Gravity settling sorting tower for folic acid metabolism detection and method thereof

Abstract

The invention relates to the technical field of gravity settling separation, in particular to a gravity settling separation tower for folic acid metabolism detection, which comprises a tower body, lifting mechanisms are arranged on two sides of the tower body, a second motor is fixedly arranged at the bottom of the center of the tower body, a supporting mechanism is arranged at the output end of the second motor in a transmission manner, and a conductive mechanism is mounted at the upper end of the supporting mechanism. Through the natural inclination design of the gravity precipitation tank, preliminary layering of blood can be realized under the action of gravity, meanwhile, the centrifugal layering function driven by a second motor is combined, the layering speed can be remarkably increased, the layering efficiency is improved, and the device is particularly suitable for a detection scene where a large number of samples need to be rapidly treated; and each precipitation disc can be independently subjected to layered operation, so that the treatment capacity of the equipment is greatly improved by virtue of the multi-disc design, layered treatment of a plurality of samples can be completed at the same time, the detection efficiency is remarkably improved, and the requirement of high-throughput detection is met.

Description

Technical Field

[0001] The present invention relates to the technical field of gravity sedimentation sorting, in particular to a gravity sedimentation sorting tower for folic acid metabolism detection and a method thereof. Background Art

[0002] Folate metabolism testing is crucial for medical diagnosis, nutritional assessment, and related disease research. Folic acid is an essential nutrient for the human body and is involved in numerous biochemical processes, such as DNA synthesis and repair, and amino acid metabolism. Abnormal folate metabolism is closely associated with the development and progression of numerous diseases, including anemia, cardiovascular disease, neurological disorders, and certain cancers. Therefore, accurate monitoring of folate metabolism is crucial for early diagnosis, treatment monitoring, and personalized medicine.

[0003] In folate metabolism testing, the processing of blood samples is a key step. Traditional blood processing methods usually involve centrifugation to separate plasma or serum, followed by subsequent biochemical analysis. However, these methods have some limitations. For example, centrifugation requires specialized equipment and strict operating conditions (such as centrifugation speed, time, etc.), otherwise it may cause cell components to rupture or incomplete stratification, thereby affecting the accuracy of the test results. In addition, mechanical stress may be introduced during the centrifugation process, causing damage to cell components, thereby affecting the stability of certain biomarkers.

[0004] In recent years, with the development of biomedical technology, gravity sedimentation has gradually attracted attention. Gravity sedimentation is a separation method based on the differences in the sedimentation rates of different substances in a gravitational field. It has the advantages of simplicity, low cost, and minimal damage to samples. However, the traditional gravity sedimentation process is generally slow and difficult to achieve simultaneous processing and precise control of multiple samples. This has, to a certain extent, limited its application in high-throughput detection fields such as folate metabolism.

[0005] To overcome the shortcomings of existing technologies and improve the efficiency and accuracy of folate metabolism testing, a device is needed that combines the advantages of gravity sedimentation and centrifugal stratification, while enabling simultaneous processing of multiple samples and precise control. Such a device should be able to stratify blood samples in a short period of time while avoiding unnecessary damage to cellular components. It should also be adaptable to different testing requirements, such as adjusting the stratification speed and controlling the degree of stratification.

[0006] Therefore, a gravity sedimentation separation tower and method for folic acid metabolism detection are needed to improve the above problems. Summary of the Invention

[0007] The object of the present invention is to provide a gravity sedimentation separation tower and method for folic acid metabolism detection, so as to solve the problems raised in the above background technology.

[0008] To achieve the above-mentioned purpose, the present invention provides the following technical solution: a gravity sedimentation sorting tower for folic acid metabolism detection, comprising a tower body, a lifting mechanism is provided on both sides of the tower body, a second motor is fixedly provided at the center bottom of the tower body, a support mechanism is provided for the transmission at the output end of the second motor, a conductive mechanism is installed at the upper end of the support mechanism, a plurality of gravity sedimentation trays are slidingly provided on the surface of the support mechanism, and a plurality of gravity sedimentation troughs are provided on the surface of the gravity sedimentation trays.

[0009] As an example of the present invention, the support mechanism includes a hollow column, a plurality of electric screws are fixedly provided inside the hollow column, and a lower hinged plate is provided at the output end of the electric screw.

[0010] As an example of the present invention, an upper hinge plate is fixedly provided inside the hollow column corresponding to the upper end of the lower hinge plate, and a plurality of hinge support plates are hingedly provided on the surface of the upper hinge plate. A hinge rod is hingedly provided at the other end of the hinge support plate, and the other end of the hinge rod is hingedly provided to the lower hinge plate.

[0011] As an example of the present invention, a plurality of through grooves are provided on the surface of the hollow column corresponding to the hinged rods, and a plurality of limiting ridges are fixedly provided on the surface of the hollow column.

[0012] As an example of the present invention, the conductive mechanism includes an insulating cylinder, inside which a positive electrode ring and a negative electrode ring are fixedly provided, and on the surfaces of the positive electrode ring and the negative electrode ring, a positive electrode conductive slider and a negative electrode conductive slider are respectively slidably provided.

[0013] As an example of the present invention, the conductive mechanism also includes an insulating mounting disk, which is fixedly arranged at the center of the upper end of the hollow column. A positive conductive column and a negative conductive column are fixedly arranged on both sides of the upper end of the insulating mounting disk at equal distances from the center, and the positive conductive column and the negative conductive column are fixedly connected to the positive conductive slider and the negative conductive slider respectively, and the positive conductive slider and the negative conductive slider are electrically connected to the electric screw.

[0014] As an example of the present invention, the lifting mechanism includes a sliding groove, a sliding rail is fixed on the inside of the sliding groove, an internal threaded slider is slidably provided on the surface of the sliding rail, a cylinder is fixed on both sides of the internal threaded slider, and a lifting support plate is driven at one end of the cylinder, and the lifting support plate is arranged in an L shape.

[0015] As an example of the present invention, the lifting mechanism further includes a motor 1, an output end of the motor 1 is provided with a screw rod, and the screw rod is threadedly connected to the internal thread slider.

[0016] A method for using a gravity sedimentation separation tower for folic acid metabolism detection comprises the following steps:

[0017] Step one: equipment inspection and preparation; before use, check whether the tower body, lifting mechanism, supporting mechanism, motor one, motor two, and conductive mechanism are normal, ensure that there is no damage or failure, thoroughly clean the inside of the tower, gravity sedimentation tray, gravity sedimentation tank, and conductive mechanism, ensure that there is no residue, avoid interference with the test results, adjust the temperature and humidity in the tower according to the requirements of folic acid metabolism detection, so that it meets the conditions suitable for gravity sedimentation, and ensure that the tower environment is stable;

[0018] Step two: placing test tubes; prepare the test tubes containing blood collected, ensure that the test tubes are sealed well and there is no leakage, open the tower body, and place the test tubes containing blood in the gravity sedimentation tank inside the gravity sedimentation tray, the gravity sedimentation tank is inclined outward, which is convenient for natural sedimentation and stratification of blood, arrange the test tubes on the gravity sedimentation tray according to the detection requirements, ensure that the distance between the test tubes is appropriate, and avoid mutual interference;

[0019] Step three: adjusting the position of the gravity sedimentation tray; start motor one, the output end of motor one drives the screw rod to rotate, the screw rod is connected with the internal thread slide block through screw thread, the internal thread slide block slides on the slide rail, thereby driving the lifting support plate to move up and down, the lifting support plate is L-shaped, which can stably support the gravity sedimentation tray and realize its up and down sliding on the surface of the supporting mechanism, adjust the gravity sedimentation tray to the appropriate position according to the detection requirements, stop motor one when the gravity sedimentation tray reaches the target position, and start the air cylinder to drive the lifting support plate to contract, so as to avoid the contact between the lifting support plate and the gravity sedimentation tray to be lifted in the subsequent operation;

[0020] Step four: supporting mechanism expansion; control the electric screw rod to drive the lower hinged plate to move through the transmission of the output end, the movement of the lower hinged plate will drive the hinged rod and the hinged support plate to expand, the hinged support plate extends through the through slot on the surface of the hollow column, thereby supporting the gravity sedimentation tray to be stably placed on the surface of the supporting mechanism, according to the requirements, multiple gravity sedimentation trays can be arranged on the surface of the supporting mechanism, under normal circumstances, the hinged support plate is retracted in the hollow column, and is expanded only when it needs to be supported;

[0021] Step five: use of the conductive mechanism; ensure that the surface of the positive ring and the negative ring inside the insulating cylinder of the conductive mechanism is free of dirt or damage, check whether the positive conductive slider and the negative conductive slider can slide smoothly, and ensure that they are in good contact with the positive ring and the negative ring, connect the external power supply to the positive ring and the negative ring of the conductive mechanism through the wire to electrify the electric screw rod, ensure that the power voltage and current meet the requirements of the equipment, and avoid overload or short circuit;

[0022] Step 6: Start gravity sedimentation separation. Since the gravity sedimentation tank is tilted outward, the blood will naturally settle and stratify. Under the action of gravity, the different components in the blood will gradually separate according to the density difference. For example, red blood cells, white blood cells, plasma, etc. will gradually separate. If you need to speed up the stratification speed or improve the stratification effect, you can start the second motor at the bottom through the conductive mechanism. The second motor drives the support mechanism to rotate, thereby driving the gravity sedimentation disk to rotate, using centrifugal force to accelerate the blood stratification.

[0023] Step 7: Monitoring and sampling; During the gravity sedimentation process, the sedimentation situation is monitored in real time through the observation window or sensor on the tower body and the stratification time, stratification effect and other data are recorded. When the sedimentation process is completed, according to the detection requirements, the test tube is removed from the gravity sedimentation tank for subsequent folic acid metabolism detection and analysis. After use, the tower body, gravity sedimentation plate, gravity sedimentation tank and conductive mechanism are cleaned to remove residual blood and other impurities.

[0024] Compared with the prior art, the present invention has the following beneficial effects:

[0025] 1. The present invention can use gravity to achieve preliminary stratification of blood through the natural tilt design of the gravity sedimentation tank. At the same time, combined with the centrifugal stratification function driven by motor 2, it can significantly accelerate the stratification speed and improve the stratification efficiency. It is particularly suitable for detection scenarios that require rapid processing of a large number of samples. The support mechanism can carry multiple gravity sedimentation trays at the same time, and each sedimentation tray can perform stratification operations independently. This multi-tray design greatly improves the processing capacity of the equipment, and can complete the stratification processing of multiple samples at the same time, significantly improving the detection efficiency and meeting the needs of high-throughput detection.

[0026] 2. The present invention drives the screw rod and the internal threaded slider through a motor, and the lifting support plate can accurately control the position of the gravity sedimentation tray on the support mechanism. This precise lifting and adjustment function allows the user to flexibly set the height of the sedimentation tray according to different detection requirements, thereby optimizing the stratification effect. The use of the electric screw rod realizes the precise control of the support mechanism, and can expand or contract the hinged support plate as needed to stably support the gravity sedimentation tray. This design not only improves the degree of automation of the equipment, but also ensures the stability of the sedimentation tray during the stratification process, avoiding incomplete stratification or sample damage due to shaking or instability.

[0027] 3. The conductive mechanism of the present invention realizes stable power supply to the electric screw and motor 2 through the design of the positive ring, negative ring and conductive slider. At the same time, it can flexibly switch the power supply according to needs to ensure the normal operation of the equipment in different operating modes. This intelligent conductive connection method further improves the flexibility and reliability of the equipment.

[0028] 4. The gravity sedimentation and centrifugal stratification methods adopted by the gravity sedimentation sorting tower of the present invention are relatively gentle, avoiding the damage to blood cell components caused by the severe mechanical stress that may occur in traditional centrifugal operations, thereby better protecting the bioactive substances in the sample and ensuring the accuracy and reliability of the test results. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 Schematic diagram of the overall internal structure of the present invention;

[0030] Figure 2 It is a schematic diagram of the overall internal three-dimensional structure of the present invention;

[0031] Figure 3 It is a schematic structural diagram of the support mechanism of the present invention;

[0032] Figure 4 Schematic diagram of the cross-sectional structure of the support mechanism of the present invention;

[0033] Figure 5 It is a schematic structural diagram of the lifting mechanism of the present invention;

[0034] Figure 6 This is a schematic diagram of the inner structure of the lifting mechanism of the present invention;

[0035] Figure 7 It is a partial enlarged structural diagram of the lifting mechanism of the present invention;

[0036] Figure 8 It is a partially enlarged structural schematic diagram of the support mechanism of the present invention;

[0037] Figure 9 It is a schematic structural diagram of the conductive mechanism of the present invention;

[0038] Figure 10 This is a schematic diagram of the structure of the gravity sedimentation tray of the present invention from a top view;

[0039] Figure 11 This is a schematic diagram of the lifting mechanism of the present invention from a top view;

[0040] Figure 12 It is a partially enlarged structural schematic diagram of the support mechanism of the present invention.

[0041] In the figure: 1. tower body; 2. gravity sedimentation plate; 3. supporting mechanism; 4. lifting mechanism; 5. conductive mechanism; 6. insulating cylinder; 7. positive ring; 8. positive conductive slider; 9. positive conductive column; 10. insulating mounting plate; 11. negative conductive slider; 12. negative conductive column; 13. negative ring; 14. electric screw; 15. lower hinge plate; 16. hinge rod; 17. upper hinge plate; 18. hinge support plate; 19. through groove; 20. hollow column; 21. limiting ridge; 22. motor 1; 23. screw; 24. internal thread slider; 25. cylinder; 26. lifting support plate; 27. sliding groove; 28. slide rail; 29. ​​motor 2; 30. gravity sedimentation tank. DETAILED DESCRIPTION

[0042] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0043] To facilitate understanding of the present invention, the present invention will be described more fully below with reference to related embodiments. Several embodiments of the present invention are provided. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a more thorough and comprehensive understanding of the present invention.

[0044] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be an intermediate element. When an element is referred to as being "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. The terms "vertical," "horizontal," "left," "right," and similar expressions used herein are for illustrative purposes only.

[0045] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this invention pertains. The terms used in this specification of the present invention are for the purpose of describing specific embodiments only and are not intended to limit the present invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0046] See also Figure 1-12The present invention provides a technical solution: a gravity sedimentation sorting tower for folic acid metabolism detection, comprising a tower body 1, with lifting mechanisms 4 on both sides of the tower body 1, a second motor 29 fixedly provided at the center bottom of the tower body 1, a support mechanism 3 provided for transmission at the output end of the second motor 29, a conductive mechanism 5 installed at the upper end of the support mechanism 3, a plurality of gravity sedimentation trays 2 slidingly provided on the surface of the support mechanism 3, and a plurality of gravity sedimentation troughs 30 provided on the surface of the gravity sedimentation tray 2; the position of the gravity sedimentation tray 2 is adjusted by the lifting mechanism 4, the second motor 29 drives the support mechanism 3 to rotate, and uses centrifugal force to accelerate blood stratification, and the conductive mechanism 5 provides power to the electric screw 14 to ensure stable operation of the equipment.

[0047] As an example of the present invention, the support mechanism 3 includes a hollow column 20, and a plurality of electric screw rods 14 are fixed inside the hollow column 20. The output end of the electric screw rod 14 is transmitted with a lower hinge plate 15; the electric screw rod 14 realizes the support and position adjustment of the gravity sedimentation plate 2 through the movement of the lower hinge plate 15.

[0048] As an example of the present invention, an upper hinged plate 17 is fixedly provided inside the hollow column 20 corresponding to the upper end of the lower hinged plate 15, and a plurality of hinged support plates 18 are hingedly provided on the surface of the upper hinged plate 17. The other end of the hinged support plate 18 is hingedly provided with a hinged rod 16, and the other end of the hinged rod 16 is hinged to the lower hinged plate 15; the design of the hinged support plate 18 and the hinged rod 16 enables the support mechanism 3 to be flexibly expanded and contracted, ensuring stable support of the gravity sedimentation tray 2.

[0049] As an example of the present invention, a plurality of through grooves 19 are provided on the surface of the hollow column 20 corresponding to the hinged rod 16, and a plurality of limiting ridges 21 are fixedly provided on the surface of the hollow column 20; the design of the through grooves 19 and the limiting ridges 21 ensures the stable movement of the hinged rod 16 and the hinged support plate 18, preventing them from shifting during the expansion and contraction process.

[0050] As an example of the present invention, the conductive mechanism 5 includes an insulating cylinder 6, on the inside of which a positive electrode ring 7 and a negative electrode ring 13 are fixedly provided, and on the surfaces of the positive electrode ring 7 and the negative electrode ring 13, a positive electrode conductive slider 8 and a negative electrode conductive slider 11 are respectively slidably provided; the design of the positive electrode conductive slider 8 and the negative electrode conductive slider 11 ensures a stable electrical connection between the conductive mechanism 5 and the electric screw 14, thereby improving the operating efficiency of the equipment.

[0051] As an example of the application, the conductive mechanism 5 further comprises an insulating mounting disc 10 fixedly arranged at the center of the upper end of the hollow column 20, positive and negative conductive columns 9 and 12 fixedly arranged at the two sides of the upper end of the insulating mounting disc 10 at equal distances from the center, and the positive and negative conductive columns 9 and 12 are fixedly connected with positive and negative conductive sliding blocks 8 and 11 respectively, and the positive and negative conductive sliding blocks 8 and 11 are electrically connected with the motorized lead screw 14; the design of the insulating mounting disc 10 and the conductive columns ensures the stable installation and electrical connection of the conductive mechanism 5, and improves the reliability and safety of the equipment.

[0052] As an example of the application, the lifting mechanism 4 comprises a sliding groove 27, a sliding rail 28 fixedly arranged inside the sliding groove 27, an internally threaded sliding block 24 slidingly arranged on the surface of the sliding rail 28, and a gas cylinder 25 fixedly arranged at the two sides of the internally threaded sliding block 24; one end of the gas cylinder 25 is drivingly provided with a lifting support plate 26 arranged in an L shape; the design of the sliding rail 28 and the internally threaded sliding block 24 ensures the stable movement of the lifting support plate 26, and the gas cylinder 25 provides the extension and retraction power of the lifting support plate 26.

[0053] As an example of the application, the lifting mechanism 4 further comprises a motor one 22, the output end of the motor one 22 is drivingly provided with a lead screw 23 in threaded connection with the internally threaded sliding block 24; the motor one 22 realizes the precise control of the lifting support plate 26 through the cooperation of the lead screw 23 and the internally threaded sliding block 24, and improves the automation degree of the equipment.

[0054] A method for using a gravity sedimentation sorting tower for folate metabolism detection, comprising the following steps:

[0055] Step one: equipment inspection and preparation; before use, check whether the tower body 1, lifting mechanism 4, support mechanism 3, motor one 22, motor two 29, conductive mechanism 5 and other components are normally operating, ensure that there is no damage or failure, thoroughly clean the tower body, gravity sedimentation disc 2, gravity sedimentation groove 30 and conductive mechanism 5 and other components to ensure that there is no residual material to avoid interference with the test results, adjust the temperature and humidity in the tower according to the requirements of folate metabolism detection to make it suitable for gravity sedimentation and ensure the stability of the tower environment;

[0056] Step two: placing test tubes; prepare the collected test tubes containing blood to ensure that the test tubes are well sealed and have no leakage, open the tower body, and place the test tubes containing blood one by one into the gravity sedimentation groove 30 inside the gravity sedimentation disc 2, the gravity sedimentation groove 30 is inclined outward to facilitate natural sedimentation and stratification of the blood, and arrange the test tubes on the gravity sedimentation disc reasonably according to the detection requirements to ensure appropriate spacing between the test tubes and avoid mutual interference;

[0057] Step 3: Adjust the position of the gravity sedimentation tray; start the motor 1 22, the output end of the motor 1 22 drives the screw rod 23 to rotate, the screw rod 23 is threadedly connected to the internal thread slider 24, and the internal thread slider 24 slides on the slide rail 28, thereby driving the lifting support plate 26 to move up and down. The lifting support plate 26 is set in an L shape, which can stably support the gravity sedimentation tray 2 and realize its up and down sliding on the surface of the support mechanism 3. According to the detection requirements, the gravity sedimentation tray 2 is adjusted to a suitable position. When the gravity sedimentation tray 2 reaches the target position, stop the motor 1 22 and start the cylinder 25. The cylinder 25 drives the lifting support plate 26 to retract to prevent the lifting support plate from contacting the gravity sedimentation tray 2 to be raised at the bottom during subsequent operations;

[0058] Step 4: Expand the support mechanism; by controlling the electric screw 14, the output end of the electric screw drives the lower hinge plate 15 to move. The movement of the lower hinge plate 15 drives the hinge rod 16 and the hinge support plate 18 to expand. The hinge support plate 18 extends through the through slot 19 on the surface of the hollow column 20, thereby supporting the gravity sedimentation tray 2 and placing it stably on the surface of the support mechanism 3. If needed, multiple gravity sedimentation trays 2 can be set on the surface of the support mechanism 3. Under normal circumstances, the hinge support plate 18 is retracted inside the hollow column 20 and is only expanded when support is needed.

[0059] Step 5: Use the conductive mechanism; ensure that the surfaces of the positive electrode ring 7 and the negative electrode ring 13 inside the insulating cylinder 6 of the conductive mechanism 5 are free of dirt or damage, check whether the positive conductive slider 8 and the negative conductive slider 11 can slide smoothly, and ensure that they are in good contact with the positive electrode ring 7 and the negative electrode ring 13. Connect the external power supply to the positive electrode ring 7 and the negative electrode ring 13 of the conductive mechanism 5 through a wire to energize the electric screw 14, and ensure that the power supply voltage and current meet the equipment requirements to avoid overload or short circuit;

[0060] Step 6: Start gravity sedimentation separation; Since the gravity sedimentation tank 30 is tilted outward, the blood will naturally settle and stratify. Under the action of gravity, different components in the blood will gradually separate according to density differences. For example, red blood cells, white blood cells, plasma, etc. will gradually separate. If it is necessary to speed up the stratification speed or improve the stratification effect, the second motor 29 at the bottom can be started by the conductive mechanism 5. The second motor 29 drives the support mechanism 3 to rotate, thereby driving the gravity sedimentation plate 2 to rotate, using centrifugal force to accelerate the blood stratification;

[0061] Step 7: Monitoring and sampling; During the gravity sedimentation process, the sedimentation situation is monitored in real time through the observation window or sensor on the tower body and other equipment, and the stratification time, stratification effect and other data are recorded. When the sedimentation process is completed, according to the detection requirements, the test tube is removed from the gravity sedimentation tank 30 for subsequent folic acid metabolism detection and analysis. After use, the tower body, gravity sedimentation plate 2, gravity sedimentation tank 30 and conductive mechanism 5 and other components are cleaned to remove residual blood and other impurities.

[0062] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A gravity sedimentation separation tower for folic acid metabolism detection, comprising a tower body (1), characterized in that: Lifting mechanisms (4) are provided on both sides of the tower body (1); a second motor (29) is fixedly provided at the center bottom of the tower body (1); a support mechanism (3) is provided at the output end of the second motor (29); a conductive mechanism (5) is installed at the upper end of the support mechanism (3); a plurality of gravity sedimentation plates (2) are slidably provided on the surface of the support mechanism (3); and a plurality of gravity sedimentation troughs (30) are provided on the surface of the gravity sedimentation plates (2).

2. The gravity sedimentation separation tower for folic acid metabolism detection according to claim 1, characterized in that: The support mechanism (3) comprises a hollow column (20), wherein a plurality of electric screw rods (14) are fixedly provided inside the hollow column (20), and a lower hinge plate (15) is provided at the output end of the electric screw rod (14).

3. A gravity sedimentation separation tower for folic acid metabolism detection according to claim 2, characterized in that: An upper hinge plate (17) is fixedly provided inside the hollow column (20) corresponding to the upper end of the lower hinge plate (15); a plurality of hinge support plates (18) are hingedly provided on the surface of the upper hinge plate (17); a hinge rod (16) is hingedly provided at the other end of the hinge support plate (18); and the other end of the hinge rod (16) is hingedly provided with the lower hinge plate (15).

4. The gravity sedimentation separation tower for folic acid metabolism detection according to claim 3, characterized in that: The surface of the hollow column (20) is provided with a plurality of through grooves (19) corresponding to the hinge rod (16), and the surface of the hollow column (20) is fixedly provided with a plurality of limiting ridges (21).

5. The gravity sedimentation separation tower for folic acid metabolism detection according to claim 4, characterized in that: The conductive mechanism (5) comprises an insulating cylinder (6), a positive electrode ring (7) and a negative electrode ring (13) are fixedly provided on the inner side of the insulating cylinder (6), and a positive electrode conductive slider (8) and a negative electrode conductive slider (11) are slidably provided on the surfaces of the positive electrode ring (7) and the negative electrode ring (13), respectively.

6. The gravity sedimentation separation tower for folic acid metabolism detection according to claim 5, characterized in that: The conductive mechanism (5) further comprises an insulating mounting plate (10), the insulating mounting plate (10) being fixedly arranged at the center of the upper end of the hollow column (20), and a positive conductive column (9) and a negative conductive column (12) being fixedly arranged on both sides of the upper end of the insulating mounting plate (10) at equal distances from the center, and the positive conductive column (9) and the negative conductive column (12) being fixedly connected to the positive conductive slider (8) and the negative conductive slider (11), respectively, and the positive conductive slider (8) and the negative conductive slider (11) being electrically connected to the electric screw (14).

7. The gravity sedimentation separation tower for folic acid metabolism detection according to claim 6, characterized in that: The lifting mechanism (4) comprises a sliding groove (27), a sliding rail (28) is fixedly provided inside the sliding groove (27), an internal thread slider (24) is slidingly provided on the surface of the sliding rail (28), a cylinder (25) is fixedly provided on both sides of the internal thread slider (24), and a lifting support plate (26) is provided at one end of the cylinder (25), and the lifting support plate (26) is arranged in an L shape.

8. The gravity sedimentation separation tower for folic acid metabolism detection according to claim 7, characterized in that: The lifting mechanism (4) further comprises a motor (22), the output end of the motor (22) is provided with a screw rod (23), and the screw rod (23) is threadedly connected to the internal thread slider (24).

9. The method for using the gravity sedimentation separation tower for folic acid metabolism detection according to any one of claims 1 to 8, characterized in that: The following steps are involved: Step 1: Equipment inspection and preparation; before use, check whether the tower body (1), lifting mechanism (4), supporting mechanism (3), motor 1 (22), motor 2 (29), and conductive mechanism (5) are operating normally to ensure that there is no damage or fault; thoroughly clean the interior of the tower body, gravity sedimentation plate (2), gravity sedimentation tank (30), and conductive mechanism (5) to ensure that there is no residue to avoid interference with the test results; according to the requirements of folic acid metabolism detection, adjust the temperature and humidity in the tower to achieve conditions suitable for gravity sedimentation and ensure that the environment in the tower is stable; Step 2: Place the test tube; Prepare the collected test tubes containing blood, ensure that the test tubes are well sealed and leak-free, open the tower body, and place the test tubes containing blood one by one into the gravity sedimentation tank (30) inside the gravity sedimentation tray (2). The gravity sedimentation tank (30) is tilted outward to facilitate the natural sedimentation and stratification of blood. According to the detection requirements, the distribution of the test tubes on the gravity sedimentation tray is reasonably arranged to ensure that the spacing between the test tubes is appropriate to avoid mutual interference; Step 3: Adjust the position of the gravity sedimentation tray; start the motor 1 (22), the output end of the motor 1 (22) drives the screw rod (23) to rotate, the screw rod (23) is threadedly connected to the internal thread slider (24), the internal thread slider (24) slides on the slide rail (28), thereby driving the lifting support plate (26) to move up and down, the lifting support plate (26) is set in an L shape, and can stably support the gravity sedimentation tray (2) to achieve its up and down sliding on the surface of the support mechanism (3), according to the detection requirements, the gravity sedimentation tray (2) is adjusted to a suitable position, when the gravity sedimentation tray (2) reaches the target position, stop the motor 1 (22), start the cylinder (25), and the cylinder (25) drives the lifting support plate (26) to retract, so as to prevent the lifting support plate from contacting the gravity sedimentation tray (2) to be raised at the bottom during subsequent operations; Step 4: Expand the support mechanism; by controlling the electric screw (14), the output end of the electric screw (14) is driven to drive the lower hinge plate (15) to move. The movement of the lower hinge plate (15) drives the hinge rod (16) and the hinge support plate (18) to expand. The hinge support plate (18) extends through the through groove (19) on the surface of the hollow column (20), thereby supporting the gravity sedimentation plate (2) and placing it stably on the surface of the support mechanism (3). As needed, multiple gravity sedimentation plates (2) can be set on the surface of the support mechanism (3). Under normal circumstances, the hinge support plate (18) is retracted inside the hollow column (20) and is expanded only when support is required. Step 5: Use the conductive mechanism; ensure that the surfaces of the positive electrode ring (7) and the negative electrode ring (13) inside the insulating cylinder (6) of the conductive mechanism (5) are free of dirt or damage, check whether the positive electrode conductive slider (8) and the negative electrode conductive slider (11) can slide smoothly, and ensure that they are in good contact with the positive electrode ring (7) and the negative electrode ring (13), connect the external power supply to the positive electrode ring (7) and the negative electrode ring (13) of the conductive mechanism (5) through a wire to energize the electric screw (14), and ensure that the power supply voltage and current meet the equipment requirements to avoid overload or short circuit; Step 6: Start gravity sedimentation separation; since the gravity sedimentation tank (30) is tilted outward, the blood will naturally settle and separate. Under the action of gravity, different components in the blood will gradually separate according to density differences. For example, red blood cells, white blood cells, and plasma will gradually separate. If it is necessary to speed up the separation speed or improve the separation effect, the second motor (29) at the bottom can be started through the conductive mechanism (5). The second motor (29) drives the support mechanism (3) to rotate, thereby driving the gravity sedimentation plate (2) to rotate, and using centrifugal force to accelerate the blood separation. Step 7: Monitoring and sampling; During the gravity sedimentation process, the sedimentation situation is monitored in real time through the observation window or sensor equipment on the tower body, and the stratification time and stratification effect data are recorded. When the sedimentation process is completed, according to the detection requirements, the test tube is removed from the gravity sedimentation tank (30) and subsequent folic acid metabolism detection and analysis is carried out. After use, the tower body, gravity sedimentation plate (2), gravity sedimentation tank (30) and conductive mechanism (5) components are cleaned to remove residual blood and other impurities.

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