Traditional Chinese medicine tea drink bag for relieving chronic fatigue syndrome and preparation method of traditional Chinese medicine tea drink bag

Abstract

The invention discloses a traditional Chinese medicine tea drink bag for relieving chronic fatigue syndrome and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine, and the traditional Chinese medicine tea drink bag comprises the following raw medicinal materials in parts by mass: 20-40 parts of astragalus membranaceus, 5-20 parts of American ginseng and 20-40 parts of hairyvein agrimony. The invention further discloses a preparation method of the traditional Chinese medicine tea drink bag. The radix astragali tea bag has the advantages that the radix astragali tea bag is composed of radix astragali, American ginseng and hairyvein agrimony, a collaborative network of tonifying qi, nourishing yin and removing stagnation is formed, the independent tea bag design is adopted, the medicine effect can be released without decoction and hot water brewing, the tea bag is suitable for the fast-paced life of the modern society, and the tea bag can be flexibly applied to various scenes such as offices, homes and travels; the limitation that traditional Chinese medicine needs to be decocted for a long time is broken.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine technology, and more specifically, to a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome and its preparation method. Background Technology

[0002] Chronic fatigue syndrome (CFS) is a syndrome characterized by prolonged fatigue, a manifestation of multiple systemic diseases that arises under the fast-paced, stressful lifestyles of contemporary society. Its pathogenesis is highly complex, resulting from the combined effects of multiple factors, including genetics, environment, infection, immunity, and neurological dysfunction. Clinical manifestations primarily involve a decline and exhaustion in the functions of the nervous, musculoskeletal, digestive, urinary, and sensory systems. Its basic characteristics include prolonged and extreme lethargy that is not relieved by rest, and the absence of any related organic lesions in various examinations. The fast-paced, fatigue-prone, and stressful lifestyles of contemporary young people, coupled with their reliance on coffee and milk tea, often lead them to seek relief through massage and acupuncture, but these methods are time-consuming, have limited effectiveness, and foster a strong sense of dependency.

[0003] Currently, Western medicine treatment for CFS mainly focuses on symptomatic support. For example, drugs such as fludrocortisone, low-dose beta-blockers, alpha-adrenergic agonists, and piracetam are used to treat orthostatic intolerance; trazodone, lunitrazepam, and tricyclic antidepressants are used to treat insomnia; modafinil or dextroamphetamine are used to improve cognitive problems; gabapentin, pregabalin, low-dose naltrexone, and duloxetine are used to treat pain; rifaximin, vancomycin, and metronidazole are used to address gastrointestinal issues; and immunotherapy is used to improve symptoms such as joint pain. However, each drug has significant side effects, is prone to relapse, and there is no satisfactory comprehensive treatment plan.

[0004] While there is no specific disease name for chronic fatigue syndrome in traditional Chinese medicine, ancient texts contain numerous descriptions of fatigue as a symptom. The *Huangdi Neijing* (Yellow Emperor's Inner Classic) uses dozens of terms related to "fatigue," such as "paralysis," "drowsiness," "laziness," "slackness," "inactivity of the limbs," and "desire to lie down." The *Huangdi Neijing Suwen* (Yellow Emperor's Inner Classic Plain Questions) states, "Prolonged staring injures the blood, prolonged lying injures the qi, prolonged sitting injures the flesh, prolonged standing injures the bones, and prolonged walking injures the tendons; these are called the five types of fatigue." The *Yijia Siyao* (Essentials of Medicine) also points out, "Excessive mental activity strains the mind, excessive planning strains the liver, excessive thinking about unexpected events strains the spleen, worrying about events strains the lungs, and excessive sexual desire strains the kidneys." Viral infections are considered exogenous pathogenic factors, and all six pathogenic factors can lead to dysfunction of the five internal organs. As Wu Cheng of the Qing Dynasty stated in his *Buju Ji* (Collection of Unreserved Writings), deficiency is not only caused by internal injury but also commonly by external pathogenic factors. Furthermore, wind is not the primary pathogenic factor among the six external pathogenic factors; all six can cause fatigue. Its causes are both internal and external, and the location of the disease involves multiple organs and systems. The nature of the disease is both deficiency and excess, or a mixture of deficiency and excess. Therefore, its pathogenesis can be summarized as deficiency of the organs and depletion of their own functions, resulting in fatigue.

[0005] However, fatigue is a complex, multifactorial physical condition that is often underestimated by medical professionals. As fatigue progresses, it can lead to negative effects such as decreased work efficiency, reduced physical activity, social interaction and recreational abilities, as well as emotional distress and sadness, especially affecting young people today. Summary of the Invention

[0006] To address the shortcomings of existing technologies, this invention provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome and its preparation method. By integrating traditional Chinese medicine theory, modern technology, and user needs, it avoids the need for traditional decoctions to be boiled and the need for carefully selected physicians for acupuncture and massage. Furthermore, by replacing coffee and milk tea with tea, it can achieve long-term regulation of bodily functions through daily consumption, enhance anti-fatigue ability, and conform to the concept of "prevention of disease", thus reducing the risk of chronic fatigue syndrome.

[0007] To achieve the above objectives, the present invention adopts the following technical solution:

[0008] A traditional Chinese medicine tea bag for relieving chronic fatigue syndrome includes the following raw medicinal materials in parts by weight: 20-40 parts of Astragalus membranaceus, 5-20 parts of American ginseng, and 20-40 parts of Agrimonia pilosa.

[0009] Preferably, the herbal tea bag comprises the following raw medicinal materials in parts by weight: 24-36 parts of Astragalus membranaceus, 8-17 parts of American ginseng, and 24-36 parts of Agrimonia pilosa.

[0010] Preferably, the herbal tea bag comprises the following raw medicinal materials in parts by weight: 28-32 parts of Astragalus membranaceus, 10-15 parts of American ginseng, and 28-32 parts of Agrimonia pilosa.

[0011] Preferably, the herbal tea bag also includes pharmaceutically acceptable excipients.

[0012] Preferably, the herbal tea bag is brewed with boiling water.

[0013] The present invention also provides an application of the above-mentioned herbal tea bag for relieving chronic fatigue syndrome in the treatment of chronic fatigue syndrome.

[0014] The present invention also provides a method for preparing the above-mentioned Chinese herbal tea bag, comprising the following steps:

[0015] Step 1: Weigh the raw medicinal materials according to the weight ratio, clean, dry, cut, and mix evenly;

[0016] Step 2: Grind the raw medicinal materials processed in Step 1 into a fine powder and sieve it through a Chinese medicine sieve;

[0017] Step 3: Divide and package the fine powder from Step 2.

[0018] Preferably, the particle size of the fine powder is 100-200 mesh.

[0019] Preferably, the fine powder in step three is packaged in filter paper bags, which are one of the following: ordinary plastic non-woven fabric, corn fiber, plant fiber, food-grade nylon mesh, or PLA biodegradable environmentally friendly material.

[0020] The beneficial effects of adopting the technical solution of this invention are as follows:

[0021] The traditional Chinese medicine composition provided by this invention consists of Astragalus membranaceus, American ginseng, and Agrimonia pilosa. In traditional Chinese medicine theory, all three herbs have the effect of tonifying deficiency and strengthening the body, forming a synergistic network of "tonifying qi-nourishing yin-unblocking": Astragalus membranaceus tonifies qi to promote blood circulation, American ginseng nourishes yin to nourish tendons and vessels, and Agrimonia pilosa invigorates blood to unblock stagnation; it can significantly increase SOD activity (30-50% higher than that of single herbs), reduce blood urea nitrogen level, and prolong the time of exhaustive swimming by more than 45%, and its effect is better than that of single herbs.

[0022] This invention features an individual tea bag design, eliminating the need for decoction; simply steeping in hot water releases the medicinal effects, making it suitable for the fast-paced lifestyle of modern society. It can be flexibly applied in various scenarios such as the office, home, and travel, breaking the limitations of traditional Chinese medicine which requires long-term decoction. Furthermore, the tea bag has a slightly sweet taste and significant tonic effects, serving as a substitute for coffee and milk tea. It satisfies health needs while reducing reliance on sugar or caffeine. Through careful formulation, the various Chinese medicinal ingredients work synergistically to enhance anti-fatigue effects. Attached Figure Description

[0023] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0024] Figure 1 This is a comparison chart of the semi-quantitative scale scores of rats in each group during the experiment of this invention. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, not all of them. Therefore, the detailed description of the embodiments provided by the present invention below is not intended to limit the scope of the claimed invention, but merely to represent selected embodiments of the invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of the present invention.

[0026] This implementation method is based on the inventor's more than 30 years of clinical experience in treating patients with chronic fatigue syndrome. It can effectively relieve muscle soreness and fatigue, improve patients' exercise tolerance, and significantly improve symptoms such as memory decline and cognitive impairment, receiving widespread praise from patients. The specific implementation method is as follows:

[0027] A traditional Chinese medicine tea bag for relieving chronic fatigue syndrome includes the following raw medicinal materials: Astragalus membranaceus, American ginseng, and Agrimonia pilosa.

[0028] Astragalus membranaceus (Huangqi) enters the spleen and lung meridians, tonifies the middle energizer and replenishes qi, raises yang and lifts prolapse, making it a "key medicine for tonifying qi." Modern research has found that astragalus polysaccharides in astragalus can activate the AMPK pathway, promote glucose uptake and mitochondrial function, and improve ATP production efficiency, thereby improving energy metabolism. American ginseng (Xiangshen) is cool in nature and moistening in texture, tonifies qi and nourishes yin, clears heat and generates fluids. Modern research has found that its main component, ginsenoside Rg1, can inhibit excessive corticosterone secretion, alleviate hypothalamic-pituitary-adrenal axis dysfunction caused by chronic stress; it also promotes mTOR pathway activity in muscle cells, increases myosin heavy chain expression, and delays muscle fatigue; and by inhibiting the NF-κB pathway, it reduces hippocampal neuronal apoptosis and improves cognitive fatigue. Agrimony, with its bitter and astringent taste, enters the heart and liver meridians. It possesses astringent, hemostatic, antimalarial, antidiarrheal, detoxifying, and tonifying effects, and can be used to treat hemoptysis, hematemesis, and fatigue. Agrimony is also known as "the grass of exhaustion." The famous traditional Chinese medicine practitioner, Gan Zuwang, created the "Three Immortals Decoction," in which Agrimony is the main ingredient. He stated, "The grass of exhaustion is Agrimony… It can be used for various diseases without external pathogens, especially for those suffering from fatigue and lethargy… with excellent results. Therefore, I often jokingly call it 'the hormone of traditional Chinese medicine.'" Agrimony extract can activate lactate dehydrogenase activity, accelerating the conversion of lactate to pyruvate in skeletal muscle and relieving muscle fatigue.

[0029] In one preferred embodiment, the herbal tea bag comprises the following raw medicinal materials in parts by weight: 20-40 parts of Astragalus membranaceus, 5-20 parts of American ginseng, and 20-40 parts of Agrimonia pilosa.

[0030] In one preferred embodiment, the herbal tea bag comprises the following raw medicinal materials in parts by weight: 24-36 parts of Astragalus membranaceus, 8-17 parts of American ginseng, and 24-36 parts of Agrimonia pilosa.

[0031] In one preferred embodiment, the herbal tea bag comprises the following raw medicinal materials in parts by weight: 28-32 parts of Astragalus membranaceus, 10-15 parts of American ginseng, and 28-32 parts of Agrimonia pilosa.

[0032] In a preferred embodiment, the herbal tea bag also includes pharmaceutically acceptable excipients.

[0033] In one preferred embodiment, the herbal tea bag is brewed with boiling water.

[0034] The present invention also provides an application of the above-mentioned herbal tea bag for relieving chronic fatigue syndrome in the treatment of chronic fatigue syndrome.

[0035] The present invention also provides a method for preparing the above-mentioned Chinese herbal tea bag, comprising the following steps:

[0036] Step 1: Weigh the raw medicinal materials according to the weight ratio, clean, dry, cut, and mix evenly;

[0037] Step 2: Grind the raw medicinal materials processed in Step 1 into a fine powder and sieve it through a Chinese medicine sieve;

[0038] Step 3: Divide and package the fine powder from Step 2.

[0039] In a preferred embodiment, the particle size of the fine powder is 100-200 mesh.

[0040] In a preferred embodiment, the fine powder in step three is packaged in filter paper bags, which are one of the following: ordinary plastic non-woven fabric, corn fiber, plant fiber, food-grade nylon mesh, or PLA biodegradable environmentally friendly material.

[0041] The present invention will be further described in detail below with reference to specific embodiments:

[0042] Example 1

[0043] This embodiment 1 provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome, using the following proportions of raw materials: Astragalus membranaceus 20 parts, American ginseng 5 parts, and Agrimonia pilosa 20 parts. The preparation method of this embodiment 1 is as follows:

[0044] Step 1: Weigh the raw materials according to the weight ratio, clean, dry, cut, and mix evenly;

[0045] Step 2: Place the raw materials from Step 1 into a grinder and grind them into fine powder with a particle size of 100-200 mesh, and then sieve them through a traditional Chinese medicine sieve.

[0046] Step 3: Divide the fine powder from Step 2 into filter paper bags made of plant fiber and seal them to obtain the final product.

[0047] Example 2

[0048] Example 2 provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome. The raw materials are prepared according to the following proportions by weight: Astragalus membranaceus 24 parts, American ginseng 8 parts, and Agrimonia pilosa 24 parts. The preparation method for Example 2 is the same as in Example 1.

[0049] Example 3

[0050] This embodiment 3 provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome, using the following proportions of raw materials: Astragalus membranaceus 28 parts, American ginseng 10 parts, and Agrimonia pilosa 28 parts. The preparation method of this embodiment 3 is the same as that of embodiment 1.

[0051] Example 4

[0052] Example 4 provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome, using the following proportions of raw materials: Astragalus membranaceus 30 parts, American ginseng 12 parts, and Agrimonia pilosa 30 parts. The preparation method for Example 4 is the same as that for Example 1.

[0053] Example 5

[0054] Example 5 provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome, using the following proportions of raw materials: Astragalus membranaceus 32 parts, American ginseng 15 parts, and Agrimonia pilosa 32 parts. The preparation method of Example 5 is the same as that of Example 1.

[0055] Example 6

[0056] Example 6 provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome, using the following proportions of raw materials: Astragalus membranaceus 36 parts, American ginseng 17 parts, and Agrimonia pilosa 36 parts. The preparation method for Example 6 is the same as that for Example 1.

[0057] Example 7

[0058] Example 7 provides a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome, using the following proportions of raw materials: Astragalus membranaceus 40 parts, American ginseng 20 parts, and Agrimonia pilosa 40 parts. The preparation method for Example 7 is the same as that for Example 1.

[0059] To further observe the effectiveness of the herbal tea bag of this application, animal experiments were conducted to observe the therapeutic effect of the herbal tea bag of this application on rats with chronic fatigue syndrome.

[0060] 1. Materials and Methods

[0061] 1.1 Experimental subjects and grouping

[0062] Forty-five SPF-grade male SD rats, weighing (210±10) g, were acclimatized for one week with unrestricted diet and a 12-hour light-dark cycle. The ambient temperature was (22±1)℃ and the humidity was (45±5)%. Adaptive swimming training began on day 4 of acclimatization, and general condition assessment, weighing, and behavioral tests were performed on day 7. Rats were then randomly divided into a blank control group, a model control group, and a treatment group, with 15 rats in each group. This experiment was approved by the Animal Ethics Committee of Henan University of Traditional Chinese Medicine, and all procedures strictly adhered to the "Regulations on the Management of Experimental Animals."

[0063] 1.2 Main Equipment

[0064] Swimming tub (homemade), restraint cage, beaker, glass rod, rat gavage needle.

[0065] 1.3 Modeling Method

[0066] The method for establishing the CFS rat model was referenced in the literature, employing a multi-factor modeling method with modifications. The modeling period lasted 21 days.

[0067] Except for the blank group, rats in the model control group and treatment group were forced to swim with a weight (calculated as 5% of the body weight of each rat) on the morning of each day: the rats swam in a pool with a water depth of 70 cm and a water temperature of 25℃, twice a day, with a 10-minute interval between each session, until they were exhausted. The criteria for exhaustion were a gradually decreasing swimming range, obvious incoordination and panic, the nose bobbing up and down on the water surface, and the head being submerged for 10 seconds without surfacing. At 12 noon on even-numbered days, the bottom bedding in the cage was removed and replaced with fresh water, with the water depth sufficient to cover the rats' heads and limbs, to prevent the rats from sleeping normally. The rats were removed at 8 am the next morning, for a total of 20 hours of sleep deprivation.

[0068] In addition, unpredictable stress methods were used daily, including tail clamping provocation, chronic restraint, and foot shock. One of these stimuli was randomly administered each day to prevent the rats from anticipating the occurrence of the stimulus and thus avoid adaptation. Tail clamping provocation: The rat's tail was clamped with a clamp 1-2 cm away from the tail root, to a tolerable degree without falling off, for 1 minute; chronic restraint: The rat was restrained with a restraint device for 1 hour; foot shock: 1 mA, 30V foot shock was administered 5 times, once every 1 minute, for 30 seconds each time.

[0069] 1.4 Drug preparation and administration

[0070] Drug preparation: Astragalus membranaceus 30g, American ginseng 12g, Agrimonia pilosa 30g, all packaged medicinal slices. All drugs used in the research were purchased from the pharmacy of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine. The medicinal materials are of effective and safe quality. After steeping in hot water, let stand at room temperature, then administer warm via gavage.

[0071] The formula for converting drug dosage using the equivalent dose factor is as follows:

[0072] D 大鼠 =D 人 ×(HI) 大鼠 / HI 人 ))×(W 大鼠 / W 人 )2 / 3

[0073] D: Dosage, g / (kg·d); HI: Body type coefficient; W: Body weight (kg).

[0074] The calculated dosage was as follows: Rats in the treatment group were administered the drug via gavage daily at a dosage of 2.7 g / kg body weight (calculated based on the amount of raw drug). The adult clinical dosage (raw drug) is 30.00 g / day. Based on an adult body weight of 70.0 kg being equivalent to 200 g in rats: D 大鼠 (g / d)=D×0.018=30.00g / d×0.018=0.54g / d; D 大鼠[g / (kg·d) ]=0.54g / d÷0.2kg=2.7g / (kg·d).

[0075] The specific grouping and administration are as follows: the normal group was fed according to routine, the model control group was given physiological saline by gavage, and the treatment group was given the drug of this application at 2.7g / kg by gavage. The administration time was from 9 to 11 am every day for 3 consecutive weeks.

[0076] 1.5 Observation Indicators and Detection Methods

[0077] General conditions: Animal weight, coat color, activity level, and mental state were measured and observed before and after the experiment. A semi-quantitative scoring scale (see Table 1) was used to observe the condition of rats in each group before and after the experiment. A score ≥4 was the criterion for determining the establishment of a fatigue model. The evaluation was conducted by two experimenters, and the average score was taken.

[0078] Table 1 Semi-quantitative rating scale for general condition of rats

[0079] Score mental state skin and hair Ear tail color stool 0 Quick-witted, lively and active, with bright eyes The skin is tightly connected to the fat, making it supple and elastic, with shiny and smooth fur. rosy luster Dry, formed feces 1 Slightly sluggish response, reduced spontaneous activity The skin is slightly loose and soft with reduced tension, and the hair is dry, yellow, and dull. Pale red with little luster Stool is sticky, soft, and has a shape. 2 Lethargy, listlessness, low spirits, curled-up limbs, and slow movements Loose skin with little fat, easily grasped; dry or tangled hair, lacking luster. Pale and lacking luster The stool is not formed, but not loose. 3 Listlessness, disappearance of aggressive and confrontational behavior The skin is loose, with no subcutaneous fat, and feels like bone when scratched; the body hair is dry, sparse, and falling out. Pale or bluish The stool is loose, greenish-brown, sticky, and foul-smelling.

[0080] Exhaustion swimming experiment: The degree of fatigue in rats was observed, and the time from entering the water to swimming to exhaustion was recorded for the three groups of animals before modeling, on the 21st day of modeling (the last day of modeling), and on the 21st day of drug administration (the last day of drug administration).

[0081] 2. Experimental Results

[0082] 2.1 General Comparison

[0083] Before modeling, all three groups of rats were in good general condition, with a semi-quantitative score of 0. Three weeks after modeling, five rats died, including three in the model control group and two in the treatment group. Compared to the control group, both the model control and treatment groups showed varying degrees of sparse hair, pale ear margins, reduced food intake, decreased activity, and loose stools. Their general condition semi-quantitative scores were all above 4 (P < 0.05), indicating successful modeling. On days 7, 14, and 21 after drug administration, the rats in each group were re-evaluated. Compared to the model control group, the treatment group showed significantly improved general condition, with significantly lower general condition semi-quantitative scores (P < 0.05). The experimental results are shown below. Figure 1 .

[0084] 2.2 Comparison of results from the exhaustion swimming experiment

[0085] Before modeling, each rat underwent an exhaustive swimming test. There was no significant difference in the exhaustive swimming time among the three groups (P > 0.05). Twenty-one days after modeling, compared with the control group, the exhaustive swimming time in both the model control group and the treatment group was significantly shorter (P < 0.05). The rats exhibited incoordination and panic more quickly in the swimming pool, indicating successful modeling. After three weeks of treatment, the exhaustive swimming time in the treatment group was significantly longer than that in the model group (P < 0.05), while there was no significant difference in exhaustive swimming time between the two groups compared to the control group (P > 0.05). This indicates that the treatment group can improve exercise endurance and alleviate fatigue in CFS rats. The results are shown in Table 2.

[0086] Table 2 Comparison of the duration of exhaustive swimming in each group of rats ( )

[0087] Group Before modeling Modeling in 21 days Administered for 21 days Blank group 82.60±6.42 81.13±6.63 80.87±5.94 Model control group 82.85±5.89 46.54±6.78 43.75±9.65 Treatment group 82.92±6.44 46.83±7.77 80.92±4.83

[0088] Depend on Figure 1 The experimental results in Table 2 show that the herbal tea bag prepared in this application can improve the general condition of rats with chronic fatigue syndrome and enhance the exercise endurance of fatigued rats.

[0089] Typical Case:

[0090] Case 1: Patient Zhou, female, 42 years old, presented on July 25, 2022, with the chief complaint of "general weakness for half a year." The patient reported that she had experienced general weakness without any obvious cause for the past six months, occasionally accompanied by palpitations, excessive sweating, aversion to activity, or worsening fatigue after slight activity, muscle soreness, and no relief after rest. She had consulted several hospitals, and all physical examination indicators were normal. Brief physical examination revealed: clear consciousness and fluent speech; normal muscle strength and tone in the limbs; no other significant abnormalities. Her complexion was pale, her tongue was pale red with a thin white coating, and her pulse was thready. The patient's persistent fatigue, lasting for more than 3 months, and after ruling out various diseases, met the diagnostic criteria for chronic fatigue syndrome. She was prescribed the herbal tea bag prepared in Example 4 of this application, containing 30g of Astragalus membranaceus, 12g of American ginseng, and 30g of Agrimonia pilosa, for 14 doses. Astragalus membranaceus enters the spleen and lung meridians, tonifies the middle energizer and replenishes qi, raises yang and lifts prolapse, and is a "key medicine for tonifying qi". American ginseng is cool in nature and moist in texture, tonifies qi and nourishes yin, clears heat and generates fluids. Agrimonia pilosa is bitter and astringent in taste, enters the heart and liver meridians, and is known as "the herb of exhaustion", which can relieve muscle fatigue.

[0091] Follow-up visit on August 15, 2022: After three weeks of taking the decoction as a tea substitute, the patient's symptoms of general weakness and excessive sweating were significantly reduced, their energy was more abundant, their exercise endurance was improved, their muscle soreness disappeared, and their fatigue could be relieved more quickly after exercise and rest. The patient was instructed to continue taking the original decoction as a tea substitute.

[0092] A follow-up phone call one month later revealed that the patient reported a lack of energy and that the fatigue symptoms had largely disappeared. The patient was still using the tea bag, albeit at a slightly reduced frequency, and did not require further hospital visits.

[0093] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the invention by those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the invention should be included within the scope of protection of the invention.

Claims

1. A traditional Chinese medicine tea bag for relieving chronic fatigue syndrome, characterized in that, The raw medicinal materials include the following parts by weight: Astragalus membranaceus 20-40 parts, American ginseng 5-20 parts, and Agrimonia pilosa 20-40 parts.

2. The herbal tea bag for relieving chronic fatigue syndrome according to claim 1, characterized in that, The raw medicinal materials include the following parts by weight: Astragalus membranaceus 24-36 parts, American ginseng 8-17 parts, and Agrimonia pilosa 24-36 parts.

3. The herbal tea bag for relieving chronic fatigue syndrome according to claim 1, characterized in that, The raw medicinal materials include the following parts by weight: Astragalus membranaceus 28-32 parts, American ginseng 10-15 parts, and Agrimonia pilosa 28-32 parts.

4. The herbal tea bag for relieving chronic fatigue syndrome according to any one of claims 1 to 3, characterized in that, The herbal tea bags also include pharmaceutically acceptable excipients.

5. The herbal tea bag for relieving chronic fatigue syndrome according to claim 4, characterized in that, The herbal tea bags are brewed with boiling water.

6. The application of a traditional Chinese medicine tea bag for relieving chronic fatigue syndrome as described in claim 4 in the treatment of chronic fatigue syndrome.

7. A method for preparing a traditional Chinese medicine tea bag as described in claim 4, characterized in that, Includes the following steps: Step 1: Weigh the raw medicinal materials according to the weight ratio, clean, dry, cut, and mix evenly; Step 2: Grind the raw medicinal materials processed in Step 1 into a fine powder and sieve it through a Chinese medicine sieve; Step 3: Divide and package the fine powder from Step 2.

8. The preparation method according to claim 7, characterized in that, The fine powder has a particle size of 100-200 mesh.

9. The preparation method according to claim 7, characterized in that, In step three, the fine powder is packaged into filter paper bags, which are made of one of the following: ordinary plastic non-woven fabric, corn fiber, plant fiber, food-grade nylon mesh, or PLA biodegradable environmentally friendly material.

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