Breathable indwelling needle patch based on polyurethane glue and preparation method of breathable indwelling needle patch

Abstract

The invention provides a breathable remaining needle sticker based on polyurethane glue and a preparation method thereof, and belongs to the technical field of remaining needle stickers, the breathable remaining needle sticker based on polyurethane glue comprises a polyurethane film, a polyurethane glue layer coating one side of the polyurethane film, and release paper covering the polyurethane glue layer; the thickness of the polyurethane film is 10-35 microns, the gram weight of the polyurethane glue layer is 20-50 gsm, the gram weight of the release paper is 50-130 gsm, and the surface, in contact with the polyurethane glue layer, of the release paper is subjected to corona treatment. The preparation method of the breathable indwelling needle patch comprises the steps S1-S4. Polyurethane glue is adopted to replace acrylate glue, so that the air permeability, moisture permeability and biocompatibility of the product are improved; the surface of the release paper is treated through corona, the adhesive property of glue is optimized, the production process is simplified, efficient and low-consumption preparation of the remaining needle patch is achieved, and meanwhile the use safety and comfort of the product are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of indwelling needle patches, and in particular to a breathable indwelling needle patch based on polyurethane glue and a preparation method thereof. Background Art

[0002] Defects of existing technology: Traditional indwelling needle patches mostly use polyurethane film coated with solvent-based acrylic pressure-sensitive adhesive, which has problems such as poor air permeability, poor skin comfort, and easy to cause allergic reactions; in the production of polyurethane glue indwelling needle patches, the traditional release paper process is difficult to meet the adhesion requirements of polyurethane glue, and non-silicone release paper has problems such as unadjustable release force, double-sided release easily leading to silicone oil transfer, and complicated production process, resulting in low production efficiency and high scrap rate.

[0003] To this end, a breathable indwelling needle patch based on polyurethane glue and a preparation method thereof are proposed. Summary of the Invention

[0004] The present invention aims to solve the problems raised in the background technology and provides a breathable indwelling needle patch based on polyurethane glue and a preparation method thereof. Polyurethane glue is used instead of acrylic glue to improve the air permeability and moisture permeability and biocompatibility of the product; by corona treating the surface of the release paper, the glue adhesion performance is optimized, the production process is simplified, and efficient and low-consumption indwelling needle patch preparation is achieved, while improving the safety and comfort of product use.

[0005] The specific technical solutions are as follows:

[0006] A breathable indwelling needle patch based on polyurethane glue, comprising: a polyurethane film, a polyurethane glue layer coated on one side of the polyurethane film, and a release paper covering the polyurethane glue layer; the polyurethane film has a thickness of 10-35 microns, the polyurethane glue layer has a grammage of 20-50 gsm, the release paper has a grammage of 50-130 gsm, and the surface of the release paper in contact with the polyurethane glue layer has been corona treated.

[0007] The polyurethane material itself has high breathability. When combined with a film and glue layer of a specific grammage, it can improve the air and moisture permeability of the indwelling needle patch and reduce the feeling of stuffiness on the skin. After the release paper is corona treated, the surface energy is enhanced, which improves the adhesion stability between the polyurethane glue layer and the release paper, avoiding the problem of film shedding during production. At the same time, it is easy to tear off the release paper during use, and no glue residue will remain on the indwelling needle tube.

[0008] In the aforementioned breathable indwelling needle patch, the polyurethane film is produced by coating a polyurethane solution onto a release paper liner and drying it. The release paper has a grammage of 50-130 gsm. This production method allows the polyurethane film to have a uniform thickness of 10-35 microns. The film is soft and comfortable against the skin, and its structural density and breathability are balanced, protecting the puncture site while allowing the skin to breathe.

[0009] The aforementioned breathable IV patch also includes a side strip attached to one end of the polyurethane film to assist in securing and removing the IV, and a tear tab integrated into the corner of the release paper to assist in removing the release paper from the polyurethane adhesive layer. The side strip helps secure the IV and prevents displacement. When removing the IV patch, the side strip provides a point of force, making the removal process smoother, reducing strain on the skin and pain, while also preventing adhesive residue from breaking during removal.

[0010] In the aforementioned breathable indwelling needle patch, the polyurethane adhesive layer is formed by coating and drying a mixture of polyurethane glue and curing agent in a mass ratio of 100:15-100:35. This ratio allows the adhesive to form a highly flexible adhesive layer upon curing, allowing it to stretch with skin movement and resist cracking. Furthermore, the curing reaction is sufficient, resulting in a strong cohesive layer, ensuring a secure fit and allowing the patch to fall off completely upon removal, reducing allergic reactions.

[0011] The present invention also provides a method for preparing a breathable indwelling needle patch, comprising the following steps:

[0012] S1: Preparing a polyurethane film: coating a polyurethane solution onto a release paper having a grammage of 50-130 gsm, and drying the resulting polyurethane film to form a polyurethane film having a thickness of 10-35 μm;

[0013] S2: Preparation of release paper for coating: Corona treatment of the silicone oil surface of release paper with a gram weight of 50-130gsm, with a corona power of 0.5-6kw;

[0014] S3: Applying polyurethane glue: Mixing polyurethane glue and curing agent in a mass ratio of 100:15-100:35 to prepare a mixed solution, applying the mixed solution to the release paper prepared in S2, and drying to form a glue-coated semi-finished product;

[0015] S4: pasting edge strips and die-cutting: pasting the edge strips on the polyurethane film of the semi-finished glue-coated product obtained in S3, and die-cutting into shape.

[0016] Each step works together to achieve integrated production from material preparation to finished product. Compared with the existing technology that requires two-step production, this simplifies the process and improves production efficiency. Through standardized step control, the scrap rate in the production process can be reduced and product quality consistency can be ensured.

[0017] In the above-mentioned method for preparing a breathable indwelling needle patch, the drying temperature in S1 is 60-120°C and the drying time is 5-20 minutes. This temperature and time range allows the solvent in the polyurethane solution to fully evaporate, while avoiding film aging caused by excessively high temperatures or solvent residue caused by excessively low temperatures, ensuring that the physical properties of the film are stable, such as tensile strength and elongation at break, meet medical requirements.

[0018] In the above-mentioned method for preparing a breathable indwelling needle patch, the drying temperature in S3 is 80-150°C and the drying time is 10-30 minutes. This ensures that the polyurethane glue and the curing agent are fully crosslinked and cured to form a dense adhesive film, thereby improving the cohesive strength and weather resistance of the adhesive layer and avoiding problems such as stickiness or insufficient adhesion caused by incomplete curing.

[0019] In the aforementioned method for preparing a breathable indwelling needle patch, the corona treatment of the release paper in S2 utilizes a high-frequency corona device, achieving a surface tension of 38-50 mN / m. This precise control of the release paper's surface tension optimizes its interfacial compatibility with the polyurethane adhesive. While maintaining the release paper's proper release function, it significantly enhances the adhesive layer's adhesion, resolving the problem of weak bonding between conventional release paper and polyurethane adhesive.

[0020] In the aforementioned method for preparing a breathable indwelling needle patch, the polyurethane glue in S3 has a solids content of 100%, and the curing agent is an isocyanate curing agent. The appropriate solids content ensures moderate fluidity during glue application, facilitating uniform film formation. The isocyanate curing agent reacts efficiently with the polyurethane glue, allowing for rapid curing and shortening production cycles. Furthermore, the cured adhesive layer exhibits excellent water resistance and biocompatibility, reducing the risk of skin allergies.

[0021] In the aforementioned method for preparing a breathable indwelling needle patch, the edge strips in S4 are made of medical non-woven fabric or polyurethane film, and have a width of 5-20 mm. Medical non-woven fabric or polyurethane film is soft, has good skin compatibility, and is less likely to cause irritation. The appropriate width provides sufficient surface area for tearing without excessively increasing the overall thickness of the patch, ensuring comfort and ease of use.

[0022] The present invention has the following beneficial effects:

[0023] 1. Product Performance Optimization: By combining a polyurethane material system with corona-treated release paper, the air and moisture permeability of the indwelling needle patch is significantly improved, solving the skin stuffiness and allergy issues caused by existing acrylic adhesive patches. The flexible design of the adhesive layer and film ensures that the patch is comfortable when applied to the skin and painless and leaves no adhesive residue when removed, improving the patient experience.

[0024] 2. Improved production process: The corona treatment process solves the adhesion problem between polyurethane glue and release paper, avoiding the problems of unadjustable release force and complex production process of traditional non-silicone release paper, achieving one-time molding production, improving production efficiency, and reducing scrap rate and production costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 A schematic structural diagram of a breathable indwelling needle patch based on polyurethane glue provided in an embodiment of the present invention;

[0026] Figure 2 A schematic structural diagram of a breathable polyurethane glue-based indwelling needle patch from another perspective provided by an embodiment of the present invention;

[0027] Figure 3 A schematic diagram of the exploded structure of a polyurethane glue-based breathable indwelling needle patch provided in an embodiment of the present invention;

[0028] Figure 4 Flowchart of the preparation method of the breathable indwelling needle patch based on polyurethane glue provided in an embodiment of the present invention.

[0029] In the attached figure:

[0030] 1. Polyurethane film; 101. Edge strip;

[0031] 2. Polyurethane glue layer;

[0032] 3. Release paper; 301, tear sheet. DETAILED DESCRIPTION

[0033] The technical solution of the present invention will be further described below with reference to the accompanying drawings and through specific implementation methods.

[0034] Among them, the drawings are only used for illustrative purposes and represent only schematic diagrams rather than actual pictures, and should not be understood as limiting this patent; in order to better illustrate the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of the actual product; for those skilled in the art, it is understandable that some well-known structures and their descriptions in the drawings may be omitted.

[0035] The same or similar numbers in the drawings of the embodiments of the present invention correspond to the same or similar parts; in the description of the present invention, it should be understood that if the terms "upper", "lower", "left", "right", "inside", "outside" and the like indicate an orientation or position relationship based on the orientation or position relationship shown in the drawings, it is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation. Therefore, the terms describing the position relationship in the drawings are only used for illustrative purposes and cannot be understood as limiting this patent. For ordinary technicians in this field, the specific meanings of the above terms can be understood according to specific circumstances.

[0036] In the description of the present invention, unless otherwise expressly specified or limited, when the term "connection" or the like appears to indicate a connection relationship between components, such term should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be internal communication between two components or an interaction between two components. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood in specific circumstances.

[0037] Reference Figure 1-4 As shown, this specific implementation provides the following three embodiments:

[0038] Example 1

[0039] 1. Preparation process:

[0040] Preparation of polyurethane film: A polyurethane solution with a 40% solids content was evenly coated onto 80gsm release paper to a thickness sufficient to form a 15-micron film. The coated release paper was placed in an oven and dried at 80°C for 12 minutes to obtain a polyurethane film of uniform thickness.

[0041] Treatment of release paper: The silicone oil surface of the release paper with a gram weight of 80gsm was treated with a high-frequency corona device. The corona power was set to 3kw. After treatment, the surface tension of the release paper reached 42mN / m.

[0042] Apply polyurethane glue: Mix polyurethane glue and isocyanate curing agent in a 100:20 mass ratio. Apply the mixture to the corona-treated release paper, controlling the coating weight to form a 30gsm glue layer. Dry at 100°C for 15 minutes.

[0043] Adhesive strips and die-cutting: Use a 10mm wide medical non-woven fabric strip and adhere it to one end of the polyurethane film. Finally, die-cut it to make the finished indwelling needle patch.

[0044] 2. Technical effects:

[0045] Under these preparation conditions, the polyurethane film has good flexibility and can fit closely to the skin, and its breathable microporous structure is well maintained, which effectively improves the breathability of the indwelling needle patch and reduces the stuffiness of the skin.

[0046] The release paper after corona treatment adheres firmly to the polyurethane glue. During the production and storage process, the glue layer does not fall off. The release paper is easy to tear off during use without any glue residue.

[0047] The edge strips assist in fixation and removal, making operation easy and reducing the strain on the skin.

[0048] 3. Experimental data:

[0049] Air permeability test: According to GB / T21655.1-2008 "Assessment of moisture absorption and quick-drying properties of textiles Part 1: Single combination test method", the air permeability of the indwelling needle patch is 2000g / (m 2 ·24h).

[0050] Adhesion Test: Following GB / T2792-2014, "Determination of Peel Strength of Adhesive Tapes," the patch was affixed to a standard steel plate. The 180° peel strength reached 250g / 25mm, demonstrating good adhesive adhesion. Skin Sensitivity Test: 50 volunteers underwent a seven-day skin application test. None of the volunteers reported discomfort, demonstrating a significantly lower sensitization rate than traditional patch applications.

[0051] Example 2

[0052] 1. Preparation process:

[0053] Prepare polyurethane film: Take a polyurethane solution with a solid content of 50% and coat it on a 100 gsm release paper. Adjust the coating parameters so that the film thickness after drying is 20 microns. Set the oven temperature to 90°C and the drying time to 15 minutes.

[0054] Treatment of release paper: corona treatment was performed on release paper with a gram weight of 100 gsm, with a corona power of 4 kW. After treatment, the surface tension of the release paper was 45 mN / m.

[0055] Coating polyurethane glue: Mix polyurethane glue and curing agent in a mass ratio of 100:25, apply it on the release paper after corona treatment to form a glue layer with a gram weight of 35gsm, and dry it at 120℃ for 20 minutes.

[0056] Pasting edge strips and die-cutting: Use 15mm wide polyurethane film edge strips to paste on the polyurethane film, and then die-cut.

[0057] 2. Technical effects:

[0058] This polyurethane film not only ensures breathability but also improves mechanical properties and is not easily damaged during daily activities.

[0059] The combination of glue and release paper is more stable, the glue is fully cured, the adhesive layer has good flexibility and cohesion, and the indwelling needle patch is not easy to curl up or fall off during use.

[0060] The overall material compatibility between the edge strip and the indwelling needle patch is good, which further enhances the fixation effect.

[0061] 3. Experimental data:

[0062] Air permeability: tested using ASTM E96-16 "Standard Test Method for Water Vapor Transmission Rate of Packaging Materials by Desiccant Method", the air permeability is 1950g / (m 2 ·24h).

[0063] Glue adhesion: According to GB / T4852-2002 "Test method for initial tack of pressure-sensitive adhesive tapes (rolling ball method)", the initial adhesion reaches a No. 12 steel ball, indicating that the glue has excellent initial adhesion performance.

[0064] Tensile strength of the indwelling needle patch: According to the test of GB / T1040.3-2006 "Determination of tensile properties of plastics Part 3: Test conditions for film and sheeting", the tensile strength is 15MPa, which can meet the use requirements.

[0065] Example 3

[0066] 1. Preparation process:

[0067] Preparation of polyurethane film: A polyurethane solution with a solid content of 35% was coated on a release paper with a gram weight of 60 gsm, and a polyurethane film with a thickness of 12 μm was formed after drying at a temperature of 70° C. for 10 minutes.

[0068] Treatment of release paper: corona treatment of release paper with a grammage of 60gsm, power 2kw, surface tension after treatment is 39mN / m.

[0069] Coating polyurethane glue: Mix polyurethane glue and curing agent in a mass ratio of 100:18, apply it on the release paper to form a glue layer with a gram weight of 25gsm, and dry it at 90℃ for 13 minutes.

[0070] Pasting edge strips and die-cutting: Use medical non-woven fabric edge strips with a width of 8mm, and die-cut after pasting.

[0071] 2. Technical effects:

[0072] The extremely thin polyurethane film makes the indwelling needle patch feel lighter and thinner when attached to the skin, with almost no foreign body sensation, while maintaining good air permeability and moisture permeability.

[0073] After optimized glue formula and corona treatment, the adhesion performance of the glue layer to the release paper and skin is well balanced, ensuring both fixation effect and easy removal.

[0074] The narrow side strip design makes the indwelling needle patch look simpler without affecting its function.

[0075] 3. Experimental data:

[0076] Air permeability: tested according to ISO15106-1:2003 "Plastic film and sheeting - Determination of water vapor transmission rate - Part 1: Humidity sensor method", the air permeability is 2050g / (m 2 ·24h).

[0077] Adhesion between glue and skin: Through a test simulating human skin adhesion and tearing, the 180° peeling force is 200g / 25mm. There is no obvious pain when tearing off, and no residual glue.

[0078] Flexibility of the indwelling needle patch: After 1000 bending tests, there was no film rupture or cracking of the glue layer, indicating good flexibility.

[0079] In summary, the polyurethane glue-based breathable indwelling needle patch provided in this embodiment works as follows:

[0080] 1. Material Action Mechanism: The polyurethane film 1 has a unique microporous structure that allows gas and water vapor to pass through, achieving breathability and moisture permeability. The polyurethane glue tightly bonds to the polar surface of the corona-treated release paper 3 through intermolecular forces. At the same time, the elastic adhesive layer formed after curing can firmly adhere to the skin. When torn off, the cohesive force is greater than the adhesive force, avoiding residual glue.

[0081] 2. Process synergy principle: Corona treatment bombards the release paper surface with high-energy particles, increasing surface roughness and polar groups, improving surface energy, and strengthening the interfacial bonding with the glue. The ratio of glue and curing agent and the optimization of drying parameters ensure that the adhesive layer is completely cured and has stable performance. The setting of the edge strip optimizes the user experience of the application through physical auxiliary effect.

[0082] How to use

[0083] 1. Application step: Provide a tear sheet 301 to tear off the release paper 3, and apply the side of the polyurethane film 1 coated with the polyurethane glue layer 2 to the skin at the patient's indwelling needle puncture site. Adjust the position to make the application flat, and use the side strip 101 to assist in pressing and fixing to ensure that the indwelling needle is completely covered by the glue layer.

[0084] 2. Tearing off step: When using, pinch the edge strip 101 and slowly tear it off to one side. Since the adhesive layer has moderate adhesion to the skin and strong cohesion, the patch can be peeled off as a whole without leaving any adhesive stains or pulling the skin.

[0085] The above are only preferred embodiments of the present invention and do not limit the implementation mode and protection scope of the present invention. For those skilled in the art, it should be aware that all solutions obtained by equivalent substitutions and obvious changes made using the description and illustrations of the present invention should be included in the protection scope of the present invention.

Claims

1. A breathable indwelling needle patch based on polyurethane glue, characterized in that: include: A polyurethane film (1), a polyurethane glue layer (2) coated on one side of the polyurethane film (1), and a release paper (3) covering the polyurethane glue layer (2); the polyurethane film (1) has a thickness of 10-35 microns, the polyurethane glue layer (2) has a grammage of 20-50 gsm, the release paper (3) has a grammage of 50-130 gsm, and the surface of the release paper (3) in contact with the polyurethane glue layer (2) has been subjected to corona treatment.

2. The breathable indwelling needle patch according to claim 1, characterized in that: The polyurethane film (1) is prepared by coating a polyurethane solution on a release paper (3) and drying the resultant solution. The release paper (3) has a gram weight of 50-130 gsm.

3. The breathable indwelling needle patch according to claim 1, characterized in that: It also includes a side strip (101) adhered to one end of the polyurethane film (1), and the side strip (101) is used to assist in fixing and tearing off the indwelling needle; it also includes a tear sheet (301) integrally provided on the corner of the release paper (3), and the tear sheet (301) is used to assist in tearing off the release paper (3) from the polyurethane glue layer (2).

4. The breathable indwelling needle patch according to claim 1, characterized in that: The polyurethane glue layer (2) is formed by mixing polyurethane glue and curing agent in a mass ratio of 100:15-100:35, and then coating and drying.

5. A method for preparing the breathable indwelling needle patch according to any one of claims 1 to 4, characterized in that: The following steps are involved: S1: preparing a polyurethane film (1): coating a polyurethane solution onto a release paper (3) having a grammage of 50-130 gsm, and drying the resulting film to form a polyurethane film (1) having a thickness of 10-35 μm; S2: preparing a release paper (3) for coating: performing a corona treatment on the silicone oil surface of the release paper (3) with a gram weight of 50-130 gsm, with a corona power of 0.5-6 kW; S3: applying polyurethane glue: mixing polyurethane glue and curing agent in a mass ratio of 100:15-100:35 to prepare a mixed solution, applying the mixed solution to the release paper (3) prepared in S2, and drying to form a glue-coated semi-finished product; S4: pasting edge strips and die-cutting: applying the edge strips (101) to the semi-finished polyurethane film (1) obtained by glue coating in S3, and die-cutting into shape.

6. The method for preparing the breathable indwelling needle patch according to claim 5, wherein: The drying temperature in S1 is 60-120° C., and the drying time is 5-20 minutes.

7. The method for preparing the breathable indwelling needle patch according to claim 5, characterized in that: The drying temperature in S3 is 80-150° C., and the drying time is 10-30 minutes.

8. The method for preparing the breathable indwelling needle patch according to claim 5, wherein: The corona treatment of the release paper (3) in S2 adopts a high-frequency corona device, and the surface tension of the release paper (3) after the treatment reaches 38-50 mN / m.

9. The method for preparing the breathable indwelling needle patch according to claim 5, wherein: The solid content of the polyurethane glue in S3 is 100%, and the curing agent is an isocyanate curing agent.

10. The method for preparing the breathable indwelling needle patch according to claim 5, characterized in that: The material of the side strip (101) in S4 is medical non-woven fabric or polyurethane film, and the width of the side strip (101) is 5-20 mm.

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