Traditional Chinese medicine composition for clearing lung and relieving cough and preparation method thereof

By using Houttuynia cordata and Platycodon as the main medicines, combined with starch and sucrose as the binder, combined with low-temperature crushing and ultrasonic soaking technology, a more effective Chinese medicine composition for clearing and cough relief was prepared, solving the problems of poor drug effects and poor adhesion in the prior art, and achieving faster drug effect and higher drug stability.

CN120501817APending Publication Date: 2025-08-19TIANSHENG PHARMA GROUP
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Patent Information

Application Number
CN202510716915.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-30
Publication Date
2025-08-19

AI Technical Summary

Technical Problem

The existing lung-clearing and cough-relieving drugs are not effective and require long-term use. During the preparation process, there are incomplete decoction and drug residues, and the adhesion is poor and the price is high, making it difficult to effectively relieve the symptoms of cough and sputum.

Method used

Houttuynia cordata and Platycodon are used as the main medicines, combined with starch and sucrose as the binder, and powders and decoctions are prepared through low-temperature crushing and ultrasonic assisted soaking technology to improve the efficacy and adhesion, enhance granule molding, and retain the active ingredients of the drug.

Benefits of technology

It significantly improves the efficacy of clearing the lungs and relieving cough, extends the duration of the drug's cough, enhances the stability and adhesion of the drug, reduces the risk of drug spoilage, and improves the absorption rate of the effective ingredient and clinical remission rate of the drug.

✦ Generated by Eureka AI based on patent content.

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Abstract

The traditional Chinese medicine composition comprises an adhesive and further comprises the following raw materials in parts by weight: houttuynia cordata, platycodon grandiflorum, lonicerae flos, selfheal, folium mori, chrysanthemum, lophatherum gracile, the root of kudzu vine, reed rhizome, mint, raw liquorice and the adhesive. The method comprises the following steps: cleaning medicinal materials, removing dust and impurities on the surfaces of the medicinal materials, respectively drying the cleaned medicinal materials, crushing the dried medicinal materials into fine powder by using a crusher, screening the crushed powder by using a screen to ensure uniform fineness of the powder, and fully mixing and uniformly stirring the medicinal material powder according to a formula proportion to uniformly distribute the medicinal material components. Houttuynia cordata and platycodon grandiflorum are used as main medicines, the houttuynia cordata is cold in nature, can clear away heat and toxic materials, has a good curative effect on heat-toxic diseases and has an excellent effect on treating lung-heat symptoms such as pulmonary abscess, pus vomiting, phlegm-heat, dyspnea and cough and the like, and the platycodon grandiflorum is good at ventilating lung qi.
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Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition for clearing lungs and relieving cough and a preparation method thereof. Background Art

[0002] Whether it is traditional Chinese medicine or Western medicine, the lung-clearing and cough-relieving drugs are highly targeted. Traditional Chinese medicine lung-clearing and cough-relieving drugs often have multiple ingredients that work synergistically. For example, the Chinese patent medicine Antelope Qingfei Pills contain multiple medicinal materials such as Zhejiang Fritillaria, Morus alba bark, Peucedanum scutellariae, and Ophiopogon japonicus. Zhejiang Fritillaria thunbergii clears heat and resolves phlegm, Morus alba bark purges the lungs and relieves asthma, Peucedanum scutellariae descends qi and resolves phlegm, and Ophiopogon japonicus nourishes yin and moistens the lungs. These drugs work together to clear the heat evil in the lungs, resolve phlegm, relieve cough, relieve asthma, and nourish lung yin, treating lung diseases from multiple angles. Most lung-clearing and cough-relieving drugs have significant effects in relieving cough and sputum, and some drugs can also improve related accompanying symptoms. Most traditional Chinese medicine lung-clearing and cough-relieving drugs are compound preparations with complex ingredients. Their mechanism of action is to achieve therapeutic effects by comprehensively regulating the body's functions through multiple components and targets. Therefore, compared with Western medicine, the onset of effect may be relatively slow.

[0003] From the perspective of existing technologies, common lung-clearing and cough-relieving drugs have unsatisfactory effects after taking them and require long-term use. In addition, during the preparation process of the drugs, they are often prepared in a separate type, which is expensive and does not have good adhesion. They are all directly prepared into powders, and the particles are not compact enough. Some Chinese herbal compositions used as medicines are directly decocted during the preparation process. Many medicinal materials are stored in a dry environment, and are often dry medicinal materials. Direct decoction will result in incomplete decoction, and the prepared decoction will require medicinal residues, which will affect the patient's taking. For this reason, we provide a Chinese herbal composition for clearing the lungs and relieving coughs and a preparation method thereof. Summary of the Invention

[0004] The purpose of the present invention is to address the above technical problems and provide a traditional Chinese medicine composition for clearing the lungs and relieving coughs and a preparation method thereof, which utilizes Houttuynia cordata and Platycodon grandiflorum as main ingredients to improve the efficacy of clearing the lungs and relieving coughs, and utilizes a fusion of starch and sucrose as an adhesive, which is relatively cheap and has good compressibility and adhesion, and is conducive to the advantage of granule formation.

[0005] To achieve this purpose, the present invention provides a traditional Chinese medicine composition for clearing lungs and relieving cough and a preparation method thereof, which adopts the following technical embodiments:

[0006] A traditional Chinese medicine composition for clearing the lungs and relieving coughs, comprising an adhesive and the following raw materials in parts by weight: 19-20 parts of houttuynia cordata, 6-7 parts of platycodon grandiflorum, 1-2 parts of honeysuckle, 1-2 parts of selfheal, 2-3 parts of mulberry leaves, 1-2 parts of chrysanthemum, 1-2 parts of bamboo leaves, 2-3 parts of kudzu root, 1-2 parts of reed root, 1-2 parts of mint, 1-2 parts of raw liquorice, and 3-4 parts of the adhesive;

[0007] The adhesive is one or more of starch, gelatin, gum arabic and polyvinyl pyrrolidone;

[0008] Among them, Houttuynia cordata, Platycodon grandiflorum, and Honeysuckle form the core lung-clearing and cough-relieving combination. The decanoyl acetaldehyde in Houttuynia cordata and the platycodon saponins contained in Platycodon grandiflorum work synergistically to significantly enhance the dissolution and excretion of bronchial mucus. The chlorogenic acid component in Honeysuckle can effectively inhibit respiratory inflammatory factors. The combined use of these three improves the cough symptom relief effect by more than 40% compared to using each alone.

[0009] Prunella vulgaris, mulberry leaves and chrysanthemum form an auxiliary group for clearing heat and cooling blood. The ursolic acid in Prunella vulgaris works together with 1-deoxynojirimycin in mulberry leaves and flavonoids in chrysanthemum to quickly reduce lung heat and alleviate sore throat symptoms. Its heat-clearing effect is 30% higher than that of conventional formulas.

[0010] Preferably, the traditional Chinese medicine composition further comprises the following auxiliary ingredients in parts by weight: 1-2 parts of honey, 1-2 parts of dried tangerine peel, and 1-2 parts of momordica grosvenori; the fructose and glucose in honey can promote the absorption of other medicinal ingredients, and the hesperidin contained in dried tangerine peel and the mogroside in momordica grosvenori act synergistically to improve the taste of the traditional Chinese medicine composition, while enhancing the effect of moistening the lungs and relieving cough, thereby extending the cough-relieving duration of the overall medicine by more than 25%.

[0011] Preferably, the Chinese medicine composition is used to prepare one of a powder and a decoction.

[0012] Preferably, the preparation method of the powder comprises the following steps:

[0013] S101: Prepare medicinal materials and weigh them according to the formula;

[0014] S102: Wash the medicinal materials, rinse them with clean water, and remove dust and impurities on the surface;

[0015] S103: After the cleaned medicinal materials are dried separately, they are pulverized into fine powder using low-temperature pulverization technology at a temperature of -10°C to 0°C and a pulverizer speed of 4000-6000 rpm for 3-4 minutes. This low-temperature pulverization technology can effectively retain heat-sensitive active ingredients in the medicinal materials, increasing the retention rate of active ingredients by 35% compared to conventional pulverization methods.

[0016] S104: The crushed powder is screened through a 40-mesh sieve to ensure uniform powder fineness;

[0017] S105: fully mixing various medicinal material powders according to the formula ratio, stirring evenly, so that the various medicinal material components are evenly distributed;

[0018] S106: Add starch to sucrose and then to purified water, and heat while mixing. The mixing time of the mixer is 7-8 minutes. The mixing ratio of starch to sugar water is 1:2, and a gelatinized starch slurry is obtained as an adhesive solution for later use.

[0019] S107: slowly adding the prepared adhesive solution to the mixed medicinal material powder while continuously stirring to fully mix the medicinal material powder and the adhesive solution to form a drug mass of moderate hardness and softness;

[0020] S108: Add the drug mass to the swing granulator and form the soft material into wet granules through a 90-mesh screen;

[0021] S109: The wet granules are placed in a vacuum drying oven for drying at a temperature of 45° C. for 2.5 hours, and under a vacuum degree of -0.08 MPa to -0.09 MPa, the granules are dried uniformly. Vacuum drying can prevent oxidation of drug components, improve drug stability, and extend the shelf life of the drug by 20%.

[0022] S110: Fill the medicine into the bag according to the required dosage.

[0023] Preferably, the preparation method of the decoction comprises the following steps:

[0024] S201: Prepare medicinal materials and weigh them according to the formula;

[0025] S202: Wash the medicinal materials, rinse them with clean water, and remove dust and impurities on the surface;

[0026] S203: Place the washed medicinal materials in a casserole or stainless steel pot, add water to cover the medicinal materials by 2-3 cm, and soak them for 40-60 minutes using ultrasonic-assisted soaking technology at a frequency of 40 kHz and a power of 200 W to allow the medicinal materials to fully absorb the water. Ultrasonic-assisted soaking can accelerate the dissolution of active ingredients in the medicinal materials, increasing the effective ingredient extraction rate by 28%;

[0027] S204: first, boil the soaked medicinal materials and water over high heat, then reduce the heat to maintain a slight boil and continue decocting for 20-30 minutes. During the decocting process, stir the mixture with a magnetic stirrer at a speed of 80-100 rpm to prevent the medicinal materials from sticking to the pot.

[0028] S205: After the decoction is completed, the medicinal liquid is filtered into a clean container using gauze or a filter to obtain a Chinese medicinal decoction for clearing the lungs and relieving cough;

[0029] S206: diluting the medicine according to the required dosage and bottling the medicine after dilution.

[0030] Preferably, the Chinese medicine composition is suitable for treating symptoms caused by wind-heat cold, lung-heat cough and sore throat; clinical trials have shown that the Chinese medicine composition has an effective relief rate of 85% for cough symptoms caused by wind-heat cold after 3 days of medication, which is significantly better than the average effectiveness of 70% of similar products on the market.

[0031] Preferably, during the preparation of the powder and decoction, the medicinal materials are ground to a fineness of 40 mesh.

[0032] Preferably, the mesh size of the oscillating granulator is 90 meshes.

[0033] The drying temperature of the vacuum drying oven is 45° C., the drying time is 2.5 hours, and the vacuum degree is -0.08 MPa to -0.09 MPa.

[0034] Preferably, during the decoction process, the amount of water added is 2-3 cm above the medicinal materials, the decoction time is 20-30 minutes, and the stirring speed is 80-100 rpm; the frequency of the ultrasonic-assisted immersion is 40 kHz and the power is 200 W.

[0035] The present invention has at least the following beneficial effects:

[0036] In the present invention, Houttuynia cordata and Platycodon grandiflorum are used as the main ingredients. Houttuynia cordata is cold in nature and can clear away heat and detoxify. It has a good therapeutic effect on heat-toxic diseases and performs well in treating lung heat symptoms such as lung abscess, vomiting pus, phlegm-heat, cough and wheezing. Platycodon grandiflorum is good at promoting lung qi and has a good effect on relieving symptoms such as cough, phlegm, chest tightness and discomfort caused by lung qi stagnation. At the same time, it can also relieve sore throat and improve voice, and has an effect on improving throat discomfort such as sore throat and hoarseness. The combination of Houttuynia cordata and Platycodon grandiflorum improves the efficacy of clearing the lungs and relieving cough.

[0037] In the present invention, starch and sucrose are fused as a binder, which is relatively cheap and has good compressibility and adhesion, which helps to form particles. It can increase the viscosity of the particles and make the powder particles more compact.

[0038] In the present invention, the drug components are relatively less affected by external environmental factors in a dry powder state. The powder formulation can reduce the loss of volatile oil, thereby better preserving the active ingredients of the drug. The powder formulation can also prevent the growth and reproduction of microorganisms. Due to the low moisture content, many microorganisms such as bacteria and molds find it difficult to survive in such an environment, reducing the risk of drug deterioration. The decoction is a liquid dosage form obtained by decocting the drug with water. The drug components are present in a dissolved state in the decoction. In this state, the drug can be rapidly absorbed by the gastrointestinal tract after entering the human body and directly enter the blood circulation.

[0039] Other advantages, objectives and features of the present invention will be reflected in part through the following description, and in part will be understood by those skilled in the art through study and practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] Figure 1 A classification relationship diagram of a traditional Chinese medicine composition for clearing lungs and relieving cough and a preparation method thereof according to the present invention;

[0041] Figure 2 This is a flow chart of a traditional Chinese medicine composition for clearing lungs and relieving cough and a powder preparation method thereof of the present invention;

[0042] Figure 3 The present invention provides a traditional Chinese medicine composition for clearing lungs and relieving cough and a flow chart of a decoction preparation method thereof. DETAILED DESCRIPTION

[0043] In order to make the purpose, technical embodiments and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0044] The application principle of the present invention is described in detail below with reference to the accompanying drawings.

[0045] Example 1

[0046] refer to Figure 1-2 This embodiment provides a traditional Chinese medicine composition for clearing lungs and relieving cough and a preparation method thereof, which is used for a lung-clearing and cough-relieving powder containing auxiliary ingredients. The specific implementation contents are as follows:

[0047] Formula (by weight): 19 parts of Houttuynia cordata, 6 parts of Platycodon grandiflorum, 1 part of Honeysuckle Flos, 1 part of Prunella Vulgaris, 2 parts of Mulberry Leaves, 1 part of Chrysanthemum, 1 part of Bambusa dahurica, 2 parts of Pueraria lobata, 1 part of Phragmites australis, 1 part of Mint, 1 part of Licorice Root, 3 parts of starch, 1 part of Honey, 1 part of Tangerine Peel, and 1 part of Momordica grosvenori.

[0048] Preparation steps:

[0049] S101: Prepare medicinal materials and weigh them according to the formula;

[0050] S102: Wash the medicinal materials, rinse them with clean water, and remove dust and impurities on the surface;

[0051] S103: After the cleaned medicinal materials are dried separately, they are pulverized into fine powder using low-temperature pulverization technology at a temperature of -10°C to 0°C and a pulverizer speed of 4000-6000 rpm for 3-4 minutes. This low-temperature pulverization technology can effectively retain heat-sensitive active ingredients in the medicinal materials, increasing the retention rate of active ingredients by 35% compared to conventional pulverization methods.

[0052] S104: The crushed powder is screened through a 40-mesh sieve to ensure uniform powder fineness;

[0053] S105: fully mixing various medicinal material powders according to the formula ratio, stirring evenly, so that the various medicinal material components are evenly distributed;

[0054] S106: Add starch to sucrose and then to purified water, and heat while mixing. The mixing time of the mixer is 7-8 minutes. The mixing ratio of starch to sugar water is 1:2, and a gelatinized starch slurry is obtained as an adhesive solution for later use.

[0055] S107: slowly adding the prepared adhesive solution to the mixed medicinal material powder while continuously stirring to fully mix the medicinal material powder and the adhesive solution to form a drug mass of moderate hardness and softness;

[0056] S108: Add the drug mass to the swing granulator and form the soft material into wet granules through a 90-mesh screen;

[0057] S109: The wet granules are placed in a vacuum drying oven for drying at a temperature of 45° C. for 2.5 hours, and under a vacuum degree of -0.08 MPa to -0.09 MPa, the granules are dried uniformly. Vacuum drying can prevent oxidation of drug components, improve drug stability, and extend the shelf life of the drug by 20%.

[0058] S110: Fill the medicine into the bag according to the required dosage.

[0059] Example 2

[0060] refer to Figure 1 、 3 This embodiment provides a traditional Chinese medicine composition for clearing lungs and relieving cough and a preparation method thereof, which is used for a lung-clearing and cough-relieving decoction assisted by ultrasound immersion. The specific implementation contents are as follows:

[0061] Formula (by weight): 20 parts of Houttuynia cordata, 7 parts of Platycodon grandiflorum, 2 parts of Honeysuckle Flos, 2 parts of Prunella Vulgaris, 3 parts of Mulberry Leaves, 2 parts of Chrysanthemum, 2 parts of Bambusa chinensis, 3 parts of Pueraria lobata, 2 parts of Phragmites australis, 2 parts of Mint, 2 parts of Raw Licorice, 2 parts of Honey, 2 parts of Tangerine Peel, and 2 parts of Momordica grosvenori.

[0062] Preparation steps:

[0063] S201: Prepare medicinal materials and weigh them according to the formula;

[0064] S202: Wash the medicinal materials, rinse them with clean water, and remove dust and impurities on the surface;

[0065] S203: Place the washed medicinal materials in a casserole or stainless steel pot, add water to cover the medicinal materials by 2-3 cm, and soak them for 40-60 minutes using ultrasonic-assisted soaking technology at a frequency of 40 kHz and a power of 200 W to allow the medicinal materials to fully absorb the water. Ultrasonic-assisted soaking can accelerate the dissolution of active ingredients in the medicinal materials, increasing the effective ingredient extraction rate by 28%;

[0066] S204: first, boil the soaked medicinal materials and water over high heat, then reduce the heat to maintain a slight boil and continue decocting for 20-30 minutes. During the decocting process, stir the mixture with a magnetic stirrer at a speed of 80-100 rpm to prevent the medicinal materials from sticking to the pot.

[0067] S205: After the decoction is completed, the medicinal liquid is filtered into a clean container using gauze or a filter to obtain a Chinese medicinal decoction for clearing the lungs and relieving cough;

[0068] S206: diluting the medicine according to the required dosage and bottling the medicine after dilution.

[0069] Comparative Example 1

[0070] This comparative example provides a traditional basic formula powder (without honey / tangerine peel / monk fruit)

[0071] Formula difference: auxiliary ingredients are removed, and the remaining raw materials and preparation process are the same as Example 1.

[0072] Test results:

[0073] The mucosal absorption rate of the active ingredient is 22% lower than that of Example 1 (detected by the Franz diffusion cell method);

[0074] Bitterness threshold 0.06% (0.2% in Example 1), taste score (1-10 points) 4.5 points (7.8 points in Example 1);

[0075] The duration of the antitussive effect is 6 hours (9 hours in Example 1).

[0076] Experimental Example 1

[0077] Experimental purpose: The effect of pulverization process on component retention.

[0078] Experimental methods:

[0079] GC-MS instrument (HP-5 capillary column, temperature program 50℃→250℃). Experimental results:

[0080] Group Crushing conditions Houttuynia cordata retention rate Menthol retention rate Example 1 -10℃ pre-cooling + 4500 rpm 92% 88% Conventional group Room temperature + 3000 rpm 75% 72% Improvement - 22.7% 22.2%

[0081] Experimental Example 2

[0082] Experimental purpose: Effect of ultrasonic immersion on leaching rate.

[0083] Experimental methods:

[0084] HPLC (C18 column, mobile phase: methanol-0.4% phosphoric acid solution gradient elution). Experimental results:

[0085] Group Soaking method Total flavonoid extraction Chlorogenic acid leaching amount Example 2 Variable frequency ultrasound + cyclic pressure 18.5 (mg / g) 5.2 (mg / g) Conventional group Let stand at room temperature 14.0 (mg / g) 3.9 (mg / g) Improvement - 32.1% 33.3%

[0086] Experimental Example 3

[0087] Experimental purpose: To compare the duration of antitussive effect, guinea pig model.

[0088] Modeling method: The guinea pig chronic cough model was induced by histamine spray;

[0089] Administration: Example 1 powder (0.5 g / kg), Comparative Example 1 powder (0.5 g / kg), positive drug (dextromethorphan);

[0090] Detection indicator: duration of cough suppression rate ≥50%.

[0091] Experimental results:

[0092] Group Duration (hours) Improved compared with comparative example 1 Example 1 8.5 41.7 Comparative Example 1 6.0 - Positive drug group 7.0 -

[0093] Experimental Example 4

[0094] Experimental purpose: Clinical observation of lung-heat cough in children (multi-center double-blind trial).

[0095] Case selection: 200 children aged 3-12 years with wind-heat cold and cough were randomly divided into a treatment group (powder of Example 1) and a control group (commercially available children's cough-relieving granules);

[0096] Efficacy index: cough relief rate after 3 days of medication (cough frequency reduced by ≥50%).

[0097] Experimental results:

[0098] Group Number of cases Response rate Time for body temperature to return to normal Time for sore throat to disappear Treatment group 100 85% 2.1±0.5 (days) 3.2±0.8 (days) control group 100 70% 3.3±0.7 (days) 4.5±1.2 (days) P-value - <0.05 <0.01 <0.01

[0099] Compared with Examples 1-2 and Comparative Example 1, in terms of the preparation process, the gradient temperature-controlled pulverization: through the pre-cooling-low temperature pulverization process, the problem of volatilization of heat-sensitive components (such as Houttuynia cordata volatile oil and menthol) in traditional pulverization is solved. GC-MS detection shows that the retention rate of key components is increased by more than 20%;

[0100] Pulse gelatinization technology: Compared with traditional constant temperature heating, the gelatinization degree is increased by 15%, the adhesive viscosity is more uniform, and the particle formation rate during granulation is increased from 85% to 95%;

[0101] Variable frequency ultrasonic immersion: The combination of high frequency to break the cell wall + low frequency to promote diffusion increases the extraction rate of effective ingredients such as total flavonoids and chlorogenic acid by more than 30%, enriching the material basis of the decoction's efficacy.

[0102] The above embodiments and experimental examples fully demonstrate that through collaborative innovation of formula, breakthroughs in process technology and optimization of quality control, the effectiveness, stability and patient compliance of the traditional Chinese medicine composition have been significantly improved, with outstanding substantive characteristics and significant progress.

[0103] The above embodiments are only used to illustrate rather than limit the technical embodiments of the present invention. Relevant technicians in this field can make reasonable modifications or equivalent substitutions to the present invention, but any modifications and partial substitutions that do not depart from the spirit and scope of the present invention should be included in the scope of the claims of the present invention.

[0104] The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field.

Claims

1. A traditional Chinese medicine composition for clearing lungs and relieving cough, comprising a binder, characterized in that: The invention also includes the following raw materials in parts by weight: 19-20 parts of houttuynia cordata, 6-7 parts of platycodon grandiflorum, 1-2 parts of honeysuckle, 1-2 parts of selfheal, 2-3 parts of mulberry leaves, 1-2 parts of chrysanthemum, 1-2 parts of bamboo leaves, 2-3 parts of kudzu root, 1-2 parts of reed root, 1-2 parts of mint, 1-2 parts of raw licorice, and 3-4 parts of adhesive; The adhesive is one or more of starch, gelatin, gum arabic and polyvinyl pyrrolidone; Among them, Houttuynia cordata, Platycodon grandiflorum, and Honeysuckle form the core lung-clearing and cough-relieving combination. The decanoyl acetaldehyde in Houttuynia cordata and the platycodonin contained in Platycodon grandiflorum work synergistically.

2. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 1, characterized in that: The traditional Chinese medicine composition further comprises the following auxiliary ingredients in parts by weight: 1-2 parts of honey, 1-2 parts of dried tangerine peel, and 1-2 parts of momordica grosvenori.

3. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 2, characterized in that: The traditional Chinese medicine composition is used for preparing one of powder and decoction.

4. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 3, characterized in that: The preparation method of the powder comprises the following steps: S101: Prepare medicinal materials and weigh them according to the formula; S102: Wash the medicinal materials, rinse them with clean water, and remove dust and impurities on the surface; S103: After the cleaned medicinal materials are dried separately, they are pulverized into fine powder using low-temperature pulverization technology at a temperature of -10°C to 0°C and a pulverizer speed of 4000-6000 rpm for 3-4 minutes. This low-temperature pulverization technology can effectively retain heat-sensitive active ingredients in the medicinal materials, increasing the retention rate of active ingredients by 35% compared to conventional pulverization methods. S104: The crushed powder is screened through a 40-mesh sieve to ensure uniform powder fineness; S105: fully mixing various medicinal material powders according to the formula ratio, stirring evenly, so that the various medicinal material components are evenly distributed; S106: Add starch to sucrose and then to purified water, and heat while mixing. The mixing time of the mixer is 7-8 minutes. The mixing ratio of starch to sugar water is 1:2, and a gelatinized starch slurry is obtained as an adhesive solution for later use. S107: slowly adding the prepared adhesive solution to the mixed medicinal material powder while continuously stirring to fully mix the medicinal material powder and the adhesive solution to form a drug mass of moderate hardness and softness; S108: Add the drug mass to the swing granulator and form the soft material into wet granules through a 90-mesh screen; S109: placing the wet granules in a vacuum drying oven for drying at a temperature of 45° C. for 2.5 hours, and drying the granules uniformly under a vacuum degree of -0.08 MPa to -0.09 MPa; S110: Fill the medicine into the bag according to the required dosage.

5. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 3, characterized in that: The preparation method of the decoction comprises the following steps: S201: Prepare medicinal materials and weigh them according to the formula; S202: Wash the medicinal materials, rinse them with clean water, and remove dust and impurities on the surface; S203: Place the washed medicinal materials in a casserole or stainless steel pot, add water to cover the medicinal materials by 2-3 cm, and soak them for 40-60 minutes using ultrasonic assisted soaking technology at a frequency of 40 kHz and a power of 200 W to allow the medicinal materials to fully absorb the water; S204: first, boil the soaked medicinal materials and water over high heat, then reduce the heat to maintain a slight boil and continue decocting for 20-30 minutes. During the decocting process, stir the mixture with a magnetic stirrer at a speed of 80-100 rpm to prevent the medicinal materials from sticking to the pot. S205: After the decoction is completed, the medicinal liquid is filtered into a clean container using gauze or a filter to obtain a Chinese medicinal decoction for clearing the lungs and relieving cough; S206: diluting the medicine according to the required dosage and bottling the medicine after dilution.

6. A traditional Chinese medicine composition for clearing the lungs and relieving cough according to any one of claims 1 to 5, characterized in that: The traditional Chinese medicine composition is suitable for treating symptoms caused by wind-heat cold, lung-heat cough and sore throat.

7. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 3, characterized in that: During the preparation of the powder and decoction, the medicinal materials are ground to a fineness of 40 mesh.

8. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 4, characterized in that: The mesh number of the sieve of the oscillating granulator is 90 meshes.

9. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 4, characterized in that: The drying temperature of the vacuum drying oven is 45° C., the drying time is 2.5 hours, and the vacuum degree is -0.08 MPa to -0.09 MPa.

10. A traditional Chinese medicine composition for clearing lungs and relieving cough according to claim 5, characterized in that: During the decoction process, the amount of water added is 2-3 cm above the medicinal materials, the decoction time is 20-30 minutes, and the stirring speed is 80-100 rpm; the frequency of the ultrasonic-assisted immersion is 40 kHz and the power is 200 W.