood glucose automatic detection equipment based on enzyme electrode biosensor

Abstract

The invention relates to the technical field of medical instruments, in particular to instant blood glucose automatic detection equipment based on an enzyme electrode biosensor, which comprises a blood glucose meter main body, a sample frame is mounted in the blood glucose meter main body, a lifting mechanism is mounted in the blood glucose meter main body, and a sampling needle is mounted on the lifting mechanism. The detection equipment disclosed by the invention is based on the enzyme electrode biosensor, the detection method is accurate and reliable, the measurement range is 0.5-50mmo l / L (9-900mg / dL) of glucose, the repeatability and the accuracy are high, clinical detection requirements can be met, the equipment realizes an automatic detection process, the operation is simple and convenient, manual operation errors are reduced, the detection efficiency is improved, the equipment is suitable for being used by medical institutions and families, and the method is worthy of popularization and application. A perfect safety protection mechanism and a maintenance system are provided, safe operation and long-term stability of equipment are guaranteed, the use risk is reduced, an operation interface is friendly, functions are rich, and a user can conveniently carry out detection operation, data management and equipment setting.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to an instant automatic blood glucose detection device based on an enzyme electrode biosensor. Background Art

[0002] Currently, blood glucose testing is crucial for the monitoring and treatment of diabetic patients. Traditional blood glucose testing methods have problems such as complex operation, long testing time, and the need for professional operation, which cannot meet patients' needs for immediate and convenient testing. Some existing point-of-care testing devices have shortcomings in detection accuracy, sample handling convenience, device stability, and user-friendly interface, making it difficult to achieve efficient, accurate, and easy-to-use automatic blood glucose testing. To this end, a point-of-care blood glucose automatic testing device based on an enzyme electrode biosensor is proposed. Summary of the Invention

[0003] In view of this, the present invention provides an instant automatic blood glucose detection device based on an enzyme electrode biosensor to solve or alleviate the technical problems existing in the prior art and at least provide a beneficial option.

[0004] The technical solution of the present invention is implemented as follows: an instant blood glucose automatic detection device based on an enzyme electrode biosensor includes a blood glucose meter body, a sample rack is installed inside the blood glucose meter body, a lifting mechanism is installed inside the blood glucose meter body, a sampling needle is installed on the lifting mechanism, a flushing valve is installed below the sampling needle, a biosensor is installed inside the blood glucose meter body, and a peristaltic pump is installed inside the blood glucose meter body on one side of the biosensor.

[0005] Further preferably, a waste liquid bottle and a cleaning liquid bottle are respectively installed inside the blood glucose meter body, and the peristaltic pump is connected to the waste liquid bottle and the cleaning liquid bottle respectively through pipelines.

[0006] Further preferably, a control panel is installed on the top of the blood glucose meter body.

[0007] Further preferably, a cover is hingedly connected to the top of the blood glucose meter body on one side of the control panel.

[0008] Further preferably, a light strip is installed on the front surface of the blood glucose meter body.

[0009] Further preferably, an interface is installed on the rear surface of the blood glucose meter body.

[0010] The embodiment of the present invention adopts the above technical solution, which has the following advantages:

[0011] The detection device of the present invention is based on an enzyme electrode biosensor, and the detection method is accurate and reliable. The measurement range is 0.5-50mmol / L (9-900mg / dL) of glucose, with high repeatability and accuracy, which can meet clinical detection needs. The device realizes an automated detection process, is simple and convenient to operate, reduces human operation errors, and improves detection efficiency. It is suitable for use in medical institutions and homes, and has a complete safety protection mechanism and maintenance system to ensure the safe operation and long-term stability of the equipment, reduce the risk of use, and has a user-friendly operation interface and rich functions, which facilitates users to perform detection operations, data management and equipment settings.

[0012] The above summary is for illustrative purposes only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the present invention will be readily apparent by reference to the accompanying drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without any creative work.

[0014] Figure 1 It is a structural diagram of the present invention;

[0015] Figure 2 Another structural diagram of the present invention;

[0016] Figure 3 This is another structural diagram of the present invention.

[0017] Figure numerals: 1. Blood glucose meter body; 2. Sample rack; 3. Lifting mechanism; 4. Sampling needle; 5. Flush valve; 6. Biosensor; 7. Peristaltic pump; 8. Waste liquid bottle; 9. Cleaning liquid bottle; 10. Control panel; 11. Cover; 12. Light strip; 13. Interface. DETAILED DESCRIPTION

[0018] Hereinafter, only certain exemplary embodiments are briefly described. As will be appreciated by those skilled in the art, the described embodiments may be modified in various ways without departing from the spirit or scope of the present invention. Therefore, the drawings and description are to be considered as illustrative in nature and not restrictive.

[0019] The embodiments of the present invention are described in detail below with reference to the accompanying drawings.

[0020] like Figure 1-3As shown, an embodiment of the present invention provides an instant blood glucose automatic detection device based on an enzyme electrode biosensor, including a blood glucose meter body 1, a sample rack 2 is installed inside the blood glucose meter body 1, a lifting mechanism 3 is installed inside the blood glucose meter body 1, a sampling needle 4 is installed on the lifting mechanism 3, a flushing valve 5 is installed below the sampling needle 4, a biosensor 6 is installed inside the blood glucose meter body 1, and a peristaltic pump 7 is installed on one side of the biosensor 6 inside the blood glucose meter body 1.

[0021] In one embodiment, a waste liquid bottle 8 and a cleaning liquid bottle 9 are respectively installed inside the blood glucose meter body 1, and the peristaltic pump 7 is connected to the waste liquid bottle 8 and the cleaning liquid bottle 9 through pipelines; by squeezing the pipeline, liquid flow power is provided to the instrument pipeline system, so that the cleaning liquid, sample, waste liquid and other system liquids reach the designated position. The pump tube of the peristaltic pump 7 is connected to the cleaning liquid bottle 9 and the waste liquid bottle 8, controls the fluid system of the instrument, extracts cleaning liquid to clean the instrument system, and transports the waste liquid to the waste liquid bottle 8.

[0022] In one embodiment, a control panel 10 is installed on the top of the blood glucose meter body 1; the control panel 10 is provided with explanations and instructions of the daily operation process of the blood glucose meter body 1 and is displayed in the form of color pictures to avoid the situation where the blood glucose meter body 1 cannot be used due to the change of operators. It is used to display test results, change the target value, range, manufacturer and batch number information of the quality control solution, and count internal quality control results, and automatically calculate the mean, standard deviation, CV value, variance, etc.

[0023] In one embodiment, a cover 11 is hingedly connected to the top of the blood glucose meter body 1 on one side of the control panel 10; when the cover 11 is not closed, the instrument cannot detect, and the lifting mechanism 3 may pinch the risk of the cover being designed to avoid such risks.

[0024] In one embodiment, a light strip 12 is installed on the front surface of the blood glucose meter body 1; through the setting of the light strip 12, the white light indicates that the blood glucose meter body 1 is ready, the blue light indicates that the machine is running, and the red light indicates a machine error or failure.

[0025] In one embodiment, an interface 13 is installed on the rear surface of the blood glucose meter body 1; the interface 13 includes RS232, USB, RJ45 network ports and power input, and can be connected to the information system through the RS232 or RJ45 in the interface 13 to support HL7 and ASTM protocols.

[0026] When the present invention is working: select a suitable location, the working temperature is +15 to +35°C, the storage temperature is -20 to +35°C, the relative humidity is 20 to 95%, avoid direct sunlight, strong electromagnetic fields and ionizing radiation, and place it horizontally on the laboratory workbench. When connecting the main power supply, pull the lock on the power plug back and connect it to the power interface 13 of the blood glucose meter body 1, and then connect it to the main socket. The blood glucose meter body 1 automatically starts, opens the protective cover, places the enzyme electrode biosensor 6, installs the pump tube, places the cleaning liquid bottle 9 and the waste liquid bottle 8 in steps, uses the enzyme electrode biosensor 6 as the core detection element, and starts the detection by clicking the control panel 10. The control panel 10 will display the real-time detection status, the sample rack 2 will move to the lifting mechanism 3, and the sensor will detect whether the reagent cup exists and whether there is liquid. The lifting mechanism 3 takes samples and the peristaltic pump 7 rotates and squeezes to bring the collected whole blood sample into contact with the sensor. The glucose in the sample undergoes a chemical reaction under the catalysis of the enzyme. In this process, an electrical signal related to the glucose concentration is generated. Its sensitivity is 0.5-3.0nA / mmol / L, which can accurately sense changes in glucose concentration and quickly generate corresponding electrical signals. The response time is less than 6s, providing an initial data basis for subsequent detection. After the detection module obtains the electrical signal generated by the enzyme electrode biosensor 6, it transmits it to the data processing module. The data processing module uses a specific algorithm to amplify, filter, and perform analog-to-digital conversion on the electrical signal to remove interference signals and convert the analog signal into a digital signal, which is convenient for subsequent precise analysis and calculation, and thus obtains an accurate blood glucose concentration value.

[0027] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any person skilled in the art can easily conceive of various modifications and substitutions within the technical scope disclosed in the present invention, and such modifications and substitutions are intended to be within the scope of protection of the present invention. Therefore, the scope of protection of the present invention shall be subject to the scope of protection of the claims.

Claims

1. An automatic blood glucose detection device based on an enzyme electrode biosensor, characterized by: The invention comprises a blood glucose meter body (1), a sample rack (2) is installed inside the blood glucose meter body (1), a lifting mechanism (3) is installed inside the blood glucose meter body (1), a sampling needle (4) is installed on the lifting mechanism (3), a flushing valve (5) is installed below the sampling needle (4), a biosensor (6) is installed inside the blood glucose meter body (1), and a peristaltic pump (7) is installed inside the blood glucose meter body (1) on one side of the biosensor (6).

2. The instant automatic blood glucose detection device based on enzyme electrode biosensor according to claim 1, characterized in that: A waste liquid bottle (8) and a cleaning liquid bottle (9) are respectively installed inside the blood glucose meter body (1), and the peristaltic pump (7) is respectively connected to the waste liquid bottle (8) and the cleaning liquid bottle (9) through pipelines.

3. The instant automatic blood glucose detection device based on enzyme electrode biosensor according to claim 1, characterized in that: A control panel (10) is installed on the top of the blood glucose meter body (1).

4. The instant automatic blood glucose detection device based on enzyme electrode biosensor according to claim 3, characterized in that: A cover plate (11) is hingedly connected to the top of the blood glucose meter body (1) on one side of the control panel (10).

5. The instant automatic blood glucose detection device based on enzyme electrode biosensor according to claim 1, characterized in that: A light strip (12) is installed on the front surface of the blood glucose meter body (1).

6. The instant automatic blood glucose detection device based on enzyme electrode biosensor according to claim 1, characterized in that: An interface (13) is installed on the rear surface of the blood glucose meter body (1).

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