Non-woven fabric for medical treatment and public health and preparation method thereof

Abstract

The invention discloses a non-woven fabric for medical treatment and public health and a preparation method thereof, and the non-woven fabric is prepared from the following components in parts by weight: 25-45 parts of polylactic acid fiber and 55-75 parts of modified cotton fiber; the modified cotton fiber is obtained by carrying out formylation on cotton fiber and then carrying out graft modification on the cotton fiber, a wormwood essential oil clathrate compound and chitosan; the polylactic acid fibers and the modified cotton fibers are optimally proportioned and combined, so that perfect balance of biological safety and functionality is realized, and the non-woven fabric has lasting broad-spectrum antibacterial, anti-inflammatory and antioxidant activity, keeps excellent air permeability, moisture absorption and comfort level, and has a good application prospect. In addition, the health protection device has a longer effective use cycle and more stable functional characteristics, and can meet health protection requirements in various scenes such as hospitals, clinics and home nursing.

Description

Technical Field

[0001] The present invention relates to the technical field of non-woven fabrics, and in particular to a non-woven fabric for medical and sanitary use and a preparation method thereof. Background Art

[0002] Nonwoven fabrics are formed from oriented or randomly arranged fibers through friction, bonding, or heat-melting. They offer lightweight, breathable, insulating, and filtering properties. Based on the forming process, nonwovens can be categorized into various types, including spunlace, meltblown, spunbond, needlepunch, and airlaid. Each process imparts distinct physical properties and application advantages. Spunlace nonwovens are widely used in the medical and healthcare sectors due to their softness, drape, and breathability. Meltblown nonwovens, however, are a core material for medical masks due to their excellent filtering properties.

[0003] Medical nonwovens serve as essential building blocks for protection, isolation, and nursing care, finding widespread use in surgical gowns, masks, sterile dressings, medical sheets, isolation suits, Band-Aids, diapers, and more. Compared to traditional textile fabrics, nonwovens offer advantages such as shorter production cycles, higher cost-effectiveness, and greater customizability. Medical-grade nonwovens must meet stringent requirements for sterility, biocompatibility, breathability, strength, and comfort, and must pass specific medical material certification standards.

[0004] Traditional medical nonwovens are primarily made from petroleum-based synthetic fibers such as polypropylene (PP) and polyester (PET). These fabrics have mature production processes, enabling large-scale, automated production. While they offer advantages such as low production costs, excellent mechanical properties, and superior processing performance, they suffer from common issues such as poor biodegradability, severe environmental pollution, limited functionality, and insufficient skin comfort. As the medical industry continues to demand greener, more functional, safer, and more sustainable materials, the development of safe, green, and multifunctional medical nonwovens has become an inevitable trend in the industry.

[0005] In recent years, research into improving the functionality of sanitary nonwovens has focused on antibacterial and antimicrobial properties. Common functional modification methods include adding metal ions such as silver and copper, inorganic nanomaterials such as titanium dioxide and zinc oxide, or organic antimicrobial agents such as quaternary ammonium salts to nonwovens.

[0006] CN114737389A discloses a household antibacterial non-woven fabric and a preparation method thereof. The non-woven fabric comprises the following raw materials in parts by weight: 80-100 parts of polypropylene fiber, 8-10 parts of a binder, and 20-30 parts of an antibacterial agent; the polypropylene fiber is made of polypropylene particles, a softener, a plasticizer, and an anti-ultraviolet agent; the antibacterial agent is made of zeolite molecular sieve powder, carrageenan, an antibacterial substance, and water; the antibacterial substance comprises nano-silver powder and also includes cinnamic acid or sorbic acid.

[0007] However, this type of modification often has problems such as toxicity risks, side reactions or easy loss of active components, and short-lasting antibacterial effects, making it difficult to meet the requirements of high-standard medical scenarios.

[0008] On the other hand, natural products such as Chinese herbal essential oils and biopolymer materials have been widely studied in recent years as functional components of medical non-woven fabrics due to their good biocompatibility, diverse functions and abundant sources. For example, wormwood essential oil has significant antibacterial and anti-inflammatory effects, and chitosan has both biodegradability and broad-spectrum antibacterial activity. However, how to achieve efficient loading and sustained release of these active ingredients, as well as to ensure the comprehensive physical properties and economic applicability of the materials, remains a major challenge in the current technical field. At present, common methods for functionalizing non-woven fabrics include blending modification, surface coating, and post-finishing treatment, but traditional physical adsorption methods make it difficult to achieve firm binding and sustained release of active ingredients.

[0009] Therefore, developing a non-woven fabric for medical and sanitary use that is highly effective in antibacterial, safe and degradable, comfortable and environmentally friendly, while taking into account the green nature of the process and the feasibility of industrialization, has important practical significance and broad application prospects for improving the overall performance and market competitiveness of medical and sanitary products. Summary of the Invention

[0010] In order to address the shortcomings of the prior art, the purpose of the present invention is to provide a non-woven fabric for medical and sanitary use and a preparation method thereof. The present invention achieves a perfect balance between biosafety and functionality through an optimized ratio combination of polylactic acid fiber and modified cotton fiber. The non-woven fabric has long-lasting broad-spectrum antibacterial, anti-inflammatory and antioxidant activity, while maintaining excellent air permeability, moisture absorption and comfort. It also has a longer effective use cycle and more stable functional properties, which can meet the health protection needs in various scenarios such as hospitals, clinics and home care.

[0011] In order to achieve the above object, the present invention adopts the following technical solutions:

[0012] A non-woven fabric for medical and sanitary use, characterized in that it is made of the following components, measured by weight: 25-45 parts of polylactic acid fiber and 55-75 parts of modified cotton fiber; the modified cotton fiber is obtained by modifying cotton fiber after it is aldehyde-modified and then grafted with an wormwood essential oil inclusion compound and chitosan.

[0013] Preferably, the length of the polylactic acid fiber is 15 to 20 mm, and the fineness is 0.6 to 1.1D.

[0014] Preferably, the modified cotton fiber is prepared by the following method steps:

[0015] (1) immersing cotton fiber in a sodium hydroxide aqueous solution, stirring to react, washing until neutral, then immersing in a potassium periodate aqueous solution, reacting in the dark, removing the product, washing, and drying to obtain formaldehyde-modified cotton fiber;

[0016] Aldehydation of cotton fibers: In a sodium hydroxide solution, alkaline treatment partially breaks the hydrogen bonds between cellulose molecules, causing the cellulose structure to swell and expose more hydroxyl active sites. Subsequently, potassium periodate, a selective oxidant, introduces aldehyde functional groups onto the cellulose chains, resulting in aldehydated cotton fibers.

[0017] Preferably, in step (1), the length of the cotton fiber is 15 to 30 mm, and the fineness is 1.1 to 1.6D.

[0018] Preferably, in step (1), the concentration of the sodium hydroxide aqueous solution is 10-20wt%, and the concentration of the potassium periodate aqueous solution is 5-10wt%; the dosage ratio of the cotton fiber, the sodium hydroxide aqueous solution, and the potassium periodate aqueous solution is 10g:150-250mL:100-200mL.

[0019] Preferably, in step (1), the stirring reaction conditions are 30-60° C. and 0.5-2 h; the light-proof reaction conditions are 25-55° C. and 200-300 r / min in the dark and stirring reaction for 2-8 h; the product is washed 3-5 times with deionized water, then washed once with ethanol, and dried at 40-60° C. for 3-6 h.

[0020] (2) adding polyethyleneimine-cyclodextrin to deionized water, stirring and dissolving to obtain a polyethyleneimine-cyclodextrin aqueous solution; adding wormwood essential oil to ethanol, stirring and dissolving to obtain a wormwood essential oil alcohol solution; slowly adding the wormwood essential oil alcohol solution dropwise to the polyethyleneimine-cyclodextrin aqueous solution under stirring, conducting a closed reflux reaction, rotary evaporating the product to remove ethanol, and freeze-drying to obtain a wormwood essential oil inclusion compound;

[0021] Inclusion of wormwood essential oil: Polyethyleneimine-cyclodextrin is a bifunctional modified structure, in which the β-cyclodextrin part provides a truncated cone-shaped hydrophobic cavity, while the polyethyleneimine part contains a large number of amino groups capable of chemical reactions. When the alcohol solution of wormwood essential oil is mixed with the polyethyleneimine-cyclodextrin aqueous solution, the hydrophobic active molecules in the wormwood essential oil (such as eucalyptol, thujone, etc.) spontaneously enter the hydrophobic cavity of β-cyclodextrin and form a host-guest inclusion complex through van der Waals forces, hydrophobic interactions and hydrogen bonds. At the same time, the hydrophilicity of the polyethyleneimine part in polyethyleneimine-cyclodextrin enhances the stability and dispersibility of the entire structure in water, making the inclusion process more efficient.

[0022] Preferably, in step (2), the dosage ratio of polyethyleneimine-cyclodextrin and deionized water is 3-7 g:80-150 mL, the dosage ratio of wormwood essential oil and ethanol is 0.5-2 g:15-30 mL; the dosage ratio of polyethyleneimine-cyclodextrin and wormwood essential oil is 3-8:1.

[0023] Preferably, in step (2), the wormwood essential oil alcohol solution is slowly added dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a rate of 0.5 to 2 mL / min, and ultrasonic treatment is performed for 5 to 10 minutes every 10 to 20 minutes; the reflux reaction conditions are stirring and reflux reaction at 35 to 50° C. for 3 to 6 hours; the product is subjected to reduced pressure rotary evaporation to remove ethanol, and then freeze-dried for 12 to 24 hours.

[0024] (3) Chitosan is added to an acetic acid aqueous solution and stirred to dissolve, then immersed in the formaldehyde-modified cotton fiber and stirred to disperse, and finally the wormwood essential oil inclusion compound is added, mixed evenly, stirred to react, and the product is fished out, washed, and dried to obtain modified cotton fiber.

[0025] Functionalization of cotton fibers: Two types of Schiff base reactions occur in this step, introducing a dual antibacterial system. After chitosan is protonated and dissolved in an aqueous acetic acid solution, the amino groups on its molecular chain undergo a nucleophilic addition reaction with some of the aldehyde groups on the surface of the aldehyde-modified cotton fibers, forming Schiff base covalent bonds and chemically bonding the cotton fibers to chitosan. At the same time, the amino groups contained in the polyethyleneimine portion of the added wormwood essential oil inclusion complex also undergo the same Schiff base reaction with the remaining aldehyde groups on the aldehyde-modified cotton fibers, forming a second layer of chemical bonding network.

[0026] Preferably, in step (3), the concentration of the acetic acid aqueous solution is 1-2 wt%, and the amount ratio of chitosan, acetic acid aqueous solution, aldehyde-modified cotton fiber, and wormwood essential oil inclusion complex is 1.5-4.5 g: 80-150 mL: 10 g: 2-5 g.

[0027] Preferably, in step (3), the stirring and dissolving conditions are stirring at 45-60° C. until completely dissolved to obtain a transparent viscous solution; the stirring and dispersion conditions are stirring at 40-55° C. and 150-300 r / min for 0.5-2 h; the stirring reaction conditions are stirring at 40-55° C. and 150-300 r / min for 4-10 h; the product is washed with deionized water 3-5 times, then washed once with ethanol, and vacuum dried at 40-60° C. for 6-12 h.

[0028] Preferably, the non-woven fabric has a gram weight of 50 to 120 g / m 2 .

[0029] The present invention also claims protection for a method for preparing the non-woven fabric for medical and sanitary use, comprising the following steps: mixing polylactic acid fibers and modified cotton fibers and combing them to form a fiber web, and then hydroentangling and reinforcing them to obtain the non-woven fabric.

[0030] Compared with the prior art, the present invention has the following beneficial effects:

[0031] 1. The present invention provides a non-woven fabric for medical and sanitary use. Polylactic acid fiber is a biodegradable material, which is not only environmentally friendly and non-toxic, but also has good mechanical strength and toughness, and provides the necessary structural support and physical properties for the non-woven fabric. The modified cotton fiber gives the material excellent functional properties, which are mainly reflected in: wormwood essential oil provides broad-spectrum antibacterial, anti-inflammatory and antioxidant activities; the chitosan layer provides sustained antibacterial effects and good biocompatibility; the natural cotton fiber base ensures the product's breathability, moisture absorption and comfort. The precise control of the ratio of the two fibers ensures that the non-woven fabric maximizes the effect of the functional components while maintaining sufficient strength. It is suitable for medical and sanitary products that come into direct contact with the human body, and achieves a perfect combination of environmental protection and high-efficiency functions.

[0032] 2. The present invention provides a modified cotton fiber. First, the potassium periodate oxidation process introduces aldehyde active sites, providing a chemical bonding basis for subsequent reactions; secondly, the inclusion complex formed by polyethyleneimine-cyclodextrin and wormwood essential oil not only improves the stability and water solubility of the essential oil, but also achieves a sustained release effect of the active ingredients through the cavity structure of cyclodextrin. The active ingredients such as eucalyptol, sabinene, and thujone in wormwood essential oil can destroy bacterial cell walls and cell membranes, inhibit protein synthesis, and show broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. At the same time, chitosan can inhibit the growth of bacteria through its protonated amino group (-NH3 + ) interacts with the negatively charged components on the cell walls of microorganisms, destroying the integrity of the cell membrane and hindering its normal function. It can also chelate the metal ions required for microbial growth, forming a physical barrier to prevent the reproduction of pathogens. The synergistic antibacterial effect of chitosan and wormwood essential oil produces a broader-spectrum and more lasting antibacterial effect. In addition, the double chemical bonding network (chitosan and polyethyleneimine can both form Schiff base bonds with formaldehyde-treated cotton fibers) ensures the firm attachment of functional components, while the three-dimensional network structure formed by chitosan provides additional physical encapsulation, further enhancing the load stability and sustained-release performance of wormwood essential oil on the fiber surface, so that the product can maintain stable antibacterial and antioxidant effects after repeated use and washing, fully meeting the high standards for medical and sanitary products. DETAILED DESCRIPTION

[0033] In order to make the purpose, technical solutions and advantages of the present invention clearer, the present invention is further described in detail below in conjunction with the embodiments. Of course, the specific embodiments described here are only used to explain the present invention and are not used to limit the present invention.

[0034] Unless otherwise specified, the chemical reagents and materials in the present invention are purchased from commercial sources or synthesized from commercially purchased raw materials.

[0035] Polylactic acid fiber was purchased from Hengtian Fiber Group Co., Ltd.

[0036] Chitosan was purchased from Shanghai Aladdin Biochemical Technology Co., Ltd. with a deacetylation degree of ≥95% and a viscosity of 100–200 MPa·s;

[0037] β-Cyclodextrin was purchased from Shanghai Yuanye Biotechnology Co., Ltd., catalog number: S11010;

[0038] Artemisia argyi essential oil was purchased from Nanyang Wanchuntang Company.

[0039] A method for preparing a non-woven fabric for medical and sanitary use comprises the following steps:

[0040] (1) 10 g of cotton fiber was immersed in 150-250 mL of a 10-20 wt% sodium hydroxide aqueous solution, stirred at 30-60° C. for 0.5-2 h, washed until neutral, and then immersed in 100-200 mL of a 5-10 wt% potassium periodate aqueous solution, stirred at 25-55° C. and 200-300 r / min in the dark for 2-8 h, the product was removed, washed with deionized water 3-5 times, then washed once with ethanol, and dried at 40-60° C. for 3-6 h to obtain aldehyde-modified cotton fiber;

[0041] (2) Add 3-7 g of polyethyleneimine-cyclodextrin to 80-150 mL of deionized water, stir and dissolve to obtain a polyethyleneimine-cyclodextrin aqueous solution; add 0.5-2 g of wormwood essential oil to 15-30 mL of ethanol, stir and dissolve to obtain a wormwood essential oil alcohol solution; slowly add the wormwood essential oil alcohol solution dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a rate of 0.5-2 mL / min under stirring, perform ultrasonic treatment for 5-10 minutes every 10-20 minutes, stir and reflux for 3-6 hours at 35-50°C in a sealed manner, remove ethanol from the product by vacuum rotary evaporation, and then freeze-dry for 12-24 hours to obtain a wormwood essential oil inclusion complex; the dosage ratio of polyethyleneimine-cyclodextrin to wormwood essential oil is 3-8:1;

[0042] (3) adding 1.5-4.5 g of chitosan to 80-150 mL of a 1-2 wt% acetic acid aqueous solution, stirring at 45-60° C. until completely dissolved, then immersing 10 g of formaldehyde-modified cotton fiber, stirring at 40-55° C. and 150-300 r / min for 0.5-2 h, finally adding 2-5 g of wormwood essential oil inclusion compound, mixing evenly, stirring at 40-55° C. and 150-300 r / min for 4-10 h, removing the product, washing it with deionized water 3-5 times, then washing it with ethanol once, and vacuum drying it at 40-60° C. for 6-12 h to obtain modified cotton fiber;

[0043] (4) 25-45 parts of polylactic acid fiber and 55-75 parts of modified cotton fiber are mixed and combed to form a fiber web, and then hydroentangled to obtain a fiber web of 50-120 g / m 2 Heavy non-woven fabric for medical and sanitary use.

[0044] The polyethyleneimine-cyclodextrin is prepared by the following method steps: dissolving 2.1g of β-cyclodextrin and 4.0g of N,N'-carbonyldiimidazole in 25mL of DMF and mixing them under a nitrogen atmosphere at room temperature for 1 hour to obtain mixture 1; placing mixture 1 in -2°C ether for 1 hour, filtering to obtain N,N'-carbonyldiimidazole-β-cyclodextrin; drying N,N'-carbonyldiimidazole-β-cyclodextrin and dissolving it in 25mL of DMF to obtain mixture 2; dissolving 7.5g of polyethyleneimine in 15mL of DMF to obtain mixture 3; mixing mixture 2 and 1.5mL of triethylamine, and then adding the mixture dropwise to mixture 3 at 40 drops / min, leaving it for 5 hours to obtain mixture 4, dialyzing it with deionized water for 3 days, and freeze-drying it to obtain the polyethyleneimine-cyclodextrin.

[0045] The present invention will be further described below with reference to specific examples.

[0046] Example 1

[0047] A method for preparing a non-woven fabric for medical and sanitary use comprises the following steps:

[0048] (1) 10 g of cotton fiber was immersed in 200 mL of a 15 wt% sodium hydroxide aqueous solution, stirred at 50° C. for 1.5 h, washed until neutral, and then immersed in 150 mL of a 7.5 wt% potassium periodate aqueous solution, stirred at 55° C. and 250 r / min in the dark for 2 h. The product was removed, washed four times with deionized water, then washed once with ethanol, and dried at 50° C. for 4.5 h to obtain formaldehyde-modified cotton fiber;

[0049] (2) 7 g of polyethyleneimine-cyclodextrin was added to 120 mL of deionized water, and the mixture was stirred and dissolved to obtain a polyethyleneimine-cyclodextrin aqueous solution; 2 g of wormwood essential oil was added to 25 mL of ethanol, and the mixture was stirred and dissolved to obtain a wormwood essential oil alcohol solution; the wormwood essential oil alcohol solution was slowly added dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a rate of 1.5 mL / min under stirring, and ultrasonic treatment was performed for 8 min every 15 min, and the mixture was stirred and refluxed at 50° C. for 3 h, and the product was evaporated under reduced pressure to remove ethanol, and then freeze-dried for 18 h to obtain a wormwood essential oil inclusion compound;

[0050] (3) 4.5 g of chitosan was added to 120 mL of a 1.5 wt% acetic acid aqueous solution and stirred at 60° C. until completely dissolved. Then, 10 g of formaldehyde-modified cotton fiber was immersed in the mixture and stirred at 55° C. and 200 r / min for 0.5 h. Finally, 5 g of wormwood essential oil inclusion compound was added and mixed evenly. The mixture was stirred at 55° C. and 200 r / min for 4 h. The product was removed and washed with deionized water 4 times, then washed with ethanol once, and vacuum dried at 50° C. for 9 h to obtain modified cotton fiber.

[0051] (4) 2.5 kg of polylactic acid fiber and 7.5 kg of modified cotton fiber were mixed and combed to form a fiber web, and then hydroentangled to obtain 100 g / m 2 Heavy non-woven fabric for medical and sanitary use.

[0052] Example 2

[0053] A method for preparing a non-woven fabric for medical and sanitary use comprises the following steps:

[0054] (1) 10 g of cotton fiber was immersed in 200 mL of a 15 wt% sodium hydroxide aqueous solution, stirred at 50° C. for 1.5 h, washed until neutral, and then immersed in 150 mL of a 7.5 wt% potassium periodate aqueous solution, stirred at 40° C. and 250 r / min in the dark for 5 h. The product was removed, washed four times with deionized water, then washed once with ethanol, and dried at 50° C. for 4.5 h to obtain formaldehyde-modified cotton fiber;

[0055] (2) Add 5 g of polyethyleneimine-cyclodextrin to 120 mL of deionized water, stir and dissolve to obtain a polyethyleneimine-cyclodextrin aqueous solution; add 1 g of wormwood essential oil to 25 mL of ethanol, stir and dissolve to obtain a wormwood essential oil alcohol solution; slowly add the wormwood essential oil alcohol solution dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a rate of 1.5 mL / min under stirring, perform ultrasonic treatment for 8 minutes every 15 minutes, stir and reflux for 5 hours at 40°C in a sealed manner, remove ethanol from the product by vacuum rotary evaporation, and then freeze-dry for 18 hours to obtain a wormwood essential oil inclusion compound;

[0056] (3) 3 g of chitosan was added to 120 mL of a 1.5 wt% acetic acid aqueous solution and stirred at 50° C. until completely dissolved. Then, 10 g of formaldehyde-modified cotton fiber was immersed in the mixture and stirred at 50° C. and 200 r / min for 1 h. Finally, 3.5 g of wormwood essential oil inclusion compound was added and mixed evenly. The mixture was stirred at 45° C. and 200 r / min for 7 h. The product was removed and washed with deionized water 4 times, then washed with ethanol once, and vacuum dried at 50° C. for 9 h to obtain modified cotton fiber.

[0057] (4) 3.5 kg of polylactic acid fiber and 6.5 kg of modified cotton fiber were mixed and combed to form a fiber web, and then hydroentangled to obtain 100 g / m 2Heavy non-woven fabric for medical and sanitary use.

[0058] Example 3

[0059] A method for preparing a non-woven fabric for medical and sanitary use comprises the following steps:

[0060] (1) 10 g of cotton fiber was immersed in 200 mL of a 15 wt% sodium hydroxide aqueous solution, stirred at 50° C. for 1.5 h, washed until neutral, and then immersed in 150 mL of a 7.5 wt% potassium periodate aqueous solution, stirred at 25° C. and 250 r / min in the dark for 8 h. The product was removed, washed four times with deionized water, then washed once with ethanol, and dried at 50° C. for 4.5 h to obtain formaldehyde-modified cotton fiber;

[0061] (2) 3 g of polyethyleneimine-cyclodextrin was added to 120 mL of deionized water, and the mixture was stirred and dissolved to obtain a polyethyleneimine-cyclodextrin aqueous solution; 0.5 g of wormwood essential oil was added to 25 mL of ethanol, and the mixture was stirred and dissolved to obtain a wormwood essential oil alcohol solution; the wormwood essential oil alcohol solution was slowly added dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a rate of 1.5 mL / min under stirring, and ultrasonic treatment was performed for 8 min every 15 min, and the mixture was stirred and refluxed at 35 ° C for 6 h, and the product was evaporated under reduced pressure to remove ethanol, and then freeze-dried for 18 h to obtain a wormwood essential oil inclusion compound;

[0062] (3) 1.5 g of chitosan was added to 120 mL of a 1.5 wt% acetic acid aqueous solution and stirred at 45° C. until completely dissolved. Then, 10 g of formaldehyde-modified cotton fiber was immersed in the mixture and stirred at 40° C. and 200 r / min for 0.5 h. Finally, 2 g of wormwood essential oil inclusion compound was added and mixed evenly. The mixture was stirred at 40° C. and 200 r / min for 10 h. The product was removed and washed with deionized water 4 times, then washed with ethanol once, and vacuum dried at 50° C. for 9 h to obtain modified cotton fiber.

[0063] (4) 4.5 kg of polylactic acid fiber and 5.5 kg of modified cotton fiber were mixed and combed to form a fiber web, and then hydroentangled to obtain 100 g / m 2 Heavy non-woven fabric for medical and sanitary use.

[0064] Comparative Example 1

[0065] A method for preparing a non-woven fabric for medical and sanitary use comprises the following steps:

[0066] (1) 10 g of cotton fiber was immersed in 200 mL of a 15 wt% sodium hydroxide aqueous solution, stirred at 50° C. for 1.5 h, washed until neutral, and then immersed in 150 mL of a 7.5 wt% potassium periodate aqueous solution, stirred at 55° C. and 250 r / min in the dark for 2 h. The product was removed, washed four times with deionized water, then washed once with ethanol, and dried at 50° C. for 4.5 h to obtain formaldehyde-modified cotton fiber;

[0067] (2) 7 g of polyethyleneimine-cyclodextrin was added to 120 mL of deionized water, and the mixture was stirred and dissolved to obtain a polyethyleneimine-cyclodextrin aqueous solution; 2 g of wormwood essential oil was added to 25 mL of ethanol, and the mixture was stirred and dissolved to obtain a wormwood essential oil alcohol solution; the wormwood essential oil alcohol solution was slowly added dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a rate of 1.5 mL / min under stirring, and ultrasonic treatment was performed for 8 min every 15 min, and the mixture was stirred and refluxed at 50° C. for 3 h, and the product was evaporated under reduced pressure to remove ethanol, and then freeze-dried for 18 h to obtain a wormwood essential oil inclusion compound;

[0068] (3) 10 g of aldehyde-modified cotton fiber was immersed in 120 mL of 1.5 wt% acetic acid aqueous solution, stirred at 55 ° C and 200 r / min for 0.5 h, and finally 5 g of wormwood essential oil inclusion compound was added, mixed evenly, and stirred at 55 ° C and 200 r / min for 4 h. The product was removed, washed with deionized water 4 times, then washed with ethanol once, and vacuum dried at 50 ° C for 9 h to obtain modified cotton fiber;

[0069] (4) 2.5 kg of polylactic acid fiber and 7.5 kg of modified cotton fiber were mixed and combed to form a fiber web, and then hydroentangled to obtain 100 g / m 2 Heavy non-woven fabric for medical and sanitary use.

[0070] Comparative Example 2

[0071] A method for preparing a non-woven fabric for medical and sanitary use comprises the following steps:

[0072] (1) 10 g of cotton fiber was immersed in 200 mL of a 15 wt% sodium hydroxide aqueous solution, stirred at 50° C. for 1.5 h, washed until neutral, and then immersed in 150 mL of a 7.5 wt% potassium periodate aqueous solution, stirred at 55° C. and 250 r / min in the dark for 2 h. The product was removed, washed four times with deionized water, then washed once with ethanol, and dried at 50° C. for 4.5 h to obtain formaldehyde-modified cotton fiber;

[0073] (3) 4.5 g of chitosan was added to 120 mL of a 1.5 wt% acetic acid aqueous solution and stirred at 60°C until completely dissolved. Then, 10 g of formaldehyde-modified cotton fiber was immersed in the mixture and stirred at 55°C and 200 r / min for 0.5 h. The mixture was stirred at 55°C and 200 r / min for 4 h. The product was removed, washed four times with deionized water, then washed once with ethanol, and dried in vacuo at 50°C for 9 h to obtain modified cotton fiber.

[0074] (4) 2.5 kg of polylactic acid fiber and 7.5 kg of modified cotton fiber were mixed and combed to form a fiber web, and then hydroentangled to obtain 100 g / m 2 Heavy non-woven fabric for medical and sanitary use.

[0075] Comparative Example 3

[0076] A method for preparing a non-woven fabric for medical and sanitary use comprises the following steps:

[0077] (1) 10 g of cotton fiber was immersed in 200 mL of a 15 wt% sodium hydroxide aqueous solution, stirred at 50° C. for 1.5 h, and washed until neutral to obtain pretreated cotton fiber;

[0078] (2) 7 g of polyethyleneimine-cyclodextrin was added to 120 mL of deionized water, and the mixture was stirred and dissolved to obtain a polyethyleneimine-cyclodextrin aqueous solution; 2 g of wormwood essential oil was added to 25 mL of ethanol, and the mixture was stirred and dissolved to obtain a wormwood essential oil alcohol solution; the wormwood essential oil alcohol solution was slowly added dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a rate of 1.5 mL / min under stirring, and ultrasonic treatment was performed for 8 min every 15 min, and the mixture was stirred and refluxed at 50° C. for 3 h, and the product was evaporated under reduced pressure to remove ethanol, and then freeze-dried for 18 h to obtain a wormwood essential oil inclusion compound;

[0079] (3) 4.5 g of chitosan was added to 120 mL of a 1.5 wt% acetic acid aqueous solution and stirred at 60° C. until completely dissolved. Then, 10 g of pretreated cotton fiber was immersed in the mixture and stirred at 55° C. and 200 r / min for 0.5 h. Finally, 5 g of wormwood essential oil inclusion compound was added and mixed evenly. The mixture was stirred at 55° C. and 200 r / min for 4 h. The product was removed and washed 4 times with deionized water and then once with ethanol. The modified cotton fiber was dried in vacuo at 50° C. for 9 h to obtain the modified cotton fiber.

[0080] (4) 2.5 kg of polylactic acid fiber and 7.5 kg of modified cotton fiber were mixed and combed to form a fiber web, and then hydroentangled to obtain 100 g / m 2 Heavy non-woven fabric for medical and sanitary use.

[0081] The breaking strength and elongation were tested with reference to GB / T 24218.3-2010 “Textiles — Test methods for nonwovens — Part 3: Determination of breaking force and elongation at break (Strip method)”; the air permeability was tested with reference to GB / T 24218.15-2018 “Textiles — Test methods for nonwovens — Part 15: Determination of air permeability”; the softness was tested with reference to GB / T 8942-2016 “Determination of the softness of paper”. The softness value was less than 200 mN, which was comparable to the value of traditional toilet paper, indicating good softness. Specific data are shown in Table 1.

[0082] Table 1 Test results of mechanical properties, air permeability and softness of nonwoven fabrics

[0083]

[0084] The initial antibacterial rate was tested according to GB / T 20944.3-2008 "Evaluation of Antimicrobial Properties of Textiles - Part 3: Oscillation Method." The nonwoven fabric was repeatedly washed 50 times with a commercially available detergent (2 hours of soaking, 30 minutes of washing, and 3 hours of drying under a fluorescent lamp). The antibacterial rate was then retested, and the long-term antibacterial rate was calculated (long-term antibacterial rate = (initial antibacterial rate - antibacterial rate after repeated washing) / initial antibacterial rate × 100%). Specific data are shown in Table 2.

[0085] Table 2 Test results of antibacterial properties of non-woven fabrics

[0086]

[0087] The above description is only a preferred specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any technician familiar with the technical field, within the technical scope disclosed by the present invention, who makes equivalent replacements or changes based on the technical solution and inventive concept of the present invention, should be covered by the scope of protection of the present invention.

Claims

1. A non-woven fabric for medical and sanitary use, characterized in that: The invention is prepared from the following components in parts by weight: 25-45 parts of polylactic acid fiber and 55-75 parts of modified cotton fiber; the modified cotton fiber is obtained by grafting modified cotton fiber with wormwood essential oil inclusion compound and chitosan after aldehyde group modification.

2. The medical and sanitary nonwoven fabric according to claim 1, characterized in that: The modified cotton fiber is prepared by the following method steps: (1) immersing cotton fiber in a sodium hydroxide aqueous solution, stirring to react, washing until neutral, then immersing in a potassium periodate aqueous solution, reacting in the dark, removing the product, washing, and drying to obtain formaldehyde-modified cotton fiber; (2) adding polyethyleneimine-cyclodextrin to deionized water, stirring and dissolving to obtain a polyethyleneimine-cyclodextrin aqueous solution; adding wormwood essential oil to ethanol, stirring and dissolving to obtain a wormwood essential oil alcohol solution; slowly adding the wormwood essential oil alcohol solution dropwise to the polyethyleneimine-cyclodextrin aqueous solution under stirring, conducting a closed reflux reaction, rotary evaporating the product to remove ethanol, and freeze-drying to obtain a wormwood essential oil inclusion compound; (3) Chitosan is added to an acetic acid aqueous solution and stirred to dissolve, then immersed in the formaldehyde-modified cotton fiber and stirred to disperse, and finally the wormwood essential oil inclusion compound is added, mixed evenly, stirred to react, and the product is fished out, washed, and dried to obtain modified cotton fiber.

3. The medical and sanitary nonwoven fabric according to claim 2, characterized in that: In step (1), the concentration of the sodium hydroxide aqueous solution is 10-20wt%, and the concentration of the potassium periodate aqueous solution is 5-10wt%; the amount ratio of the cotton fiber, the sodium hydroxide aqueous solution, and the potassium periodate aqueous solution is 10g:150-250mL:100-200mL.

4. The medical and sanitary nonwoven fabric according to claim 2, characterized in that: In step (1), the stirring reaction conditions are 30-60° C. and 0.5-2 h; the light-shielding reaction conditions are 25-55° C. and 200-300 r / min in the dark and stirring reaction for 2-8 h; the product is washed 3-5 times with deionized water, then washed once with ethanol, and dried at 40-60° C. for 3-6 h.

5. The medical and sanitary nonwoven fabric according to claim 2, characterized in that: In step (2), the usage ratio of polyethyleneimine-cyclodextrin and deionized water is 3-7 g:80-150 mL, the usage ratio of wormwood essential oil and ethanol is 0.5-2 g:15-30 mL; the usage ratio of polyethyleneimine-cyclodextrin and wormwood essential oil is 3-8:

1.

6. The medical and sanitary nonwoven fabric according to claim 2, characterized in that: In step (2), the wormwood essential oil alcohol solution is slowly added dropwise to the polyethyleneimine-cyclodextrin aqueous solution at a speed of 0.5 to 2 mL / min, and ultrasonic treatment is performed for 5 to 10 minutes every 10 to 20 minutes; the reflux reaction conditions are stirring and reflux reaction at 35 to 50° C. for 3 to 6 hours; the product is subjected to reduced pressure rotary evaporation to remove ethanol, and then freeze-dried for 12 to 24 hours.

7. The medical and sanitary nonwoven fabric according to claim 2, characterized in that: In step (3), the concentration of the acetic acid aqueous solution is 1-2 wt %, and the amount ratio of chitosan, acetic acid aqueous solution, aldehyde-modified cotton fiber, and wormwood essential oil inclusion complex is 1.5-4.5 g: 80-150 mL: 10 g: 2-5 g.

8. The medical and sanitary nonwoven fabric according to claim 2, characterized in that: In step (3), the stirring and dissolving conditions are: stirring at 45-60° C. until completely dissolved to obtain a transparent viscous solution; the stirring and dispersion conditions are: stirring at 40-55° C. and 150-300 r / min for 0.5-2 h; the stirring reaction conditions are: stirring at 40-55° C. and 150-300 r / min for 4-10 h; the product is washed with deionized water 3-5 times, then washed once with ethanol, and vacuum dried at 40-60° C. for 6-12 h.

9. The medical and sanitary nonwoven fabric according to claim 1, characterized in that: The non-woven fabric has a gram weight of 50 to 120 g / m 2 .

10. A method for preparing a nonwoven fabric for medical use according to any one of claims 1 to 9, characterized in that: The method comprises the following steps: mixing polylactic acid fibers and modified cotton fibers and combing them to form a fiber web, and then hydroentangling and reinforcing the fiber web.

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