Microcapsule, multifunctional plant fiber button based on body temperature response and pajamas

Abstract

The invention belongs to the technical field of functional clothing accessories, and particularly relates to a microcapsule, a multifunctional plant fiber button based on body temperature response and pajamas. The button comprises a button body, a plurality of storage grooves are formed in the button body, coatings are arranged on the groove walls of the storage grooves, the coatings are made of multifunctional microcapsules responding to body temperature, and heat insulation layers are arranged between the peripheral wall of the button body and the storage grooves. A plurality of air guide channels are arranged on the peripheral wall of the button body, penetrate through the heat insulation layer and are communicated with the storage groove. In the button, the multifunctional microcapsules responding to the body temperature can melt and break walls under the action of the body temperature, gaseous substances with the effects of repelling mosquitoes, helping sleep and the like are released, and therefore the effects of repelling the mosquitoes, helping sleep and the like are achieved.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of functional clothing accessories, and particularly relates to a microcapsule, a multifunctional plant fiber button based on body temperature response, and pajamas. BACKGROUND

[0002] Buttons are fasteners for connecting the two sides of a garment. Initially, buttons were only used to connect clothes, and then, with the development of the times, they have gradually developed into a representative with artistic, decorative and functional properties. Traditional sleep-aid products (such as aromatherapy, sprays) have the problems of short action time and the need for frequent use; mosquito-repelling buttons on the market mostly rely on chemical synthetic components, and long-term contact with the skin poses a safety hazard; existing functional buttons mostly focus on decoration or mechanical properties, and lack of combination with human physiological needs. Therefore, the combination of body temperature response, sleep-aid, mosquito-repelling functions and button technology can obtain a more innovative functional button, which can be applied to clothing.

[0003] In the prior art, for example, CN104890125A discloses a processing technology for mosquito-repelling buttons, which has a mosquito-repelling function, but does not have a body temperature response function. SUMMARY

[0004] To solve the problems of the prior art, the present application provides a microcapsule, a multifunctional plant fiber button based on body temperature response, and pajamas.

[0005] The technical solutions provided by the present application are as follows: A multifunctional plant fiber button based on body temperature response comprises a button body, a plurality of storage grooves are arranged in the button body, a coating layer is arranged on the groove wall of the storage groove, the material of the coating layer is a multifunctional microcapsule based on body temperature response, a heat insulation layer is arranged between the peripheral wall of the button body and each storage groove, a plurality of air guide channels are arranged on the peripheral wall of the button body, the air guide channels penetrate through the heat insulation layer and communicate with the storage grooves.

[0006] Based on the above technical solutions, the multifunctional microcapsule based on body temperature response in the button can melt and break the shell under the action of body temperature, and release gas substances with mosquito-repelling, sleep-aid and other effects, thereby achieving mosquito-repelling, sleep-aid and other effects.

[0007] Specifically, the preparation method of the multifunctional microcapsule based on body temperature response comprises the following steps: 1) preparing a core material emulsion of a mosquito-repelling core material and / or a sleep-aid core material; 2) preparing a shell material solution; 3) adding the core material emulsion dropwise into the shell material solution to perform interfacial polymerization coating; 4) low-temperature spray drying the product obtained in step 3) to obtain the body-temperature responsive multifunctional microcapsule, preferably, the particle size is 10-50 μm.

[0008] Specifically, in step 1), the mosquito-repelling core material comprises the following components in the following weight percentages: 45-55% of folium artemisiae argyi oil, 15-25% of menthol, and 25-35% of pachouli extract.

[0009] Based on the above technical solution, the gas released by the mosquito-repelling core material can play a mosquito-repelling effect.

[0010] Specifically, in step 1), the sleep-aiding core material comprises the following components in the following weight percentages: 40-60% of total jujuboside, and 60-40% of polygala volatile oil, and the sum of the two is 100%.

[0011] Based on the above technical solution, the gas released by the sleep-aiding core material can play a sleep-aiding effect.

[0012] Specifically, in step 1), an emulsifier is added to the mosquito-repelling core material and / or the sleep-aiding core material, the mass of the emulsifier is 8-12% of the total mass of the core material, high-speed shearing (2500-3500 r / min, preferably 3000 r / min, for 8-12 minutes, preferably 10 minutes) is performed to form a uniform oil phase emulsion with a particle size of ≤2 μm. Tween-80 can be used as the emulsifier.

[0013] Specifically, in step 2), N-isopropyl acrylamide monomer (NIPAM) and chitosan are dissolved in deionized water (the dissolution process can be heated, the temperature is 55-65℃, preferably 60℃), glycerol is added, and magnetic stirring (1-3 hours, preferably 2 hours) is performed for dissolution to prepare a shell material solution, wherein the concentration of N-isopropyl acrylamide monomer is 5-7%, the concentration of chitosan (a degree of deacetylation ≥90% can be used) is 2-4%, and the concentration of glycerol is 4-6%. Glycerol can play a plasticizing role.

[0014] Specifically, step 3) comprises the following steps: a) dropwise adding the core material emulsion to the shell material solution, and continuously stirring, the volume ratio of the core material emulsion to the shell material solution is 1:(3-5), preferably 1:4; b) heating to 60-70℃, preferably 65℃, adding ammonium persulfate (APS, the addition amount is 0.4-0.6wt%, preferably 0.5wt%), and reacting for 3-5h, preferably 4h, to form a microcapsule primary emulsion; c) cooling the microcapsule primary milk to room temperature, preferably 25°C, collecting the solid after centrifugation (at a speed of 3500-4500 r / min, preferably 4000 r / min, for 8-12 min, preferably 10 min), and washing the solid with deionized water, preferably 3 times, to obtain the microcapsules.

[0015] Based on steps 2) and 3): The free amino groups of chitosan can scavenge free radicals to protect easily oxidized traditional Chinese medicine ingredients such as aiye oil and menthol; its antibacterial property (destroying microbial cell membranes) prolongs the storage stability of the microcapsules; chitosan and the temperature-sensitive polymer poly-N-isopropyl acrylamide (PNIPAM) form a composite shell material, which uses the rigid molecular chain of chitosan to compensate for the mechanical performance deficiency of PNIPAM, preventing the microcapsules from breaking when drying or under pressure; Chitosan is a natural polysaccharide (chitin derivative) that gives the microcapsules degradability, reducing environmental burden and meeting the trend of green materials; By adjusting the cross-linking density of PNIPAM (poly-N-isopropyl acrylamide) in the microcapsule shell, the microcapsules can only break when the temperature rises rapidly (≥0.5°C / s), so that when they come into contact with the skin, the medicine is released quickly by the rapid temperature rise. Among the four seasons of the year, including summer, the air environment has a small temperature rise rate (usually ≈0.01°C / s), which cannot reach the response threshold of the shell material; The LCST (lower critical solution temperature) of PNIPAM is 32-34°C, and chitosan can fine-tune the LCST to 34±0.5°C through hydrogen bonding, making it more accurately match the human skin temperature (35°C); The amount of ammonium persulfate directly affects the cross-linking density of the PNIPAM chain. Low concentration: low cross-linking degree, soft shell material, fast response speed but easy to break. High concentration: high cross-linking degree, tough shell material, slow release rate but improved wash resistance; ammonium persulfate is a water-soluble initiator that is compatible with the shell material's aqueous system (chitosan + PNIPAM aqueous solution), ensuring uniformity of the reaction and avoiding local rapid polymerization that leads to uneven microcapsule sizes.

[0016] Specifically, step 4) includes the following steps: preparing a dispersion of the microcapsules in deionized water with a solid content of 15-25% (preferably 20%), and feeding the dispersion into a spray dryer to obtain dry microcapsule powder, thereby obtaining multifunctional microcapsules that respond to body temperature, with a particle size of 5-10 μm and an encapsulation efficiency of ≥85%. The temperature for spray drying is 25-40°C.

[0017] Specifically, the button body comprises a lower buckle body and an upper cover body, the cover body and the buckle body are fixedly connected together through a hot-press forming process, each storage groove is arranged on the upper end surface of the buckle body, each storage groove is a linear groove, and each storage groove is uniformly arranged around the circumference of the buckle body, and a threading hole is arranged between each storage groove for threading a suture.

[0018] Specifically, the material of the cover body is heat-conducting silica gel.

[0019] Based on the above technical solution, the human body temperature is conducive to the conduction of the body temperature response multifunctional microcapsule.

[0020] Specifically, the preparation method of the buckle body comprises the following steps: blending cotton stalk fibers (particle size ≤100 mesh) and polylactic acid (PLA), and then hot-pressing at 160-180 DEG C to form. The weight ratio of the cotton stalk fiber to the polylactic acid is (6-8): (2-4), preferably 7:3.

[0021] Based on the above technical solution, the buckle body material is environmentally friendly and biodegradable.

[0022] Specifically, the coating is formed by the body temperature response multifunctional microcapsule material in the form of electrostatic spraying, and the density is ≥200 / mm.

[0023] Specifically, the material of the heat insulation layer is aerogel.

[0024] Based on the above technical solution, the thermal conductivity of the aerogel is ≤0.02 W / (m•K), so that the temperature in the button can be prevented from being too high even at a higher temperature, for example, in summer.

[0025] Specifically, the air guide channel comprises a group of tightly connected holes, the porosity is 40-60%, and the pore size is 50-100 μm.

[0026] The application also provides a sleepwear comprising the body temperature response multifunctional plant fiber button.

[0027] Based on the above technical solution, the body temperature response multifunctional plant fiber button can continuously play the mosquito-repelling and sleep-aiding functions during the wearing and sleeping of a person.

[0028] The beneficial effects of the application are as follows: 1) Material synergy: cotton stalk fibers provide a porous carrier, PLA enhances mechanical properties, and traditional Chinese medicine microcapsules achieve functional sustained release; 2) Temperature response: the microcapsule wall material softens and breaks when it approaches the body temperature, and the effective components are released through the air guide channel; 3) Ecological compatibility: all components are biodegradable (natural degradation rate ≥80% in 28 days). Attached Figure Description

[0029] Figure 1 This is an exploded view of the multifunctional plant fiber button based on body temperature response provided by the present invention.

[0030] Appendix Figure 1 The structures represented by each label are listed below: 1. Cover; 2. Storage tank; 3. Air duct; 4. Insulation layer; 5. Insulation groove; 6. Buckle. Detailed Implementation

[0031] The principles and features of the present invention are described below. The embodiments given are only for explaining the present invention and are not intended to limit the scope of the present invention.

[0032] Unless otherwise specified, the test methods used in the embodiments are conventional methods; unless otherwise specified, the materials and reagents used are commercially available.

[0033] Supercritical CO2 extraction of Artemisia argyi oil is an existing technology and can be purchased from Chenguang Biotech.

[0034] Menthol is an existing technology and can be purchased from Chenguang Biotech.

[0035] Patchouli extract is a current technology and is available from Chenguang Biotech.

[0036] The purification of total saponins from jujube seed using macroporous resin is an existing technology and can be purchased from Chenguang Biotech.

[0037] Steam distillation is an existing technology for extracting volatile oil from Polygala tenuifolia and can be purchased from Chenguang Biotech.

[0038] Preparation of cotton stalk fiber: Cotton stalks are bleached by boiling in alkali (NaOH 5%) and then ultra-finely pulverized.

[0039] In one specific implementation, such as Figure 1 As shown, the multifunctional plant fiber button based on body temperature response includes a button body 6 at the bottom and a cover body 1 at the top.

[0040] A plurality of storage slots 2 are provided on the upper end surface of the button body 6. Each storage slot 2 is a straight slot and is evenly distributed around the circumference of the button body 6. Thread holes are provided in the area between each storage slot 2. Preferably, there are 4 storage slots 2, which can correspond to the number of thread holes of the button itself, and the thread holes of the button are provided in the area between the storage slots 2. Corresponding to the change in the number of thread holes of the button itself, for example, 3, the number of storage slots 2 can also be 3, and the thread holes of the button are provided in the area between the storage slots 2.

[0041] A coating is provided on the wall of the storage tank 2, and the coating material is a body temperature responsive multifunctional microcapsule. A heat insulation layer 4 is provided between the peripheral wall of the button body and each storage tank 2. For example, an annular heat insulation groove 5 can be provided between the peripheral wall of the button body and each storage tank 2, and the heat insulation layer 4 can be provided inside the heat insulation groove 5.

[0042] Several air-guiding channels 3 are provided on the peripheral wall of the button body. The air-guiding channels 3 penetrate the heat insulation layer 4 and connect to the storage tank 2. Through the air-guiding channels, mosquito-repellent or sleep-aiding gas substances released in the storage tank 2 can be released.

[0043] Preferably, the material of the heat insulation layer 4 is aerogel, which can prevent the multifunctional microcapsules that respond to body temperature from rupturing and releasing due to excessively high external ambient temperature.

[0044] Preferably, the cover 1 is made of thermally conductive silicone, which can directly conduct the body's heat to the storage tank 2, ensuring temperature responsiveness. Combined with the insulation layer, it responds to body temperature while avoiding responsiveness to ambient temperature.

[0045] Based on the above technical solution, the button responds to the body temperature, and the temperature-responsive multifunctional microcapsule can melt and break down under the action of body temperature, releasing gaseous substances that have mosquito-repelling and sleep-aiding effects, thereby achieving mosquito-repelling and sleep-aiding effects.

[0046] Example 1 The preparation method of thermoresponsive multifunctional microcapsules includes the following steps: 1) Preparation of core material emulsions for mosquito-repellent and sleep-aiding core materials; 2) Preparation of shell material solution; 3) Add the core material emulsion dropwise to the shell material solution to perform interfacial polymerization coating; 4) The product obtained in step 3) is subjected to low-temperature spray drying to obtain the body temperature responsive multifunctional microcapsules.

[0047] In step 1): The mosquito repellent core material comprises the following components in weight percentage: 50% Artemisia argyi oil, 20% menthol, and 30% patchouli extract. The sleep-aid core material comprises the following components in weight percentage: 40% total saponins from jujube seed and 30% volatile oil from Polygala tenuifolia. Emulsifier Tween-80 is added to the mosquito repellent core material and the sleep aid core material. The mass of the emulsifier is 10% of the total core material mass. High-speed shear emulsification is performed at 3000 r / min for 10 minutes to form a uniform oil phase emulsion.

[0048] In step 2), N-isopropyl acrylamide monomer and chitosan are dissolved in deionized water (60°C), glycerol is added, and magnetic stirring is performed for 2 hours for dissolution, to prepare a shell solution, wherein the concentration of N-isopropyl acrylamide monomer is 6%, the concentration of chitosan is 3%, and the concentration of glycerol is 5%.

[0049] Step 3) includes the following steps: a) drop the core material emulsion into the shell material solution, and continuously stir, the volume ratio of the core material emulsion to the shell material solution is 1:4; b) increase the temperature to 65°C, add ammonium persulfate, and react for 4h to form a microcapsule primary emulsion; c) cool the microcapsule primary emulsion to room temperature, collect the solid after centrifugation, and wash the solid with deionized water to obtain the microcapsule.

[0050] Step 4) includes the following steps: prepare a dispersion of the microcapsule in deionized water with a solid content of 20%, and input the dispersion into a spray dryer to obtain dry microcapsule powder, to obtain the body temperature responsive multifunctional microcapsule, and the temperature of the spray drying is 30°C.

[0051] Example 2 With reference to Example 1, the difference is that the following adjustments are made: the concentration of ammonium sulfate is adjusted to 0.4% or 0.6%, which does not affect the crosslinking density and meets the requirements of sleep aid and mosquito repellent.

[0052] Example 3 With reference to Example 1, the difference is that the following adjustments are made: the amount of chitosan is adjusted to 2.5% or 3.5%, which does not affect the body temperature responsive range of the microcapsule rupture (34°C±0.5°C).

[0053] Comparative Example 1 With reference to Example 1, the difference is that the amount of ammonium persulfate is increased to 1%, thereby adjusting the crosslinking density of the PNIPAM chain. In this case, the response rate of the microcapsule is slow, which does not meet the requirements of sleep aid and mosquito repellent.

[0054] Comparative Example 2 With reference to Example 1, the difference is that no ammonium persulfate is added. The crosslinking density of the PNIPAM chain is low, the microcapsule is more prone to rupture, the response speed is too fast, and the drug will be consumed prematurely.

[0055] Effect Example The body temperature responsive multifunctional microcapsule of Example 1 is configured into a single button, and tested.

[0056] The drug loading amount is as follows: Release amount effectiveness verification The mosquito-repelling effect meets the GB / T 13917.1-2009 standard, and the results are as follows: The sleep-aiding effect test can reach an equivalent oral dose, and the results are as follows: The above merely describes the preferred embodiments of the present application and is not intended to limit the present application, and any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A microcapsule, characterized in that, Prepared by a method comprising the following steps: 1) preparing a core material emulsion of mosquito-repelling core material and / or sleep-aiding core material; 2) preparing a shell material solution; 3) adding the core material emulsion to the shell material solution dropwise, and performing interfacial polymerization coating; 4) performing low-temperature spray drying on the product obtained in step 3) to obtain the body-temperature-responsive multifunctional microcapsules.

2. The microcapsule according to claim 1, wherein In step 1): The mosquito-repelling core material comprises the following components in the following weight percentages: 45-55% of artemisia argyi leaf oil, 15-25% of menthol, and 25-35% of pachouli extract; The sleep-aiding core material comprises the following components in the following weight percentages: 40-60% of total saponins of spina date seed, and 60-40% of volatile oil of polygala; The method for preparing the core material emulsion is to add an emulsifier to the mosquito-repelling core material and / or the sleep-aiding core material, the mass of the emulsifier being 8-12% of the total mass of the core material, and high-speed shearing emulsification is performed to form a uniform oil phase emulsion.

3. The microcapsule of claim 1, wherein In step 2), the method for preparing the shell material solution is to dissolve N-isopropyl acrylamide monomers and chitosan in deionized water, and add glycerol, and then perform magnetic stirring and dissolution to prepare the shell material solution, wherein the concentration of the N-isopropyl acrylamide monomers in the shell material solution is 5-7%, the concentration of the chitosan is 2-4%, and the concentration of the glycerol is 4-6%.

4. The microcapsule of claim 1, wherein Step 3) specifically comprises the following steps: a) adding the core material emulsion to the shell material solution dropwise, and continuously stirring, the volume ratio of the core material emulsion to the shell material solution being 1:(3-5); b) increasing the temperature to 60-70℃, adding 0.4-0.6wt% of ammonium persulfate to the mixed solution obtained in step a), and performing interfacial polymerization coating for 3-5h to form a microcapsule primary emulsion; c) cooling the microcapsule primary emulsion to room temperature, collecting the solid after centrifugation, and washing the solid with deionized water to obtain the microcapsules.

5. The microcapsule of claim 1, wherein Step 4) specifically comprises the following steps: preparing a dispersion of the microcapsules in deionized water with a solid content of 15-25%, and inputting the dispersion into a spray dryer to obtain dry microcapsule powder, i.e. the body-temperature-responsive multifunctional microcapsules, the temperature of the spray drying being 25-40℃.

6. A multifunctional plant fiber button based on a body temperature response, characterized by, Comprise: A button body is provided with a plurality of storage grooves (2), a coating is arranged on the groove wall of the storage groove (2), the material of the coating is the body-temperature-responsive multifunctional microcapsules according to any one of claims 1 to 5, a heat insulation layer (4) is arranged between the circumferential wall of the button body and each of the storage grooves (2), a plurality of air guide channels (3) are arranged on the circumferential wall of the button body, the air guide channels (3) penetrate through the heat insulation layer (4) and communicate with the storage grooves (2).

7. The multifunctional plant fiber button based on a body temperature response according to claim 6, characterized by: The button body comprises a lower buckle body (6) and an upper cover body (1), the cover body (1) and the buckle body (6) are fixedly connected together through a hot press forming process, each of the storage grooves (2) is arranged on the upper end surface of the buckle body (6), each of the storage grooves (2) is a linear groove, each of the storage grooves (2) is uniformly arranged around the circumference of the buckle body (6), and a threading hole is arranged in the region between each of the storage grooves (2). 8.The multifunctional plant fiber button based on body temperature response according to claim 7, characterized in that: the material of the cover (1) is heat-conducting silica gel; the preparation method of the button body (6) comprises the following steps: cotton stalk fibers and polylactic acid are blended, and then formed by hot pressing at 160-180 ℃, and the weight ratio of the cotton stalk fibers and the polylactic acid is (6-8):(2-4). 9.The multifunctional plant fiber button based on body temperature response according to claim 6, characterized in that: the coating is formed by electrostatic spraying of the multifunctional microcapsule material based on body temperature response; the material of the thermal insulation layer (4) is aerogel.

10. A nightwear characterized by: The multifunctional plant fiber button based on body temperature response according to any one of claims 6 to 9.

Images