Traditional Chinese medicine extract lotion for treating haemorrhoids and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine extract lotion for treating haemorrhoids and a preparation method of the traditional Chinese medicine extract lotion. The traditional Chinese medicine extracting solution is prepared from the following raw materials in parts by weight: 16-20 parts of garden burnet, 10-12 parts of sophora flowers, 8-10 parts of golden cypress, 8-10 parts of radix sophorae flavescentis, 6-8 parts of fig leaves, 5-8 parts of angelica sinensis and 5-8 parts of fructus kochiae. The preparation method comprises the following steps: crushing and sieving the raw material medicines, adding water, decocting and extracting, combining filtrate, and carrying out vacuum concentration. Through a scientific formula ratio and a synergistic effect of the traditional Chinese medicines, various symptoms such as bleeding, swelling and pain and itching caused by haemorrhoids can be effectively relieved. Moreover, the vacuum concentration process adopted by the invention can be used for concentrating at a relatively low temperature, so that the damage to heat-sensitive effective components is avoided, the stability of the obtained extracting solution is remarkably improved, the final curative effect of the product is ensured, and the problems of slow effect taking and poor stability of medicines in the prior art are solved.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine technology, specifically to a traditional Chinese medicine extract wash for treating hemorrhoids and its preparation method. Background Technology

[0002] Hemorrhoids are an extremely common anorectal disease with a high incidence rate, prevalent in both women and men. Its main symptoms include rectal bleeding, pain, swelling, and itching, causing significant suffering and severely impacting patients' quality of life.

[0003] Currently, treatments for hemorrhoids mainly include oral medications, topical preparations, surgery, and traditional Chinese medicine preparations. However, these existing treatments have significant limitations in terms of formulation, manufacturing process, and dosage form. At the formulation level, many existing therapies tend to focus on a single symptom, making it difficult to effectively address multiple accompanying symptoms such as bleeding, swelling, pain, and itching simultaneously through a comprehensive approach, resulting in incomplete treatment outcomes. At the manufacturing process level, traditional Chinese medicine preparations often employ methods such as heating at normal pressure during extraction and concentration. Excessive temperatures can easily lead to the degradation and destruction of heat-sensitive active ingredients, which not only reduces the final efficacy of the drug but also affects the chemical stability of the product. Furthermore, at the clinical application level, existing topical Chinese medicine preparations are relatively limited in dosage form, usually limited to washes or ointments. This cannot meet the diverse treatment needs of patients based on different types of hemorrhoids (such as internal or external hemorrhoids) or stages of the disease, such as rectal administration or local adhesive application, thus limiting the breadth and convenience of their clinical application.

[0004] Therefore, how to develop a novel drug with a scientific formulation that can achieve synergistic treatment of multiple targets, while employing a preparation process that can protect the activity of the active ingredients, and can be expanded into a variety of clinically applicable dosage forms to overcome the shortcomings of existing technologies has become a technical problem that urgently needs to be solved in this field. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides a traditional Chinese medicine extract wash for treating hemorrhoids and its preparation method, which solves the problems of slow onset of action and large side effects of existing hemorrhoid treatments, as well as the degradation of heat-sensitive active ingredients and poor product stability caused by improper processes in the preparation of traditional Chinese medicine preparations, thus affecting the final efficacy.

[0006] To achieve the above objectives, the present invention provides the following technical solution:

[0007] A traditional Chinese medicine extract wash for treating hemorrhoids, comprising a traditional Chinese medicine extract made from the following raw materials in parts by weight:

[0008] 16-20 parts of Sanguisorba officinalis;

[0009] 10-12 portions of locust flowers;

[0010] 8-10 parts of Phellodendron bark;

[0011] 8-10 parts of Sophora flavescens;

[0012] 6-8 portions of fig leaves;

[0013] 5-8 parts of Angelica sinensis;

[0014] 5-8 parts of Kochia scoparia fruit.

[0015] The herbal extract can be used to prepare a lotion for treating hemorrhoids.

[0016] The herbal extract can also be used to prepare suppositories for treating hemorrhoids. The active ingredient in the suppository can be absorbed through the rectum.

[0017] The herbal extract can also be used to prepare a gel for treating hemorrhoids. The gel formulation has the characteristic of local adhesion.

[0018] The pharmacological mechanism of the traditional Chinese medicine extract provided by this invention is as follows:

[0019] The components of Sanguisorba officinalis have been proven to have the effects of cooling the blood and stopping bleeding, detoxifying and astringing sores.

[0020] The components of Sophora japonica flowers have been proven to have the effect of cooling the blood and stopping bleeding.

[0021] The components of Phellodendron bark have been proven to have the effects of clearing heat and drying dampness, purging fire and detoxifying.

[0022] The components of Sophora flavescens have been proven to have the effects of clearing heat and drying dampness, killing parasites and relieving itching.

[0023] Fig leaf components have been proven to have the effects of clearing heat and detoxifying, reducing swelling and relieving pain.

[0024] Angelica sinensis has been proven to have the effects of nourishing blood, promoting blood circulation, regulating menstruation and relieving pain, and moistening the intestines and promoting bowel movements.

[0025] Kochia scoparia has been shown to have the effects of clearing heat and dampness, dispelling wind and relieving itching.

[0026] The combination of medicinal materials in this invention can achieve a comprehensive effect of cooling the blood and stopping bleeding, clearing heat and drying dampness, reducing swelling and relieving pain, moistening the intestines and promoting bowel movements, and improving local microcirculation.

[0027] A method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids includes the following steps:

[0028] S1. Raw Material Processing: Wash 16-20 parts of Sanguisorba officinalis, 10-12 parts of Sophora japonica, 8-10 parts of Phellodendron chinense, 8-10 parts of Sophora flavescens, 6-8 parts of fig leaves, 5-8 parts of Angelica sinensis, and 5-8 parts of Kochia scoparia separately to remove impurities and surface dust, and then place them in a cool, ventilated place to dry. This step is a pretreatment of the medicinal materials.

[0029] S2. Grinding and Sieving: The dried medicinal materials are ground into powder of suitable particle size and then sieved. This step makes the medicinal materials appear as powder, increasing the surface area. The powder can pass through a 60-100 mesh sieve.

[0030] S3. Water Extraction: Mix the pulverized medicinal powder evenly, place it in an extraction container, add water, soak for a certain period of time, then heat to boiling, decoct for a certain period of time, filter, and collect the filtrate; add water to the dregs again, repeat the decoction a certain number of times, each time for a certain period of time, filter, and combine the filtrates. The amount of water added to the medicinal materials can be in the range of 6-8 times, the soaking time can be in the range of 0.5-1 hour, and the decoction time can be in the range of 1-2 hours. The amount of water added to the dregs can be in the range of 4-6 times, the decoction can be repeated 1-2 times, and the decoction time can be in the range of 0.5-1 hour each time. The dregs can be decocted once more, each time for 0.5-1 hour.

[0031] S4. Vacuum Concentration: The combined filtrate is placed in a vacuum concentration apparatus and concentrated under specific temperature and pressure conditions until it is reduced to 1 / 2-1 / 3 of its original volume, yielding the herbal extract. This step utilizes reduced pressure to lower the boiling point and concentrate the extract. The vacuum concentration can be carried out at a temperature of 60-80℃ and a pressure of -0.05-0.08 MPa. The concentration can continue until the original volume is reduced to half.

[0032] This invention provides a traditional Chinese medicine extract wash for treating hemorrhoids and its preparation method. It has the following beneficial effects:

[0033] 1. The herbal extract provided by this invention uses seven medicinal herbs—Sanguisorba officinalis, Sophora japonica, Phellodendron chinense, Sophora flavescens, fig leaves, Angelica sinensis, and Kochia scoparia—in a compound formulation, with the weight proportions of each herb specifically combined. This combination achieves a comprehensive effect of cooling the blood and stopping bleeding, clearing heat and drying dampness, reducing swelling and relieving pain, moistening the intestines and promoting bowel movements, and improving local microcirculation. These multiple effects help alleviate clinical symptoms of hemorrhoids such as bleeding, swelling, pain, and itching.

[0034] 2. The preparation method of this invention increases the surface area of ​​the medicinal materials by pulverizing and sieving them, employs a multi-stage water extraction process to improve dissolution efficiency, and controls the temperature and pressure within a specific range during the vacuum concentration step. This control of process parameters helps to improve the extraction rate of effective components from the medicinal materials while avoiding the impact of high temperatures on heat-sensitive components, thereby helping to maintain the activity of the effective components in the extract and improve the stability of the extract.

[0035] 3. The herbal extract prepared by this invention can be used as an active ingredient in the preparation of lotions, suppositories, and gels. This multi-dosage form application expands the clinical application range of the extract, meeting patients' needs for different administration methods such as local washing, rectal administration, or topical application, and is suitable for local treatment of different types or stages of hemorrhoids. Detailed Implementation

[0036] The technical solutions of the present invention will be clearly and completely described below with reference to embodiments, comparative examples, and test examples. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0037] A traditional Chinese medicine extract wash for treating hemorrhoids, comprising a traditional Chinese medicine extract made from the following raw materials in parts by weight: 16-20 parts of Sanguisorba officinalis; 10-12 parts of Sophora japonica; 8-10 parts of Phellodendron chinense; 8-10 parts of Sophora flavescens; 6-8 parts of fig leaves; 5-8 parts of Angelica sinensis; and 5-8 parts of Kochia scoparia.

[0038] The herbal extract can be used to prepare a wash for treating hemorrhoids. It can also be used to prepare suppositories for treating hemorrhoids. The active ingredient in the suppository dosage form can be absorbed through the rectum.

[0039] The herbal extract can also be used to prepare a gel for treating hemorrhoids. The gel formulation has the characteristic of local adhesion.

[0040] The pharmacological mechanism of the traditional Chinese medicine extract provided by this invention is as follows:

[0041] The components of Sanguisorba officinalis have been proven to have the effects of cooling the blood and stopping bleeding, detoxifying and astringing sores.

[0042] The components of Sophora japonica flowers have been proven to have the effect of cooling the blood and stopping bleeding.

[0043] The components of Phellodendron bark have been proven to have the effects of clearing heat and drying dampness, purging fire and detoxifying.

[0044] The components of Sophora flavescens have been proven to have the effects of clearing heat and drying dampness, killing parasites and relieving itching.

[0045] Fig leaf components have been proven to have the effects of clearing heat and detoxifying, reducing swelling and relieving pain.

[0046] Angelica sinensis has been proven to have the effects of nourishing blood, promoting blood circulation, regulating menstruation and relieving pain, and moistening the intestines and promoting bowel movements.

[0047] Kochia scoparia has been shown to have the effects of clearing heat and dampness, dispelling wind and relieving itching.

[0048] The combination of medicinal materials in this invention can achieve a comprehensive effect of cooling the blood and stopping bleeding, clearing heat and drying dampness, reducing swelling and relieving pain, moistening the intestines and promoting bowel movements, and improving local microcirculation.

[0049] The preparation methods are as follows:

[0050] Examples 1-3:

[0051] Example 1:

[0052] This embodiment provides a method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids, the specific steps of which are as follows:

[0053] Raw material proportions and processing: Weigh out 16 parts of Sanguisorba officinalis, 10 parts of Sophora japonica, 8 parts of Phellodendron chinense, 8 parts of Sophora flavescens, 6 parts of fig leaves, 5 parts of Angelica sinensis, and 5 parts of Kochia scoparia. Wash each herb separately to remove impurities and surface dust, then place them in a cool, ventilated place to dry.

[0054] Grinding and sieving: Grind the dried medicinal materials from step 1 into powder and sieve the powder through a 60-mesh sieve.

[0055] Water extraction: Mix the sieved herbal powder from step 2 evenly, place it in an extraction container, add water equal to 6 times the total weight of the herbs, and soak for 1 hour. Then heat to boiling, decoct for 1 hour, filter, and collect the filtrate. Add water equal to 4 times the total weight of the herbs to the residue, and repeat the decoction once, each time for 0.5 hours, filter, and combine all the filtrates.

[0056] Vacuum concentration: The combined filtrate from step 3 is placed in a vacuum concentration apparatus and concentrated under vacuum conditions of 60°C and -0.05MPa until it is concentrated to 1 / 2 of its original volume, thus obtaining the herbal extract of the present invention.

[0057] Example 2:

[0058] This embodiment provides a method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids, the specific steps of which are as follows:

[0059] Raw material proportions and processing: Weigh out 20 parts of Sanguisorba officinalis, 12 parts of Sophora japonica, 10 parts of Phellodendron chinense, 10 parts of Sophora flavescens, 8 parts of fig leaves, 8 parts of Angelica sinensis, and 8 parts of Kochia scoparia. Remove impurities from each herb, rinse them quickly with clean water, dry them, grind them into coarse powder, and pass them through an 80-mesh sieve for later use.

[0060] Water extraction: Place the sieved herbal powder from step 1 into an extraction container, add water equal to 8 times the total weight of the herbs, and soak for 0.5 hours. Then heat to boiling, maintain a simmer for 2 hours, filter, and collect the filtrate. Add water equal to 6 times the total weight of the herbs to the dregs, decoct for 0.5 hours, filter, and combine all the filtrates.

[0061] Vacuum concentration: The combined filtrate from step 2 is placed in a vacuum concentration apparatus and concentrated under reduced pressure at a temperature of 80℃ and a pressure of -0.08MPa until it is concentrated to 1 / 3 of its original volume, thus obtaining the herbal extract.

[0062] Example 3:

[0063] This embodiment provides a method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids, the specific steps of which are as follows:

[0064] Raw material proportions and processing: Weigh out 18 parts of Sanguisorba officinalis, 8 parts of Sophora japonica, 8 parts of Phellodendron chinense, 10 parts of Sophora flavescens, 6 parts of fig leaves, 6 parts of Angelica sinensis, and 6 parts of Kochia scoparia. Remove impurities from each herb, rinse them quickly with clean water, dry them, grind them into coarse powder, and pass them through a 60-mesh sieve for later use.

[0065] Water extraction: Place the sieved herbal powder from step 1 into an extraction container, add water equal to 4 times the total weight of the herbs, and soak for 0.5 hours. Then heat to boiling, maintain a simmer and decoct for 1 hour, filter, and collect the filtrate. Add water equal to 6 times the total weight of the herbs to the residue, decoct for 1 hour, filter, and combine all the filtrates.

[0066] Vacuum concentration: The combined filtrate from step 2 is placed in a vacuum concentration apparatus and concentrated under vacuum conditions of 80℃ and -0.06MPa until it is concentrated to 1 / 2 of its original volume to obtain the herbal extract.

[0067] Comparative Examples 1-3:

[0068] Comparative Example 1:

[0069] Compared with Example 3, the difference is that Sanguisorba officinalis is not added, while the proportions of other raw materials and preparation process parameters are the same.

[0070] Comparative Example 2:

[0071] Compared with Example 3, the difference is that the amount of Sanguisorba officinalis was changed from 18 parts to 10 parts, while the other raw material ratios and preparation process parameters are the same.

[0072] Comparative Example 3:

[0073] Compared with Example 3, the difference is that atmospheric pressure heating concentration is used instead of vacuum concentration in the concentration step, while the other preparation process parameters are the same.

[0074] Test Example 1-3:

[0075] Test Example 1:

[0076] In vitro antibacterial effect comparison test:

[0077] This test case aims to verify the antibacterial effect of the traditional Chinese medicine extract formulation and its component ratio provided by the present invention.

[0078] Experimental materials:

[0079] Test samples: Traditional Chinese medicine extracts prepared in Example 3, Comparative Example 1, and Comparative Example 2.

[0080] Test strains: Staphylococcus aureus ATCC25923 and Escherichia coli ATCC25922, both purchased from China General Microbiological Culture Collection Center.

[0081] Culture media: Nutrient agar medium, MH agar medium.

[0082] Test method:

[0083] Preparation of bacterial suspension: Under aseptic conditions, single colonies of Staphylococcus aureus and Escherichia coli were picked and inoculated into liquid culture medium, respectively, and incubated with shaking at 37°C for 18-24 hours. Subsequently, the bacterial suspension was diluted to 0.5 McFarlane standard with sterile physiological saline for later use.

[0084] Plate preparation and inoculation: Take 100 μL of the prepared bacterial suspension and spread it evenly on the surface of MH agar medium plates.

[0085] Sample addition: Use a sterile punch to make 6 mm diameter holes in the inoculated culture medium plate. Take 100 μL of the extract samples from Example 3, Comparative Example 1, and Comparative Example 2 respectively, and add them to the different holes.

[0086] Cultivation and observation: Place the inoculated and sampled petri dishes in a 37℃ incubator for 18-24 hours. After cultivation, measure the diameter (mm) of the inhibition zone around each well using calipers. Repeat the experiment 3 times for each sample group.

[0087] Experimental results:

[0088] The results of the inhibition zone diameter measurements for each sample against the two strains are recorded in Table 1.

[0089] Table 1. Diameter of inhibition zones (mm) for each sample against the two bacterial strains

[0090]

[0091] The experimental data in Table 1 show that the herbal extract prepared in Example 3 exhibits inhibitory effects against both Staphylococcus aureus and Escherichia coli. The extracts from Comparative Examples 1 and 2 also showed inhibitory effects, but the measured diameters of their inhibition zones were smaller than those in Example 3.

[0092] Comparing the results of Example 3 with Comparative Example 1, the inhibitory effect of the extract on both bacterial strains decreased when the *Sanguisorba officinalis* component was absent. This indicates that *Sanguisorba officinalis* is one of the important components providing antibacterial activity in this formulation. Furthermore, comparing the results of Example 3 with Comparative Example 2, the antibacterial effect of the extract also weakened when the amount of *Sanguisorba officinalis* was less than 16 parts, suggesting that the weight ratio of *Sanguisorba officinalis* in the formulation is necessary to obtain the desired antibacterial effect.

[0093] The experimental results confirm the effectiveness of the traditional Chinese medicine composition provided by this technical solution. The components in the formula, such as Phellodendron bark and Sophora flavescens, possess heat-clearing and dampness-drying effects. Combined with the detoxifying and astringent effects of Sanguisorba officinalis, they collectively inhibit common bacterial strains associated with hemorrhoid infections. By limiting the weight proportions of each component, this multi-component synergistic effect is achieved, thereby helping to alleviate local inflammatory responses caused by bacterial infections.

[0094] Test Example 2:

[0095] Stability comparison test:

[0096] This test case aims to verify the effect of the vacuum concentration process on the stability of the traditional Chinese medicine extract in the preparation method provided by the present invention.

[0097] Experimental materials:

[0098] Test samples: Traditional Chinese medicine extracts prepared in Example 3 and Comparative Example 3.

[0099] Experimental equipment: constant temperature and humidity chamber, high performance liquid chromatograph (HPLC).

[0100] Reference standard: Berberine hydrochloride reference standard (purity ≥98%).

[0101] Test method:

[0102] Test conditions: The samples of Example 3 and Comparative Example 3 were subjected to accelerated testing at 40℃±2℃ and relative humidity of 75%±5%.

[0103] Sampling time: Samples were taken and tested in the 0th, 1st and 3rd months of the experiment.

[0104] Visual inspection: Visually observe the color, clarity, and presence of any precipitates in the sample.

[0105] Content determination: The content of berberine hydrochloride, an indicator component, in the sample was determined by high performance liquid chromatography.

[0106] Chromatographic conditions: C18 column (4.6 mm × 250 mm, 5 μm); mobile phase: acetonitrile-0.1% phosphoric acid aqueous solution; gradient elution; flow rate: 1.0 mL / min; detection wavelength: 345 nm; column temperature: 30 ℃.

[0107] Sample preparation: Accurately measure an appropriate amount of sample, dilute it with methanol to the specified concentration, filter it through a 0.45μm microporous membrane, and take the filtrate as the test solution.

[0108] Content calculation: Taking the content in month 0 as 100%, calculate the relative content of berberine hydrochloride in samples at subsequent time points.

[0109] Experimental results:

[0110] The stability test results of the samples of Example 3 and Comparative Example 3 under accelerated test conditions are recorded in Table 2.

[0111] Table 2. Stability test results of each sample under accelerated test conditions

[0112]

[0113] The experimental data in Table 2 show that, under accelerated testing conditions, the sample of Example 3 remained stable in properties for 3 months, with no precipitation, and the relative content of its indicator component, berberine hydrochloride, decreased only slightly. The sample of Comparative Example 3 showed a small amount of precipitation in the first month, with increased precipitate by the third month, and the relative content of berberine hydrochloride decreased more significantly than in Example 3.

[0114] Traditional Chinese medicine extracts are complex systems containing various chemical components. Some of these components are prone to oxidation, degradation, or polymerization at higher temperatures, leading to instability such as precipitation and reduced content of active ingredients. Comparative Example 3 used atmospheric pressure heating concentration, with an operating temperature close to the solvent's boiling point. Prolonged heating negatively impacted the structure and activity of heat-sensitive components.

[0115] The reduced-pressure concentration process employed in this technical solution allows the solvent to boil and evaporate within a temperature range of 60-80℃ by lowering the system pressure. This process reduces the temperature required for concentration operations and shortens the exposure time of the extract at high temperatures. Experimental results show that these process conditions slow down the degradation of heat-sensitive components and maintain the stability of the physical properties and chemical composition of the extract.

[0116] Test Example 3:

[0117] Clinical application effect observation:

[0118] This test case aims to observe the practical application effect of the traditional Chinese medicine extract prepared by this technical solution on typical symptoms of hemorrhoids.

[0119] Experimental materials and subjects:

[0120] Test sample: Traditional Chinese medicine extract prepared in Example 1.

[0121] Test subjects: Three subjects with one or more typical symptoms such as external hemorrhoids, rectal bleeding, pain, and itching were selected.

[0122] Test method:

[0123] Sample preparation and administration: Take the herbal extract prepared in Example 1 and heat it to 40°C before use. Instruct subjects to perform sitz baths 1-2 times daily.

[0124] Observation period: Each subject was observed for 10 to 15 consecutive days.

[0125] Observation indicators: Record the changes in symptoms of subjects before use and after the observation period, including the size of external hemorrhoids, bleeding, pain and itching.

[0126] Experimental results:

[0127] The changes in symptoms of the three subjects before and after the observation period are recorded in Table 3.

[0128] Table 3. Changes in symptoms before and after use in three subjects.

[0129]

[0130] Table 3 shows that after 10 to 15 days of application, the volume of external hemorrhoids in all three subjects decreased. Furthermore, the bleeding, pain, and itching symptoms experienced before use were reduced or eliminated after application.

[0131] The results indicate that the extract prepared by the formulation of this technical solution has multiple components that work synergistically to address various symptoms of hemorrhoids. Specifically, the blood-cooling and hemostatic functions of components such as Sanguisorba officinalis and Sophora japonica correspond to the observed reduction or cessation of bleeding. Components such as fig leaf, Phellodendron chinense, and Angelica sinensis, which respectively act to reduce swelling, clear heat, and promote blood circulation, are associated with the reduction in the size of external hemorrhoids and the alleviation of pain.

[0132] Furthermore, the wind-dispelling and antipruritic effects of Sophora flavescens and Kochia scoparia in the formula are consistent with the improvement of the subjects' itching symptoms. The experimental results confirm that the combination of traditional Chinese medicine extracts and its preparation method provided by this technical solution can obtain a final product that relieves various local symptoms of hemorrhoids, such as bleeding, swelling, pain, and itching.

Claims

1. A traditional Chinese medicine extract wash for treating hemorrhoids, characterized in that, Includes a traditional Chinese medicine extract, which is made from the following raw materials in parts by weight: 16-20 parts of Sanguisorba officinalis; 10-12 portions of locust flowers; 8-10 parts of Phellodendron bark; 8-10 parts of Sophora flavescens; 6-8 portions of fig leaves; 5-8 parts of Angelica sinensis; 5-8 parts of Kochia scoparia fruit.

2. The herbal extract wash for treating hemorrhoids according to claim 1, characterized in that, The herbal extract is used to prepare a lotion for treating hemorrhoids.

3. The herbal extract wash for treating hemorrhoids according to claim 1, characterized in that, The herbal extract is used to prepare suppositories for treating hemorrhoids.

4. The herbal extract wash for treating hemorrhoids according to claim 3 and its preparation method, characterized in that, The herbal extract is used to prepare a gel for treating hemorrhoids.

5. A method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids according to any one of claims 1-4, characterized in that, Includes the following steps: S1. Raw material processing: Wash 16-20 parts of Sanguisorba officinalis, 10-12 parts of Sophora japonica, 8-10 parts of Phellodendron chinense, 8-10 parts of Sophora flavescens, 6-8 parts of fig leaves, 5-8 parts of Angelica sinensis, and 5-8 parts of Kochia scoparia separately to remove impurities and surface dust, and then place them in a cool and ventilated place to dry. S2. Grinding and sieving: Grind the dried medicinal materials into powders of appropriate particle size and then sieve them. S3. Water extraction: Mix the pulverized medicinal powder evenly, put it into an extraction container, add water, soak for a certain period of time, then heat to boiling, decoct for a certain period of time, filter, and collect the filtrate; add water to the dregs again, repeat the decoction a certain number of times, each time for a certain period of time, filter, and combine the filtrates. S4. Vacuum Concentration: The combined filtrate is placed in a vacuum concentration device and concentrated under certain temperature and pressure conditions until it is concentrated to 1 / 2-1 / 3 of the original volume, thus obtaining the Chinese herbal extract.

6. The method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids according to claim 5, characterized in that, In step S2, the powder is passed through a 60-100 mesh sieve.

7. The method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids according to claim 5, characterized in that, In step S4, the vacuum concentration is carried out at a temperature of 60-80°C.

8. The method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids according to claim 5, characterized in that, In step S4, the pressure is -0.05 to -0.08 MPa.

9. The method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids according to claim 5, characterized in that, In step S3, add 6-7 times the amount of water to the medicinal materials, soak for 0.5-1 hour, then heat to boiling and decoct for 1-1.5 hours.

10. The method for preparing a traditional Chinese medicine extract wash for treating hemorrhoids according to claim 5, characterized in that, In step S3, add 4-5 times the amount of water to the dregs and boil them again 1-2 times, each time for 0.5-1 hour.

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