Improved sodium dichloroisocyanurate powder preparation and preparation method thereof

Abstract

The invention relates to an improved sodium dichloroisocyanurate powder preparation which mainly comprises the following raw materials in percentage by weight: 10-40% of sodium dichloroisocyanurate, 3-20% of an amino compound, 1-5% of organic acid, 3-20% of a catalyst, 10-20% of a corrosion inhibitor, 10-30% of a filler and 0.5-2% of a metal chelating agent. The preparation disclosed by the invention is lower in corrosivity, overcomes the defects of strong odor, great irritation and the like of the existing preparation, prolongs the disinfection time and is better in effect.

Description

Technical Field

[0001] The invention belongs to the technical field of preparation of chlorine-containing disinfectants, in particular to the preparation of solid chlorine preparations, and specifically to an improved sodium dichloroisocyanurate powder preparation and a preparation method thereof. Background Art

[0002] Sodium dichloroisocyanurate (SDIC) is a commonly used disinfectant with strong oxidizing properties, effectively killing various pathogenic microorganisms such as viruses, bacterial spores, and fungi. It is a highly effective bactericide with a wide range of applications. It is also a highly effective oxidizing disinfectant bleaching agent, characterized by a high effective chlorine content, strong bactericidal ability, prolonged release of active chlorine in water, strong storage stability, safety, and convenience. The product is also highly pure, leaving no solid residue after hydrolysis, and resulting in clear water. It represents a significant upgrade to traditional chlorine-containing disinfectants such as bleaching powder and "84" disinfectant, offering the most cost-effective disinfectant. However, it also has significant drawbacks, such as high corrosiveness, a strong odor, and significant respiratory damage. The synthesis of SDIC is currently a major research focus, but its formulation remains largely unexplored.

[0003] Sulfamic acid is an inorganic solid acid formed by replacing the hydroxyl group of sulfuric acid with an amino group. Its chemical formula is NH2SO3H, and its molecular weight is 97.09. It typically appears as white, odorless, rhombic flaky crystals with a relative density of 2.126 and a melting point of 205°C. It is soluble in water and liquid ammonia. At room temperature, solid sulfamic acid is non-hygroscopic and relatively stable as long as it is kept dry and out of contact with water. Its aqueous solution is as strong as hydrochloric acid and sulfuric acid, hence its nickname, solid sulfuric acid. It is non-volatile, odorless, and has low toxicity to humans. In aqueous solution, it can combine with hypochlorous acid to reduce the production of chlorine gas.

[0004] Currently, sodium dichloroisocyanurate powder formulations on the market are limited in variety and functionality. While existing formulations can reduce the risk of corrosion, they still suffer from drawbacks such as a strong odor and short disinfection time. Furthermore, they contain few useful excipients, most of which are fillers, which fail to address the shortcomings of sodium dichloroisocyanurate's chlorine-based formulations. Therefore, there is an urgent need for optimized sodium dichloroisocyanurate powder formulations that are less corrosive and overcome the drawbacks of existing formulations, such as strong odor and irritation. This application was developed with this in mind. Summary of the Invention

[0005] The present invention aims to overcome the shortcomings of the prior art and provide an improved sodium dichloroisocyanurate powder preparation. The preparation is less corrosive and overcomes the shortcomings of the prior art preparations such as strong odor and irritation, while extending the disinfection time and achieving better results.

[0006] The present invention also provides a method for preparing the improved sodium dichloroisocyanurate powder preparation.

[0007] To achieve the above object, the present invention adopts the following technical solutions:

[0008] An improved sodium dichloroisocyanurate powder preparation is mainly composed of the following raw materials in percentage by weight:

[0009] Sodium dichloroisocyanurate 10-40%, aminosulfonic acid 3-20%, organic acid 1-5%, catalyst 3-20%, corrosion inhibitor 10-20%, filler 10-30%, metal chelating agent 0.5-2%.

[0010] Specifically, the amino compound includes but is not limited to any one or more of sulfamic acid, urea, sodium sulfamate, etc.

[0011] Specifically, the organic acid includes but is not limited to any one or more of malic acid, citric acid, fumaric acid, etc.

[0012] Specifically, the catalyst is a material that can provide chloride ions and oxidizing properties, including but not limited to one or more of sodium perborate, sodium percarbonate, potassium persulfate complex salt, sodium chloride, etc.

[0013] Specifically, the corrosion inhibitor includes but is not limited to any one or more of sodium tripolyphosphate, sodium hexametaphosphate, hydroxyethylidene diphosphate, etc.

[0014] Specifically, the filler includes but is not limited to any one of dry sodium sulfate, anhydrous magnesium sulfate, etc.

[0015] Specifically, the metal chelating agent includes but is not limited to any one or two of disodium ethylenediaminetetraacetate, tetrasodium ethylenediaminetetraacetate, and the like.

[0016] The present invention also provides a method for preparing the improved sodium dichloroisocyanurate powder preparation, which is obtained by directly mixing the raw materials in proportion.

[0017] The present invention also provides the use of the improved sodium dichloroisocyanurate powder preparation as a disinfectant (used in a dilution ratio of 1:200-400).

[0018] Compared with the prior art, the present invention has the following advantages and beneficial effects:

[0019] In the preparation of the present invention, sulfamic acid combines with hypochlorous acid to produce sodium N-chlorosulfamate and sodium N,N-dichlorosulfamate in a chlorination reaction, thereby reducing the generation of chlorine gas. A catalyst decomposes the generated chlorine compound into hypochlorous acid, which then continues to participate in the reaction. The chlorination reaction reduces chlorine gas generation while maintaining the disinfection effect. The key innovation of the present invention lies in the balance among the catalyst, sulfamic acid, and dichloroisocyanuric acid.

[0020] In the formulation of the present invention, the catalyst provides chloride ions and oxidizing properties, which react with the amino compound to reduce chlorine gas generation and balance the reaction rate, achieving the same effect. Furthermore, the formulation of the present invention increases product value by reducing odor irritation and corrosivity while also extending the disinfection time, resulting in superior practical results. Compared to existing agents, the formulation of the present invention is less corrosive and less irritating, and extends the disinfection time, resulting in superior results. DETAILED DESCRIPTION

[0021] The technical solution of the present invention is further described in detail below in conjunction with the embodiments, but the protection scope of the present invention is not limited thereto.

[0022] In the following examples, the raw materials used are all common commercial products that can be purchased directly or can be prepared using conventional techniques in the art.

[0023] Example 1

[0024] An improved sodium dichloroisocyanurate powder preparation is composed of the following raw materials in percentage by weight:

[0025] Sodium dichloroisocyanurate 30%, sulfamic acid 10%, organic acid malic acid 3%, catalyst sodium perborate 10%, corrosion inhibitor sodium tripolyphosphate 16%, filler anhydrous magnesium sulfate 30%, metal chelating agent disodium ethylenediaminetetraacetic acid 1%.

[0026] The preparation method of the improved sodium dichloroisocyanurate powder preparation is as follows: directly mix the raw materials to obtain the improved sodium dichloroisocyanurate powder preparation.

[0027] Example 2

[0028] An improved sodium dichloroisocyanurate powder preparation is composed of the following raw materials in percentage by weight:

[0029] Sodium dichloroisocyanurate 30%, aminosulfonic acid 10%, organic acid citric acid 3%, catalyst sodium percarbonate 10%, corrosion inhibitor sodium hexametaphosphate 16%, filler anhydrous magnesium sulfate 30%, metal chelating agent disodium ethylenediaminetetraacetic acid 1%.

[0030] The preparation method of the above-mentioned improved sodium dichloroisocyanurate powder preparation is as described in Example 1.

[0031] Example 3

[0032] An improved sodium dichloroisocyanurate powder preparation is composed of the following raw materials in percentage by weight:

[0033] Sodium dichloroisocyanurate 30%, urea 10%, organic acid fumaric acid 3%, catalyst potassium persulfate complex salt 10%, corrosion inhibitor hydroxyethylidene diphosphate 16%, filler dry sodium sulfate 30%, metal chelating agent tetrasodium ethylenediaminetetraacetic acid 1%.

[0034] The preparation method of the above-mentioned improved sodium dichloroisocyanurate powder preparation is as described in Example 1.

[0035] Example 4

[0036] An improved sodium dichloroisocyanurate powder preparation is composed of the following raw materials in percentage by weight:

[0037] Sodium dichloroisocyanurate 40%, sulfamic acid 15%, organic acid malic acid 2%, catalyst sodium percarbonate 15%, corrosion inhibitor sodium tripolyphosphate 10%, filler anhydrous magnesium sulfate 17%, metal chelating agent disodium ethylenediaminetetraacetic acid 1%.

[0038] The preparation method of the above-mentioned improved sodium dichloroisocyanurate powder preparation is as described in Example 1.

[0039] Example 5

[0040] An improved sodium dichloroisocyanurate powder preparation is composed of the following raw materials in percentage by weight:

[0041] Sodium dichloroisocyanurate 15%, sulfamic acid 20%, organic acid malic acid 4%, catalyst sodium perborate 20%, corrosion inhibitor sodium hexametaphosphate 20%, filler anhydrous magnesium sulfate 20%, metal chelating agent tetrasodium ethylenediaminetetraacetic acid 1%.

[0042] Example 6

[0043] An improved sodium dichloroisocyanurate powder preparation is composed of the following raw materials in percentage by weight:

[0044] Sodium dichloroisocyanurate 30%, aminosulfonic acid 10%, organic acid citric acid 3%, catalyst sodium perborate 10%, corrosion inhibitor hydroxyethylidene diphosphonic acid 16%, filler anhydrous magnesium sulfate 30%, metal chelating agent disodium ethylenediaminetetraacetic acid 1%.

[0045] The preparation method of the above-mentioned improved sodium dichloroisocyanurate powder preparation is as described in Example 1.

[0046] Comparative Example 1

[0047] A sodium dichloroisocyanurate powder preparation, which is composed of the following raw materials in percentage by weight:

[0048] Sodium dichloroisocyanurate 30%, organic acid malic acid 3%, corrosion inhibitor sodium tripolyphosphate 16%, filler anhydrous magnesium sulfate 50%, metal chelating agent disodium ethylenediaminetetraacetic acid 1%.

[0049] This comparative example differs from Example 1 in that no sulfamic acid and catalyst were added.

[0050] The preparation method of the above sodium dichloroisocyanurate powder preparation is as described in Example 1.

[0051] Comparative Example 2

[0052] A sodium dichloroisocyanurate powder preparation, which is composed of the following raw materials in percentage by weight:

[0053] Sodium dichloroisocyanurate 30%, organic acid fumaric acid 3%, corrosion inhibitor hydroxyethylidene diphosphonic acid 16%, filler dry sodium sulfate 50%, metal chelating agent tetrasodium ethylenediaminetetraacetic acid 1%.

[0054] This comparative example differs from Example 3 in that no sulfamic acid and catalyst were added.

[0055] The preparation method of the above sodium dichloroisocyanurate powder preparation is as described in Example 1.

[0056] Comparative Example 3

[0057] A sodium dichloroisocyanurate powder preparation, which is composed of the following raw materials in percentage by weight:

[0058] Sodium dichloroisocyanurate 15%, organic acid malic acid 4%, corrosion inhibitor sodium hexametaphosphate 20%, filler anhydrous magnesium sulfate 60%, metal chelating agent tetrasodium ethylenediaminetetraacetic acid 1%.

[0059] This comparative example differs from Example 5 in that no sulfamic acid and catalyst were added.

[0060] The preparation method of the above sodium dichloroisocyanurate powder preparation is as described in Example 1.

[0061] Performance Testing

[0062] 1.Metal corrosion detection method

[0063] 1.1 Purpose

[0064] Determine the degree of corrosion of disinfectants on various metals to indicate whether due care is required when using them.

[0065] 1.2 Commonly used equipment

[0066] (1) Metal sheet

[0067] Round, 24.0mm diameter, 1.0mm thick, with a 2.0mm diameter hole. The total surface area is approximately 9.80cm2 (including the top, bottom, peripheral surface, and the side of the hole). The finish is 6. The raw materials are as follows:

[0068] Carbon steel (specifications see GB 700-65); copper (specifications see GB 2060-80);

[0069] Aluminum (specifications see GB 1173-74); stainless steel (specifications see GB 1220-75).

[0070] Carbon steel is easily oxidized and rusted and should be stored in oil.

[0071] (2) Soaking container (made of glass, with lid, volume 800ml~1000ml).

[0072] (3) Sandpaper (120 grit water-repellent sandpaper, GB 2477).

[0073] (4) Weighing cup.

[0074] (5) Balance (sensitivity 0.1 mg).

[0075] 1.3 Operating Procedures

[0076] (1) Soak in a surfactant-containing detergent for 10 minutes, thoroughly degrease, and wash. Alternatively, apply magnesium oxide paste to remove the oil and then wash. Use 120-grit sandpaper to remove the oxide layer on both sides and the surrounding surface of the metal sheet, and then rinse with tap water. Measure the diameter, thickness, and pore size of the sheet (accurate to 0.1 mm). Degrease again with anhydrous acetone or anhydrous ethanol. Dry in a 50°C constant temperature box for 1 hour, and weigh it after the temperature drops to room temperature (each metal sheet should be weighed 3 times after the balance returns to zero, accurate to 0.1 mg, and the average value should be taken as the weight before the test. When weighing, wear clean gloves and do not touch the sample directly with your hands.

[0077] (2) Prepare a disinfectant solution for testing at the highest concentration of the disinfectant (1:200 dilution) and use it to soak the test specimens. Each metal piece should be immersed in 200 ml of disinfectant solution.

[0078] (3) Tie the metal specimens with plastic string, label them, number them, and date them, and hang them in the disinfectant. Soak them for 72 hours. For disinfectants that are volatile or have unstable active ingredients, change the disinfectant regularly, depending on the situation, until the 72-hour soak period is complete.

[0079] (4) For each metal, place three specimens for each test. When soaking, if the specimens of the same metal are separated by more than 1 cm, they can be placed in the same container (containing 600 ml of disinfectant).

[0080] (5) After soaking for the specified time, remove the metal sheet, rinse it with tap water, and then use a brush or other soft tools to remove the corrosion products. If there are still corrosion products that cannot be removed, they can be removed according to the following methods described in GB 10124-88:

[0081] Copper sheet: Soak in hydrochloric acid solution (500ml 36%-38% hydrochloric acid plus distilled water to 1000ml, hydrochloric acid specific gravity is 1.19) at room temperature for 1min-3min.

[0082] Carbon steel sheet: Place in a sodium hydroxide solution containing 200g / L zinc powder and boil for 5min to 30min.

[0083] Aluminum sheet: Soak in a chromium trioxide phosphoric acid solution (20g chromium trioxide, 500ml phosphoric acid, distilled water to 1000ml. Phosphoric acid has a specific gravity of 1.69). Heat to 80°C for 5-10 minutes. If the aluminum sheet is still not completely cleaned, soak it in a nitric acid solution (specific gravity 1.42) at room temperature for 1 minute.

[0084] Stainless steel: Soak in a 60°C nitric acid solution (100ml of 66%-68% nitric acid plus distilled water to 1000ml) for 20 minutes. Or soak in a 70°C ammonium citrate solution (150g of ammonium citrate plus distilled water to 1000ml) for 10-60 minutes.

[0085] (6) After removing corrosion products from the metal specimens and cleaning them, dry them with coarse filter paper, place them in a dish lined with filter paper, and place them in a 50°C incubator to dry for 1 hour. Pick them up with tweezers and weigh them on a balance after the temperature drops to room temperature. After the balance returns to zero, weigh them three times and use the average value as the final weight.

[0086] When weighing, as before the test, you should wear clean gloves and avoid direct contact with the sample with your hands (the same applies below).

[0087] (7) When using chemical methods to remove corrosive substances from samples, a corresponding blank control should be set up to correct errors. The blank control samples are surface treated, cleaned, and weighed in the same way as the test group samples, but are not soaked in disinfectant. Afterwards, they are chemically treated, rinsed with water, dried, and weighed in the same way as the test group samples, and their average weight loss is calculated.

[0088] (8) During the entire test, a stainless steel sheet soaked in distilled water should be set up as a control. The weight difference before and after soaking should be less than 0.3 mg. Otherwise, after finding the cause, the entire test should be repeated.

[0089] (9) Test results: observe and record the color change of the metal sheet and express it as the average value of the metal corrosion rate (R). When calculating, the weight loss value of the blank control group sample should be subtracted. The calculation formula is as follows:

[0090]

[0091] R is the corrosion rate, mm / a (millimeter / year); m is the weight of the metal sheet before the test, g; m t is the weight of the metal sheet after the test, g; m kThe weight loss value of the sample after chemical treatment to remove corrosion products, g. If no chemical removal treatment is performed in the test, m is deleted from the formula during calculation. k value; S is the total surface area of ​​the metal sheet, cm 2 ; t is the test time, h; d is the density of the metal material, kg / m 3 .

[0092] 1.4 Corrosion classification standards

[0093] Corrosion rate R (mm / a) level

[0094] <0.0100 basically no corrosion

[0095] 0.0100~<0.100 Mild corrosion

[0096] 0.100~<1.00 Moderate corrosion

[0097] ≥1.00 severe corrosion

[0098] 1.5 Notes

[0099] (1) Each piece of sandpaper can only grind one type of metal. A container of disinfectant can only be used to soak one type of metal.

[0100] (2) Weighing is related to the accuracy of the results and must be carried out carefully. The equipment that comes into contact with the sample must not be greasy or dirty.

[0101] (3) The size and thickness of the metal sheets used should be strictly consistent, and the surface should be polished.

[0102] (4) During the test, if the disinfectant solution needs to be changed, the operation should be done quickly and the sample should not be exposed to the air for too long.

[0103] (5) Metal specimens can only be used once, otherwise the accuracy of the test will be affected.

[0104] (5) The test was carried out at 20℃~25℃.

[0105] 2 Skin irritation test method

[0106] 2.1 Purpose

[0107] To test the irritation / corrosion effect and intensity of disinfectants on the skin of experimental animals.

[0108] 2.2 Experimental animals

[0109] Each test requires at least three healthy rabbits with intact skin.

[0110] 2.3 Operating procedures

[0111] 2.3.1 A complete skin irritation test

[0112] (1) 24 hours before the test, remove the hair on both sides of the spine of the rabbit or guinea pig with a depilatory agent, without damaging the skin. The hair removal area is approximately 3 cm × 3 cm on the left and right sides.

[0113] (2) The next day, the test substance (sample concentration diluted 1:200) was dropped directly onto one side of intact, hairless skin (2.5 cm × 2.5 cm). The other side of hairless skin served as a blank control (or solvent control). The application time was 4 hours. After the test, any remaining test substance was removed with warm water.

[0114] (3) Observe the local skin reaction 1 hour, 24 hours and 48 hours after the removal of the test substance, and perform irritation reaction scoring.

[0115] 2.3.3 Pay attention to the difference between infection and primary irritation reaction. If infection is suspected, repeat testing should be performed.

[0116] 2.4 Evaluation Regulations

[0117] 2.4.1 Primary skin irritation test

[0118] At each observation time point, the animals were scored for skin erythema and edema. The scores of the three animals at each time point were added together and divided by the number of animals to obtain the mean skin irritation score (irritation index) at each time point. The highest skin irritation index was used to assess the level of skin irritation intensity of the test substance.

[0119] 2.4.2 Multiple skin irritation tests

[0120] The average score (irritation index) of each animal per day was calculated according to the following formula to determine the intensity of skin irritation.

[0121]

[0122] Scoring criteria for skin irritation

[0123] Skin irritation reaction score

[0124] Erythema formation:

[0125]

[0126] Edema formation:

[0127]

[0128] Skin irritation intensity classification

[0129]

[0130] 3. Suspension quantitative bactericidal test method

[0131] (1) Use sterile hard water to prepare the solution at a concentration 1.25 times the concentration to be tested (for example, if the concentration of the disinfectant to be evaluated is 200 mg / L, 250 mg / L should be prepared). Place the solution in a water bath at 20°C ± 1°C for later use.

[0132] (2) Prepare the bacterial suspension for the experiment with a concentration of 1×10 8 cfu / ml~5×10 8 cfu / ml.

[0133] (3) For the disinfection test, add 0.5 ml of the test bacterial suspension into a sterile large test tube, then add 0.5 ml of the organic interfering substance (3% bovine serum albumin), mix well, place in a water bath at 20°C ± 1°C for 5 minutes, and then use a sterile pipette to draw 4.0 ml of the disinfectant at the above concentration and inject it into the test tube. Mix quickly and record the time immediately.

[0134] (4) After the test bacteria and disinfectant have interacted for a predetermined time, 0.5 ml of the test bacteria and disinfectant mixture is added to 4.5 ml of sterilized neutralizer (DE neutralization broth) and mixed.

[0135] (5) After the neutralizer is added to each tube of the test bacteria and disinfectant mixture for 10 minutes, 1.0 ml of the sample solution is taken from each tube and the number of viable bacteria is determined by the viable bacteria culture counting method. Two plates are inoculated with each tube of sample solution. If the number of colonies growing on the plate is large, a series of 10-fold dilutions can be performed before viable bacteria culture counting.

[0136] (6) At the same time, trypsin-based saline solution (TPS) was used instead of disinfectant to conduct a parallel experiment as a positive control.

[0137] (7) All samples were cultured in a 37°C incubator after the test, and the bacterial propagules were cultured for 48 h to observe the final results;

[0138] (8) The test was repeated three times. The viable bacterial concentration (cfu / ml) of each group was calculated and converted into a logarithmic value (N). The killing logarithm was then calculated as follows:

[0139] Killing logarithm (KL) = logarithm of the average viable bacteria concentration in the control group (No) - logarithm of the viable bacteria concentration in the test group (Nx)

[0140] When calculating the logarithmic kill value, use two decimal places and round off the numbers. If the average colony count of the disinfection test group after disinfection is less than or equal to 1, its logarithmic kill value is greater than or equal to the logarithmic value of the average viable bacterial concentration of the control group before the test.

[0141] 1. Comparison of metal corrosion tests

[0142] The average corrosion rate of a 200-fold diluted solution of the improved sodium dichloroisocyanurate powder of the present invention (Example 1) on carbon steel was 0.1171 mm / a (moderate corrosion), the average corrosion rate on stainless steel was 0.0000 mm / a (substantially no corrosion), the average corrosion rate on copper was 0.0054 mm / a (substantially no corrosion), and the average corrosion rate on aluminum was 0.0921 mm / a (mild no corrosion). See Tables 1 to 4.

[0143]

[0144] Table 2 Metal corrosion (stainless steel) test results

[0145]

[0146] Table 3 Metal corrosion (copper) test results

[0147]

[0148] Table 4 Metal corrosion (aluminum) test results

[0149]

[0150] 1.1 The average corrosion rate of a 200-fold dilution of ordinary sodium dichloroisocyanurate powder (Comparative Column 1) on carbon steel was 0.1614 mm / a (moderate corrosion), on stainless steel it was 0.0000 mm / a (basically no corrosion), on copper it was 0.1457 mm / a (moderate corrosion), and on aluminum it was 0.09299 mm / a (slightly no corrosion). See Tables 5-8.

[0151]

[0152] Table 6 Metal corrosion (stainless steel) test results

[0153]

[0154] Table 7 Metal Corrosion (Copper) Test Results

[0155]

[0156] Table 8 Metal Corrosion (Aluminum) Test Results

[0157]

[0158] 2. A complete skin irritation test

[0159] 2.1 A single intact skin irritation test of the modified sodium dichloroisocyanurate powder of the present invention (Example 1) at a dilution ratio of 1:200 showed a maximum reaction level of 0, as shown in Table 9. According to the skin irritation intensity grading evaluation standard, it was determined that the modified sodium dichloroisocyanurate powder (Example 1) at a dilution ratio of 1:200 was non-irritating in a single intact skin irritation test on rabbits.

[0160] Table 9 Results of a one-time complete skin irritation test on modified sodium dichloroisocyanurate powder (Example 1) at a dilution of 1:200

[0161]

[0162] 2.2 In the intact skin irritation test with ordinary sodium dichloroisocyanurate powder (Comparative Column 1) at a dilution ratio of 1:200, the highest reaction level was 1.3, as shown in Table 10. According to the skin irritation intensity grading evaluation standard, ordinary sodium dichloroisocyanurate powder (Comparative Column 1) at a dilution ratio of 1:200 was judged to be a mild irritant in the intact skin irritation test on rabbits.

[0163] Table 10 Results of a one-time complete skin irritation test on a 1:200 dilution of common sodium dichloroisocyanurate powder (Comparative Column 1)

[0164]

[0165] 3. Sterilization effect on Escherichia coli after different storage time

[0166] 3.1 The bactericidal efficacy of a diluted solution (1:400) of the improved sodium dichloroisocyanurate powder (Example 1) of the present invention and a diluted solution (1:400) of conventional sodium dichloroisocyanurate powder (Comparative Column 1) against Escherichia coli (ATCC 8099) was essentially the same after 1 hour of storage (sealed and stored at 20°C). However, the bactericidal efficacy differed significantly after 12 hours of storage (sealed and stored at 20°C). According to the technical specifications for disinfectants, the logarithmic value of the bactericidal efficacy of a diluted solution (1:400) of conventional sodium dichloroisocyanurate powder (Comparative Column 1) against Escherichia coli (ATCC 8099) after 12 hours of storage (sealed and stored at 20°C) was less than 5, indicating failure to meet the standards.

[0167] Table 11 Killing effect of modified sodium dichloroisocyanurate powder (Example 1) dilution (1:400) on Escherichia coli (ATCC8099) after 1 hour

[0168]

[0169] Table 12: Effect of modified sodium dichloroisocyanurate powder (Example 1) diluted solution (1:400) on sterilization of Escherichia coli (ATCC 8099) after 12 h of sterilization

[0170]

[0171]

[0172] Table 13 Killing effect of ordinary sodium dichloroisocyanurate powder (comparative column 1) dilution (1:400) on Escherichia coli (ATCC8099) after 1 hour

[0173]

[0174] Table 14 The killing effect of ordinary sodium dichloroisocyanurate powder (comparative column 1) dilution (1:400) on Escherichia coli (ATCC 8099) after 12 hours of sterilization

[0175]

[0176] In summary, the formulation of the present invention increases product value by not only reducing odor irritation and corrosiveness, but also prolonging the disinfection time, resulting in superior practical performance. Compared to existing common reagents, the formulation of the present invention is less corrosive and less irritating, while also extending the disinfection time and achieving superior bactericidal efficacy.

Claims

1. An improved sodium dichloroisocyanurate powder preparation, characterized in that: It is mainly composed of the following raw materials in percentage by weight: Sodium dichloroisocyanurate 10-40%, amino compound 3-20%, organic acid 1-5%, catalyst 3-20%, corrosion inhibitor 10-20%, filler 10-30%, metal chelating agent 0.5-2%.

2. The improved sodium dichloroisocyanurate powder preparation according to claim 1, wherein The amino compound includes any one or more of sulfamic acid, urea, and sodium sulfamate.

3. The improved sodium dichloroisocyanurate powder preparation according to claim 1, wherein The organic acid includes any one or more of malic acid, citric acid and fumaric acid.

4. The improved sodium dichloroisocyanurate powder preparation according to claim 1, wherein The catalyst includes one or more of sodium perborate, sodium percarbonate, potassium persulfate composite salt, and sodium chloride.

5. The improved sodium dichloroisocyanurate powder preparation according to claim 1, wherein The corrosion inhibitor is any one or more of sodium tripolyphosphate, sodium hexametaphosphate, and hydroxyethylidene diphosphate.

6. The improved sodium dichloroisocyanurate powder preparation according to claim 1, wherein The filler is any one of dry sodium sulfate and anhydrous magnesium sulfate.

7. The improved sodium dichloroisocyanurate powder preparation according to claim 1, wherein The metal chelating agent is any one or two of disodium ethylenediaminetetraacetate and tetrasodium ethylenediaminetetraacetate.

8. The method for preparing the improved sodium dichloroisocyanurate powder preparation according to any one of claims 1 to 7, characterized in that: Directly mix the raw materials in proportion to obtain the product.

9. Use of the improved sodium dichloroisocyanurate powder preparation according to any one of claims 1 to 7 as a disinfectant.

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