Real-time monitoring equipment and monitoring method for peritoneal drainage liquid hemoglobin

Abstract

The invention provides peritoneal drainage liquid hemoglobin real-time monitoring equipment and a monitoring method.The monitoring equipment comprises a sensing bottle, the liquid inlet end of the sensing bottle is connected with a liquid inlet connecting pipe, the liquid outlet end of the sensing bottle is connected with a liquid outlet connecting pipe, the liquid inlet connecting pipe is communicated with the output end of a peritoneal drainage pipe, and the liquid outlet connecting pipe is communicated with the input end of drainage equipment; the sensing bottle comprises a side plate A extending in the Z direction, and a pair of electrodes and a temperature sensor are arranged on the inner wall face of the side plate A; and the control box is connected with the outer wall surface of the sensing bottle, is connected with the temperature sensor, and outputs sine wave voltage signals of 100KHz and 500KHz to the pair of electrodes, and the two voltage signals appear alternately. According to the method, the three defects of unclear seeing, inaccurate measurement and slow response of a traditional method are overcome, and a standardized and quantitative early warning scheme is provided for postoperative bleeding.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical monitoring, and in particular relates to a real-time monitoring device and method for hemoglobin in peritoneal drainage fluid. Background Art

[0002] Drainage management after abdominal surgery is a key part of postoperative monitoring, and its importance is mainly reflected in the following aspects: First, drainage tube placement is crucial for postoperative recovery. Following abdominal surgery such as liver resection, pancreaticoduodenectomy, or gastrointestinal surgery, drainage plays multiple roles: not only is it an important window for monitoring postoperative bleeding, but it also effectively drains inflammatory exudates from the peritoneal cavity, reducing the risk of infection. More importantly, drainage tube placement allows for early detection of serious complications such as anastomotic leaks, lymphatic leaks, pancreatic juice leaks, or bile leaks, buying valuable time for clinical intervention.

[0003] However, there are significant flaws in the monitoring of drainage fluid in current clinical practice. Traditional methods mainly rely on the naked eye observation and experience judgment of medical staff, which has obvious limitations. On the one hand, the sensitivity of naked eye observation is limited. Studies have shown that when the hemoglobin content in the drainage fluid is less than 5%, the color change is often difficult to detect, resulting in missed diagnosis of early bleeding. On the other hand, this method lacks real-time performance. Medical staff usually record the drainage volume every 4-6 hours, making it difficult to detect sudden bleeding in a timely manner.

[0004] The existing monitoring methods still have the following problems: Highly subjective: Different medical staff may have different judgments on the color of drainage fluid; Difficulty in differentiation: It is impossible to accurately distinguish between bleeding and bile or exudate; Delayed response: abnormalities can often be detected only after drainage volume increases significantly or the patient develops clinical symptoms; There are many interfering factors: blood clots and drug residues in the drainage fluid will affect the accuracy of the judgment.

[0005] These deficiencies often lead to two adverse clinical outcomes: either overreaction, misinterpreting normal exudate as bleeding, or delayed diagnosis, resulting in hemodynamic instability in the patient by the time significant bleeding is detected. Studies have shown that nearly 30% of post-hepatectomy bleeding cases are delayed due to untimely drainage fluid monitoring. Summary of the Invention

[0006] The purpose of the present invention is to provide a real-time monitoring device and method for hemoglobin in peritoneal drainage fluid, which solves the above-mentioned technical problems. The technical solution adopted is: A real-time monitoring device for hemoglobin in peritoneal drainage fluid, comprising: The sensing bottle 3 has a liquid inlet end connected to the liquid inlet pipe 1 and a liquid outlet end connected to the liquid outlet pipe 8. The liquid inlet pipe 1 is connected to the output end of the abdominal drainage tube, and the liquid outlet pipe 8 is connected to the input end of the drainage device. The sensing bottle 3 includes a side plate A extending along the Z direction, and a pair of electrodes 6 and a temperature sensor 7 are provided on the inner wall surface of the side plate A; And the control box 12 is connected to the outer wall of the sensing bottle 3, which is connected to the temperature sensor 7, which outputs 100KHz and 500KHz sinusoidal wave voltage signals to a pair of electrodes 6, and the two voltage signals appear alternately.

[0007] Preferably, it further includes a guide 2, which is located in the sensing bottle 3 and connected to the liquid inlet pipe 1, and is arranged obliquely, and a liquid sensing area 5 is formed between its outlet and a pair of electrodes 6 and a temperature sensor 7; The highest point of the outlet of the guide 2 is higher than the electrode 6 .

[0008] Preferably, it further includes a pair of liquid guardrails 15, wherein a liquid guardrail 15 is provided on both sides of the liquid sensing area 5 along the Y direction; the liquid guardrail 15 is arranged on the inner wall surface of the side plate A; and along the X direction, the liquid guardrail 15 is higher than the electrode 6.

[0009] Preferably, the control box 12 includes: The box body, the circuit-control module 4 and the battery 13 arranged in the box body; the box body is connected to the outer wall surface of the sensing bottle 3; The circuit-control module 4 includes a functional circuit and an MCU; The temperature processing unit of the functional circuit is connected to the temperature sensor 7, the signal output unit of the functional circuit is connected to a pair of electrodes 6, the output indication unit of the functional circuit is connected to five status indicator lights 10, and the communication unit of the functional circuit is connected to the MCU; the power ports of the functional circuit and the MCU are connected to the battery 13; The signal output unit of the functional circuit outputs 100KHz and 500KHz sinusoidal wave voltage signals, and the two voltage signals appear alternately; and a PCB board 11, which is disposed in the box body and on which are provided electrode sheets, the battery 13 and the circuit-control module 4; The electrode sheet is an elastic conductor, one end of which is connected to the PCB board 11 and the other end of which is in contact with an electrode of the battery 13 during normal operation.

[0010] Preferably, the box further comprises a battery separator 14, one end of which is placed between the battery 13 and the electrode sheet, and the other end of which extends outward from the box body.

[0011] A method for monitoring the hemoglobin content in peritoneal drainage fluid, based on the real-time hemoglobin monitoring device for peritoneal drainage fluid, comprises the following steps: Step 1: Establish a hemoglobin content calculation model ; The hemoglobin content calculation model is a model about an impedance term, wherein the impedance term includes: Impedance dynamic model , the impedance amplitude of the drainage fluid under the 100KHz detection signal , imaginary impedance of hemoglobin Hb under 500KHz detection signal , the imaginary impedance of the drainage fluid under 500KHz detection signal ; in, This is the empirical value of the normal human body temperature of 37°C; -impedance; -time; - Hemoglobin; - drainage fluid; Step 2: Solve the impedance dynamic model , and bring in ; Step 3: Create a 、 Supplementary temperature compensation model; Step 4: Connect the real-time monitoring device for hemoglobin in the peritoneal drainage fluid between the peritoneal drainage tube and the drainage device. At this time, the postoperative time t=0; The MCU records the postoperative time t in real time; the temperature sensor monitors the drainage fluid temperature signal T in real time and transmits it to the MCU through the temperature processing unit and communication unit of the functional circuit; Step 5: Calculate 、 ; Step 6: Apply the temperature compensation model to 、 make compensation; Step 7: After compensation Enter the bile interference detection model to determine whether there is bile interference in the drainage fluid; if not, proceed to step 8; Step 8: Based on the postoperative time t, the drainage fluid temperature T corresponding to the postoperative time t, and the compensated value obtained in step 6 、 , and obtained in step 2 , obtain the hemoglobin content.

[0012] Preferably, the hemoglobin content calculation model in step 1 is for: ; Impedance dynamic model in step 2 for: .

[0013] Preferably, the temperature compensation model in step 3 is: ; in, -compensate.

[0014] Preferably, the bile interference detection model in step 7 is: ; = After compensation .

[0015] Preferably, if bile interference is determined in step 7, the corresponding indicator light responds, followed by manual confirmation; If it is determined that there is no bile interference, based on the hemoglobin content value obtained in step 8, the risk level is corresponding to the set value of the program, and the corresponding indicator light and clinical response are activated according to the risk level.

[0016] Compared with the existing technology, the advantages of the present invention are: cavity drainage is the "lifeline" of postoperative management, and this application uses impedance method φHb monitoring, that is, hemoglobin monitoring, to solve the three major defects of traditional methods: "unclear, inaccurate measurement, and slow response", and provides a standardized and quantitative early warning solution for postoperative bleeding. Specifically: (1) Through innovative impedance detection technology, the system can monitor the hemoglobin content in the drainage fluid in real time and quantitatively, with a sensitivity of up to 2%, which is much higher than the 5% threshold of naked eye observation.

[0017] (2) The addition of the temperature compensation algorithm ensures the accuracy of the measurement results, while the five-level alarm system provides a clear basis for clinical decision-making.

[0018] (3) Compared with traditional methods, this system advances the average time of bleeding detection by 2-4 hours, thus gaining a valuable time window for clinical intervention.

[0019] (4) In addition, the system's unique bile interference recognition function solves the common clinical false alarm problem. When bile mixing characteristics are detected, the system will activate a special prompt, avoiding unnecessary alarms and reminding medical staff to pay attention to possible bile leakage complications. This intelligent discrimination capability is completely unattainable by traditional naked eye observation. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1This is a schematic diagram of the clinical application of the real-time monitoring device for hemoglobin in peritoneal drainage fluid; Figure 2 A comparison diagram of the cross-sectional view and top view of the real-time monitoring device for hemoglobin in peritoneal drainage fluid; Figure 3 for Figure 2 A partial view of Figure 4 Schematic diagram of the installation method of the real-time monitoring device for hemoglobin in peritoneal drainage fluid in one embodiment.

[0021] Among them, 1-liquid inlet pipe, 2-guide, 3-sensing bottle, 4-circuit-control module, 5-liquid sensing area, 6-electrode, 7-temperature sensor, 8-liquid outlet pipe, 9-reset switch, 10-indicator light, 11-PCB board, 12-control box, 13-battery, 14-battery isolation sheet, 15-liquid guardrail. DETAILED DESCRIPTION

[0022] The following is a more detailed description of the real-time peritoneal drainage fluid hemoglobin monitoring device and monitoring method of the present invention, with reference to schematic diagrams. These diagrams illustrate preferred embodiments of the present invention. It should be understood that those skilled in the art may modify the present invention described herein while still achieving the beneficial effects of the present invention. Therefore, the following description should be understood as generally known to those skilled in the art and is not intended to limit the present invention.

[0023] like Figures 1-3 , a real-time monitoring device for hemoglobin in peritoneal drainage fluid, suitable for early warning of bleeding risk after abdominal surgery, including: The sensing bottle 3 has a liquid inlet end connected to a liquid inlet pipe 1 and a liquid outlet end connected to a liquid outlet pipe 8. The liquid inlet pipe 1 is connected to the output end of the peritoneal drainage tube, and the liquid outlet pipe 8 is connected to the input end of the drainage device. The sensing bottle 3 includes a side plate A extending along the Z direction. A pair of electrodes 6 and a temperature sensor 7 are adhered to the inner wall surface of the side plate A using epoxy resin. In this embodiment, the liquid inlet pipe 1 is sealed and bonded to the sensing bottle 3 , and the liquid outlet pipe 8 is sealed and bonded to the sensing bottle 3 .

[0024] and a control box 12, which includes a box body, a circuit-control module 4 disposed in the box body, and a battery 13; The box body is connected to the outer wall surface of the sensing bottle 3. In this embodiment, the control box 12 and the sensing bottle 3 share a side plate A.

[0025] The circuit-control module 4 includes a functional circuit and an MCU.

[0026] The temperature processing unit of the functional circuit is connected to the temperature sensor 7, the signal output unit of the functional circuit is connected to a pair of electrodes 6, the output indication unit of the functional circuit is connected to five status indicator lights 10, and the communication unit of the functional circuit is connected to the MCU; the power ports of the functional circuit and the MCU are connected to the battery 13; The signal output unit of the functional circuit outputs 100KHz and 500KHz sinusoidal wave voltage signals, and the two voltage signals appear alternately.

[0027] That is, the temperature sensor 7 transmits the drainage fluid temperature signal T to the MCU through the temperature processing unit and the communication unit of the functional circuit; The battery 13 supplies power to the MCU and the functional circuit. Under the control of the MCU, the signal output unit of the functional circuit alternately outputs 100KHz and 500KHz sinusoidal wave voltage signals.

[0028] In this embodiment, a guide 2 is further provided, which is located in the sensing bottle 3 and connected to the liquid inlet pipe 1.

[0029] The inlet liquid channel of the guide 2 is connected to the liquid inlet pipe 1 , and the guide 2 and the liquid inlet pipe 1 are integrally formed.

[0030] The guide 2 is tilted, and a liquid sensing area 5 is formed between its outlet and a pair of electrodes 6 and a temperature sensor 7 ; the highest point of the outlet of the guide 2 is higher than the electrodes 6 .

[0031] In this embodiment, a pair of liquid barriers 15 are further provided. Along the Y-axis, one liquid barrier 15 is provided on each side of the liquid sensing area 5. The liquid barriers 15 are provided on the inner wall of the side panel A. Along the X-axis, the liquid barriers 15 are higher than the electrodes 6. Specifically, the liquid barriers 15 and the side panel A are integrally molded.

[0032] Regarding, the control box 12 further comprises: The PCB board 11 is installed in the box body, and is provided with electrode sheets, batteries 13 and circuit-control module 4.

[0033] Specifically, the two electrode sheets (electrode sheet B and electrode sheet C) of the battery 13 are both soldered to the PCB board; The battery 13 is fixed to the battery plastic holder on the PCB board through a heat riveting process, and conducts electricity through two electrode sheets to supply power to the MCU and functional circuits.

[0034] The circuit-control module 4 is embedded in the PCB board.

[0035] The electrode sheet is an elastic conductor, one end of which is connected to the PCB board 11, and the other end of which is in contact with an electrode of the battery 13 during normal operation. When not in operation, a battery separator is placed between the battery and the electrode sheet.

[0036] One end of the battery separator 14 is placed between the battery 13 and the electrode sheet (electrode sheet B), and the other end thereof extends out of the box body.

[0037] This device is connected in series to the drainage tube between the patient's abdominal drainage tube and the drainage device. The drainage device can be a container for passive drainage or a negative pressure suction device for active drainage, such as Figure 1 shown.

[0038] Specifically, regarding the real-time monitoring device for hemoglobin in peritoneal drainage fluid: Liquid inlet pipe 1: located above the sensing bottle 3, connected to the patient end of the peritoneal drainage tube, the inner diameter of the pipe is greater than 8mm; Guide 2: Its upper end is connected to the liquid inlet 1, and the lower end opening is close to the electrode 6 and the temperature sensor 7. The upper part of the guide outlet is 4-6 mm higher than the electrode to ensure that the patient's drainage fluid can effectively flow through the electrode and the temperature sensor, especially when the drainage volume is small; Sensing bottle 3: It is a sealed container, with the upper end connected to the liquid inlet pipe 1 and the lower end connected to the liquid outlet pipe 8. A pair of gold-plated electrodes and a temperature sensor 7 are installed on the right side of the container. The volume of the entire sensing bottle is greater than 100ml and the height is greater than 80mm. Conditioning circuit and MCU (circuit-control module 4): Installed on the PCB in the controller box 12, it consists of functional circuits and MCU and is used for waveform generation, constant current control, complex impedance extraction, output display, audio control, and related mathematical operations and logical judgments; Liquid sensing area 5: This area is the narrow gap between the outlet of the guide 2 and the electrode 6 and temperature sensor 7. The width of the narrow gap is 2-3mm, so that the outflowing liquid can effectively contact the electrode and temperature sensor, especially when the drainage volume is small; Electrode 6: It is a pair of electrolytic copper gold-plated electrodes, with a single effective size of not less than 6X8mm. A temperature sensor is installed in the middle of the electrode. The electrode is installed on the common isolation device between the sensing bottle and the controller box (a common "wall"). When working, the waveform generating circuit generates an open-circuit voltage of 5V and a constant current of 100 microamperes. The electric signal is applied to this electrode pair, and the frequencies are 100KHz and 500KHz, alternating at intervals of 800ms.

[0039] Temperature sensor 7: This sensor is a small platinum temperature sensor with an effective temperature sensing area of ​​less than 4mm 2 , so that it has the smallest possible heat capacity, thereby achieving a rapid temperature response; Liquid outlet pipe 8: located at the bottom of the sensing bottle, the inner diameter of the pipe is greater than 8mm, and is used to connect the catheter of the drainage device; reset switch 9: used to manually eliminate the sound prompt or unexpected LED error display.

[0040] Indicator 10: There are 5 LEDs from top to bottom, namely green, yellow, orange, red and blue, representing normal, mild bleeding, active bleeding, critical bleeding and bile interference respectively. The five indicators are "five-choice one", that is, only one is lit at a time; PCB board 11: circuit board in the control box; Control box 12: Contains a battery, signal processing circuit, MCU, switch, buzzer, and five LED indicators. The control box and the sensor bottle share an isolation device (a shared "wall"). Electrodes and a temperature sensor are installed on the sensor bottle side of the "wall." The leads between the temperature sensor and the electrodes are sealed to effectively prevent leakage of patient drainage fluid from the sensor bottle into the control box. Battery 13: This device is sterilized with ethylene oxide and is disposable. It is factory-installed with a 3.3V non-replaceable battery that can keep the device working for more than 48 hours. Battery separator 14: A 0.5-1mm thick polymer insulating soft material gasket that acts as a switch, isolating one electrode of the battery from the circuit. When in use, remove this separator to connect the power supply. The battery separator cannot be put back after being removed, ensuring that the device is disposable and preventing battery consumption when not in use. Liquid guardrail 15: This guardrail cooperates with the guide to ensure that the liquid drained from the patient's abdominal cavity can reliably flow through the electrode sheet and temperature sensor. The effective height of the guardrail, that is, the distance between the protrusion and the electrode surface, is 3-6mm, and the upper end of the guardrail is flush with the upper end of the upper electrode sheet. Figure 2 Due to viewing angle reasons, the liquid guardrail 15 is not shown in the cross-sectional view.

[0041] Furthermore, in other embodiments, the real-time monitoring device for hemoglobin in peritoneal drainage fluid can be as follows: Figure 4 Designed and installed as shown. Figure 4 Only one electrode pad is shown.

[0042] A method for monitoring hemoglobin content in peritoneal drainage fluid comprises the following steps: Step 1: Establish a hemoglobin content calculation model ; Hemoglobin content calculation model is a model about impedance terms, which includes: Impedance dynamic model , the impedance amplitude of the drainage fluid under the 100KHz detection signal , imaginary impedance of hemoglobin Hb under 500KHz detection signal , the imaginary impedance of the drainage fluid under 500KHz detection signal ; in, This is the empirical value of the normal human body temperature of 37°C; -impedance; -time; - Hemoglobin; - drainage fluid; Hemoglobin content calculation model for: ; Table 1 Parameter definition table symbol Physical meaning 37℃ calibration value Data Source Dynamic baseline Starting point value 62 Ending point value 58 Empirical values ​​are considered as two constants and extracted based on the rules of big data Impedance amplitude of the mixed liquid under 100KHz detection signal Compensation required Actual measured impedance amplitude The imaginary impedance of hemoglobin Hb under 500KHz detection signal -20.5±1.5 The empirical value is regarded as a constant and is extracted based on the rules of big data. Imaginary impedance of the mixed liquid under 500KHz detection signal Compensation required The actual measured imaginary part of the impedance T Real-time temperature of drainage fluid Compensate with this temperature Actual measured In this embodiment, "mixed liquid" refers to the flow liquid.

[0043] Step 2: Solve the impedance dynamic model , and bring in .

[0044] The hemoglobin in the patient's peritoneal drainage fluid after surgery will gradually decrease as the patient recovers, so this baseline cannot be a constant, but a dynamic baseline model.

[0045] The dynamic baseline model is essentially a time-varying plasma baseline model , this model is a function of time, its initial baseline impedance is the value at T=0, and its attenuation end baseline impedance is the value at T→∞, To establish a dynamic baseline model (impedance dynamic model), it is first necessary to determine the impedance values ​​at the initial point and the end point of the decay.

[0046] Initial impedance value: Based on the actual postoperative bleeding situation of abdominal cavity as the big data source, an 80 / 20 standard was extracted, which defaults to 80% plasma components and 20% blood components.

[0047] 80% of the plasma component corresponds to the tissue fluid exuded from the wound surface in the early postoperative period, and its impedance characteristics are consistent with those of healthy plasma ( =55Ω), its physiological origin is surgical trauma leading to increased vascular permeability and leakage of plasma proteins and electrolytes.

[0048] 20% of the blood components correspond to the residual or early extravasated whole blood during the operation, and the impedance is dominated by the red blood cell membrane capacitance ( =90Ω, 40% HCT). The physiological source is that intraoperative microvascular damage cannot be completely avoided.

[0049] The weighted formula for the derivation of the initial value of the 80 / 20 mixture model is: ; mix-minimum value; -initial.

[0050] Simplified linear approximation (error < 3%): ; Attenuation endpoint impedance value: theoretically, the drainage fluid composition approaches the pure plasma state, that is, 100% plasma composition, which is set as the standard impedance amplitude of pure plasma at 100kHz at 37°C, T→∞, Lim =58Ω.

[0051] Dynamic baseline time function: The initial value is 62Ω. As the patient gradually recovers, this baseline value will tend to 58Ω in the pure plasma state.

[0052] We found from big data experiments that this function is a piecewise function: Impedance Dynamic Model : ; Table 2 Clinical basis for dynamic adjustment Postoperative time Adjustment strategy Physiological mechanisms 0-6 hours Fixed 62Ω In the exudative stage of trauma, the bleeding ratio is stable 6-24 hours Linearly adjust down to 58Ω Tissue repair reduces bleeding, and the proportion of plasma increases >24 hours Fixed 58Ω (pure plasma reference) When there is no active bleeding, the drainage fluid tends to be plasma Step 3: Create a 、 A supplementary temperature compensation model is performed.

[0053] because -20.5±1.5Ω is the empirical average value of large amounts of data under 37°C patient body fluids. Therefore, in actual calculations, compensation correction must be made according to the actual temperature of the patient's drainage fluid, correcting it to the corresponding value under 37°C conditions. Because the patient's body temperature will rise slightly after surgery, the drainage fluid of clinical patients is usually greater than 37°C. The compensation formula, that is, the temperature compensation model, is as follows: Temperature compensation model: ; in, -compensate.

[0054] Step 4: Connect the real-time monitoring device for hemoglobin in the peritoneal drainage fluid between the peritoneal drainage tube and the drainage device. At this time, the postoperative time t=0; The MCU records the postoperative time t in real time; the temperature sensor monitors the drainage fluid temperature signal T in real time and uploads it to the MCU through the temperature processing unit and communication unit of the functional circuit; Step 5: MCU calculates 、 .

[0055] Among them, step 5 belongs to the existing technology.

[0056] Step 6: Apply the temperature compensation model to 、 Perform compensation to obtain the temperature compensated value and .

[0057] Step 7: After compensation Enter the bile interference detection model to determine whether there is bile interference in the drainage fluid; if not, proceed to step 8.

[0058] Patients undergoing abdominal surgery, especially hepatobiliary surgery, often have bile mixed in the drainage mixture. Bile interferes with hemoglobin detection. This system has a bile marker prompt function.

[0059] Bile interference detection model, that is, the condition for the bile flag to be true is: ; = After compensation

[0060] If bile interference is determined, the corresponding indicator light responds, and the drainage fluid situation is then manually confirmed.

[0061] Step 8: Based on the postoperative time t, the drainage fluid temperature T corresponding to the postoperative time t, and the compensated value obtained in step 6 、 , and obtained in step 2 , obtain the hemoglobin content.

[0062] Step 9. Press Values ​​<2%, 2-5%, 5-8%, and >8% are divided into four levels, corresponding to the four risk levels of normal, mild bleeding, active bleeding, and critical bleeding.

[0063] Table 3 Risk thresholds Risk Level Threshold Clinical response normal ＜2% Routine monitoring Mild bleeding 2-5% Ultrasound review Active bleeding 5-8% Emergency CT Critical bleeding ＞8% Surgical preparation Bile interference Imaginary part ratio < 0.7 Manual confirmation Table 4 Five status indicators and sound prompt system Risk Level Threshold Indicator status Sound prompt status normal ＜2% Green light is always on No sound Mild bleeding 2-5% Yellow light constant Intermittent sound (1 second on, 1 second off) Active bleeding 5-8% Orange light flashes (0.4s on, 0.4s off) Intermittent sound and light flash synchronization Critical bleeding ＞8% Red light is on Long sound Bile interference Imaginary part ratio < 0.7 Blue light flashes slowly (0.8s on, 0.8s off) Intermittent sound (1s on, 2s off) Case 1: Post-pancreaticoduodenectomy (1) Data 18 hours after surgery Measurements: Impedance amplitude ; Imaginary impedance ; Temperature T = 38.1°C (2) Calculation steps Temperature compensation: ; ; Dynamic baseline (18 hours after surgery): ; Bile testing: ; Condition not met Hemoglobin calculation: ; determination: 2%<3.3%<5%→The yellow light is always on (mild bleeding).

[0064] Case 2: After liver resection (1) Data 24 hours after surgery Measurements: ; ; T=36.4℃ (2) Calculation steps Temperature compensation (when the temperature is close to 37°C, compensation can be ignored) , ; Bile testing: ; Since bile interference is confirmed, there is no need to calculate hemoglobin. determination: The system determines that it is bile interference → the blue light flashes slowly Case 3: Post-gastrectomy (1) Data 8 hours after surgery Measurements: ; ; T=37.8℃ (2) Calculation steps Temperature compensation: ; ; Dynamic baseline (8 hours after surgery): ; Bile testing: ; Hemoglobin calculation: ; determination: 11.2%>8%→Red light flashing rapidly (critical bleeding) The above description is merely a preferred embodiment of the present invention and does not limit the present invention in any way. Any person skilled in the art who, without departing from the scope of the present invention, makes any equivalent substitution, modification, or other changes to the technical solution and technical content disclosed in the present invention shall be deemed to be within the scope of the present invention and still fall within the scope of protection of the present invention.

Claims

1. A real-time monitoring device for hemoglobin in peritoneal drainage fluid, characterized in that: include: A sensing bottle (3), wherein the liquid inlet end is connected to the liquid inlet pipe (1), and the liquid outlet end is connected to the liquid outlet pipe (8), wherein the liquid inlet pipe (1) is connected to the output end of the peritoneal drainage tube, and the liquid outlet pipe (8) is connected to the input end of the drainage device, and the sensing bottle (3) comprises a side plate A extending in the Z direction, and a pair of electrodes (6) and a temperature sensor (7) are provided on the inner wall surface of the side plate A; And a control box (12) is connected to the outer wall of the sensing bottle (3), which is connected to the temperature sensor (7), and outputs 100KHz and 500KHz sinusoidal voltage signals to a pair of electrodes (6), and the two voltage signals appear alternately.

2. The real-time monitoring device for hemoglobin in peritoneal drainage fluid according to claim 1, characterized in that: It further comprises a guide (2), which is located in the sensing bottle (3) and connected to the liquid inlet pipe (1), and is arranged at an angle, and a liquid sensing area (5) is formed between its outlet and a pair of electrodes (6) and a temperature sensor (7); The highest point of the outlet of the guide (2) is higher than the electrode (6).

3. The real-time monitoring device for hemoglobin in peritoneal drainage fluid according to claim 2, characterized in that: It further comprises a pair of liquid guardrails (15), wherein a liquid guardrail (15) is provided on both sides of the liquid sensing area (5) along the Y direction; the liquid guardrails (15) are arranged on the inner wall surface of the side plate A; and along the X direction, the liquid guardrails (15) are higher than the electrodes (6).

4. The real-time monitoring device for hemoglobin in peritoneal drainage fluid according to claim 1, characterized in that: The control box (12) comprises: A box body, a circuit-control module (4) and a battery (13) arranged in the box body; the box body is connected to the outer wall surface of the sensing bottle (3); The circuit-control module (4) includes a functional circuit and an MCU; The temperature processing unit of the functional circuit is connected to a temperature sensor (7), the signal output unit of the functional circuit is connected to a pair of electrodes (6), the output indication unit of the functional circuit is connected to five status indicator lights (10), and the communication unit of the functional circuit is connected to the MCU; the power ports of the functional circuit and the MCU are connected to a battery (13); The signal output unit of the functional circuit outputs 100KHz and 500KHz sinusoidal wave voltage signals, and the two voltage signals appear alternately; and a PCB board (11), which is arranged in the box body and on which are provided electrode sheets, the battery (13) and the circuit-control module (4); The electrode sheet is an elastic conductor, one end of which is connected to the PCB board (11), and the other end of which is in contact with an electrode of the battery (13) during normal operation.

5. The real-time monitoring device for hemoglobin in peritoneal drainage fluid according to claim 4, characterized in that: It further comprises a battery isolation sheet (14), one end of which is placed between the battery (13) and the electrode sheet, and the other end of which extends outward from the box body.

6. A method for monitoring the hemoglobin content of peritoneal drainage fluid, based on the real-time hemoglobin monitoring device for peritoneal drainage fluid according to any one of claims 1 to 5, characterized in that: The following steps are involved: Step 1: Establish a hemoglobin content calculation model ; The hemoglobin content calculation model is a model about an impedance term, wherein the impedance term includes: Impedance dynamic model , the impedance amplitude of the drainage fluid under the 100KHz detection signal , imaginary impedance of hemoglobin Hb under 500KHz detection signal , the imaginary impedance of the drainage fluid under 500KHz detection signal ; in, This is the empirical value of the normal human body temperature of 37°C; -impedance; -time; - Hemoglobin; - drainage fluid; Step 2: Solve the impedance dynamic model , and bring in ; Step 3: Create a 、 Supplementary temperature compensation model; Step 4: Connect the real-time monitoring device for hemoglobin in the peritoneal drainage fluid between the peritoneal drainage tube and the drainage device. At this time, the postoperative time t=0; The MCU records the postoperative time t in real time; the temperature sensor monitors the drainage fluid temperature in real time and transmits the drainage fluid temperature signal T to the control box (12); Step 5: Calculate 、 ; Step 6: Apply the temperature compensation model to 、 make compensation; Step 7: After compensation Enter the bile interference detection model to determine whether there is bile interference in the drainage fluid; if not, proceed to step 8; Step 8: Based on the postoperative time t, the drainage fluid temperature T corresponding to the postoperative time t, and the compensated value obtained in step 6 、 , and obtained in step 2 , obtain the hemoglobin content.

7. The method for monitoring hemoglobin content in peritoneal drainage fluid according to claim 6, characterized in that: Hemoglobin content calculation model in step 1 for: ； Impedance dynamic model in step 2 for: 。 8. The method for monitoring hemoglobin content in peritoneal drainage fluid according to claim 6, characterized in that: The temperature compensation model in step 3 is: ； in, -compensate.

9. The method for monitoring hemoglobin content in peritoneal drainage fluid according to claim 6, characterized in that: The bile interference detection model in step 7 is: ； = After compensation .

10. The method for monitoring hemoglobin content in peritoneal drainage fluid according to claim 6, characterized in that: If bile interference is determined in step 7, the corresponding indicator light responds, and then manual confirmation is required; If it is determined that there is no bile interference, based on the hemoglobin content value obtained in step 8, the risk level is corresponding to the set value of the program, and the corresponding indicator light and clinical response are activated according to the risk level.

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