Combined polyphenol nanocapsule powder with effect of efficiently regulating lipid metabolism and preparation method of combined polyphenol nanocapsule powder

The nanocapsule powder prepared by sodium caseinate and pectin solves the problems of low stability and bioavailability of polyphenolic compounds, achieves efficient lipid metabolism regulation, and is suitable for industrial mass production.

CN120899666APending Publication Date: 2025-11-07SOUTH CHINA UNIV OF TECH
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Patent Information

Application Number
CN202511056636.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-30
Publication Date
2025-11-07

AI Technical Summary

Technical Problem

Existing polyphenol compounds have low oral bioavailability and poor stability. Furthermore, existing microencapsulation technology involves complex procedures, low encapsulation efficiency, and poor storage stability, making it difficult to efficiently regulate lipid metabolism.

Method used

Sodium caseinate and pectin were used as wall materials. Nanocapsule powder was prepared by pH adjustment and spray drying technology to form sodium caseinate-pectin nanocomposite, which encapsulates flavonoids and phenolic acid polyphenols to form a core-shell structure, thereby increasing stability and bioavailability.

Benefits of technology

It improves the encapsulation efficiency, solubility, and stability of polyphenolic compounds, enhances the inhibitory effect on pancreatic lipase and α-glucosidase, achieves efficient lipid metabolism regulation, and is suitable for industrial mass production.

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Abstract

The invention discloses combined polyphenol nanocapsule powder with an effect of efficiently regulating lipid metabolism and a preparation method of the combined polyphenol nanocapsule powder, and belongs to the technical field of polyphenol processing and fat-reducing health. The preparation method of the combined polyphenol nanocapsule powder comprises the following steps: dissolving sodium caseinate and pectin in water to obtain a first mixed solution; adjusting the pH value of the first mixed solution to be alkaline, and adding a polyphenol solution into the first mixed solution to obtain a second mixed solution; adjusting the pH value of the second mixed solution to be acidic, and centrifuging to obtain supernate; mixing the supernate with a saccharide drying aid, and performing spray drying to obtain the combined polyphenol nanocapsule powder, the polyphenol solution is prepared by dissolving myricetin and chlorogenic acid in a solvent. The preparation method disclosed by the invention has the advantages of excellent fat reducing effect and high stability, and is suitable for preparation of polyphenol synergistic fat reducing products in industrial mass production.
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