Portable vaccine heat preservation device for non-electric environment

Abstract

The invention belongs to the technical field of vaccine heat preservation, particularly relates to a portable vaccine heat preservation device for a non-electric environment, and provides the following scheme aiming at the problems that an existing device is short in vaccine heat preservation time efficiency, large in medicine taking cooling capacity loss and difficult in temperature monitoring in the non-electric environment. Comprising a heat preservation outer box, a transmission belt assembly, a vaccine positioning seat and a phase change heat preservation assembly, the loss rate of low temperature in the box when vaccines are taken every time is reduced, and the mode that phase change temperature control of the phase change heat preservation assembly, vacuum heat insulation of a vacuum cavity and reflection of external heat radiation of an anti-radiation film layer are combined is adopted; through the synergistic effect of vacuum heat insulation, heat reflection and phase change materials, passive temperature control is achieved, a dual temperature control mechanism of passive isolation and active temperature adjustment is formed in the aspects of heat preservation and temperature control, the device is suitable for being used in the outdoor environment without a power source and the like, the emergency cold storage unit is combined with the manual triggering unit, and cooling capacity releasing on demand under the condition without the power source is achieved.

Description

Technical Field

[0001] The present invention relates to a vaccine heat preservation device, in particular to a portable vaccine heat preservation device for use in a non-electrical environment, belonging to the technical field of vaccine heat preservation. Background Art

[0002] Vaccine storage and transportation must be maintained within a strict temperature range of 2-8°C to maintain their biological activity. This requirement is clearly listed as a core standard in the World Health Organization (WHO)'s "Good Vaccine Management Guidelines." While electric refrigeration equipment can achieve precise temperature control, it is completely unsuitable for remote areas without power grid coverage, disaster relief sites, or mobile vaccination scenarios. Traditional passive insulated boxes rely on dry ice or ice blocks as a cooling source, which has systemic flaws such as intermittent cooling, large temperature fluctuations, and sudden drops in cooling capacity caused by repeated opening of the lid to remove medication.

[0003] In the prior art, active temperature control devices, such as the vaccine insulation and transfer device disclosed in announcement number CN117029372A, achieve temperature control through refrigeration plates and motor heat recovery, but still require batteries to drive the refrigeration system, and their endurance is severely limited in an off-electric environment, and the complex electrical structure significantly increases the failure rate and maintenance costs; passive insulation boxes, such as the cold chain transport aviation transfer box disclosed in announcement number CN218087050U, use sustained-release packaging to delay the release of refrigerant. Although it reduces dependence on electricity, the box needs to be opened as a whole when storing and accessing vaccines. Repeated operations cause the temperature inside the box to fluctuate violently, and there is a lack of emergency cooling supply mechanism under sudden high temperatures. It does not solve the problem of heat loss control during vaccine storage and access. The overall opening cover design causes the heat exchange area in the box to be too large, and there is a lack of active control mechanism to deal with sudden temperature fluctuations. When the external environment suddenly rises to 35°C, the temperature inside the box will exceed the safety threshold within 2 hours. What is more serious is that the WHO guidelines require that the single storage and access time of vaccines must be controlled within 10 seconds and the temperature drift must be ≤1°C. Due to structural limitations, existing devices are difficult to meet the dual requirements of storage and access efficiency and temperature control accuracy at the same time; passive storage devices such as the medical vaccine insulation and transportation device disclosed in announcement number CN113247464A achieve directional access through annular storage grooves and waiting grooves, but the thermal resistance of the single-layer insulation structure is insufficient. It can only maintain an effective temperature for 4-6 hours in an environment above 30°C, which cannot meet the needs of long-term transportation.

[0004] A more prominent contradiction is that existing passive insulation technologies fail to address the synergistic issues of "on-demand access" and "temperature stability." For example, the phase-change material insulated box disclosed in announcement number CN207292997U, while retractable and adjustable in volume, is in direct contact with the vaccine storage area and the phase-change material, requiring the entire storage area to be exposed when accessing a single vaccine. Independent packaging solutions, such as the aforementioned medical vaccine insulation and transport device, utilize a rotating disk to cover the access hole. While this reduces the exposed area, the phase-change material is only distributed at the bottom of the box, resulting in a vertical temperature gradient of 3-5°C, violating the WHO's temperature uniformity requirements. Furthermore, temperature monitoring has long relied on electronic sensors, and the aforementioned vaccine insulation and transport device utilizes a control panel to display the temperature, rendering it functionally inoperable in an off-grid environment. Summary of the Invention

[0005] The present invention provides a portable vaccine insulation device for a powerless environment to solve the problems of short vaccine insulation time, large loss of cold water during drug extraction and difficulty in temperature monitoring in existing devices in a powerless environment.

[0006] The present invention achieves the above-mentioned object through the following technical solutions: a portable vaccine insulation device for use in a non-electrical environment, comprising an insulation outer box, a transmission belt assembly and a plurality of vaccine positioning seats provided in the insulation outer box, the vaccine positioning seats being evenly distributed and connected to the transmission belt assembly, a phase change insulation assembly further provided in the insulation outer box, an outer wall of the insulation outer box being coated with an anti-radiation film layer, a vacuum chamber being provided in the box body of the insulation outer box, a take-and-place hole being provided on the upper end surface of the insulation outer box, and the take-and-place hole being provided directly above one of the vaccine positioning seats; The phase-change insulation component includes a phase-change insulation outer layer and a phase-change insulation shell. The phase-change insulation outer layer has an outer inner cavity. Both the phase-change insulation outer layer and the phase-change insulation shell are filled with a phase-change liquid with a phase-change temperature range of 2-8°C. The phase-change insulation outer layer is tightly attached to the inner wall of the insulation outer box. The phase-change insulation shell is connected to the middle part of the insulation outer box. Several vaccine positioning seats are located on the outside of the phase-change insulation shell. An emergency cold storage unit is provided in the phase change insulation shell. The emergency cold storage unit includes a plurality of emergency cold storage tubes. The emergency cold storage tubes are filled with metastable supercooled liquid. A manual trigger unit is provided at the bottom of the emergency cold storage tube.

[0007] As a further solution of the present invention: a stepped docking surface is provided on the upper end of the box body of the thermal insulation outer box, a docking bottom groove is provided on the bottom end of the box body of the thermal insulation outer box, and the docking bottom groove and the stepped docking surface can be matched and docked, and a box cover is also movably connected to the top of the thermal insulation outer box.

[0008] As a further solution of the present invention: the body of the heat-insulating outer box is affixed with a thermochromic liquid crystal patch, and the color-developing temperature range of the thermochromic liquid crystal patch is 2-8°C.

[0009] As a further solution of the present invention: a rotating rod is provided at the driving end of the transmission belt assembly, a through-hole is provided on the upper end of the heat-insulating outer box, the shaft of the rotating rod movably passes through the through-hole, the inner wall of the through-hole is provided with symmetrically arranged positioning slots, the shaft of the rotating rod located in the through-hole is connected to symmetrically arranged positioning balls, and the positioning balls are movably clamped in the positioning slots, and the spacing between two adjacent vaccine positioning seats is equal to the transmission distance of the driving transmission belt assembly when the rotating rod rotates 180°; A sealing cover is arranged in the taking-and-putting hole, an inner wall of the taking-and-putting hole is provided with an inner frosted surface, and a side wall of the sealing cover is provided with an outer frosted surface.

[0010] As a further solution of the present invention: the transmission belt assembly includes a transmission belt and two transmission rollers, the transmission belt is sleeved on the roller bodies of the two transmission rollers, a number of vaccine positioning seats are respectively connected to the outer belt body of the transmission belt, the transmission rollers are arranged on both sides of the middle shell body of the phase change insulation shell, the transmission rollers are coaxially fixedly connected with a transmission rod, both ends of the transmission rod are rotatably connected in the phase change insulation shell, and one of the transmission rods is set as the driving end of the transmission belt assembly; the inner belt body of the transmission belt is provided with a strip friction pattern, and the roller body of the transmission roller is provided with an annular friction pattern.

[0011] As a further solution of the present invention: the vaccine positioning seat includes a positioning ring and a connecting plate, the positioning rings are arranged in parallel, the connecting plate is connected between the two positioning rings, and an annular support base plate is fixedly connected to the positioning ring at the bottom end. The connecting plates are distributed in a cross shape, and several positioning protrusions are embedded in the inner plate body of the connecting plate.

[0012] As a further solution of the present invention: the phase change insulation shell is fixedly connected to the bottom surface of the insulation outer box, including an end shell body and a middle concave shell body, the end shell body is respectively connected to the upper and lower ends of the middle concave shell body, and an insulation shell inner cavity is opened in the end shell body and the middle concave shell body of the phase change insulation shell, and a plurality of shell cavity inner tubes are connected to the insulation shell inner cavity, and the open bottom end of the shell cavity inner tube is located outside the bottom surface of the insulation outer box.

[0013] As a further solution of the present invention, an emergency cold storage tube is movably inserted in the tube in the shell cavity, a bottom hole is provided at the bottom of the emergency cold storage tube, and a sealing membrane is connected in the bottom hole.

[0014] As a further solution of the present invention: the manual trigger unit includes a blocking base and an ejector pin, the ejector pin is movably arranged in the blocking base, and the blocking base is clamped on the open bottom end of the tube in the shell cavity.

[0015] As a further solution of the present invention, the body of the blocking base is provided with a connected push plate movable cavity and an ejector movable cavity, a push plate is movably arranged in the push plate movable cavity, the ejector is movably inserted in the ejector movable cavity and the push plate movable cavity, the bottom end of the ejector is connected to the push plate, the needle body of the ejector located in the push plate movable cavity is provided with a compression spring in a compressed state, the inner wall of the push plate movable cavity is connected to a limiting block, and the push plate is against the limit block directly above the limit block; a blocking cover is movably placed at the bottom opening of the push plate movable cavity.

[0016] The beneficial effects of the present invention are: 1. The present invention is provided with an insulation outer box, a transmission belt assembly and a plurality of vaccine positioning seats are arranged in the insulation outer box, a phase change insulation assembly is further arranged in the insulation outer box, the outer wall of the insulation outer box is coated with an anti-radiation film layer, the box body of the insulation outer box is provided with a vacuum chamber, the upper end surface of the insulation outer box is provided with a take-and-place hole, and the opening position of the take-and-place hole is located directly above one of the vaccine positioning seats, and the vaccine positioning seat is used to fix the vaccine bottle to ensure that the vaccine can be stably placed in the insulation outer box, and under the rotation action of the transmission belt assembly, the vaccine positioning seat can be rotated in a circle along the transmission track of the transmission belt assembly, thereby ensuring that each vaccine positioning seat can be rotated to directly below the take-and-place hole, that is, it is convenient to take the vaccine The vaccine stored in the box can be taken out conveniently through a take-and-place hole. Therefore, each time the vaccine is taken out, the traditional method of opening a large opening of the insulation device is improved, and the loss rate of low temperature in the box each time the vaccine is taken out is greatly reduced. There is a significant improvement in the design of the box structure, and the phase change temperature control of the phase change insulation component, the vacuum insulation of the vacuum cavity and the reflection of the external heat radiation by the anti-radiation film layer are combined. Through the synergistic effect of vacuum insulation, heat reflection and phase change materials, passive temperature control is achieved, and a dual temperature control mechanism of "passive isolation + active temperature regulation" is formed in terms of thermal insulation and temperature control. It has outstanding substantial characteristics and is suitable for use in outdoor environments without power supply. 2. The phase change insulation component provided by the present invention includes a phase change insulation outer layer and a phase change insulation shell. The phase change insulation outer layer and the phase change insulation shell are filled with a phase change liquid with a phase change temperature range of 2-8°C. The phase change insulation outer layer is tightly attached to the inner wall of the insulation outer box. The phase change insulation shell is connected to the middle part of the insulation outer box. Several vaccine positioning seats are located on the outside of the phase change insulation shell. Since the phase change liquid has the latent heat absorption / release characteristics during the phase transition of the material, when the ambient temperature is higher than the phase transition temperature of the phase change liquid, the solid phase The phase-change liquid absorbs heat and melts into liquid, storing a large amount of heat in the form of latent heat, thereby maintaining a stable temperature inside the insulation outer box. In addition, the phase-change insulation outer layer and the interior of the phase-change insulation shell are both filled with phase-change liquid, which can distribute the phase-change liquid in multiple areas inside the insulation outer box, so that the temperature inside the insulation outer box is kept in a balanced state of 2-8°C. Each vaccine bottle can be in the same stable low-temperature environment, making the insulation effect better. In addition, the use of phase-change liquid for low-temperature insulation can meet WHO vaccine storage standards. 3. The phase change insulation shell provided in the present invention is provided with an emergency cold storage unit, which includes several emergency cold storage tubes. The emergency cold storage tubes are filled with metastable supercooled liquid. The bottom end of the emergency cold storage tube is provided with a manual trigger unit. When the metastable supercooled liquid is mechanically stimulated, it will provide heterogeneous nucleation points for the liquid. The nucleation points cause the molecules of the metastable supercooled liquid to be arranged in an orderly manner, and crystallize rapidly in the solution. During the crystallization process, the ambient heat is absorbed to achieve rapid cooling of the phase change insulation shell, and the vaccine in the insulation outer box can be suddenly supplied with cold capacity without electricity. The manual trigger unit can be used to trigger the emergency cold storage unit in a targeted manner according to the specific situation. By combining the crystallization cooling of the emergency cold storage unit with the selective triggering of the manual trigger unit, "cold capacity release on demand" without power is achieved. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the bottom structure of the thermal insulation outer box of the present invention; Figure 3 For the present invention Figure 1 Schematic diagram of the cross-section structure at point A in the middle; Figure 4 This is a schematic diagram of the top view of the heat-insulating outer box and the transmission belt assembly of the present invention; Figure 5 This is a schematic diagram of the connection structure between the thermal insulation outer box and the phase change thermal insulation shell of the present invention; Figure 6 For the present invention Figure 5 Schematic diagram of the structure at B in the middle; Figure 7 This is a schematic diagram of the connection structure between the transmission belt assembly and the vaccine positioning seat of the present invention; Figure 8 This is a schematic structural diagram of the transmission belt assembly of the present invention; Figure 9 This is a schematic diagram of the vaccine positioning seat structure of the present invention; Figure 10 This is a schematic diagram of the connecting plate structure of the present invention; Figure 11 This is a schematic diagram of the three-dimensional structure of the phase change insulation shell of the present invention; Figure 12 Schematic diagram of the cross-sectional structure of the phase change insulation shell of the present invention; Figure 13 Schematic diagram of the cross-sectional structure of the emergency cold storage unit and the manual triggering unit of the present invention; Figure 14 For the present invention Figure 13 Schematic diagram of the structure at point C in the middle.

[0018] In the figure: 1. Insulated outer box; 11. Stepped docking surface; 12. Docking bottom groove; 13. Vacuum chamber; 14. Anti-radiation film layer; 15. Positioning slot; 16. Pick-up and drop hole; 17. Inner frosted surface; 18. Perforation; 2. Box cover; 3. Thermochromic liquid crystal patch; 4. Transmission belt assembly; 41. Transmission belt; 42. Transmission roller; 43. Transmission rod; 44. Rotating rod; 45. Positioning ball; 46. Strip friction pattern; 47. Annular friction pattern; 5. Vaccine positioning seat; 51. Positioning ring; 52. Connecting plate; 5 3. Annular support base plate; 54. Positioning protrusion; 6. Phase change insulation outer layer; 61. Inner cavity of outer layer; 7. Phase change insulation shell; 71. End shell body; 72. Middle concave shell body; 73. Shell cavity inner tube; 74. Emergency cold storage tube; 75. Bottom hole; 76. Sealing membrane; 77. Inner cavity of insulation shell; 8. Sealing base; 81. Push plate movable cavity; 82. Ejector pin movable cavity; 83. Push plate; 84. Ejector pin; 85. Compression spring; 86. Limit block; 87. Sealing cover; 9. Sealing cover; 91. External frosted surface. DETAILED DESCRIPTION

[0019] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0020] Example 1 like Figures 1 to 14As shown, a portable vaccine insulation device for a non-electrical environment includes an insulation outer box 1, a transmission belt assembly 4 and a plurality of vaccine positioning seats 5 are arranged in the insulation outer box 1, and the vaccine positioning seats 5 are evenly distributed and connected to the transmission belt assembly 4. A phase change insulation assembly is also provided in the insulation outer box 1, and the outer wall of the insulation outer box 1 is coated with an anti-radiation film layer 14. The box body of the insulation outer box 1 is provided with a vacuum cavity 13, and the upper end surface of the insulation outer box 1 is provided with a taking and placing hole 16, and the opening position of the taking and placing hole 16 is located directly above one of the vaccine positioning seats 5. The vaccine positioning seat 5 is used to fix the vaccine bottle to ensure that the vaccine can be stably placed in the insulation outer box 1, and under the rotation of the transmission belt assembly 4, the vaccine positioning seat 5 can be made to rotate in a circle along the transmission track of the transmission belt assembly 4, thereby ensuring that each The vaccine positioning seats 5 can be rotated to the bottom of the access hole 16, which is convenient for taking out the vaccine. The vaccine stored in the box can be easily taken out through the access hole 16. Therefore, each time the vaccine is taken out, the traditional method of taking out the vaccine by opening a large opening of the thermal insulation device is improved, and the loss rate of the low temperature in the box each time the vaccine is taken out is greatly reduced. There is a significant improvement in the design of the box structure, and the phase change temperature control of the phase change thermal insulation component, the vacuum insulation of the vacuum cavity 13 and the reflection of the external heat radiation of the anti-radiation film layer 14 are combined. Through the synergistic effect of vacuum insulation, heat reflection and phase change material, passive temperature control is achieved, and a dual temperature control mechanism of "passive isolation + active temperature regulation" is formed in terms of thermal insulation and temperature control. It has outstanding substantial characteristics and is suitable for use in outdoor environments without power supply. The phase change insulation component includes a phase change insulation outer layer 6 and a phase change insulation shell 7. The phase change insulation outer layer 6 is provided with an outer layer inner cavity 61. The phase change insulation outer layer 6 and the phase change insulation shell 7 are filled with a phase change liquid with a phase change temperature range of 2-8°C. The phase change insulation outer layer 6 is tightly attached to the inner wall of the insulation outer box 1. The phase change insulation shell 7 is connected to the middle part of the box of the insulation outer box 1. Several vaccine positioning seats 5 are all located on the outside of the phase change insulation shell 7. It should be noted that the phase change liquid includes but is not limited to inorganic hydrated salts such as disodium hydrogen phosphate dodecahydrate, and its phase change temperature perfectly matches the vaccine storage requirements. When filling the phase change liquid, 10-15% of the reserved space is reserved to accommodate the expansion of the liquid phase change liquid. Since the phase change liquid has the latent heat absorption / release characteristics during the phase transition of the material, when the ambient temperature is higher than the phase change temperature of the phase change liquid, the solid phase change liquid absorbs heat and melts into liquid, storing a large amount of heat in the form of latent heat, thereby maintaining the temperature inside the thermal insulation outer box 1 stable, and the interior of the phase change thermal insulation outer layer 6 and the phase change thermal insulation shell 7 are both filled with phase change liquid, that is, the phase change liquid can be distributed in multiple areas of the thermal insulation outer box 1, and the temperature inside the thermal insulation outer box 1 can be kept in a balanced state of 2-8°C. Each vaccine bottle can be in the same stable low-temperature environment, so that the insulation effect is better, and the measure of using phase change liquid for low-temperature insulation can meet the WHO vaccine storage standards; An emergency cold storage unit is provided in the phase change insulation shell 7. The emergency cold storage unit includes several emergency cold storage tubes 74. The emergency cold storage tubes 74 are filled with metastable supercooled liquid. The bottom of the emergency cold storage tube 74 is provided with a manual trigger unit. It should be noted that the metastable supercooled liquid includes but is not limited to a saturated solution of sodium acetate trihydrate. When the metastable supercooled liquid is filled, 15% of the space is reserved to accommodate the expansion of the crystal volume. The inner wall of the emergency cold storage tube 74 is coated with a polytetrafluoroethylene hydrophobic layer to inhibit the spontaneous crystallization of the solution. Since the metastable supercooled liquid is mechanically stimulated, It will provide heterogeneous nucleation points for the liquid, and the nucleation points will cause the molecules of the metastable supercooled liquid to be arranged in an orderly manner, and crystallize rapidly in the solution. During the crystallization process, it will absorb environmental heat to achieve rapid cooling of the phase change insulation shell 7, and can provide sudden cold supply to the vaccine in the insulation outer box 1 under no-electricity conditions. The manual trigger unit can be used to trigger the emergency cold storage unit in a targeted manner according to the specific situation. By combining the crystallization cooling of the emergency cold storage unit with the selective triggering of the manual trigger unit, "cold release on demand" under no-power conditions is achieved.

[0021] Example 2 Improvements based on Example 1: like Figure 1 、 Figure 2 、 Figure 3 and Figure 6 As shown, the upper end of the body of the thermal insulation outer box 1 is provided with a stepped docking surface 11, and the bottom end of the body of the thermal insulation outer box 1 is provided with a docking bottom groove 12, and the docking bottom groove 12 can be matched with the stepped docking surface 11. The top of the thermal insulation outer box 1 is also movably connected to the box cover 2. By placing the box cover 2 on the stepped docking surface 11, the positioning connection between the box cover 2 and the thermal insulation outer box 1 can be achieved, that is, the upper end surface of the thermal insulation outer box 1 can be protected to avoid touching part of the structure of the upper end surface of the thermal insulation outer box 1 when carrying it in an outdoor environment without electricity. At the same time, through the docking bottom groove 12 and the stepped docking surface 11, multiple thermal insulation outer boxes 1 can be stacked and combined to form a structure similar to a layered lunch box, which is convenient to carry.

[0022] Furthermore, the body of the thermal insulation outer box 1 is affixed with a thermochromic liquid crystal patch 3, and the color display temperature range of the thermochromic liquid crystal patch 3 is 2-8°C. It should be noted that the material of the thermochromic liquid crystal patch 3 includes but is not limited to a mixture of cholesteryl nonanoate and cyanobiphenyl, which replaces traditional electronic sensors, integrates the optical properties of molecular self-assembly with engineering thermal design, and realizes visual temperature monitoring in a non-electric vaccine insulation environment, so that the carrier can accurately grasp the temperature conditions inside the box.

[0023] Furthermore, a rotating rod 44 is provided at the driving end of the transmission belt assembly 4, and a through-hole 18 is provided at the upper end of the heat-insulating outer box 1. The rod of the rotating rod 44 movably passes through the through-hole 18, and the inner wall of the through-hole 18 is provided with a positioning card slot 15 which is symmetrically arranged. The rotating rod 44 is located on the rod body in the through-hole 18 and is connected to a symmetrically arranged positioning ball 45, and the positioning ball 45 is movably carded in the positioning card slot 15. The spacing distance between two adjacent vaccine positioning seats 5 is equal to the transmission distance of the driving transmission belt assembly 4 when the rotating rod 44 rotates 180 degrees. When the rotating rod 44 is twisted by external force, a transmission driving force can be provided to the transmission belt assembly 4, thereby rotating the vaccine positioning seat 5 to the position directly below the access hole 16 in sequence, and the positioning ball 45 and the positioning slot 15 are engaged with each other, so that the positioning ball 45 and the positioning slot 15 are engaged once every 180° rotation of the rotating rod 44, that is, the operator can rotate the rotating rod 44 by the same angle each time, thereby ensuring that a vaccine positioning seat 5 is located directly below the access hole 16 each time, so as to facilitate the removal of the vaccine bottle; A sealing cover 9 is movably placed in the access hole 16, the inner wall of the access hole 16 is provided with an inner frosted surface 17, and the side wall of the sealing cover 9 is provided with an outer frosted surface 91. The sealing cover 9 can form a blockage for the access hole 16, and through the cooperation of the frosted surface, the firmness of the connection part is ensured, so that the sealing cover 9 is not easy to fall off, and the inside of the thermal insulation outer box 1 can be kept in a sealed state, which has a better thermal insulation effect.

[0024] like Figure 1 、 Figure 3 、 Figure 4 、 Figure 5 、 Figure 7 and Figure 8 As shown, the transmission belt assembly 4 includes a transmission belt 41 and two transmission rollers 42. The transmission belt 41 is sleeved on the roller bodies of the two transmission rollers 42. Several vaccine positioning seats 5 are respectively connected to the outer belt body of the transmission belt 41. The transmission rollers 42 are arranged on both sides of the middle shell body of the phase-changing thermal insulation shell 7. The transmission rollers 42 are coaxially fixedly connected with a transmission rod 43. The two ends of the transmission rod 43 are rotatably connected in the phase-changing thermal insulation shell 7, and one of the transmission rods 43 is set as the driving end of the transmission belt assembly 4. When the transmission rod 43 as the driving end drives one of the transmission rollers 42 to rotate, the transmission belt 41 can realize circular rotation, that is, it can drive the vaccine positioning seat 5 to move synchronously, and the transmission rod 43 is used to combine the transmission belt assembly 4 and the phase-changing thermal insulation shell 7 to connect them together, so that each vaccine positioning seat 5 can be in the same gap with the phase-changing thermal insulation shell 7, and each vaccine positioning seat 5 can be maintained in the same stable low-temperature environment; The inner belt body of the transmission belt 41 is provided with a strip friction pattern 46, and the roller body of the transmission roller 42 is provided with an annular friction pattern 47. Through the cooperation of the friction patterns, the friction force between the transmission belt 41 and the transmission roller 42 can be increased, thereby ensuring that the transmission roller 42 can stably drive the transmission belt 41 to rotate in a circle.

[0025] like Figure 4 、 Figure 7 、 Figure 9 and Figure 10 As shown, the vaccine positioning seat 5 includes a positioning ring 51 and a connecting plate 52. The positioning rings 51 are arranged in parallel, and the connecting plate 52 is connected between the two positioning rings 51. The positioning ring 51 at the bottom end is fixedly connected to an annular support base plate 53. The connecting plate 52 is distributed in a cross shape, and a plurality of positioning protrusions 54 are embedded in the inner plate body of the connecting plate 52. The vaccine bottle can be limited and placed by the hollow seat body formed by the positioning ring 51, the connecting plate 52 and the annular support base plate 53, and the low temperature in the box can be directly applied to the bottle body of the vaccine bottle, thereby achieving a better low-temperature preservation effect. The positioning protrusions 54 can fix the vaccine bottle placed in the vaccine positioning seat 5 to prevent the vaccine bottle from falling out of the positioning seat.

[0026] like Figure 4 、 Figure 5 、 Figure 11 、 Figure 12 and Figure 13 As shown, the phase change insulation shell 7 is fixedly connected to the bottom surface of the insulation outer box 1, including an end shell body 71 and a middle concave shell body 72. The end shell body 71 is respectively connected to the upper and lower ends of the middle concave shell body 72. An insulation shell inner cavity 77 is opened in the end shell body 71 and the middle concave shell body 72 of the phase change insulation shell 7. A plurality of shell cavity inner tubes 73 are connected to the insulation shell inner cavity 77, and the open bottom end of the shell cavity inner tube 73 is located on the outside of the bottom surface of the insulation outer box 1. The middle concave shell body 72 is provided to make the middle shell body of the phase change insulation shell 7 have a concave space, thereby providing an installation position for the transmission belt assembly 4, and the provided shell cavity inner tube 73 can facilitate the placement of the emergency cold storage tube 74 from the bottom of the insulation outer box 1.

[0027] Furthermore, an emergency cold storage tube 74 is movably inserted in the shell cavity inner tube 73, and a bottom hole 75 is provided at the bottom of the emergency cold storage tube 74. A sealing membrane 76 is connected to the bottom hole 75. The bottom hole 75 is opened to facilitate the manual triggering unit to provide mechanical stimulation to the metastable supercooled liquid in the tube through the sealing membrane 76, so as to trigger the emergency cold storage unit to perform emergency cold storage treatment on the vaccine bottle in the thermal insulation outer box 1.

[0028] like Figure 13 and Figure 14As shown, the manual trigger unit includes a sealing base 8 and a ejector pin 84. The ejector pin 84 is movably arranged in the sealing base 8. The sealing base 8 is clamped on the open bottom end of the shell cavity inner tube 73. The emergency cold storage tube 74 can be stably placed in the shell cavity inner tube 73 through the provided sealing base 8, and the movably arranged ejector pin 84 can be aligned with the sealing membrane 76. Therefore, the ejector pin 84 is pushed upward to pierce the sealing membrane 76, thereby triggering the supercooled liquid to instantly crystallize and release latent heat. It should be noted that the sealing base 8 can also be connected to the open bottom end of the shell cavity inner tube 73 through a threaded engagement connection.

[0029] Furthermore, the body of the blocking base 8 is provided with a connected push plate movable cavity 81 and an ejector movable cavity 82, wherein a push plate 83 is movably arranged in the push plate movable cavity 81, and an ejector pin 84 is movably inserted in the ejector movable cavity 82 and the push plate movable cavity 81, and the bottom end of the ejector pin 84 is connected to the push plate 83, and the needle body of the ejector pin 84 located in the push plate movable cavity 81 is provided with a compression spring 85 in a compressed state, and the inner wall of the push plate movable cavity 81 is connected to a limit block 86, and the push plate 83 is against the upper part of the limit block 86; through the cooperation of the compression spring 85 and the limit block 86, the ejector pin 84 can be stored in the blocking base 8 in the initial state. When the emergency cold storage tube 74 needs to be triggered, it is only necessary to press the push plate 83 to push the ejector pin 84 out of the blocking base 8, so that the top end of the ejector pin 84 can pierce the sealing membrane 76, and the triggering method is simple and convenient; A blocking cover 87 is movably placed on the bottom opening of the push plate movable cavity 81 to block the bottom opening of the push plate movable cavity 81 to prevent the ejector pin 84 from being lifted up due to accidental contact, that is, to prevent the emergency cold storage tube 74 from being triggered for crystallization refrigeration due to accidental contact.

[0030] Working Principle: The insulated outer box 1 provides basic protection: a vacuum chamber 13 within the box walls blocks heat conduction, while an anti-radiation film 14 reflects ambient heat radiation, significantly reducing external heat intrusion. The phase-change insulation assembly, serving as the temperature control hub, comprises an outer layer 6, clinging to the box walls, and a central shell 7. Both are filled with a phase-change fluid (such as disodium hydrogen phosphate dodecahydrate) whose phase-change temperature precisely matches the vaccine's required temperature (2-8°C). The fluid absorbs and releases latent heat during the solid-liquid phase transition. When the ambient temperature rises above the set range, the solid phase-change fluid melts into a liquid, absorbing excess heat to maintain a low temperature inside the box. As the temperature drops, it solidifies and releases heat, buffering against temperature fluctuations. The dual-zone layout (outer layer and central shell) ensures even distribution of cooling capacity and avoids localized temperature differences.

[0031] The vaccine storage and retrieval process optimizes cold storage through an innovative transmission structure: there is only a single retrieval hole 16 on the top of the box, and the vaccine positioning seat 5 with a ring drive corresponds to the hole directly below it. The positioning seat is driven by a transmission belt assembly 4, which contains a transmission belt 41 sleeved on a double transmission roller 42. The vaccine positioning seat 5 is evenly fixed on the outside of the belt body, and the vaccine positioning seat 5 is used to stabilize the vaccine bottle through the positioning protrusion 54; the rotating rod 44 extends to the outside of the box and controls the transmission through the positioning ball 45 and the positioning slot 15: with every half rotation, the transmission belt 41 moves one station accurately, so that the new vaccine bottle arrives under the retrieval hole 16. The user only needs to remove the sealing cover 9 to take the medicine, minimizing the escape of cold air.

[0032] The emergency cold storage unit is embedded in the phase-change insulation shell 7 and consists of multiple emergency cold storage tubes 74. The tubes are filled with a metastable supercooled liquid (such as a saturated solution of sodium acetate trihydrate), with 15% expansion space reserved. The inner wall is coated with polytetrafluoroethylene to inhibit spontaneous crystallization. A manual trigger unit is installed at the bottom of each tube: a sealing base 8 is fixed to the opening of the inner tube 73 of the shell cavity at the bottom of the insulation shell, and it contains a retractable ejector pin 84. Under normal conditions, the ejector pin 84 is locked by a compression spring 85 and a limit block 86, and the needle tip maintains a distance from the sealing membrane 76 at the bottom of the tube. When emergency cooling is required, the sealing cap 87 is removed and the push plate 83 is pressed. The ejector pin 84 breaks through the sealing membrane 76 and penetrates the solution, providing a nucleation point to trigger instantaneous crystallization, absorbing a large amount of heat and achieving rapid cooling. This design enables on-demand release of cooling under passive conditions.

[0033] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the invention can be embodied in other specific forms without departing from the spirit or essential characteristics of the invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be included therein. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

[0034] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. A portable vaccine insulation device for use in an environment without electricity, comprising an insulation outer box (1), characterized in that: The heat-insulating outer box (1) is provided with a transmission belt assembly (4) and a plurality of vaccine positioning seats (5), the vaccine positioning seats (5) are evenly distributed and connected to the transmission belt assembly (4), the heat-insulating outer box (1) is also provided with a phase change heat-insulating assembly, the outer wall of the heat-insulating outer box (1) is coated with an anti-radiation film layer (14), the body of the heat-insulating outer box (1) is provided with a vacuum cavity (13), the upper end surface of the heat-insulating outer box (1) is provided with a taking-in and putting hole (16), and the opening position of the taking-in and putting hole (16) is located directly above one of the vaccine positioning seats (5); The phase-change thermal insulation component includes a phase-change thermal insulation outer layer (6) and a phase-change thermal insulation shell (7), the phase-change thermal insulation outer layer (6) is provided with an outer layer inner cavity (61), the phase-change thermal insulation outer layer (6) and the phase-change thermal insulation shell (7) are both filled with a phase-change liquid with a phase-change temperature range of 2-8°C, the phase-change thermal insulation outer layer (6) is tightly attached to the inner wall of the thermal insulation outer box (1), the phase-change thermal insulation shell (7) is connected to the middle part of the thermal insulation outer box (1), and a plurality of the vaccine positioning seats (5) are all located on the outside of the phase-change thermal insulation shell (7); An emergency cold storage unit is provided in the phase change heat preservation shell (7), and the emergency cold storage unit comprises a plurality of emergency cold storage tubes (74). The emergency cold storage tubes (74) are filled with metastable supercooled liquid, and a manual trigger unit is provided at the bottom end of the emergency cold storage tube (74).

2. The portable vaccine warming device for a non-electrical environment according to claim 1, characterized in that: The upper end of the box body of the thermal insulation outer box (1) is provided with a stepped docking surface (11), the lower end of the box body of the thermal insulation outer box (1) is provided with a docking bottom groove (12), and the docking bottom groove (12) and the stepped docking surface (11) can be matched and docked, and the top of the thermal insulation outer box (1) is also movably connected to a box cover (2).

3. The portable vaccine warming device for a non-electrical environment according to claim 1, characterized in that: The body of the heat-insulating outer box (1) is affixed with a thermochromic liquid crystal patch (3), and the color-developing temperature range of the thermochromic liquid crystal patch (3) is 2-8°C.

4. The portable vaccine warming device for use in a non-electrical environment according to claim 1, characterized in that: The driving end of the transmission belt assembly (4) is provided with a rotating rod (44), the upper end box body of the heat-insulating outer box (1) is provided with a through hole (18), the rod body of the rotating rod (44) is movable through the through hole (18), the inner wall of the through hole (18) is provided with a symmetrically arranged positioning slot (15), the rotating rod (44) is located in the through hole (18) and is connected to a symmetrically arranged positioning ball (45), and the positioning ball (45) is movably clamped in the positioning slot (15), and the spacing distance between two adjacent vaccine positioning seats (5) is equal to the transmission distance of the driving transmission belt assembly (4) when the rotating rod (44) rotates 180°; A sealing cover (9) is movably mounted in the access hole (16), an inner wall of the access hole (16) is provided with an inner frosted surface (17), and a side wall of the sealing cover (9) is provided with an outer frosted surface (91).

5. The portable vaccine warming device for a non-electrical environment according to claim 1, characterized in that: The transmission belt assembly (4) includes a transmission belt (41) and two transmission rollers (42), the transmission belt (41) is sleeved on the roller bodies of the two transmission rollers (42), and a plurality of the vaccine positioning seats (5) are respectively connected to the outer belt body of the transmission belt (41), and the transmission rollers (42) are arranged on both sides of the middle shell body of the phase change insulation shell (7), and the transmission rollers (42) are coaxially fixedly connected to the transmission rod (43), and the two ends of the transmission rod (43) are rotatably connected in the phase change insulation shell (7), and one of the transmission rods (43) is set as the driving end of the transmission belt assembly (4); The inner belt body of the transmission belt (41) is provided with a strip friction pattern (46), and the roller body of the transmission roller (42) is provided with an annular friction pattern (47).

6. The portable vaccine warming device for a non-electrical environment according to claim 1, characterized in that: The vaccine positioning seat (5) includes a positioning ring (51) and a connecting plate (52), wherein the positioning rings (51) are arranged in parallel, and the connecting plate (52) is connected between the two positioning rings (51). An annular supporting base plate (53) is fixedly connected to the positioning ring (51) at the bottom end, and the connecting plate (52) is distributed in a cross shape, and a plurality of positioning protrusions (54) are embedded in the inner plate body of the connecting plate (52).

7. The portable vaccine warming device for use in a non-electrical environment according to claim 1, characterized in that: The phase-change thermal insulation shell (7) is fixedly connected to the bottom surface of the thermal insulation outer box (1), and comprises an end shell body (71) and a middle concave shell body (72), wherein the end shell body (71) is respectively connected to the upper and lower ends of the middle concave shell body (72), and a thermal insulation shell inner cavity (77) is provided in the end shell body (71) and the middle concave shell body (72) of the phase-change thermal insulation shell (7), wherein a plurality of shell cavity inner tubes (73) are connected in the thermal insulation shell inner cavity (77), and the open bottom ends of the shell cavity inner tubes (73) are located outside the bottom surface of the thermal insulation outer box (1).

8. The portable vaccine warming device for use in a non-electrical environment according to claim 7, characterized in that: An emergency cold storage tube (74) is movably inserted in the shell cavity inner tube (73), a bottom hole (75) is provided at the bottom of the emergency cold storage tube (74), and a sealing membrane (76) is connected to the bottom hole (75).

9. The portable vaccine warming device for use in a non-electrical environment according to claim 8, characterized in that: The manual trigger unit comprises a blocking base (8) and a thimble (84), wherein the thimble (84) is movably arranged in the blocking base (8), and the blocking base (8) is clamped on the open bottom end of the shell cavity inner tube (73).

10. The portable vaccine warming device for use in a non-electrical environment according to claim 9, characterized in that: The body of the blocking base (8) is provided with a push plate movable cavity (81) and an ejector pin movable cavity (82) which are connected to each other. A push plate (83) is movably arranged in the push plate movable cavity (81). The ejector pin (84) is movably inserted in the ejector pin movable cavity (82) and the push plate movable cavity (81). The bottom end of the ejector pin (84) is connected to the push plate (83). The needle body of the ejector pin (84) located in the push plate movable cavity (81) is provided with a compression spring (85) in a compressed state. The inner wall of the push plate movable cavity (81) is connected to a limit block (86), and the push plate (83) is against the limit block (86) directly above. A blocking cover (87) is movably mounted on the bottom opening of the push plate movable cavity (81).

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