Lightweight bone loss tester based on immune marker

Abstract

The invention discloses a lightweight bone loss tester based on an immune marker, and relates to the technical field of medical instruments, the lightweight bone loss tester comprises a shell, the top of the shell is provided with a display screen, and the shell is internally provided with a sample introduction mechanism for controlling a to-be-detected sample to enter and exit from the shell. Firstly, a sample to be detected is fed into the shell under the action of the sample injection mechanism, then under the action of the pipetting mechanism, the pipetting mechanism is used for sucking the sample to be detected and putting the sample into the detection mechanism, and under the action of the detection mechanism, immune markers contained in the sample to be detected are detected; the bone loss risk is evaluated by combining parameters such as the age and the gender of a patient, and under the condition that the detection effect is ensured, the inspection operation is simplified, the equipment structure is simplified, and the purpose of light weight is achieved, so that the purposes of reducing the cost, shortening the waiting time and meeting the requirements of short-term and dynamic monitoring of some patients are achieved.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a lightweight bone loss detection device based on immune markers. Background Technology

[0002] Bone loss refers to the gradual decrease in bone density and the destruction of bone tissue microstructure, leading to brittle bones and increased susceptibility to fractures. It is commonly seen in osteoporosis. The main causes include aging, hormonal changes, malnutrition, and lack of exercise. Prevention and treatment require a comprehensive approach, including dietary adjustments, calcium and vitamin D supplementation, appropriate exercise, and medication.

[0003] Currently, commonly used methods for detecting bone loss include bone mineral density testing (such as DXA), bone metabolic marker detection, imaging examinations (such as X-ray, CT, and MRI), and other methods (such as quantitative ultrasound). Among these, the detection of bone metabolic markers is mainly performed using electrochemiluminescence immunoassay analyzers, enzyme-linked immunosorbent assay (ELISA) equipment, fully automated biochemical analyzers, and related auxiliary equipment. These devices are typically large, suitable for hospital use, but due to their cumbersome procedures, high costs, and long waiting times, they cannot meet the needs of short-term, dynamic monitoring. This makes it difficult for patients with fractures or other reasons who cannot easily travel to the hospital for related examinations to monitor changes in their bone loss data. Therefore, this application proposes a lightweight bone loss detection device based on immunomarkers to solve the above problems. Summary of the Invention

[0004] This invention provides a lightweight bone loss detection device based on immune markers to solve the problems mentioned in the background art.

[0005] To solve the above-mentioned technical problems, the technical solution adopted by the present invention is as follows:

[0006] A lightweight bone loss detection instrument based on immune markers includes a housing, a display screen mounted on the top of the housing, and a sample introduction mechanism inside the housing for controlling the entry and exit of the sample to be tested.

[0007] The testing facility is used to detect the immunomarkers contained in the sample to be tested. The shell is equipped with a pipetting mechanism for drawing up the sample and dripping it into the testing facility.

[0008] The data processing unit is used to process and analyze the detection signals.

[0009] It also includes a power supply mechanism and a signal transmission module, used for power supply, data transmission and signal transmission.

[0010] A further improvement of the technical solution of the present invention is that: the detection mechanism includes a detection box, a detection strip is movably connected inside the detection box, a second inclined connecting block is movably connected to one side of the detection box, a biosensor is fixedly connected to the second inclined connecting block, a second locking block is fixedly connected to the bottom of the second inclined connecting block, and the second locking block can slide along a third locking groove opened inside the outer shell.

[0011] The detection box moves along slot three to the outside of the outer shell. The user puts the detection strip into the detection box, and the detection box moves back along slot three to the inside of the outer shell to detect the sample through the biosensor.

[0012] A further improvement of the technical solution of the present invention is that: when the detection strip is an antibody-coated LFIA strip, the biosensor is a photoelectric sensor used to detect the color and fluorescence changes of the detection strip, and uses gold nanoparticles or fluorescent markers to detect bone turnover markers. The detection results are transmitted to the data processing unit through a signal transmission module.

[0013] A further improvement of the technical solution of the present invention is that: when the detection strip is an electrode chip with surface-fixed antibodies, the biosensor is an electrochemical analyzer used to monitor the changes in current or resistance caused by immune markers in the sample being tested, and the monitoring results are transmitted to the data processing unit through a signal transmission module.

[0014] A further improvement of the technical solution of the present invention is that the immune markers in the shell include one or more of the following: bone formation: osteocalcin, N-terminal procollagen peptide; bone resorption: C-terminal peptide, deoxypyridinium liner; and inflammatory factors: IL-6, TNF-α.

[0015] A further improvement of the technical solution of the present invention is that: the sample injection mechanism includes a base, a test tube containing the sample to be tested is movably connected in the base, a slanted connecting block is movably connected to one side of the base, a slide is movably connected to the bottom of the slanted connecting block, a locking block is fixedly connected to the bottom of the slanted connecting block, a locking groove is provided on the slide, and the locking block can slide along the locking groove.

[0016] The base moves along the second slot to the outside of the shell. The user places the test tube containing the sample to be tested into the base, and the base moves back to the inside of the shell along the second slot. A limiting groove is provided on the slide, and a sliding rod is movably connected to the inner wall of the limiting groove. The slide can move the test tube laterally along the sliding rod, which facilitates subsequent operations on the sample to be tested.

[0017] A further improvement of the technical solution of the present invention is that: a blood collection port is provided on one side of the outer shell, a needle puncture hole is provided at the bottom of the inner cavity of the blood collection port, the blood collection port is connected to the inner cavity of the outer shell through the needle puncture hole, a blood collection needle is movably connected to the bottom of the needle puncture hole, a bottom sleeve is movably connected to the bottom of the blood collection needle, a telescopic rod is fixedly connected to the bottom of the inner cavity of the bottom sleeve, the output end of the telescopic rod is movably connected to the bottom of the blood collection needle, and a driving device is movably connected to one end of the bottom sleeve through a shaft, and the driving device is fixedly connected to the inner wall of the outer shell.

[0018] The drive unit rotates the bottom sleeve to the outside of the outer shell. The user puts the blood collection needle into the bottom sleeve, and then the drive unit rotates the bottom sleeve back to the inside of the outer shell, aligning it with the puncture hole. The user places the fingertip of the finger to be blooded down into the blood collection port. The telescopic rod pushes the blood collection needle upward to complete the puncture treatment of the fingertip. Then the drive unit moves the bottom sleeve to the outside of the outer shell, and the blood flowing from the fingertip will fall into the test tube.

[0019] A further improvement of the technical solution of the present invention is that: a compression airbag is fixedly connected to the top of the inner cavity of the blood collection port, and a micro air pump is provided inside the outer shell to operate the inflation and deflation of the compression airbag. When the driving device moves the blood collection needle after the needle is inserted to the outside of the outer shell, the micro air pump inflates the compression airbag and expands, squeezing the finger placed in the blood collection port, which facilitates the collection of fingertip blood.

[0020] A further improvement of the technical solution of the present invention is that: multiple movable grooves are provided on the inner wall of the bottom sleeve, and a retaining ball is movably connected to the inner wall of each movable groove. An elastic block is fixedly connected to the inner wall of the movable groove. Multiple retaining slots are correspondingly provided on the outer surface of the blood collection needle. The retaining ball and the retaining slot form a retaining action, so that the blood collection needle can be placed in the bottom sleeve and remain stable.

[0021] A further improvement of the technical solution of the present invention is that the blood collection needle, test tube and test strip are all disposable consumables, and need to be replaced after each test.

[0022] Due to the adoption of the above technical solution, the technical progress achieved by this invention compared to the prior art is as follows:

[0023] 1. This invention provides a lightweight bone loss detection instrument based on immune markers. First, the sample to be tested is delivered into the interior of the casing through a sample introduction mechanism. Then, a pipetting mechanism (a prior art technology) is used to aspirate the sample and place it into the detection mechanism. Under the action of the detection mechanism, the immune markers contained in the sample are detected, and the detection data is transmitted to a data processing mechanism. The bone loss risk is assessed in conjunction with parameters such as the patient's age and gender. While ensuring the detection effect, the examination operation is simplified and the equipment structure is streamlined, achieving the goal of lightweight design, thereby reducing costs, shortening waiting time, and meeting the needs of some patients for short-term, dynamic monitoring.

[0024] 2. This invention provides a lightweight bone loss detection instrument based on immune markers. The drive base rotates to the outside of the outer shell. The user places the blood collection needle into the base and then drives the drive device to rotate the base back to the inside of the outer shell, aligning it with the puncture hole. The user places the fingertip of the finger to be blooded into the blood collection port with the fingertip facing down. The telescopic rod pushes the blood collection needle upward through the puncture hole to complete the puncture treatment of the fingertip. Then, the drive device drives the base to move the blood collection needle to the outside of the outer shell. At this time, the blood flowing from the fingertip will fall into the test tube.

[0025] 3. This invention provides a lightweight bone loss detection instrument based on immune markers. When the driving device moves the blood collection needle after pricking to the outside of the outer shell, the micro air pump working position compresses the air bag to inflate and expand, squeezing the finger placed in the blood collection port to facilitate the collection of fingertip blood. Attached Figure Description

[0026] Figure 1 This is a schematic diagram of the structure of the present invention;

[0027] Figure 2 This is a structural schematic diagram of the present invention from another angle;

[0028] Figure 3 This is a schematic diagram of the structure of the blood collection needle, test tube, and test box of the present invention being moved to the outside of the outer shell;

[0029] Figure 4 This is a schematic diagram of the internal structure of the outer shell of the present invention;

[0030] Figure 5 This is a schematic diagram of the structure of the airbag during inflation according to the present invention;

[0031] Figure 6 This is a schematic diagram of the structure of the base and slide of the present invention;

[0032] Figure 7 This is a schematic cross-sectional view of the connection between the base and the slide of the present invention.

[0033] Figure 8This is a schematic diagram of the structure of the detection box in this invention;

[0034] Figure 9 This is a schematic cross-sectional view of the connection between the blood collection needle and the bottom sleeve of the present invention.

[0035] Figure 10 For the present invention Figure 9 A magnified structural diagram of point A in the middle.

[0036] In the diagram: 1. Outer shell; 2. Display screen; 3. Blood collection port; 4. Squeezing airbag; 5. Needle puncture hole; 6. Blood collection needle; 7. Base sleeve; 8. Drive device one; 9. Baffle one; 10. Lifting rod; 11. Movable groove; 12. Ball retainer; 13. Elastic block; 14. Slot one; 15. Test tube; 16. Base support; 17. Angled connecting block one; 18. Slide seat; 19. Block one; 20. Slot two; 21. Limiting slide groove; 22. Slide rod; 23. Baffle two; 24. Pipetting mechanism; 25. Detection box; 26. Detection strip; 27. Biosensor; 28. Angled connecting block two; 29. ​​Block two; 30. Slot three; 31. Baffle three. Detailed Implementation

[0037] The present invention will be further described in detail below with reference to embodiments:

[0038] Example:

[0039] like Figure 1-10 As shown, the present invention provides a lightweight bone loss detection instrument based on immune markers, including a housing 1, a display screen 2 installed on the top of the housing 1, mainly used to display test results and operation instructions, and a sample introduction mechanism for controlling the entry and exit of the sample to be tested inside the housing 1.

[0040] The testing facility detects the immunomarkers contained in the sample to be tested. The casing 1 is equipped with a pipetting mechanism 24, which is used to draw the sample to be tested and drop it into the testing facility.

[0041] The data processing mechanism uses a microprocessor for processing. The microprocessor in this application is an ARM Cortex-M series microprocessor used to process and analyze the detection signals, quantitatively analyze the concentration of biomarkers, and assess the risk of bone loss in combination with parameters such as patient age and gender.

[0042] It also includes a power supply mechanism and a signal transmission module for power supply, data transmission and signal transmission. In this application, the signal transmission module mainly uses Bluetooth for transmission and can be used to transmit data to a mobile phone. In this application, the power supply mechanism uses a rechargeable lithium battery to power the entire device.

[0043] First, the sample to be tested is introduced into the interior of the outer casing 1 through the sample introduction mechanism. Then, the sample is pipetted into the detection mechanism 24, which is a prior art technology. The function of the pipetting mechanism 24 is to draw the sample and place it into the detection mechanism. Under the action of the detection mechanism, the immune markers contained in the sample are detected, and the detection data is transmitted to the data processing mechanism. Combined with parameters such as the patient's age and gender, the risk of bone loss is assessed. While ensuring the detection effect, the examination operation is simplified and the equipment structure is streamlined to achieve the purpose of lightweighting, thereby reducing costs, shortening waiting time, and meeting the needs of some patients for short-term, dynamic monitoring.

[0044] The sample to be tested can be saliva or fingertip blood. Saliva is non-invasive and easy to collect, while fingertip blood can be collected with a lancet, in small amounts, with a single blood collection volume of less than 50 μL.

[0045] Furthermore, the detection mechanism includes a detection box 25, with a detection strip 26 movably connected inside the detection box 25. A second inclined connecting block 28 is movably connected to one side of the detection box 25. The detection box 25 and the second inclined connecting block 28 are connected in a detachable manner, making it easy to remove the detection box 25 for cleaning. A biosensor 27 is fixedly connected to the second inclined connecting block 28, and a second locking block 29 is fixedly connected to the bottom of the second inclined connecting block 28. The second locking block 29 can slide along a third locking groove 30 opened inside the outer shell 1. A first driving mechanism is provided between the second locking block 29 and the third locking groove 30. This first driving mechanism is existing technology and includes gear drive, screw drive, etc. Any mechanism that can drive the detection box 25 to reciprocate along the third locking groove 30 is acceptable. The second inclined connecting block 28 has a certain width so that when the second inclined connecting block 28 moves to the outside of the outer shell 1, the detection box 25 can be completely exposed to the outside of the outer shell 1, thereby facilitating the replacement of the detection strip 26.

[0046] The detection box 25 moves along the slot 30 to the outside of the outer shell 1. The user puts the detection strip 26 into the detection box 25. The detection box 25 moves back to the inside of the outer shell 1 along the slot 30. The sample is detected by the biosensor 27, which is a photoelectric sensor or an electrochemical analyzer.

[0047] Furthermore, when the detection strip 26 is an LFIA strip carrying an antibody coating, the biosensor 27 is a photoelectric sensor, and gold nanoparticles or fluorescent markers are used to detect bone turnover markers. The detection results are transmitted to the data processing unit through the signal transmission module for centralized processing.

[0048] Furthermore, when the detection strip 26 is an electrode chip with surface-fixed antibodies, the biosensor 27 is an electrochemical analyzer. The biosensor 27 is electrically connected to the detection strip 26 and is used to monitor the changes in current or resistance caused by immune markers in the sample being tested. The monitoring results are transmitted to the data processing unit through the signal transmission module.

[0049] Furthermore, the immune markers in the outer shell 1 include bone formation: osteocalcin OC, N-terminal procollagen peptide P1 NP, bone resorption: C-terminal peptide CTX, deoxypyridinium phosphate DPD, and inflammatory factors: IL-6, TNF-α, or one or more of these.

[0050] Furthermore, the sample injection mechanism includes a base 16, in which a test tube 15 containing the sample to be tested is movably connected. A slanted connecting block 17 is movably connected to one side of the base 16, and a slide block 18 is movably connected to the bottom of the slanted connecting block 17. A locking block 19 is fixedly connected to the bottom of the slanted connecting block 17. A locking groove 20 is provided on the slide block 18, and the locking block 19 can slide along the locking groove 20. A driving mechanism 2 is provided between the locking block 19 and the slide block 18. This driving mechanism 2 is existing technology and includes gear drive, screw drive, etc. Any mechanism that can drive the locking block 19 to reciprocate along the locking groove 20 is acceptable.

[0051] The base 16 moves along the slot 20 to the outside of the outer shell 1. The user places the test tube 15 containing the sample to be tested into the base 16. The base 16 then moves back into the outer shell 1 along the slot 20. A limiting groove 21 is provided on the slide 18. A slide rod 22 is movably connected to the inner wall of the limiting groove 21. The slide 18 can drive the test tube 15 to move laterally along the slide rod 22. The driving method between the slide 18 and the slide rod 22 is existing technology, including screw drive, which facilitates subsequent operations on the sample to be tested.

[0052] Furthermore, a blood collection port 3 is provided on one side of the outer shell 1, and a needle puncture hole 5 is provided at the bottom of the inner cavity of the blood collection port 3. The blood collection port 3 is connected to the inner cavity of the outer shell 1 through the needle puncture hole 5. A blood collection needle 6 is movably connected to the bottom of the needle puncture hole 5. The blood collection needle 6 is a commonly used elastic blood collection needle in the prior art, which has the characteristics of smaller incision, faster speed and less pain. A bottom sleeve 7 is movably connected to the bottom end of the blood collection needle 6. A telescopic rod 10 is fixedly connected to the bottom of the inner cavity of the bottom sleeve 7. The telescopic rod 10 is a telescopic rod structure that can be driven by electricity in the prior art. The output end of the telescopic rod 10 is movably connected to the bottom of the blood collection needle 6. A drive device 8 is movably connected to one end of the bottom sleeve 7 through a shaft. The drive device 8 is fixedly connected to the inner wall of the outer shell 1.

[0053] The drive device 8 drives the base sleeve 7 to rotate to the outside of the outer shell 1. The user places the lancet 6 into the base sleeve 7, and then the drive device 8 drives the base sleeve 7 to rotate back to the inside of the outer shell 1, aligning it with the puncture hole 5. The user places the fingertip of the finger to be punctured into the puncture port 3 with the fingertip facing down. The telescopic rod 10 pushes the lancet 6 upward through the puncture hole 5 to complete the puncture treatment of the fingertip. Then, the drive device 8 drives the base sleeve 7 to move the lancet 6 to the outside of the outer shell 1. At this time, the blood flowing from the fingertip will fall into the test tube 15. Through the above structure, the user can complete the fingertip blood collection operation with one hand, avoiding the problem that the user cannot complete the blood collection smoothly due to insufficient hand dexterity.

[0054] Furthermore, a compression airbag 4 is fixedly connected to the top of the inner cavity of the blood collection port 3. A miniature air pump is installed inside the outer shell 1 to inflate and deflate the compression airbag 4. When the drive device 8 drives the bottom sleeve 7 to move the blood collection needle 6 after the needle is inserted to the outside of the outer shell 1, the miniature air pump inflates the compression airbag 4 and expands, squeezing the finger placed in the blood collection port 3 to facilitate the collection of fingertip blood.

[0055] Furthermore, multiple movable grooves 11 are provided on the inner wall of the bottom sleeve 7, and a retaining ball 12 is movably connected to the inner wall of each movable groove 11. An elastic block 13 is fixedly connected to the inner wall of the movable groove 11. Multiple retaining slots 14 are correspondingly provided on the outer surface of the blood collection needle 6. The retaining ball 12 and the retaining slot 14 form a retaining action, so that the blood collection needle 6 can be placed in the bottom sleeve 7 and remain stable.

[0056] Furthermore, the blood collection needle 6, test tube 15, and test strip 26 are all disposable consumables and need to be replaced after each test.

[0057] Furthermore, a second baffle 23 is movably connected to the outer surface of the outer shell 1 at the test tube 15 and the base 16; a third baffle 31 is movably connected to the outer surface of the outer shell 1 at the test box 25 and the test strip 26; and a first baffle 9 is movably connected to the outer surface of the outer shell 1 at the blood collection needle 6 and the base 7. All three baffles (1-9, 2-23, and 3-31) are connected to the outer shell 1 via elastic pivots. That is, when the blood collection needle 6, test tube 15, and test box 25 move outwards from the outer shell 1, they will push the first baffle 9, the second baffle 23, and the third baffle 31 open. When the blood collection needle 6, test tube 15, and test box 25 move into the interior of the outer shell 1, the first baffle 9, the second baffle 23, and the third baffle 31 will gradually spring back and close under the action of the elastic pivots. This is existing technology and will not be described in detail.

Claims

1. A lightweight bone loss detection device based on immune markers, characterized in that: Includes a housing (1), a display screen (2) is mounted on the top of the housing (1), and a sample injection mechanism for controlling the entry and exit of the sample to be tested inside the housing (1) is provided inside the housing (1); The testing institution detects the immunomarkers contained in the sample to be tested. The shell (1) is provided with a pipetting mechanism (24) for drawing the sample to be tested into the testing institution. The data processing unit is used to process and analyze the detection signals; It also includes a power supply mechanism and a signal transmission module, used for power supply, data transmission and signal transmission.

2. The lightweight bone loss detection instrument based on immune markers according to claim 1, characterized in that: The detection mechanism includes a detection box (25), a detection strip (26) is movably connected inside the detection box (25), a second inclined connecting block (28) is movably connected to one side of the detection box (25), a biosensor (27) is fixedly connected to the second inclined connecting block (28), a second locking block (29) is fixedly connected to the bottom of the second inclined connecting block (28), and the second locking block (29) can slide along the third locking groove (30) opened inside the outer shell (1); The detection box (25) moves along the slot three (30) to the outside of the shell (1). The user puts the detection strip (26) into the detection box (25). The detection box (25) moves back along the slot three (30) to the inside of the shell (1) and the sample is detected by the biosensor (27).

3. The lightweight bone loss detection instrument based on immune markers according to claim 2, characterized in that: When the detection strip (26) is an antibody-coated LFIA strip, the biosensor (27) is a photoelectric sensor used to detect the color and fluorescence changes of the detection strip (26), and to detect bone turnover markers using gold nanoparticles or fluorescent markers. The detection results are transmitted to the data processing unit through the signal transmission module.

4. A lightweight bone loss detection device based on immune markers according to claim 2, characterized in that: When the detection strip (26) is an electrode chip with surface-fixed antibodies, the biosensor (27) is an electrochemical analyzer used to monitor changes in current or resistance caused by immune markers in the sample being tested, and the monitoring results are transmitted to the data processing unit through a signal transmission module.

5. A lightweight bone loss detection device based on immune markers according to claim 1, characterized in that: The immune markers in the outer shell (1) include bone formation: osteocalcin (OC), N-terminal procollagen peptide (P1 NP), bone resorption: C-terminal peptide (CTX), deoxypyridinium phosphate (DPD), and inflammatory factors: one or more of IL-6 and TNF-α.

6. A lightweight bone loss detection device based on immune markers according to claim 1, characterized in that: The sample introduction mechanism includes a base (16), in which a test tube (15) containing the sample to be tested is movably connected. A first inclined connecting block (17) is movably connected to one side of the base (16), and a slide (18) is movably connected to the bottom of the first inclined connecting block (17). A first locking block (19) is fixedly connected to the bottom of the first inclined connecting block (17). A second locking groove (20) is provided on the slide (18), and the first locking block (19) can slide along the second locking groove (20). The base (16) moves along the second slot (20) to the outside of the outer shell (1). The user puts the test tube (15) containing the sample to be tested into the base (16). The base (16) then moves back to the inside of the outer shell (1) along the second slot (20). A limiting groove (21) is provided on the slide (18). A sliding rod (22) is movably connected to the inner wall of the limiting groove (21). The slide (18) can move the test tube (15) laterally along the sliding rod (22) to facilitate subsequent operations on the sample to be tested.

7. A lightweight bone loss detection device based on immune markers according to claim 6, characterized in that: A blood collection port (3) is provided on one side of the outer shell (1). A needle puncture hole (5) is provided at the bottom of the inner cavity of the blood collection port (3). The blood collection port (3) is connected to the inner cavity of the outer shell (1) through the needle puncture hole (5). A blood collection needle (6) is movably connected to the bottom of the needle puncture hole (5). A bottom sleeve (7) is movably connected to the bottom end of the blood collection needle (6). A telescopic rod (10) is fixedly connected to the bottom of the inner cavity of the bottom sleeve (7). The output end of the telescopic rod (10) is movably connected to the bottom of the blood collection needle (6). A drive device (8) is movably connected to one end of the bottom sleeve (7) through a shaft. The drive device (8) is fixedly connected to the inner wall of the outer shell (1). The drive device (8) drives the bottom sleeve (7) to rotate to the outside of the outer shell (1). The user puts the blood collection needle (6) into the bottom sleeve (7), and then drives the bottom sleeve (7) to rotate back to the inside of the outer shell (1) and the position aligned with the puncture hole (5). The user places the fingertip of the finger to be blooded down into the blood collection port (3). The telescopic rod (10) pushes the blood collection needle (6) up to complete the puncture treatment of the fingertip. Then the drive device (8) drives the bottom sleeve (7) to move the blood collection needle (6) to the outside of the outer shell (1). At this time, the blood flowing from the fingertip will fall into the test tube (15).

8. A lightweight bone loss detection device based on immune markers according to claim 7, characterized in that: The top of the inner cavity of the blood collection port (3) is fixedly connected to a compression airbag (4). The inner cavity of the outer shell (1) is equipped with a micro air pump for inflating and deflating the compression airbag (4). When the drive device (8) drives the bottom sleeve (7) to move the blood collection needle (6) after the needle is inserted to the outside of the outer shell (1), the micro air pump works to inflate the compression airbag (4), which inflates and squeezes the finger placed in the blood collection port (3), making it easier to collect blood from the fingertip.

9. A lightweight bone loss detection device based on immune markers according to claim 7, characterized in that: The inner wall of the base sleeve (7) is provided with multiple movable grooves (11), and each movable groove (11) is movably connected to a retaining ball (12). An elastic block (13) is fixedly connected to the inner wall of the movable groove (11). The outer surface of the blood collection needle (6) is provided with multiple retaining slots (14). The retaining ball (12) and the retaining slots (14) form a retaining action, so that the blood collection needle (6) can be placed in the base sleeve (7) and remain stable.

10. A lightweight bone loss detection device based on immune markers according to claim 7, characterized in that: The blood collection needle (6), test tube (15), and test strip (26) are all disposable consumables and need to be replaced after each test.

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