Traditional Chinese medicine preparation for hemorrhoid treatment medicine and preparation method of traditional Chinese medicine preparation

Abstract

The invention discloses a traditional Chinese medicine preparation for treating haemorrhoids and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation comprises costus root, eucommia ulmoides, rock candy and white spirit. The invention also provides a preparation method of the traditional Chinese medicine preparation for treating haemorrhoids, the traditional Chinese medicine preparation disclosed by the invention selects three to five traditional Chinese medicines for synergistic effect, has obvious curative effect on patients suffering from internal hemorrhoids, external hemorrhoids, internal and external mixed hemorrhoids and rectocele as well as unhealed patients, has the effect of treating both symptoms and root causes, is not easy to relapse after being healed, and has no toxic or side effect. Normal work and life are not affected when the preparation is taken, and the preparation is suitable for popularization and application.

Description

Technical Field

[0001] This invention relates to a traditional Chinese medicine preparation for the treatment of hemorrhoids and its preparation method. Background Technology

[0002] Hemorrhoids, also known as piles, are one of the most common anal diseases in clinical practice. The modern concept of hemorrhoids was proposed by the British scientist Thomson in 1975: hemorrhoids are pathological enlargement of the anal cushions in the lower rectum. Depending on their location, hemorrhoids can be classified as internal hemorrhoids, external hemorrhoids, and mixed hemorrhoids. Internal hemorrhoids are considered to be pathological changes or displacements of the supporting structures, vascular plexuses, and arteriovenous anastomoses of the anal cushions (anal canal vascular cushions). External hemorrhoids are pathological dilation or thrombosis of the subcutaneous vascular plexus distal to the dentate line. Mixed hemorrhoids are a combination of internal and external hemorrhoids.

[0003] Traditional Chinese medicine believes that hemorrhoids are caused by external pathogenic factors, excessive hunger or overeating, or irregular eating habits, leading to deficiency and stagnation of qi and blood. Western medicine has no unified standard, with theories of anal cushion displacement and varicose veins. Mongolian medicine believes that hemorrhoids are caused by imbalance of the three elements of Hei, Xila, and Badagan. Literature: Li Xiaomin. Analysis of the efficacy of integrated traditional Chinese and Western medicine in the treatment of 130 patients with hemorrhoids [J]. Clinical Medical Engineering, 2010, 17(7):2. It is mentioned that the current Western medicine treatment mainly includes rubber band ligation, injection therapy and surgery, while the traditional Chinese medicine treatment includes the use of Chinese herbal decoctions and Chinese herbal fumigation. Literature: Xilin Tuya, Yu Lijun, Fu Haiqi, et al. Research progress in clinical treatment of hemorrhoids [J]. Journal of Baotou Medical College, 2022, 38(5):4. It also mentions external application, sitz bath, anal plugging, acupuncture and padding. Among them, the treatment of Chinese herbal decoctions has the advantages of strong targeting, painlessness and high safety, and is widely accepted by patients.

[0004] In the prior art, CN115887601A discloses a composition for hemorrhoids and its preparation method, relating to the field of traditional Chinese medicine technology. This composition for hemorrhoids includes: Citrus aurantium, rhubarb, Astragalus membranaceus, Gallnut, Nelumbo nucifera receptacle, Forsythia suspensa, Siraitia grosvenorii, Angelica sinensis, Curcuma zedoaria, Ligusticum chuanxiong, Taraxacum mongolicum, Phellodendron chinense, Lithospermum erythrorhizon, and borneol. This composition for hemorrhoids has a good therapeutic effect on hemorrhoids, showing significant efficacy against internal hemorrhoids, external hemorrhoids, and mixed hemorrhoids. However, this product is for external use only and does not provide a comprehensive cure.

[0005] CN1970006A discloses a traditional Chinese medicine wine for treating hemorrhoids, which is made by soaking 31 traditional Chinese medicines such as astragalus membranaceus, red ginseng, cistanche deserticola, angelica sinensis, eucommia ulmoides, acanthopanax giraldii harms, human placenta, frankincense, scorpio, scolopendra, and pig's trotter in white liquor. It is convenient to take orally, does not affect normal work and life, and has a significant treatment effect. Although the usage method of this product is oral administration, the traditional Chinese medicine components are as many as 31 kinds, not only with high cost, but also the preparation method is relatively cumbersome. Summary of the Invention

[0006] One of the objectives of the present invention is to provide a traditional Chinese medicine preparation for treating hemorrhoids, which has significant effects on internal hemorrhoids, external hemorrhoids, and mixed hemorrhoids, etc., has a rapid onset, and is not easy to relapse. Another objective of the present invention is to provide a preparation method for the traditional Chinese medicine preparation for treating hemorrhoids.

[0007] These and other objectives of the present invention will be further elaborated through the following detailed description and explanation.

[0008] On the one hand, the present invention provides a traditional Chinese medicine preparation for treating hemorrhoids, and the traditional Chinese medicine preparation includes: Guan Jin, eucommia ulmoides, rock sugar, and white liquor.

[0009] In a specific embodiment of the present invention, the traditional Chinese medicine preparation, calculated by weight份数, includes: 90-110 parts of Guan Jin, 1-3 parts of eucommia ulmoides, 80-110 parts of rock sugar, and 2000-2600 parts of white liquor.

[0010] Specifically, Guan Jin can be 90 parts, 100 parts, or 110 parts, eucommia ulmoides can be 1 part, 2 parts, or 3 parts, rock sugar can be 80 parts, 90 parts, 100 parts, or 110 parts, and white liquor can be 2000 parts, 2100 parts, 2200 parts, 2300 parts, 2400 parts, 2500 parts, or 2600 parts.

[0011] In a specific embodiment, the traditional Chinese medicine preparation, calculated by weight份数, includes: 100 parts of Guan Jin, 2.5 parts of eucommia ulmoides, 100 parts of rock sugar, and 2500 parts of white liquor.

[0012] In a specific embodiment of the present invention, the traditional Chinese medicine preparation further includes dandelion.

[0013] Preferably, the traditional Chinese medicine preparation, calculated by weight份数, includes: 1-3 parts of dandelion. Specifically, dandelion can be 1 part, 1.5 parts, 2 parts, 2.5 parts, or 3 parts.

[0014] More preferably, the traditional Chinese medicine preparation, calculated by weight份数, includes: 2.5 parts of dandelion.

[0015] In another specific embodiment of the present invention, it further includes: 1-3 parts dried figs, specifically, dandelion can be 1 part, 1.5 parts, 2 parts, 2.5 parts or 3 parts.

[0016] More preferably, the traditional Chinese medicine preparation comprises, by weight, 2.5 parts dried figs.

[0017] In one specific embodiment of the present invention, the alcohol content of the liquor is 60-65 degrees. Specifically, the alcohol content of the liquor can be 60 degrees, 61 degrees, 62 degrees, 63 degrees, 64 degrees, or 65 degrees.

[0018] In another aspect, the present invention also provides a method for preparing a traditional Chinese medicine preparation for treating hemorrhoids, comprising the following steps: Step 1: Accurately weigh each type of Chinese medicine; Step 2, Cleaning: Rinse the Chinese herbs from Step 1 in clean water to remove surface impurities and deposits; Step 3: After drying the Chinese herbs washed in Step 2, crush them, sieve them, and mix them. Step 4: Place the crushed Chinese medicine from Step 3 into a sealed glass container filled with white wine and soak for 6-12 months in a dark, room temperature environment. Step 5: Filtering; Step 6, Packaging: Pack the product in glass bottles with sealed caps.

[0019] Compared with the prior art, the beneficial effects of the present invention are as follows: In this invention, a traditional Chinese medicine preparation for treating hemorrhoids uses *Geranium wilfordii*, also known as *Lao Niu Jin* or *Lao Guan Jin*, which has the effects of dispelling wind, promoting blood circulation, clearing heat and detoxifying, relaxing muscles and tendons, and unblocking meridians. As the principal ingredient, *Eucommia ulmoides* tonifies the liver and kidneys and strengthens tendons and bones. Rock sugar is sweet and neutral in nature, enters the spleen and lung meridians, and contains trace amounts of protein and essential amino acids, with effects of moistening the lungs and generating fluids, soothing liver qi, clearing heat and drying dampness. These are used as adjuvant ingredients. Furthermore, in this invention, dandelion and dried figs have an interactive relationship; when used in a specific ratio, they promote the therapeutic effect of the prescription. This invention's traditional Chinese medicine preparation uses three to five herbs working synergistically, showing significant efficacy for patients with internal hemorrhoids, external hemorrhoids, mixed internal and external hemorrhoids, rectal prolapse, and those with chronic hemorrhoids, achieving both symptomatic and root-cause treatment. Recurrence is less likely after recovery, and normal work and life are not affected during the use of this traditional Chinese medicine preparation. The traditional Chinese medicine preparation of this invention uses three to five kinds of traditional Chinese medicine, has few components, no toxic side effects, low cost, fast onset of action, and simple preparation method, which is conducive to its promotion and application. Attached Figure Description

[0020] The specific embodiments of the present invention will be described in further detail below with reference to the accompanying drawings.

[0021] Figure 1 A flowchart illustrating the preparation method of a traditional Chinese medicine preparation for the treatment of hemorrhoids is shown. Detailed Implementation

[0022] The present invention will be further described below with reference to specific embodiments. These embodiments should be understood as illustrative only and not as limiting the scope of protection of the present invention. Those skilled in the art will recognize that different variations or modifications can be made to the present invention based on the above description, and these equivalent variations and modifications also fall within the scope defined by the claims of the present invention.

[0023] Example 1

[0024] A traditional Chinese medicine preparation for treating hemorrhoids includes: 2500 grams of baijiu (Chinese white liquor), 110 grams of Guanjin (a traditional Chinese medicine), 1.5 grams of Eucommia ulmoides, 1.5 grams of dandelion, 1.5 grams of fig, and 100 grams of rock sugar. The baijiu has an alcohol content of 60 degrees.

[0025] Reference Figure 1 A method for preparing a traditional Chinese medicine preparation for the treatment of hemorrhoids is carried out according to the following scheme: Step 1: Accurately weigh each type of Chinese medicine; Step 2, Cleaning: Rinse the Chinese herbs from Step 1 in clean water to remove surface impurities and deposits; Step 3: After drying the Chinese herbs washed in Step 2, crush them, sieve them, and mix them. Step 4: Place the crushed Chinese medicine from Step 3 into a sealed glass container filled with white wine and soak for 6 months in a dark, room temperature environment. Step 5: Filtering; Step 6, Packaging: Pack the product in glass bottles with sealed caps.

[0026] Example 2

[0027] A traditional Chinese medicine preparation for treating hemorrhoids includes: 2000 grams of baijiu (Chinese white liquor), 100 grams of Guanjin (a traditional Chinese medicine), 3 grams of Du Zhong (Eucommia ulmoides), 3 grams of dandelion, and 80 grams of rock sugar, wherein the baijiu has an alcohol content of 61 degrees.

[0028] Reference Figure 1 A method for preparing a traditional Chinese medicine preparation for the treatment of hemorrhoids is carried out according to the following scheme: Step 1: Accurately weigh each type of Chinese medicine; Step 2, Cleaning: Rinse the Chinese herbs from Step 1 in clean water to remove surface impurities and deposits; Step 3: After drying the Chinese herbs washed in Step 2, crush them, sieve them, and mix them. Step 4: Place the crushed Chinese medicine from Step 3 into a sealed glass container filled with white wine and soak for 7 months in a dark, room temperature environment. Step 5: Filtering; Step 6, Packaging: Pack the product in glass bottles with sealed caps.

[0029] Example 3

[0030] A traditional Chinese medicine preparation for treating hemorrhoids includes: 2200 grams of baijiu (Chinese white liquor), 100 grams of Guanjin (a traditional Chinese medicine), 1.5 grams of Du Zhong (Eucommia ulmoides), 1.5 grams of dandelion, 1.5 grams of fig, and 90 grams of rock sugar, wherein the baijiu has an alcohol content of 62 degrees.

[0031] Reference Figure 1 A method for preparing a traditional Chinese medicine preparation for the treatment of hemorrhoids is carried out according to the following scheme: Step 1: Accurately weigh each type of Chinese medicine; Step 2, Cleaning: Rinse the Chinese herbs from Step 1 in clean water to remove surface impurities and deposits; Step 3: After drying the Chinese herbs washed in Step 2, crush them, sieve them, and mix them. Step 4: Place the crushed Chinese medicine from Step 3 into a sealed glass container filled with white wine and soak for 8 months in a dark, room temperature environment. Step 5: Filtering; Step 6, Packaging: Pack the product in glass bottles with sealed caps.

[0032] Example 4

[0033] A traditional Chinese medicine preparation for treating hemorrhoids includes: 2200 grams of baijiu (Chinese white liquor), 100 grams of Guanjin (a traditional Chinese medicine), 1.5 grams of Du Zhong (Eucommia ulmoides), 1.5 grams of dandelion, and 90 grams of rock sugar, wherein the baijiu has an alcohol content of 63 degrees.

[0034] Reference Figure 1 A method for preparing a traditional Chinese medicine preparation for the treatment of hemorrhoids is carried out according to the following scheme: Step 1: Accurately weigh each type of Chinese medicine; Step 2, Cleaning: Rinse the Chinese herbs from Step 1 in clean water to remove surface impurities and deposits; Step 3: After drying the Chinese herbs washed in Step 2, crush them, sieve them, and mix them. Step 4: Place the crushed Chinese medicine from Step 3 into a sealed glass container filled with white wine and soak for 9 months in a dark, room temperature environment. Step 5: Filtering; Step 6, Packaging: Pack the product in glass bottles with sealed caps.

[0035] Example 5

[0036] A traditional Chinese medicine preparation for treating hemorrhoids includes: 2000 grams of baijiu (Chinese white liquor), 100 grams of Guanjin (a traditional Chinese medicine), 3 grams of Du Zhong (Eucommia ulmoides), 3 grams of fig, and 80 grams of rock sugar, wherein the baijiu has an alcohol content of 64 degrees.

[0037] Reference Figure 1 A method for preparing a traditional Chinese medicine preparation for the treatment of hemorrhoids is carried out according to the following scheme: Step 1: Accurately weigh each type of Chinese medicine; Step 2, Cleaning: Rinse the Chinese herbs from Step 1 in clean water to remove surface impurities and deposits; Step 3: After drying the Chinese herbs washed in Step 2, crush them, sieve them, and mix them. Step 4: Place the crushed Chinese medicine from Step 3 into a sealed glass container filled with white wine and soak for 10 months in a dark, room temperature environment. Step 5: Filtering; Step 6, Packaging: Pack the product in glass bottles with sealed caps.

[0038] Example 6

[0039] A traditional Chinese medicine preparation for treating hemorrhoids includes: 2500g of baijiu (Chinese white liquor), 100g of Guanjin (a traditional Chinese medicine), 2.5g of Du Zhong (Eucommia ulmoides), 2.5g of dandelion, 2.5g of fig, and 100g of rock sugar, wherein the baijiu has an alcohol content of 65%.

[0040] Reference Figure 1 A method for preparing a traditional Chinese medicine preparation for the treatment of hemorrhoids is carried out according to the following scheme: Step 1: Accurately weigh each type of Chinese medicine; Step 2, Cleaning: Rinse the Chinese herbs from Step 1 in clean water to remove surface impurities and deposits; Step 3: After drying the Chinese herbs washed in Step 2, crush them, sieve them, and mix them. Step 4: Place the pulverized Chinese medicine from Step 3 into a sealed glass container filled with white wine and soak for 12 months in a dark, room-temperature environment. Step 5: Filtering; Step 6, Packaging: Pack the product in glass bottles with sealed caps.

[0041] Example 7: Clinical observation of the drug of the present invention for treating hemorrhoids 1. General Information A total of 35 patients were included, of whom 27 were male and 8 were female, with a male-to-female ratio of 3:1. The ages of the patients were as follows: 3 were 20-30 years old, 8 were 31-40 years old, 10 were 41-50 years old, and 14 were over 50 years old. Among them, 21 were government officials, senior executives and technical personnel, 9 were ordinary staff members, 2 were teachers, and 3 were drivers.

[0042] 2. Diagnostic criteria Symptoms include anal swelling, pain, recurrent bleeding during bowel movements (sometimes profuse bleeding), prolapse of the anal canal and rectal mucosa, fatigue, lower back pain, insomnia, and excessive dreaming. Hemorrhoids are classified into internal hemorrhoids, external hemorrhoids, and mixed hemorrhoids. Clinical diagnosis is mainly based on the patient's clinical symptoms and digital rectal examination, without the need for special examinations.

[0043] Internal hemorrhoids are classified into four stages: Stage I internal hemorrhoids present with dripping or spurting bleeding during bowel movements. Stage II internal hemorrhoids present with bright red blood during bowel movements, and the hemorrhoids prolapse but can spontaneously reduce. Stage III internal hemorrhoids present with bright red blood during bowel movements, and the prolapsed hemorrhoids require manual reduction. Stage IV internal hemorrhoids present with small amounts of bright red blood during bowel movements, and cannot be manually reduced.

[0044] External hemorrhoids include four types: varicose external hemorrhoids, connective tissue external hemorrhoids, inflammatory external hemorrhoids, and thrombosed external hemorrhoids.

[0045] Varicose external hemorrhoids: These are soft, round or oval lumps formed at the anal margin due to congestion and varicose veins in the external hemorrhoidal plexus below the dentate line. Various factors that cause hemorrhoids can lead to varicose external hemorrhoids, including prolonged sitting or standing, chronic constipation, chronic diarrhea, sustained increases in abdominal pressure, and infection.

[0046] Connective tissue external hemorrhoids: These are caused by repeated episodes of chronic inflammation, leading to fibrosis and connective tissue hyperplasia of the skin around the anus, forming skin tags. They are primarily composed of hyperplastic fibrous connective tissue, with dilated blood vessels being rare. They can be single or multiple. They can also be a result of thrombosed external hemorrhoids or surgical remnants of anal surgery; infection can cause pain.

[0047] Inflammatory external hemorrhoids: caused by infection after anal injury, or by inflammation and edema of perianal skin tags caused by anal fissures.

[0048] Thrombosed external hemorrhoids: This is a common type of external hemorrhoid, often caused by excessive straining during bowel movements, strenuous activity, or violent coughing, leading to rupture of veins at the anal margin. Blood seeps into the connective tissue, forming a thrombus that creates a round or oval subcutaneous mass around the anus, accompanied by severe pain. Initially, it is soft, but hardens after a few days. If it becomes repeatedly infected, it can lead to connective tissue hyperplasia, forming connective tissue external hemorrhoids; if the infection worsens, it can form a perianal abscess.

[0049] Mixed hemorrhoids can present with symptoms of both internal and external hemorrhoids, including rectal bleeding and prolapse.

[0050] 3. Treatment methods The traditional Chinese medicine preparation uses the formula from Example 6. Take 50mL-100mL once a night, approximately 15 minutes before bedtime. For patients with more severe symptoms, such as rectal bleeding or incarceration, take an additional 50mL once a day in the morning. One course of treatment is 3 days, and two courses are recommended.

[0051] 4. Efficacy evaluation criteria Significant effect: No recurrence was observed after 3 months of observation following the cure of hemorrhoids.

[0052] Improvement: The diameter of the lump or hemorrhoids shrinks, the symptoms of rectal prolapse are reduced or disappear, the symptoms of incarceration are reduced or disappear, the symptoms of anal swelling and pain are reduced or disappear, and the symptoms of long-term and repeated bleeding during defecation are reduced or disappear. After treatment, the patient has three or more of the above conditions.

[0053] Ineffective: Those who do not meet the criteria for improvement.

[0054] Effective: Both those showing significant improvement and those showing improvement are considered effective.

[0055] Table 1. Observation of therapeutic effects after treatment

[0056] As shown in Table 1, during the two courses of treatment (6 days), 35 cases were treated with the drug of this invention. The results showed that 15 cases were significantly effective, 20 cases were improved, and 0 cases were ineffective. The effective rate was 42.86%, the improvement rate was 57.14%, and the total effective rate was 100%.

[0057] It should be understood that the specific embodiments described above are merely illustrative or explanatory of the principles of the invention and do not constitute a limitation thereof. Therefore, any modifications, equivalent substitutions, improvements, etc., made without departing from the spirit and scope of the invention should be included within the protection scope of the invention. Furthermore, the appended claims are intended to cover all variations and modifications falling within the scope and boundaries of the appended claims, or equivalent forms of such scope and boundaries.

Claims

1. A traditional Chinese medicine preparation for the treatment of hemorrhoids, characterized in that, The traditional Chinese medicine preparation includes: Guan Jin, Eucommia ulmoides, rock sugar and white liquor.

2. The traditional Chinese medicine preparation according to claim 1, characterized in that, The traditional Chinese medicine preparation, calculated by weight parts, includes: 90-110 parts of Guan Jin, 1-3 parts of Eucommia ulmoides, 80-110 parts of rock sugar and 2000-2600 parts of white liquor.

3. The traditional Chinese medicine preparation according to claim 1, characterized in that, The traditional Chinese medicine preparation, calculated by weight parts, includes: 100 parts of Guan Jin, 2.5 parts of Eucommia ulmoides, 100 parts of rock sugar and 2500 parts of white liquor.

4. The traditional Chinese medicine preparation according to any one of claims 1-3, characterized in that, The traditional Chinese medicine preparation further includes dandelion.

5. The traditional Chinese medicine preparation according to claim 4, characterized in that, The traditional Chinese medicine preparation, calculated by weight parts, includes: 1-3 parts of dandelion.

6. A traditional Chinese medicine preparation for hemorrhoids according to claim 5, characterized in that, The traditional Chinese medicine preparation, calculated by weight parts, includes: 2.5 parts of dandelion.

7. The traditional Chinese medicine preparation according to claim 6, characterized in that, The traditional Chinese medicine preparation further includes: 1-3 parts of dried figs.

8. The traditional Chinese medicine preparation according to claim 7, characterized in that, The traditional Chinese medicine preparation, calculated by weight parts, includes 2.5 parts of dried figs.

9. The traditional Chinese medicine preparation according to claim 8, characterized in that, The alcohol degree of the white liquor is 60-65 degrees.

10. A method for preparing a traditional Chinese medicine preparation according to any one of claims 5 to 9, characterized in that, It includes the following steps: Step 1: Accurately weigh each traditional Chinese medicine. Step 2: Cleaning: Put the traditional Chinese medicines in Step 1 into clean water for cleaning to remove surface impurities and sediments. Step 3: After drying the cleaned traditional Chinese medicines in Step 2, crush them, sieve them and mix them. Step 4: Put the crushed traditional Chinese medicines in Step 3 into a glass sealed container filled with white liquor, and soak them for 6-12 months under the conditions of avoiding light and room temperature. Step 5: Filter. Step 6: Packaging: Package with a glass bottle with a sealed cap.

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