Preparation method and application of microcapsule oil bead essence

Abstract

The invention relates to the technical field of cosmetic preparation, and discloses a preparation method and application of micro-capsule oil bead essence, and the preparation method of the micro-capsule oil bead essence comprises the following steps: S1, wall material preparation: taking 10-16 parts of sodium alginate, 10-14 parts of gelatin and 20-28 parts of polylactic acid-glycolic acid copolymer; s2, preparing a wall material solution; s3, preparing a core material; s4, preparation of core material emulsion: slowly adding the core material into deionized water containing an emulsifier while stirring; s6, curing and forming; and S7, post-treatment: carrying out separation and collection on the cured microcapsules in manners of centrifugation, filtration and the like. The micro-capsule oil bead essence is reasonable in design, and the micro-capsule oil bead essence can deeply moisturize. Hyaluronic acid can absorb a large amount of moisture, so that the skin is moisturized for a long time; ceramide can repair skin barrier and reduce water loss; the glycerin solution is used as a moisturizer, so that the moisturizing effect is further enhanced, and the skin is kept in a tender state all the time.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetic preparation, and in particular to a preparation method and application of microcapsule oil bead essence. Background Art

[0002] As people's demands for skin care continue to rise, skincare products with highly effective moisturizing, repairing, and nourishing properties are gaining widespread attention. Traditional serums have several drawbacks during storage and use, such as the susceptibility of active ingredients to oxidation and volatilization, resulting in poor stability and reduced efficacy. Furthermore, their limited penetration into the skin prevents the active ingredients from reaching deep layers of the skin to exert their effects. Therefore, we propose a method for preparing and applying a microencapsulated oil bead serum to address this issue. Summary of the Invention

[0003] The purpose of the present invention is to solve the shortcomings of the above-mentioned background technology and to propose a preparation method and application of microcapsule oil bead essence.

[0004] In order to achieve the above object, the present invention adopts the following technical solutions:

[0005] A method for preparing microcapsule oil bead essence comprises the following steps:

[0006] S1. Preparation of wall material: 10-16 parts of sodium alginate, 10-14 parts of gelatin, and 20-28 parts of polylactic acid-glycolic acid copolymer are mixed to prepare wall material;

[0007] S2. Preparation of wall material solution: dissolve the wall material in deionized water according to a certain proportion, heat to 50-60°C, and stir for 30-40 minutes to completely dissolve the wall material and form a uniform wall material solution;

[0008] S3. Preparation of core material: 2-10 parts hyaluronic acid, 1-5 parts ceramide, 1-4 parts vitamin E, and 5-15 parts plant essential oil are mixed to prepare the core material. Hyaluronic acid provides deep moisturizing, ceramide can repair the skin barrier, vitamin E has antioxidant effects, and the plant essential oil gives the product a unique fragrance and soothing effect.

[0009] S4. Preparation of core material emulsion: slowly adding the core material into deionized water containing an emulsifier under stirring to obtain a uniform core material emulsion;

[0010] S5, microencapsulation treatment: slowly adding the core material emulsion dropwise to the wall material solution while stirring with a high-speed stirrer at a speed of 1000-1500 rpm to allow the core material emulsion to be encapsulated by the wall material solution to form microcapsules;

[0011] S6. Solidification and molding: slowly add the suspension containing microcapsules into the calcium chloride solution and soak for 30-40 minutes to solidify the microcapsules;

[0012] S7. Post-treatment: The solidified microcapsules are separated and collected by centrifugation, filtration, etc., washed with deionized water to remove residual impurities and unreacted substances, and then dispersed in an appropriate amount of moisturizer to obtain microcapsule oil bead essence.

[0013] Preferably, in S2, an appropriate amount of surfactant is added during the stirring process to reduce the surface tension of the wall material solution, which is beneficial to the subsequent formation of microcapsules.

[0014] Preferably, in S4, the stirring speed is controlled to be 800-1200 rpm, the temperature is maintained at 40-50° C., and the emulsification is carried out for 20-30 minutes.

[0015] Preferably, in S5, the core material emulsion droplet acceleration is controlled at 1-2 ml / min, and the stirring time is continued for 60-90 minutes to ensure that the microcapsules are formed completely and evenly.

[0016] Preferably, the moisturizing agent in S7 is a glycerol solution.

[0017] Preferably, in S1, before mixing, the sodium alginate powder is sieved through an 80-100 mesh sieve to remove impurities and lumps.

[0018] Preferably, in S3, before adding the plant essential oil, the plant essential oil is mixed with an emulsifier, and emulsified under high-speed stirring conditions to form an emulsion, which is then added to the other core material components.

[0019] Preferably, in S5, an ultrasonic device is turned on during the dropwise addition process to assist in dispersion, the ultrasonic power is controlled at 100-200 W, the ultrasonic time does not exceed 5 seconds each time, and ultrasonication is performed every 2-3 minutes.

[0020] Preferably, in S7, the centrifugal speed is set to 3000-5000 rpm, and the centrifugal time is 5-10 minutes.

[0021] The present invention also provides an application of the microcapsule oil bead essence prepared by the above preparation method, characterized in that it is applied to skin care products with moisturizing, repairing and anti-aging effects.

[0022] Compared with the prior art, the present invention provides a preparation method and application of microcapsule oil bead essence, which has the following beneficial effects:

[0023] (1) The microcapsule oil bead essence of the present invention can deeply moisturize the skin. Hyaluronic acid can absorb a large amount of water, making the skin lastingly hydrated; ceramide repairs the skin barrier and reduces water loss; glycerin solution acts as a moisturizer to further enhance the moisturizing effect, keeping the skin moisturized at all times;

[0024] (2) The microcapsule oil bead essence of the present invention has excellent skin repair function. Ceramide helps repair damaged skin barriers and enhance skin resistance; the active ingredients in plant essential oils can promote cell regeneration, accelerate skin self-repair, effectively improve skin sensitivity, redness and swelling, and restore skin to health;

[0025] (3) The microcapsule oil bead essence has a significant anti-aging effect. Vitamin E is an antioxidant, scavenges free radicals, and delays skin aging; peptide ingredients stimulate collagen synthesis, increase skin elasticity, reduce wrinkles, and keep the skin firm and smooth, showing a youthful appearance;

[0026] (4) The plant essential oils added to the product not only give it a unique fragrance, but also have a soothing effect. During use, it can relax the user's body and mind, relieve stress, and provide gentle care for the skin, enhancing the skin care experience and allowing the skin to be cared for in a pleasant atmosphere. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 The present invention provides a flow chart of a method for preparing microcapsule oil bead essence. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0029] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "top", "bottom", "inside", "outside", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as limiting the present invention.

[0030] Example 1

[0031] Reference Figure 1 A method for preparing microcapsule oil bead essence comprises the following steps:

[0032] S1. Preparation of wall material: 16 parts of sodium alginate, 14 parts of gelatin, and 28 parts of polylactic acid-co-glycolic acid copolymer are mixed to prepare wall material;

[0033] S2. Preparation of wall material solution: dissolve the wall material in deionized water according to a certain proportion, heat to 60°C, and stir for 40 minutes to completely dissolve the wall material and form a uniform wall material solution;

[0034] S3. Preparation of core material: 2 parts hyaluronic acid, 1 part ceramide, 1 part vitamin E, and 5 parts plant essential oil are mixed to prepare the core material. Hyaluronic acid provides deep moisturizing, ceramide can repair the skin barrier, vitamin E has antioxidant effects, and the plant essential oil gives the product a unique fragrance and soothing effect.

[0035] S4. Preparation of core material emulsion: slowly adding the core material into deionized water containing an emulsifier under stirring to obtain a uniform core material emulsion;

[0036] S5, microencapsulation treatment: slowly adding the core material emulsion dropwise to the wall material solution while stirring at a speed of 1500 rpm using a high-speed stirrer to allow the core material emulsion to be encapsulated by the wall material solution to form microcapsules;

[0037] S6, solidification and molding: slowly adding the suspension containing microcapsules into the calcium chloride solution and soaking for 40 minutes to solidify the microcapsules;

[0038] S7. Post-treatment: The solidified microcapsules are separated and collected by centrifugation, filtration, etc., washed with deionized water to remove residual impurities and unreacted substances, and then dispersed in an appropriate amount of moisturizer to obtain microcapsule oil bead essence.

[0039] In this embodiment, in S2, an appropriate amount of surfactant is added during the stirring process to reduce the surface tension of the wall material solution, which is beneficial to the subsequent formation of microcapsules.

[0040] In this embodiment, in S4, the stirring speed is controlled to 1200 rpm, the temperature is maintained at 50° C., and the emulsification is carried out for 30 minutes.

[0041] In this embodiment, in S5, the core material emulsion droplet acceleration is controlled at 1 ml / min, and the stirring time is continued for 90 minutes to ensure that the microcapsules are formed completely and uniformly.

[0042] In this embodiment, the moisturizing agent in S7 is a glycerin solution.

[0043] In this embodiment, in S1, before mixing, the sodium alginate powder is sieved through a 100-mesh sieve to remove impurities and lumps.

[0044] In this embodiment, in S3, before adding the plant essential oil, the plant essential oil is mixed with an emulsifier, and emulsified under high-speed stirring conditions to form an emulsion, which is then added to the other core material components.

[0045] In this embodiment, in S5, an ultrasonic device is turned on during the dropwise addition process to assist in dispersion, the ultrasonic power is controlled at 200 W, the ultrasonic time does not exceed 5 seconds each time, and ultrasonication is performed every 3 minutes.

[0046] In this embodiment, in S7, the centrifugal speed is set to 5000 rpm and the centrifugal time is 10 minutes.

[0047] The present invention also provides an application of the microcapsule oil bead essence prepared by the above preparation method, characterized in that it is applied to skin care products with moisturizing, repairing and anti-aging effects.

[0048] Hyaluronic acid is a polysaccharide naturally present in the skin. It has unique moisturizing properties and can absorb and lock in large amounts of water. Its molecular structure contains a large number of hydrophilic groups, which can form hydrogen bonds with water molecules, thereby tightly adsorbing the water molecules around them. In the microcapsule oil bead essence, hyaluronic acid provides a long-lasting moisturizing effect to the skin in this way. Hyaluronic acid of different molecular weights plays different roles in moisturizing. Low molecular weight hyaluronic acid can penetrate deep into the epidermis of the skin, quickly replenishing moisture to the skin, making the skin instantly hydrated. High molecular weight hyaluronic acid mainly forms a moisturizing film on the surface of the skin to prevent moisture from being lost from the surface of the skin, playing a role in long-lasting moisturizing.

[0049] Ceramide is an important component of the skin barrier, which can enhance the skin's ability to retain water. In microcapsule oil bead essence, ceramide can fill the space between skin keratinocytes, making the skin's stratum corneum more tightly arranged and reducing water evaporation. When the skin is stimulated by the external environment, such as dryness, ultraviolet radiation, etc., ceramide can help maintain the skin's dynamic balance and keep the skin's moisture content stable. It can promote the hydration of skin keratinocytes, making it difficult for water in skin cells to be lost, thereby keeping the skin hydrated.

[0050] Ceramide plays an important role in repairing the skin barrier. When the skin is damaged, such as by inflammation, allergies, or sunburn, the synthesis of ceramide will be affected, resulting in impaired skin barrier function. In this case, by using microcapsule oil bead essence containing ceramide, the missing ceramide in the skin can be replenished to help repair the damaged skin barrier. Ceramide can promote the differentiation and proliferation of skin keratinocytes, allowing damaged skin tissue to gradually return to normal. At the same time, it can also reduce the release of inflammatory factors, relieve the skin's inflammatory response, and create a good environment for skin repair.

[0051] Vitamin E is an important antioxidant that can protect unsaturated fatty acids in cell membranes from oxidation and prevent the formation of lipofuscin, a substance that causes skin spots and wrinkles. By inhibiting the formation of lipofuscin, vitamin E can delay the aging process of the skin.

[0052] Example 2

[0053] Reference Figure 1 A method for preparing microcapsule oil bead essence comprises the following steps:

[0054] S1. Preparation of wall material: 13 parts of sodium alginate, 12 parts of gelatin, and 24 parts of polylactic acid-co-glycolic acid copolymer are mixed to prepare wall material;

[0055] S2. Preparation of wall material solution: dissolve the wall material in deionized water according to a certain proportion, heat to 60°C, and stir for 40 minutes to completely dissolve the wall material and form a uniform wall material solution;

[0056] S3. Preparation of core material: 6 parts hyaluronic acid, 3 parts ceramide, 2 parts vitamin E, and 10 parts plant essential oil are mixed to prepare the core material. Hyaluronic acid provides deep moisturizing, ceramide can repair the skin barrier, vitamin E has antioxidant effects, and the plant essential oil gives the product a unique fragrance and soothing effect.

[0057] S4. Preparation of core material emulsion: slowly adding the core material into deionized water containing an emulsifier under stirring to obtain a uniform core material emulsion;

[0058] S5, microencapsulation treatment: slowly adding the core material emulsion dropwise to the wall material solution while stirring at a speed of 1500 rpm using a high-speed stirrer to allow the core material emulsion to be wrapped by the wall material solution to form microcapsules;

[0059] S6, solidification and molding: slowly adding the suspension containing microcapsules into the calcium chloride solution and soaking for 40 minutes to solidify the microcapsules;

[0060] S7. Post-treatment: The solidified microcapsules are separated and collected by centrifugation, filtration, etc., washed with deionized water to remove residual impurities and unreacted substances, and then dispersed in an appropriate amount of moisturizer to obtain microcapsule oil bead essence.

[0061] In this embodiment, in S2, an appropriate amount of surfactant is added during the stirring process to reduce the surface tension of the wall material solution, which is beneficial to the subsequent formation of microcapsules.

[0062] In this embodiment, in S4, the stirring speed is controlled to 1200 rpm, the temperature is maintained at 50° C., and the emulsification is carried out for 30 minutes.

[0063] In this embodiment, in S5, the core material emulsion droplet acceleration is controlled at 1 ml / min, and the stirring time is continued for 90 minutes to ensure that the microcapsules are formed completely and uniformly.

[0064] In this embodiment, the moisturizing agent in S7 is a glycerin solution.

[0065] In this embodiment, in S1, before mixing, the sodium alginate powder is sieved through a 100-mesh sieve to remove impurities and lumps.

[0066] In this embodiment, in S3, before adding the plant essential oil, the plant essential oil is mixed with an emulsifier, and emulsified under high-speed stirring conditions to form an emulsion, which is then added to the other core material components.

[0067] In this embodiment, in S5, an ultrasonic device is turned on during the dropwise addition process to assist in dispersion, the ultrasonic power is controlled at 200 W, the ultrasonic time does not exceed 5 seconds each time, and ultrasonication is performed every 3 minutes.

[0068] In this embodiment, in S7, the centrifugal speed is set to 5000 rpm and the centrifugal time is 10 minutes.

[0069] Example 3

[0070] Reference Figure 1 A method for preparing microcapsule oil bead essence comprises the following steps:

[0071] S1. Preparation of wall material: 106 parts of sodium alginate, 10 parts of gelatin, and 20 parts of polylactic acid-co-glycolic acid copolymer are mixed to prepare wall material;

[0072] S2. Preparation of wall material solution: dissolve the wall material in deionized water according to a certain proportion, heat to 60°C, and stir for 40 minutes to completely dissolve the wall material and form a uniform wall material solution;

[0073] S3. Preparation of core material: 10 parts hyaluronic acid, 5 parts ceramide, 4 parts vitamin E, and 15 parts plant essential oil are mixed to prepare the core material. Hyaluronic acid provides deep moisturizing, ceramide can repair the skin barrier, vitamin E has antioxidant effects, and the plant essential oil gives the product a unique fragrance and soothing effect.

[0074] S4. Preparation of core material emulsion: slowly adding the core material into deionized water containing an emulsifier under stirring to obtain a uniform core material emulsion;

[0075] S5, microencapsulation treatment: slowly adding the core material emulsion dropwise to the wall material solution while stirring at a speed of 1500 rpm using a high-speed stirrer to allow the core material emulsion to be encapsulated by the wall material solution to form microcapsules;

[0076] S6, solidification and molding: slowly adding the suspension containing microcapsules into the calcium chloride solution and soaking for 40 minutes to solidify the microcapsules;

[0077] S7. Post-treatment: The solidified microcapsules are separated and collected by centrifugation, filtration, etc., washed with deionized water to remove residual impurities and unreacted substances, and then dispersed in an appropriate amount of moisturizer to obtain microcapsule oil bead essence.

[0078] In this embodiment, in S2, an appropriate amount of surfactant is added during the stirring process to reduce the surface tension of the wall material solution, which is beneficial to the subsequent formation of microcapsules.

[0079] In this embodiment, in S4, the stirring speed is controlled to 1200 rpm, the temperature is maintained at 50° C., and the emulsification is carried out for 30 minutes.

[0080] In this embodiment, in S5, the core material emulsion droplet acceleration is controlled at 1 ml / min, and the stirring time is continued for 90 minutes to ensure that the microcapsules are formed completely and evenly. In S7, the moisturizer is a glycerol solution. In S1, before mixing, the sodium alginate powder is sieved through a 100-mesh sieve to remove impurities and lumps.

[0081] In this embodiment, in S3, before adding the plant essential oil, the plant essential oil is mixed with an emulsifier, and emulsified under high-speed stirring conditions to form an emulsion, which is then added to the other core material components.

[0082] In this embodiment, in S5, an ultrasonic device is turned on during the dropwise addition process to assist in dispersion, the ultrasonic power is controlled at 200 W, the ultrasonic time does not exceed 5 seconds each time, and ultrasonication is performed every 3 minutes.

[0083] In this embodiment, in S7, the centrifugal speed is set to 5000 rpm and the centrifugal time is 10 minutes.

[0084] The following table shows the performance comparison analysis of the above embodiments:

[0085]

[0086] Table 1

[0087] Preferably, the second embodiment has a balanced wall material ratio (PLGA 24 parts) to provide the best encapsulation efficiency (94.5%) while avoiding excessively large particle size due to high wall material ratio (the first embodiment) or leakage due to low wall material ratio (the third embodiment).

[0088] The standard parts used in the present invention can all be purchased from the market, and special-shaped parts can be customized according to the description in the specification and the drawings. The specific connection methods of each part adopt conventional means such as mature bolts, rivets, welding, etc. in the existing technology. The machinery, parts and equipment all adopt conventional models in the existing technology, and the circuit connection adopts the conventional connection method in the existing technology, which will not be described in detail here.

Claims

1. A method for preparing microcapsule oil bead essence, characterized in that: The steps include: S1. Preparation of wall material: 10-16 parts of sodium alginate, 10-14 parts of gelatin, and 20-28 parts of polylactic acid-glycolic acid copolymer are mixed to prepare wall material; S2. Preparation of wall material solution: dissolve the wall material in deionized water according to a certain proportion, heat to 50-60°C, and stir for 30-40 minutes to completely dissolve the wall material and form a uniform wall material solution; S3, core material preparation: take 2-10 parts of hyaluronic acid, 1-5 parts of ceramide, 1-4 parts of vitamin E, and 5-15 parts of plant essential oil, and mix them to prepare the core material; S4. Preparation of core material emulsion: slowly adding the core material into deionized water containing an emulsifier under stirring to obtain a uniform core material emulsion; S5, microencapsulation treatment: slowly adding the core material emulsion dropwise to the wall material solution while stirring with a high-speed stirrer at a speed of 1000-1500 rpm to allow the core material emulsion to be encapsulated by the wall material solution to form microcapsules; S6. Solidification and molding: slowly add the suspension containing microcapsules into the calcium chloride solution and soak for 30-40 minutes to solidify the microcapsules; S7. Post-processing: The solidified microcapsules are separated and collected by centrifugation, filtration, etc., washed with deionized water to remove residual impurities and unreacted substances, and then dispersed in an appropriate amount of moisturizer to obtain microcapsule oil droplet essence.

2. The method for preparing microcapsule oil droplet essence according to claim 1, characterized in that: In the S2, an appropriate amount of surfactant is added during the stirring process to reduce the surface tension of the wall material solution, which is beneficial to the subsequent formation of microcapsules.

3. The method for preparing microcapsule oil droplet essence according to claim 2, characterized in that: In the step S4, the stirring speed is controlled to be 800-1200 rpm, the temperature is maintained at 40-50° C., and the emulsification is carried out for 20-30 minutes.

4. The method for preparing microcapsule oil droplet essence according to claim 3, characterized in that: In the above-mentioned S5, the core material emulsion droplet addition speed is controlled at 1-2 ml / min, and the stirring time is continued for 60-90 minutes to ensure that the microcapsules are formed completely and uniformly.

5. The method for preparing microcapsule oil droplet essence according to claim 4, characterized in that: In the S7, the moisturizing agent is a glycerol solution.

6. The method for preparing microcapsule oil droplet essence according to claim 5, characterized in that: In S1, before mixing, the sodium alginate powder is sieved through an 80-100 mesh sieve to remove impurities and lumps.

7. The method for preparing microcapsule oil bead essence according to claim 6, characterized in that: In S3, before adding the plant essential oil, the plant essential oil is mixed with an emulsifier, and emulsified under high-speed stirring conditions to form an emulsion, which is then added to the other core material components.

8. The method for preparing microcapsule oil bead essence according to claim 7, characterized in that: In the S5, an ultrasonic device is turned on during the dropwise addition process to assist in dispersion, the ultrasonic power is controlled at 100-200 W, the ultrasonic time does not exceed 5 seconds each time, and the ultrasonication is performed every 2-3 minutes. In the S7, the centrifugal speed is set to 3000-5000 rpm, and the centrifugal time is 5-10 minutes.

9. An application of the microcapsule oil droplet essence prepared by the preparation method according to any one of claims 1 to 8, characterized in that: Used in skin care products with moisturizing, repairing and anti-aging effects.

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