Efficient anti-aging composition and skin care product containing same

Abstract

The invention relates to the technical field of cosmetics, in particular to an efficient anti-aging composition and a skin care product containing the composition. The invention discloses an efficient anti-aging composition which is prepared from the following raw materials in parts by mass: 12-15 parts of oil-based concentrated active ingredients, 25-35 parts of base collagen liquid, 15-18 parts of Ectoine, 12-16 parts of TWEEN 20 and 22-25 parts of isosorbide dimethyl ether, and the oil-based concentrated active ingredients are prepared from safflower seed oil, an extract of flowers / leaves / stems of herba lysimachiae, an extract of radix astragali membranaci, ubiquinone and vitamin E; the base collagen liquid comprises XVII type collagen, VII type collagen and IV type collagen. Aiming at the problems that an existing skin care product cannot effectively reduce skin wrinkles, improve skin compactness, reduce skin sagging and prevent skin aging for a long time, the composition disclosed by the invention realizes long-term aging resistance from epidermis to dermis, effectively reduces wrinkles, improves compactness and improves skin sagging.

Description

Technical Field

[0001] This application relates to the field of cosmetic technology, and more particularly to a highly effective anti-aging composition and a skin care product containing the composition. Background Art

[0002] Skin aging arises from the synergistic effect of endogenous aging and exogenous stimuli, and its manifestations are directly related to the degeneration of the structure and function of the epidermis, dermis, and connective tissue. At the endogenous level, with age, fibroblast activity decreases, leading to a loosening of the connective tissue structure, weakening the mechanical connection between the epidermis and dermis, and reducing the skin's resistance to traction. Simultaneously, an imbalance in free radical metabolism causes collagen cross-linking or breakage, disintegrating the dermal support network, resulting in decreased skin elasticity and sagging. Among exogenous factors, inflammatory factors induced by ultraviolet radiation accelerate collagen degradation, while abnormal release of acetylcholine at the neuromuscular junction causes excessive muscle contraction, initially forming dynamic wrinkles, which, under long-term traction, irreversibly damage collagen and transform into static wrinkles. Furthermore, the epidermal barrier is damaged by free radical oxidation of the lipid bilayer, reducing its water-locking capacity. This, coupled with slowed keratin metabolism, leads to dry and dull skin, forming a chain reaction from structural damage to functional decline. The main external manifestations are sagging skin, loss of elasticity, pigmentation, dull skin tone, enlarged pores, and the appearance and deepening of wrinkles.

[0003] Existing anti-aging technologies have significant shortcomings. First, their efficacy is limited. For example, peony root extract focuses on anti-oxidation, and retinol promotes the differentiation of skin keratinocytes, but neither can comprehensively combat photoaging, glycation, and other multi-pathway aging mechanisms. Second, some products contain chemical ingredients that have certain toxic side effects on the human body. Long-term overuse can damage the skin barrier function, causing sensitive skin. This results in a disconnect between the improvement of dynamic and static wrinkles. Immediate anti-wrinkle ingredients only temporarily relieve muscle contraction, and neglecting the repair of the DEJ layer makes it difficult for anti-wrinkle ingredients to penetrate the dermal network. This leads to the epidermis losing support and the dermal nutrient delivery being hindered, greatly reducing the repair effect. Consequently, anti-wrinkle products are either slow to take effect or have short-lasting effects, resulting in poor anti-aging results. Summary of the Invention

[0004] In response to the problem that existing skincare products cannot effectively reduce skin wrinkles, improve skin firmness, reduce skin sagging, and prevent skin aging in the long term, this application provides a highly effective anti-aging composition and a skincare product containing the composition.

[0005] In a first aspect, this application provides a highly effective anti-aging composition, employing the following technical solution: A highly effective anti-aging composition is made from the following raw materials in parts by weight: 12-15 parts of oil-based concentrated active ingredients, 25-35 parts of base collagen solution, 15-18 parts of ectoine, 12-16 parts of TWEEN 20, and 22-25 parts of isosorbide dimethyl ether. The oil-based concentrated active ingredients are safflower seed oil, extracts of golden button flower / leaf / stem, extract of Astragalus membranaceus root, ubiquinone, and vitamin E. The base collagen solution includes type XVII collagen, type VII collagen, and type IV collagen.

[0006] The highly effective anti-aging composition of this application achieves long-term wrinkle reduction, improved firmness, and reduced sagging through the interaction of multiple components in the epidermis, epidermal-dermal junction (DEJ layer), and dermis. As the outermost barrier of the skin, the stability of the connection between the epidermis and dermis directly determines the skin's tensile strength and nutrient exchange efficiency. The interaction of type XVII, VII, and IV collagen contained in the base collagen solution strengthens the basic support of the epidermis, DEJ layer, and dermis, preventing insufficient support of the basal layer from causing epidermal laxity, thereby improving deep static wrinkles caused by facial contour sagging due to insufficient epidermal elasticity. Type XVII collagen, as a transmembrane protein, can bind to integrins and load into hemidesmosomes. Hemidesmosomes, as anchoring structures, have their transmembrane regions tightly bound to laminocytes and embedded in the cell membranes of epidermal basal cells, strengthening the tight connection between the epidermis and dermis. Furthermore, the extracellular region extends a specific binding site, the α-helix region, which binds to the NC of type VII collagen. The β-sheet regions of the 1-terminal domains are spatially complementary, allowing for precise intercalation and docking. Furthermore, the interaction between their peptide chains and integrins ensures that the epidermis does not separate from the dermis due to mechanical traction. Type VII collagen, acting as a mechanically conductive fiber, spans the DEJ layer with its long chain structure. Its NC2 end is embedded in the basement membrane network formed by type IV collagen, uniformly transmitting dynamic tension from the epidermis to the dermis and preventing collagen breakage caused by localized stress concentration. Type IV collagen, through its triple helix structure and interwoven with laminin, forms a dense basement membrane network, providing stable attachment points for type VII collagen and regulating the transport of growth factors secreted by fibroblasts in the dermis to the epidermis through the network pores. This ensures the proliferation and differentiation of epidermal keratinocytes and maintains the integrity of the epidermal barrier. The interaction of these three elements results in a compact DEJ layer structure, strengthening the connection and support between the epidermis and dermis, slowing wrinkle formation in the long term, and improving skin sagging.

[0007] Based on this, the extracts of golden button flower / leaf / stem in the concentrated active ingredients of the oil base can block the voltage-gated sodium ion channels at the neuromuscular junction, reduce the release of acetylcholine, and immediately relieve the dynamic tension caused by excessive muscle contraction, reducing the mechanical traction on the DEJ layer. This can create a low-damage environment for the connection structure of the three repair collagens in the base collagen solution. Astragalus membranaceus root extract can directly stimulate fibroblasts in the dermis, promote the synthesis of type I collagen, and enhance the mechanical support of the dermis. Together with the three collagens in the base collagen solution, it can enhance the repair of the DEJ layer and reduce the stress load on the DEJ layer. The stability of the DEJ layer can effectively transfer the support of the dermis to the epidermis, thus improving skin sagging and static wrinkles. The antioxidant system composed of ubiquinone and vitamin E can specifically eliminate reactive oxygen free radicals generated by exogenous stimuli such as ultraviolet rays, reduce their oxidative damage to the thiol groups of type XVII collagen, the peptide bonds of type VII collagen, and the hydroxyl groups of type IV collagen, and protect the structural integrity of the DEJ layer.

[0008] Ectoin inhibits the release of inflammatory factors such as tumor necrosis factor-α and interleukin-6, reduces the production of matrix metalloproteinases, and prevents their activity in degrading type VII collagen. This avoids the enzymatic destruction of collagen and enhances the stability of antioxidants in the oil-based components. In addition, TWEEN 20 and isosorbide dimethyl ether, as a penetration-enhancing system, ensure that the concentrated active ingredients in the oil-based system penetrate the stratum corneum and the base collagen solution to reach the DEJ layer and dermis. This achieves a precise combination of epidermal barrier maintenance, DEJ layer structural repair, and dermal support strengthening, ultimately achieving long-term anti-aging from the epidermis to the dermis, effectively reducing wrinkles, improving firmness, and improving skin sagging.

[0009] The mass ratio of the oil-based concentrated active ingredient, the base collagen solution, and ectoine is 1:(1.5-2):(0.8-1.5).

[0010] Based on the effects of the aforementioned effective components, the inventors further explored the influence of the proportions of each effective component. The concentrated active ingredients in the oil base instantly soothe dynamic wrinkles and reduce oxidative damage, creating a stable environment for the base collagen solution to repair the DEJ layer and dermal collagen; they also help the base collagen solution rebuild the epidermal-dermal connection and support structure, enhancing the structural basis for the oil-based components' effects. Ectoin inhibits the degradation of both by inflammatory factors, prolonging its duration of action. This achieves both instant relief of dynamic wrinkles and long-term beneficial effects such as reduced static wrinkles, improved firmness, and improved sagging by enhancing the structural support of the DEJ layer and dermis. Excessive base collagen solution can lead to insufficient immediate regulatory capacity of the oil-based components, resulting in slower soothing of dynamic wrinkles and increased mechanical tension during collagen repair, thus slowing down fine line repair. Insufficient base collagen solution results in inadequate collagen replenishment, leaving the improved state of the oil-based components without sufficient structural support, leading to a short-lasting effect. Insufficient ectoin weakens the inhibition of inflammatory factors, accelerates the oxidative depletion of the oil-based components, and slows down the improvement of dull skin tone.

[0011] The mass ratio of type XVII collagen, type VII collagen, and type IV collagen is 1:(1.5-2):(2.4-3.2).

[0012] The inventors discovered that, at the aforementioned mass ratio, type XVII, type VII, and type IV collagen can effectively strengthen and thus achieve the structural integrity and mechanical stability of the epidermis, DEJ layer, and dermis. Analysis suggests that an excess of type VII collagen may cause its long-chain structures to cross-link with each other, forming abnormal fiber bundles that block the pores of the type IV collagen network. This hinders the transfer of nutrients from the dermis to the epidermis, leading to a decrease in epidermal metabolic rate, minimal improvement in skin dullness, weakened barrier function, and poor short-term anti-wrinkle effects. Conversely, an excess of type VII collagen results in insufficient connection strength, making it difficult for the anchoring signal of type XVII collagen to be effectively transmitted to the basement membrane. This reduces the dynamic tension buffering capacity, making the epidermis prone to separation from the dermis due to external traction, slowing down the improvement of skin sagging, and worsening the anti-aging effect. An excess of type IV collagen leads to a weak supporting framework, lacking a stable fulcrum for the tension transmission of type VII collagen, reducing the overall tensile strength of the connecting layer, and affecting the repair efficiency of deep static wrinkles.

[0013] The highly effective anti-aging composition further includes 5-8 parts of anti-aging components, which include one or more of the following: acetyl hexapeptide-8, acetyl hexapeptide-1, ascorbic acid tetraisopalmitate, boswellia, vitamin C ethyl ether, alfalfa extract, cornflower extract, chrysanthemum extract, chicory root extract, and sacha inchi oil.

[0014] Preferably, the anti-aging components are chicory root extract and Inca Inchi oil in a mass ratio of 1:(4-6).

[0015] By employing the above-mentioned technical solutions, chicory root extract can stimulate fibroblast activity, promote endogenous collagen synthesis, further strengthen dermal support, and enhance skin elasticity. Combined with Inca Inchi oil, which is rich in unsaturated fatty acids, it repairs the epidermal lipid barrier, reduces moisture loss, improves dullness, and enhances skin radiance. Simultaneously, the fat-soluble properties of Inca Inchi oil encapsulate the chicory root extract, allowing it to penetrate the dermis, strengthening dermal support, and improving firmness and elasticity. Both, based on different mechanisms, work together to effectively improve skin elasticity and maintain firmness. Furthermore, the anti-aging components work synergistically with safflower seed oil. On one hand, the omega-3 and omega-6 fatty acids in safflower seed oil regulate inflammatory factors, reducing the damage to collagen caused by L-6 and TNF-α, providing a more stable environment for the chicory root extract to stimulate fibroblast collagen synthesis and improve firmness and elasticity. On the other hand, the linoleic acid in safflower seed oil and the unsaturated fatty acids in Inca Inchi oil work together to stabilize the lipid bilayer, enhance water retention, and reduce dullness caused by dryness. Low levels of Sacha Inchi oil lead to insufficient repair of the epidermal lipid barrier, weakened skin's ability to retain moisture, and reduced effectiveness in improving dullness. The transdermal efficiency of safflower seed oil and chicory root extract is also affected, resulting in reduced regulation of inflammatory factors and a decrease in the overall repair efficiency for elasticity and firmness.

[0016] Secondly, this application provides a skincare product, which is one of an anti-aging serum and a skincare cream. The skincare product comprises the highly effective anti-aging composition provided in the first aspect.

[0017] Furthermore, the anti-aging serum includes a highly effective anti-aging composition, wherein the highly effective anti-aging composition has a mass percentage content of 2-10%.

[0018] The anti-aging essence is also made from the following ingredients by weight percentage: 1,3-butanediol 3-10%, TR-2 0.1-0.3%, arginine 0.1-0.3%, 1,2-hexanediol 0.5-0.8%, p-hydroxyacetophenone 0.3-0.6%, with the balance being water.

[0019] In summary, this application has the following beneficial effects: 1. The highly effective anti-aging composition of this application achieves long-term wrinkle reduction, improved firmness, and reduced sagging through the interaction of multiple components in the epidermis, epidermal-dermal junction (DEJ layer), and dermis. First, the interaction of type XVII, type VII, and type IV collagen contained in the base collagen solution strengthens the basic support of the epidermis, DEJ layer, and dermis. The concentrated active ingredients in the oil base instantly soothe dynamic wrinkles and reduce oxidative damage, creating a stable structural foundation for the base collagen solution to repair the DEJ layer and dermal collagen. Ectoin inhibits the degradation of both by inflammatory factors, prolonging its duration of action. This achieves immediate relief of dynamic wrinkles and, by enhancing the structural support of the DEJ layer and dermis, long-term beneficial effects such as reduced static wrinkles, improved firmness, and reduced sagging.

[0020] 2. By using chicory root extract to help rebuild the epidermal-dermal connection and support structure of the base collagen solution, and enhancing the activity of fibroblasts by the oil-based components, promoting endogenous collagen synthesis, and further strengthening dermal support and enhancing skin elasticity, the addition of Inca Inchi oil, rich in unsaturated fatty acids, repairs the epidermal lipid barrier, reduces moisture loss, improves dullness, and enhances epidermal radiance. At the same time, the fat-soluble properties of Inca Inchi oil encapsulate the chicory root extract to penetrate the dermis, strengthen dermal support, and improve firmness and elasticity. Detailed Implementation

[0021] The present application will be further described in detail below with reference to the embodiments.

[0022] Some of the raw materials used in the preparation examples and embodiments: the oil-based concentrated active ingredient, commercially known as LIFT Oléoactif, was purchased from HALLSTAR, and its components are safflower seed oil, golden button flower / leaf / stem extract, Astragalus membranaceus root extract, ubiquinone, and vitamin E; ectoine was purchased from Guangzhou Shengrui Chemical Technology Co., Ltd.; TWEEN 20 was purchased from Heda; type XVII collagen was prepared as a 100 g / L solution of type XVII collagen, purchased from Jiangsu Jinpu Nuoan Biotechnology Co., Ltd.; type VII collagen was prepared as a solution of type VII collagen, purchased from Shanghai Yaji Biotechnology Co., Ltd.; type IV collagen was prepared as a solution of type IV collagen, both purchased from Shanghai Yuanmu Biotechnology Co., Ltd.; chicory root extract was purchased from Shaanxi Haochen Biotechnology Co., Ltd.; Inca Inchi oil was purchased from Xuzhou Yihuiyang New Materials Co., Ltd.; TR-2 is carbomer; unless otherwise specified, all raw materials used in the embodiments and comparative examples are conventional products that can be purchased commercially. Example 1

[0023] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 15 parts of ectoine, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3. TWEEN 20, base collagen solution, and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 2

[0024] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 33 parts of base collagen solution, 12 parts of ectoine, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3. TWEEN 20, base collagen solution, and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 3

[0025] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 25 parts of base collagen solution, 20 parts of ectoine, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3. TWEEN 20, base collagen solution, and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 4

[0026] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 20 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 10 parts of ectoine, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3. TWEEN 20, base collagen solution, and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 5

[0027] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 15 parts of ectoine, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2.5:2.5. TWEEN 20, base collagen solution, and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 6

[0028] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 15 parts of ectoine, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:1:4. TWEEN 20, base collagen solution, and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 7

[0029] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 15 parts of ectoine, 8 parts of anti-aging components, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3; the anti-aging components are chicory root extract and Inca Inchi oil in a mass ratio of 1:6. TWEEN 20, base collagen solution, and ectoine were mixed in proportion and stirred at 45°C to dissolve. Isosorbide dimethyl ether was added and stirred evenly. Oil-based concentrated active ingredients were added and the anti-aging components were stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 8

[0030] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 15 parts of ectoine, 8 parts of anti-aging components, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether; the base collagen solution is type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3; the anti-aging components are chicory root extract and Inca Inchi oil in a mass ratio of 1:3. TWEEN 20, base collagen solution, and ectoine were mixed in proportion and stirred at 45°C to dissolve. Isosorbide dimethyl ether was added and stirred evenly. Oil-based concentrated active ingredients were added and the anti-aging components were stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 9

[0031] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 15 parts of ectoine, 8 parts of chicory root extract, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether. The oil-based concentrated active ingredients are safflower seed oil, golden button flower / leaf / stem extract, Astragalus membranaceus root extract, ubiquinone, and vitamin E. The base collagen solution is composed of type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3. TWEEN 20, base collagen solution, and ectoine were mixed in proportion and stirred at 45°C to dissolve. Isosorbide dimethyl ether was added and stirred evenly. Oil-based concentrated active ingredients and chicory root extract were added and stirred at high speed for 5 minutes, then cooled to room temperature to obtain a highly effective anti-aging composition. Example 10

[0032] A highly effective anti-aging composition is made from the following raw materials in parts by weight: 15 parts of oil-based concentrated active ingredients, 30 parts of base collagen solution, 15 parts of ectoine, 8 parts of Inca Inchi oil, 15 parts of TWEEN 20, and 25 parts of isosorbide dimethyl ether. The oil-based concentrated active ingredients are safflower seed oil, extracts of golden button flower / leaf / stem, extract of Astragalus membranaceus root, ubiquinone, and vitamin E. The base collagen solution is composed of type XVII collagen, type VII collagen, and type IV collagen in a mass ratio of 1:2:3. TWEEN 20, base collagen solution, and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and Inca Inchi oil was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a highly effective anti-aging composition. Example 11

[0033] An anti-aging serum is made from the following ingredients in weight percentages: 5% 1,3-butanediol, 0.2% TR-2, 0.2% arginine, 0.5% 1,2-hexanediol, 0.5% p-hydroxyacetophenone, and 10% of the highly effective anti-aging composition prepared in Example 1. The balance is water.

[0034] Add half of the water, butanediol, TR-2, 1,2-hexanediol, and p-hydroxyacetophenone in sequence according to the ratio, heat to 80°C and stir to disperse evenly. Then add the solution of arginine and the other half of the water, cool to 40°C, add the high-efficiency anti-aging composition prepared in Example 1 and stir evenly to obtain the anti-aging essence. Example 12

[0035] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 1 is replaced by an equal amount of the high-efficiency anti-aging composition of Embodiment 2. Example 13

[0036] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 1 is replaced by an equal amount of the high-efficiency anti-aging composition of Embodiment 3. Example 14

[0037] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 4 is used to replace the high-efficiency anti-aging composition of Embodiment 1 in an equal amount. Example 15

[0038] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 1 is replaced by an equal amount of the high-efficiency anti-aging composition of Embodiment 5. Example 16

[0039] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 1 is replaced by an equal amount of the high-efficiency anti-aging composition of Embodiment 6. Example 17

[0040] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 7 is used to replace the high-efficiency anti-aging composition of Embodiment 1 in an equal amount. Example 18

[0041] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 1 is replaced by an equal amount of the high-efficiency anti-aging composition of Embodiment 8. Example 19

[0042] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 1 is replaced by an equal amount of the high-efficiency anti-aging composition of Embodiment 9. Example 20

[0043] The only difference between this embodiment and Embodiment 11 is that the high-efficiency anti-aging composition of Embodiment 1 is replaced by an equal amount of the high-efficiency anti-aging composition of Embodiment 10.

[0044] Comparative Example 1 An anti-aging serum is made from the following ingredients in the indicated weight percentages: 1,3-butanediol 5%, TR-2 0.2%, arginine 0.2%, 1,2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, a high-efficiency anti-aging composition 10%, and the balance being water. The high-efficiency anti-aging composition is made from the following ingredients in the indicated weight percentages: 15 parts oil-based concentrated active ingredients, 30 parts base collagen solution, 15 parts ectoine, 15 parts TWEEN 20, and 25 parts isosorbide dimethyl ether; the base collagen solution is type XVII collagen and type IV collagen in a weight ratio of 1:5. Preparation of a high-efficiency anti-aging composition: TWEEN 20, base collagen solution and ectoine are mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether is added and stirred evenly, oil-based concentrated active ingredients are added, stirred at high speed for 5 minutes and then cooled to room temperature to obtain a high-efficiency anti-aging composition.

[0045] Preparation of anti-aging essence: Add half water, butylene glycol, TR-2, 1,2-hexanediol and p-hydroxyacetophenone in sequence according to the ratio, heat to 80°C and stir to disperse evenly, then add arginine and the other half water solution, cool to 40°C, add the high-efficiency anti-aging composition and stir evenly to obtain anti-aging essence.

[0046] Comparative Example 2 The only difference between this comparative example and Comparative Example 1 is that the base collagen solution is type XVII collagen and type VII collagen with a mass ratio of 1:5.

[0047] Comparative Example 3 The only difference between this comparative example and Comparative Example 1 is that the base collagen solution is type VII collagen and type IV collagen with a mass ratio of 1:1.

[0048] Comparative Example 4 The only difference between this comparative example and Comparative Example 1 is that the base collagen solution is type XVII collagen.

[0049] Comparative Example 5 The only difference between this comparative example and Comparative Example 1 is that the base collagen solution is type VII collagen.

[0050] Comparative Example 6 The only difference between this comparative example and Comparative Example 1 is that the base collagen solution is type IV collagen.

[0051] Comparative Example 7 An anti-aging serum is made from the following ingredients in the indicated weight percentages: 1,3-butanediol 5%, TR-2 0.2%, arginine 0.2%, 1,2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, a high-efficiency anti-aging composition 10%, and the balance being water. The high-efficiency anti-aging composition is made from the following ingredients in the indicated weight percentages: 15 parts oil-based concentrated active ingredients, 30 parts base collagen solution, 15 parts TWEEN 20, and 25 parts isosorbide dimethyl ether; the base collagen solution consists of type XVII collagen, type VII collagen, and type IV collagen in a weight ratio of 1:2:3. Preparation of a high-efficiency anti-aging composition: TWEEN 20 and base collagen solution were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a high-efficiency anti-aging composition.

[0052] Preparation of anti-aging essence: Add half water, butylene glycol, TR-2, 1,2-hexanediol and p-hydroxyacetophenone in sequence according to the ratio, heat to 80°C and stir to disperse evenly, then add arginine and the other half water solution, cool to 40°C, add the high-efficiency anti-aging composition and stir evenly to obtain anti-aging essence.

[0053] Comparative Example 8 An anti-aging serum is made from the following ingredients in the indicated weight percentages: 1,3-butanediol 5%, TR-2 0.2%, arginine 0.2%, 1,2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, a highly effective anti-aging composition 10%, and the balance being water. The highly effective anti-aging composition is made from the following ingredients in the indicated weight percentages: oil-based concentrated active ingredient 15 parts, ectoine 15 parts, TWEEN 20 15 parts, and isosorbide dimethyl ether 25 parts; Preparation of a high-efficiency anti-aging composition: TWEEN 20 and ectoine were mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether was added and stirred evenly, oil-based concentrated active ingredients were added, and the mixture was stirred at high speed for 5 minutes and then cooled to room temperature to obtain a high-efficiency anti-aging composition.

[0054] Preparation of anti-aging essence: Add half water, butylene glycol, TR-2, 1,2-hexanediol and p-hydroxyacetophenone in sequence according to the ratio, heat to 80°C and stir to disperse evenly, then add arginine and the other half water solution, cool to 40°C, add the high-efficiency anti-aging composition and stir evenly to obtain anti-aging essence.

[0055] Comparative Example 9 An anti-aging serum is made from the following ingredients in the indicated weight percentages: 1,3-butanediol 5%, TR-2 0.2%, arginine 0.2%, 1,2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, with the balance being water. It also includes a 10% high-efficiency anti-aging composition, which is made from the following ingredients in the indicated weight percentages: 30 parts base collagen solution, 15 parts ectoine, 15 parts TWEEN 20, and 25 parts isosorbide dimethyl ether. The base collagen solution is composed of type XVII, type VII, and type IV collagen in a weight ratio of 1:2:3. Preparation of high-efficiency anti-aging composition: TWEEN 20, base collagen solution and ectoine are mixed in proportion, stirred and dissolved at 45°C, isosorbide dimethyl ether is added and stirred evenly at high speed for 5 minutes, and then cooled to room temperature to obtain high-efficiency anti-aging composition.

[0056] Preparation of anti-aging essence: Add half water, butylene glycol, TR-2, 1,2-hexanediol and p-hydroxyacetophenone in sequence according to the ratio, heat to 80°C and stir to disperse evenly, then add arginine and the other half water solution, cool to 40°C, add the high-efficiency anti-aging composition and stir evenly to obtain anti-aging essence.

[0057] The performance tests of the anti-aging serums prepared in the examples and comparative examples were conducted using the following methods: Number of testers: 57, divided into 19 groups of 3 people each. There was no significant difference in skin condition among the groups. The age ranged from 45 to 55 years. Before the test, the subjects washed their faces and waited in a constant temperature and humidity environment (temperature 21-23℃, humidity 55-65%) for 30 minutes before the test. a. Anti-wrinkle and anti-aging effect test: The wrinkle reduction effect was tested using the human skin rapid optical imaging system (PRIMOS, Germany). Each group of subjects applied the products of Examples 11-20 and Comparative Examples 1-9 to their faces, using them once a day for 14 consecutive days. Facial wrinkle tests were conducted before use, after 3 days of use, and after washing their faces on the 14th day of use. b. Skin elasticity: A Cutometer MPA580 (Courage+Khazaka, Germany) was used to measure skin elasticity. The testing period was before use and 14 days later. The test site was the cheekbone area. The probe was used to measure the same area three times, and the average value was taken. The test parameter was R² (the ratio of skin rebound Ua without negative pressure to the maximum stretch Uf with negative pressure). The closer R² is to 1, the better the skin elasticity. The average change in R² = R² value after 14 days - R² value after 0 days; the average rate of change in R² = average change in R² / R² value after 0 days. Specific skin elasticity test results are shown in Table 1.

[0058] Table 1 Performance Test Results

[0059] As shown in Table 1, compared with Examples 11-14 and Comparative Examples 7-9, the essence prepared in Example 11 has better anti-wrinkle repair effects and skin elasticity changes than Examples 12-14 and Comparative Examples 7-9. It is believed that the concentrated active ingredients of the oil base create a stable environment for the base collagen solution to repair the DEJ layer and dermal collagen by immediately soothing dynamic wrinkles and reducing antioxidant damage; it helps the base collagen solution rebuild the epidermal-dermal connection and support structure, and enhances the structural basis for the action of the oil base ingredients; ectoine inhibits the degradation of both by inflammatory factors, prolongs its effect, and achieves the long-term benefits of reducing static wrinkles, improving firmness and sagging by enhancing the structural support of the DEJ layer and dermis. The anti-wrinkle effect of the component ratio in Example 11 is optimized.

[0060] Comparing Examples 11, 15-16, and 1-6, it is evident that the anti-wrinkle repair effect and skin elasticity changes of the essence prepared in Example 11 are superior to those of Examples 15-16 and 1-6. Analysis suggests that the XVII, VII, and IV collagens contained in the base collagen solution, at the mass ratio disclosed in this application, interact to strengthen the basic support of the epidermis, DEJ layer, and dermis, preventing insufficient support of the basal layer from causing epidermal sagging, thereby improving deep static wrinkles caused by facial contour drooping due to insufficient epidermal elasticity; effectively strengthening and achieving structural integrity and mechanical stability of the epidermis, DEJ layer, and dermis.

[0061] Comparing Examples 11 and 17-20, it can be seen that the anti-wrinkle repair effect and skin elasticity change of the essence prepared in Example 17 are better than those of Examples 11 and 18-20. It is believed that the fat-soluble properties of Inca Inchi oil encapsulate the chicory root extract to penetrate the dermis, strengthen the dermal support, improve firmness and elasticity, repair the epidermal lipid barrier, reduce moisture loss and improve dullness, enhance epidermal radiance, and improve the bioavailability of concentrated active ingredients in oil. Inca Inchi oil and chicory root extract, when used together in a specific ratio, show a synergistic effect as anti-wrinkle components.

[0062] The above are all preferred embodiments of this application and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made to the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A highly effective anti-aging composition, characterized in that: It is made from the following raw materials in parts by weight: 12-15 parts of oil-based concentrated active ingredients, 25-35 parts of base collagen solution, 15-18 parts of ectoine, 12-16 parts of TWEEN 20, and 22-25 parts of isosorbide dimethyl ether. The oil-based concentrated active ingredients include safflower seed oil, extracts of golden button flower / leaf / stem, extract of Astragalus membranaceus root, ubiquinone, and vitamin E. The base collagen solution includes type XVII collagen, type VII collagen, and type IV collagen.

2. The high-efficiency anti-aging composition according to claim 1, characterized in that: The highly effective anti-aging composition further includes 5-8 parts of anti-aging components, which include one or more of the following: acetyl hexapeptide-8, acetyl hexapeptide-1, ascorbic acid tetraisopalmitate, boswellia, vitamin C ethyl ether, alfalfa extract, cornflower extract, chrysanthemum extract, chicory root extract, and sacha inchi oil.

3. The high-efficiency anti-aging composition according to claim 1, characterized in that: The mass ratio of the oil-based concentrated active ingredient, the base collagen solution, and ectoine is 1:(1.5-2):(0.8-1.5).

4. The high-efficiency anti-aging composition according to claim 1, characterized in that: The mass ratio of type XVII collagen, type VII collagen, and type IV collagen is 1:(1.5-2):(2.4-3.2).

5. The high-efficiency anti-aging composition according to claim 2, characterized in that: The anti-aging components are chicory root extract and Inca Inchi oil in a mass ratio of 1:(4-6).

6. A skincare product, characterized in that: The product comprises the highly effective anti-aging composition according to any one of claims 1-5; the skin care product is one of an anti-aging serum and a skin care cream.

7. The skincare product according to claim 6, characterized in that: The skincare product is an anti-aging serum, and the mass percentage content of the highly effective anti-aging composition in the anti-aging serum is 2-10%.

8. The skincare product according to claim 7, characterized in that, The anti-aging essence is also made from the following ingredients by weight percentage: 1,3-butanediol 3-10%, TR-2 0.1-0.3%, arginine 0.1-0.3%, 1,2-hexanediol 0.5-0.8%, p-hydroxyacetophenone 0.3-0.6%, with the balance being water.

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