Biopsy sample intelligent storage device for hepatobiliary surgery department

Abstract

The invention discloses a hepatobiliary surgery biopsy sample intelligent storage device which comprises a storage box, a plurality of protection cups, a sample bottle, a cushioning mechanism and an intelligent control mechanism, the storage box is covered with a box cover, the protection cups are located in a sample storage area, the protection cups are fixedly connected to a first partition plate, water is contained in the protection cups, and the sample bottle is fixedly connected to the first partition plate. The box cover is fixedly connected with a sealing block matched with the protective cup; the specimen bottle is positioned in the protective cup; the cushioning mechanism comprises a storage battery, a liquid spraying box, a fixing box and a liquid conveying pump, and the storage battery is detachably installed on the storage box. According to the intelligent storage device for the biopsy samples for the hepatobiliary surgery department, the hepatobiliary biopsy samples can be protected in the transferring process, it is guaranteed that complete pathological sections can be manufactured subsequently, the authenticity of molecular detection results is guaranteed, then the accuracy and safety of clinical diagnosis are improved, and it is guaranteed that patients obtain correct diagnosis and effective treatment.

Description

Technical Field

[0001] This invention relates to the field of storage container technology, specifically to an intelligent storage device for biopsy samples used in hepatobiliary surgery. Background Technology

[0002] Hepatobiliary biopsy, as a core method for the precise diagnosis of hepatobiliary diseases, enables minimally invasive tissue sampling for pathological and molecular testing. This compensates for the limitations of imaging in identifying microscopic abnormalities and blood tests in localization, providing crucial evidence for disease diagnosis, treatment planning, and prognostic assessment. In my country's primary care and non-specialized hospitals, due to a lack of pathology equipment and qualified physicians, biopsy tissues must be sent to qualified institutions for testing.

[0003] Current methods for transporting liver and gallbladder samples involve placing ice or refrigeration equipment in storage boxes to maintain the temperature of the tissue specimens in the vials during transport. However, in actual transport, the bumps and vibrations from the vehicle can severely affect the integrity of the biopsy tissue, leading to two major problems.

[0004] First, the failure of tissue morphology testing can easily lead to misdiagnosis: because the bumps can cause the tissue to collide with the bottle wall, resulting in the tissue edges being broken or the intact tissue being fragmented. It is difficult to obtain complete pathological sections in the future, and doctors cannot accurately identify the subtle differences between cells, which can easily lead to misjudgment, resulting in overtreatment and irreversible damage to the patient's liver and gallbladder organs.

[0005] Secondly, vibrations during transport can damage cell structure, causing cell contents to leak out and resulting in nucleic acid degradation. This can lead to distorted results in molecular testing such as PCR and gene sequencing, especially in tumor mutation testing, where false positives or false negatives may occur. As a result, patients may miss valuable opportunities for targeted therapy or be given ineffective drugs, all of which can cause the patient's condition to continue to deteriorate, affecting their health and lifespan.

[0006] Therefore, in order to address the above-mentioned technical problems, it is necessary to provide an intelligent storage device for biopsy samples used in hepatobiliary surgery. Summary of the Invention

[0007] In view of the shortcomings of the prior art, the purpose of this invention is to provide an intelligent storage device for biopsy samples in hepatobiliary surgery to solve the problems mentioned in the background art.

[0008] To achieve the above objectives, a specific embodiment of the present invention provides an intelligent storage device for biopsy samples used in hepatobiliary surgery, comprising a storage box, multiple protective cups, specimen bottles, a shock-absorbing mechanism, and an intelligent control mechanism. The storage box is covered by a lid, and a first partition is fixedly connected inside the storage box, dividing it into a sample storage area and an equipment placement area. A refrigeration device is detachably installed on the storage box, and a first gas supply pipe is fixedly connected to the refrigeration device, with one end of the first gas supply pipe penetrating the storage box and extending into its interior. The protective cups are located in the sample storage area and are fixedly connected to the first partition. The protective cups contain water, and a sealing block matching the protective cup is fixedly connected to the lid. The specimen bottles contain formalin solution and are sealed with caps, located inside the protective cups. The shock-absorbing mechanism includes... The device includes a battery, a spray box, a mounting box, and an infusion pump. The battery is detachably mounted on a storage box and has a plug connected to it. A matching socket is fixedly installed on the storage box, and the infusion pump is electrically connected to the socket. The spray box is fixedly mounted on the bottom wall of a protective cup and has a second spray hole. The infusion pump is located within the equipment placement area, and a second infusion tube connected to the infusion pump is integrally formed on the spray box. The mounting box is fixedly connected to the protective cup and has a first drain hole. A second drain hole matching the first drain hole is also provided on the mounting box. A third infusion tube is fixedly connected to the mounting box, and the end of the third infusion tube away from the mounting box is fixedly connected to the infusion pump. The intelligent control mechanism includes a controller embedded in the box cover, which controls the start or stop of the infusion pump.

[0009] In one or more embodiments of the present invention, the shock-absorbing mechanism further includes a liquid equalizer, which is inserted into a protective cup. The liquid equalizer has a communicating cavity and a first spray hole. Multiple connecting pipes are fixedly connected to the liquid equalizer. An annular pipe is fixedly connected to one end of the multiple connecting pipes away from the liquid equalizer. A first infusion pipe is fixedly connected to the annular pipe. The end of the first infusion pipe away from the annular pipe is fixedly connected to an infusion pump.

[0010] In one or more embodiments of the present invention, a clamp is integrally formed on the liquid homogenizer, the distance between the clamp and the liquid homogenizer is matched with the wall thickness of the protective cup, and the liquid homogenizer is fastened to the protective cup by the clamp.

[0011] In one or more embodiments of the present invention, the liquid equalizer is provided with a liquid permeation section that matches the first drain hole, and a liquid level sensor that matches the liquid permeation section is fixedly connected to the sealing block. When the tank cover is closed on the storage tank, the liquid level sensor is inserted into the liquid permeation section. The liquid equalizer is integrally formed with multiple partition blocks, which divide the liquid equalizer into multiple spray sections that match the connecting pipe. The cavity is evenly distributed on the multiple spray sections, and a second solenoid valve that matches the spray section is fixedly connected to the connecting pipe.

[0012] In one or more embodiments of the present invention, a liquid distribution plate is fixedly connected inside the spray box, and the liquid distribution plate has a plurality of pressure equalization holes.

[0013] In one or more embodiments of the present invention, the end of the first gas supply pipe away from the refrigeration device is located in the equipment placement area, and the equipment placement area is provided with a temperature control component for adjusting the water temperature in the protective cup.

[0014] In one or more embodiments of the present invention, the temperature control component includes: a plurality of heat exchange tanks matched with the infusion pump, a gas distribution valve, and a temperature sensor; the heat exchange tanks are welded to the infusion pump, and the third infusion pipe passes through the heat exchange tanks; the gas distribution valve is fixedly connected to a first gas supply pipe, and a plurality of second gas supply pipes are fixedly connected to the gas distribution valve; one end of the second gas supply pipe away from the gas distribution valve is fixedly connected to the heat exchange tank; a first solenoid valve is fixedly connected to the second gas supply pipe; a fourth gas supply pipe communicating with the second gas supply pipe is fixedly connected to the heat exchange tank; a heat dissipation box is fixedly connected to the fourth gas supply pipe; the heat dissipation box has an air vent; and the storage tank has an air port communicating with the equipment placement area; the temperature sensor is fixedly connected to the first infusion pipe.

[0015] In one or more embodiments of the present invention, a second partition, a third partition, and a fourth partition are fixedly connected to the heat exchange tank. A liquid passage chamber is formed between the second partition and the heat exchange tank. A cooling chamber is formed between the second partition and the third partition. A liquid collection chamber is formed between the third partition and the fourth partition. The second gas delivery pipe is connected to the cooling chamber. The third liquid delivery pipe is connected to the liquid passage chamber. A plurality of liquid distribution pipes for guiding the liquid passage chamber and the liquid collection chamber are fixedly connected to the second partition and the third partition. A fourth liquid delivery pipe connected to the liquid collection chamber is fixedly connected to the heat exchange tank. The end of the fourth liquid delivery pipe away from the heat exchange tank is fixedly connected to the inlet of the liquid delivery pump.

[0016] In one or more embodiments of the present invention, a third gas supply pipe for connecting the cooling chamber and the gas collection chamber is fixedly connected to the third and fourth partitions, and the fourth gas supply pipe is connected to the liquid passage chamber.

[0017] In one or more embodiments of the present invention, the storage box is integrally formed with a first fixing frame and a second fixing frame, the battery is plugged into the first fixing frame, the refrigeration device is plugged into the second fixing frame, the refrigeration device is fixedly connected with a switch that matches the first gas supply pipe, the second fixing frame is fixedly connected with a quick connector, and the first gas supply pipe is detachably connected to the quick connector.

[0018] Compared with existing technologies, the intelligent storage device for hepatobiliary biopsy samples of the present invention can protect hepatobiliary biopsy samples during transportation. It can not only prevent the tissue edges of the hepatobiliary biopsy samples from breaking or the intact tissue from being fragmented due to vibration, but also prevent the contents of cells from flowing out due to vibration. This ensures the authenticity of the subsequent complete pathological sections and molecular test results, thereby improving the accuracy and safety of clinical diagnosis and ensuring that patients receive correct diagnosis and effective treatment. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 This is a schematic diagram of the structure of an intelligent storage device for biopsy samples used in hepatobiliary surgery according to one embodiment of the present invention. Figure 1 ; Figure 2 This is a schematic diagram of the structure of an intelligent storage device for biopsy samples used in hepatobiliary surgery according to one embodiment of the present invention. Figure 2 ; Figure 3 This is a cross-sectional view of an intelligent storage device for biopsy samples in hepatobiliary surgery according to an embodiment of the present invention; Figure 4 for Figure 3 Schematic diagram of the structure at point A; Figure 5 for Figure 3 Schematic diagram of the structure at point B; Figure 6 This is a schematic diagram of the shock-absorbing mechanism of an intelligent storage device for biopsy samples in hepatobiliary surgery, according to one embodiment of the present invention. Figure 1 ; Figure 7 This is a schematic diagram of the shock-absorbing mechanism of an intelligent storage device for biopsy samples in hepatobiliary surgery, according to one embodiment of the present invention. Figure 2 ; Figure 8This is a cross-sectional view of the protective cup of a smart storage device for biopsy samples in hepatobiliary surgery according to an embodiment of the present invention; Figure 9 This is a partial structural schematic diagram of the shock-absorbing mechanism of an intelligent storage device for biopsy samples in hepatobiliary surgery according to an embodiment of the present invention. Figure 10 This is a partial cross-sectional view of the shock-absorbing mechanism of an intelligent storage device for biopsy samples in hepatobiliary surgery according to an embodiment of the present invention. Figure 11 This is a cross-sectional view of the homogenizer of an intelligent storage device for biopsy samples in hepatobiliary surgery according to an embodiment of the present invention; Figure 12 This is a partial cross-sectional view of the temperature control component of an intelligent storage device for biopsy samples in hepatobiliary surgery according to an embodiment of the present invention. Figure 13 This is a cross-sectional view of the heat exchange tank of an intelligent storage device for biopsy samples in hepatobiliary surgery according to an embodiment of the present invention. Figure 14 This is a schematic diagram of the installation of the refrigeration tank of an intelligent storage device for biopsy samples in hepatobiliary surgery according to one embodiment of the present invention.

[0021] Explanation of reference numerals in the attached figures: 1. Storage box; 101. First partition; 102. Sample storage area; 103. Equipment placement area; 104. Gas inlet; 2. Box lid; 3. First mounting bracket; 4. Battery; 5. Plug; 6. Socket; 7. Electronic lock base; 701. Lock plate; 8. Controller; 9. Second mounting bracket; 10. Refrigeration device; 1001. First gas supply pipe; 1002. Gas distribution valve; 1003. Second gas supply pipe; 1004. First solenoid valve; 1005. Switch; 1006. Quick connector; 11. Sealing block; 12. Liquid level sensor; 13. Protective cup; 1301. First drain hole; 14. Liquid homogenizer; 1401. Cavity; 1402. First spray hole; 1403. Annular tube; 1404. Connecting tube; 1405. Second solenoid valve Valve; 1406, Liquid permeation section; 1407, Clamp; 1408, First infusion pipe; 1409, Divider block; 15, Spray box; 1501, Second infusion pipe; 1502, Second spray hole; 1503, Distributor plate; 16, Fixing box; 1601, Second drain hole; 1602, Third infusion pipe; 17, Infusion pump; 18, Heat exchange tank; 1801, Liquid passage chamber; 1802, Cooling chamber; 1803, Liquid collection chamber; 1804, Gas collection chamber; 19, Second partition; 20, Third partition; 21, Fourth partition; 22, Distributor pipe; 23, Third gas pipe; 24, Fourth gas pipe; 25, Fourth infusion pipe; 26, Heat dissipation box; 2601, Air jet hole; 27, Specimen bottle; 2701, Bottle cap; 28, Temperature sensor. Detailed Implementation

[0022] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0023] like Figures 1 to 8 As shown in one embodiment of the present invention, an intelligent storage device for biopsy samples in hepatobiliary surgery includes a storage box 1, a lid 2 covering the storage box 1, an electronic lock seat 7 installed on the storage box 1, and a locking plate 701 matching the electronic lock seat 7 on the lid 2. When the lid 2 is closed on the storage box 1, the electronic lock seat 7 and the locking plate 701 cooperate to lock the lid 2 onto the storage box 1. A first partition 101 is welded to the storage box 1, dividing the storage box 1 into a sample storage area 102 and an equipment placement area 103. Multiple protective cups 13 are installed in the sample storage area 102, and the multiple protective cups 13 are respectively adhered to the upper plate of the first partition 101. The protective cups 13 are filled with water. A sealing block 11 matching the protective cup 13 is adhered to the lid 2. When the lid 2 is closed on the storage box 1, the sealing block 11 presses on the protective cup 13 to seal the protective cup 13 and prevent the water inside the protective cup 13 from leaking out. A specimen bottle 27 for holding hepatobiliary biopsy samples is placed inside a protective cup 13. The specimen bottle 27 is filled with formalin solution and has a cap 2701 threaded onto it. A refrigeration device 10 is detachably installed on the storage box 1. The refrigeration device 10 is welded with a first gas supply pipe 1001, the end of which passes through the storage box 1 and extends into it. During the transport of hepatobiliary biopsy samples, liquid nitrogen from the refrigeration device 10 enters the storage box 1 through the first gas supply pipe 1001, maintaining a low temperature inside the storage box 1 and preventing the hepatobiliary biopsy sample tissue from autolyzing or deteriorating. The intelligent storage device for hepatobiliary biopsy samples also includes a shock-absorbing mechanism and an intelligent control mechanism. During the transport of hepatobiliary biopsy samples, the shock-absorbing mechanism reduces the vibration experienced by the specimen bottle 27, thereby protecting the hepatobiliary biopsy sample inside. The intelligent control mechanism includes a controller 8, which is embedded in the cover 2. The controller 8 and multiple infusion pumps 17 are electrically connected.

[0024] Specifically, such as Figures 3 to 10As shown, the shock absorption mechanism includes a battery 4, a spray box 15, a mounting box 16, and multiple infusion pumps 17. A first mounting bracket 3, matching the battery 4, is welded onto the storage box 1, and the battery 4 is inserted into the first mounting bracket 3. A plug 5 is electrically connected to the battery 4. A socket 6, matching the plug 5, is fixedly installed on the storage box 1 by bolts. Multiple infusion pumps 17 are electrically connected to socket 6, and the plug 5 is plugged into socket 6. The controller 8 can control the start or stop of multiple infusion pumps 17 individually. The spray box 15 is snapped onto the bottom wall of the protective cup 13. A second spray hole 1502 is opened on the spray box 15, and a second infusion pipe 1501, connected to the outlet of the infusion pump 17, is integrally formed on the spray box 15. The fixing box 16 is integrally formed on the protective cup 13. The protective cup 13 has a first drain hole 1301. The fixing box 16 has a second drain hole 1601 that matches the first drain hole 1301. A third infusion tube 1602 is welded on the fixing box 16. The end of the third infusion tube 1602 away from the fixing box 16 is connected to the inlet of the infusion pump 17.

[0025] Specifically, when transporting hepatobiliary biopsy samples, the samples are placed in specimen bottle 27 and cap 2701 is screwed on. The samples will sink within the bottle 27 until they reach the bottom of the cup. The specimen bottle 27 containing the samples is then placed into protective cup 13 and the lid 2 is closed. The bottle 27 gradually sinks to the bottom of protective cup 13. The infusion pump 17 is then activated, drawing water from protective cup 13 through the third infusion tube 1602 and spraying it from the second spray hole 1502. As water sprays from the second spray hole 1502, the water flow pushes the specimen bottle 27 upwards. During this upward movement within protective cup 13, the thrust exerted by the water flow from the second spray hole 1502 on the specimen bottle 27 gradually decreases, eventually causing the bottle 27 to float stably in the middle of protective cup 13. During transportation, even if the protective cup 13 is subjected to bumps and vibrations, the protective cup 13 and the specimen bottle 27 do not come into contact. With the buffering effect of water, the vibration experienced by the specimen bottle 27 will be greatly reduced, which can effectively protect the integrity of the liver and gallbladder biopsy sample inside the specimen bottle 27.

[0026] It should be noted that the specimen bottle 27 containing the liver and gallbladder biopsy sample has a weight of G, a buoyant force of F in the water, and a thrust of T from the water flow. Since F + T > G, the water jet at the second spray hole 1502 allows the specimen bottle 27 to float in the protective cup 13. As the specimen bottle 27 floats, the thrust from the water flow gradually decreases. When the specimen bottle 27 is located in the middle of the protective cup 13, the thrust from the water flow on the specimen bottle 27 is L, and F + L = G, thus allowing the specimen bottle 27 to float in the middle of the protective cup 13.

[0027] Preferably, specimen bottle 27 is a polypropylene bottle, whose density is slightly less than that of water. When specimen bottle 27 is filled with formalin solution and liver and gallbladder biopsy samples, its density will be slightly greater than that of water. Thus, when infusion pump 17 is started, the second spray hole 1502 does not need to spray excessively high water pressure to push specimen bottle 27 to float. The water in protective cup 13 is physiological saline, which is simple in composition, sterile, and suitable for medical use.

[0028] Furthermore, a liquid distribution plate 1503 is integrally formed inside the spray box 15. The liquid distribution plate 1503 has multiple pressure equalization holes. The pressure equalization holes can stabilize the water pressure inside the spray box 15 and ensure that the water pressure sprayed from the multiple second spray holes 1502 is consistent.

[0029] It is worth noting that during transportation, the specimen bottle 27 floating inside the protective cup 13 may collide with the cup wall of the protective cup 13. Furthermore, the shock absorption mechanism also includes a homogenizer 14, which is inserted into the protective cup 13. The homogenizer 14 has a connected cavity 1401 and a first spray hole 1402. Multiple connecting pipes 1404 are integrally formed on the homogenizer 14. An annular pipe 1403 is welded to the end of the multiple connecting pipes 1404 away from the homogenizer 14. A first infusion pipe 1408 is welded to the annular pipe 1403. The end of the first infusion pipe 1408 away from the annular pipe 1403 is welded to another outlet of the infusion pump 17. When the infusion pump 17 is started, it not only delivers water to the protective cup 13 through the second infusion tube 1501, but also delivers water to the homogenizer 14 through the first infusion tube 1408. The water entering the homogenizer 14 flows through the cavity 1401 and is sprayed out from the first spray hole 1402, which generates a thrust on the specimen bottle 27 in the protective cup 13, causing the specimen bottle 27 to float in the center of the protective cup 13. This prevents the specimen bottle 27 from moving laterally in the protective cup 13 and causing a collision, thus improving the protection of the liver and gallbladder biopsy samples in the specimen bottle 27.

[0030] A clamp 1407 is integrally formed on the liquid distributor 14. The distance between the clamp 1407 and the liquid distributor 14 matches the wall thickness of the protective cup 13. The liquid distributor 14 is fastened to the protective cup 13 by the clamp 1407. When the liquid distributor 14 is fastened to the protective cup 13, the lower part of the liquid distributor 14 can also abut against the spray box 15 at the bottom of the protective cup 13.

[0031] Furthermore, the liquid equalizer 14 is provided with a liquid permeation section 1406 that matches the first drain hole 1301. Water in the protective cup 13 can flow into the fixed box 16 through the liquid permeation section 1406, realizing water circulation in the protective cup 13. During the entire transportation process, the water in the protective cup 13 will not decrease or increase.

[0032] It is worth noting that during transportation, in addition to the vehicle's ability to withstand road bumps, the vehicle's acceleration or braking can also disrupt the stability of the water inside the protective cup 13. Especially when the vehicle brakes suddenly, the water inside the protective cup 13 tends to maintain its original state due to inertia, causing the water inside the protective cup 13 to move in the direction of the vehicle's movement. The specimen bottle 27 inside the protective cup 13 will also undergo the same movement, and the water flow sprayed from the first spray hole 1402 may not be able to prevent the collision between the specimen bottle 27 and the homogenizer 14.

[0033] Furthermore, such as Figures 2 to 11 As shown, a liquid level sensor 12, matching the liquid permeation section 1406, is welded onto the sealing block 11. When the cover 2 is closed on the storage tank 1, the liquid level sensor 12 is inserted into the liquid permeation section 1406. Multiple partition blocks 1409 are integrally formed on the liquid equalizer 14, dividing the liquid equalizer 14 into multiple spray sections that match the connecting pipe 1404. Cavities 1401 are evenly distributed on the multiple spray sections, and a second solenoid valve 1405 matching the spray section is fixedly connected to the connecting pipe 1404.

[0034] Specifically, when the vehicle brakes suddenly, the water in the protective cup 13 moves in the direction of vehicle travel. At this time, the water in the protective cup 13 will submerge the liquid level sensor 12 in the direction of vehicle travel. The liquid level sensor 12 sends a signal to the second solenoid valve 1405, which will automatically adjust its opening size to control the water flow from the connecting pipe 1404 into the spray section, increasing the water flow in the spray section corresponding to the direction of vehicle travel. This increases the thrust on the specimen bottle 27, preventing the specimen bottle 27 from colliding with the equalizer 14. Specifically, when the opening angle of one of the second solenoid valves 1405 increases, the opening angle of the other corresponding second solenoid valve 1405 decreases. When the thrust on one side of the specimen bottle 27 increases, the thrust on the other side decreases. This not only makes it easier to counteract the inertial force on the specimen bottle 27, but also maintains a stable flow of water from the annular pipe 1403.

[0035] It should be noted that there are at least four injection units, and even when the vehicle turns during driving, the four injection units can correspond to the four directions of east, west, south, and north respectively.

[0036] like Figure 3 , Figure 5 , Figure 6 , Figure 7 , Figure 12 and Figure 13As shown, the end of the first gas supply pipe 1001 away from the refrigeration unit 10 is located in the equipment placement area 103. The equipment placement area 103 is equipped with a temperature control component for adjusting the water temperature in the protective cup 13. The temperature control component includes a heat exchange tank 18 matched with the infusion pump 17, a gas distribution valve 1002, and a temperature sensor 28. The heat exchange tank 18 is welded to the infusion pump 17, and the third infusion pipe 1602 passes through the heat exchange tank 18. The gas distribution valve 1002 is welded to the first gas supply pipe 1001, and multiple second gas supply pipes 1003 are welded to the gas distribution valve 1002. The end of each second gas supply pipe 1003 away from the gas distribution valve 1002 is welded to the heat exchange tank 18, and a first solenoid valve 1004 is welded to each second gas supply pipe 1003. The refrigeration unit 10 discharges cold air, which is then diverted through the gas distribution valve 1002 and flows into each heat exchange tank 18 via the second gas supply pipe 1003. Since part of the third liquid supply pipe 1602 is also located within the heat exchange tank 18, the cold air in the heat exchange tank 18 and the water flowing in the third liquid supply pipe 1602 cool each other, thus lowering the water temperature. The cooled water flows into the protective cup 13, maintaining a lower temperature within the cup and thus cooling the specimen bottle 27. This allows for cryogenic preservation of liver and gallbladder biopsy samples during transport. Furthermore, because the specimen bottle 27 is submerged in water, the cooling effect is more uniform, which is beneficial for the storage of liver and gallbladder biopsy samples.

[0037] Furthermore, the temperature sensor 28 is welded to the first infusion tube 1408. When the cooled water flows from the first infusion tube 1408 into the protective cup 13, the temperature sensor 28 identifies the temperature of the water and controls the opening size of the first solenoid valve 1004 according to the temperature of the water flowing in the first infusion tube 1408, so that the water in each protective cup 13 can maintain a certain temperature, thereby ensuring that the biopsy sample in the specimen bottle 27 can be stored at a relatively stable temperature.

[0038] Preferably, the water temperature flowing into the protective cup 13 is 3.5°C, and after being conducted through the specimen bottle 27, the formalin temperature in the specimen bottle 27 is maintained at 4°C, which is the optimal temperature for protecting liver and gallbladder biopsy samples.

[0039] Furthermore, to enhance the heat exchange effect on the water, a second partition 19, a third partition 20, and a fourth partition 21 are integrally formed on the heat exchange tank 18. A liquid passage chamber 1801 is formed between the second partition 19 and the heat exchange tank 18, a cooling chamber 1802 is formed between the second partition 19 and the third partition 20, and a liquid collection chamber 1803 is formed between the third partition 20 and the fourth partition 21. The second gas supply pipe 1003 is connected to the cooling chamber 1802, and the third liquid supply pipe 1602 is connected to the liquid passage chamber 1801. Multiple distribution pipes 22 capable of connecting the liquid passage chamber 1801 and the liquid collection chamber 1803 are welded onto the second partition 19 and the third partition 20. A fourth liquid supply pipe 25 connected to the liquid collection chamber 1803 is welded onto the heat exchange tank 18, and the end of the fourth liquid supply pipe 25 away from the heat exchange tank 18 is welded to the inlet of the liquid pump 17. Water in the protective cup 13 flows from the third infusion tube 1602 into the liquid passage chamber 1801, and after being diverted by multiple distribution tubes 22, flows into the liquid collection chamber 1803, and then flows into the infusion pump 17 from the fourth infusion tube 25. Because the water in the third infusion tube 1602 is diverted by multiple distribution tubes 22, and the heat exchange area of ​​the cold air in the cooling chamber 1802 is increased, a better heat exchange effect can be achieved.

[0040] Preferably, the liquid separator 22 is a copper tube, and multiple fins are welded on the liquid separator 22 to further improve the heat exchange effect.

[0041] A third air supply pipe 23 for connecting the cooling chamber 1802 and the air collection chamber 1804 is welded on the third partition 20 and the fourth partition 21. A fourth air supply pipe 24 connected to the first solenoid valve 1004 is welded on the heat exchange tank 18. The cold air entering the cooling chamber 1802 can be discharged from the fourth air supply pipe 24, so that the cooling chamber 1802 can continuously receive cold air and ensure the heat exchange effect.

[0042] It is worth noting that when multiple infusion pumps 17 work together, the heat generated by each infusion pump 17 is relatively large, which will cause the temperature inside the storage tank 1 to rise. Furthermore, a heat sink 26 is welded onto the fourth gas pipe 24, and a jet hole 2601 is opened on the heat sink 26. The cold air flowing out of the cooling chamber 1802 is sprayed onto the infusion pump 17 through the jet hole 2601 to cool down the infusion pump 17 and prevent the temperature of the infusion pump 17 from rising when it is working, which would cause the temperature of the entire storage tank 1 to become too high.

[0043] Furthermore, such as Figure 1 , Figure 2 and Figure 12 As shown, the storage box 1 has an air vent 104 that is connected to the equipment placement area 103. The gas in the equipment placement area 103 will flow out from the air vent 104, carrying away the heat in the equipment placement area 103.

[0044] like Figures 1 to 3As shown, a first fixing frame 3 is integrally formed on the storage box 1, and the battery 4 is plugged into the first fixing frame 3. During the transportation of liver and gallbladder biopsy samples, if the battery 4 runs out of power, the plug 5 on the socket 6 can be unplugged and a new battery 4 can be replaced to ensure the continuous operation of the infusion pump 17. Of course, the infusion pump 17 can also be operated by connecting the power supply of the transport vehicle through the socket 6.

[0045] like Figure 2 , Figure 3 , Figure 5 and Figure 14 As shown, a second mounting bracket 9 is welded onto the storage box 1, and a refrigeration device 10 is inserted into the second mounting bracket 9. A switch 1005 matching the first gas supply pipe 1001 is fixedly installed on the refrigeration device 10, and a quick connector 1006 is welded onto the second mounting bracket 9. Preferably, the refrigeration device 10 can be a self-pressurized liquid nitrogen tank. Self-pressurized liquid nitrogen tanks have low operating costs and excellent cooling effect. When transporting liver and gallbladder biopsy samples, the switch 1005 is turned on, and the liquid nitrogen in the refrigeration device 10 is discharged into the cooling chamber 1802 to cool the dispensing pipe 22. After the liquid nitrogen in the refrigeration device 10 is consumed, the first gas supply pipe 1001 can be pulled out through the quick connector 1006, a new refrigeration device 10 can be replaced, and then the switch 1005 on the new refrigeration device 10 can be turned on.

[0046] It should be noted that after the liver and gallbladder biopsy sample is transported to the testing site and the specimen bottle 27 is taken out, the water in multiple protective cups 13 is poured out by flipping the storage box 1, and then disinfectant is injected into the protective cups 13 and each infusion pump 17 is started to circulate the disinfectant, thereby disinfecting the protective cups 13, the homogenizer 14, the spray box 15 and the fixing box 16. The disinfectant can also improve the disinfection effect after multiple cycles.

[0047] When using, such as Figures 1 to 8As shown, first, the specimen bottle 27 containing the liver and gallbladder biopsy sample is placed into the protective cup 13. Then, the box lid 2 is closed and the infusion pump 17 is started through the controller 8. After the infusion pump 17 is started, it draws water from the protective cup 13 and sprays it out from the first spray hole 1402 and the second spray hole 1502. The water flow from the second spray hole 1502 pushes the specimen bottle 27 upward, so that the specimen bottle 27 is suspended in the middle of the protective cup 13. The water flow from the first spray hole 1402 pushes the specimen bottle 27 to prevent the specimen bottle 27 from colliding with the homogenizer 14. During transport of hepatobiliary biopsy samples, even when the vehicle is traveling on bumpy roads, the specimen bottle 27 does not come into direct contact with other objects, which significantly reduces the vibration experienced by the hepatobiliary biopsy samples inside the specimen bottle 27. This not only ensures the integrity of the hepatobiliary biopsy sample tissue but also prevents damage to the cellular structure of the hepatobiliary biopsy sample, thus ensuring the accuracy of subsequent pathological analysis and molecular testing results. In turn, it improves the accuracy and safety of clinical diagnosis, ensuring that patients receive correct diagnosis and effective treatment.

[0048] Obviously, the above-described embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention also intends to include these modifications and variations.

Claims

1. An intelligent storage device for biopsy samples used in hepatobiliary surgery, characterized in that, include: Storage box (1), the storage box (1) is covered with a box lid (2), the storage box (1) is fixedly connected with a first partition (101), the first partition (101) divides the storage box (1) into a sample storage area (102) and an equipment placement area (103), the storage box (1) is detachably installed with a refrigeration device (10), the refrigeration device (10) is fixedly connected with a first gas supply pipe (1001), the end of the first gas supply pipe (1001) away from the storage box (1) passes through the storage box (1) and extends into the storage box (1); Multiple protective cups (13) are located in the sample storage area (102). The protective cups (13) are fixedly connected to the first partition (101). The protective cups (13) are filled with water. A sealing block (11) matching the protective cups (13) is fixedly connected to the lid (2). Specimen bottle (27), the specimen bottle (27) contains formalin solution, the specimen bottle (27) is sealed with a cap (2701), and the specimen bottle (27) is located inside a protective cup (13); The shock-absorbing mechanism includes a battery (4), a spray box (15), a fixing box (16), and an infusion pump (17). The battery (4) is detachably installed on the storage box (1). A plug (5) is electrically connected to the battery (4). A socket (6) matching the plug (5) is fixedly installed on the storage box (1). The infusion pump (17) is electrically connected to the socket (6). The spray box (15) is fixedly installed on the bottom wall of the protective cup (13). A second spray hole (1502) is opened on the spray box (15). The infusion pump (17) is located at the equipment placement. Within the zone (103), the spray box (15) is integrally formed with a second infusion tube (1501) connected to the infusion pump (17). The fixed box (16) is fixedly connected to the protective cup (13). The protective cup (13) has a first drain hole (1301). The fixed box (16) has a second drain hole (1601) that matches the first drain hole (1301). The fixed box (16) is fixedly connected with a third infusion tube (1602). The end of the third infusion tube (1602) away from the fixed box (16) is fixedly connected to the infusion pump (17). The intelligent control mechanism includes a controller (8) which is mounted on the box cover (2) and can control the start or stop of the infusion pump (17).

2. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 1, characterized in that, The shock-absorbing mechanism also includes a liquid equalizer (14), which is inserted into the protective cup (13). The liquid equalizer (14) has a cavity (1401) and a first spray hole (1402) that are connected to each other. Multiple connecting pipes (1404) are fixedly connected to the liquid equalizer (14). One end of the multiple connecting pipes (1404) away from the liquid equalizer (14) is fixedly connected to an annular pipe (1403). A first infusion pipe (1408) is fixedly connected to the annular pipe (1403). One end of the first infusion pipe (1408) away from the annular pipe (1403) is fixedly connected to the infusion pump (17).

3. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 2, characterized in that, The liquid homogenizer (14) is integrally formed with a clamp (1407), and the distance between the clamp (1407) and the liquid homogenizer (14) matches the wall thickness of the protective cup (13). The liquid homogenizer (14) is clamped to the protective cup (13) by the clamp (1407).

4. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 2, characterized in that, The liquid equalizer (14) is provided with a liquid permeation part (1406) that matches the first drain hole (1301). The sealing block (11) is fixedly connected with a liquid level sensor (12) that matches the liquid permeation part (1406). When the box cover (2) is closed on the storage box (1), the liquid level sensor (12) is inserted into the liquid permeation part (1406). The liquid equalizer (14) has multiple partition blocks (1409) integrally formed on it. The multiple partition blocks (1409) divide the liquid equalizer (14) into multiple spray sections that match the connecting pipe (1404). The cavity (1401) is evenly distributed on the multiple spray sections. A second solenoid valve (1405) that matches the spray section is fixedly connected to the connecting pipe (1404).

5. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 1, characterized in that, A liquid distribution plate (1503) is fixedly connected inside the spray box (15), and the liquid distribution plate (1503) has multiple pressure equalization holes.

6. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 2, characterized in that, The end of the first gas supply pipe (1001) away from the refrigeration device (10) is located in the equipment placement area (103), and the equipment placement area (103) is provided with a temperature control component for adjusting the water temperature in the protective cup (13).

7. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 6, characterized in that, The temperature control component includes: Multiple heat exchange tanks (18) that are matched with the infusion pump (17) are welded to the infusion pump (17), and the third infusion pipe (1602) passes through the heat exchange tank (18). Gas distribution valve (1002), which is fixedly connected to the first gas supply pipe (1001), and a plurality of second gas supply pipes (1003) are fixedly connected to the gas distribution valve (1002). The end of the second gas supply pipe (1003) away from the gas distribution valve (1002) is fixedly connected to the heat exchange tank (18). A first solenoid valve (1004) is fixedly connected to the second gas supply pipe (1003). A fourth gas supply pipe (24) connected to the second gas supply pipe (1003) is fixedly connected to the heat exchange tank (18). A heat dissipation box (26) is fixedly connected to the fourth gas supply pipe (24). A jet hole (2601) is opened on the heat dissipation box (26). An air port (104) connected to the equipment placement area (103) is opened on the storage box (1). Temperature sensor (28) is fixedly connected to the first infusion tube (1408).

8. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 7, characterized in that, A second partition (19), a third partition (20), and a fourth partition (21) are fixedly connected to the heat exchange tank (18). A liquid passage chamber (1801) is formed between the second partition (19) and the heat exchange tank (18). A cooling chamber (1802) is formed between the second partition (19) and the third partition (20). A liquid collection chamber (1803) is formed between the third partition (20) and the fourth partition (21). The second gas supply pipe (1003) is connected to the cooling chamber (1802). The third infusion pipe (1602) is connected to the infusion chamber (1801). Multiple distribution pipes (22) for guiding the infusion chamber (1801) and the collection chamber (1803) are fixedly connected to the second partition (19) and the third partition (20). A fourth infusion pipe (25) connected to the collection chamber (1803) is fixedly connected to the heat exchange tank (18). The end of the fourth infusion pipe (25) away from the heat exchange tank (18) is fixedly connected to the inlet of the infusion pump (17).

9. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 8, characterized in that, The third partition (20) and the fourth partition (21) are fixedly connected to a third gas supply pipe (23) for connecting the cooling chamber (1802) and the gas collection chamber (1804), and the fourth gas supply pipe (24) is connected to the liquid passage chamber (1801).

10. The intelligent storage device for biopsy samples in hepatobiliary surgery according to claim 1, characterized in that, The storage box (1) is integrally formed with a first fixing frame (3) and a second fixing frame (9). The battery (4) is inserted into the first fixing frame (3). The refrigeration device (10) is inserted into the second fixing frame (9). A switch (1005) matching the first gas supply pipe (1001) is fixedly connected to the refrigeration device (10). A quick connector (1006) is fixedly connected to the second fixing frame (9). The first gas supply pipe (1001) is detachably connected to the quick connector (1006).

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