POCT blood cell analyzer

Abstract

The invention discloses a POCT hematology analyzer. The POCT hematology analyzer comprises a shell; the loading seat is used for receiving the loading of the kit; the blood cell counting mechanism is arranged in the shell and can move relative to the kit; the blood cell counting mechanism includes: a body; the liquid suction part is matched with the main body to form a liquid suction channel for conveying liquid; the liquid discharging part is matched with the main body to form a liquid discharging channel for discharging liquid of the main body; and when the liquid suction channel is blocked, the blood cell counting mechanism is arranged to impact the liquid suction channel through gas in the main body, or suck liquid through the liquid discharge piece and impact the liquid suction channel through the liquid. According to the mode, the liquid suction channel is impacted by gas or liquid, so that the accuracy of a detection result of the POCT blood cell analyzer is improved; the microporous sheet of the blood cell counting mechanism does not need to be frequently replaced, the use time of the microporous sheet is delayed, and the cost is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of blood cell counting, in particular to a POCT blood cell analyzer. BACKGROUND

[0002] The blood cell counting device is used for counting sample liquid to allow cell particles of the sample liquid to pass through a gem hole of the particle counting device, and counting is achieved by detecting the impedance of the cell particles passing through the gem hole.

[0003] The gem hole sheet of the prior art blood cell counting device is used for detecting a plurality of detection samples. When the detection quantity of the blood cell counting device reaches a preset quantity or the blood cell counting device abnormally alarms, the gem hole sheet may appear a hole blocking phenomenon. An operator needs to replace the gem hole sheet, which increases the cost. SUMMARY

[0004] In view of the above problems, the present application provides a POCT blood cell analyzer, which performs cleaning and maintenance on a blood cell counting mechanism in a maintenance mode, reduces the frequency of replacing a micropore sheet of the blood cell counting mechanism, and reduces the cost.

[0005] In a first aspect, the present application provides a POCT blood cell analyzer, comprising:

[0006] a housing;

[0007] a loading seat for receiving a kit;

[0008] a blood cell counting mechanism arranged in the housing, the blood cell counting mechanism being movable relative to the kit;

[0009] The blood cell counting mechanism comprises:

[0010] a main body;

[0011] a liquid suction member cooperating with the main body to form a liquid suction channel for conveying liquid, the liquid suction channel being provided with a micropore sheet;

[0012] a liquid discharge member cooperating with the main body to form a liquid discharge channel for discharging liquid from the main body;

[0013] When the liquid suction channel is blocked, the blood cell counting mechanism is arranged to impact the liquid suction channel by gas in the main body, or to suck liquid by the liquid discharge member and impact the liquid suction channel by the liquid.

[0014] In some embodiments, after the liquid suction passage is impacted by the gas, and when the liquid suction passage is blocked, the blood cell counting mechanism is configured to suck liquid from the liquid discharge member and impact the liquid suction passage by the liquid.

[0015] In some embodiments, the loading seat is further configured to receive a maintenance kit, and the blood cell counting mechanism is movable relative to the maintenance kit.

[0016] The blood cell counting mechanism is configured to suck liquid from the maintenance kit by the liquid discharge member and impact the liquid suction passage by the liquid.

[0017] In some embodiments, the maintenance kit comprises a backflushing liquid pool configured to store liquid, and the blood cell counting mechanism is configured to suck liquid from the backflushing liquid pool by the liquid discharge member and impact the liquid suction passage by the liquid.

[0018] In some embodiments, the maintenance kit comprises a plurality of cleaning liquid pools configured to store cleaning liquid with different cleaning intensities, and at least one of the plurality of cleaning liquid pools is used as the backflushing liquid pool, and when the liquid suction passage is blocked, the blood cell counting mechanism is configured to suck the cleaning liquid from at least one of the plurality of cleaning liquid pools by the liquid discharge member and impact the liquid suction passage by the cleaning liquid.

[0019] In some embodiments, the maintenance kit further comprises a second waste liquid pool disposed adjacent to the backflushing liquid pool, and when the liquid suction passage is blocked, the blood cell counting mechanism is configured to suck liquid from the backflushing liquid pool by the liquid discharge member and impact the liquid suction passage by the liquid, and the second waste liquid pool is configured to accommodate the liquid discharge member and accommodate liquid discharged by the impact.

[0020] In some embodiments, when the impacted liquid suction passage is not blocked, the blood cell counting mechanism is configured to suck the cleaning liquid from different cleaning liquid pools by the liquid discharge member in descending order of cleaning intensity, and discharge the cleaning liquid in the main body to the maintenance kit by the liquid discharge member.

[0021] In some embodiments, the maintenance kit further comprises a first waste liquid pool adjacent to the cleaning liquid pool with the highest cleaning intensity, and the blood cell counting mechanism is configured to insert the liquid discharge member into the cleaning liquid pool with the highest cleaning intensity while inserting the liquid discharge member into the first waste liquid pool.

[0022] In some embodiments, the blood cell counting mechanism further comprises a switch valve, the main body is provided with a liquid discharge hole, the liquid discharge member is in communication with the liquid discharge hole through the switch valve to form the liquid discharge channel; when the liquid discharge member sucks liquid, the switch valve is controlled to be turned on; when the gas or the liquid impacts the liquid suction channel, the switch valve is controlled to be turned off.

[0023] In some embodiments, the blood cell counting mechanism is provided with a detection mode, the loading seat is further used for receiving a detection reagent kit, and the blood cell counting mechanism is movable relative to the detection reagent kit.

[0024] In the detection mode, the blood cell counting mechanism sucks detection liquid from the detection reagent kit through the liquid suction member and discharges the detection liquid in the main body to the detection reagent kit through the liquid discharge member.

[0025] Compared with the prior art, the blood cell counting mechanism comprises a main body, a liquid suction member, a liquid discharge member, and the like. When the liquid suction channel is blocked, the blood cell counting mechanism is provided with a gas in the main body to impact the liquid suction channel or a liquid sucked from a reagent kit to impact the liquid suction channel. When the liquid suction channel is blocked, the liquid suction channel is impacted by the gas or the liquid to make the POCT blood cell analyzer have the ability to process the blockage of the liquid suction channel, can probably solve the blockage of the liquid suction channel, improve the detection result accuracy of the POCT blood cell analyzer, and delay the service life of the microporous sheet of the blood cell counting mechanism, thereby reducing the cost. BRIEF DESCRIPTION OF DRAWINGS

[0026] Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The accompanying drawings are included to provide a better understanding of the preferred embodiments, and are not to be considered as limiting of the present application. Moreover, in the drawings, like reference numerals refer to similar components throughout the several views. In the drawings:

[0027] Figure 1 is a structural schematic diagram of a first embodiment of the POCT blood cell analyzer of the present application;

[0028] Figure 2 is Figure 1 a structural schematic diagram of a first embodiment of the blood cell counting mechanism in the POCT blood cell analyzer

[0029] Figure 3 is Figure 1 a structural schematic diagram of a first embodiment of the maintenance reagent kit in the POCT blood cell analyzer

[0030] Figure 4 is Figure 1 is a structural schematic diagram of a second embodiment of the maintenance kit in the

[0031] Figure 5 is a structural schematic diagram of a second embodiment of the POCT blood cell analyzer of the present application;

[0032] Figure 6 is a flow schematic diagram of a first embodiment of the maintenance method of the POCT blood cell analyzer of the present application;

[0033] Figure 7 is Figure 1 is a structural schematic diagram of a third embodiment of the maintenance kit in the

[0034] Figure 8 is Figure 1 is a structural schematic diagram of a fourth embodiment of the maintenance kit in the

[0035] Figure 9 is Figure 2 is a structural schematic diagram of a local amplification of the region A in the

[0036] Figure 10 is a structural schematic diagram of a first embodiment of the pressure mechanism of the present application;

[0037] Figure 11 is a structural schematic diagram of a second embodiment of the pressure mechanism of the present application. DETAILED DESCRIPTION

[0038] The embodiments of the technical solutions of the present application will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solutions of the present application, and therefore only serve as examples, and cannot limit the protection scope of the present application.

[0039] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present application belongs; the terms used herein are only for the purpose of describing specific embodiments of the present application, and are not intended to limit the present application; the terms "include" and "have" and any variations thereof in the specification and claims of the present application and the above description of drawings are intended to cover non-exclusive inclusion.

[0040] In the description of the embodiments of the present application, the technical terms "first", "second", etc. are only used to distinguish different objects, and cannot be understood as indicating or implying relative importance or implicitly indicating the number, specific order or primary and secondary relationship of the indicated technical features. In the description of the embodiments of the present application, the meaning of "a plurality of" is two or more, unless otherwise explicitly specified.

[0041] Reference to“an embodiment” herein means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase“in an embodiment” in various places in the specification are not necessarily all referring to the same embodiment, nor are they necessarily mutually exclusive of one another. It is expressly understood that any of the embodiments described herein can be incorporated into any other embodiment.

[0042] In the description of the embodiments of the application, the term“and / or” only means an association relationship of the associated objects, which means that there can be three relationships, for example, A and / or B, which can mean that A exists alone, A and B exist together, and B exists alone. In addition, the character“ / ” herein generally means that the front and rear associated objects are in an“or” relationship.

[0043] In the description of the embodiments of the application, the term“a plurality of” means more than two (including two), and similarly, “a plurality of groups” means more than two groups (including two groups), and “a plurality of pieces” means more than two pieces (including two pieces).

[0044] In the description of the embodiments of the application, the technical terms“center”,“longitudinal”,“transverse”,“length”,“width”,“thickness”,“upper”,“lower”,“front”,“rear”,“left”,“right”,“vertical”,“horizontal”,“top”,“bottom”,“inner”,“outer”,“clockwise”,“counterclockwise”,“axial”,“radial”,“circumferential” and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the embodiments of the application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the embodiments of the application.

[0045] In the description of the embodiments of the application, unless otherwise explicitly specified and limited, the technical terms“mounting”,“connection”,“connection”,“fixing” and the like should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the internal communication of two elements or the interaction relationship of two elements. For those skilled in the art, the specific meaning of the above terms in the embodiments of the application can be understood according to the specific circumstances.

[0046] Please refer to Figure 1 and Figure 2 As shown in Figure 1 is a structural schematic diagram of a first embodiment of a POCT blood cell analyzer of the application; Figure 2 is Figure 1 a structural schematic diagram of a first embodiment of a blood cell counting mechanism.

[0047] The POCT blood cell analyzer 1 of the embodiment comprises a shell (not shown in the figure), a loading seat (not shown in the figure) and a blood cell counting mechanism 10. The blood cell counting mechanism 10 can also be referred to as a blood cell counting component or a blood cell counting pool.

[0048] The blood cell counting mechanism 10 is arranged in the shell, and the loading seat is used to receive the maintenance kit 20. For example, the loading seat is arranged in the shell. When the loading seat receives the maintenance kit 20, the loading seat moves out of the shell, so that the maintenance kit 20 is placed on the loading seat and the maintenance kit 20 is moved into the shell, thereby realizing that the loading seat receives the maintenance kit 20.

[0049] The blood cell counting mechanism 10 can move relative to the maintenance kit 20. Specifically, the blood cell counting mechanism 10 moves, and the maintenance kit 20 does not move; or the blood cell counting mechanism 10 moves, and the maintenance kit 20 moves; or the blood cell counting mechanism 10 does not move, and the maintenance kit 20 moves.

[0050] The maintenance kit 20 comprises a plurality of cleaning liquid pools 21 for storing cleaning liquids with different cleaning intensities. For example, the plurality of cleaning liquid pools 21 are arranged adjacent to each other in order of cleaning intensity from high to low, or the plurality of cleaning liquid pools 21 are arranged randomly.

[0051] The blood cell counting mechanism 10 of the embodiment comprises a main body 11, a liquid suction member 12 and a liquid discharge member 13. The liquid suction member 12 cooperates with the main body 11 to form a liquid suction channel for conveying liquid, and the liquid discharge member 13 cooperates with the main body 11 to form a liquid discharge channel for discharging liquid from the main body.

[0052] Optionally, the main body 11 is provided with an inner cavity 111, which is in communication with the liquid discharge channel and the liquid suction channel respectively. The inner cavity 111 can also be referred to as a rear cavity or a rear pool.

[0053] The blood cell counting mechanism 10 is provided with a maintenance mode in advance. Specifically, when the number of detections of the blood cell counting mechanism 10 reaches a preset number, or the POCT blood cell analyzer 1 appears abnormal, or before the POCT blood cell analyzer 1 is started or turned off, or the POCT blood cell analyzer 1 prompts that maintenance is needed, the blood cell counting mechanism 10 enters the maintenance mode. The number of detections of the blood cell counting mechanism 10 refers to the number of times of counting detection of liquid completed by the blood cell counting mechanism 10. The abnormality of the POCT blood cell analyzer 1 includes but is not limited to the blockage of the microwell sheet 17 of the blood cell counting mechanism 10 or the blockage of the liquid suction channel.

[0054] Among them, the blood cell counting mechanism 10 is pre-set with a maintenance mode, but it is not necessary to have a maintenance mode; when the blood cell counting mechanism 10 meets the maintenance conditions, the blood cell counting mechanism 10 performs automatic maintenance, which also belongs to the maintenance mode of this application.

[0055] In the maintenance mode, the blood cell counting mechanism 10 is configured to absorb cleaning fluid from different cleaning fluid pools 21 through the liquid aspirator 12 according to the cleaning intensity from high to low, and discharge the cleaning fluid in the main body 11 into the maintenance reagent kit 20 through the liquid discharger 13 .

[0056] For example, when the blood cell counting mechanism 10 enters the maintenance mode, the blood cell counting mechanism 10 draws cleaning fluid from the cleaning fluid reservoir 21 with the highest cleaning intensity through the liquid aspirator 12, and discharges the cleaning fluid in the main body 11 into the maintenance reagent kit 20 through the liquid discharger 13. The blood cell counting mechanism 10 draws cleaning fluid from the cleaning fluid reservoir 21 with the higher cleaning intensity through the liquid aspirator 12, and discharges the cleaning fluid in the main body 11 into the maintenance reagent kit 20 through the liquid discharger 13. The blood cell counting mechanism 10 draws cleaning fluid from the cleaning fluid reservoir 21 with the weakest cleaning intensity through the liquid aspirator 12, and discharges the cleaning fluid in the main body 11 into the maintenance reagent kit 20 through the liquid discharger 13.

[0057] In the maintenance mode of this embodiment, the blood cell counting mechanism 10 is configured to draw cleaning fluid from different cleaning fluid pools 21 via the liquid aspirator 12 according to the cleaning intensity from high to low, and to discharge the cleaning fluid in the main body 11 into the maintenance reagent kit 20 via the liquid discharger 13. By performing multiple cleanings on the blood cell counting mechanism 10 according to the cleaning intensity from high to low in the maintenance mode, the blood cell counting mechanism 10 is cleaned and maintained, and waste liquid residue in the inner cavity 111, the liquid aspirator channel, and the liquid discharge channel of the main body 11 is reduced, thereby improving the accuracy of the test results of the POCT blood cell analyzer 1. In addition, by performing multiple cleanings on the microporous sheet 17 of the blood cell counting mechanism 10 according to the cleaning intensity from high to low, the probability of clogging of the microporous sheet 17 is reduced, the frequency of replacing the microporous sheet 17 is reduced, and the cost is reduced. In addition, by performing multiple cleanings on the blood cell counting mechanism 10 according to the cleaning intensity from high to low in the maintenance mode, the cleaning effect of the blood cell counting mechanism 10 can be improved, thereby improving the accuracy of the test results of the POCT blood cell analyzer 1.

[0058] According to some embodiments of this application, see Figures 1-3 As shown, Figure 3 yes Figure 1 Schematic diagram of the structure of the first embodiment of the maintenance kit. The multiple cleaning liquid pools 21 of this embodiment include a first cleaning liquid pool 211, a second cleaning liquid pool 212, and a third cleaning liquid pool 213. The first cleaning liquid pool 211, the second cleaning liquid pool 212, and the third cleaning liquid pool 213 are arranged in sequence along the extension direction of the maintenance kit 20.

[0059] The cleaning strength of the cleaning liquid in the first cleaning liquid pool 211 is greater than the cleaning strength of the cleaning liquid in the second cleaning liquid pool 212, and the cleaning strength of the cleaning liquid in the second cleaning liquid pool 212 is greater than or equal to the cleaning strength of the cleaning liquid in the third cleaning liquid pool 213.

[0060] For example, the cleaning liquid in the first cleaning liquid pool 211 is a strong alkaline cleaning liquid, the cleaning liquid in the second cleaning liquid pool 212 is a weak acid cleaning liquid, and the cleaning liquid in the third cleaning liquid pool 213 is pure water; or the cleaning liquid in the first cleaning liquid pool 211 is a strong alkaline cleaning liquid, the cleaning liquid in the second cleaning liquid pool 212 is pure water, and the cleaning liquid in the third cleaning liquid pool 213 is pure water.

[0061] The blood cell counting mechanism 10 sequentially sucks the cleaning liquid from the first cleaning liquid pool 211, the second cleaning liquid pool 212, and the third cleaning liquid pool 213 through the liquid suction member 12.

[0062] Specifically, in the maintenance mode, the blood cell counting mechanism 10 sucks the cleaning liquid from the first cleaning liquid pool 211 through the liquid suction member 12 to soak the inner cavity 111 to remove foreign matter in the inner cavity 111, and discharges the cleaning liquid in the inner cavity 111 of the main body 11 to the maintenance reagent box 20 through the liquid discharge member 13. The blood cell counting mechanism 10 sucks the cleaning liquid from the second cleaning liquid pool 212 through the liquid suction member 12 to clean the inner cavity 111, and discharges the cleaning liquid in the inner cavity 111 of the main body 11 to the maintenance reagent box 20 through the liquid discharge member 13. The blood cell counting mechanism 10 sucks the cleaning liquid from the third cleaning liquid pool 213 through the liquid suction member 12 to clean the inner cavity 111, and discharges the cleaning liquid in the inner cavity 111 of the main body 11 to the maintenance reagent box 20 through the liquid discharge member 13.

[0063] The blood cell counting mechanism 10 of the embodiment sequentially sucks the cleaning liquid from the first cleaning liquid pool 211, the second cleaning liquid pool 212, and the third cleaning liquid pool 213 through the liquid suction member 12, wherein the cleaning strength of the cleaning liquid in the first cleaning liquid pool 211 is greater than the cleaning strength of the cleaning liquid in the second cleaning liquid pool 212, and the cleaning strength of the cleaning liquid in the second cleaning liquid pool 212 is greater than or equal to the cleaning strength of the cleaning liquid in the third cleaning liquid pool 213. The liquid suction channel, the inner cavity 111, and the liquid discharge channel can be cleaned from high to low according to the cleaning strength, the cleaning effect of the blood cell counting mechanism 10 is improved, the cleaning liquid residue is reduced, and the detection result accuracy of the POCT blood cell analyzer 1 is improved.

[0064] According to some embodiments of the present application, the blood cell counting mechanism 10 of the embodiment is configured to discharge the cleaning liquid in the main body 11 to the cleaning liquid pool 21 which has sucked the cleaning liquid through the liquid discharge member 13.

[0065] When the blood cell counting mechanism 10 finishes sucking the cleaning liquid from the cleaning liquid pool 21 by the liquid suction member 12, the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the cleaning liquid pool 21 by the liquid discharge member 13.

[0066] For example, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 is inserted into the first cleaning liquid pool 211 and the blood cell counting mechanism 10 sucks the cleaning liquid from the first cleaning liquid pool 211 by the liquid suction member 12. When the blood cell counting mechanism 10 finishes sucking the cleaning liquid from the first cleaning liquid pool 211 by the liquid suction member 12, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 is inserted into the second cleaning liquid pool 212, the liquid discharge member 13 is inserted into the first cleaning liquid pool 211, and the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the first cleaning liquid pool 211 by the liquid discharge member 13, thereby completing the first cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 sucks the cleaning liquid from the second cleaning liquid pool 212 by the liquid suction member 12. When the blood cell counting mechanism 10 finishes sucking the cleaning liquid from the second cleaning liquid pool 212 by the liquid suction member 12, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 is inserted into the third cleaning liquid pool 213, the liquid discharge member 13 is inserted into the second cleaning liquid pool 212, and the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the second cleaning liquid pool 212 by the liquid discharge member 13, thereby completing the second cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 sucks the cleaning liquid from the third cleaning liquid pool 213 by the liquid suction member 12 and discharges the cleaning liquid in the main body 11 to the second cleaning liquid pool 212 by the liquid discharge member 13, or the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid discharge member 13 is inserted into the third cleaning liquid pool 213 and discharges the cleaning liquid in the main body 11 to the third cleaning liquid pool 213 by the liquid discharge member 13, thereby completing the third cleaning of the blood cell counting mechanism 10.

[0067] Alternatively, when the liquid suction member 12 of the blood cell counting mechanism 10 is inserted into the first cleaning liquid pool 211, the liquid discharge member 13 of the blood cell counting mechanism 10 is located outside the first cleaning liquid pool 211, for example, the liquid discharge member 13 is located on the side of the first cleaning liquid pool 211 away from the second cleaning liquid pool 212.

[0068] Optionally, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 and the liquid discharge member 13 are inserted into the first cleaning liquid pool 211, cleaning liquid is sucked from the first cleaning liquid pool 211 by the liquid suction member 12, and cleaning liquid in the main body 11 is discharged to the first cleaning liquid pool 211 by the liquid discharge member 13, thereby completing the first cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 and the liquid discharge member 13 are inserted into the second cleaning liquid pool 212, cleaning liquid is sucked from the second cleaning liquid pool 212 by the liquid suction member 12, and cleaning liquid in the main body 11 is discharged to the second cleaning liquid pool 212 by the liquid discharge member 13, thereby completing the second cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 and the liquid discharge member 13 are inserted into the third cleaning liquid pool 213, cleaning liquid is sucked from the third cleaning liquid pool 213 by the liquid suction member 12, and cleaning liquid in the main body 11 is discharged to the third cleaning liquid pool 213 by the liquid discharge member 13, thereby completing the third cleaning of the blood cell counting mechanism 10.

[0069] The blood cell counting mechanism 10 of the embodiment is arranged to discharge cleaning liquid in the main body 11 to the cleaning liquid pool 21 from which the cleaning liquid has been sucked, without discharging the cleaning liquid in the main body 11 to the waste liquid pool, so that the operation is simple and the detection efficiency of the POCT blood cell analyzer 1 is improved. In addition, the maintenance kit 20 does not need to be additionally provided with a waste liquid pool, so that the volume of the maintenance kit 20 is reduced and the cost is reduced.

[0070] According to some embodiments of the application, the plurality of cleaning liquid pools 21 of the embodiment are arranged in order of decreasing cleaning strength, for example, the plurality of cleaning liquid pools 21 include the first cleaning liquid pool 211, the second cleaning liquid pool 212, and the third cleaning liquid pool 213, and the first cleaning liquid pool 211, the second cleaning liquid pool 212, and the third cleaning liquid pool 213 are arranged in order of decreasing cleaning strength.

[0071] The blood cell counting mechanism 10 is arranged to insert the liquid suction member 12 into the current cleaning liquid pool 21 from which cleaning liquid is currently sucked, and insert the liquid discharge member 13 into the previous cleaning liquid pool 21 from which cleaning liquid has been sucked, which is adjacent to the current cleaning liquid pool 21.

[0072] For example, the blood cell counting mechanism 10 inserts the liquid suction member 12 into the second cleaning liquid pool 212 while inserting the liquid discharge member 13 into the first cleaning liquid pool 211, where the second cleaning liquid pool 212 is the current cleaning liquid pool 21 currently sucking the cleaning liquid, and the first cleaning liquid pool 211 is the previous cleaning liquid pool 21 adjacent to the current cleaning liquid pool 21 and having sucked the cleaning liquid; or the blood cell counting mechanism 10 inserts the liquid suction member 12 into the third cleaning liquid pool 213 while inserting the liquid discharge member 13 into the second cleaning liquid pool 212, where the third cleaning liquid pool 213 is the current cleaning liquid pool 21 currently sucking the cleaning liquid, and the second cleaning liquid pool 212 is the previous cleaning liquid pool 21 adjacent to the current cleaning liquid pool 21 and having sucked the cleaning liquid.

[0073] The plurality of cleaning liquid pools 21 of the embodiment are arranged in order of decreasing cleaning strength, and the blood cell counting mechanism 10 is configured to insert the liquid suction member 12 into the current cleaning liquid pool 21 currently sucking the cleaning liquid while inserting the liquid discharge member 13 into the previous cleaning liquid pool 21 adjacent to the current cleaning liquid pool 21 and having sucked the cleaning liquid. This improves the detection efficiency of the POCT blood cell analyzer 1 and simplifies the operation. In addition, the maintenance reagent kit 20 does not need to be additionally provided with a waste liquid pool, thereby reducing the volume of the maintenance reagent kit 20 and lowering the cost.

[0074] According to some embodiments of the present application, please refer to Figure 1 、 Figure 2 and Figure 4 , Figure 4 is Figure 1 a structural schematic diagram of a second embodiment of the maintenance reagent kit in

[0075] Specifically, the plurality of cleaning liquid pools 21 include a first cleaning liquid pool 211, a second cleaning liquid pool 212, and a third cleaning liquid pool 213, which are arranged in order along the extension direction of the maintenance reagent kit 20. The cleaning strength of the cleaning liquid in the first cleaning liquid pool 211 is greater than that of the cleaning liquid in the second cleaning liquid pool 212, and the cleaning strength of the cleaning liquid in the second cleaning liquid pool 212 is greater than or equal to that of the cleaning liquid in the third cleaning liquid pool 213. The first waste liquid pool 22 is arranged on the side of the first cleaning liquid pool 211 away from the second cleaning liquid pool 212.

[0076] The blood cell counting mechanism 10 is configured to insert the liquid suction member 12 into the cleaning liquid pool 21 with the strongest cleaning strength while inserting the liquid discharge member 13 into the first waste liquid pool 22.

[0077] In the maintenance mode, the liquid aspirator 12 is inserted into the first cleaning liquid reservoir 211 while the liquid discharger 13 is inserted into the first waste liquid reservoir 22. The blood cell counting mechanism 10 absorbs the cleaning liquid from the first cleaning liquid reservoir 211 through the liquid aspirator 12 and discharges the cleaning liquid from the inner cavity 111 into the first waste liquid reservoir 22 through the liquid discharger 13, thereby completing the first cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 is movable relative to the maintenance reagent kit 20. The liquid aspirator 12 is inserted into the second cleaning liquid reservoir 212 while the liquid discharger 13 is inserted into the first cleaning liquid reservoir 211. The blood cell counting mechanism 10 absorbs the cleaning liquid from the second cleaning liquid reservoir 212 through the liquid aspirator 12 and discharges the cleaning liquid from the inner cavity 111 into the first cleaning liquid reservoir 211 through the liquid discharger 13, thereby completing the second cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 can be moved relative to the maintenance reagent kit 20. When the liquid aspirator 12 is inserted into the third cleaning liquid tank 213, the liquid discharger 13 is inserted into the second cleaning liquid tank 212. The blood cell counting mechanism 10 absorbs the cleaning liquid from the third cleaning liquid tank 213 through the liquid aspirator 12, and discharges the cleaning liquid from the inner cavity 111 into the second cleaning liquid tank 212 through the liquid discharger 13, thereby completing the third cleaning of the blood cell counting mechanism 10.

[0078] Optionally, the spacing distance between the liquid absorption component 12 and the liquid discharge component 13 is equal to the distance between the central axis of the first waste liquid pool 22 and the central axis of the first cleaning liquid pool 211, or the distance between the central axis of the first cleaning liquid pool 211 and the central axis of the second cleaning liquid pool 212, or the distance between the central axis of the second cleaning liquid pool 212 and the central axis of the third cleaning liquid pool 213.

[0079] The maintenance kit 20 of this embodiment also includes a first waste liquid tank 22 adjacent to the cleaning liquid tank 21 with the strongest cleaning intensity. The blood cell counting mechanism 10 is configured such that the liquid aspirator 12 is inserted into the cleaning liquid tank 21 with the strongest cleaning intensity while the liquid drainer 13 is inserted into the first waste liquid tank 22. The liquid drainer 13 can drain the cleaning liquid from the inner cavity 111 into the first waste liquid tank 22, simplifying operation and improving the detection efficiency of the POCT hematology analyzer 1. By providing the first waste liquid tank 22, when the first cleaning liquid tank 211 draws cleaning liquid for cleaning, the liquid can be drained without moving to the second cleaning liquid tank 212. When the second cleaning liquid tank 212 draws cleaning liquid for cleaning, the liquid can be drained without moving to the third cleaning liquid tank 213. When the third cleaning liquid tank 213 draws cleaning liquid for cleaning, the liquid can be drained directly. Taking into account that a small amount of cleaning liquid will also be discharged from the liquid suction channel during drainage, compared with the first embodiment, this embodiment basically does not discharge the cleaning liquid of the first cleaning liquid pool 211 to the second cleaning liquid pool 212 through the liquid suction component 12, nor does it discharge the cleaning liquid of the second cleaning liquid pool 212 to the third cleaning liquid pool 213 through the liquid suction component 12, thereby making cleaning more thorough.

[0080] According to some embodiments of the present application, the blood cell counting mechanism 10 is arranged to sequentially increase the liquid amount of the washing liquid sequentially drawn by the liquid suction member 12 from different washing liquid pools 21 according to the washing strength from high to low.

[0081] As shown in FIGS. 1, 2 and 3, the blood cell counting mechanism 10 draws the washing liquid of the first washing liquid pool 211 through the liquid suction member 12 with a first liquid amount, the blood cell counting mechanism 10 draws the washing liquid of the second washing liquid pool 212 through the liquid suction member 12 with a second liquid amount, the blood cell counting mechanism 10 draws the washing liquid of the third washing liquid pool 213 through the liquid suction member 12 with a third liquid amount, the second liquid amount is greater than the first liquid amount, and the third liquid amount is greater than the second liquid amount. Figure 1 Figure 4 As shown in FIGS. 1, 2 and 3, the blood cell counting mechanism 10 draws the washing liquid of the first washing liquid pool 211 through the liquid suction member 12 with a first liquid amount, the blood cell counting mechanism 10 draws the washing liquid of the second washing liquid pool 212 through the liquid suction member 12 with a second liquid amount, the blood cell counting mechanism 10 draws the washing liquid of the third washing liquid pool 213 through the liquid suction member 12 with a third liquid amount, the second liquid amount is greater than the first liquid amount, and the third liquid amount is greater than the second liquid amount.

[0082] According to some embodiments of the present application, the blood cell counting mechanism 10 is arranged to sequentially increase the liquid amount of the washing liquid sequentially drawn by the liquid suction member 12 from different washing liquid pools 21 according to the washing strength from high to low. By increasing the liquid amount of the washing liquid sequentially drawn by the liquid suction member 12 according to the washing strength from high to low, the washing liquid of the previous washing can be washed, the side wall of the inner cavity 111 is prevented from remaining the washing liquid of the previous washing, and the washing effect of the blood cell counting mechanism 10 is improved.

[0083] According to some embodiments of the present application, the POCT blood cell analyzer 1 performs self-checking on the blood cell counting mechanism 10, and selectively re-enters the maintenance mode or generates an alarm according to the self-checking result, i.e., after the third washing of the blood cell counting mechanism 10 is completed, the POCT blood cell analyzer 1 performs self-checking on the blood cell counting mechanism 10.

[0084] For example, after the third washing of the blood cell counting mechanism 10 is completed, the POCT blood cell analyzer 1 performs self-checking on the blood cell counting mechanism 10. In response to the self-checking result being failed, when the maintenance mode is selected to be re-entered, the blood cell counting mechanism 10 is re-maintained in the maintenance mode according to the maintenance mode of the above embodiments, which will not be described herein again. In response to the self-checking result being failed after the blood cell counting mechanism 10 is completed with the re-maintenance mode, the POCT blood cell analyzer 1 generates an alarm to remind the user to replace the microporous sheet 17 of the blood cell counting mechanism 10.

[0085] Optionally, after the microporous sheet 17 of the blood cell counting mechanism 10 is replaced, the blood cell counting mechanism 10 is re-entered into the maintenance mode.

[0086] ​Optionally, the self-checking of the blood cell counting mechanism 10 refers to establishing a negative pressure value preset pressure value in the inner cavity 111 of the main body 11, and sucking air or liquid by the liquid suction member 12 of the blood cell counting mechanism 10, reading the pressure value in the inner cavity 111 after an interval preset time, and calculating the difference between the preset pressure value and the pressure value. In response to the difference being within the preset range, the self-checking result is passed; in response to the difference not being within the preset range, the self-checking result is failed.

[0087] The POCT blood cell analyzer 1 of the embodiment performs self-checking on the blood cell counting mechanism 10, and selectively re-enters the maintenance mode or issues an alarm according to the self-checking result; the blood cell counting mechanism 10 can be self-checked to ensure that the blood cell counting mechanism 10 meets the detection conditions and improve the accuracy of the detection result of the POCT blood cell analyzer 1.

[0088] According to some embodiments of the present application, as shown in Figure 2 and Figure 5 , Figure 5 is a structural schematic diagram of a second embodiment of the POCT blood cell analyzer of the present application. The loading seat of the POCT blood cell analyzer 1 of the embodiment is also used to receive the loading of the detection reagent kit 30. The blood cell counting mechanism 10 of the POCT blood cell analyzer 1 of the embodiment is the same as the blood cell counting mechanism 10 of the above-mentioned embodiment, and will not be described here.

[0089] The POCT blood cell analyzer 1 of the present application includes two blood cell counting mechanisms 10 arranged side by side. In other embodiments, the POCT blood cell analyzer 1 can be provided with other numbers of blood cell counting mechanisms 10, for example, the POCT blood cell analyzer 1 includes one blood cell counting mechanism 10 or three blood cell counting mechanisms 10.

[0090] The blood cell counting mechanism 10 of the embodiment is provided with a detection mode. In the detection mode, the blood cell counting mechanism 10 sucks the detection liquid from the detection reagent kit 30 through the liquid suction member 12, and discharges the detection liquid in the main body 11 to the detection reagent kit 30 through the liquid discharge member 13.

[0091] For example, the detection kit 30 comprises a detection liquid pool 31, a detection cleaning liquid pool 32 and a detection waste liquid pool 33 arranged in sequence. In the detection mode, the suction member 12 is inserted into the detection liquid pool 31, and the discharge member 13 is inserted into the detection cleaning liquid pool 32, the blood cell counting mechanism 10 sucks the detection liquid from the detection liquid pool 31 through the suction member 12 to count the cell particles in the detection liquid; when the blood cell counting mechanism 10 completes the counting, the blood cell counting mechanism 10 can be moved relative to the detection kit 30, the suction member 12 is inserted into the detection cleaning liquid pool 32, and the discharge member 13 is inserted into the detection waste liquid pool 33, the blood cell counting mechanism 10 discharges the detection liquid in the main body 11 to the detection waste liquid pool 33 through the discharge member 13.

[0092] Alternatively, in the detection mode, the suction member 12 is inserted into the detection liquid pool 31, and the discharge member 13 is inserted into the detection liquid pool 31, the blood cell counting mechanism 10 sucks the detection liquid from the detection liquid pool 31 through the suction member 12 to count the cell particles in the detection liquid; when the blood cell counting mechanism 10 completes the counting, the blood cell counting mechanism 10 discharges the detection liquid in the main body 11 to the detection liquid pool 31 through the discharge member 13.

[0093] The blood cell counting mechanism 10 of the embodiment is provided with a detection mode, in which the blood cell counting mechanism 10 sucks the detection liquid from the detection kit 30 through the suction member 12 and discharges the detection liquid in the main body 11 to the detection kit 30 through the discharge member 13; the counting of the detection liquid can be realized.

[0094] According to some embodiments of the present application, referring to Figure 2 and Figure 5 the blood cell counting mechanism 10 of the embodiment also sucks the cleaning liquid from the detection kit 30 through the suction member 12 and discharges the cleaning liquid in the main body 11 to the detection kit 30 through the discharge member 13.

[0095] Alternatively, when the blood cell counting mechanism 10 completes the counting, the blood cell counting mechanism 10 can be moved relative to the detection kit 30, the suction member 12 is inserted into the detection cleaning liquid pool 32, and the discharge member 13 is inserted into the detection waste liquid pool 33, the blood cell counting mechanism 10 discharges the detection liquid in the main body 11 to the detection waste liquid pool 33 through the discharge member 13. The blood cell counting mechanism 10 also sucks the cleaning liquid from the detection cleaning liquid pool 32 through the suction member 12 to clean the inner cavity 111 of the main body 11, and discharges the cleaning liquid in the main body 11 to the detection waste liquid pool 33 through the discharge member 13.

[0096] Optionally, when the blood cell counting mechanism 10 completes counting, the blood cell counting mechanism 10 can be moved relative to the detection kit 30, the liquid suction member 12 is inserted into the detection cleaning liquid pool 32, the liquid discharge member 13 is inserted into the detection cleaning liquid pool 32, the blood cell counting mechanism 10 sucks the cleaning liquid from the detection cleaning liquid pool 32 through the liquid suction member 12 to clean the inner cavity 111 of the main body 11, and discharges the cleaning liquid in the main body 11 to the detection cleaning liquid pool 32 through the liquid discharge member 13. In other embodiments, the detection kit 30 can be provided only with the detection liquid pool 31 and the detection cleaning liquid pool 32 to suck or discharge the detection liquid in the detection liquid pool 31 and the cleaning liquid in the detection cleaning liquid pool 32.

[0097] The blood cell counting mechanism 10 of the embodiment also sucks the cleaning liquid from the detection kit 30 through the liquid suction member 12 and discharges the cleaning liquid in the main body 11 to the detection kit 30 through the liquid discharge member 13; the blood cell counting mechanism 10 can be cleaned after the blood cell counting mechanism 10 completes counting to reduce the pollution of the detection liquid and improve the accuracy of the detection result of the POCT blood cell analyzer 1.

[0098] Please refer to Figures 1 to 6 , Figure 6 is a flowchart of a first embodiment of a maintenance method of the POCT blood cell analyzer of the present application. The maintenance method of the embodiment is applied to the POCT blood cell analyzer 1 of the above-mentioned embodiments, and the maintenance method comprises the following steps:

[0099] S601: In response to the blood cell counting mechanism 10 in the maintenance mode, the maintenance kit 20 is loaded into the loading seat of the blood cell counting mechanism 10.

[0100] In response to the blood cell counting mechanism 10 in the maintenance mode, the maintenance kit 20 is loaded into the loading seat of the blood cell counting mechanism 10, and the loading seat receives the maintenance kit 20 so that the maintenance kit 20 is located in the housing. The maintenance kit 20 is the same as the maintenance kit 20 of the above-mentioned embodiments, and will not be described here.

[0101] In other embodiments, the maintenance kit 20 can be loaded into the loading seat of the blood cell counting mechanism 10 before the blood cell counting mechanism 10 is in the maintenance mode.

[0102] S602: The cleaning liquid is sucked from different cleaning liquid pools 21 through the liquid suction member 12 and is discharged from the main body 11 to the maintenance kit 20 through the liquid discharge member 13 in the order of high to low cleaning intensity.

[0103] The blood cell counting mechanism 10 is arranged to draw the cleaning liquid from the different cleaning liquid pools 21 through the liquid suction member 12 in descending order of the cleaning intensity, and discharge the cleaning liquid in the main body 11 to the maintenance reagent box 20 through the liquid discharge member 13. The same as the above embodiment, details are not repeated here.

[0104] S603: Self-checking the blood cell counting mechanism 10, and selectively re-entering the maintenance mode or alarming according to the self-checking result.

[0105] The blood cell counting mechanism 10 is self-checked to obtain a self-checking result. In response to the self-checking result failing, the maintenance mode is re-entered, and the step S602 is returned, details are not repeated here. In response to the self-checking result failing after the blood cell counting mechanism 10 completes the re-maintenance mode, the POCT blood cell analyzer 1 generates an alarm to remind the user to replace the micropore sheet 17 of the blood cell counting mechanism 10. In response to the self-checking result passing, the maintenance mode is ended.

[0106] The blood cell counting mechanism 10 is self-checked to obtain a self-checking result. In response to the self-checking result failing, the maintenance mode is re-entered, and the step S602 is returned, details are not repeated here. In response to the self-checking result failing after the blood cell counting mechanism 10 completes the re-maintenance mode, the POCT blood cell analyzer 1 generates an alarm to remind the user to replace the micropore sheet 17 of the blood cell counting mechanism 10. In response to the self-checking result passing, the maintenance mode is ended.

[0107] According to some embodiments of the present application, please refer to Figure 2 and Figure 9 , which are the structure schematic diagrams of the local amplification of the region A in the Figure 9 Figure 2 The main body 11 of the present embodiment is further provided with a front cavity 112, and the blood cell counting mechanism 10 further includes a micropore sheet 17, a first electrode 115, a second electrode 14, a liquid inlet hole 114, a liquid discharge hole 117, a pressure interface 116, and a switch valve 119.

[0108] The micropore sheet 17 is used to isolate the front cavity 112 and the inner cavity 111, and the micropore sheet 17 is provided with micropores 171, and the front cavity 112 and the inner cavity 111 are communicated through the micropores 171. The micropore sheet 17 can also be called a gemstone hole sheet, a gemstone sheet or a detection sheet, and the micropore 171 can also be called a gemstone hole or a detection hole. For example, the detection liquid in the front cavity 112 flows through the micropores 171 into the inner cavity 111 to allow the cells of the detection liquid to flow through the micropores 171 one by one.

[0109] Optionally, the liquid suction member 12, the front cavity 112, the micropore 171 and the liquid inlet hole 114 form the liquid suction channel of the present application, and the liquid discharge member 13, the switch valve 119 and the liquid discharge hole 117 form the liquid discharge channel of the present application.

[0110] ​The first electrode 115 is arranged in the inner cavity 111, that is, the free end of the first electrode 115 is located in the inner cavity 111, and the other end of the first electrode 115 is located outside the inner cavity 111; the first electrode 115 can also be referred to as a back cell electrode or a cathode.

[0111] Optionally, the free end of the first electrode 115 is electrically connected to the detection liquid in the inner cavity 111; the detection liquid flowing through the micropore 171 enters the inner cavity 111, and the free end of the first electrode 115 located in the inner cavity 111 is electrically connected to the detection liquid in the inner cavity 111, and the other end of the first electrode 115 located outside the inner cavity 111 is connected to the impedance detection circuit.

[0112] The second electrode 14 is arranged in the front cavity 112, and the second electrode 14 is electrically connected to the detection liquid in the front cavity 112.

[0113] Optionally, the bottom wall of the inner cavity 111 is arranged in an inclined manner, and along the direction of gravity, the side of the bottom wall of the inner cavity 111 close to the liquid suction member 12 (for example, the liquid inlet hole 114) is higher than the side of the bottom wall of the inner cavity 111 close to the liquid discharge member 13 (for example, the liquid discharge hole 117), so that the liquid in the inner cavity 111 flows to the side of the bottom wall of the inner cavity 111 close to the liquid discharge member 13, and then the liquid in the inner cavity 111 can be discharged from the liquid discharge member 13. The pressure interface 116 is arranged at the top of the inner cavity 111 to build pressure (positive pressure or negative pressure) in the inner cavity 111.

[0114] Please continue to refer to Figure 1 , Figure 2 and Figure 9 It is shown that the POCT blood cell analyzer 1 of the embodiment includes a shell, a loading seat and a blood cell counting mechanism 10. Among them, the blood cell counting mechanism 10 can also be referred to as a blood cell counting component or a blood cell counting cell.

[0115] The loading seat is used to receive the loading of the reagent box, and the reagent box is used to carry liquid; the blood cell counting mechanism 10 can move relative to the reagent box. Specifically, the blood cell counting mechanism 10 moves, and the reagent box does not move; or the blood cell counting mechanism 10 moves, and the reagent box moves; or the blood cell counting mechanism 10 does not move, and the reagent box moves.

[0116] The reagent box includes but is not limited to a maintenance reagent box 20, a detection reagent box 30 or other liquid-carrying reagent boxes. In other embodiments, the reagent box can also be replaced by other liquid-carrying objects, such as a reagent bottle used to carry liquid. The liquid carried by the reagent box includes but is not limited to cleaning liquid or detection liquid; the following describes the reagent box as the maintenance reagent box 20.

[0117] The blood cell counting mechanism 10 is disposed within the housing, and the loading seat is used to receive and load the maintenance reagent kit 20. For example, the loading seat is disposed within the housing. When the loading seat receives the maintenance reagent kit 20, the loading seat is moved out of the housing to place the maintenance reagent kit 20 on the loading seat. The maintenance reagent kit 20 is then moved into the housing, thereby enabling the loading seat to receive and load the maintenance reagent kit 20.

[0118] The blood cell counting mechanism 10 is movable relative to the maintenance reagent box 20. Specifically, the blood cell counting mechanism 10 moves and the maintenance reagent box 20 does not move; or the blood cell counting mechanism 10 moves and the maintenance reagent box 20 moves; or the blood cell counting mechanism 10 does not move and the maintenance reagent box 20 moves.

[0119] The blood cell counting mechanism 10 of this embodiment includes a main body 11, a liquid absorbing member 12, and a liquid discharging member 13. The liquid absorbing member 12 cooperates with the main body 11 to form a liquid absorbing channel for transferring liquid, and a microporous sheet 17 is disposed within the liquid absorbing channel. The liquid discharging member 13 cooperates with the main body 11 to form a liquid discharging channel for discharging liquid from the main body.

[0120] Optionally, the main body 11 is provided with an inner cavity 111, which is communicated with the liquid discharge channel and the liquid suction channel respectively. The inner cavity 111 can also be called a rear cavity or a rear pool.

[0121] When the aspiration channel is blocked, the blood cell counting mechanism 10 is configured to impact the aspiration channel with gas; or, to absorb liquid through the discharge member 13, that is, to absorb liquid from the maintenance reagent kit 20 through the discharge member 13 and impact the aspiration channel with the liquid.

[0122] The blockage in the liquid suction channel means that the microporous sheet 17 in the liquid suction channel is blocked or the liquid suction member 12 is blocked, so that the liquid suction channel is difficult to absorb liquid or cannot absorb liquid.

[0123] Specifically, when the aspiration channel is clogged, the blood cell counting mechanism 10 impacts the aspiration channel with gas. For example, when the aspiration channel is clogged, the drainage channel is controlled to be closed, and the inner cavity 111 of the main body 11 establishes a positive pressure to impact the aspiration channel with gas passing through the inner cavity 111.

[0124] Alternatively, when the suction passage is blocked, the blood cell counting mechanism 10 sucks liquid from the maintenance kit 20 through the liquid discharge member 13 and impacts the suction passage with the liquid. The free end of the liquid discharge member 13 of the blood cell counting mechanism 10 and the free end of the liquid suction member 12 are located below the liquid level of the liquid in the maintenance kit 20. For example, when the suction passage is blocked, the liquid discharge member 13 is inserted into the maintenance kit 20, the liquid discharge passage is controlled to be open, and the inner cavity 111 of the main body 11 is controlled to establish negative pressure to suck liquid from the maintenance kit 20 through the liquid discharge member 13; the liquid discharge passage is controlled to be closed, and the inner cavity 111 of the main body 11 is controlled to establish positive pressure to impact the suction passage with the liquid in the inner cavity 111.

[0125] When the suction passage is blocked, the blood cell counting mechanism 10 is configured to impact the suction passage with gas or liquid. The gas or liquid is used to impact the suction passage to enable the POCT blood cell analyzer 1 to handle the blockage of the suction passage, to solve the blockage of the suction passage with a high probability, and to improve the accuracy of the detection result of the POCT blood cell analyzer 1. In addition, the microporous sheet 17 of the blood cell counting mechanism 10 does not need to be frequently replaced, the service life of the microporous sheet 17 is delayed, and the cost is reduced. Furthermore, the POCT blood cell analyzer 1 does not need to increase other components, and the cost can be reduced.

[0126] According to some embodiments of the present application, as shown in Figure 1 and Figure 2 When the suction passage is blocked after the blood cell counting mechanism 10 impacts the suction passage with gas, the blood cell counting mechanism 10 is configured to suck liquid from the maintenance kit 20 through the liquid discharge member 13 and impact the suction passage with the liquid.

[0127] When the suction passage is blocked, the blood cell counting mechanism 10 is configured to impact the suction passage with gas. When the suction passage is still blocked after the blood cell counting mechanism 10 impacts the suction passage with gas, the blood cell counting mechanism 10 is configured to suck liquid from the maintenance kit 20 through the liquid discharge member 13 and impact the suction passage with the liquid.

[0128] When the suction passage is blocked after the blood cell counting mechanism 10 impacts the suction passage with gas, the blood cell counting mechanism 10 is configured to suck liquid from the maintenance kit 20 through the liquid discharge member 13 and impact the suction passage with the liquid. The suction passage is impacted twice with gas and liquid, which can improve the effect of impacting the suction passage and improve the accuracy of the detection result of the POCT blood cell analyzer 1. Furthermore, the POCT blood cell analyzer 1 does not need to increase other components, and the cost can be reduced.

[0129] According to some embodiments of the present application, the maintenance kit 20 of the present embodiments comprises a backflushing liquid pool for carrying liquid, and the blood cell counting mechanism 10 is configured to draw liquid from the backflushing liquid pool through the liquid discharge member 13 and to impact the liquid suction channel with the liquid through the liquid suction member 12.

[0130] When there is a blockage in the liquid suction channel, the blood cell counting mechanism 10 is configured to draw liquid from the backflushing liquid pool through the liquid discharge member 13 and to impact the liquid suction channel with the liquid through the liquid suction member 12. The present embodiments can improve the accuracy of the detection results of the POCT blood cell analyzer 1 by impacting the liquid suction channel with the liquid in the backflushing liquid pool. In addition, the POCT blood cell analyzer 1 does not need to increase other components, thereby reducing costs.

[0131] According to some embodiments of the present application, please refer to Figures 1-3 As shown in the figure, the maintenance kit 20 of the present embodiments comprises a plurality of cleaning liquid pools 21 for storing cleaning liquid with different cleaning strengths, and at least one of the plurality of cleaning liquid pools 21 is used as the backflushing liquid pool described above. For example, the plurality of cleaning liquid pools 21 are sequentially and adjacently arranged from high to low in cleaning strength, or the plurality of cleaning liquid pools 21 are randomly arranged; one of the plurality of cleaning liquid pools 21 is used as the backflushing liquid pool described above, or two of the plurality of cleaning liquid pools 21 are used as the backflushing liquid pool described above.

[0132] When there is a blockage in the liquid suction channel, the blood cell counting mechanism 10 is configured to draw cleaning liquid from at least one of the plurality of cleaning liquid pools 21 through the liquid discharge member 13 and to impact the liquid suction channel with the cleaning liquid.

[0133] For example, the blood cell counting mechanism 10 draws cleaning liquid with low cleaning strength from one of the cleaning liquid pools 21 of the maintenance kit 20 through the liquid discharge member 13 and impacts the liquid suction channel with the cleaning liquid with low cleaning strength. Alternatively, when there is a blockage in the liquid suction channel, the blood cell counting mechanism 10 draws cleaning liquid with high cleaning strength from another of the cleaning liquid pools 21 of the maintenance kit 20 through the liquid discharge member 13 and impacts the liquid suction channel with the cleaning liquid with high cleaning strength.

[0134] The present embodiments are configured to draw cleaning liquid from one of the plurality of cleaning liquid pools 21 through the liquid discharge member 13 and to impact the liquid suction channel with the cleaning liquid when there is a blockage in the liquid suction channel, so that the POCT blood cell analyzer 1 has the ability to handle blockage of the liquid suction channel and can solve the problem of blockage of the liquid suction channel with a high probability, thereby improving the accuracy of the detection results of the POCT blood cell analyzer 1.

[0135] According to some embodiments of the present application, the plurality of cleaning liquid pools 21 of the present embodiment includes a first cleaning liquid pool 211, a second cleaning liquid pool 212, and a third cleaning liquid pool 213, which are sequentially arranged along the extension direction of the maintenance kit 20.

[0136] The cleaning strength of the cleaning liquid in the first cleaning liquid pool 211 is greater than that of the cleaning liquid in the second cleaning liquid pool 212, and the cleaning strength of the cleaning liquid in the second cleaning liquid pool 212 is greater than or equal to that of the cleaning liquid in the third cleaning liquid pool 213.

[0137] For example, the cleaning liquid in the first cleaning liquid pool 211 is an alkaline strong cleaning liquid, the cleaning liquid in the second cleaning liquid pool 212 is a weak acid cleaning liquid, and the cleaning liquid in the third cleaning liquid pool 213 is pure water; or the cleaning liquid in the first cleaning liquid pool 211 is an alkaline strong cleaning liquid, the cleaning liquid in the second cleaning liquid pool 212 is pure water, and the cleaning liquid in the third cleaning liquid pool 213 is pure water.

[0138] The blood cell counting mechanism 10 is configured to draw the cleaning liquid from the third cleaning liquid pool 213, the second cleaning liquid pool 212, or the first cleaning liquid pool 211 through the liquid discharge member 13.

[0139] When there is a blockage in the liquid suction channel, the blood cell counting mechanism 10 draws the cleaning liquid from the third cleaning liquid pool 213 through the liquid discharge member 13, and the cleaning liquid in the third cleaning liquid pool 213 is used to impact the liquid suction channel, so that the third cleaning liquid pool 213 serves as a backflushing liquid pool. Alternatively, when there is a blockage in the liquid suction channel, the blood cell counting mechanism 10 draws the cleaning liquid from the second cleaning liquid pool 212 through the liquid discharge member 13, and the cleaning liquid in the second cleaning liquid pool 212 is used to impact the liquid suction channel, so that the second cleaning liquid pool 212 serves as a backflushing liquid pool. Alternatively, when there is a blockage in the liquid suction channel, the blood cell counting mechanism 10 draws the cleaning liquid from the first cleaning liquid pool 211 through the liquid discharge member 13, and the cleaning liquid in the first cleaning liquid pool 211 is used to impact the liquid suction channel, so that the first cleaning liquid pool 211 serves as a backflushing liquid pool.

[0140] The blood cell counting mechanism 10 of the present embodiment is configured to draw the cleaning liquid from the third cleaning liquid pool 213, the second cleaning liquid pool 212, or the first cleaning liquid pool 211 through the liquid discharge member 13. This enables the POCT blood cell analyzer 1 to have the ability to handle blockage of the liquid suction channel, and can solve the problem of blockage of the liquid suction channel with a high probability, thereby improving the accuracy of the detection results of the POCT blood cell analyzer 1.

[0141] According to some embodiments of the present application, the blood cell counting mechanism 10 of the present embodiment is configured to discharge the cleaning liquid in the main body 11 through the liquid suction member 12.

[0142] Specifically, the blood cell counting mechanism 10 sucks the cleaning liquid from the cleaning liquid pool 21 through the liquid discharging member 13 to impact the liquid suction channel with the cleaning liquid; and then discharges the cleaning liquid in the main body 11 to the cleaning liquid pool 21 through the liquid suction member 12 when the liquid suction channel is not blocked after the impact.

[0143] For example, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 to insert the liquid discharging member 13 into the third cleaning liquid pool 213, and then the liquid suction member 12 is inserted into the third cleaning liquid pool 213 to suck the cleaning liquid from the third cleaning liquid pool 213 through the liquid suction member 12 to impact the liquid suction channel when the liquid suction channel is blocked. When the liquid suction channel is not blocked after the impact, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 to insert the liquid discharging member 13 into the second cleaning liquid pool 212, and then the liquid suction member 12 is inserted into the third cleaning liquid pool 213, and the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the third cleaning liquid pool 213 through the liquid suction member 12.

[0144] Alternatively, the blood cell counting mechanism 10 sucks the cleaning liquid from the second cleaning liquid pool 212 through the liquid discharging member 13 to impact the liquid suction channel when the liquid suction channel is blocked. When the liquid suction channel is not blocked after the impact, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 to insert the liquid discharging member 13 into the first cleaning liquid pool 211, and then the liquid suction member 12 is inserted into the second cleaning liquid pool 212, and the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the second cleaning liquid pool 212 through the liquid suction member 12.

[0145] Alternatively, when the liquid discharging member 13 of the blood cell counting mechanism 10 is inserted into the third cleaning liquid pool 213, the liquid suction member 12 of the blood cell counting mechanism 10 is located outside the third cleaning liquid pool 213, for example, the liquid suction member 12 is located on the side of the third cleaning liquid pool 213 away from the second cleaning liquid pool 212.

[0146] In other embodiments, the liquid discharging member 13 and the liquid suction member 12 of the blood cell counting mechanism 10 are inserted into the same cleaning liquid pool 21. For example, the liquid discharging member 13 and the liquid suction member 12 of the blood cell counting mechanism 10 are inserted into the third cleaning liquid pool 213, and then the liquid suction member 12 is inserted into the third cleaning liquid pool 213 to suck the cleaning liquid from the third cleaning liquid pool 213 through the liquid suction member 12 to impact the liquid suction channel when the liquid suction channel is blocked. When the liquid suction channel is not blocked after the impact, the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the third cleaning liquid pool 213 through the liquid suction member 12.

[0147] The blood cell counting mechanism 10 of the present embodiment is configured to discharge the cleaning liquid in the main body 11 through the liquid suction member 12, which is simple to operate and improves the detection efficiency of the POCT blood cell analyzer 1.

[0148] According to some embodiments of the present application, when there is no blockage in the liquid suction channel after the impact, the blood cell counting mechanism 10 is arranged to draw the cleaning liquid from different cleaning liquid pools 21 by the liquid suction member 12 according to the cleaning intensity from high to low, and discharge the cleaning liquid in the main body 11 to the maintenance reagent box 20 by the liquid discharge member 13.

[0149] After the impact on the liquid suction channel is completed, there is no blockage in the liquid suction channel after the impact, and the blood cell counting mechanism 10 needs to be cleaned. For example, the blood cell counting mechanism 10 can be moved relative to the maintenance reagent box 20 to insert the liquid suction member 12 into the first cleaning liquid pool 211, and draw the cleaning liquid from the first cleaning liquid pool 211 by the liquid suction member 12; when the liquid suction member 12 completes the drawing of the cleaning liquid from the first cleaning liquid pool 211, the blood cell counting mechanism 10 can be moved relative to the maintenance reagent box 20 to insert the liquid suction member 12 into the second cleaning liquid pool 212, and insert the liquid discharge member 13 into the first cleaning liquid pool 211, and the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the first cleaning liquid pool 211 by the liquid discharge member 13, thereby completing the first cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 draws the cleaning liquid from the second cleaning liquid pool 212 by the liquid suction member 12; when the liquid suction member 12 completes the drawing of the cleaning liquid from the second cleaning liquid pool 212, the blood cell counting mechanism 10 can be moved relative to the maintenance reagent box 20 to insert the liquid suction member 12 into the third cleaning liquid pool 213, and insert the liquid discharge member 13 into the second cleaning liquid pool 212, and the blood cell counting mechanism 10 discharges the cleaning liquid in the main body 11 to the second cleaning liquid pool 212 by the liquid discharge member 13, thereby completing the second cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 draws the cleaning liquid from the third cleaning liquid pool 213 by the liquid suction member 12, and discharges the cleaning liquid in the main body 11 to the second cleaning liquid pool 212 by the liquid discharge member 13, or the blood cell counting mechanism 10 can be moved relative to the maintenance reagent box 20 to insert the liquid discharge member 13 into the third cleaning liquid pool 213, and discharge the cleaning liquid in the main body 11 to the third cleaning liquid pool 213 by the liquid discharge member 13, thereby completing the third cleaning of the blood cell counting mechanism 10.

[0150] Optionally, when the liquid suction member 12 of the blood cell counting mechanism 10 is inserted into the first cleaning liquid pool 211, the liquid discharge member 13 of the blood cell counting mechanism 10 is located outside the first cleaning liquid pool 211, for example, the liquid discharge member 13 is located on the side of the first cleaning liquid pool 211 away from the second cleaning liquid pool 212.

[0151] Optionally, the blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 and the liquid discharge member 13 are inserted into the first cleaning liquid pool 211, cleaning liquid is sucked from the first cleaning liquid pool 211 by the liquid suction member 12, and cleaning liquid in the main body 11 is discharged to the first cleaning liquid pool 211 by the liquid discharge member 13, thereby completing the first cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 and the liquid discharge member 13 are inserted into the second cleaning liquid pool 212, cleaning liquid is sucked from the second cleaning liquid pool 212 by the liquid suction member 12, and cleaning liquid in the main body 11 is discharged to the second cleaning liquid pool 212 by the liquid discharge member 13, thereby completing the second cleaning of the blood cell counting mechanism 10. The blood cell counting mechanism 10 can be moved relative to the maintenance kit 20 so that the liquid suction member 12 and the liquid discharge member 13 are inserted into the third cleaning liquid pool 213, cleaning liquid is sucked from the third cleaning liquid pool 213 by the liquid suction member 12, and cleaning liquid in the main body 11 is discharged to the third cleaning liquid pool 213 by the liquid discharge member 13, thereby completing the third cleaning of the blood cell counting mechanism 10.

[0152] In other embodiments, when there is no blockage in the liquid suction channel after the impact, the blood cell counting mechanism 10 is configured to suck cleaning liquid from different cleaning liquid pools 21 by the liquid discharge member 13 from high to low according to the cleaning strength, and discharge the cleaning liquid in the main body 11 to the maintenance kit 20 by the liquid suction member 12.

[0153] In this embodiment, when there is no blockage in the liquid suction channel after the impact, the blood cell counting mechanism 10 is configured to suck cleaning liquid from different cleaning liquid pools 21 by the liquid suction member 12 from high to low according to the cleaning strength, and discharge the cleaning liquid in the main body 11 to the maintenance kit 20 by the liquid discharge member 13. This achieves cleaning of the blood cell counting mechanism 10 after the impact, reduces waste liquid residue of the blood cell counting mechanism 10, and improves the accuracy of the detection results of the POCT blood cell analyzer 1.

[0154] According to some embodiments of the present application, please refer to Figure 1 、 Figure 2 and Figure 7 , Figure 7 is Figure 1 a structural schematic diagram of a third embodiment of a maintenance kit. The maintenance kit 20 of this embodiment further includes a second waste liquid pool 23 adjacent to the backflush liquid pool.

[0155] Specifically, the plurality of cleaning liquid pools 21 include a first cleaning liquid pool 211, a second cleaning liquid pool 212, and a third cleaning liquid pool 213, which are sequentially arranged along the extension direction of the maintenance kit 20. Among them, the cleaning strength of the cleaning liquid in the first cleaning liquid pool 211 is greater than that of the cleaning liquid in the second cleaning liquid pool 212, and the cleaning strength of the cleaning liquid in the second cleaning liquid pool 212 is greater than or equal to that of the cleaning liquid in the third cleaning liquid pool 213. Among them, the third cleaning liquid pool 213 is used as a backflushing liquid pool, and the second waste liquid pool 23 is arranged on the side of the third cleaning liquid pool 213 away from the second cleaning liquid pool 212.

[0156] When there is a blockage in the liquid suction channel, the blood cell counting mechanism 10 is arranged to suck liquid from the backflushing liquid pool through the liquid discharge member 13, and to impact the liquid suction channel with the liquid, and the second waste liquid pool 23 is used to contain the liquid suction member 12 and contain the liquid discharged by the impact.

[0157] When there is a blockage in the liquid suction channel, the liquid discharge member 13 is inserted into the third cleaning liquid pool 213 at the same time as the liquid suction member 12 is inserted into the second waste liquid pool 23, i.e. the cleaning liquid in the third cleaning liquid pool 213 is used as the liquid in the backflushing liquid pool, the third cleaning liquid pool 213 is used to contain the liquid discharge member 13, and the second waste liquid pool 23 is used to contain the liquid suction member 12; the blood cell counting mechanism 10 sucks the cleaning liquid in the third cleaning liquid pool 213 through the liquid discharge member 13 to impact the liquid suction channel with the cleaning liquid in the third cleaning liquid pool 213, and the cleaning liquid in the third cleaning liquid pool 213 is discharged to the second waste liquid pool 23 through the liquid suction member 12, i.e. the second waste liquid pool 23 is used to contain the liquid discharged by the impact.

[0158] When the blood cell counting mechanism 10 after the impact is cleaned, the blood cell counting mechanism 10 sucks the cleaning liquid in the third cleaning liquid pool 213 through the liquid discharge member 13 to clean the liquid suction channel with the cleaning liquid in the third cleaning liquid pool 213; and discharges the cleaning liquid in the main body 11 to the second waste liquid pool 23 through the liquid suction member 12.

[0159] Optionally, the spacing distance between the liquid suction member 12 and the liquid discharge member 13 is equal to the distance between the center axis of the second waste liquid pool 23 and the center axis of the third cleaning liquid pool 213, or the distance between the center axis of the third cleaning liquid pool 213 and the center axis of the second cleaning liquid pool 212, or the distance between the center axis of the second cleaning liquid pool 212 and the center axis of the first cleaning liquid pool 211.

[0160] When the liquid suction channel is blocked, the blood cell counting mechanism 10 is configured to draw liquid from the backflush liquid pool through the liquid discharge member 13, and to impact the liquid suction channel with the liquid, the second waste liquid pool 23 is configured to contain the liquid discharged by the impact, and the detection efficiency of the POCT blood cell analyzer 1 is improved; in addition, the second waste liquid pool 23 is configured to contain the liquid discharged by the impact, which can avoid contaminating the cleaning liquid pool 21 with the weakest cleaning strength (i.e., the third cleaning liquid pool 213), and the blood cell counting mechanism 10 after the impact can be cleaned by the cleaning liquid of the third cleaning liquid pool 213, reducing the waste liquid residue of the blood cell counting mechanism 10, and improving the accuracy of the detection results of the POCT blood cell analyzer 1.

[0161] Optionally, please refer to Figure 8 , Figure 8 is Figure 1 is a structural schematic diagram of a fourth embodiment of the maintenance kit. The maintenance kit 20 of the embodiment includes a second waste liquid pool 23 adjacent to the backflush liquid pool, and a first waste liquid pool 22 adjacent to the cleaning liquid pool 21 with the strongest cleaning strength.

[0162] The plurality of cleaning liquid pools 21 includes a first cleaning liquid pool 211, a second cleaning liquid pool 212, and a third cleaning liquid pool 213, which are sequentially arranged along the extension direction of the maintenance kit 20. Among them, the cleaning strength of the cleaning liquid of the first cleaning liquid pool 211 is greater than that of the cleaning liquid of the second cleaning liquid pool 212, and the cleaning strength of the cleaning liquid of the second cleaning liquid pool 212 is greater than or equal to that of the cleaning liquid of the third cleaning liquid pool 213. Among them, the third cleaning liquid pool 213 is used as a backflush liquid pool, the second waste liquid pool 23 is arranged on the side of the third cleaning liquid pool 213 away from the second cleaning liquid pool 212, and the first waste liquid pool 22 is arranged on the side of the first cleaning liquid pool 211 away from the second cleaning liquid pool 212.

[0163] The blood cell counting mechanism 10 is configured to insert the liquid suction member 12 into the cleaning liquid pool 21 with the strongest cleaning strength while inserting the liquid discharge member 13 into the first waste liquid pool 22. For example, in the maintenance mode, the blood cell counting mechanism 10 is configured to insert the liquid suction member 12 into the first cleaning liquid pool 211 while inserting the liquid discharge member 13 into the first waste liquid pool 22.

[0164] In other embodiments, the blood cell counting mechanism 10 can be configured to insert the liquid discharge member 13 into the first cleaning liquid pool 211 while inserting the liquid suction member 12 into the first waste liquid pool 22.

[0165] The maintenance kit 20 of the embodiment includes a second waste liquid pool 23 adjacent to the cleaning liquid pool 21 with the weakest cleaning intensity, and a first waste liquid pool 22 adjacent to the cleaning liquid pool 21 with the strongest cleaning intensity; the blood cell counting mechanism 10 can suck the cleaning liquid from the maintenance kit 20 through the liquid discharge member 13 when the liquid suction channel is blocked, and can suck the cleaning liquid from the maintenance kit 20 through the liquid suction member 12 or the liquid discharge member 13 in the maintenance mode, that is, the maintenance kit 20 can be applied to the maintenance mode and the scenario where the liquid suction channel is blocked, thereby reducing the cost.

[0166] Optionally, before the blood cell counting mechanism 10 sucks the liquid from the maintenance kit 20 through the liquid discharge member 13, the blood cell counting mechanism 10 performs the suction and exhaust cleaning on the liquid discharge member 13.

[0167] For example, when the liquid suction channel is blocked, the blood cell counting mechanism 10 performs the suction and exhaust cleaning on the liquid discharge member 13, and sucks the liquid from the maintenance kit 20 through the liquid discharge member 13.

[0168] The blood cell counting mechanism 10 of the embodiment performs the suction and exhaust cleaning on the liquid discharge member 13, which can prevent the pollution attached to the liquid discharge member 13 from entering the inner cavity 111 of the main body 11, reduce the pollution carried by the liquid discharge member 13, and improve the accuracy of the detection result of the POCT blood cell analyzer 1.

[0169] Optionally, along the extension direction of the liquid suction member 12, the spacing between the free end of the liquid suction member 12 and the free end of the liquid discharge member 13 is greater than or equal to one half of the depth of the cleaning liquid pool 21 of the maintenance kit 20, and less than or equal to two thirds of the depth of the cleaning liquid pool 21 of the maintenance kit 20.

[0170] The spacing between the free end of the liquid suction member 12 and the free end of the liquid discharge member 13 is greater than or equal to one half of the depth of the cleaning liquid pool 21 of the maintenance kit 20, and less than or equal to two thirds of the depth of the cleaning liquid pool 21 of the maintenance kit 20, so that the free end of the liquid discharge member 13 is located in the cleaning liquid pool 21 of the maintenance kit 20 to suck the cleaning liquid, and the liquid can be placed to prevent splashing to the maintenance kit 20 when the liquid is discharged from the free end of the liquid discharge member 13.

[0171] According to some embodiments of the present application, the blood cell counting mechanism 10 is provided with a maintenance mode, in which the blood cell counting mechanism 10 is configured to suck the cleaning liquid from different cleaning liquid pools 21 through the liquid suction member 12 in descending order of cleaning intensity, and discharge the cleaning liquid in the main body 11 to the maintenance kit 20 through the liquid discharge member 13. The blood cell counting mechanism 10 of the embodiment in the maintenance mode is the same as the maintenance mode of the above-mentioned embodiments, which will not be described here.

[0172] According to some embodiments of the present application, please refer to Figure 2 andFigure 5 As shown, the blood cell counting mechanism 10 is provided with a detection mode, and the loading seat is also used for receiving the detection reagent kit 30 to be loaded. In the detection mode, the blood cell counting mechanism 10 sucks the detection liquid from the detection reagent kit 30 through the liquid suction member 12, and discharges the detection liquid in the main body 11 to the detection reagent kit 30 through the liquid discharge member 13. The blood cell counting mechanism 10 of the embodiment in the detection mode is the same as the detection mode of the above-mentioned embodiments, and will not be described here again.

[0173] Optionally, the liquid discharge hole 117 is communicated with the liquid discharge member 13 through the on-off valve 119 to form a liquid discharge channel. When the liquid discharge member 13 sucks liquid from the maintenance reagent kit 20 or discharges liquid in the inner cavity 111, the on-off valve 119 is controlled to be turned on, at which time the inner cavity 111 is communicated with the liquid discharge hole 117, the on-off valve 119 and the liquid discharge member 13. When gas or liquid impacts the liquid suction channel, or the liquid suction member 12 sucks liquid, or the liquid suction member 12 discharges liquid in the inner cavity 111, the on-off valve 119 is controlled to be turned off, at which time the inner cavity 111 is not communicated with the liquid discharge member 13.

[0174] According to some embodiments of the present application, please refer to Figure 2 , Figure 9 , Figure 10 and Figure 11 , Figure 10 is a structural schematic diagram of a first embodiment of the pressure mechanism of the present application; Figure 11 is a structural schematic diagram of a second embodiment of the pressure mechanism of the present application. The POCT blood cell analyzer 1 of the embodiment further comprises a pressure mechanism 310, which is communicated with the pressure interface 116 and is used for building pressure in the inner cavity 111.

[0175] The pressure mechanism 310 comprises a pressure pump 311, a first on-off valve 312, a second on-off valve 313 and a three-way joint 314. The first end of the pressure pump 311 is connected with the first end of the three-way joint 314 through the first on-off valve 312, the second end of the pressure pump 311 is connected with the second end of the three-way joint 314 through the second on-off valve 313, and the third end of the three-way joint 314 is connected with the pressure interface 116.

[0176] As shown in Figure 10 , the first on-off valve 312 is controlled to be turned on, and the second on-off valve 313 is controlled to be turned off, at which time the pressure pump 311 is communicated with the blood cell counting mechanism 10 through the first on-off valve 312 to build negative pressure in the blood cell counting mechanism 10.

[0177] As shown in Figure 11 , the second on-off valve 313 is controlled to be turned on, and the first on-off valve 312 is controlled to be turned off, at which time the pressure pump 311 is communicated with the blood cell counting mechanism 10 through the second on-off valve 313 to build positive pressure in the blood cell counting mechanism 10.

[0178] The pressure mechanism 310 of the embodiment includes a pressure pump 311, a first switch valve 312, a second switch valve 313, and a three-way joint 314, and by controlling the first switch valve 312 and the second switch valve 313, a negative pressure or a positive pressure is established for the blood cell counting mechanism 10, which is simple in structure, easy to implement, and reduces the cost.

[0179] According to some embodiments of the present application, please refer to Figure 2 and Figure 9 The blood cell counting mechanism 10 further includes a quick release 100, which is detachably connected with the main body 11, and cooperates with the main body 11 to confine the microporous sheet 17 and the second electrode 14 in the front cavity 112. The quick release 100 and the main body 11 can be fixed by screws or buckles, etc.

[0180] When the microporous sheet 17 needs to be replaced, the quick release 100 is directly detached from the main body 11, and the liquid suction member 12, the second electrode 14, and the microporous sheet 17 are detached from the front cavity 112 to replace the microporous sheet 17. The updated microporous sheet 17, the second electrode 14, and the microporous sheet 17 are sequentially installed in the front cavity 112, and the quick release 100 is installed on the main body 11 to confine the microporous sheet 17 and the second electrode 14 in the front cavity 112.

[0181] The need to replace the microporous sheet 17 includes, but is not limited to, the need to replace the microporous sheet 17 when the liquid suction channel is still blocked after impact, or the blood cell counting mechanism 10 fails the self-check, or the POCT blood cell analyzer 1 generates an alarm to remind the replacement of the microporous sheet 17.

[0182] The blood cell counting mechanism 10 of the embodiment further includes a quick release 100, which is detachably connected with the main body 11; when the microporous sheet 17 needs to be replaced, the quick release 100 is directly detached from the main body 11 to replace the microporous sheet 17, without the need for professional operation, easy to operate, and reduces the cost.

[0183] According to some embodiments of the present application, please refer to Figure 2 and Figure 9 The blood cell counting mechanism 10 further includes a connecting member 18, a first sealing ring 15, a second sealing ring 19, and a third sealing ring 16.

[0184] The first sealing ring 15 is arranged between the main body 11 and the microporous sheet 17, and is used to seal the gap between the microporous sheet 17 and the main body 11. The third sealing ring 16 is arranged between the second electrode 14 and the microporous sheet 17 to seal the second electrode 14 and the microporous sheet 17.

[0185] The second electrode 14 is provided with a first through hole 141 along the axial direction of the micropores 171, the first through hole 141 comprising a first hole section 142, a second hole section 143 and a third hole section 145, the first hole section 142 being arranged close to the micropore sheet 17 relative to the second hole section 143; the inner diameter of the first hole section 142 is smaller than that of the second hole section 143, thereby forming an annular mesa 144 at the joint of the second hole section 143 and the first hole section 142. The third hole section 145 is arranged close to the micropore sheet 17 relative to the first hole section 142; the inner diameter of the first hole section 142 is smaller than that of the third hole section 145. The micropore sheet 17, the third sealing ring 16 and the third hole section 145 of the second electrode 14 form the front cavity 112.

[0186] The second sealing ring 19 is clamped between the end face of the liquid suction member 12 and the annular mesa 144, and abuts against the side peripheral wall of the second hole section 143.

[0187] The main body 11 is provided with a through hole 118, and the connecting member 18 is arranged through the through hole 118, the connecting member 18 being used for electrically connecting with the second electrode 14, so that the impedance detection circuit supplies power to the second electrode 14 through the connecting member 18.

[0188] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present application, and not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement to part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should be covered in the scope of the claims and the description of the present application. Especially, as long as there is no structural conflict, each technical feature mentioned in each embodiment can be combined in any way. The present application is not limited to the specific embodiments disclosed in the text, but includes all technical solutions falling within the scope of the claims.

Claims

1. A POCT blood cell analyzer, characterized in that: include: case; A loading seat, used for receiving the reagent kit; a blood cell counting mechanism, disposed in the housing, and movable relative to the reagent box; The blood cell counting mechanism comprises: main body; A liquid absorbing member, the liquid absorbing member cooperates with the main body to form a liquid absorbing channel for conveying liquid; a microporous sheet is provided in the liquid absorbing channel; a liquid discharge member, the liquid discharge member cooperates with the main body to form a liquid discharge channel for discharging liquid from the main body; When the aspiration channel is clogged, the blood cell counting mechanism is configured to impact the aspiration channel through the gas in the main body, or to absorb liquid through the discharge member and impact the aspiration channel through the liquid.

2. The POCT blood cell analyzer according to claim 1, characterized in that: After the gas impacts the liquid aspiration channel and when the liquid aspiration channel is blocked, the blood cell counting mechanism is configured to absorb liquid through the liquid discharge member and impact the liquid aspiration channel with the liquid.

3. The POCT blood cell analyzer according to claim 1 or 2, characterized in that: The loading seat is also used to receive a maintenance kit, and the blood cell counting mechanism can move relative to the maintenance kit; The blood cell counting mechanism is configured to absorb liquid from the maintenance reagent kit through the liquid discharge member and to impact the liquid aspiration channel with the liquid.

4. The POCT blood cell analyzer according to claim 3, characterized in that: The maintenance kit includes a backflushing liquid pool for storing liquid. The blood cell counting mechanism is configured to absorb liquid from the backflushing liquid pool through the liquid discharge member and impact the liquid aspiration channel with the liquid.

5. The POCT blood cell analyzer according to claim 3, characterized in that: The maintenance kit includes multiple cleaning liquid pools, which are used to store cleaning liquids of different cleaning strengths; at least one of the multiple cleaning liquid pools is used as a backflushing liquid pool, and when the aspiration channel is blocked, the blood cell counting mechanism is configured to absorb the cleaning liquid from at least one of the multiple cleaning liquid pools through the discharge member, and impact the aspiration channel with the cleaning liquid.

6. The POCT blood cell analyzer according to claim 4 or 5, characterized in that: The maintenance kit further includes a second waste liquid pool disposed adjacent to the backflushing liquid pool. When the aspiration channel is clogged, the blood cell counting mechanism is configured to aspirate liquid from the backflushing liquid pool via the liquid discharging member and impact the aspiration channel with the liquid. The second waste liquid pool is configured to accommodate the liquid aspirating member and the liquid discharged by the impact.

7. The POCT blood cell analyzer according to claim 5, characterized in that: When there is no blockage in the suction channel after the impact, the blood cell counting mechanism is configured to absorb the cleaning liquid from different cleaning liquid pools through the suction component according to the cleaning intensity from high to low, and discharge the cleaning liquid in the main body into the maintenance kit through the discharge component.

8. The POCT blood cell analyzer according to claim 7, characterized in that: The maintenance kit further includes a first waste liquid pool adjacent to the cleaning liquid pool with the strongest cleaning intensity. The blood cell counting mechanism is configured to insert the liquid suction piece into the cleaning liquid pool with the strongest cleaning intensity while inserting the liquid discharge piece into the first waste liquid pool.

9. The POCT blood cell analyzer according to claim 1, characterized in that: The blood cell counting mechanism also includes a switch valve. The main body is provided with a drainage hole. The drainage member is connected to the drainage hole through the switch valve to form the drainage channel. When the drainage member absorbs liquid, the switch valve is controlled to be open. When the gas or the liquid impacts the liquid absorption channel, the switch valve is controlled to be closed.

10. The POCT blood cell analyzer according to claim 1, characterized in that: The blood cell counting mechanism is provided with a detection mode, the loading seat is further used to receive the detection kit, and the blood cell counting mechanism can move relative to the detection kit; In the detection mode, the blood cell counting mechanism absorbs the detection liquid from the detection reagent kit through the liquid absorbing member, and discharges the detection liquid in the main body into the detection reagent kit through the liquid discharging member.

Images