Tumor sampling device for treating tumors through combination of traditional Chinese medicine and western medicine

Abstract

The invention relates to the technical field of medical instruments, in particular to a tumor sampling device for treating tumors through combination of traditional Chinese medicine and western medicine, the tumor sampling device comprises a sleeve and a needle tube mounted at the bottom end of the sleeve, a crushing mechanism is arranged in the sleeve, the crushing mechanism comprises a rotating rod rotationally arranged in the sleeve, and a circular plate is mounted at the bottom end of the rotating rod; according to the device, the rotating rod is driven, the rotating rod drives the circular plate at the bottom end to linearly push towards a tumor and rotate around the axis of the circular plate, the circular plate drives the movable plate to synchronously move through the spring rod, and therefore the tumor can be accurately positioned; the movable plate drives the connecting rod and the cutting head to realize composite motion of propelling and rotating, and the elastic force of the spring to the movable seat enables the rubber rod to abut against the inner wall of the sleeve to generate stable friction resistance, so that the cutting strength can be automatically adjusted according to the resistance of tumor tissues, and excessive tissue fragmentation caused by hard cutting is avoided; therefore, the integrity of the tumor cells in the sample is ensured.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a tumor sampling device for the treatment of tumors using a combination of traditional Chinese and Western medicine. Background Technology

[0002] In the field of clinical diagnosis and treatment of tumors, the integration of traditional Chinese and Western medicine has become an important treatment direction due to its advantages in combining the syndrome differentiation and treatment of traditional Chinese medicine with the precision intervention of modern Western medicine. The premise of implementing this treatment model is to obtain sufficient and complete tumor tissue samples through tumor sampling in order to clarify the pathological type, molecular target and TCM syndrome, such as qi stagnation and blood stasis, phlegm and blood stasis, etc., so as to provide the core basis for the subsequent development of personalized treatment plans. Therefore, the performance of tumor sampling device directly affects the accuracy and effectiveness of the integrated Chinese and Western medicine treatment. Currently, most commonly used tumor sampling devices in clinical practice are based on Western medicine's puncture biopsy techniques, and are divided into two categories: negative pressure suction type and cutting type. The former uses negative pressure to aspirate tumor tissue, which is simple to operate and causes little damage to normal tissue, making it suitable for superficial soft tumors such as those in the breast, but the small sample volume may affect diagnosis; the latter relies on mechanical cutting to obtain intact tissue, which provides a sufficient sample volume and complete structure, making it suitable for deep or tough tumors such as those in the lungs and liver, but it requires high puncture precision and has a slightly higher risk of accidental injury.

[0003] However, the cutting or sampling components of existing devices are mostly rigid structures, which cannot dynamically adjust the force according to the texture of the tumor (such as myxoid degeneration of soft tissue tumors and fibrocalcifications of hard tissue tumors). For softer tumors (such as some sarcomas and metastatic adenocarcinomas), rigid cutting can easily lead to excessive tissue fragmentation, which not only destroys the cell morphology and tissue structure required for Western medicine pathological testing, but also affects the accuracy of traditional Chinese medicine in differentiating the nature of the tumor through samples (such as judging the abundance or deficiency of body fluids and the degree of blood stasis). For harder tumors (such as osteosarcoma and squamous cell carcinoma), the cutting force is insufficient to effectively obtain complete tissue, requiring multiple punctures, which increases the risk of trauma and infection for patients.

[0004] In view of this, we will study and improve the existing problems to provide a tumor sampling device that combines traditional Chinese and Western medicine for the treatment of tumors. The aim is to solve the problems and improve the practical value through this technology. Summary of the Invention

[0005] The purpose of this invention is to overcome the shortcomings of existing technologies and propose a tumor sampling device for the treatment of tumors using a combination of traditional Chinese and Western medicine.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a tumor sampling device for treating tumors using integrated traditional Chinese and Western medicine, comprising a cannula and a needle tube installed at the bottom end of the cannula. The cannula has a crushing mechanism inside, comprising a rotating rod rotatably disposed inside the cannula, a circular plate installed at the bottom end of the rotating rod, a movable plate rotatably disposed inside the cannula, a spring rod installed between the circular plate and the movable plate, an installation groove on the surface of the movable plate, a sliding seat sliding inside the installation groove, a rubber rod installed on the side of the movable seat near the inside of the cannula, a spring installed inside the installation groove, a guide plate installed at the bottom end of the circular plate, a sliding groove on the surface of the guide plate, one end of the movable seat sliding along the axial direction of the sliding groove, a connecting rod installed at the bottom end of the movable plate, and a cutting head installed at the bottom end of the connecting rod. A sampling mechanism is provided on one side of the sleeve. The sampling mechanism includes a sampling bottle installed on one side of the sleeve. A negative pressure tube is connected between the bottom end of the sampling bottle and the outer wall of the needle. A gas storage tube is movably provided below the circular plate. A squeezing rod that abuts against the movable plate slides inside the gas storage tube. An air cushion is installed inside the negative pressure tube. A connecting tube connects the gas storage tube and the air cushion. The outer wall of the connecting rod is equipped with a cleaning mechanism for collecting residual tumor samples inside the needle.

[0007] Preferably, a knob is installed at the top of the rotating rod, and the outer wall of the knob is provided with anti-slip texture.

[0008] Preferably, one end of the spring is fixedly connected to the side wall of the movable seat, and the other end of the spring is fixedly connected to the inner wall of the mounting groove.

[0009] Preferably, the top end of the cutting head is spherical, the bottom end of the cutting head is conical, and the outer wall of the top end of the cutting head is in close contact with the inner wall of the needle tube.

[0010] Preferably, the inner wall of the sleeve is provided with a limiting groove, the outer wall of the gas storage pipe is provided with a limiting plate, and one end of the limiting plate slides inside the limiting groove.

[0011] Preferably, an electric push rod is installed at the top of the sampling bottle, a piston is installed at the output end of the electric push rod, and graduation lines are provided on the surface of the sampling bottle.

[0012] Preferably, the cleaning mechanism includes a sliding plate that is slidably sleeved on the outer wall of the connecting rod, a take-up roller that is sleeved on the outer wall of the connecting rod, a sterile thread that is wound on the outer wall of the take-up roller, one end of the sterile thread that is fixed to the outer wall of the take-up roller, the other end of the sterile thread that is fixed to the top of the sliding plate, and a drive assembly for controlling the take-up and take-up of the sterile thread that is provided on the outer wall of the rotating rod.

[0013] Preferably, the drive assembly includes a sleeve with a cylindrical top, a ratchet fixed to the top of the cylinder, a magnet fixedly installed inside the ratchet, a rotating shaft rotatably mounted on the top of the sleeve via a one-way bearing, a pawl fitted on the top of the rotating shaft, the teeth of the pawl engaging with the outer peripheral teeth of the ratchet, a lever fixed to the side wall of the pawl, a spring inside the cylinder, one end of the spring fixedly connected to the inside of the cylinder, the other end of the spring fixedly connected to the top of the sleeve, and a torsion spring installed between the bottom end of the pawl and the top end of the sleeve.

[0014] Preferably, the rotating rod is made of magnetic material, the magnetic block is sleeved on the outer wall of the rotating rod, and the magnetic block and the rotating rod attract each other.

[0015] Compared with the prior art, the beneficial effects of the present invention are: 1. This invention utilizes a driving rod to propel a bottom circular plate linearly towards the tumor while rotating it around its own axis. The circular plate, via a spring rod, drives a movable plate to move synchronously. The movable plate then drives a connecting rod and a cutting head to achieve a combined propulsive and rotational motion, allowing the cutting head to pierce the tumor and screw in. Circumferential shear force is used to break and cut the tumor tissue. Simultaneously, the spring force on the moving seat causes the rubber rod to abut against the inner wall of the cannula, generating stable frictional resistance. When dealing with soft tumors, this resistance inhibits excessive shearing force from the cutting head, preventing excessive cell fragmentation. When dealing with hard tumors, the tumor's reverse resistance and the operator's thrust cause the circular plate to contract, the spring rod to compress, the moving seat to move upward, and the rubber rod to contract, reducing the contact pressure with the inner wall of the cannula and lowering frictional resistance. This ensures effective screwing in of the cutting head, automatically adjusting the cutting force according to the resistance of the tumor tissue. This avoids excessive tissue fragmentation or incomplete sampling due to hard cutting, thus ensuring the integrity of tumor cells in the sample and providing high-quality samples for subsequent pathological testing required for integrated traditional Chinese and Western medicine treatment.

[0016] 2. After the tumor cells are cut by the cutting head, the electric push rod at the top of the sampling bottle is activated. The push rod drives the piston to move upward along the inner wall of the sampling bottle, which increases the cavity inside the bottle and reduces the air pressure to form a negative pressure. This negative pressure is conducted to the needle tube through the negative pressure tube connected to the outer wall of the needle tube at the bottom of the sampling bottle, which draws in the cut tumor cells and delivers them to the sampling bottle. When a hard tumor is extracted, the resistance of the tumor to the cutting head and the force of the operator pushing the rotating rod cause the movable plate to contract towards the circular plate. The bottom of the movable plate pushes the squeezing rod in the gas storage tube to slide down. The squeezing rod squeezes the gas and sends it into the air cushion in the negative pressure tube through the connecting tube. The air cushion expands and reduces the effective flow area of ​​the negative pressure tube. With the initial negative pressure unchanged, the airflow inside the tube accelerates, and a stronger local negative pressure is formed at the connection between the negative pressure tube and the needle tube, which enhances the ability to adsorb and extract tumor cells. Thus, by automatically adjusting the negative pressure, no manual adjustment of equipment parameters is required, achieving sampling adaptability for different tumor types, expanding the scope of application of the device, avoiding the problem of incomplete sampling caused by the hard texture of tumors and insufficient adsorption, further improving sampling integrity, reducing the probability of secondary sampling, and reducing surgical trauma to patients.

[0017] 3. In this invention, when the rotating rod drives the circular plate, movable plate, and connecting rod to rotate, the rotating rod and the magnetic block inside the ratchet attract each other, causing the cylinder and ratchet to rotate synchronously. The pawl on the rotating shaft at the top of the sleeve meshes with the ratchet teeth. When the ratchet rotates, the pawl slides along the inclined surface of the ratchet teeth and compresses the torsion spring. At the same time, the spring inside the cylinder stores energy as it rotates. The connecting rod pushes the cutting head away from the needle tube, the seal between the two is released, the air pressure disappears, and the slide plate slides down the connecting rod due to gravity, pulling the sterile thread from the take-up roller. When the sampling is completed and the sterile thread is retrieved, the lever is moved to disengage the pawl from the ratchet. The spring releases its elasticity, causing the cylinder and take-up roller to rotate in the opposite direction, retrieving the sterile thread. The slide plate then moves upward and resets, squeezing the residual tumor sample in the needle tube and pushing it to the sampling bottle. This effectively prevents cross-contamination of samples when the same patient is sampled multiple times or when different patients are sampled consecutively. It provides accurate sample basis for subsequent pathological testing of samples and the formulation of traditional Chinese and Western medicine treatment plans, ensuring the accuracy of sample test results. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is one of the cross-sectional structural diagrams of the sleeve of the present invention; Figure 3 For the present invention Figure 2 Enlarged structural diagram of section A; Figure 4 This is a partial structural schematic diagram of the present invention; Figure 5 This is a schematic diagram of the sampling mechanism structure of the present invention; Figure 6 For the present invention Figure 5 Enlarged structural diagram of section B; Figure 7 This is a second schematic diagram of the cross-sectional structure of the sleeve of the present invention.

[0019] Legend: 1. Sleeve; 2. Needle; 3. Crushing mechanism; 31. Rotating rod; 32. Knob; 33. Circular plate; 34. Movable plate; 35. Mounting slot; 36. Moving seat; 37. Rubber rod; 38. Spring; 39. Guide plate; 310. Slide groove; 311. Connecting rod; 312. Cutting head; 313. Spring rod; 4. Sampling mechanism; 41. Sampling bottle; 42. Negative pressure tube; 43. Gas storage tube; 44. Squeezing rod; 45. Air cushion; 46. Connecting tube; 47. Electric push rod; 48. Piston; 5. Cleaning mechanism; 51. Slide plate; 52. Take-up roller; 53. Sterile thread; 54. Cylinder; 55. Ratchet; 56. Rotating shaft; 57. Pawl; 58. Spring; 59. Magnetic block. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0021] See Figures 1 to 7 As shown, the present invention provides a tumor sampling device for the treatment of tumors using a combination of traditional Chinese and Western medicine, including a cannula 1 and a needle tube 2 installed at the bottom end of the cannula 1. The cannula 1 is provided with a crushing mechanism 3, which includes a rotating rod 31 rotatably disposed inside the cannula 1. A circular plate 33 is installed at the bottom end of the rotating rod 31. A movable plate 34 is rotatably disposed inside the cannula 1. A spring rod 313 is installed between the circular plate 33 and the movable plate 34. An installation groove 35 is opened on the surface of the movable plate 34. A movable seat 36 slides inside the installation groove 35. A rubber rod 37 is installed on the side of the movable seat 36 near the inside of the cannula 1. A spring 38 is installed inside the installation groove 35. A guide plate 39 is installed at the bottom end of the circular plate 33. A sliding groove 310 is opened on the surface of the guide plate 39. One end of the movable seat 36 slides along the axial direction of the sliding groove 310. A connecting rod 311 is installed at the bottom end of the movable plate 34. A cutting head 312 is installed at the bottom end of the connecting rod 311. It should be noted that, based on the tumor location determined by preoperative imaging, the staff holds the device and aligns the needle 2 with the tumor site. The needle 2 is first inserted into the patient's body and pushed towards the tumor until its tip contacts the tumor surface, completing the pre-sampling positioning and puncture preparation. Next, the staff drives the rotating rod 31, causing it to move the bottom circular plate 33 linearly towards the tumor. The rotating rod 31 also rotates around its own axis. As the circular plate 33 moves, power is transmitted through the spring rod 313 connecting the circular plate 33 and the movable plate 34, causing the spring rod 313 to move synchronously. The movable plate 34 rotates, and the movable plate 34 drives the connecting rod 311 at its bottom end and the cutting head 312 at the bottom end of the connecting rod 311 to achieve a combined pushing and rotating motion consistent with the circular plate 33. This allows the cutting head 312 to pierce the tumor and continuously rotate and advance into the tumor. During this process, the cutting head 312 gradually cuts the internal cells of the tumor tissue through circumferential shearing force, completing the fragmentation and cutting of the tumor tissue. At this time, because the spring 38 always exerts elastic pressure on the moving seat 36, the moving seat 36 drives the front end of the rubber rod 37 to continuously abut against the inner sidewall of the sleeve 1. This abutting action will affect the movable plate 34 and the cutting head 312. The advance and rotation of the cutting head 312 generate stable frictional resistance. When facing a softer tumor, this frictional resistance can effectively suppress the excessive shearing force generated by the rapid rotation of the cutting head 312, preventing excessive fragmentation of tumor cells. However, when sampling a harder tumor, the tumor's own hardness will generate a large reverse resistance to the rotation of the cutting head 312. At this time, under the combined action of the tumor's reverse resistance and the operator's continuous pushing of the circular plate 33, the circular plate 33 will retract towards the movable plate 34, and the spring rod 313 will be compressed accordingly, causing the moving seat 36 to move upward along the groove 310 on the surface of the guide plate 39. At this time, the rubber rod 37... The moving seat 36 retracts into the mounting groove 35 due to the reaction force of the inner wall of the sleeve 1. It slides along the mounting groove 35 and compresses the spring 38. The contraction of the rubber rod 37 reduces the contact pressure with the inner wall of the sleeve 1, thereby reducing the frictional resistance to the rotation and advancement of the moving plate 34 and the cutting head 312. This ensures that the cutting head 312 can effectively screw into the hard tumor, thereby automatically adjusting the cutting force according to the resistance of the tumor tissue. This avoids excessive tissue fragmentation or incomplete sampling due to hard cutting, thus ensuring the integrity of the tumor cells in the sample and providing high-quality samples for the pathological testing required for subsequent integrated traditional Chinese and Western medicine treatment.

[0022] A sampling mechanism 4 is provided on one side of the sleeve 1. The sampling mechanism 4 includes a sampling bottle 41 installed on one side of the sleeve 1. A negative pressure tube 42 is connected between the bottom end of the sampling bottle 41 and the outer wall of the needle tube 2. A gas storage tube 43 is movably provided below the circular plate 33. A squeezing rod 44 that abuts against the movable plate 34 slides inside the gas storage tube 43. An air cushion 45 is installed inside the negative pressure tube 42. A connecting tube 46 is connected between the gas storage tube 43 and the air cushion 45. It should be noted that after the cutting head 312 completes the cutting of tumor cells, the electric push rod 47 installed at the top of the sampling bottle 41 is activated. The output end of the electric push rod 47 drives the piston 48 to move upward at a constant speed along the inner wall of the sampling bottle 41. As the piston 48 moves upward, the volume of the cavity inside the sampling bottle 41 gradually increases, and the internal air pressure decreases accordingly, forming a stable negative pressure environment. Since the bottom of the sampling bottle 41 is connected to the outer wall of the needle tube 2 through the negative pressure tube 42, this negative pressure environment will be conducted to the needle tube 2 through the negative pressure tube 42. The cut tumor cells are drawn into the needle tube 2 along its inner wall and then transported to the sampling bottle 41 via the negative pressure tube 42. When the tumor being sampled is a hard tumor, the hard tumor creates significant resistance to the insertion of the cutting head 312. As the operator continuously pushes the rotating rod 31, the movable plate 34 moves and retracts towards the circular plate 33. During this movement, the bottom end of the movable plate 34 continuously abuts against and pushes the squeezing rod 44 inside the gas storage tube 43, causing the squeezing rod 44 to slide downwards along the axial direction of the gas storage tube 43, squeezing... When rod 44 slides, it compresses the gas inside gas storage tube 43, transporting the compressed gas inside gas storage tube 43 to air cushion 45 installed inside negative pressure tube 42 through connecting tube 46. The continuous injection of gas causes air cushion 45 to expand continuously. The expanded air cushion 45 changes the space inside negative pressure tube 42, reducing the effective flow area of ​​negative pressure tube 42. According to the principle of fluid mechanics, with the initial negative pressure inside sampling bottle 41 unchanged, the reduction in flow area of ​​negative pressure tube 42 will increase the airflow speed inside the tube, thereby forming a stronger local negative pressure at the connection between negative pressure tube 42 and needle tube 2, enhancing the adsorption and extraction capacity of hard tumor cells, ensuring that hard tumor cells can be smoothly drawn into sampling bottle 41. Thus, by automatically adjusting the negative pressure, no manual adjustment of equipment parameters is required, achieving sampling adaptability for different tumor types, expanding the applicability of the device, avoiding the problem of incomplete sampling due to the hard texture of tumors and insufficient adsorption, further improving sampling integrity, reducing the probability of secondary sampling, and reducing surgical trauma to patients.

[0023] The outer wall of the connecting rod 311 is equipped with a cleaning mechanism 5 for collecting residual tumor samples inside the needle tube 2.

[0024] See Figure 2 As shown, a knob 32 is installed at the top of the rotating rod 31. The outer wall of the knob 32 is provided with anti-slip texture. The anti-slip texture design can increase the friction between the knob 32 and the hand, making it easier for the operator to rotate the rotating rod 31.

[0025] See Figure 4 As shown, one end of the spring 38 is fixedly connected to the side wall of the movable seat 36, and the other end of the spring 38 is fixedly connected to the inner wall of the mounting groove 35. When the cutting head 312 breaks up and samples the tumor, the spring 38 continuously applies a pushing force to the movable seat 36 through its own elasticity, so that the rubber rod 37 on the movable seat 36 is always in close contact with the inner wall of the sleeve 1.

[0026] See Figure 3 As shown, the top of the cutting head 312 is spherical, and the bottom is conical. The outer wall of the top of the cutting head 312 is in close contact with the inner wall of the needle tube 2. The conical bottom of the cutting head 312 can quickly pierce the tumor capsule with its sharp shape, reducing puncture resistance. At the same time, the conical edge can form a stable circumferential shear force when rotating, efficiently cutting the tumor tissue and improving the efficiency of fragmentation and sampling. The close contact between the spherical top of the cutting head 312 and the inner wall of the needle tube 2 can form a reliable seal throughout the entire process of the needle tube 2 entering the patient's body, effectively preventing blood, body fluids, etc. from entering the inside of the needle tube 2, avoiding sample contamination, and ensuring the accuracy of subsequent test results.

[0027] See Figures 5 to 6 As shown, a limiting groove is provided on the inner wall of the sleeve 1, and a limiting plate is fitted on the outer wall of the gas storage pipe 43. One end of the limiting plate slides inside the limiting groove. The limiting plate can restrict the circumferential rotation of the gas storage pipe 43, preventing the circular plate 33 and the movable plate 34 from rotating and causing the gas storage pipe 43 to rotate, thus ensuring that the extrusion rod 44 can act perpendicularly on the gas inside the gas storage pipe 43.

[0028] See Figure 5 As shown, an electric push rod 47 is installed at the top of the sampling bottle 41, and a piston 48 is installed at the output end of the electric push rod 47. The surface of the sampling bottle 41 is provided with scale lines. At the same time, the transparent design of the sampling bottle 41, together with the scale lines, allows for real-time observation of the sampling volume, which is convenient for medical staff to accurately control the sample collection volume according to the testing needs.

[0029] See Figure 7 As shown, the cleaning mechanism 5 includes a slide plate 51 that is slidably sleeved on the outer wall of the connecting rod 311. A take-up roller 52 is sleeved on the outer wall of the connecting rod 311. A sterile thread 53 is wound on the outer wall of the take-up roller 52. One end of the sterile thread 53 is fixed to the outer wall of the take-up roller 52, and the other end of the sterile thread 53 is fixed to the top of the slide plate 51. A drive assembly for controlling the take-up and release of the sterile thread 53 is provided on the outer wall of the rotating rod 31.

[0030] See Figure 7 As shown, the drive assembly includes a sleeve 1 with a cylinder 54 at its top. A ratchet 55 is fixed at the top of the cylinder 54. A magnet 59 is fixedly installed inside the ratchet 55. A rotating shaft 56 is provided at the top of the sleeve 1 via a one-way bearing. A pawl 57 is fitted at the top of the rotating shaft 56. The teeth of the pawl 57 are engaged with the outer teeth of the ratchet 55. A lever is fixed to the side wall of the pawl 57. A spring 58 is provided inside the cylinder 54. One end of the spring 58 is fixedly connected to the inside of the cylinder 54, and the other end of the spring 58 is fixedly connected to the top of the sleeve 1. A torsion spring is installed between the bottom end of the pawl 57 and the top end of the sleeve 1.

[0031] See Figure 7As shown, the rotating rod 31 is made of magnetic material, and the magnetic block 59 is sleeved on the outer wall of the rotating rod 31, and the magnetic block 59 and the rotating rod 31 attract each other.

[0032] It should be noted that during the sampling stage, when the rotating rod 31 drives the circular plate 33, the movable plate 34, and the connecting rod 311 to rotate, the rotating rod 31, being made of magnetic material, attracts the magnetic block 59 fixed inside the ratchet 55, thereby driving the cylinder 54 and the ratchet 55 to rotate synchronously. At this time, the pawl 57, which is mounted on the rotating shaft 56 at the top of the sleeve 1 via a one-way bearing, engages with the ratchet teeth on the outer periphery of the ratchet 55. When the ratchet 55 rotates, the pawl 57 slides along the inclined surface of the ratchet teeth and compresses the bottom torsion spring, without hindering the rotation of the ratchet 55. Simultaneously, the spring 58 inside the cylinder 54 gradually accumulates power as the cylinder 54 rotates. As the connecting rod 311 moves downward during the crushing and sampling process, it causes the cutting head 312 to leave the inside of the needle tube 2. The original seal between the cutting head 312 and the needle tube 2 is released, the air pressure disappears, and the sliding plate 51, under its own gravity... The lower connecting rod 311 slides downwards, causing the slide plate 51 to pull the sterile thread 53 from the take-up roller 52. When the sampling is completed and the sterile thread 53 needs to be retrieved, the lever on the side wall of the pawl 57 is moved, causing the teeth of the pawl 57 to disengage from the ratchet teeth of the ratchet 55. At this time, the spring 58 stored inside the cylinder 54 releases its elasticity, causing the cylinder 54 and the take-up roller 52 to rotate in the opposite direction, rewinding the sterile thread 53 onto the take-up roller 52. At the same time, the slide plate 51 moves upwards and resets as the sterile thread 53 is retrieved, so that the slide plate 51 squeezes the residual tumor sample inside the needle tube 2. The slide plate 51 can push the residual sample inside the needle tube 2 to the sampling bottle 41, thereby effectively preventing cross-contamination of samples when the same patient is sampled multiple times or when different patients are sampled consecutively. This provides accurate sample basis for subsequent sample pathological testing and the formulation of traditional Chinese and Western medicine treatment plans, ensuring the accuracy of sample test results.

[0033] Working principle: Based on the tumor location determined by preoperative imaging, the operator holds the device and aligns the needle 2 with the tumor. The needle 2 is inserted into the patient's body and pushed towards the tumor until its tip contacts the tumor surface, completing the pre-sampling positioning and puncture preparation. Next, the operator drives the rotating rod 31, causing the bottom circular plate 33 to move linearly towards the tumor. The rotating rod 31 also rotates around its own axis. As the circular plate 33 moves, a spring connecting the circular plate 33 and the movable plate 34... The rod 313 transmits power, causing the spring rod 313 to synchronously drive the movable plate 34 to rotate. The movable plate 34 then drives the connecting rod 311 at its bottom end and the cutting head 312 at the bottom end of the connecting rod 311 to achieve a combined pushing and rotating motion consistent with the circular plate 33. This allows the cutting head 312 to pierce the tumor, continuously spiraling and advancing into the tumor. During this process, the cutting head 312 gradually cuts the cells inside the tumor tissue through circumferential shearing force, completing the fragmentation and cutting of the tumor tissue. At this time, because the spring 38 constantly exerts elastic pressure on the movable seat 36, the movable... The seat 36 drives the front end of the rubber rod 37 to continuously abut against the inner sidewall of the sleeve 1. This abutting action generates stable frictional resistance to the advancement and rotation of the movable plate 34 and the cutting head 312. When facing a softer tumor, this frictional resistance can effectively suppress the excessive shearing force generated by the rapid rotation of the cutting head 312, avoiding excessive fragmentation of tumor cells. However, when sampling a harder tumor, the hardness of the tumor itself will generate a large reverse resistance to the insertion of the cutting head 312. At this time, the combined effect of the reverse resistance of the tumor and the continuous pushing of the circular plate 33 by the operator... When the circular plate 33 is in use, it will retract towards the movable plate 34, and the spring rod 313 will be compressed accordingly, causing the movable seat 36 to move upward along the slide groove 310 on the surface of the guide plate 39. At this time, the rubber rod 37 retracts into the mounting groove 35 due to the reaction force of the inner wall of the sleeve 1. The movable seat 36 slides along the mounting groove 35 and compresses the spring 38. The contraction of the rubber rod 37 reduces the contact pressure with the inner wall of the sleeve 1, thereby reducing the frictional resistance to the rotation and advancement of the movable plate 34 and the cutting head 312, ensuring that the cutting head 312 can effectively screw into the hard tumor. After the cutting head 312 completes the cutting of tumor cells, the electric push rod 47 installed at the top of the sampling bottle 41 is activated. The output end of the electric push rod 47 drives the piston 48 to move upward at a constant speed along the inner wall of the sampling bottle 41. As the piston 48 moves upward, the volume of the cavity inside the sampling bottle 41 gradually increases, and the internal air pressure decreases accordingly, forming a stable negative pressure environment. Since the bottom of the sampling bottle 41 is connected to the outer wall of the needle tube 2 through the negative pressure tube 42, this negative pressure environment will be conducted to the inside of the needle tube 2 through the negative pressure tube 42, drawing the cut tumor cells along the inner wall of the needle tube 2 and then transporting them to the sampling bottle 41 through the negative pressure tube 42. When the sample is a hard tumor, the hard tumor will generate greater resistance to the cutting head 312. Under the action of the operator continuously pushing the rotating rod 31, the movable plate 34 will move and retract to the side of the circular plate 33. During the movement of the movable plate 34... In the middle, its bottom end will continuously abut and push the squeezing rod 44 inside the gas storage tube 43, causing the squeezing rod 44 to slide downward along the axial direction of the gas storage tube 43. When the squeezing rod 44 slides, it will squeeze the gas inside the gas storage tube 43, and transport the compressed gas inside the gas storage tube 43 to the air cushion 45 installed inside the negative pressure tube 42 through the connecting tube 46. The continuous injection of gas causes the air cushion 45 to expand continuously. The expanded air cushion 45 will change the space inside the negative pressure tube 42 and reduce the effective flow area of ​​the negative pressure tube 42. According to the principle of fluid mechanics, under the condition that the initial negative pressure inside the sampling bottle 41 remains unchanged, the reduction of the flow area of ​​the negative pressure tube 42 will increase the airflow speed inside the tube, thereby forming a stronger local negative pressure at the connection between the negative pressure tube 42 and the needle tube 2, enhancing the adsorption and extraction ability of hard tumor cells, and ensuring that hard tumor cells can be smoothly drawn into the sampling bottle 41. During the sampling stage, when the rotating rod 31 drives the circular plate 33, the movable plate 34, and the connecting rod 311 to rotate, the rotating rod 31, being made of magnetic material, attracts the magnetic block 59 fixed inside the ratchet 55, thereby driving the cylinder 54 and the ratchet 55 to rotate synchronously. At this time, the pawl 57, which is mounted on the rotating shaft 56 at the top of the sleeve 1 via a one-way bearing, engages with the ratchet teeth on the outer periphery of the ratchet 55. When the ratchet 55 rotates, the pawl 57 slides along the inclined surface of the ratchet teeth and compresses the bottom torsion spring, without hindering the rotation of the ratchet 55. Simultaneously, the spring 58 inside the cylinder 54 gradually accumulates power as the cylinder 54 rotates. As the connecting rod 311 moves downward during the crushing and sampling process, it causes the cutting head 312 to leave the inside of the needle tube 2. The original seal between 312 and needle 2 is released, and the air pressure disappears. Under its own gravity, the slide plate 51 slides downward along the surface of the connecting rod 311, causing the slide plate 51 to pull the sterile thread 53 from the take-up roller 52. When the sampling is completed and the sterile thread 53 needs to be retrieved, the lever on the side wall of the pawl 57 is moved to disengage the teeth of the pawl 57 from the ratchet 55. At this time, the spring 58 stored inside the cylinder 54 releases its elasticity, causing the cylinder 54 and the take-up roller 52 to rotate in the opposite direction, rewinding the sterile thread 53 onto the take-up roller 52. At the same time, the slide plate 51 moves upward and resets as the sterile thread 53 is retrieved, so that the slide plate 51 squeezes the residual tumor sample inside the needle 2. The slide plate 51 can push the residual sample inside the needle 2 to the sampling bottle 41.

[0034] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A tumor sampling device for treating tumors using a combination of traditional Chinese and Western medicine, comprising a cannula (1) and a needle (2) installed at the bottom end of the cannula (1), characterized in that: The sleeve (1) is equipped with a crushing mechanism (3) inside. The crushing mechanism (3) includes a rotating rod (31) rotatably disposed inside the sleeve (1). A circular plate (33) is installed at the bottom end of the rotating rod (31). A movable plate (34) is rotatably disposed inside the sleeve (1). A spring rod (313) is installed between the circular plate (33) and the movable plate (34). An installation groove (35) is opened on the surface of the movable plate (34). A movable seat (36) slides inside the installation groove (35). A rubber rod (37) is installed on the side of the movable seat (36) near the inside of the sleeve (1). A spring (38) is installed inside the mounting groove (35). A guide plate (39) is installed at the bottom of the circular plate (33). A sliding groove (310) is opened on the surface of the guide plate (39). One end of the movable seat (36) slides along the axial direction of the sliding groove (310). A connecting rod (311) is installed at the bottom of the movable plate (34). A cutting head (312) is installed at the bottom of the connecting rod (311). A sampling mechanism (4) is provided on one side of the sleeve (1). The sampling mechanism (4) includes a sampling bottle (41) installed on one side of the sleeve (1). A negative pressure tube (42) is connected between the bottom end of the sampling bottle (41) and the outer wall of the needle tube (2). A gas storage tube (43) is movably provided below the circular plate (33). A squeezing rod (44) that abuts against the movable plate (34) slides inside the gas storage tube (43). An air cushion (45) is installed inside the negative pressure tube (42). A connecting tube (46) is connected between the gas storage tube (43) and the air cushion (45). The outer wall of the connecting rod (311) is provided with a cleaning mechanism (5) for collecting residual tumor samples inside the needle tube (2).

2. The tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 1, characterized in that: A knob (32) is installed at the top of the rotating rod (31), and the outer wall of the knob (32) is provided with anti-slip texture.

3. The tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 1, characterized in that: One end of the spring (38) is fixedly connected to the side wall of the movable seat (36), and the other end of the spring (38) is fixedly connected to the inner wall of the mounting groove (35).

4. A tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 1, characterized in that: The top of the cutting head (312) is spherical, and the bottom of the cutting head (312) is conical. The outer wall of the top of the cutting head (312) is in close contact with the inner wall of the needle tube (2).

5. A tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 1, characterized in that: The inner wall of the sleeve (1) is provided with a limiting groove, and the outer wall of the gas storage pipe (43) is fitted with a limiting plate, and one end of the limiting plate slides inside the limiting groove.

6. A tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 1, characterized in that: An electric push rod (47) is installed at the top of the sampling bottle (41), and a piston (48) is installed at the output end of the electric push rod (47). Graduation lines are opened on the surface of the sampling bottle (41).

7. A tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 1, characterized in that: The cleaning mechanism (5) includes a sliding plate (51) that is slidably sleeved on the outer wall of the connecting rod (311). A take-up roller (52) is sleeved on the outer wall of the connecting rod (311). A sterile thread (53) is wound on the outer wall of the take-up roller (52). One end of the sterile thread (53) is fixed to the outer wall of the take-up roller (52), and the other end of the sterile thread (53) is fixed to the top of the sliding plate (51). The outer wall of the rotating rod (31) is provided with a drive assembly for controlling the take-up and release of the sterile thread (53).

8. A tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 7, characterized in that: The drive assembly includes a sleeve (1) with a cylinder (54) at the top. A ratchet (55) is fixed at the top of the cylinder (54). A magnet (59) is fixedly installed inside the ratchet (55). A rotating shaft (56) is provided at the top of the sleeve (1) via a one-way bearing. A pawl (57) is fitted at the top of the rotating shaft (56). The teeth of the pawl (57) are engaged with the outer peripheral ratchet teeth of the ratchet (55). A lever is fixed to the side wall of the pawl (57). A spring (58) is provided inside the cylinder (54). One end of the spring (58) is fixedly connected to the inside of the cylinder (54). The other end of the spring (58) is fixedly connected to the top of the sleeve (1). A torsion spring is installed between the bottom end of the pawl (57) and the top end of the sleeve (1).

9. A tumor sampling device for integrated traditional Chinese and Western medicine treatment of tumors according to claim 8, characterized in that: The rotating rod (31) is made of magnetic material, and the magnetic block (59) is sleeved on the outer wall of the rotating rod (31), and the magnetic block (59) and the rotating rod (31) attract each other.

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