Intelligent positioning medicine-carrying capsule

Abstract

The intelligent positioning medicine carrying capsule comprises a medicine bin, the medicine bin is connected with a control bin, and a control assembly and a driving assembly are arranged in the control bin; the control assembly can receive an external control signal and can control the driving assembly to drive the medicine bin to be separated from the control bin. The device has the beneficial effects that the driving assembly can be controlled through the control assembly, the medicine bin and the control bin are separated through the driving assembly, medicine is dissolved at a specific position, and the situation that medicine is absorbed in advance is avoided; the position of the control assembly is monitored through the external positioner, so that the position of the medicine bag is judged; the control assembly can receive an instruction issued by an external positioner, so that separation of the medicine bin and the control bin is finally achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of medicine-carrying capsules, in particular to an intelligent positioning medicine-carrying capsule. Background Art

[0002] Traditional oral formulations release drugs through passive diffusion in the gastrointestinal tract, leading to substantial drug degradation or premature absorption before reaching the lesion, resulting in decreased efficacy and increased systemic toxicity. In recent years, diseases such as inflammatory bowel disease (IBD), localized tumors, and Helicobacter pylori infection have created an urgent need for targeted, quantitative, and timed drug delivery.

[0003] To this end, the inventors designed a device that can actively release drugs at specific locations. Summary of the Invention

[0004] The purpose of this section is to summarize some aspects of the embodiments of the present invention and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the abstract and title of this application to avoid obscuring the purpose of this section, the abstract and the title of the invention, and such simplifications or omissions should not be used to limit the scope of the present invention.

[0005] In view of the above problems or problems existing in the prior art, the present invention is proposed.

[0006] Therefore, the purpose of the present invention is to provide an intelligent positioning drug-loaded capsule, which can actively release the drug compartment at a specific position to achieve precise treatment and avoid the premature absorption of drug efficacy.

[0007] In order to solve the above technical problems, the present invention provides the following technical solutions: an intelligent positioning drug-loaded capsule, which includes a drug chamber, which is connected to a control chamber, and a control component and a drive component are provided in the control chamber; the control component can receive an external control signal, and the control component can control the drive component to drive the drug chamber out of the control chamber.

[0008] As a preferred solution of the intelligent positioning medicine-carrying capsule of the present invention, an isolation piece is further provided in the control chamber, and the isolation piece can isolate the medicine chamber.

[0009] As a preferred solution of the intelligent positioning medicine-loaded capsule of the present invention, the driving component can drive the medicine chamber through the isolation piece, and the isolation piece can be deformed under the driving of the driving component.

[0010] As a preferred solution of the intelligent positioning drug-loaded capsule of the present invention, the isolating member is made of a flexible material, can isolate and seal the control chamber, and can follow the expansion and contraction deformation of the driving assembly.

[0011] As a preferred solution of the intelligent positioning medicine-loaded capsule of the present invention, the control chamber includes an upper control chamber and a lower control chamber; the control component is arranged in the lower control chamber; and the drive component is arranged in the upper control chamber.

[0012] As a preferred solution for the intelligent positioning of the drug-loaded capsule of the present invention, the driving component includes a temperature control unit and a driving component; the driving component is arranged on the periphery of the temperature control unit, the temperature control unit can adjust the temperature of the driving component, the driving component can perform telescopic movement at a certain temperature, and the driving component separates the drug chamber from the control chamber.

[0013] As a preferred solution of the intelligent positioning medicine-carrying capsule of the present invention, the temperature control unit includes a heating module, which can heat the driving component and has a certain flexibility.

[0014] As a preferred solution for the intelligent positioning of the drug-loaded capsule of the present invention, the driving component includes an elastic member, the temperature control unit heats the elastic member, the elastic member can push the drug chamber out of the control chamber, and the elastic member retracts into the control chamber after cooling down.

[0015] As a preferred solution of the intelligent positioning medicine-loaded capsule of the present invention, a sealing member is further provided on the control chamber, and the sealing member is provided between the control chamber and the medicine chamber.

[0016] As a preferred solution for the intelligent positioning of the drug-loaded capsule of the present invention, the control component includes a control module and a power control module; the power control module can supply power to the control module and the drive component, the external locator can perform position judgment and control signal transmission with the control module, and the control module can control the separation of the drug chamber and the control chamber.

[0017] The beneficial effects of the present invention are as follows: the present invention can control the driving component through the control component, utilize the driving component to separate the medicine chamber and the control chamber, so that the medicine dissolves at a specific position, thereby avoiding the situation where the drug effect is absorbed prematurely; the position of the control component is monitored by an external locator to determine the position of the medicine bag; the control component can receive instructions issued by the external locator, thereby ultimately realizing the separation of the medicine chamber and the control chamber. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. Those skilled in the art can also derive other drawings based on these drawings without inventive effort. Among them: Fig. 1 This is a front view of the intelligent positioning drug-loaded capsule.

[0019] Fig. 2An internal sectional view of the intelligent positioning drug-loaded capsule. DETAILED DESCRIPTION

[0020] In order to make the above objectives, features and advantages of the present application more obvious and easy to understand, the specific embodiments of the present application will be described in detail below with reference to the accompanying drawings.

[0021] In the following description, a large number of specific details are set forth in order to facilitate a thorough understanding of the present application, but the present application can also be implemented in other ways different from those described herein, and those skilled in the art can make similar generalizations without departing from the concept of the present application, therefore the present application is not limited to the specific embodiments disclosed below.

[0022] Secondly, the "one embodiment" or "embodiment" referred to herein means that a specific feature, structure or characteristic can be included in at least one implementation of the present application. "In one embodiment" appearing in different places in the specification does not mean the same embodiment, nor is it an embodiment that is separate or alternative to other embodiments. Embodiment 1

[0023] Reference Figs. 1-2 For the first embodiment of the present application, the embodiment provides an intelligent positioning drug-loaded capsule, which comprises a medicine bin 1 and a control bin 2 connected, and a control assembly 3 and a driving assembly 4 are arranged in the control bin 2, the control assembly 3 can control the driving assembly 4, and the driving assembly 4 can separate the medicine bin 1 from the control bin 2.

[0024] Specifically, it comprises a medicine bin 1, the medicine bin 1 is connected with a control bin 2, and a control assembly 3 and a driving assembly 4 are arranged in the control bin 2; the control assembly 3 can receive an external control signal, and the control assembly 3 can control the driving assembly 4 to drive the medicine bin 1 to separate from the control bin 2 to realize the release of the medicine inside.

[0025] It should be noted that the medicine bin 1 can contain powder, granules or liquid medicine.

[0026] It should be noted that a plurality of positioners can be placed at specific positions outside the human body, and the positioners contain positioning permanent magnets and Bluetooth master control units. When the capsule moves to the vicinity of the positioner with intestinal peristalsis, the range is about 50mm, the accuracy is about 5mm, the magnetic sensor in the control assembly 3 determines that the magnetic field strength reaches the threshold value, and then the external positioner is notified through the Bluetooth protocol.

[0027] Preferably, after receiving the information through the positioner, the doctor or the patient is prompted, and after confirmation, the release instruction of the medicine bin is returned to the capsule. The control assembly 3 starts the release program, and after the medicine bin releases successfully, the release completion instruction is sent to the positioner To sum up, the control assembly 3 can control the driving assembly 4, the driving assembly 4 can separate the medicine bin 1 from the control bin 2, and the medicine can be dissolved at a specific position, so that the situation that the medicine is absorbed in advance is avoided. Embodiment 2

[0028] With reference to Figs. 1-2 For the second embodiment of the application, in the previous embodiment, the intelligent positioning medicine-loading capsule comprises a medicine bin 1 and a control bin 2 connected, and a control assembly 3 and a driving assembly 4 are arranged in the control bin 2, the control assembly 3 can control the driving assembly 4, and the driving assembly 4 can separate the medicine bin 1 from the control bin 2.

[0029] Specifically, the intelligent positioning medicine-loading capsule comprises a medicine bin 1, the medicine bin 1 is connected with a control bin 2, and a control assembly 3 and a driving assembly 4 are arranged in the control bin 2; the control assembly 3 can receive an external control signal, and the control assembly 3 can control the driving assembly 4 to drive the medicine bin 1 to separate from the control bin 2 to release the medicine inside.

[0030] It should be noted that the medicine in the medicine bin 1 can be in the form of powder, granules or liquid.

[0031] It should be noted that a plurality of positioners can be placed at specific positions outside the human body, and the positioners contain positioning permanent magnets and Bluetooth master control units. When the capsule moves to the vicinity of the positioner along the intestinal tract, the magnetic sensor in the control assembly 3 determines that the magnetic field strength reaches a threshold value, and then notifies the external positioner through the Bluetooth protocol.

[0032] Preferably, after receiving the information through the positioner, the doctor or the patient is prompted, and after confirmation, the medicine bin release instruction is returned to the capsule. The control assembly 3 starts the release program, and after the medicine bin releases successfully, the release completion instruction is sent to the positioner. Further, the control bin 2 is further provided with a separation piece 5, and the separation piece 5 can isolate the medicine bin 1.

[0033] Preferably, the separation piece 5 is arranged in the control bin 2, so that the medicine in the medicine bin 1 cannot enter the control bin 2.

[0034] Further, the driving assembly 4 can drive the medicine bin 1 through the separation piece 5, and the separation piece 5 can be deformed under the driving of the driving assembly 4.

[0035] Further, the separation piece 5 is made of flexible material, the separation piece 5 can isolate and seal the control bin 2, and the separation piece 5 can stretch and deform along with the driving assembly 4.

[0036] Preferably, the isolation member 5 is made of a flexible material, such as a highly elastic silicone film, and of course other flexible materials can also be used; by setting the isolation member 5 to a flexible material, it is convenient for the driving component 42 to drive the medicine chamber 1 through the isolation member 5.

[0037] Preferably, the isolating member 5 has the ability to be elastically deformed, and has the function of isolating the liquid medicine and preventing the driving component 42 from being separated from the control chamber 2 .

[0038] Furthermore, the control compartment 2 includes an upper control compartment 21 and a lower control compartment 22 ; the control component 3 is disposed in the lower control compartment 22 ; and the drive component 4 is disposed in the upper control compartment 21 .

[0039] Furthermore, the driving assembly 4 includes a temperature control unit 41 and a driving component 42; the driving component 42 is arranged on the peripheral side of the temperature control unit 41, the temperature control unit 41 can adjust the temperature of the driving component 42, the driving component 42 can perform telescopic movement at a certain temperature, and the driving component 42 separates the medicine chamber 1 from the control chamber 2.

[0040] Furthermore, the temperature control unit 41 includes a heating module 411 , which can heat the driving component 42 , and the heating module 411 has a certain degree of flexibility.

[0041] Preferably, the heating module 411 can adopt an FPC flexible heating module. Of course, the heating module 411 can also adopt existing technology.

[0042] Furthermore, the driving component 42 includes an elastic member 421 . The temperature control unit 41 heats the elastic member 421 . The elastic member 421 can push the medicine chamber 1 out of the control chamber 2 , and the elastic member 421 retracts into the control chamber 2 after cooling down.

[0043] Preferably, the elastic member 421 includes a temperature control spring made of memory alloy. , wire diameter 1mm, deformation temperature 50 °C; the elastic member 421 will retract to its initial state after the temperature control unit 41 stops heating.

[0044] Preferably, the elastic member 421 may be a nickel-titanium alloy spring.

[0045] Preferably, the heating module 411 heats the elastic member 421, and the elastic member 421 begins to deform after being heated to 50 degrees, and can drive the medicine chamber 1 through the isolation member 5, so that the medicine chamber 1 is separated from the control chamber 2, thereby achieving the release of the medicine in the medicine chamber 1 at a specific position.

[0046] The control chamber 2 can be made of biocompatible materials such as PC, and the drug chamber 1 can be made of the same material, or a degradable material such as PLA polylactic acid can be used to improve safety.

[0047] Furthermore, a sealing member 6 is provided on the control chamber 2 , and the sealing member 6 is provided between the control chamber 2 and the medicine chamber 1 .

[0048] Furthermore, the control component 3 includes a control module 31 and a power control module 32; the power control module 32 can supply power to the control module 31 and the drive component 4, the external locator can perform position judgment and control signal transmission with the control module 31, and the control module 31 can control the separation of the medicine chamber 1 and the control chamber 2.

[0049] It should be noted that the control module 31 includes an integrated antenna + Bluetooth + magnetic switch; It should be noted that the capsule size is: ; Power control module 32: It is required to be able to run for about 8 hours and be able to run to the cecum; it can send out signals and be received by the signal device or contain metal and can be detected by the metal detector within a smaller range; it has a certain drug loading function, and the drug is in powder or liquid form, that is, the drug loading chamber is required to have good sealing performance; the drug loading capsule can be remotely controlled outside the body, and after reaching the specified position, the drug loading chamber can be released by the remote control to release the drug into the body; the drug loading chamber can realize on-demand drug loading, that is, the required drug can be loaded and swallowed immediately; the drug loading capsule can be detected by X-ray in the body.

[0050] Working principle: 1. In vitro magnetic positioning The patient places an external locator on the body surface where the capsule is to be released. The locator contains a permanent magnet and a Bluetooth main control unit. When the capsule moves with intestinal peristalsis to within approximately 50 mm of the locator, with an accuracy of approximately 5 mm, the magnetic sensor in control component 3 determines that the magnetic field strength has reached a threshold and notifies the external locator via Bluetooth.

[0051] 2. Release of medicine warehouse After receiving the capsule's command, the locator notifies the doctor or patient, who then confirms the command and sends the medicine chamber release command back to the capsule. The control component 3 initiates the release process, using the drive component 4 to separate the medicine chamber 1. Once the medicine chamber is released successfully, a release completion command is sent to the locator.

[0052] 3. Safety failure mode If no command is received within 24 hours, the capsule automatically enters "fail-safe" mode, the medicine chamber remains sealed, and the medicine is discharged with the feces; when the battery is undervoltage (<2.2 V), the MCU closes the release mechanism to prevent the capsule from being half-open.

[0053] In summary, the present invention can control the driving component 4 through the control component 3, and use the driving component 4 to separate the medicine chamber 1 and the control chamber 2, so that the medicine dissolves at a specific position, avoiding the situation where the drug effect is absorbed prematurely; the position of the control component 3 is monitored by an external locator to determine the position of the medicine bag; the control component 3 can receive instructions issued by the external locator, thereby finally realizing the separation of the medicine chamber 1 and the control chamber 2.

[0054] It is important to note that the construction and arrangement of the present application, as illustrated in various exemplary embodiments, are illustrative only. Although only a few embodiments are described in detail in this disclosure, those reading this disclosure will readily appreciate that numerous modifications are possible (e.g., variations in the size, dimensions, structure, shape, and proportions of various components, as well as parameter values ​​(e.g., temperature, pressure, etc.), mounting arrangements, use of materials, color, orientation, etc.) without materially departing from the novel teachings and advantages of the subject matter described herein. For example, components shown as integrally formed may be constructed from multiple parts or components, the positions of components may be inverted or otherwise altered, and the nature, number, or position of discrete components may be modified or changed. All such modifications are therefore intended to be encompassed within the scope of this invention. The order or sequence of any process or method steps may be altered or resequenced according to alternative embodiments. In the claims, any "means-plus-function" clause is intended to cover structures described herein that perform the recited function, and not only structural equivalents but also equivalent structures. Other substitutions, modifications, changes, and omissions may be made in the design, operating conditions, and arrangement of the exemplary embodiments without departing from the scope of this invention. Therefore, the invention is not limited to the specific embodiments, but extends to various modifications that still fall within the scope of the appended claims.

[0055] Additionally, in order to provide a concise description of exemplary embodiments, all features of an actual embodiment may not be described (i.e., those features that are not relevant to the best mode presently contemplated for carrying out the invention or those that are not relevant to implementing the invention).

[0056] It will be appreciated that in the development of any actual embodiment, as in any engineering or design project, numerous implementation-specific decisions may be made. Such a development effort may be complex and time-consuming, but will, for those of ordinary skill having the benefit of this disclosure, be a routine undertaking of design, fabrication, and production without undue experimentation.

[0057] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. An intelligent positioning drug-loaded capsule, characterized by: The invention comprises a medicine chamber (1), wherein the medicine chamber (1) is connected to a control chamber (2), and a control component (3) and a drive component (4) are arranged in the control chamber (2); the control component (3) can receive an external control signal, and the control component (3) can control the drive component (4) to drive the medicine chamber (1) to separate from the control chamber (2).

2. The smart positioning medicine-carrying capsule according to claim 1, characterized in that: An isolation member (5) is further provided in the control chamber (2), and the isolation member (5) can isolate the medicine chamber (1).

3. The smart positioning medicine-carrying capsule according to claim 2, characterized in that: The driving component (4) can drive the medicine chamber (1) via the isolating member (5), and the isolating member (5) can be deformed under the driving of the driving component (4).

4. The smart positioning medicine-carrying capsule according to claim 2, characterized in that: The isolating member (5) is made of a flexible material, and the isolating member (5) can isolate and seal the control compartment (2), and the isolating member (5) can follow the drive assembly (4) to expand and contract.

5. The smart positioning medicine-carrying capsule according to claim 1, characterized in that: The control chamber (2) comprises an upper control chamber (21) and a lower control chamber (22); the control component (3) is arranged in the lower control chamber (22); and the drive component (4) is arranged in the upper control chamber (21).

6. The smart positioning medicine-carrying capsule according to claim 1, characterized in that: The driving assembly (4) includes a temperature control unit (41) and a driving component (42); the driving component (42) is arranged on the peripheral side of the temperature control unit (41); the temperature control unit (41) can adjust the temperature of the driving component (42); the driving component (42) can perform telescopic movement at a certain temperature; and the driving component (42) separates the medicine chamber (1) from the control chamber (2).

7. The smart positioning medicine-carrying capsule according to claim 6, characterized in that: The temperature control unit (41) includes a heating module (411), and the heating module (411) can heat the driving component (42), and the heating module (411) has a certain degree of flexibility.

8. The smart positioning medicine-carrying capsule according to claim 6, characterized in that: The driving component (42) includes an elastic member (421). The temperature control unit (41) heats the elastic member (421). The elastic member (421) can push the medicine chamber (1) out of the control chamber (2), and the elastic member (421) retracts into the control chamber (2) after cooling down.

9. The smart positioning medicine-carrying capsule according to claim 1, characterized in that: The control chamber (2) is further provided with a sealing member (6), and the sealing member (6) is provided between the control chamber (2) and the medicine chamber (1).

10. The smart positioning medicine-carrying capsule according to any one of claims 1 to 9, characterized in that: The control component (3) includes a control module (31) and a power control module (32); the power control module (32) can supply power to the control module (31) and the drive component (4); the external positioner can perform position determination and control signal transmission with the control module (31); and the control module (31) can control the separation of the medicine chamber (1) and the control chamber (2).

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