Safe laboratory mouse anesthesia device

Abstract

The invention provides a safe laboratory mouse anesthesia device which comprises an anesthesia box, an opening is formed in the bottom of the anesthesia box, a rotatable laboratory mouse state detection mechanism is arranged on the bottom face of the anesthesia box, the laboratory mouse state detection mechanism is used for monitoring pressure generated by a laboratory mouse, and a pressure plate driving mechanism is arranged on the outer surface of the anesthesia box. During use, the laboratory mouse state detection mechanism is arranged at the bottom of the anesthesia box to support a laboratory mouse, and whether the laboratory mouse is in a standing state or a lying state is judged according to different contact areas of the laboratory mouse and the laboratory mouse state detection mechanism when the laboratory mouse stands and lies down through pressure values of unit areas; and when the laboratory mouse is in an anesthetic state, the laboratory mouse state detection mechanism is driven by the pressure plate driving mechanism to rotate to release the laboratory mouse, so that excessive anesthesia of the laboratory mouse is avoided, and the effect of improving the anesthesia safety is achieved.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of biological experimental devices, in particular to a safe experimental mouse anesthesia device. BACKGROUND

[0002] In the field of medicine and medical science, live experiments are often needed to verify experimental data and obtain live data. Commonly used live samples in experiments are rabbits, mice and the like. Among them, the use of mice has a lower cost than other live animals, so mice are often the first choice for live experiments.

[0003] Based on humanitarianism and the convenience of operation, experimental mice are often anesthetized before live experiments. According to the type of anesthesia, it can be divided into injection anesthesia and gas anesthesia. Among them, gas anesthesia is more convenient and has lower cost. When anesthetizing experimental mice, because of the different sizes and physical qualities of mice, the same dose of anesthetic may cause the death of experimental mice, increasing the cost and sample loss of experiments.

[0004] Therefore, the present application provides a safe experimental mouse anesthesia device to reduce the mortality of experimental mice during anesthesia. SUMMARY

[0005] In view of the above-mentioned shortcomings of the prior art, the purpose of the present application is to provide a safe experimental mouse anesthesia device to solve the problem that experimental mice are easily killed during anesthesia due to individual differences.

[0006] To achieve the above-mentioned purposes and other related purposes, the present application provides a safe experimental mouse anesthesia device, which comprises an anesthesia box, the bottom of the anesthesia box is provided with an opening, the bottom surface of the anesthesia box is a rotatable experimental mouse state detection mechanism, the experimental mouse state detection mechanism is used for monitoring the pressure generated by the experimental mouse, the outer surface of the anesthesia box is provided with a pressure plate driving mechanism, and the pressure plate driving mechanism is used for controlling the rotation of the experimental mouse state detection mechanism.

[0007] The outer surface of the anesthesia box is provided with a data processing component, and the data processing component is respectively connected with the experimental mouse state detection mechanism and the pressure plate driving mechanism.

[0008] The experimental mouse state detection mechanism transmits the experimental mouse pressure information to the data processing component, the data processing component judges the experimental mouse posture information according to the pressure in the unit area of the experimental mouse, and controls the start and stop of the pressure plate driving mechanism.

[0009] The data processing component comprises a logic instruction module, a solenoid valve control module, a power start-stop module and a pressure plate driving control module, the logic instruction module is used for information interaction and outputs control instructions to the solenoid valve control module, the power start-stop module and the pressure plate driving control module.

[0010] Preferably, the anesthesia box comprises an experimental mouse container, the bottom of the experimental mouse container is provided with an opening, the outer surface of the experimental mouse container is respectively provided with a anesthesia gas access channel and a ventilation channel, the anesthesia gas access channel and the ventilation channel are respectively provided with a solenoid valve one and a solenoid valve two;

[0011] The solenoid valve one and the solenoid valve two are both signal connected with a data processing component, and the solenoid valve one and the solenoid valve two can be controlled independently;

[0012] The bottom of the experimental mouse container is provided with a support base, and the support base makes the bottom of the experimental mouse container suspended.

[0013] Preferably, the top of the experimental mouse container is provided with a sealing cover, and the sealing cover is opened by turning up.

[0014] Preferably, the top of the experimental mouse container is provided with a human-computer interaction component, and the human-computer interaction component is signal connected with a data processing component.

[0015] Preferably, the four side walls of the experimental mouse container are transparent.

[0016] Preferably, the four side walls of the experimental mouse container are provided with a sandwich layer, and the wires of the solenoid valve one, the solenoid valve two and the human-computer interaction component are led to the data processing component through the sandwich layer of the four side walls of the experimental mouse container.

[0017] Preferably, the experimental mouse state detection mechanism comprises a pressure detection plate, the side surface of the pressure detection plate is provided with a hinged rod, and the connection part of the pressure detection plate and the hinged rod is provided with a junction box;

[0018] The junction box is signal connected with a data processing component.

[0019] The side surface of the experimental mouse container is provided with a pressure plate mounting seat, the hinged rod cooperates with the pressure plate mounting seat to support the pressure detection plate, and the pressure detection plate is turned over with the hinged rod as the pivot;

[0020] The outer surface of the hinged rod is provided with a driving connection plate, and the driving connection plate is connected with the output end of a pressure plate driving mechanism.

[0021] Preferably, the top of the pressure detection plate is provided with an electric shock component, and the electric shock component is flush with the top of the pressure detection plate.

[0022] The electric shock component is electrically connected with the data processing component.

[0023] Preferably, the pressure plate driving mechanism comprises a driver, an output end of the driver is provided with a telescopic rod, and an outer surface of the telescopic rod is provided with a thread line;

[0024] The telescopic rod penetrates through a driving connecting plate, and the telescopic rod is fixed on the driving connecting plate through cooperation of the thread line and a fastener.

[0025] Preferably, the pressure detection plate is used for monitoring a state of a surface pressure thereof in real time, and real-time transmission of acquired pressure data to a logic instruction module;

[0026] The logic instruction module is used for judging a state of the experimental mouse according to a pre-set pressure threshold value, and simultaneously transmitting pressure information to the human-computer interaction component in real time, so that the human-computer interaction component can display pressure data in real time.

[0027] When the pressure data transmitted by the pressure detection plate to the logic instruction module is floating data or pressure points are dispersed and unit area pressure is large, the logic instruction module judges that the experimental mouse is in an active state and a stationary standing state.

[0028] When the pressure data transmitted by the pressure detection plate to the logic instruction module is stationary, and a pressure range increases and unit pressure decreases, the logic instruction module judges that the experimental mouse is in a lying state, at this time, the logic instruction module sends a closing instruction and an opening instruction to the electromagnetic valve one and the electromagnetic valve two respectively through the electromagnetic valve control module, and the electromagnetic valve one and the electromagnetic valve two cut off the input of the anesthetic gas and the output of the anesthetic gas in the experimental mouse container.

[0029] Meanwhile, the logic instruction module sends an opening instruction to the power start-stop module, so that the power start-stop module briefly electrifies the electric shock component, and the experimental mouse is stimulated by the instantaneous current, at this time, the logic instruction module outputs instructions according to the following conditions.

[0030] If the pressure detection plate generates obvious pressure data change, the logic instruction module judges that the experimental mouse is not completely anesthetized, at this time, the logic instruction module sends an instruction to the electromagnetic valve control module, the electromagnetic valve control module controls the electromagnetic valve two to be closed and the electromagnetic valve one to be opened respectively, continues to input the anesthetic gas to anesthetize the experimental mouse, and continues to monitor the state of the experimental mouse through the pressure detection plate, and repeats the above instructions.

[0031] Otherwise, the logic instruction module sends an instruction to the pressure plate driving control module, the driver is started through the pressure plate driving control module, the telescopic rod drives the pressure detection plate to overturn, and the experimental mouse slides out of the inside of the experimental mouse container under the action of gravity.

[0032] As described above, the safe experimental mouse anesthesia device of the present application has the following beneficial effects:

[0033] 1、The experimental mouse state detection mechanism is arranged at the bottom of the anesthesia box to support the experimental mouse, and the standing state or lying state of the experimental mouse is determined according to the different contact areas of the experimental mouse with the experimental mouse state detection mechanism when the experimental mouse stands or lies, so as to determine whether the experimental mouse is anesthetized, and when the experimental mouse is in an anesthetized state, the experimental mouse state detection mechanism is driven to rotate by the pressure plate driving mechanism to release the experimental mouse, avoiding excessive anesthesia of the experimental mouse, and achieving the effect of improving anesthesia safety.

[0034] 2、The electric shock component is installed on the pressure detection plate, and when the experimental mouse is in a lying state, the experimental mouse can be stimulated by the electric shock component to confirm the anesthesia state of the experimental mouse, avoiding misjudgment of the device due to death and the like, and achieving the effect of improving the accuracy of the device.

[0035] 3、The anesthesia gas access channel and the air exchange channel are arranged on the side of the experimental mouse container respectively, and the on-off of the anesthesia gas access channel and the air exchange channel is controlled by the electromagnetic valve one and the electromagnetic valve two respectively, the input amount of anesthesia gas can be controlled by the electromagnetic valve one during use, and when the experimental mouse is in an anesthetized or suspected anesthetized state, the input of anesthesia gas is cut off and the circulation of air in the experimental mouse container is increased to dilute the anesthesia gas, achieving the effects of facilitating control of anesthesia gas input amount and further improving equipment safety.

[0036] 4、The hinge rod is arranged on the side of the pressure detection plate, the pressure plate mounting seat is connected with the experimental mouse container, and the turning of the pressure detection plate is realized by driving the connecting plate through the extension and retraction of the telescopic rod, achieving the effects of simple structure, low manufacturing cost and low failure rate.

[0037] Therefore, the present application effectively overcomes the various shortcomings in the prior art and has high industrial utilization value. BRIEF DESCRIPTION OF DRAWINGS

[0038] Figure 1 The structure of the present application is shown.

[0039] Figure 2 The structure of the present application is shown.

[0040] Figure 3 The structure of the present application Figure 1 is shown.

[0041] Figure 4 The structure of the experimental mouse state detection mechanism of the present application is shown.

[0042] Figure 5 The figure shows the workflow of the present application.

[0043] Element number explanation:

[0044] 1. anesthesia box; 11. experimental mouse container; 12. anesthesia gas access channel; 13. ventilation channel; 14. electromagnetic valve 1; 15. electromagnetic valve 2; 16. sealing cover; 17. pressure plate mounting seat; 18. support base;

[0045] 2. experimental mouse state detection mechanism; 21. pressure detection plate; 22. hinged rod; 23. junction box; 24. electric shock component; 25. drive connecting plate;

[0046] 3. pressure plate drive mechanism; 31. driver; 32. telescopic rod; 33. threaded line;

[0047] 4. data processing component;

[0048] 5. human-computer interaction component. DETAILED DESCRIPTION

[0049] The following describes the embodiments of the present application by specific examples, and those skilled in the art can easily understand other advantages and effects of the present application from the content disclosed in the specification.

[0050] Please refer to Figures 1 to 5 . It should be understood that the structure, proportion, size, etc. shown in the drawings attached to the specification are only used to cooperate with the content disclosed in the specification for those skilled in the art to understand and read, and are not used to limit the defined conditions that the present application can be implemented, so they do not have technical substantive significance. Any modification of the structure, change of the proportion relationship, or adjustment of the size, without affecting the effects that the present application can produce and the purposes that the present application can achieve, should still fall within the scope of the technical content disclosed by the present application. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" in the specification are only for the convenience of clear description, and are not used to limit the scope of the present application, the change or adjustment of the relative relationship, without substantial changes in technical content, is also considered as the scope of the present application.

[0051] As Figure 1As shown, the present application provides a safe experimental mouse anesthesia device, which comprises an anesthesia box 1 for limiting the activity space of the experimental mouse. The bottom surface of the anesthesia box 1 is a rotatable experimental mouse state detection mechanism 2. The experimental mouse state detection mechanism 2 is used for monitoring the pressure generated by the experimental mouse and sealing the opening at the bottom of the anesthesia box 1. The outer surface of the anesthesia box 1 is provided with a pressure plate driving mechanism 3 for controlling the rotation of the experimental mouse state detection mechanism 2. When the experimental mouse state detection mechanism 2 is in a horizontal state, the bottom of the anesthesia box 1 is sealed, so that the anesthesia gas can fill the inside of the anesthesia box 1. When the experimental mouse state detection mechanism 2 is turned down, the sealing state of the anesthesia box 1 is released, so that the anesthesia gas is discharged. And the experimental mouse is driven by gravity along the experimental mouse state detection mechanism 2 to slide out of the inside of the anesthesia box 1, avoiding the experimental mouse being over-anesthetized.

[0052] The outer surface of the anesthesia box 1 is provided with a data processing component 4, which contains a power supply module for power supply, a controller for processing information and instructions, and a circuit board required for installing the above components. The power supply module is a POL (Power on Load) power supply system or a PUPS (Point of Use Power Supply) and the like. The processor is an ARM (Advanced RISC Machines) controller, an FPGA (Field Programmable Gate Array) controller, a SoC (System on Chip) controller, a DSP (Digital Signal Processing) controller or an MCU (Micorcontroller Unit) controller and the like. The data processing component 4 is respectively connected with the experimental mouse state detection mechanism 2 and the pressure plate driving mechanism 3 in signal, for receiving and transferring the information data of the experimental mouse state detection mechanism 2 and the pressure plate driving mechanism 3, and supplying power to the experimental mouse state detection mechanism 2 and the pressure plate driving mechanism 3 through the power supply module respectively.

[0053] The experimental mouse state detection mechanism 2 transmits the experimental mouse pressure information to the data processing component 4, and the data processing component 4 judges the experimental mouse posture information according to the pressure in the unit area of the experimental mouse, and controls the pressure plate driving mechanism 3 to start and stop according to the pressure information. When the experimental mouse is in a standing or moving state, the limbs of the experimental mouse are in contact with the top of the experimental mouse state detection mechanism 2, the contact area of the experimental mouse and the experimental mouse state detection mechanism 2 is small, and the pressure per unit area is large. When the experimental mouse is in a state of anesthesia, the experimental mouse is mostly lying down and turning over. At this time, the contact area of the experimental mouse and the experimental mouse state detection mechanism 2 is larger, and the pressure per unit area is smaller. According to the above principle, whether the experimental mouse is anesthetized is judged. The pressure plate driving mechanism 3 drives the experimental mouse state detection mechanism 2 to turn over after the experimental mouse is anesthetized, so that the experimental mouse quickly leaves the inside of the anesthesia box 1. Avoiding that the anesthesia gas in the anesthesia box 1 causes excessive anesthesia to the experimental mouse and causes the experimental mouse to die.

[0054] The data processing component 4 includes a logic instruction module, an electromagnetic valve control module, a power start-stop module, and a pressure plate driving control module. The logic instruction module is used for information interaction and outputs control instructions to the electromagnetic valve control module, the power start-stop module, and the pressure plate driving control module. According to the set threshold, the working of each component is controlled to realize intelligent operation.

[0055] As shown in Figure 1 some embodiments, the anesthesia box 1 of the present application includes an experimental mouse container 11 for restricting the activity space of the experimental mouse. The bottom of the experimental mouse container 11 is provided with an open port, and the top of the experimental mouse container 11 is in a semi-closed state. The outer surface of the experimental mouse container 11 is respectively provided with a anesthesia gas access channel 12 and an air exchange channel 13. The anesthesia gas access channel 12 is used for inputting anesthesia gas. The air exchange channel 13 is used for increasing the air circulation inside the experimental mouse container 11 to dilute the anesthesia gas. The anesthesia gas access channel 12 and the air exchange channel 13 are respectively provided with electromagnetic valve one 14 and electromagnetic valve two 15. The flow of the anesthesia gas access channel 12 and the air exchange channel 13 can be controlled respectively through the electromagnetic valve one 14 and the electromagnetic valve two 15, so as to control the input amount of anesthesia gas and the dilution speed of anesthesia gas. The device can be more needed to realize more refined control. The electromagnetic valve one 14 and the electromagnetic valve two 15 are signal connected with the data processing component 4, so that the data processing component 4 can control the electromagnetic valve one 14 and the electromagnetic valve two 15 according to the data fed back by the experimental mouse state detection mechanism 2, so as to improve the intelligent degree of the equipment. The electromagnetic valve one 14 and the electromagnetic valve two 15 can be controlled separately, so as to be able to set parameters of the electromagnetic valve one 14 and the electromagnetic valve two 15 respectively according to the setting, and improve the convenience of use.

[0056] The bottom of the experimental mouse container 11 is provided with a support base 18, which suspends the bottom of the experimental mouse container 11. Through the support of the support base 18 to the experimental mouse container 11, the experimental mouse state detection mechanism 2 has a space for downward overturning, so as to avoid motion interference.

[0057] As shown in Figure 1 and Figure 2 , in some embodiments, the top of the experimental mouse container 11 of the application is provided with a sealing cover 16. The sealing cover 16 is used to seal the slot at the top of the experimental mouse container 11 where the experimental mouse is placed, so as to improve the air tightness inside the experimental mouse container 11. The sealing cover 16 is opened upward, and after the experimental mouse is placed, the sealing cover 16 will be sealed under the action of gravity. While achieving convenient operation, the sealing performance can be improved.

[0058] As shown in Figure 1 and Figure 2 , in some embodiments, the top of the experimental mouse container 11 of the application is provided with a human-computer interaction component 5, which is a touch display screen for human-computer interaction control. The human-computer interaction component 5 is signal connected with the data processing component 4, and the real-time data of the data processing component 4 can be displayed through the human-computer interaction component 5. At the same time, the human-computer interaction component 5 can also set the working parameters of the electromagnetic valve one 14, the electromagnetic valve two 15 and the pressure plate driving mechanism 3 through the data processing component 4.

[0059] As shown in Figure 1 , in some embodiments, the four walls of the experimental mouse container 11 are transparent. When the experimental mouse is anesthetized, the operator can directly observe the state of the experimental mouse through the transparent experimental mouse container 11. Manual observation can complement automatic equipment, and the experimental mouse can be rescued in time when the parameter setting is wrong.

[0060] As shown in Figure 1 , in some embodiments, the four walls of the experimental mouse container 11 are provided with a sandwich, and the wires of the electromagnetic valve one 14, the electromagnetic valve two 15 and the human-computer interaction component 5 are led to the data processing component 4 through the sandwich of the four walls of the experimental mouse container 11. By wiring in the sandwich of the experimental mouse container 11, the appearance of the device can be improved and the safety of the circuit can be improved.

[0061] As shown in Figure 1 and Figure 4As shown, in some embodiments, the experimental mouse state detection mechanism 2 includes a pressure detection plate 21, which is a strain pressure sensor, a piezoresistive pressure sensor, a capacitive pressure sensor, etc. The pressure value and distribution on the surface are measured by converting into an electrical signal through a Wheatstone bridge, changing the distance or area between the capacitor plates through pressure, or changing the capacitance in other ways. Whether the experimental mouse is anesthetized is determined according to the concentration of pressure when the experimental mouse stands and the dispersion of pressure when the experimental mouse lies down. The side of the pressure detection plate 21 is provided with a hinged rod 22, which is a smooth circular column. The connection between the pressure detection plate 21 and the hinged rod 22 is provided with a junction box 23, and one end of the wire in the junction box 23 is connected with the pressure detection plate 21. The other end of the wire in the junction box 23 is connected with the data processing component 4, so that the pressure detection plate 21 is powered and signal interaction is performed through the data processing component 4.

[0062] The side of the experimental mouse container 11 is provided with a pressure plate mounting seat 17, and the number of the pressure plate mounting seat 17 is two. The two pressure plate mounting seats 17 are connected and supported with the hinged rod 22 from both ends of the hinged rod 22, so that the pressure detection plate 21 can be flipped with the hinged rod 22 as the pivot.

[0063] The outer surface of the hinged rod 22 is provided with a driving connection plate 25, which is connected with the output end of the pressure plate driving mechanism 3. When the pressure plate driving mechanism 3 applies pressure to the driving connection plate 25, the driving connection plate 25 drives the hinged rod 22 to rotate by changing the angle, so as to realize the rotation of the pressure detection plate 21. The opening and closing of the bottom opening of the experimental mouse container 11 is controlled through the rotation of the pressure detection plate 21. When the pressure detection plate 21 monitors that the experimental mouse is anesthetized, the data is transmitted to the data processing component 4, and the control instruction is sent to the pressure plate driving mechanism 3 through the data processing component 4, so as to start the pressure plate driving mechanism 3 to drive the pressure detection plate 21 to flip.

[0064] As shown in FIG. 2, the experimental mouse state detection mechanism 2 includes a pressure detection plate 21, a hinged rod 22, a junction box 23, a pressure plate driving mechanism 3, and a data processing component 4. Figure 1 and Figure 4As shown in the figure, in some embodiments, the top of the pressure detection plate 21 is provided with an electric shock component 24. The experimental mouse is stimulated by the electric shock component 24 to determine whether the experimental mouse is dead or not, so as to improve the accuracy of the equipment judgment. The electric shock component 24 is a bare metal wire or metal strip. When the electric shock component 24 is electrified, an electric current for stimulating the experimental mouse is generated. The specific working principle of the electric shock component 24 can refer to the electric mosquito swatter. The electric shock component 24 is flush with the top of the pressure detection plate 21, which is used to avoid the electric shock component 24 being bitten by the experimental mouse, so as to improve the service life of the electric shock component 24. The electric shock component 24 is electrically connected with the data processing component 4. When the data processing component 4 receives the information that the experimental mouse is anesthetized, the data processing component 4 will supply power to the electric shock component 24 for a short time, so that the electric shock component 24 can instantaneously shock the experimental mouse. In this way, the experimental mouse is stimulated, and at the same time, the harm to the experimental mouse is avoided.

[0065] As shown in the figure, Figure 1 and Figure 3 As shown in the figure, in some embodiments, the pressure plate driving mechanism 3 comprises a driver 31, which can be an electric push rod. The output end of the driver 31 is provided with a telescopic rod 32. The outer surface of the telescopic rod 32 is provided with a threaded line 33.

[0066] A straight slot is formed in the driving connection plate 25, and the telescopic rod 32 penetrates the straight slot in the driving connection plate 25. The telescopic rod 32 is connected with the driving connection plate 25 through the threaded line 33 and fasteners such as nuts from both sides of the driving connection plate 25. When the telescopic rod 32 exerts force on the driving connection plate 25, the articulated rod 22 drives the pressure detection plate 21 to rotate upward, so that the pressure detection plate 21 seals the bottom of the experimental mouse container 11. When the telescopic rod 32 drives the driving connection plate 25 to retract, the articulated rod 22 drives the pressure detection plate 21 to rotate downward, so that the opening below the experimental mouse container 11 is exposed, which is used to discharge the anesthetic gas in the experimental mouse container 11 and convey the experimental mouse out.

[0067] As shown in the figure, Figure 5 The specific use process of the present application is as follows:

[0068] The body size data of the experimental mouse is measured to determine the amount of anesthetic gas used and the pressure data of the experimental mouse. The flow rate and pressure threshold of the electromagnetic valve one 14 are set through the man-machine interaction component 5 according to the body size data of the experimental mouse. In this way, the over-input of anesthetic gas is avoided, and the sensitivity of the pressure detection plate 21 in judging the shape of the experimental mouse is improved.

[0069] The experimental mouse is placed in the experimental mouse container 11, and the experimental mouse is in contact with the pressure detection plate 21 at the bottom of the experimental mouse container 11. The pressure value of the experimental mouse is detected by the pressure detection plate 21. The top of the experimental mouse container 11 is sealed by the sealing cover 16 to improve the sealing of the inside of the experimental mouse container 11, so that the anesthetic gas can act faster.

[0070] The anesthetic gas is continuously input from the outside anesthetic gas output device to the inside of the experimental mouse container 11 at the anesthetic gas access channel 12, so that the anesthetic gas can quickly fill the inside of the experimental mouse container 11, thereby anesthetizing the laboratory.

[0071] The pressure detection plate 21 monitors the state of the pressure in real time, and transmits the pressure information to the human-computer interaction component 5 in real time through the data processing component 4. The pressure data and the input amount of anesthetic gas are displayed in real time at the human-computer interaction component 5.

[0072] When the pressure detection plate 21 detects that the experimental mouse is in a lying state, the data processing component 4 respectively sends closing instructions and opening instructions to the electromagnetic valve one 14 and the human-computer interaction component 5. The input of anesthetic gas is cut off, and the anesthetic gas in the experimental mouse container 11 is discharged to dilute the anesthetic gas in the experimental mouse container 11, so as to avoid excessive anesthesia of the experimental mouse and cause the death of the experimental mouse. At the same time, the data processing component 4 energizes the electric shock component 24 to stimulate the experimental mouse through current, so as to determine whether the experimental mouse is in an anesthetized state or a dead state.

[0073] If the experimental mouse moves under the current stimulation, the pressure data of the pressure detection plate 21 will be jittered. At this time, the data processing component 4 sends instructions to close the electromagnetic valve two 15 and open the electromagnetic valve one 14, so that the experimental mouse container 11 is kept sealed, and the anesthetic gas continues to be input to anesthetize the experimental mouse.

[0074] Otherwise, the data processing component 4 sends a start instruction to the driver 31 to drive the pressure detection plate 21 to flip through the telescopic rod 32, so that the bottom of the experimental mouse container 11 is unsealed. At this time, a large amount of external air will flow into the inside of the experimental mouse container 11 to dilute the anesthetic gas. At the same time, the experimental mouse slides out of the inside of the experimental mouse container 11 along the pressure detection plate 21 under the action of gravity, so as to facilitate the operator to take the experimental mouse.

[0075] The specific working principle is as follows:

[0076] The pressure detection plate 21 monitors the state of the pressure on its surface in real time, and transmits the obtained pressure data to the logical instruction module in real time;

[0077] The logic instruction module judges the state of the experimental mouse according to the preset pressure threshold, and simultaneously transmits the pressure information to the man-machine interaction component 5 in real time, so that the man-machine interaction component 5 can display the pressure data in real time.

[0078] When the pressure data transmitted by the pressure detection plate 21 to the logic instruction module is floating data or the pressure points are dispersed and the unit area pressure is large, the logic instruction module judges that the experimental mouse is in an active state and a stationary standing state.

[0079] When the pressure data transmitted by the pressure detection plate 21 to the logic instruction module is stationary, and the pressure range increases and the unit pressure decreases, the logic instruction module judges that the experimental mouse is in a lying state. At this time, the logic instruction module sends closing instructions and opening instructions to the electromagnetic valve one 14 and the electromagnetic valve two 15 respectively through the electromagnetic valve control module, and cuts off the input of the anesthetic gas and the output of the anesthetic gas in the experimental mouse container 11 through the electromagnetic valve one 14 and the electromagnetic valve two 15.

[0080] Meanwhile, the logic instruction module sends an opening instruction to the power start-stop module, so that the power start-stop module briefly powers on the electric shock component 24, and stimulates the experimental mouse through the instantaneous current. At this time, the logic instruction module outputs instructions according to the following conditions.

[0081] If the pressure detection plate 21 generates obvious pressure data changes, the logic instruction module judges that the experimental mouse is not completely anesthetized. At this time, the logic instruction module sends instructions to the electromagnetic valve control module, and the electromagnetic valve control module controls the electromagnetic valve two 15 to close and the electromagnetic valve one 14 to open respectively, continues to input anesthetic gas to anesthetize the experimental mouse, and continues to monitor the state of the experimental mouse through the pressure detection plate 21, and repeats the above instructions.

[0082] Otherwise, the logic instruction module sends instructions to the pressure plate driving control module, and starts the driver 31 through the pressure plate driving control module to drive the pressure detection plate 21 to flip through the telescopic rod 32, so that the experimental mouse slides out of the inside of the experimental mouse container 11 under the action of gravity.

[0083] In summary, the safe experimental mouse anesthetizing device of the present application supports the experimental mouse through the experimental mouse state detection mechanism 2 arranged at the bottom of the anesthetic box 1, and judges whether the experimental mouse is in a standing state or a lying state according to the different contact areas of the experimental mouse with the experimental mouse state detection mechanism 2 when the experimental mouse stands and lies, so as to judge whether the experimental mouse is anesthetized. When the experimental mouse is in an anesthetized state, the experimental mouse is discharged by driving the experimental mouse state detection mechanism 2 to rotate through the pressure plate driving mechanism 3, so as to avoid excessive anesthesia of the experimental mouse, and the effect of improving anesthesia safety is achieved.

[0084] The present application installs the electric shock component 24 on the pressure detection plate 21, and when the experimental mouse is in a lying state, the experimental mouse can be stimulated by the electric shock component 24 to confirm the anesthesia state of the experimental mouse, avoid the device misjudgment caused by the experimental mouse pretending to be dead, and improve the accuracy of device judgment.

[0085] The present application sets the anesthetic gas access channel 12 and the air exchange channel 13 on the side of the experimental mouse container 11 respectively, and controls the on-off of the anesthetic gas access channel 12 and the air exchange channel 13 by the electromagnetic valve one 14 and the electromagnetic valve two 15 respectively, so that the input amount of anesthetic gas can be controlled by the electromagnetic valve one 14 during use, and when the experimental mouse is in an anesthesia or suspected anesthesia state, the input of anesthetic gas is cut off and the circulation of air inside the experimental mouse container 11 is increased to dilute the anesthetic gas, thereby achieving the effects of convenient control of anesthetic gas input and further improving the safety of the equipment.

[0086] The present application sets the hinged rod 22 on the side of the pressure detection plate 21, connects the pressure plate mounting seat 17 with the experimental mouse container 11, and realizes the overturning of the pressure detection plate 21 by the telescopic rod 32 to push the driving connecting plate 25, thereby achieving the effects of simple structure, low manufacturing cost and low failure rate.

[0087] Therefore, the present application effectively overcomes the various shortcomings in the prior art and has high industrial utilization value.

[0088] The above embodiments only exemplarily illustrate the principles and effects of the present application, and are not used to limit the present application. Any person skilled in the art can modify or change the above embodiments without departing from the spirit and scope of the present application. Therefore, all equivalent modifications or changes completed by those skilled in the art without departing from the spirit and technical thought disclosed by the present application should be covered by the claims of the present application.

Claims

1. A safe experimental mouse anesthetizing device, characterized by, The anesthesia box (1) is provided with an opening at the bottom, and the bottom surface is a rotatable experimental mouse state detection mechanism (2) for monitoring the pressure generated by the experimental mouse; the outer surface of the anesthesia box (1) is provided with a pressure plate driving mechanism (3) for controlling the rotation of the experimental mouse state detection mechanism (2); The outer surface of the anesthesia box (1) is provided with a data processing component (4) which is respectively connected with the experimental mouse state detection mechanism (2) and the pressure plate driving mechanism (3); The experimental mouse state detection mechanism (2) transmits the experimental mouse pressure information to the data processing component (4), which judges the experimental mouse posture information according to the pressure per unit area of the experimental mouse, and controls the start and stop of the pressure plate driving mechanism (3); The data processing component (4) contains a logic instruction module, an electromagnetic valve control module, a power on-off module and a pressure plate driving control module, which are used for information interaction and output control instructions to the electromagnetic valve control module, the power on-off module and the pressure plate driving control module.

2. The safe experimental mouse anesthesia apparatus according to claim 1, characterized by: The anesthesia box (1) includes an experimental mouse container (11) provided with an opening at the bottom, and the outer surface of the experimental mouse container (11) is respectively provided with a anesthesia gas access channel (12) and a ventilation channel (13), and the anesthesia gas access channel (12) and the ventilation channel (13) are respectively provided with an electromagnetic valve one (14) and an electromagnetic valve two (15); The electromagnetic valve one (14) and the electromagnetic valve two (15) are respectively connected with the data processing component (4), and the electromagnetic valve one (14) and the electromagnetic valve two (15) can be controlled independently; The bottom of the experimental mouse container (11) is provided with a support base (18) which makes the bottom of the experimental mouse container (11) suspended.

3. The safe laboratory mouse anesthesia apparatus according to claim 2, characterized by: The top of the experimental mouse container (11) is provided with a sealing cover (16) which is opened by turning up.

4. The safe laboratory mouse anesthesia apparatus according to claim 2, characterized by: The top of the experimental mouse container (11) is provided with a human-computer interaction component (5) which is connected with the data processing component (4).

5. The safe experimental mouse anesthesia apparatus according to claim 4, characterized by: The four walls of the experimental mouse container (11) are transparent.

6. The safe experimental mouse anesthesia apparatus according to claim 5, characterized by: The four walls of the experimental mouse container (11) are provided with a sandwich layer, and the wires of the electromagnetic valve one (14), the electromagnetic valve two (15) and the human-computer interaction component (5) are led to the data processing component (4) through the sandwich layer of the four walls of the experimental mouse container (11).

7. The safe experimental mouse anesthesia apparatus according to any one of claims 2-6, characterized in that: The experimental mouse state detection mechanism (2) includes a pressure detection plate (21) provided with a hinge rod (22) at the side, and a junction box (23) is arranged at the connection between the pressure detection plate (21) and the hinge rod (22); The junction box (23) is connected with the data processing component (4). The side of the experimental mouse container (11) is provided with a pressure plate mounting seat (17), the hinged rod (22) supports the pressure detection plate (21) in cooperation with the pressure plate mounting seat (17), and the pressure detection plate (21) is turned over with the hinged rod (22) as the pivot; The outer surface of the hinged rod (22) is provided with a driving connecting plate (25), and the driving connecting plate (25) is connected with the output end of the pressure plate driving mechanism (3).

8. The safe experimental mouse anesthesia apparatus according to claim 7, characterized by: The top of the pressure detection plate (21) is provided with an electric shock component (24) flush with the top of the pressure detection plate (21); The electric shock component (24) is electrically connected with the data processing component (4).

9. The safe experimental mouse anesthesia apparatus according to claim 7, characterized by: The pressure plate driving mechanism (3) comprises a driver (31), and the output end of the driver (31) is provided with a telescopic telescopic rod (32), and the outer surface of the telescopic telescopic rod (32) is provided with a threaded line (33); The telescopic telescopic rod (32) penetrates through the driving connecting plate (25), and the telescopic telescopic rod (32) is fixed on the driving connecting plate (25) through the threaded line (33) and the fastener.

10. The safe experimental mouse anesthesia device according to claim 7, wherein: The pressure detection plate (21) is used for monitoring the state of the surface pressure in real time, and transmitting the acquired pressure data to the logic instruction module in real time; The logic instruction module is used for judging the state of the experimental mouse according to the pre-set pressure threshold value, and transmitting the pressure information to the human-computer interaction component (5) in real time, so that the human-computer interaction component (5) can display the pressure data in real time; When the pressure data transmitted by the pressure detection plate (21) to the logic instruction module is floating data or the pressure points are dispersed and the unit area pressure is large, the logic instruction module judges that the experimental mouse is in the active state and the static standing state; When the pressure data transmitted by the pressure detection plate (21) to the logic instruction module is static, and the pressure range increases and the unit pressure decreases, the logic instruction module judges that the experimental mouse is in the lying state, at this time, the logic instruction module sends closing instructions and opening instructions to the electromagnetic valve one (14) and the electromagnetic valve two (15) respectively through the electromagnetic valve control module, and cuts off the input and output of the anesthetic gas in the experimental mouse container (11) through the electromagnetic valve one (14) and the electromagnetic valve two (15); At the same time, the logic instruction module sends an opening instruction to the power start-stop module, so that the power start-stop module briefly electrifies the electric shock component (24), and stimulates the experimental mouse through the instantaneous current, at this time, the logic instruction module outputs instructions according to the following conditions: If, the pressure detection plate (21) produces obvious pressure data change, the logic instruction module judges that the experimental mouse is not completely anesthetized, at this time, the logic instruction module sends instructions to the electromagnetic valve control module, the electromagnetic valve control module controls the electromagnetic valve two (15) to close and the electromagnetic valve one (14) to open respectively, continues to input anesthetic gas to anesthetize the experimental mouse, and continues to monitor the state of the experimental mouse through the pressure detection plate (21), and repeats the above instructions; Otherwise, the logic instruction module sends an instruction to the pressure plate driving control module, and the pressure plate driving control module controls the driver (31) to start, and the telescopic rod (32) drives the pressure detection plate (21) to flip, so that the experimental mouse slides out of the inside of the experimental mouse container (11) under the action of gravity.

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