Traditional Chinese medicine composition, traditional Chinese medicine preparation and traditional Chinese medicine patch for diminishing swelling, removing stasis, relieving stuffy nose and inducing resuscitation as well as preparation method and application

Abstract

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition, a traditional Chinese medicine preparation, a traditional Chinese medicine patch, a preparation method and application for reducing swelling, removing stasis, relieving stuffy nose and inducing resuscitation, and the traditional Chinese medicine composition for reducing swelling, removing stasis, relieving stuffy nose and inducing resuscitation is characterized by being prepared from the following traditional Chinese medicinal materials in parts by weight: 0.5-1.2 parts of herba asari; 0.5 to 1.2 parts by weight of semen brassicae; 0.5 to 1.2 parts by weight of dahurian angelica root; 1.5 to 3.6 parts by weight of carapace; and 0.5-1.2 parts by weight of Sichuan lovage rhizome. The traditional Chinese medicine composition can effectively prevent and / or treat infantile adenoid hypertrophy, and is simple in components, low in toxic and side effects, safe and reliable.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition, a traditional Chinese medicine preparation, a traditional Chinese medicine patch, a preparation method and an application thereof for reducing swelling, dispersing nodules and clearing the nose and opening the orifices. Background Art

[0002] Adenoid hypertrophy often manifests as nasal congestion, a nasal sound during speech, snoring during sleep, and severe apnea caused by breath holding. It often leads to secretory otitis media, tinnitus, and hearing loss. If left untreated for a long time, adenoid facies may develop. Adenoid hypertrophy is associated with repeated inflammatory stimulation, such as acute and chronic rhinitis, tonsillitis, and influenza, which can cause pathological adenoid hyperplasia. In addition, allergic reactions, endocrine disorders, and malnutrition can also contribute to adenoid hypertrophy.

[0003] Currently, the treatments for adenoid hypertrophy usually include general treatment, Western medicine treatment, surgical treatment, radiotherapy and traditional Chinese medicine treatment. Among them:

[0004] In terms of general treatment, if the patient with adenoid hypertrophy does not have obvious symptoms of discomfort and the condition is relatively mild, special treatment is usually not required. He should pay attention to a light diet and eat more fruits and vegetables rich in dietary fiber, such as apples, spinach, etc., to supplement the nutrients needed by the body.

[0005] In terms of Western medicine treatment, if patients experience nasal congestion, they can use drugs such as oxymetazoline hydrochloride nasal drops and xylometazoline hydrochloride nasal drops under the guidance of a doctor to effectively control the disease. If an infection occurs, antibiotics such as cefixime granules and amoxicillin granules can be used as prescribed by the doctor.

[0006] In terms of surgical treatment, if the patient's condition is serious and adenoids hypertrophy occurs, accompanied by symptoms such as sore throat and difficulty swallowing, the disease can be effectively controlled through related surgeries such as adenoidectomy.

[0007] In terms of radiotherapy, it is suitable for patients who are unwilling or unsuitable for surgery. High-temperature rays can be used to kill adenoid tissue, thereby achieving the purpose of treatment.

[0008] In Traditional Chinese Medicine (TCM), adenoid hypertrophy is believed to be caused by insufficient vital energy and a weakened defense system, allowing pathogenic qi to invade, leading to upward lung qi reversal and nasal obstruction, resulting in nasal congestion and mouth breathing. Under the guidance of a physician, patients can undergo acupuncture treatment at points such as Tiantu, Dazhui, and Quchi, which can dispel wind and relieve exterior symptoms, and promote lung function and clear the orifices. Oral decoctions, based on syndrome differentiation and treatment, utilize prescriptions that dispel wind, activate blood circulation, clear the orifices, and reduce swelling and resolve stagnation. Examples include Yinqiao Powder for wind-evil invading the lungs, Erchen Decoction for phlegm blocking the orifices, and Tongqiao Huoxue Decoction for blood stasis blocking the orifices.

[0009] The above general treatment methods are not significantly effective and may easily lead to further development of the disease. Western medicine and radiotherapy have large toxic side effects, and surgical treatment causes greater damage to the patient's body. Acupuncture and oral decoction treatments in traditional Chinese medicine are not easily accepted by children, resulting in poor efficacy.

[0010] In view of this, the present invention is proposed. Summary of the Invention

[0011] In order to overcome the deficiencies in the above-mentioned prior art, the present invention provides a Chinese medicine composition, a Chinese medicine preparation, a Chinese medicine patch, a preparation method and an application thereof for reducing swelling, dispersing nodules and clearing the nose and opening the orifices.

[0012] A first aspect of the present invention provides a traditional Chinese medicine composition for reducing swelling, dispersing nodules, and clearing the nose and opening the orifices. The traditional Chinese medicine composition comprises the following traditional Chinese medicines in parts by weight:

[0013]

[0014]

[0015] The detailed pharmacology of the above components are as follows:

[0016] Asarum: Pungent, warm, enters the Heart, Lung, and Kidney meridians. It relieves exterior symptoms, dispels cold, dispels wind and relieves pain, opens the orifices, warms the lungs and transforms fluid. It is used for colds, headaches, toothaches, rheumatic pain, sinusitis, and lung-cold coughs.

[0017] Angelica dahurica: Pungent in flavor, warm in nature, enters the lung, spleen, and stomach meridians. It relieves exterior symptoms, dispels cold, dispels wind and relieves pain, clears the nasal passages, dries dampness and stops leukorrhea, reduces swelling and discharges pus, dispels wind and relieves itching. It is used for colds, headaches, toothaches, rheumatic pain, sinusitis, leukorrhea, and sores, carbuncles, and swelling.

[0018] Chuanxiong: Pungent and warm in flavor, it enters the Liver and Gallbladder Meridians. It promotes qi circulation, relieves depression, dispels wind and dampness, and promotes blood circulation and relieves pain. It treats headaches and dizziness due to wind-cold, flank pain and abdominal pain, cold arthritis and muscle spasms, amenorrhea, dystocia, postpartum pain and blood stasis, carbuncles, and ulcers. It is used for menstrual irregularities, amenorrhea, dysmenorrhea, abdominal pain due to lumps, stabbing pain in the chest and flanks, swelling and pain from falls, headaches, and rheumatic pain.

[0019] White mustard seeds: Pungent in flavor, warm in nature, enter the lung meridian. They dispel phlegm and stimulate qi, dissipate stagnation and reduce swelling. They are used for symptoms such as cold phlegm stagnation, chest fullness and flank pain, cough, reverse breathing, and excessive phlegm.

[0020] Turtle Shell: Salty in taste, slightly cold in nature, enters the Liver and Kidney meridians. It nourishes Yin and suppresses Yang, reduces fever and eliminates steaming, softens and disperses lumps, and is used for Yin deficiency fever, bone steaming and fatigue fever, Yin deficiency and Yang hyperactivity, dizziness, internal wind movement, amenorrhea, lumps, chronic malaria, and malarial mother.

[0021] In summary, it can be seen that the Chinese medicine composition of the present invention also has sufficient theoretical support in modern pharmacological research, and the Chinese medicine composition of the present invention can have a good therapeutic and / or preventive effect on adenoids hypertrophy in children.

[0022] The prescription of the Chinese medicine composition of the present invention is explained as follows:

[0023] According to Traditional Chinese Medicine, enlarged adenoids typically manifest as nasal congestion, a nasal sound when speaking, snoring during sleep, and severe apnea caused by breath-holding. This can lead to secretory otitis media, tinnitus, and hearing loss. If left untreated for a long time, it can develop into an adenoid facies. Adenoid hypertrophy is associated with repeated inflammatory stimulation, such as acute and chronic rhinitis, tonsillitis, and influenza, which can cause pathological adenoid hyperplasia. Furthermore, allergic reactions, endocrine disorders, and malnutrition can also contribute to adenoid hypertrophy.

[0024] The main causes of adenoid hypertrophy in children include the following: (1) Exogenous wind-cold: This refers to the human body being affected by the cold weather outside, causing lung qi stagnation and breathing difficulties; (2) Improper diet: For example, overeating raw, cold, or greasy food may lead to abnormal spleen and stomach function, which accumulates into damp heat and invades the head and face, blocking the clear orifices; (3) Spleen and lung qi deficiency: This leads to poor circulation of qi and blood, and deficiency will affect the nine orifices; (4) Phlegm stagnation: This is due to long-term uncontrolled diet, which damages the spleen and stomach, leading to dysfunction of spleen function, accumulation of water and moisture, and phlegm stagnation. Phlegm stagnation condenses on the surface of the adenoids and blocks the airway; (5) Intestinal food accumulation: Traditional Chinese medicine believes that most cases of adenoid hypertrophy in children are caused by intestinal food accumulation. "Children's spleen is often insufficient." The lungs and large intestine are exterior and interior to each other. Problems with large intestine transmission can accumulate in the lungs, resulting in symptoms of lung meridian stagnation and heat. The above-mentioned causes lead to poor circulation of Qi and blood, impaired water metabolism, and stagnation of phlegm, which ultimately lead to the basic pathogenesis of proliferative changes in adenoid tissue.

[0025] It can be seen that the etiology and pathogenesis of adenoids hypertrophy are closely related. The Chinese medicine composition of the present invention comprehensively and dialectically analyzes adenoids hypertrophy, and through the reasonable combination of monarch, minister, assistant and guiding ingredients, takes the treatment principles of dispelling wind and relieving exterior symptoms, resolving phlegm and dispersing nodules, and clearing the nasal passages, thereby achieving the effects of reducing swelling and dispersing nodules, clearing the nose and opening the orifices, and improving nasal permeability.

[0026] The overall therapeutic approach of the present invention for adenoid hypertrophy is mainly to resolve phlegm, open the orifices, activate blood circulation, reduce swelling, dissipate stagnation, and improve breathing. Asarum and white mustard seeds are the main drugs. Asarum warms and clears the nine orifices and resolves phlegm, and assists white mustard seeds in strengthening the effect of resolving phlegm and removing nasal discharge, reducing the surface attachments of the glandular mucosa, and increasing the nasal ventilation channel. Angelica dahurica is the ministerial drug, which is good at treating headaches and is known as the plant musk. Its aromatic power of opening the orifices can lead all drugs directly to the lesions. Turtle shell is the adjuvant drug, which is good at reducing swelling and dissipating stagnation, and can treat all kinds of symptom accumulation. Chuanxiong is the guiding drug, which is a blood-qi drug. It assists Angelica dahurica in relieving pain, activating blood circulation and promoting qi, and has a significant effect of activating blood circulation and reducing swelling, and can quickly relieve the swelling of the glands in the acute stage. The above drugs work synergistically to remove attachments on the surface of the gland, activate blood circulation to eliminate acute inflammation, promote aromatic circulation to open the orifices, and reduce swelling, disperse nodules and rupture the glandular nucleus to achieve the purpose of improving nasal permeability, solving symptoms such as snoring at night, nasal congestion, shortness of breath, apnea, hypoxia and headache.

[0027] Taking into account the pharmacopoeia's requirements for the maximum dosage of asarum and the safety of its use in children, controlling the dosage of asarum within the range of 0.5-1.2 parts by weight can maximize its effect of opening the orifices within the safe range of its use in children; based on the experience of traditional "Sanfu Plaster" proportions, large doses of white mustard seeds can cause skin blistering, so the white mustard seeds are controlled within a safe range of 0.5-1.2 parts by weight; combined with the warming nature of asarum, while warming and transforming cold drinks, it is also necessary to prevent signs of excessive heat and internal heat, and turtle shell has the salty and cold effect of softening hard masses, while reducing swelling and dispersing nodules, it restrains the main medicine and avoids excessive dryness, so the proportion of turtle shell is slightly higher than that of the main medicine. The assistant drug Angelica dahurica has a strong aromatic power to open the orifices and assist the main drug to strengthen the opening of the orifices and stop nosebleeds, but too much fragrance can easily damage Qi; the auxiliary drug Chuanxiong is known as a blood-qi drug. Excessive dosage can prevent bleeding and cause nosebleeds. A small amount can act like a boat to guide the drug up the head and face to the affected area. The reasonable ratio of the above Chinese medicinal materials is obtained by comprehensively controlling the dosage of the entire medicine package and the inventor's many years of experience.

[0028] Furthermore, the Chinese medicine composition is composed of the following Chinese medicinal materials in parts by weight:

[0029]

[0030] Furthermore, the Chinese medicine composition is composed of the following Chinese medicinal materials in parts by weight:

[0031]

[0032]

[0033] Furthermore, the Chinese medicine composition is composed of the following Chinese medicinal materials in parts by weight:

[0034]

[0035] The second aspect of the present invention provides a traditional Chinese medicine preparation, which includes the traditional Chinese medicine composition for reducing swelling, dispersing nodules, and clearing the nose and opening the orifices proposed in the first aspect of the present invention. The traditional Chinese medicine preparation is an external preparation.

[0036] Furthermore, the Chinese medicine preparation is in the form of an ointment or powder. During use, the ointment can be applied directly to the Dazhui and Feishu acupoints, or the powder can be made into a medicine bag and applied to the Dazhui and Feishu acupoints. In actual use, the Chinese medicine dosage form can be flexibly selected based on a comprehensive consideration of the method of administration, the location of administration, and the efficacy.

[0037] The third aspect of the present invention provides a Chinese medicine patch, which comprises a carrier and the Chinese medicine composition for reducing swelling, dispersing nodules, and clearing the nose and opening the orifices proposed in the first aspect of the present invention.

[0038] Furthermore, the Chinese medicine patch also includes rice wine, and the ratio of the rice wine, the Chinese medicine composition and the rice wine is 1:1-2.

[0039] Optionally, the carrier includes non-woven fabric, gauze, adhesive tape, adhesive plaster or medical rubber.

[0040] A fourth aspect of the present invention provides a method for preparing a Chinese medicine patch, which is applied to the Chinese medicine patch provided in the third aspect of the present invention, and the preparation method comprises:

[0041] Weigh each Chinese medicinal material by weight and mix them;

[0042] The mixed Chinese medicinal materials are crushed and passed through a 40-100 mesh sieve, preferably an 80 mesh sieve, to obtain a powdered Chinese medicinal mixture;

[0043] Adding auxiliary materials to the powdered Chinese medicine mixture to prepare a dressing;

[0044] The dressing is placed on a carrier to prepare a patch. In practical applications, the dressing can be prepared into a medicine ball, which is then pressed into a cake shape, and then the cake-shaped dressing is placed on a carrier to obtain a patch.

[0045] An optional method of using the Chinese medicine patch of the present invention is as follows:

[0046] Medication treatment course: Apply for two weeks continuously, one patch a day, two hours each time;

[0047] Dosage: External acupuncture point application, apply to Dazhui point and Feishu point.

[0048] The fifth aspect of the present invention provides a use of the Chinese medicine composition for reducing swelling, dispersing nodules, and clearing the nose and opening the orifices proposed in the first aspect of the present invention, or the Chinese medicine preparation proposed in the second aspect of the present invention, or the Chinese medicine patch proposed in the third aspect of the present invention in the preparation of a medicine, wherein the medicine is used to prevent and / or treat adenoid hypertrophy in children.

[0049] Compared with the prior art, the present invention has the following beneficial effects:

[0050] The present invention provides a traditional Chinese medicine composition consisting of 0.5-1.2 parts by weight of asarum, 0.5-1.2 parts by weight of white mustard seeds, 0.5-1.2 parts by weight of angelica dahurica, 1.5-3.6 parts by weight of scabra occidentalis and 0.5-1.2 parts by weight of ligusticum chuanxiong. The traditional Chinese medicine composition can achieve significant therapeutic effects in treating adenoid hypertrophy in children, and has simple medicinal ingredients, low toxicity and side effects, and is safe and reliable. DETAILED DESCRIPTION

[0051] The present invention is further illustrated below by describing specific implementation methods, but this is not intended to limit the present invention. Those skilled in the art can make various modifications or improvements based on the basic ideas of the present invention, but as long as they do not deviate from the basic ideas of the present invention, they are all within the scope of the present invention.

[0052] Example

[0053] Example 1

[0054] The Chinese medicinal materials asarum, white mustard seeds, angelica dahurica, scabra and Chuanxiong that meet the quality standards are selected and mixed according to the formula of 1 weight part of asarum, 1 weight part of white mustard seeds, 1 weight part of angelica dahurica, 3 weight parts of scabra and 1 weight part of Chuanxiong. The mixed Chinese medicinal materials are crushed by a grinder, and the crushed Chinese medicinal mixture is passed through an 80-mesh sieve to prepare a powder.

[0055] Example 2

[0056] The Chinese medicinal materials asarum, white mustard seeds, angelica dahurica, scabra and Chuanxiong that meet the quality standards are selected and mixed according to the formula of 0.5 weight part of asarum, 0.6 weight part of white mustard seeds, 0.6 weight part of angelica dahurica, 1.5 weight part of scabra and 0.5 weight part of Chuanxiong. The mixed Chinese medicinal materials are crushed by a grinder, and the crushed Chinese medicinal mixture is passed through a 100-mesh sieve to prepare a powder.

[0057] Example 3

[0058] The Chinese medicinal materials asarum, white mustard seeds, angelica dahurica, scabra and Chuanxiong that meet the quality standards are selected and mixed according to the formula of 0.9 weight part of asarum, 1.2 weight parts of white mustard seeds, 0.5 weight part of angelica dahurica, 1.8 weight parts of scabra and 0.9 weight part of Chuanxiong. The mixed Chinese medicinal materials are crushed by a grinder, and the crushed Chinese medicinal mixture is passed through an 80-mesh sieve to prepare a powder.

[0059] Example 4

[0060] The Chinese medicinal materials asarum, white mustard seeds, angelica dahurica, scabra and Chuanxiong that meet the quality standards are selected and mixed according to the formula of 0.8 weight parts of asarum, 0.5 weight parts of white mustard seeds, 0.9 weight parts of angelica dahurica, 2.7 weight parts of scabra and 1.2 weight parts of Chuanxiong. The mixed Chinese medicinal materials are crushed by a grinder, and the crushed Chinese medicinal mixture is passed through an 80-mesh sieve to prepare a powder.

[0061] Example 5

[0062] Select the Chinese medicinal materials Asarum, white mustard seeds, Angelica dahurica, Carapace of Turmeric and Chuanxiong that meet the quality standards, and mix them according to the formula of 1.2 parts by weight of Asarum, 0.9 parts by weight of white mustard seeds, 1.2 parts by weight of Angelica dahurica, 2.4 parts by weight of Carapace of Turmeric and 0.8 parts by weight of Chuanxiong, use a grinder to grind the mixed Chinese medicinal materials, and pass the crushed Chinese medicine mixture through a 100-mesh sieve;

[0063] Take an appropriate amount of vaseline and heat it to melt it into liquid. Take the sieved Chinese medicine powder and add it to the liquid vaseline. Stir it repeatedly to make a paste. Let it stand and solidify into a paste to prepare an ointment.

[0064] Example 6

[0065] Select the Chinese medicinal materials Asarum, white mustard seeds, Angelica dahurica, Aojia and Chuanxiong that meet the quality standards, and mix them according to the formula of 0.6 weight parts of Asarum, 0.8 weight parts of white mustard seeds, 0.7 weight parts of Angelica dahurica, 3.6 weight parts of Aojia, and 0.6 weight parts of Chuanxiong, use a grinder to grind the mixed Chinese medicinal materials, and pass the crushed Chinese medicine mixture through an 80-mesh sieve;

[0066] Take an appropriate amount of vaseline and heat it to melt it into liquid. Take the sieved Chinese medicine powder and add it to the liquid vaseline. Stir it repeatedly to make a paste. Let it stand and solidify into a paste to prepare an ointment.

[0067] Example 7

[0068] Select Chinese medicinal materials that meet the quality standards, such as asarum, white mustard seeds, angelica dahurica, chela ocellariae and Chuanxiong, and use a grinder to grind the mixed Chinese medicinal materials according to 0.7 weight parts of asarum, 0.8 weight parts of white mustard seeds, 0.8 weight parts of angelica dahurica, 3 weight parts of chela ocellariae and 0.7 weight parts of Chuanxiong, and pass the crushed Chinese medicine mixture through a 40-mesh sieve;

[0069] The sieved Chinese medicinal mixture is added with yellow rice wine to prepare a dressing, wherein the ratio of the Chinese medicinal composition to the yellow rice wine is 1:1. The dressing is placed on gauze to prepare a patch.

[0070] Example 8

[0071] Select the Chinese medicinal materials Asarum, white mustard seeds, Angelica dahurica, Carapace of Turmeric and Chuanxiong that meet the quality standards, and mix them according to the formula of 1.1 weight parts of Asarum, 0.7 weight parts of white mustard seeds, 1.1 weight parts of Angelica dahurica, 3.3 weight parts of Carapace of Turmeric and 1.1 weight parts of Chuanxiong, use a grinder to grind the mixed Chinese medicinal materials, and pass the crushed Chinese medicine mixture through a 100-mesh sieve;

[0072] The sieved Chinese medicinal mixture is added with yellow rice wine to prepare a dressing, wherein the ratio of the Chinese medicinal mixture to the yellow rice wine is 1:2. The dressing is placed on an adhesive tape to prepare a patch.

[0073] Test example

[0074] This test example is a clinical study on the Chinese medicine patch of Example 1 in treating adenoids hypertrophy in children.

[0075] Case selection: Sixty children with adenoid hypertrophy were randomly selected from Beijing Huimin Children's Hospital of Traditional Chinese Medicine. The average age of the children was 6 years and 3 months, and the male to female ratio was 1:1.

[0076] 1. Diagnosis is based on:

[0077] (1) Clinical symptoms: Patients with adenoid hypertrophy usually experience nasal congestion, runny nose, ear stuffiness, ear pain, hearing loss, pharyngeal discomfort, and coughing. If the condition is more serious, symptoms such as apnea, snoring during sleep, slurred speech, and loss of appetite may also occur;

[0078] (2) Nasal endoscopy: Adenoid tissue can be seen protruding from the posterior nasal cavity to the anterior nasal cavity. It can be hemispherical or conical in shape with a smooth surface. There is a lot of secretions in the posterior nasal cavity. It is generally difficult to push the adenoids into the nasopharynx.

[0079] (3) Lateral nasopharyngeal radiograph: This is a commonly used imaging method. The degree of hypertrophy is determined by measuring the ratio (A / N) of adenoid thickness (A value) to nasopharyngeal width (N value): normal is 0.5-0.6, 0.61-0.70 is mild hypertrophy, 0.71-0.80 is moderate hypertrophy, and ≥0.80 is severe hypertrophy.

[0080] 2. Symptom classification criteria

[0081] (1) Clinically, adenoids hypertrophy is divided into three levels: mild, moderate, and severe.

[0082] Mild: Snoring is mild and even, with occasional apnea, which has little impact on sleep quality and no obvious daytime sleepiness. Polysomnography (PSG): AHI index (apnea-hypopnea index) 5 ≤ AHI < 15 times / hour

[0083] Moderate: The snoring is louder and there are intermittent apnea. The patient will experience varying degrees of sleepiness during the day. Polysomnography (PSG): AHI index (apnea-hypopnea index) 15 ≤ AHI < 30 times / hour

[0084] Severe: Loud, irregular snoring with frequent apnea. Patients experience daytime sleepiness, fatigue, difficulty concentrating, and even cognitive impairment and personality changes. Polysomnography (PSG): Apnea-hypopnea index (AHI) ≥ 30 events / hour.

[0085] (2) According to the lateral nasopharyngeal radiograph (A / N) standard, adenoid hypertrophy is divided into three levels: mild, moderate, and severe:

[0086] Normal: A / N is 0.5-0.6:

[0087] Mild: A / N is 0.61-0.70;

[0088] Moderate: A / N is 0.71-0.8;

[0089] Severe: A / N≥0.80

[0090] 3. Test process

[0091] (1) According to the clinical snoring symptom classification criteria, 12 children were classified as moderate to severe, 38 children were classified as moderate, and 10 children were classified as mild. According to the lateral nasopharyngeal radiograph (A / N) criteria, 16 children were classified as moderate to severe, 34 children were classified as moderate, and 10 children were classified as mild.

[0092] (2) Medication process: The Chinese medicine patch prepared from the Chinese medicine composition of Example 1 was applied to the Dazhui and Feishu points of all children enrolled in the trial for 2 consecutive weeks, once a day, and each application lasted 2 hours.

[0093] (3) Criteria for judging efficacy: The clinical effect of treatment is judged by comparing the severity of snoring before and after treatment in the same child and the changes in the values of nasopharyngeal lateral radiographs. Finally, the overall effective rate is calculated as the clinical efficacy judgment standard.

[0094] 4. Test results

[0095] (1) Statistical comparison of the data of the experimental children at different symptom levels before and after treatment. Among them: Table 1 is a comparison of the data of the children enrolled according to the clinical snoring symptom classification standard at different symptom levels before and after treatment; Table 2 is a comparison of the data of the children enrolled according to the nasopharyngeal lateral radiograph (A / N) standard at different symptom levels before and after treatment.

[0096] Table 1:

[0097]

[0098] Table 2:

[0099]

[0100]

[0101] From the above results, it can be seen that no matter what symptom classification standard is used, children with different symptom levels can achieve better therapeutic effects after treatment with the patch made from the Chinese medicine composition of this embodiment, with an effective rate of more than 67%. It can be seen that the Chinese medicine composition of this embodiment is effective in treating adenoid hypertrophy in children.

[0102] 5. Case analysis:

[0103] A 3-year-old boy developed runny nose, cough, and sore throat due to an external infection a week ago. Despite treatment, he continued to experience nasal congestion and snoring at night. Nasal endoscopy revealed approximately two-thirds of his adenoids were enlarged. His parents refused the Western medication montelukast and sought treatment with Traditional Chinese Medicine (TCM). His nasal mucosa was congested and swollen to the second degree, his pharynx was red, and there was hyperplasia of the posterior pharyngeal lymphoid follicles. His tongue was red with a thick, greasy coating, and his pulse was slippery. The diagnosis was phlegm-heat stagnation, and the treatment principle was to clear heat and resolve phlegm while also promoting dredgement. He was treated with a Xiaoting Tissue Patch. Upon follow-up one week later, the snoring had largely ceased, and he experienced no daytime nasal discomfort, essentially achieving clinical recovery. He continued the application for another week to consolidate the therapeutic effect.

[0104] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or substitute equivalents for some of the technical features. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for reducing swelling, dispersing stagnation, and clearing the nose and opening the orifices, characterized in that: The Chinese medicine composition is composed of the following Chinese medicinal materials in parts by weight:

2. The Chinese medicine composition for reducing swelling, dispersing stagnation, and clearing the nose and opening the orifices according to claim 1, characterized in that: The Chinese medicine composition is composed of the following Chinese medicinal materials in parts by weight:

3. The Chinese medicine composition for reducing swelling, dispersing stagnation, and clearing the nose and opening the orifices according to claim 1, characterized in that: The Chinese medicine composition is composed of the following Chinese medicinal materials in parts by weight:

4. The Chinese medicine composition for reducing swelling, dispersing stagnation, and clearing the nose and opening the orifices according to claim 1, characterized in that: The Chinese medicine composition is composed of the following Chinese medicinal materials in parts by weight:

5. A Chinese medicine preparation, characterized in that The Chinese medicine preparation comprises the Chinese medicine composition for reducing swelling, dispersing nodules, and clearing the nose and opening the orifices according to any one of claims 1 to 4, and the Chinese medicine preparation is an external preparation.

6. The Chinese medicine preparation according to claim 5, characterized in that The dosage form of the Chinese medicine preparation is ointment or powder.

7. A Chinese medicine patch, characterized in that: The Chinese medicine patch comprises a carrier and the Chinese medicine composition for reducing swelling, dispersing nodules, and clearing the nose and opening the orifices according to any one of claims 1 to 4.

8. The Chinese medicine patch according to claim 7, characterized in that The Chinese medicine patch also includes yellow rice wine, and the ratio of the yellow rice wine, the Chinese medicine composition and the yellow rice wine is 1:1-2.

9. A method for preparing the Chinese medicine patch according to claim 7 or 8, characterized in that: The preparation method comprises: Weigh each Chinese medicinal material by weight and mix them; The mixed Chinese medicinal materials are crushed and passed through a 40-100 mesh sieve to obtain a powdered Chinese medicinal mixture; Adding auxiliary materials to the powdered Chinese medicine mixture to prepare a dressing; The dressing is placed on a carrier to prepare a patch.

10. Use of the Chinese medicine composition for reducing swelling, dispersing nodules, and clearing the nose and opening the orifices according to any one of claims 1 to 4, or the Chinese medicine preparation according to any one of claims 5 or 6, or the Chinese medicine patch according to claim 7 or 8 in preparing medicines, characterized in that: The medicine is used for preventing and / or treating adenoid hypertrophy in children.

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