Anti-dandruff and oil-control hair composition and application thereof

Abstract

The invention relates to a hair composition for removing dandruff and controlling oil and application thereof. The hair composition comprises piroctone olamine salt, polyquaternium-10, salicylic acid, a lactobacillus fermentation product and a plant extract. According to the invention, various active components are compounded and have a synergistic effect, so that the scalp environment can be adjusted from multiple dimensions, and the long-acting cleaning, oil control and dandruff removal effects are achieved.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and in particular to a hair composition for dandruff control and oil control, and its application. Background Technology

[0002] Shampoo is a necessity in people's daily lives. With the development of technology and the improvement of people's living standards, people's requirements for shampoo are no longer limited to just cleaning hair. They also require it to have other functions, such as dandruff removal and itch relief, repair of damaged hair, and oil control.

[0003] Dandruff is a product of the metabolism of epidermal cells on the scalp, a process of keratinization of the scalp. The stratum corneum is particularly prone to shedding in dry conditions, resulting in excessive dandruff. Oily scalps, due to their higher sebum content, provide better moisturization and produce less dandruff. However, the excess sebum accumulates on the hair, making it very greasy and unclean, severely impacting its appearance.

[0004] CN115154390A discloses an anti-dandruff and oil-controlling shampoo, comprising the following components: solvent, surfactant, moisturizer, hair conditioning agent, preservative, fragrance, pearlescent agent, thickener, suspending agent, pH adjuster, chelating agent, and anti-dandruff agent. The hair conditioning agent includes at least Cnidium monnieri extract, Lactobacillus / soybean fermentation product filtrate, and Inulin root juice.

[0005] CN106236659A discloses an anti-dandruff and oil-controlling shampoo, which is prepared by conventional mixing of the following raw materials: sodium lauryl ether sulfate, Sophora flavescens root extract, Platycladus orientalis leaf extract, ginger extract, cocamide, ethylene glycol distearate, cetearyl alcohol, cocamidopropyl betaine, etc.

[0006] However, the dandruff control and oil control effects of existing products need to be improved, so it is necessary to develop more effective dandruff control and oil control shampoos. Summary of the Invention

[0007] To address the aforementioned technical problems, this invention provides a dandruff-reducing and oil-controlling hair composition and its application. This invention, through the compounding of multiple active ingredients, achieves a synergistic effect, regulating the scalp environment from multiple dimensions and providing long-lasting cleansing, oil control, and dandruff removal.

[0008] To achieve this objective, the present invention adopts the following technical solution:

[0009] In a first aspect, the present invention provides a hair composition for dandruff control and oil control, the hair composition comprising piroctone olamine salt, polyquaternium-10, salicylic acid, lactobacillus fermentation product and plant extract.

[0010] In this invention, piroctone olamine salt can inhibit Malassezia, reduce the number of fungi, help restore the balance of scalp flora, indirectly regulate sebum secretion, improve oily scalp, and provide long-lasting dandruff removal. Polyquaternium-10 can adsorb oil and dirt on the surface of the scalp and hair, achieving a cleaning effect, while also eliminating bacteria, viruses, and fungi on the scalp, thus protecting scalp health and preventing dandruff. Salicylic acid can dissolve the scalp stratum corneum, loosen the oil and dirt clogging hair follicles, reduce dandruff production and relieve itching, and can also penetrate deep into the hair follicles to reduce the amount of oil secreted by the sebaceous glands. Lactobacillus fermentation products can balance the scalp flora, reduce the growth of harmful bacteria such as Malassezia, maintain a healthy scalp environment, and thus relieve dandruff and itching problems. Based on the above components, this invention combines natural plant extracts, and the various components work synergistically to regulate the scalp environment from multiple dimensions, providing long-lasting cleansing, oil control, and dandruff removal effects.

[0011] Preferably, the hair composition comprises, by weight parts, 18-45 parts of piroctone ethanolamine salt, 18-45 parts of polyquaternium-10, 0.0006-0.0015 parts of salicylic acid, 0.0015-0.004 parts of lactobacillus fermentation product and 0.0015-0.0045 parts of plant extract.

[0012] In this invention, the amount of piroctone ethanolamine salt can be, for example, 18 parts, 20 parts, 25 parts, 30 parts, 35 parts, 40 parts, 45 parts, etc.; the amount of polyquaternium-10 can be, for example, 18 parts, 20 parts, 25 parts, 30 parts, 35 parts, 40 parts, 45 parts, etc.; the amount of salicylic acid can be, for example, 0.0006 parts, 0.0009 parts, 0.0012 parts, 0.0015 parts, etc.; the amount of lactobacillus fermentation product can be, for example, 0.0015 parts, 0.002 parts, 0.003 parts, 0.004 parts, etc.; and the amount of plant extract can be, for example, 0.0015 parts, 0.0025 parts, 0.0035 parts, 0.0045 parts, etc.

[0013] Preferably, the plant extract includes any one or a combination of at least two of the following: salvia miltiorrhiza extract, camellia seed extract, or white willow bark extract, and more preferably a combination of salvia miltiorrhiza extract, camellia seed extract, and white willow bark extract.

[0014] In this invention, tanshinone extract inhibits inflammatory factors, reducing redness and itching of the scalp caused by seborrheic dermatitis, folliculitis, etc., helping to repair the damaged scalp barrier. It also has a certain inhibitory effect on 5α-reductase, reducing excessive sebum secretion, alleviating the stickiness of oily scalp, and lowering the risk of clogged hair follicles. Camellia seed extract has antibacterial and moisturizing effects, preventing scalp itching, relieving itching, and removing dandruff. White willow bark extract dissolves excess oil and keratin plugs, gently controlling oil without drying out the scalp, and does not damage the scalp barrier. It works synergistically with other components to achieve a dandruff-removing effect.

[0015] In this invention, when a combination of plant extracts, namely, salvia miltiorrhiza extract, camellia seed extract, and white willow bark extract, is used, the three components can work synergistically to enhance the dandruff-removing and oil-controlling effects of the composition.

[0016] In this invention, the plant extract can be a commercially available product or it can be prepared in-house. In-house preparation can be achieved using conventional extraction methods in the art, such as extraction with an organic solvent under heat, followed by concentration and drying of the supernatant.

[0017] Preferably, the mass ratio of the plant extracts, including salvia miltiorrhiza extract, camellia seed extract, and white willow bark extract, is 1:(0.8-1.5):(0.2-1).

[0018] The values ​​mentioned above (0.8-1.5) can be, for example, 0.8, 1, 1.2, 1.4, 1.5, etc.; (0.2-1) can be, for example, 0.2, 0.4, 0.6, 0.8, 1, etc.

[0019] In a second aspect, the present invention provides the application of the dandruff-reducing and oil-controlling hair composition according to the first aspect in shampoo and hair care products.

[0020] Thirdly, the present invention provides a dandruff-reducing and oil-controlling shampoo, the shampoo comprising active substances, surfactants, moisturizers, pH adjusters, chelating agents, and water; the active substances comprising the dandruff-reducing and oil-controlling hair composition described in the first aspect.

[0021] Preferably, the shampoo comprises, by weight percentage, 0.001-5% (e.g., 0.001%, 0.01%, 0.1%, 0.5%, 1%, 5%, etc.) of active ingredients, 5-30% (e.g., 5%, 10%, 15%, 20%, 25%, 30%, etc.) of surfactants, 0.01-5% (e.g., 0.01%, 0.1%, 0.5%, 1%, 2%, 5%, etc.) of moisturizers, 0.01-1% (e.g., 0.01%, 0.1%, 0.2%, 0.5%, 1%, etc.) of pH adjusters, 0.01-1% (e.g., 0.01%, 0.1%, 0.2%, 0.5%, 1%, etc.) of chelating agents, and 60-95% (e.g., 60%, 70%, 80%, 90%, 95%, etc.) of water.

[0022] Preferably, the surfactant comprises any one or a combination of at least two of the following: sodium lauryl ether sulfate, cocamidopropyl betaine, cocamidopropylamine (MEA), sodium lauroyl sarcosinate, octyl / decyl glucoside, PEG-7 glyceryl cocoate, sodium isostearyl lactylate, isostearic acid, sodium lauryl glucocarboxylate, or lauryl glucoside.

[0023] Preferably, the moisturizer comprises any one or a combination of at least two of glycerin, butylene glycol, 1,2-hexanediol, 1,2-pentanediol, isopropanol, or sodium hyaluronate.

[0024] Preferably, the pH adjuster comprises potassium hydroxide and / or citric acid.

[0025] Preferably, the chelating agent comprises disodium EDTA.

[0026] Fourthly, the present invention provides a method for preparing a dandruff-reducing and oil-controlling shampoo according to the third aspect, the method comprising: mixing and dissolving the raw materials to obtain the shampoo.

[0027] Compared with the prior art, the present invention has at least the following beneficial effects:

[0028] The hair-care composition provided by this invention has a synergistic effect among the components of piroctone ethanolamine salt, polyquaternium-10, salicylic acid, lactobacillus fermentation product and plant extract, which can give the composition a long-lasting synergistic effect of dandruff removal and oil control from multiple dimensions. Detailed Implementation

[0029] To facilitate understanding of the present invention, the following embodiments are provided. Those skilled in the art should understand that these embodiments are merely illustrative and should not be construed as limiting the scope of the invention.

[0030] The polyquaternium salt-10 used in the following examples is commercially known as UCARE. TM Polymer JR-400P, manufactured by Dow Chemical (Shanghai) Co., Ltd.; the commercial name of the Lactobacillus fermentation product is... L19 is manufactured by Symrise Fragrance & Flavor (Nantong) Co., Ltd.; Salvia miltiorrhiza extract is manufactured by Shaanxi Muling Biotechnology Co., Ltd.; Camellia oleifera seed extract is manufactured by Lanzhou Waterles Biotechnology Co., Ltd.; and the white willow bark extract is manufactured by Xi'an Lvtian Biotechnology Co., Ltd.

[0031] The weight percentages of the raw materials mentioned above are based on the actual content of active ingredients in commercially available raw materials. Commercially available raw materials may also selectively contain any one or a combination of at least two of the following: solvents, fillers, diluents, stabilizers, pH adjusters, antibacterial agents, antioxidants, or impurities within permissible limits.

[0032] Example 1

[0033] This embodiment provides a hair composition for dandruff control and oil control, comprising, by weight parts: 30 parts of piroctone olamine salt, 30 parts of polyquaternium-10, 0.001 parts of salicylic acid, 0.0025 parts of lactobacillus fermentation product, and 0.003 parts of plant extracts (tanshinone extract, camellia seed extract, and white willow bark extract in a weight ratio of 1:1:0.5).

[0034] Example 2

[0035] This embodiment provides a hair composition for dandruff control and oil control, comprising, by weight parts, 18 parts of piroctone olamine salt, 45 parts of polyquaternium-10, 0.0006 parts of salicylic acid, 0.004 parts of lactobacillus fermentation product, and 0.0015 parts of plant extracts (in a weight ratio of 1:0.8:1), namely, tanshinone extract, camellia seed extract, and white willow bark extract.

[0036] Example 3

[0037] This embodiment provides a hair composition for dandruff control and oil control, comprising, by weight parts: 45 parts of piroctone olamine salt, 18 parts of polyquaternium-10, 0.0015 parts of salicylic acid, 0.001 parts of lactobacillus fermentation product, and 0.0045 parts of plant extracts (tanshinone extract, camellia seed extract, and white willow bark extract in a weight ratio of 1:1.5:0.2).

[0038] Example 4

[0039] This embodiment provides a hair composition for dandruff control and oil control. The only difference between this embodiment and Example 1 is that the plant extract does not contain tanshinone extract. The amount of tanshinone extract is distributed according to the ratio of camellia seed extract and white willow bark extract, while keeping the total amount of plant extract unchanged. Other aspects are the same as in Example 1.

[0040] Example 5

[0041] This embodiment provides a hair composition for dandruff control and oil control. The only difference between this embodiment and Example 1 is that the plant extract does not contain camellia seed extract. The amount of camellia seed extract is distributed according to the ratio of salvia miltiorrhiza extract and white willow bark extract, while keeping the total amount of plant extract unchanged. Other aspects are the same as in Example 1.

[0042] Example 6

[0043] This embodiment provides a hair composition for dandruff control and oil control. The only difference between this embodiment and Example 1 is that the plant extract does not contain white willow bark extract. The amount of white willow bark extract is distributed according to the ratio of salvia miltiorrhiza extract and camellia seed extract, while keeping the total amount of plant extract unchanged. Other aspects are the same as in Example 1.

[0044] Comparative Example 1

[0045] This comparative example provides a hair composition for dandruff control and oil control. The only difference between this and Example 1 is that the hair composition does not contain piroctone ethanolamine salt, and its dosage is allocated according to the proportion of the remaining components. Other aspects are the same as in Example 1.

[0046] Comparative Example 2

[0047] This comparative example provides a hair composition for dandruff control and oil control. The only difference between this and Example 1 is that the hair composition does not contain polyquaternium-10, and its dosage is allocated according to the proportion of the remaining components. Other aspects are the same as in Example 1.

[0048] Comparative Example 3

[0049] This comparative example provides a hair composition for dandruff control and oil control. The only difference between this and Example 1 is that the hair composition does not contain salicylic acid, and its dosage is allocated according to the proportion of the remaining components. Other aspects are the same as in Example 1.

[0050] Comparative Example 4

[0051] This comparative example provides a hair composition for dandruff control and oil control. The only difference between this and Example 1 is that the hair composition does not contain lactobacillus fermentation products, and its dosage is allocated according to the proportion of the remaining components. Other aspects are the same as in Example 1.

[0052] Comparative Example 5

[0053] This comparative example provides a hair composition for dandruff control and oil control. The only difference between this and Example 1 is that the hair composition does not contain plant extracts, and its dosage is allocated according to the proportion of the remaining components. Other aspects are the same as in Example 1.

[0054] Application Example 1

[0055] This application example provides an anti-dandruff and oil-controlling shampoo, comprising the following components:

[0056]

[0057] The method for preparing the shampoo includes:

[0058] The components are mixed and dissolved, and then defoamed under vacuum to obtain the shampoo.

[0059] Application Example 2-6

[0060] Application Examples 2-6 each provide a dandruff-removing and oil-controlling shampoo. The only difference between them and Application Example 1 is that the hair composition provided in Example 1 is replaced in equal amounts with the hair composition provided in Examples 2-6. Other aspects are the same as in Example 1.

[0061] Compare and contrast examples 1-5

[0062] Comparative Application Examples 1-5 each provide a dandruff-reducing and oil-controlling shampoo. The only difference between them and Application Example 1 is that the hair composition provided in Example 1 is replaced in equal amounts with the hair composition provided in Comparative Examples 1-5. Otherwise, they are the same as in Example 1.

[0063] Test case

[0064] Cleaning and dandruff removal test

[0065] 110 participants aged 20-46 years were recruited to conduct dandruff tests using the shampoos provided in Examples 1-6 and 1-5, and to conduct self-assessments. Participants were randomly assigned to groups of 10, and participants were not allowed to wash their hair within 72 ± 4 hours before the visit.

[0066] (1) Test Items

[0067] ① Dandruff grade assessment: Laboratory experts assess and score the dandruff grade of the subjects' scalps before sample use and at each follow-up visit. The dandruff grade assessment includes visual assessment and image assessment, and the mean of the two is calculated as the dandruff grade.

[0068] Visual assessment: During each visit, laboratory experts will assess the level of dandruff on-site and record the rating.

[0069] Image assessment: Photos of the scalp and dandruff are taken at each visit. After all visits are completed, laboratory experts assess the dandruff level of the photos and record the rating.

[0070] The scoring criteria for dandruff levels are shown in the table below.

[0071] Classification meaning 0 No dandruff 1 Occasionally, fine, slight peeling may be observed. 2 Visible dandruff on scalp and hair 3 There is a lot of visible dandruff on the scalp and hair. 4 A small amount of large flakes or a large amount of small flakes on the scalp and hair 5 Large amounts of dandruff on the scalp and hair

[0072] ② Subject self-assessment

[0073] A questionnaire survey was conducted 15 minutes after using the sample, 14 days after using the sample, 28 days after using the sample, and 7 days after discontinuing the use of the sample to evaluate the user's experience after using the sample. The evaluation indicators are shown in the table below.

[0074]

[0075] Questions 1-6 and 9-10: Use a 5-point scale, where 1 point represents strongly disagreement, 2 points represent disagreement, 3 points represent somewhat agreement, 4 points represent agreement, and 5 points represent strongly agreement. Count the number of people who scored 3 or higher as valid participants. The consensus rate is calculated as follows: Consensus Rate = [(Number of people who scored 3 + Number of people who scored 4 + Number of people who scored 5) / Total Number of People] × 100%.

[0076] Questions 7-8: Choose "agree" or "disagree". Calculate the percentage of people who agree and disagree. The consensus rate = (number of people who agree / total number of people) × 100%.

[0077] (2) Test steps:

[0078] Before using the sample (D0): ① The subject sat quietly for 30 minutes in a laboratory with a temperature of 21±1℃ and a humidity of 50±10%RH; ② The dandruff level was assessed by combining visual and image evaluation; ③ The laboratory technician instructed the subject on how to use the sample on site. The method of sample use is as follows: after wetting the hair, take an appropriate amount of sample in the palm of your hand, lather it up and apply it to the hair, gently massage the hair and scalp with your fingertips, and finally rinse it with clean water.

[0079] 15 minutes after sample use (D0-15min): ① After drying their hair, the subjects sat quietly for 15 minutes in a laboratory with a temperature of 21±1℃ and a humidity of 50±10%RH; ② Dandruff level was assessed by combining visual and image assessments; ③ The subjects completed a self-assessment questionnaire.

[0080] 14 days after sample use (D14) / 28 days after sample use (D28) / 7 days after sample discontinuation (D35): ① Dandruff level assessment was performed by combining visual and image assessments; ② Subjects completed a self-assessment questionnaire.

[0081] (3) Test Results

[0082] The dandruff scores of the shampoos provided in Application Examples 1-6 and Comparative Application Examples 1-5 are shown in Table 1 (the scores are averages). The self-assessment results of the subjects are shown in Table 2.

[0083] Table 1

[0084] Grouping D0 D0-15min D14 D28 D35 Application Example 1 3.2 1.6 1.5 1.6 1.6 Application Example 2 3.2 1.5 1.4 1.6 1.5 Application Example 3 3.1 1.6 1.3 1.5 1.5 Application Example 4 3.0 1.8 1.8 1.7 1.8 Application Example 5 3.1 1.7 1.7 1.8 1.7 Application Example 6 3.0 1.7 1.7 1.7 1.7 Comparative Application Example 1 3.0 2.5 2.6 2.5 2.5 Comparative Application Example 2 3.1 2.6 2.7 2.6 2.5 Comparative Application Example 3 3.1 2.7 2.7 2.6 2.7 Comparative Application Example 4 3.2 2.7 2.8 2.7 2.7 Comparative Application Example 5 3.2 2.8 2.8 2.7 2.7

[0085] Table 2

[0086]

[0087]

[0088]

[0089] Combining Table 1 and Table 2, we can see that:

[0090] As can be seen from Application Examples 1-6, the components of the hair-care composition provided by this invention—pyrrolidone ethanolamine salt, polyquaternium-10, salicylic acid, lactobacillus fermentation product, and plant extracts—exhibit a synergistic effect, providing a long-lasting cleansing and dandruff-removing synergistic effect from multiple dimensions. Specifically, after 15 minutes of single use, it has a dandruff-cleansing effect; after 14 days, 28 days of use, and a 7-day discontinuation period, it has a dandruff-removing effect.

[0091] A comparison of Application Examples 1 and 4-6 shows that when the plant extracts in the hair care composition provided by the present invention are a compound combination of Salvia miltiorrhiza extract, Camellia oleifera seed extract and white willow bark extract, the dandruff-removing effect is further improved.

[0092] A comparison of Application Example 1 and Comparative Application Examples 1-5 shows that when any one of the components is missing from the hair composition provided by the present invention, the dandruff-removing effect decreases and the subject's acceptance rate drops.

[0093] Test Example 2

[0094] Oil control test: 5α-reductase inhibition rate test

[0095] Test method:

[0096] Positive control group: Dissolve 10 mg dutasteride in 1 mL of ethanol solution to obtain dutasteride stock solution with a concentration of 10 mg / mL; dilute the dutasteride stock solution with ethanol at a ratio of 1:1000 to 10 μg / mL to obtain the positive control working solution.

[0097] Add the reagents and incubate them sequentially according to the steps in the table below, with three parallel samples per group.

[0098]

[0099] Inhibition rate (%) = (1 - change in absorbance of sample group over 1 hour / change in absorbance of blank group over 1 hour) × 100%. The shampoos provided in Application Examples 1-6 and Comparative Application Examples 1-5 were mixed and dissolved with ethanol to prepare samples of 0.25 mg / mL for testing. The results are shown in Table 3.

[0100] Table 3

[0101] Grouping Average inhibition rate (%) Application Example 1 55.80 Application Example 2 54.81 Application Example 3 52.69 Application Example 4 50.36 Application Example 5 51.54 Application Example 6 48.67 Comparative Application Example 1 27.35 Comparative Application Example 2 26.47 Comparative Application Example 3 23.58 Comparative Application Example 4 21.94 Comparative Application Example 5 20.35

[0102] As can be seen from Table 3, the composition provided by the present invention, through the reasonable combination of its components, has both dandruff removal and excellent oil control effects. When any one of the components is missing, the oil control effect decreases.

[0103] The applicant declares that the above description is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Those skilled in the art should understand that any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention fall within the protection and disclosure scope of the present invention.

Claims

1. A hair composition for dandruff control and oil control, characterized in that, The hair composition comprises piroctone ethanolamine salt, polyquaternium-10, salicylic acid, lactobacillus fermentation product, and plant extracts.

2. The hair-applied composition according to claim 1, characterized in that, The hair-applied composition comprises, by weight parts, 18-45 parts of piroctone ethanolamine salt, 18-45 parts of polyquaternium-10, 0.0006-0.0015 parts of salicylic acid, 0.0015-0.004 parts of lactobacillus fermentation product, and 0.0015-0.0045 parts of plant extract.

3. The hair-applied composition according to claim 1 or 2, characterized in that, The plant extract includes any one or a combination of at least two of the following: Salvia miltiorrhiza extract, Camellia oleifera seed extract, or Salix babylonica bark extract, preferably a combination of Salvia miltiorrhiza extract, Camellia oleifera seed extract, and Salix babylonica bark extract.

4. The hair-applied composition according to claim 3, characterized in that, The mass ratio of the plant extracts, including Salvia miltiorrhiza extract, Camellia oleifera seed extract, and Salix babylonica bark extract, is 1:(0.8-1.5):(0.2-1).

5. The use of a dandruff-reducing and oil-controlling hair composition according to any one of claims 1-4 in shampoo and hair care products.

6. A dandruff-removing and oil-controlling shampoo, characterized in that, The shampoo comprises active substances, surfactants, moisturizers, pH adjusters, chelating agents, and water; the active substances include the dandruff-reducing and oil-controlling hair composition according to any one of claims 1-4.

7. The shampoo according to claim 6, characterized in that, The shampoo comprises, by weight percentage, 0.001-5% active ingredients, 5-30% surfactants, 0.01-5% moisturizers, 0.01-1% pH adjusters, 0.01-1% chelating agents, and 60-95% water.

8. The shampoo according to claim 6 or 7, characterized in that, The surfactant includes any one or a combination of at least two of the following: sodium lauryl ether sulfate, cocamidopropyl betaine, cocamidopropyl MEA, sodium lauroyl sarcosinate, octyl / decyl glucoside, PEG-7 glyceryl cocoate, sodium isostearyl lactylate, isostearic acid, sodium lauryl glucocarboxylate, or lauryl glucoside. Preferably, the moisturizer comprises any one or a combination of at least two of glycerin, butylene glycol, 1,2-hexanediol, 1,2-pentanediol, isopropanol, or sodium hyaluronate.

9. The shampoo according to any one of claims 6-8, characterized in that, The pH adjuster includes potassium hydroxide and / or citric acid; Preferably, the chelating agent comprises disodium EDTA.

10. A method for preparing an anti-dandruff and oil-controlling shampoo according to any one of claims 6-9, characterized in that, The preparation method includes: mixing and dissolving the raw materials to obtain the shampoo.

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