Fluorescent probe for detecting metal mercury ions as well as preparation method and application of fluorescent probe

By designing the fluorescent probe P-Hg, the problems of low sensitivity, insufficient anti-interference ability and poor stability of Hg2+ detection in the environment are solved, realizing rapid response and high selectivity of Hg2+ detection, which is suitable for the detection of various environmental samples.

CN120904102AInactive Publication Date: 2025-11-07临沂科技职业学院
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Patent Information

Application Number
CN202510963061.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-14
Publication Date
2025-11-07
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing Hg2+ detection methods suffer from low sensitivity, insufficient resistance to matrix interference, poor stability, and poor field applicability, making it difficult to achieve high sensitivity, rapid response, and high selectivity for Hg2+ detection.

Method used

A fluorescent probe, P-Hg, with the molecular formula C21H20O5N2S, was designed. It reacts rapidly with Hg2+ to generate strong green fluorescence, exhibiting high sensitivity and selectivity. It can detect Hg2+ in real water samples, crop soil, plant roots, and isolated live cells.

Benefits of technology

It achieves rapid response (<10s), nanomolar detection limit (1.0nM) and excellent anti-interference ability for Hg2+, and is suitable for detection in real water samples, crop soil, plant roots and in vitro live cells, providing a new tool for environmental risk assessment and Hg2+-related disease research.

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Abstract

The invention discloses a fluorescent probe for detecting metal mercury ions and a preparation method and application thereof, the molecular formula of the probe is C21H20O5N2S, and the structural formula is shown in the specification. The invention designs a fluorescent probe for detecting metal mercury ions (Hg < 2 + >) aiming at environmental Hg < 2 + > monitoring requirements. The probe can rapidly react with Hg < 2 + > (response time is 1t, 10 s), and has nanomole-level detection sensitivity (detection limit is 1.0 nM) and excellent anti-interference capability. The method is applied to detection of mercury ions (Hg < 2 + >) in real water samples, crop soil, plant root systems and in-vitro living cells. And a novel tool is provided for providing intermediate information for pathological research of Hg < 2 + > related diseases and evaluating environmental toxicity.
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