Detection reaction device and method

Abstract

The invention relates to the technical field of detection, in particular to a detection reaction device which comprises a detection assembly, the detection assembly is of a hollow structure, a separation layer is arranged in the detection assembly and divides the interior of the detection assembly into a detection area and a drying area, a detection test piece is arranged in the detection area, a drying agent is arranged in the drying area, and a through hole is formed in the separation layer; the drying area is communicated with the detection area; the reaction assembly is detachably connected with the detection assembly, and a reaction cavity is formed in the reaction assembly and used for containing diluent; wherein the adjacent ends of the detection assembly and the reaction assembly are provided with sealing films for sealing when the detection assembly and the reaction assembly are installed, and when the detection assembly is inserted into the reaction assembly, the diluent flows into the detection area to be in contact with the detection test piece for detection.

Description

Technical Field

[0001] The present invention relates to the field of detection technology, and in particular to a detection reaction device and method. Background Art

[0002] In today's era of rapid advancement and booming medical diagnostic technology, rapid test consumables, with their unique advantages, have become an indispensable support for many key aspects of clinical diagnosis and treatment, disease prevention, and public health monitoring. These consumables often rely on specific biochemical reaction mechanisms and have the ability to quickly and accurately detect target analytes in various human samples (including blood, urine, and tissue fluid), providing timely and reliable data for medical decision-making.

[0003] However, the current detection reaction devices on the market face numerous challenges that need to be addressed. For one thing, the operating procedures of many detection reaction devices are extremely complex and tedious, requiring a high level of professional skills and operational experience from the testers. In practice, testers require extensive professional training to master the key operational points, which undoubtedly limits the widespread adoption of detection work.

[0004] On the other hand, existing detection reaction devices have significant structural design flaws. They are typically composed of multiple independent components, such as a heating module, a cooling module, and a detection module. These components lack effective integration and coordination, forcing testers to repeatedly transfer samples between different components during testing. This process not only consumes a significant amount of time and increases testing costs, but also significantly increases the risk of sample contamination due to the exposure of samples to the external environment during transfer. This can lead to errors in test results and affect the accuracy of medical diagnoses.

[0005] Furthermore, existing detection reaction devices are relatively simple in their functional design and can often only be customized for specific test items. They lack versatility and flexibility, making it difficult to meet the increasingly diverse testing needs. Furthermore, due to the influence of environmental humidity, test strips are extremely susceptible to moisture and deterioration. Once this occurs, the test strips cannot be used properly, which not only wastes resources but also may delay the testing process and cause unnecessary trouble to medical work.

[0006] Therefore, the present application has developed a detection reaction device and method to solve the problems existing in the prior art. Summary of the Invention

[0007] The purpose of the present invention is to provide a detection reaction device and method to solve the problem of inconvenient detection in the prior art.

[0008] The technical solution of the present invention is: a detection reaction device, comprising: The detection component has an internal hollow structure and a partition layer therein, which divides the interior of the detection component into a detection area and a drying area. The detection area contains a detection test piece, and the drying area contains a desiccant. The partition layer has a through hole, which connects the drying area and the detection area. A reaction component is detachably connected to the detection component, and a reaction chamber is provided inside the reaction component for containing a diluent; Wherein, when the detection component and the reaction component are installed, the adjacent ends are both provided with sealing films for sealing. When the detection component is inserted into the reaction component, the diluent flows into the detection area and contacts the detection test piece for detection.

[0009] Preferably, the detection component includes a partition and a detection part, the partition is detachably connected to the detection part, the detection test piece is provided in the detection part, and a partition plate is provided in the partition. When the partition is inserted into the reaction component, the partition plate divides the reaction chamber into multiple reaction spaces.

[0010] Preferably, a plurality of the test strips are provided and all are located in the detection area, and the plurality of test strips correspond one-to-one to the plurality of reaction spaces, respectively, for detecting different items.

[0011] Preferably, the separation layer includes a first separation plate and a second separation plate, the second separation plate is arranged along the axial direction of the detection component and is bent multiple times, the bending forms a bending area in the reaction chamber, providing an installation position for the detection test piece, the first separation portion is arranged perpendicular to the second partition, and is sealed and connected to one end of the second partition and the inner wall of the detection component.

[0012] Preferably, the through holes are provided through the first partition plate and are distributed in a circular array.

[0013] Preferably, the test strip is arranged axially along the detection component, and one end extends over the first partition plate, so that the height of the end of the test strip close to the reaction component is lower than the height of the partition plate.

[0014] Preferably, a puncture body is provided on the bottom surface of the reaction component, and the puncture body has a pointed end and faces the detection component.

[0015] Preferably, a contact portion is provided at one end of the reaction component away from the detection component, along the outer wall contour of the reaction component, and the outer wall surface of the contact portion is arranged at an angle to the outer wall surface of the reaction component.

[0016] Preferably, the detection reaction device is a transparent structure as a whole, so that changes in the detection test strip can be observed.

[0017] A detection reaction method comprises the following steps: S1: Dividing the reaction space: inserting the partition into the reaction chamber, piercing the sealing membrane with the puncture body, and dividing the reaction chamber into multiple reaction spaces with the partition plate; S2: adding different dilutions into different reaction spaces respectively; S3: dripping the solution to be tested into the reaction space and heating it; S4: Absorption of solution by the test strip: After the reaction in step S3 is completed, the detection part is inserted into the partition part to allow the diluent to flow into the test strip; S5: Observe the reaction results of the test strip and judge the test results according to the preset interpretation standards.

[0018] Compared with the prior art, the advantages of the present invention are: (1) A partition layer is set inside the detection component to divide the space into a detection area and a drying area. A desiccant is placed in the drying area, which is connected to the detection area through the through-holes on the partition layer to absorb moisture. A sealing film is provided at the adjacent end of the detection component and the reaction component, which plays a sealing role when the device is not in use. The desiccant is used to prevent the detection test piece from contacting with the outside world and absorbing moisture, resulting in deliquescence and deterioration, thereby ensuring the stability of the detection test piece; (2) After the partition is inserted into the reaction assembly, the partition plate divides the reaction chamber into multiple independent reaction spaces, providing independent environments for the reactions of different dilutions with the solution to be tested, avoiding mutual interference. In addition, multiple test strips are configured in the detection section, corresponding one-to-one to multiple reaction spaces, and can be designed for different detection items, realizing simultaneous detection of multiple different items, thereby improving detection efficiency and diversity. (3) The test strip is arranged along the axis of the test component, with one end extending over the first partition plate so that the height of the end close to the reaction component is lower than the height of the partition plate. When the device is not in use, the desiccant keeps the test strip stable through the through hole. During detection, the test strip is in contact with the diluent after the reaction first. The desiccant cannot contact the diluent due to its high height, avoiding reaction with the diluent and ensuring detection accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The present invention will be further described below with reference to the accompanying drawings and embodiments: Figure 1 This is a side sectional view of a detection reaction device according to the present invention; Figure 2 This is a schematic diagram of an explosion of a detection reaction device according to the present invention; Figure 3 This is a partial structural cross-sectional view of a detection reaction device according to the present invention; Figure 4 A top view of the separation layer of the present invention; Figure 5 The present invention provides a flow chart of a detection reaction method.

[0020] Among them: 1. Detection component; 11. Detection area; 12. Drying area; 13. Partition; 14. Detection part; 15. Partition plate; 2. Partition layer; 21. Through hole; 22. First partition plate; 23. Second partition plate; 24. Bending area; 3. Detection test piece; 4. Reaction component; 41. Reaction chamber; 42. Reaction space; 5. Puncture body; 51. Tip; 6. Contact part. DETAILED DESCRIPTION

[0021] The present invention will be described in further detail below with reference to specific embodiments: like Figure 1-Figure 3 As shown, a detection reaction device includes a detection component 1 and a reaction component 4. The detection component 1 adopts an internal hollow structure design and is provided with a separator layer 2. The separator layer 2 divides the internal space of the detection component 1 into two independent areas, namely a detection area 11 and a drying area 12. The detection area 11 contains a detection test piece 3, which is used to absorb the diluent after the reaction to obtain the test result. The drying area 12 contains a desiccant, which absorbs moisture within the device, maintains the detection environment dry, and prevents the detection test piece 3 from getting damp and deteriorating. In addition, the separator layer 2 is provided with through holes 21, which connect the drying area 12 and the detection area 11, allowing the desiccant to exert its drying effect and maintain the dry state of the detection area 11. The reaction component 4 and the detection component 1 are connected in a detachable manner to facilitate assembly and disassembly of the device. The reaction component 4 is provided with a reaction chamber 41 inside. The reaction chamber 41 is used to hold the diluent and plays a role in dissolving the sample and promoting the reaction during the detection process.

[0022] When the detection component 1 and the reaction component 4 are installed, a sealing film is provided at one adjacent end thereof. The sealing film plays a sealing role when the device is not in use, preventing the detection test strip 3 from contacting the outside world and absorbing moisture, thereby causing deliquesce and deterioration. A puncture body 5 is provided on the bottom surface of the reaction component 4, and the tip 51 of the puncture body 5 is facing the detection component 1. When detection is required, the diluent is first poured into the reaction chamber 41, and the liquid to be detected is dropped into the diluent. The liquid to be detected is reacted with the diluent by holding the reaction component 4 tightly or by electric heating or liquid heating. After the reaction is completed, the detection component 1 is inserted into the reaction component 4. As the insertion action proceeds, the sealing film is destroyed by the puncture body 5, and the diluent in the reaction chamber 41 flows into the detection area 11, fully contacting the detection test strip 3, thereby triggering a corresponding chemical reaction, and then completing the detection process.

[0023] Specifically, the detection reaction device is transparent as a whole. After the test strip 3 completes the detection reaction, there is no need to remove the test strip 3 from the detection component 1. The changes in the test strip 3 can be directly observed through the transparent detection component 1. Since the changes in the test strip 3 correspond to the test results, the test results can be directly obtained by simply observing the changes in the test strip 3. This method avoids the environmental pollution problem that may be caused by removing the test strip 3, and also reduces the number of operating steps in the detection process, thereby improving detection efficiency.

[0024] like Figure 5 As shown, the method for implementing the detection includes the following steps: S1: Separate the reaction space 42: Insert the partition 13 into the reaction chamber 41 of the reaction component 4. During the insertion process, the puncture body 5 provided on the reaction component 4 can pierce the sealing membrane provided on the partition 13, so that the reaction chamber 41 is connected with the outside world. At the same time, the partition plate 15 in the partition 13 plays a role, dividing the reaction chamber 41 into multiple independent reaction spaces 42, providing an independent environment for the subsequent reaction of different dilutions and the solution to be tested, thereby avoiding mutual interference between different reactions.

[0025] S2: Add different diluents into each reaction space 42 respectively, ensuring that the type and amount of diluent added to each reaction space 42 meet the requirements (for example, add 1 ml of diluent) to prevent excessive diluent from overflowing and polluting the environment.

[0026] S3: Drop the solution to be detected into each reaction space 42 to fully mix the solution to be detected with the diluent. Then, heat the reaction component 4. The heating method can be selected according to the actual situation, such as heating with a constant temperature heating device or heating by human body temperature, to promote the chemical reaction between the solution to be detected and the diluent, accelerate the reaction rate, and thus improve the sensitivity and accuracy of the detection.

[0027] S4: Absorption of solution by the detection strip 3: When the reaction in step S3 is completed, the detection part 14 is inserted into the partition part 13. When the detection part 14 is completely inserted into the partition part 13, the detection strip 3 is in full contact with the diluted solution after the reaction. The detection strip 3 will absorb the components in the solution, causing the detection strip 3 and the solution after the reaction to undergo a specific chemical reaction or physical change, providing a basis for subsequent result judgment.

[0028] S5: Determine the test result according to the preset interpretation standard, observe the reaction results on the test strip 3 through the transparent detection component 1, such as color change, line appearance, etc., to obtain the test result, and accurately and quickly determine whether the target pathogen or related indicators are present in the solution to be tested.

[0029] In this embodiment, Figure 2-Figure 3 As shown, the detection component 1 includes a partition 13 and a detection part 14, which adopts a detachable connection method. A partition plate 15 is provided inside the partition 13. When the partition 13 is inserted into the reaction component 4, the partition plate 15 can separate the reaction chamber 41 in the reaction component 4 into multiple independent reaction spaces 42. Initially, the partition 13 and the detection part 14 are installed together, and the internal dryness is ensured by the desiccant to ensure the stability of the detection test piece 3. The detachable design facilitates the disassembly of the partition 13 and the detection part 14, and the reaction chamber 41 is divided into multiple reaction spaces 42 by the partition plate 15. At the same time, a plurality of test strips 3 are configured in the detection section 14, and the plurality of test strips 3 are all located in the detection area 11 defined by the detection section 14. Moreover, the plurality of test strips 3 and the plurality of reaction spaces 42 separated by the partition plate 15 are in a one-to-one correspondence. Each test strip 3 can be designed for different detection items. During the detection process, samples in different reaction spaces 42 can react with the corresponding test strips 3 respectively, thereby realizing synchronous detection of multiple different items, improving detection efficiency and detection diversity.

[0030] Specifically, such as Figure 4 As shown, the partition layer 2 includes a first partition plate 22 and a second partition plate 23. Among them, the second partition plate 23 is arranged along the axial direction of the detection component 1 and is bent multiple times in a direction perpendicular to the axial direction. These bent parts form a specific bending area 24 in the reaction chamber 41 of the reaction component 4, providing a suitable installation position for the detection test piece 3, ensuring that the detection test piece 3 can be stably and accurately placed in the reaction chamber 41 so that it can be fully contacted with the diluent and tested later. At the same time, multiple detection test pieces 3 are separated to prevent contact with the same diluent and contamination. The first partition plate 22 is arranged perpendicular to the second partition plate 23. It is sealed with one end of the second partition plate 23 and the inner wall of the detection component 1, providing storage space for the desiccant and ensuring the stability and accuracy of the detection environment.

[0031] Furthermore, if Figure 3 As shown, the test strip 3 is arranged along the axial direction of the detection component 1, and one end of the test strip 3 extends and passes over the first partition plate 22, so that the test strip 3 is close to one end of the reaction component 4, and its height is lower than the height of the partition plate 15. At the same time, the first partition plate 22 is penetrated with through holes 21 and distributed in a circular array. In this way, when the device is not in use, the desiccant maintains the stability of the test strip 3 through the through holes 21. When the test is performed, the test strip 3 will preferentially contact the diluent after the reaction, and the desiccant cannot contact the diluent due to its high height, so that the desiccant will not react with the diluent, thereby ensuring the accuracy of the test.

[0032] In order to optimize the reaction effect between the liquid to be detected and the diluent, a contact portion 6 is provided at the end of the reaction component 4 away from the detection component 1. The contact portion 6 is arranged along the contour of the outer wall of the reaction component 4, and its shape is adapted to the contour of the outer wall of the reaction component 4 at this end. Moreover, the outer wall surface of the contact portion 6 and the outer wall surface of the reaction component 4 are not in the same plane, but are arranged at a certain angle, which increases the contact area, provides a larger space for heating, and enables a more efficient reaction.

[0033] The above embodiments are only for illustrating the technical concept and features of the present invention, and their purpose is to enable people familiar with this technology to understand the content of the present invention and implement it accordingly, and they are not intended to limit the scope of protection of the present invention. For those skilled in the art, it is obvious that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic characteristics of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes that fall within the meaning and scope of the equivalent elements of the claims are included in the present invention.

Claims

1. A detection reaction device, characterized in that: include: A detection component (1), wherein the detection component (1) is an internal hollow structure, and a partition layer (2) is provided therein, dividing the interior of the detection component (1) into a detection area (11) and a drying area (12), wherein the detection area (11) has a built-in detection test piece (3), and the drying area (12) has a built-in desiccant, and the partition layer (2) is provided with a through hole (21) to connect the drying area (12) and the detection area (11); A reaction component (4) is detachably connected to the detection component (1), and a reaction chamber (41) is provided inside the reaction component (4) for containing a diluent; Wherein, when the detection component (1) and the reaction component (4) are installed, a sealing film is provided at one adjacent end for sealing. When the detection component (1) is inserted into the reaction component (4), the diluent flows into the detection area (11) and contacts the detection test piece (3) for detection.

2. A detection reaction device according to claim 1, characterized in that: The detection assembly (1) comprises a partition (13) and a detection portion (14); the partition (13) and the detection portion (14) are detachably connected; the detection test piece (3) is provided in the detection portion (14); a partition plate (15) is provided in the partition (13); when the partition (13) is inserted into the reaction assembly (4), the partition plate (15) divides the reaction chamber (41) into a plurality of reaction spaces (42).

3. A detection reaction device according to claim 2, characterized in that: There are multiple detection test strips (3), all of which are located in the detection area (11), and the multiple detection test strips (3) correspond one-to-one to the multiple reaction spaces (42) for detecting different items.

4. A detection reaction device according to claim 3, characterized in that: The separation layer (2) includes a first separation plate (22) and a second separation plate (23). The second separation plate (23) is arranged along the axial direction of the detection component (1) and is bent multiple times. The bending forms a bending area (24) in the reaction chamber (41) to provide an installation position for the detection test piece (3). The first separation portion (13) is arranged perpendicular to the second separation plate and is sealed to one end of the second separation plate and the inner wall of the detection component (1).

5. A detection reaction device according to claim 2, characterized in that: The through holes (21) are arranged through the first partition plate (22) and are distributed in a circumferential array.

6. A detection reaction device according to claim 2, characterized in that: The detection strip (3) is arranged axially along the detection component (1), and one end extends over the first partition plate (22), so that the height of the end of the detection strip (3) close to the reaction component (4) is lower than the height of the partition plate (15).

7. The detection reaction device according to claim 1, characterized in that: A puncture body (5) is provided on the bottom surface of the reaction component (4), and the puncture body (5) has a tip portion (51) and faces the detection component (1).

8. The detection reaction device according to claim 1, characterized in that: A contact portion (6) is provided at one end of the reaction component (4) away from the detection component (1) along the outer wall contour of the reaction component (4), and the outer wall of the contact portion (6) is arranged at an angle to the outer wall of the reaction component (4).

9. The detection reaction device according to claim 1, characterized in that: The detection reaction device is a transparent structure as a whole, and changes in the detection test piece (3) can be observed.

10. A detection reaction method, applied to a detection reaction device according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1: dividing the reaction space (42): inserting the partition (13) into the reaction chamber (41), piercing the sealing film with the puncturing body (5), and dividing the reaction chamber (41) into a plurality of reaction spaces (42) with the partition plate (15); S2: adding different dilutions into different reaction spaces (42); S3: dropping the solution to be tested into the reaction space (42) and heating it; S4: Absorption of the test strip (3): After the reaction in step S3 is completed, the detection part (14) is inserted into the partition (13) to allow the diluent to flow into the test strip (3); S5: Observe the reaction results of the test strip (3) and judge the infectious disease detection results according to the preset interpretation standards.

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