Bone age detection device and method
By using ultrasound technology to obtain images of epiphysis and ossification centers and combining them with a standardized database to evaluate bone age, the radioactive hazards and human errors of traditional X-ray examinations are solved, and radiation-free, fast and accurate bone age detection is achieved.
Patent Information
- Application Number
- CN202511198730.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-08-25
- Publication Date
- 2025-10-10
AI Technical Summary
Traditional bone age detection methods rely on X-ray examinations, which are subject to radiation hazards, large human errors, long detection cycles, and low standardization, affecting the accuracy and reliability of the detection.
Ultrasound technology was used to obtain images of the epiphysis and ossification center of the distal radius and ulna at the wrist through a solid sound-conducting pad bracelet and an ultrasound probe. The epiphyseal ossification rate was calculated in combination with an ultrasound image processing system and evaluated using a standardized database.
It achieves radiation-free, fast and accurate bone age assessment, reduces detection risks, improves detection accuracy and convenience, and ensures the objectivity and repeatability of detection results.
Smart Images
Figure CN120753694A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of bone age detection, and in particular to a bone age detection device and method. Background Art
[0002] Bone age is an important method for assessing the biological age of adolescents and children, and is widely used in clinical medicine, forensic medicine, and sports medicine. Traditional bone age assessment methods mainly include the Greulich-Pyle (GP) atlas method, the Tanner-Whitehouse (TW2) scoring method, and the CHN method, which is suitable for the skeletal development of the Chinese hand. These methods generally require X-rays of the hand, in which doctors observe the development of ossification centers in the metacarpal phalanges, carpal bones, and the lower end of the radius and ulna to predict bone age. However, these methods have several significant drawbacks: First, X-rays are radioactive, posing a potential health hazard to children and are not suitable for frequent testing; second, bone age assessment results are significantly influenced by subjective factors and lack high accuracy; finally, the inherent "grade ambiguity" problem under existing standards makes the classification of skeletal development grades less accurate. Summary of the Invention
[0003] The purpose of this application is to provide a bone age detection device and method that can avoid the use of radioactive X-rays while ensuring the objectivity and accuracy of bone age detection.
[0004] To achieve the above objectives, this application provides the following solutions:
[0005] In a first aspect, the present application provides a bone age detection device, which includes: a solid sound-conducting pad bracelet, an ultrasound function module, and a forearm fixation and position adjustment module;
[0006] Solid sound conductive pads are respectively provided on both sides of the solid sound conductive pad bracelet;
[0007] The solid sound conductive pad bracelet is used to be worn on the wrist; the solid sound conductive pads on both sides of the solid sound conductive pad bracelet are respectively aligned with the distal end of the radius and the distal end of the ulna of the wrist;
[0008] The ultrasound function module includes: an ultrasound image processing system and two ultrasound probes;
[0009] The ultrasound probe is used to acquire ultrasound data; the ultrasound data includes: images of the epiphysis and ossification center of the distal radius and ulna of the wrist; when acquiring ultrasound data, the two ultrasound probes are respectively aimed at the solid sound conductive pads on both sides of the solid sound conductive pad bracelet;
[0010] The forearm fixing and position adjustment module includes: a fixed base, a lifting mechanism and a rotating mechanism;
[0011] The lifting mechanism is used to adjust the height of the fixed base according to the usage scenario; the rotating mechanism is used to achieve multi-angle adjustment of the ultrasound probe;
[0012] The ultrasonic image processing system is used for:
[0013] Obtaining the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis according to the ultrasound data;
[0014] Calculating the ultrasonic epiphyseal ossification rate according to the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis;
[0015] The ultrasonic epiphyseal ossification rate is compared with standard characteristic data to obtain the age corresponding to the ultrasonic epiphyseal ossification rate.
[0016] Optionally, the solid sound-conducting pad is arc-shaped, with a plastic limit frame at the edge and a prefabricated solid sound-conducting gel inside;
[0017] Distilled water is also provided inside the solid sound-conducting pad.
[0018] Optionally, the solid sound-conducting pad bracelet is an elastic latex bracelet;
[0019] There are openings on both sides of the solid sound conductive pad bracelet, and the openings are used to install the solid sound conductive pad.
[0020] Optionally, the ultrasound probe is a broadband ultrasound probe with a center frequency of 10 MHz.
[0021] Optionally, the ultrasound function module further includes: an ultrasound signal acquisition system;
[0022] The ultrasonic signal acquisition system adopts a 32-bit digital signal processor with a sampling frequency of 100 MHz; the ultrasonic signal acquisition system is used to acquire the ultrasonic echo data of the ultrasonic probe in real time.
[0023] Optionally, the bone age detection device further comprises: a standardized database, a controller and a display;
[0024] The standardized database contains standard feature data of several epiphyseal types.
[0025] Optionally, a positioning mark is provided on the solid sound conductive pad bracelet; the positioning mark is used to mark the position of the solid sound conductive pad; the bone age detection device further includes: a visual recognition module;
[0026] The visual recognition module includes a set of cameras facing the center of the ultrasound probe;
[0027] The camera is used to identify the positioning mark on the solid sound conductive pad bracelet.
[0028] Optionally, the fixed base is made of aluminum alloy material, and the surface is treated by anti-skid treatment.
[0029] The lifting mechanism is driven by a pneumatic cylinder.
[0030] The rotating mechanism adopts a precision gear set.
[0031] The second aspect of the application provides a bone age detection method of the bone age detection device.
[0032] Obtaining ultrasonic data; the ultrasonic data includes: the epiphysis and ossification center image of the distal radius and ulna of the wrist;
[0033] According to the ultrasonic data, the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis are obtained;
[0034] According to the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis, the ultrasonic epiphyseal ossification rate is calculated;
[0035] Comparing the ultrasonic epiphyseal ossification rate with the standard data, the age corresponding to the ultrasonic epiphyseal ossification rate is obtained.
[0036] Optionally, after comparing the ultrasonic epiphyseal ossification rate with the standard data, the age corresponding to the ultrasonic epiphyseal ossification rate is obtained, further comprising:
[0037] Comparing the age corresponding to the ultrasonic epiphyseal ossification rate with the actual age, it is judged whether the development is advanced or delayed.
[0038] According to the specific embodiments provided by the application, the following technical effects are disclosed:
[0039] The application provides a bone age detection device and method, which comprises a solid sound guide pad bracelet, an ultrasonic function module, a forearm fixing and position adjusting module, solid sound guide pads are arranged on the two sides of the solid sound guide pad bracelet respectively, the solid sound guide pad bracelet is used for being worn on the wrist, the solid sound guide pads on the two sides of the solid sound guide pad bracelet are respectively aligned with the distal end of the radius and the distal end of the ulna of the wrist, the ultrasonic function module comprises an ultrasonic image processing system and two ultrasonic probes, the ultrasonic probes are used for acquiring ultrasonic data, the ultrasonic data comprises epiphysis and ossification center images of the distal end of the radius and the distal end of the ulna of the wrist, when the ultrasonic data is acquired, the two ultrasonic probes are respectively aligned with the solid sound guide pads on the two sides of the solid sound guide pad bracelet, the forearm fixing and position adjusting module comprises a fixing base, a lifting mechanism and a rotating mechanism, the lifting mechanism is used for adjusting the height of the fixing base according to a use scene, the rotating mechanism is used for realizing multi-angle adjustment of the ultrasonic probes, the ultrasonic image processing system is used for acquiring a maximum value of an ossification center transverse diameter and a maximum value of an epiphysis transverse diameter according to the ultrasonic data, calculating an ultrasonic epiphysis ossification rate according to the maximum value of the ossification center transverse diameter and the maximum value of the epiphysis transverse diameter, and comparing the ultrasonic epiphysis ossification rate with standard characteristic data to obtain an age corresponding to the ultrasonic epiphysis ossification rate. The bone age is detected by the ultrasonic mode, so that the X-ray with radioactivity is avoided, and the objectivity and accuracy of the bone age detection are ensured by comparing the calculated ultrasonic epiphysis ossification rate with the standard characteristic data to obtain the corresponding age. BRIEF DESCRIPTION OF DRAWINGS
[0040] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, hereinafter, the drawings needed to be used in the embodiments will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.
[0041] Figure 1 A flowchart of a bone age detection method provided by an embodiment of the present application is shown. DETAILED DESCRIPTION
[0042] Hereinafter, the technical solutions in the embodiments of the present application will be described clearly and completely with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only some embodiments of the present application, but not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.
[0043] The ultrasound technology determines the bone age of children by measuring the thickness of the femoral head cartilage, but its sensitivity is low, the quality of the obtained ultrasound image is poor, and the detection model output result is inaccurate. At the same time, the ultrasound detection technology has problems such as non-uniform standards, differences in operation methods and system parameters in bone age determination.
[0044] The prior art has the following disadvantages:
[0045] 1. The traditional bone age evaluation method mainly relies on X-ray examination, which has potential harm to the health of children and is not suitable for frequent detection, affecting the accuracy and reliability of bone age evaluation.
[0046] 2. The current ultrasound bone age detection system lacks standardization, and lacks unified evaluation standards and operation methods, affecting the accuracy and repeatability of the detection results.
[0047] 3. The existing technology has problems such as large human error, long detection period, and high dependence on operators in bone age determination, which reduces the accuracy and robustness of bone age detection.
[0048] 4. The existing ultrasound bone age detection system still needs to be improved in image quality and feature extraction, and it is difficult to accurately reflect the bone development status, affecting the accuracy and efficiency of bone age evaluation.
[0049] Therefore, it is urgent to develop a more accurate, reliable and convenient bone age detection method to solve the problems in the prior art. An ideal bone age detection system should be able to provide non-radiation, fast and accurate bone age evaluation results, and have strong operation convenience and standardization. Such a system should be able to overcome the defects of large human error, long detection period, and high dependence on operators in the prior art, and improve the accuracy and robustness of bone age detection. The existing bone age detection system has problems such as large radiation, inconvenient operation, low standardization and insufficient detection accuracy. Therefore, in order to solve the above problems, the present application provides a bone age detection device and method.
[0050] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the present application will be further described in detail below in combination with the drawings and specific embodiments.
[0051] Embodiment one:
[0052] In one exemplary embodiment, a bone age detection device is provided, which comprises a solid acoustic pad bracelet, an ultrasonic function module, a forearm fixing and position adjusting module.
[0053] The solid sound conductive pad bracelet is used to reduce the amount of liquid coupling gel used, improve inspection efficiency and reduce the difficulty of equipment maintenance. The whole bracelet is a latex bracelet with a certain degree of elasticity and made of skin-friendly material. The bracelet is about 6CM wide and has two openings at corresponding positions for installing solid sound conductive pads.
[0054] Solid sound conductive pads are respectively provided on both sides of the solid sound conductive pad bracelet.
[0055] The solid acoustic pad is a replaceable design. Each piece measures 5cm by 4cm and is curved to fit the wrist's natural curvature. The edge is a plastic retaining frame, and the interior contains a prefabricated solid acoustic gel. During production, it is individually packaged and filled with a suitable amount of distilled water to ensure the gel is moist and full. To use, remove the outer packaging of the solid acoustic pad, remove the pad, and insert it into the pre-set gap in the wristband opening using the retaining frame's snap-in position to complete assembly.
[0056] The solid sound conductive pad bracelet is used to be worn on the wrist; the solid sound conductive pads on both sides of the solid sound conductive pad bracelet are respectively aligned with the distal end of the radius and the distal end of the ulna of the wrist.
[0057] When using a solid sound conductive pad bracelet, water should be sprayed on both sides of the wrist to couple the skin with the sound conductive pad. The child being tested should wear the solid sound conductive pad bracelet on the wrist, with the solid sound conductive pads on both sides aligned with the distal radius and distal ulna of the wrist respectively. The positioning marks on the bracelet should be aligned with the sides of the thumb and little finger at this time.
[0058] The ultrasound function module includes: an ultrasound image processing system and two ultrasound probes.
[0059] The ultrasonic probe is used to obtain ultrasonic data; the ultrasonic data includes: images of the epiphysis and ossification center of the distal radius and ulna of the wrist; when obtaining ultrasonic data, the two ultrasonic probes are respectively aimed at the solid sound conductive pads on both sides of the solid sound conductive pad bracelet.
[0060] The ultrasound probe uses a broadband ultrasound probe with a center frequency of 10 MHz, which can simultaneously obtain images of the epiphysis and ossification center of the distal radius and ulna in the wrist.
[0061] The ultrasound function module also includes an ultrasound signal acquisition system, which uses a 32-bit digital signal processor with a sampling frequency of 100MHz and is capable of collecting ultrasound echo data in real time. The ultrasound image processing system processes the collected echo data using a deep learning algorithm, including epiphyseal contour extraction, epiphyseal feature analysis, and bone age assessment.
[0062] During manual operation, there are cases with and without auxiliary measurement functions.
[0063] During the manual inspection without auxiliary measurement, the operator aligns the ultrasound probes on both sides with the solid acoustic pads on the solid acoustic pad bracelet, adjusts the position of the ultrasound probes to obtain images of the epiphysis and ossification center of the distal radius and distal ulna at the wrist, freezes the image and saves it. In subsequent statistics, the physician can perform manual measurements and calculations to obtain the maximum transverse diameters of the epiphysis and ossification center, and calculate them by substituting them into the formula.
[0064] During the manual inspection process of the preset auxiliary measurement, after the operator adjusts the position of the ultrasound probe, the image-assisted recognition can use different colors to mark the unossified area of the epiphysis and the ossification center respectively. The operator can observe the image during the adjustment process and freeze it after obtaining the ideal image. After freezing, the auxiliary measurement function will measure the maximum transverse diameter of the marked color block area respectively, obtain the maximum transverse diameter of the epiphysis and ossification center, and automatically enter it into the formula to calculate the OR value.
[0065] After the automatic scanning function mentioned in the article is implemented, the ultrasound probe can determine the position of the solid sound-conducting pad based on the positioning system and make preliminary placement. It can also fine-tune the position of the ultrasound probe based on the image provided by the auxiliary recognition function to obtain the best image. The subsequent measurement and calculation functions are the same as the previous solution.
[0066] The forearm fixing and position adjustment module includes: a fixed base, a lifting mechanism, and a rotating mechanism. The lifting mechanism is used to adjust the height of the fixed base according to the usage scenario; the rotating mechanism is used to achieve multi-angle adjustment of the ultrasound probe.
[0067] The fixed base is constructed of aluminum alloy with a non-slip finish. The lifting mechanism is driven by a pneumatic cylinder, allowing the base's height to be adjusted to suit different usage scenarios. The rotation mechanism utilizes a precision gear train, enabling the ultrasound probe to be adjusted at multiple angles.
[0068] The bone age detection device further comprises: a standardized database, a controller and a display; the standardized database contains standard feature data of several epiphyseal types.
[0069] The controller uses an industrial-grade embedded computer equipped with an Intel Core i7 processor, 16GB of RAM, and a 512GB solid-state drive. It incorporates multiple bone age assessment algorithms, including one based on diameter ratio and one based on deep learning. The controller communicates with the display via a wireless network, enabling remote control and real-time data transmission.
[0070] The display features a 10.1-inch IPS high-definition display with a resolution of 1920×1200 and supports multi-viewing angles. The display incorporates multiple image processing algorithms that enhance and process ultrasound images in real time, visually displaying the development of epiphyses and ossification centers.
[0071] This standardized database includes standard feature data for a variety of common epiphyseal types, which is used to evaluate the accuracy of newly detected data. By comparing the detected data with the standard data, the ultrasonic epiphyseal ossification rate (OR) is automatically calculated and combined with sex hormone levels to generate a detailed bone age assessment report.
[0072] The working process of the device is as follows: first, the height and rotation angle of the fixed base are adjusted through the forearm fixation and position adjustment module, and the ultrasound probe is aimed at the detection part; then the controller starts the ultrasound signal acquisition system to collect ultrasound echo data; then the ultrasound image processing system processes the echo data to extract the epiphyseal contour and features; finally, the controller calculates the maximum diameter ratio OR of the epiphysis to the ossification center based on the processing results, and compares it with the data in the standard database to generate a bone age assessment report.
[0073] OR = maximum transverse diameter of ossification center / maximum transverse diameter of epiphysis × 100%. Compare with the GP atlas method of radiological imaging. Based on the comparison of OR values, the age corresponding to the OR value can be obtained, and then compared with the actual age to analyze whether the child is developmentally advanced or delayed.
[0074] Since there is currently no bone age measurement atlas specifically used for ultrasound, this embodiment draws on the GP method of X-ray bone age measurement based on the type and nature of the collected images. The bone age OR value of the age group can be obtained based on the standard bone age images of different age groups in the GP method. By comparing with the OR value of the standard atlas, if the age corresponding to the ultrasound bone age OR value of the child being tested is greater than the actual age, the possibility of early or advanced development is considered; if it is younger than the actual age, the possibility of developmental delay or maldevelopment is considered.
[0075] The ultrasound probe is connected to a movable mechanism, and the probe can be manually or electrically adjusted to move forward and backward, up and down, and inward and outward. The monitor can be used to observe whether a clear image of the epiphysis and ossification center is obtained. After the big data model is trained and mature, the software can control the probe to complete the positioning and search for the epiphysis and ossification center. Two ultrasound probes are set up at this position, which are responsible for the detection of the left and right epiphysis and ossification centers respectively, and can obtain the corresponding ultrasound data at the same time. One side of the probe is responsible for aiming at the epiphysis area of the distal radius of the wrist to obtain the maximum transverse diameter of the epiphysis and the maximum transverse diameter of the ossification center in the epiphysis. The other side of the probe is aimed at the epiphysis area of the short ulnar element of the wrist to obtain the maximum transverse diameter of the epiphysis on this side and the maximum transverse diameter of the ossification center in the epiphysis.
[0076] There are several prerequisites for automated detection:
[0077] The AI function for assisting in identifying images is mature: the first step is to enable the AI to accurately find the location of the epiphysis through learning from a large number of images, and to identify the ossification center and the unossified epiphyseal cartilage region according to the echo changes, and to distinguish them using different colors; the second step is to enable the AI to learn to make correct maximum transverse diameter measurements, according to the results of the first step of learning, to make transverse diameter measurements on the color blocks representing the ossification center and the epiphysis; the third step is to perform formula substitution and calculate the OR value.
[0078] The probe adjustment module is changed from manual mechanical adjustment to electric adjustment, and the mechanical link on both sides of the probe can control the probe to move up and down and back and forth, so that the probe can adjust the distance up and down and far and near with the wrist sound guide pad bracelet, and at the same time, the probe and the mechanical link are movable mechanisms, and with the up and down movement of the mechanical link, the probe can adjust the examination angle on the basis of closely adhering to the solid sound guide pad, and effectively scan the image.
[0079] Increase the positioning system: add a visual recognition module on the top of the device, mainly a set of cameras facing the center of the probe, used to identify the positioning mark on the bracelet. When in use, the child being examined extends his forearm into the device examination slot and holds the front handle, the camera shoots downward to capture the position of the forearm, and according to the degree of coincidence between the position of the forearm and the edge of the preset examination position, the arm is adjusted forward and backward through the handle. When the position of the forearm coincides with the edge in the screen to a high degree, the edge turns green, and the image collection can begin.
[0080] Compared with the prior art, the embodiment provides an ultrasonic system that can be used for rapid detection of the bone age of adolescents, and has the following beneficial effects:
[0081] 1. The embodiment acquires the epiphysis and ossification center images of the distal radius and ulna of the wrist through ultrasonic waves, combines the maximum diameter D of the connection point of the epiphysis and the diaphysis to the distal end of the epiphysis and the maximum diameter d of the two ends of the ossification center, and calculates the maximum diameter ratio OR of the epiphysis and the ossification center, so as to accurately evaluate the bone age development of adolescents, overcome the problems of large human error and long detection period in traditional X-ray film examination, and improve the accuracy and reliability of bone age detection.
[0082] 2. The embodiment uses ultrasonic technology to replace traditional X-ray film examination, avoids the potential harm of radioactivity to children's health, reduces the detection risk, is suitable for frequent detection, and improves the accuracy and reliability of bone age evaluation.
[0083] 3. The ultrasonic bone age detection system of the embodiment is composed of an ultrasonic function module, a forearm fixing and position adjustment module, a controller and a display, and can realize convenient mobile detection, so that users can perform detection without going to the hospital site, greatly improving the convenience of detection and reducing the application cost.
[0084] 4. The embodiment can guide the development of auxiliary treatment by standardizing the OR value evaluation standard combined with sex hormone levels, improve the standardization of bone age detection, and ensure the accuracy and repeatability of the detection results.
[0085] 5. The embodiment can intuitively present the development status of epiphysis and ossification center through ultrasound image, and comprehensively reflect the development status of adolescent skeleton by combining with the calculation of OR value, thereby improving the accuracy and efficiency of bone age evaluation.
[0086] Embodiment two:
[0087] In an exemplary embodiment, as shown in Figure 1 A bone age detection method of the bone age detection device is provided, which comprises:
[0088] S1, acquiring ultrasonic data; the ultrasonic data includes: epiphysis and ossification center images of the distal radius and ulna of the wrist.
[0089] S2, obtaining the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis according to the ultrasonic data.
[0090] S3, calculating the ultrasonic epiphyseal ossification rate according to the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis.
[0091] S4, comparing the ultrasonic epiphyseal ossification rate with the standard data to obtain the age corresponding to the ultrasonic epiphyseal ossification rate.
[0092] After comparing the ultrasonic epiphyseal ossification rate with the standard data to obtain the age corresponding to the ultrasonic epiphyseal ossification rate, the method further comprises:
[0093] Comparing the age corresponding to the ultrasonic epiphyseal ossification rate with the actual age to determine whether the development is advanced or delayed.
[0094] Embodiment three:
[0095] The ultrasonic probe in the ultrasonic function module of the bone age detection device provided in the embodiment is a wideband ultrasonic probe with a center frequency of 10 MHz, which can simultaneously obtain epiphysis and ossification center images of the distal radius and ulna of the wrist. The ultrasonic signal acquisition system adopts a 32-bit digital signal processor with a sampling frequency of 100 MHz, which can collect ultrasonic echo data in real time. The ultrasonic image processing system processes the collected echo data based on a deep learning algorithm, including epiphysis contour extraction, epiphysis feature analysis and bone age evaluation.
[0096] The fixing base of the forearm fixing and position adjusting module is made of aluminum alloy material and has an anti-slip surface. The lifting mechanism is driven by a pneumatic cylinder and can adjust the height of the fixing base according to different use scenarios, from 50 cm to 80 cm. The rotating mechanism adopts a precision gear set and can realize multi-angle adjustment of the ultrasonic probe within a range of 0° to 90°.
[0097] The controller is an industrial-grade embedded computer equipped with an Intel Core i7-8700 processor, 16 GB of memory, and a 512 GB solid state drive. The controller has multiple bone age assessment algorithms built-in, including a method based on the ratio of diameters and a method based on deep learning. The controller communicates with the display through a wireless network, enabling remote control and real-time data transmission.
[0098] The display uses a 10.1-inch IPS high-definition display with a resolution of 1920x1200 and supports multi-view display. The display has multiple image processing algorithms built-in, which can enhance and process ultrasonic images in real time, and intuitively present the development status of epiphyses and ossification centers.
[0099] The system also includes a standardized database that contains standard feature data for common epiphysis types, which is used to assess the accuracy of new detection data. The system automatically calculates the maximum diameter ratio OR of epiphyses and ossification centers by comparing the detection data with the standard data, and generates a detailed bone age assessment report in combination with sex hormone levels.
[0100] The workflow of the system is as follows: First, adjust the height and rotation angle of the fixing base through the forearm fixing and position adjusting module, and align the ultrasonic probe with the detection site; then the controller starts the ultrasonic signal acquisition system to collect ultrasonic echo data; then the ultrasonic image processing system processes the echo data to extract the epiphysis contour and features; finally, the controller calculates the maximum diameter ratio OR of the epiphysis and the ossification center according to the processing result, and compares it with the data in the standard database to generate a bone age assessment report.
[0101] Example Four:
[0102] The ultrasonic probe in the ultrasonic function module of the ultrasonic bone age detection device provided in this embodiment is a wideband ultrasonic probe with a center frequency of 10 MHz, which can simultaneously obtain images of epiphyses and ossification centers of the distal radius and ulna of the wrist. The ultrasonic signal acquisition system uses a 32-bit digital signal processor with a sampling frequency of 100 MHz, which can collect ultrasonic echo data in real time. The ultrasonic image processing system processes the collected echo data based on deep learning algorithms, including epiphysis contour extraction, epiphysis feature analysis, and bone age assessment.
[0103] The fixed base of the forearm fixation and position adjustment module is made of aluminum alloy with a non-slip surface treatment. The lifting mechanism is driven by a pneumatic cylinder, allowing the fixed base to be adjusted in height from 40cm to 90cm to suit different usage scenarios. The rotation mechanism utilizes a precision gear set, enabling multi-angle adjustment of the ultrasound probe from 0° to 180°.
[0104] The controller uses an industrial-grade embedded computer equipped with an Intel Core i7-9700 processor, 16GB of RAM, and a 1TB solid-state drive. It incorporates multiple bone age assessment algorithms, including one based on diameter ratio and one based on deep learning. The controller communicates with the display via a wireless network, enabling remote control and real-time data transmission.
[0105] The display features a 10.1-inch IPS high-definition display with a resolution of 1920×1200 and supports multi-viewing angles. The display incorporates multiple image processing algorithms that enhance and process ultrasound images in real time, visually displaying the development of epiphyses and ossification centers.
[0106] The system also includes a standardized database containing standard feature data for various common epiphyseal types, which is used to evaluate the accuracy of newly detected data. By comparing the detected data with the standard data, the system automatically calculates the ratio (OR) of the maximum diameter of the epiphysis to the ossification center and, combined with sex hormone levels, generates a detailed bone age assessment report.
[0107] The system's workflow is as follows: first, the height and rotation angle of the fixed base are adjusted through the forearm fixation and position adjustment module, and the ultrasound probe is aligned with the detection part; then the controller starts the ultrasound signal acquisition system to collect ultrasound echo data; then the ultrasound image processing system processes the echo data to extract the epiphyseal contour and features; finally, the controller calculates the maximum diameter ratio (OR) of the epiphysis to the ossification center based on the processing results, and compares it with the data in the standard database to generate a bone age assessment report.
[0108] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data used for analysis, stored data, displayed data, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties, and the collection, use and processing of relevant data must comply with relevant regulations.
[0109] Those skilled in the art will understand that all or part of the processes in the above-mentioned embodiment methods can be implemented by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to memory, database or other media used in the embodiments provided in this application may include at least one of non-volatile and volatile memory. Non-volatile memory may include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory may include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM may be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM).
[0110] The databases involved in the various embodiments provided herein may include at least one of a relational database and a non-relational database. Non-relational databases may include, but are not limited to, distributed databases based on blockchains. The processors involved in the various embodiments provided herein may include, but are not limited to, general-purpose processors, central processing units, graphics processing units, digital signal processors, programmable logic units, data processing logic units based on quantum computing, and the like.
[0111] The technical features of the above embodiments can be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0112] This document uses specific examples to illustrate the principles and implementation methods of this application. The description of the above examples is only intended to help understand the method and core concept of this application. At the same time, for those skilled in the art, based on the concept of this application, there may be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting this application.
Claims
1. A bone age detection device, characterized in that: The bone age detection device includes: a solid sound-conducting pad bracelet, an ultrasound function module, and a forearm fixation and position adjustment module; Solid sound conductive pads are respectively provided on both sides of the solid sound conductive pad bracelet; The solid sound conductive pad bracelet is used to be worn on the wrist; the solid sound conductive pads on both sides of the solid sound conductive pad bracelet are respectively aligned with the distal end of the radius and the distal end of the ulna of the wrist; The ultrasound function module includes: an ultrasound image processing system and two ultrasound probes; The ultrasound probe is used to acquire ultrasound data; the ultrasound data includes: images of the epiphysis and ossification center of the distal radius and ulna of the wrist; when acquiring ultrasound data, the two ultrasound probes are respectively aimed at the solid sound conductive pads on both sides of the solid sound conductive pad bracelet; The forearm fixing and position adjustment module includes: a fixed base, a lifting mechanism and a rotating mechanism; The lifting mechanism is used to adjust the height of the fixed base according to the usage scenario; the rotating mechanism is used to achieve multi-angle adjustment of the ultrasound probe; The ultrasonic image processing system is used for: Obtaining the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis according to the ultrasound data; Calculating the ultrasonic epiphyseal ossification rate according to the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis; The ultrasonic epiphyseal ossification rate is compared with standard characteristic data to obtain the age corresponding to the ultrasonic epiphyseal ossification rate.
2. The bone age detection device according to claim 1, characterized in that: The solid sound-conducting pad is arc-shaped, with a plastic limit frame at the edge and a prefabricated solid sound-conducting gel inside; Distilled water is also provided inside the solid sound-conducting pad.
3. The bone age detection device according to claim 1, characterized in that The solid sound-conducting pad bracelet is an elastic latex bracelet; There are openings on both sides of the solid sound conductive pad bracelet, and the openings are used to install the solid sound conductive pad.
4. The bone age detection device according to claim 1, characterized in that: The ultrasonic probe is a broadband ultrasonic probe with a center frequency of 10 MHz.
5. The bone age detection device according to claim 1, characterized in that: The ultrasonic function module also includes: an ultrasonic signal acquisition system; The ultrasonic signal acquisition system adopts a 32-bit digital signal processor with a sampling frequency of 100 MHz; the ultrasonic signal acquisition system is used to acquire the ultrasonic echo data of the ultrasonic probe in real time.
6. The bone age detection device according to claim 1, characterized in that: The bone age detection device also includes: a standardized database, a controller and a display; The standardized database contains standard feature data of several epiphyseal types.
7. The bone age detection device according to claim 1, characterized in that: The solid sound conductive pad bracelet is provided with a positioning mark; the positioning mark is used to mark the position of the solid sound conductive pad; the bone age detection device further includes: a visual recognition module; The visual recognition module includes a set of cameras facing the center of the ultrasound probe; The camera is used to identify the positioning mark on the solid sound conductive pad bracelet.
8. The bone age detection device according to claim 1, characterized in that: The fixed base is made of aluminum alloy and the surface is anti-slip treated; The lifting mechanism is driven by a pneumatic cylinder; The rotating mechanism adopts a precision gear set.
9. A bone age detection method according to the bone age detection device of claim 1, characterized in that: The bone age detection method comprises: Acquiring ultrasound data; the ultrasound data includes: images of the epiphysis and ossification center of the distal radius and ulna of the wrist; Obtaining the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis according to the ultrasound data; Calculating the ultrasonic epiphyseal ossification rate according to the maximum transverse diameter of the ossification center and the maximum transverse diameter of the epiphysis; The ultrasonic epiphyseal ossification rate is compared with standard data to obtain the age corresponding to the ultrasonic epiphyseal ossification rate.
10. The bone age detection method according to claim 9, characterized in that: After comparing the ultrasonic epiphyseal ossification rate with standard data to obtain the age corresponding to the ultrasonic epiphyseal ossification rate, the method further includes: The age corresponding to the ultrasonic epiphyseal ossification rate is compared with the actual age to determine whether the development is advanced or delayed.