Antibody filling machine

Abstract

The invention discloses an antibody filling machine, and relates to the technical field of filling devices. Comprising a rack; the filling machine body is arranged on the rack; the adjusting box assembly is arranged on a liquid outlet pipe of the filling machine body; the filling head assembly is movably arranged on the bottom surface of the adjusting box assembly; the filling bottle placing assembly is movably arranged below the filling head assembly; the adjusting box assembly comprises an adjusting box communicated with a liquid outlet pipe of the filling machine body, the bottom face of the adjusting box is in an opening shape, and an elastic partition plate is arranged in each grid of the grid structure plate. The filling head assembly comprises a plurality of liquid outlet cylinders in one-to-one correspondence with the elastic partition plates, the liquid outlet cylinders are perpendicularly arranged on the elastic partition plates at the corresponding positions in a penetrating mode, the upper ends of the liquid outlet cylinders are open, and filling pipes are arranged in the lower ends of the liquid outlet cylinders. The filling device has the advantages that the filling efficiency is improved, and the leakage phenomenon is avoided during filling.

Description

Technical Field

[0001] The present invention relates to the technical field of filling devices, and in particular to an antibody filling machine. Background Art

[0002] Some existing antibody filling devices use only one filling tube during the filling operation, and cannot fill multiple containers at the same time according to different needs, resulting in low filling efficiency. At the same time, it is inconvenient to fix the container containing the antibody reagent during filling, which makes it easy for the antibody reagent to leak during filling, causing waste and pollution. Summary of the Invention

[0003] In view of the above-mentioned technical deficiencies, the object of the present invention is to provide an antibody filling machine, which has the advantages of improving filling efficiency and avoiding leakage during filling.

[0004] In order to solve the above technical problems, the present invention adopts the following technical solution: The present invention provides an antibody filling machine, comprising: frame; Filling machine body, the filling machine body is arranged on the frame; The regulating box assembly is arranged on the liquid outlet pipe of the filling machine body; A filling head assembly, the filling head assembly is movably arranged on the bottom surface of the regulating box assembly; A filling bottle placing component is movably arranged below the filling head component; The regulating box assembly includes a regulating box connected to the liquid outlet pipe of the filling machine body, the bottom surface of the regulating box is open, and a grid structure plate is horizontally arranged in the opening of the bottom surface of the regulating box, and an elastic partition is arranged in each grid of the grid structure plate; The filling head assembly includes a plurality of liquid discharge cylinders corresponding to the elastic partitions one by one. The liquid discharge cylinders are respectively vertically penetrated on the elastic partitions arranged at corresponding positions. The upper end of the liquid discharge cylinder is open, and the lower end of the liquid discharge cylinder is provided with a filling tube. The filling bottle placement assembly includes a grid placement plate movably arranged under the liquid discharge cylinder, the position of the grid on the grid placement plate corresponds one to one with the position of the grid on the grid structure plate, and the adjusting cylinders on opposite sides of the top of the frame, and the opposite ends of the grid placement plate are respectively connected to the piston rods of the two adjusting cylinders.

[0005] Preferably, the distance from the outlet of the liquid outlet pipe of the filling machine body to the top surface of the grid structure plate is smaller than the distance from the upper end of the liquid outlet cylinder to the top surface of the grid structure plate, so that the position of the liquid outlet cylinder can be adjusted as needed, thereby enabling the liquid outlet cylinder at the corresponding position to perform filling operations.

[0006] Preferably, a fixed plate is arranged between the grid structure plate and the grid placement plate, and a plurality of threaded holes corresponding to the liquid discharge cylinders are provided on the fixed plate. An external threaded sleeve is provided on the external rotating sleeve of the lower end of the liquid discharge cylinder, and the external threaded sleeve is threadedly connected in the threaded hole, so that the position of the liquid discharge cylinder in the upper and lower directions can be adjusted conveniently by rotating the external threaded sleeve in the threaded hole.

[0007] Preferably, a transparent observation window is provided on the top surface of the regulating box to facilitate observation of the capacity of the antibody reagent in the regulating box.

[0008] Preferably, a hollow hemispherical cover is movably provided at the lower end of the liquid discharge cylinder, and the filling tube is located in the arc-shaped opening of the hollow hemispherical cover. When filling is not required, the hollow hemispherical cover can be installed at the lower end of the liquid discharge cylinder, thereby protecting the filling tube.

[0009] Preferably, a plate rack is provided below the liquid discharge cylinder, and the plate rack comprises: Left rack; The right frame, the left frame and the right frame are arranged in parallel and spaced apart below the liquid discharge cylinder, and the grid placement plate is slidably arranged between the left frame and the right frame; There are two plate slots, one on the side wall of the left frame and the other on the side wall of the right frame, which makes it easy to adjust the position of the grid placement plate between the left frame and the right frame, which is beneficial to the filling operation.

[0010] Preferably, the cross-section of the plate slot is adapted to the cross-section of the grid placement plate, so that the grid placement plate can be removed from the plate slot after the filling operation is completed.

[0011] Preferably, sliders are provided at both opposite ends of the grid placement plate, and the two sliders correspond to the positions of the two adjusting cylinders respectively. An internal threaded hole is provided in the top surface of the slider, and a threaded rod is coaxially provided on the piston rod of the adjusting cylinder, and the threaded rods are respectively threadedly connected to the internal threaded holes at corresponding positions, so that before the filling operation, the grid placement plate can be moved toward the liquid discharge cylinder by adjusting the cylinder, thereby facilitating the filling operation; at the same time, when the filling operation is completed, the grid placement plate can be moved away from the liquid discharge cylinder by adjusting the cylinder, so that the grid placement plate can be removed from the plate slot position.

[0012] Preferably, a slider groove that matches the size of the slider is provided at the open top of the plate groove, and the slider is slidably arranged in the slider groove at the corresponding position, which is conducive to keeping the grid placement plate in a stable position when moving.

[0013] Preferably, guide rods are vertically provided at both opposite ends of the fixed plate, and the guide rods are movably extended through the opposite ends of the grid placement plate away from the fixed plate end, and the distance from the guide rods away from the fixed plate end to the bottom surface of the frame is greater than the distance from the plate groove to the bottom surface of the frame, which is conducive to ensuring that the grid placement plate is in a stable position when moving toward or away from the liquid discharge cylinder.

[0014] The beneficial effects of the present invention are as follows: 1. By setting up a grid placement plate, a corresponding number of containers containing antibody reagents can be placed in the grids of the grid placement plate according to filling needs, so that the grid placement plate can complete the filling operation at the same time, thereby improving the filling efficiency and filling convenience; at the same time, it is also convenient to fix the containers containing antibody reagents during the filling operation to avoid leakage of the antibody reagents.

[0015] 2. The grid placement plate can be moved up and down under the action of the regulating cylinder. On the one hand, it is beneficial to insert the filling tube into the opening of the container containing the antibody reagent at the corresponding position during filling, which can prevent leakage during filling; on the other hand, when the filling is completed, the regulating cylinder drives the grid placement plate to move away from the liquid discharge cylinder, which facilitates the removal of the grid placement plate and the container containing the antibody reagent in the grid placement plate from the plate slot. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0017] Figure 1 This is a structural schematic diagram of an antibody filling machine provided by an embodiment of the present invention.

[0018] Figure 2 for Figure 1 A magnified schematic diagram of the structure in the middle.

[0019] Figure 3 A schematic diagram of the position of a fixed plate of an antibody filling machine provided by an embodiment of the present invention.

[0020] Figure 4 A schematic diagram of the filling tube position of an antibody filling machine provided in an embodiment of the present invention.

[0021] Figure 5 A schematic diagram of the grid placement plate structure of an antibody filling machine provided by an embodiment of the present invention.

[0022] Figure 6A schematic diagram of the positions of threaded holes of an antibody filling machine provided by an embodiment of the present invention.

[0023] Figure 7 A schematic diagram of the grid structure plate structure of an antibody filling machine provided by an embodiment of the present invention.

[0024] Figure 8 A schematic diagram of the position of a slider slot of an antibody filling machine provided by an embodiment of the present invention.

[0025] Explanation of the accompanying drawings: 1. Frame; 2. Filling machine body; 3. Adjustment box assembly; 31. Adjustment box; 311. Transparent observation window; 32. Grid structure plate; 33. Elastic partition; 4. Filling head assembly; 41. Liquid discharge cylinder; 411. Hollow hemispherical cover; 42. Filling tube; 5. Filling bottle placement assembly; 51. Grid placement plate; 511. Slider; 512. Internal threaded hole; 513. Threaded rod; 52. Adjusting cylinder; 6. Fixed plate; 61. Threaded hole; 62. External threaded sleeve; 63. Guide rod; 7. Plate frame; 71. Left frame; 72. Right frame; 73. Plate slot; 731. Slider slot. DETAILED DESCRIPTION

[0026] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0027] Example 1 like Figures 1 to 5 、 Figure 7As shown, the present invention provides an antibody filling machine, comprising a frame 1; a filling machine body 2 is arranged on the frame 1; a regulating box assembly 3 is arranged on the liquid outlet pipe of the filling machine body 2; a filling head assembly 4 is movably arranged on the bottom surface of the regulating box assembly 3; a filling bottle placement assembly 5 is movably arranged below the filling head assembly 4; the regulating box assembly 3 includes a regulating box 31 connected to the liquid outlet pipe of the filling machine body 2, the bottom surface of the regulating box 31 is open, and a grid structure plate 32 is horizontally arranged in the opening of the bottom surface of the regulating box 31, and each grid of the grid structure plate 32 is provided with an elastic partition 33; the filling The head assembly 4 includes a plurality of liquid discharge cylinders 41 corresponding one to one with the elastic partitions 33. The liquid discharge cylinders 41 are respectively vertically penetrated through the elastic partitions 33 arranged at corresponding positions. The upper end of the liquid discharge cylinder 41 is open, and a filling tube 42 is arranged in the lower end of the liquid discharge cylinder 41; the filling bottle placement assembly 5 includes a grid placement plate 51 movably arranged below the liquid discharge cylinder 41. The position of the grid of the grid placement plate 51 corresponds one to one with the position of the grid of the grid structure plate 32. The adjusting cylinders 52 are on opposite sides of the top of the frame 1, and the opposite ends of the grid placement plate 51 are respectively connected to the piston rods of the two adjusting cylinders 52.

[0028] The antibody reagent in the filling machine body 2 can enter the regulating box 31 through the liquid outlet pipe on the filling machine body 2, and then, according to the filling needs, the upper and lower positions of the liquid discharge cylinder 41 are rotated and adjusted on the elastic partition 33 (the elastic partition 33 is provided to move accordingly with the upper and lower movements of the liquid discharge cylinder 41, and can ensure the sealing between the liquid discharge cylinder 41 and the grid of the grid structure plate 32 when the liquid discharge cylinder 41 moves up and down), so that the upper end opening of the liquid discharge cylinder 41 is higher or lower than the liquid level of the antibody reagent in the regulating box 31, so that the liquid discharge cylinder 41 in the corresponding position can be used for filling; before filling, according to the filling quantity required, a corresponding number of containers containing antibody reagents can be placed in each grid of the grid placement plate 51, and then the regulating cylinder 52 is started to drive the grid placement plate 51 to move in the direction close to the filling tube 42, so that the containers containing antibody reagents placed in the grids of the grid placement plate 51 can be respectively matched with the filling tube 42, thereby completing the filling operation.

[0029] The filling tube 42 may be provided with a control switch so that when the antibody reagent is being filled, the filling tube 42 that does not need to be filled can be closed.

[0030] Example 2 Based on the first embodiment, Figure 1 、 Figure 3 、 Figure 6As shown, the distance from the outlet of the liquid discharge pipe of the filling machine body 2 to the top surface of the grid structure plate 32 is smaller than the distance from the upper end of the liquid discharge cylinder 41 to the top surface of the grid structure plate 32; a fixed plate 6 is arranged between the grid structure plate 32 and the grid placement plate 51, and a plurality of threaded holes 61 corresponding to the liquid discharge cylinder 41 are provided on the fixed plate 6, and an external threaded sleeve 62 is provided on the outer rotating sleeve of the lower end of the liquid discharge cylinder 41, and the external threaded sleeve 62 is threadedly connected in the threaded hole 61.

[0031] The position of the liquid discharge cylinder 41 can be adjusted in the up and down directions by rotating the external threaded sleeve 62 in the threaded hole 61 at the corresponding position according to the number of liquid discharge cylinders 41 to be used; that is, the antibody reagent in the filling machine body 2 flows into the regulating box 31 through the liquid discharge pipe of the filling machine body 2. When the liquid level of the antibody reagent is higher than the upper end of the liquid discharge cylinder 41, the antibody reagent can enter the liquid discharge cylinder 41; when the liquid level of the antibody reagent is lower than the upper end of the liquid discharge cylinder 41, the antibody reagent cannot enter the liquid discharge cylinder 41.

[0032] Example 3 Based on the first embodiment, Figure 1 and Figure 3 As shown, a transparent observation window 311 is provided on the top surface of the regulating box 31; it is convenient to observe the capacity of the antibody reagent in the regulating box 31; at the same time, it is also convenient to observe the position of the top of the liquid discharge cylinder 41 and the positional relationship between the antibody reagent liquid level in the regulating box 31 according to the need to use the liquid discharge cylinder 41.

[0033] Example 4 Based on the first embodiment, Figure 3 and Figure 4 As shown, a hollow hemispherical cover 411 is movably provided at the lower end of the liquid discharge cylinder 41, and the filling tube 42 is located in the arc-shaped opening of the hollow hemispherical cover 411; when filling is not required, the hollow hemispherical cover 411 can be installed at the lower end of the liquid discharge cylinder 41, thereby protecting the filling tube 42 and preventing the filling tube 42 from being contaminated by the outside or damaged by touch.

[0034] Example 5 Based on the first embodiment, Figure 1 、 Figures 3 to 5 、 Figure 8As shown, a plate rack 7 is provided below the liquid discharge cylinder 41, and the plate rack 7 includes a left rack 71; the left rack 71 and the right rack 72 are arranged in parallel and spaced apart below the liquid discharge cylinder 41, and the grid placement plate 51 is slidably arranged between the left rack 71 and the right rack 72; there are two plate grooves 73, and a plate groove 73 is respectively provided on the side wall of the left rack 71 and the side wall of the right rack 72; the size of the cross-section of the plate groove 73 is adapted to the size of the cross-section of the grid placement plate 51; sliders 511 are provided at both opposite ends of the grid placement plate 51, and the two sliders 511 correspond to the positions of the two regulating cylinders 52 respectively, and an internal threaded hole 512 is provided in the top surface of the slider 511, and a threaded rod 513 is coaxially provided on the piston rod of the regulating cylinder 52, and the threaded rod 513 is respectively threadedly connected to the internal threaded hole 512 at the corresponding position; during filling Before the operation (and after a corresponding number of containers containing antibody reagents are placed in the grids of the grid placement plate 51 respectively), the grid placement plate 51 can be moved toward the liquid discharge cylinder 41 by adjusting the cylinder 52, so that the filling tube 42 can be inserted into the opening of the container containing antibody reagent at the corresponding position (to prevent leakage during filling), thereby facilitating the filling operation; at the same time, after the filling operation is completed, the grid placement plate 51 can be moved away from the liquid discharge cylinder 41 by adjusting the cylinder 52. When the position of the grid placement plate 51 is matched with the position of the plate groove 73, the threaded rod 513 can be rotated in the internal threaded hole 512 and the threaded rod 513 can be disengaged from the internal threaded hole 512, so that the grid placement plate 51 can be pulled out and removed from the plate groove 73 on the side wall of the left frame 71 or the plate groove 73 on the side wall of the right frame 72.

[0035] The open top of the plate groove 73 is provided with a slider groove 731 that is adapted to the size of the slider 511, and the slider 511 is slidably set in the slider groove 731 at the corresponding position; the opposite ends of the fixed plate 6 are vertically penetrated by guide rods 63, and the guide rods 63 movably penetrate the opposite ends of the grid placement plate 51 away from the end of the fixed plate 6, and the distance from the end of the guide rod 63 away from the fixed plate 6 to the bottom surface of the frame 1 is greater than the distance from the plate groove 73 to the bottom surface of the frame 1; it is convenient to adjust the cylinder 52 to drive the grid placement plate 51 to move towards or away from the liquid discharge cylinder 41, and the slider 511 can move in the slider groove 731 at the corresponding position, which is beneficial to keep the grid placement plate 51 moving smoothly; at the same time, when the grid placement plate 51 moves, the guide rod 63 can play a guiding role, which is also beneficial to keep the grid placement plate 51 in a stable position when moving.

[0036] Obviously, those skilled in the art may make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if such changes and modifications fall within the scope of the claims and their equivalents, the present invention is intended to include such changes and modifications.

Claims

1. An antibody filling machine, characterized in that: include: Rack (1); A filling machine body (2), the filling machine body (2) being arranged on the frame (1); A regulating box assembly (3), the regulating box assembly (3) is arranged on the liquid outlet pipe of the filling machine body (2); A filling head assembly (4), the filling head assembly (4) is movably arranged on the bottom surface of the regulating box assembly (3); A filling bottle placement assembly (5), the filling bottle placement assembly (5) is movably arranged below the filling head assembly (4); The regulating box assembly (3) includes a regulating box (31) connected to the liquid outlet pipe of the filling machine body (2); the bottom surface of the regulating box (31) is open, and a grid structure plate (32) is horizontally arranged in the opening of the bottom surface of the regulating box (31); and an elastic partition plate (33) is arranged in each grid of the grid structure plate (32); The filling head assembly (4) includes a plurality of liquid discharge cylinders (41) corresponding to the elastic partitions (33) one by one. The liquid discharge cylinders (41) are respectively vertically penetrated on the elastic partitions (33) at corresponding positions. The upper end of the liquid discharge cylinder (41) is open, and a filling tube (42) is provided in the lower end of the liquid discharge cylinder (41). The filling bottle placement assembly (5) includes a grid placement plate (51) movably arranged below the liquid discharge cylinder (41), the positions of the grids of the grid placement plate (51) corresponding to the positions of the grids of the grid structure plate (32), and regulating cylinders (52) on opposite sides of the top of the frame (1), wherein opposite ends of the grid placement plate (51) are respectively connected to the piston rods of the two regulating cylinders (52).

2. The antibody filling machine according to claim 1, characterized in that: The distance from the outlet of the liquid outlet pipe of the filling machine body (2) to the top surface of the grid structure plate (32) is smaller than the distance from the upper end of the liquid outlet cylinder (41) to the top surface of the grid structure plate (32).

3. The antibody filling machine according to claim 2, characterized in that: A fixed plate (6) is provided between the grid structure plate (32) and the grid placement plate (51). The fixed plate (6) is provided with a plurality of threaded holes (61) corresponding one to one with the liquid discharge cylinders (41). An external threaded sleeve (62) is provided on the outer rotation sleeve of the lower end of the liquid discharge cylinder (41). The external threaded sleeve (62) is threadedly connected in the threaded hole (61).

4. The antibody filling machine according to claim 1, characterized in that: A transparent observation window (311) is provided on the top surface of the regulating box (31).

5. The antibody filling machine according to claim 1, characterized in that: A hollow hemispherical cover (411) is movably provided at the lower end of the liquid discharge cylinder (41), and the filling tube (42) is located in the arc-shaped opening of the hollow hemispherical cover (411).

6. The antibody filling machine according to claim 1, characterized in that: A plate rack (7) is provided below the liquid discharge cylinder (41), and the plate rack (7) includes: Left rack (71); The right frame (72), the left frame (71) and the right frame (72) are arranged in parallel and spaced apart below the liquid discharge cylinder (41), and the grid placement plate (51) is slidably arranged between the left frame (71) and the right frame (72); Two plate grooves (73) are provided, and one plate groove (73) is provided on the side wall of the left frame (71) and the side wall of the right frame (72).

7. The antibody filling machine according to claim 6, characterized in that: The size of the cross section of the plate groove (73) is adapted to the size of the cross section of the grid placement plate (51).

8. The antibody filling machine according to claim 6, characterized in that: The grid placement plate (51) is provided with sliders (511) at both opposite ends. The two sliders (511) correspond to the positions of the two regulating cylinders (52) respectively. An internal threaded hole (512) is provided in the top surface of the slider (511). A threaded rod (513) is provided on the piston rod of the regulating cylinder (52) for coaxial rotation. The threaded rod (513) is threadedly connected to the internal threaded holes (512) at corresponding positions.

9. The antibody filling machine according to claim 8, characterized in that: A slider groove (731) having a size matching that of the slider (511) is provided at the top of the opening of the plate groove (73), and the slider (511) is slidably arranged in the slider groove (731) at a corresponding position.

10. The antibody filling machine according to claim 6, characterized in that: The fixed plate (6) has guide rods (63) vertically extending through both opposite ends thereof. The guide rods (63) extend away from the fixed plate (6) and movably extend through the opposite ends of the grid placement plate (51). The distance from the end of the guide rods (63) away from the fixed plate (6) to the bottom surface of the frame (1) is greater than the distance from the plate slot (73) to the bottom surface of the frame (1).

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