Environment-friendly high-barrier paper-based blister packaging sheet and preparation method thereof

Abstract

The invention relates to the technical field of packaging materials, in particular to an environment-friendly high-barrier paper-based blister packaging sheet and a preparation method thereof.The preparation method comprises the steps that the determination coefficient of cold stamping target parameters is adjusted according to blister types and blister area changes, and the judgment standard of subsequent consumption elongation and the spraying amount of an upper film heat sealing glue area are determined; on the basis of the predicted accumulated length difference, the influence of the correction tension change on lower film cold stamping and upper and lower film heat sealing is confirmed, or the corresponding unwinding rotating speed is corrected without breaking through the corresponding film roll strength error allowable range; and the consumption elongation is calculated according to the actual thickness of the lower film and the borne actual tension change, it is predicted that the reduction degree of the plastic deformation capacity of the lower film does not exceed the normal range, and cold stamping target parameters are adjusted, or when the reduction degree exceeds the normal range, the accumulated length difference is called back to break through the judgment standard of the corresponding error allowable range. According to the invention, a single paper-based material is used for replacing aluminum-plastic blister packaging, so that the consumption of non-renewable resources by packaging bag materials is reduced.

Description

Technical Field

[0001] This invention relates to the field of packaging materials technology, and in particular to an environmentally friendly high-barrier paper-based blister packaging sheet and its preparation method. Background Technology

[0002] Blister packaging is a unit-dose packaging method widely used in pharmaceuticals, food, cosmetics, and other fields. It offers advantages such as strong protection, ease of use, and portability. Its core structure typically consists of an upper film (covering layer) and a lower film (blister substrate), which are sealed together by heat and pressure to form a sealed cavity, protecting the contents from the influence of the external environment (such as moisture, oxygen, and light).

[0003] Chinese Patent Publication No. CN106696427A discloses a method for preparing a composite rigid sheet for tropical blister packaging. Specifically, a mixture of titanium dioxide, ytterbium fluoride, and zirconium oxide is ball-milled and calcined to obtain a filler. Dihexylamine and the filler are mixed, and then N-formylmorpholine, diethyl phosphonate, and benzimidazole are added and mixed. Diisoprene diepoxide, polyamide wax, and trimethylolpropane triacrylate are added sequentially to the mixture, and the mixture is stirred at 170°C for 5 minutes to obtain a composite. The composite is added to an extruder. A polyester film with a corona-treated surface is then extruded to prepare a composite polyester film. The composite polyester film is hot-pressed with aluminum foil to obtain an aluminum-plastic material. Finally, the aluminum-plastic material is extruded to obtain the composite rigid sheet for tropical blister packaging. Therefore, the method for preparing the composite rigid sheet for tropical blister packaging has the following problems:

[0004] Fixed parameters are difficult to adapt to material fluctuations and production demand standards, and the majority of aluminum-plastic blister packaging is inconvenient to recycle and not environmentally friendly. Summary of the Invention

[0005] Therefore, this invention provides an environmentally friendly high-barrier paper-based blister packaging sheet and its preparation method, in order to overcome the problems in the prior art where fixed parameters are difficult to adapt to material fluctuations and production demand standards, and aluminum-plastic blister packaging is inconvenient to recycle and is not environmentally friendly.

[0006] To achieve the above objectives, the present invention provides a method for preparing an environmentally friendly high-barrier paper-based blister packaging sheet, comprising:

[0007] The upper and lower films of the paper-based blister packaging sheet are wound into upper film rolls and lower film rolls. The cold stamping target parameters for cold stamping the lower film into bubbles are determined based on the differences in the layered structure of the lower film and the changes in the blister depth requirements.

[0008] The determination coefficient of the cold stamping target parameters is adjusted according to the blister type and blister area changes, and the criteria for determining the subsequent consumption elongation rate and the amount of coating on the heat-sealing adhesive area are determined.

[0009] The matching degree between the unwinding speed and the traction speed is determined based on the matching values ​​of the rotational speeds of the unwinding roller and the traction roller, and it is determined whether to adjust the unwinding speed and predict the cumulative length difference within the unwinding time.

[0010] Based on the predicted cumulative length difference exceeding the corresponding allowable range of membrane roll strength error, confirm the effect of tension change on the cold stamping of the lower membrane and the heat sealing of the upper and lower membranes, or, if it does not exceed the corresponding allowable range of membrane roll strength error, adjust the corresponding unwinding speed.

[0011] The consumption elongation rate is calculated based on the actual thickness of the lower film and the actual tension change. The degree of decrease in the plastic deformation capacity of the lower film is predicted. If it does not exceed the normal range, the cold stamping target parameters are adjusted. If it exceeds the normal range, the cumulative length difference is adjusted back to the judgment criteria that exceed the corresponding error allowable range.

[0012] Calculate the coverage deviation value by obtaining the conveying length of the upper and lower films after cold stamping and heat-sealing adhesive coating, and determine the degree of alignment deviation between the blister edge sealing area and the heat-sealing adhesive area.

[0013] The degree of alignment deviation is used to determine the deviation trend of the heat-sealing adhesive area and the sealing area of ​​the blister edge. The matching degree is adjusted according to the judgment criteria, or the defect points are marked to adjust the slitting sequence and the unwinding speed of the upper film roll.

[0014] Furthermore, the differences in the lower film layer structure include differences in actual thickness parameters and differences in material yield strength, and the cold stamping target parameters are the target stamping force and the target stamping speed.

[0015] Furthermore, the process of adjusting according to changes in blister type and blister area includes:

[0016] When the blister type changes, the target stamping force is reduced by decreasing the safety factor, and the target stamping speed is reduced by decreasing the reference speed.

[0017] When the area of ​​a single blister changes, the critical elongation rate is adjusted according to the increase / decrease / increase of the blister area, and the amount of several ring-shaped adhesive layers is adjusted according to the increase / decrease of the blister area.

[0018] Furthermore, the process of determining the degree of matching between the unwinding speed and the traction speed includes:

[0019] When the rotational speed matching value is less than or equal to the critical matching value, it is determined that the unwinding speed and traction speed are at the first matching degree, and it is predicted whether the cumulative length difference will exceed the error allowable range of the current lower film strength and the current upper film strength before the lower film roll and the upper film roll are unwound.

[0020] When the rotational speed matching value is greater than the critical matching value, it is determined that the unwinding speed and the traction speed are in the second matching degree, and the unwinding speed of the unwinding roller is adjusted according to the speed difference between the unwinding speed and the traction speed.

[0021] Further, calculate the cumulative length difference;

[0022] When the cumulative length difference is greater than or equal to the first standard value, it is predicted that the cumulative length will cause the tension change to exceed the safe range of the current lower film strength or the current upper film strength, and the unwinding speed of the corresponding unwinding roller is corrected.

[0023] When the cumulative length difference is less than the first standard value but greater than the second standard value, the effect of the corrected tension change on the cold stamping of the upper film and the heat sealing of the upper and lower films is confirmed.

[0024] Furthermore, the process of confirming the impact of corrective tension changes on the cold stamping of the upper film and the heat sealing of the upper and lower films includes:

[0025] The actual tension of the lower membrane is detected and the consumption elongation rate is calculated in combination with the material parameters of the lower membrane. When the consumption elongation rate is less than or equal to the critical elongation rate, it is predicted that the decrease in the plastic deformation capacity of the lower membrane under the current actual tension is not beyond the normal range.

[0026] When the consumption elongation rate is greater than the critical elongation rate, the predicted decrease in the plastic deformation capacity of the lower film under the current actual tension exceeds the normal range. Stamping according to the determined target stamping pressure and target stamping speed will cause the blister to fail to meet the requirements.

[0027] Furthermore, when the decrease is within the normal range, the target stamping force is increased based on the total elongation of the material and the elongation consumed, and the target stamping speed is decreased based on the change in the target stamping force.

[0028] Furthermore, when the decline exceeds the normal range, the first standard value is reduced based on the ratio of consumed elongation to total material elongation, and the unwinding speed of the unwinding roll is corrected.

[0029] Furthermore, the process of determining the impact of corrective tension changes on the cold stamping of the upper film and the heat sealing of the upper and lower films also includes:

[0030] The encoder installed on the traction roller detects the conveying length of the upper and lower films in real time after cold stamping and heat sealing coating, and calculates the coverage deviation value of the upper and lower film conveying lengths.

[0031] When the coverage deviation value is less than or equal to the deviation evaluation value, it is determined that the alignment deviation of the upper and lower films is within the normal range, and the deviation trend of the heat-sealing adhesive area and the blister edge sealing area is determined.

[0032] When the coverage deviation value is greater than the deviation evaluation value, it is determined that there is an alignment deviation between the upper and lower films, and the defect points are marked.

[0033] Furthermore, when there is an alignment deviation between the upper and lower films, the unwinding speed of the upper film roll is reduced or increased when the upper film conveying length is greater than or less than the lower film conveying length, based on the ratio of the coverage deviation value to the fixed duration.

[0034] After marking the defect location, the subsequent slitting device automatically rejects blister packs with alignment deviations by skipping a single slitting sequence for a fixed duration.

[0035] Furthermore, the production process of the upper and lower films is as follows: the coating liquid is applied to both sides of the paper base layer by roller coating or dip coating, and the coating is applied to both sides of the coated paper base layer. Depending on the requirements, it is determined whether to print varnish on the outside of the upper film, and then the upper film roll or the lower film roll is prepared by winding.

[0036] The upper film is cold-stamped according to the target parameters of cold stamping, and the lower film is coated with a heat-sealing adhesive layer. Then, they are assembled into blister packaging sheets by hot pressing.

[0037] Furthermore, the control parameters for the primer include the material movement speed and drying temperature;

[0038] The moving speed is less than or equal to 200 m / min, and the drying temperature is divided into three steps: the first step is 50-80℃, the second step is 70-100℃, and the third step is 90-120℃. The coating amount of the primer is 3-10 g / m². 2 / Single-sided.

[0039] Furthermore, the coating of the upper and lower films is vacuum-plated aluminum oxide. When printing on the upper or lower film, the printing speed is ≤350m / min, and the drying temperature after printing is 40-80℃.

[0040] Furthermore, the control parameters for applying the adhesive are the same as those for the primer, and the application rate of the heat-sealing adhesive is 5-10 g / m². 2 .

[0041] An environmentally friendly, high-barrier paper-based blister packaging sheet, comprising:

[0042] The upper film is a sealing and easy-to-open material. The structure of the sealing and easy-to-open material, from top to bottom, includes a varnish layer, an ink layer, a base coating layer, a paper base layer, a base coating layer, a plating layer, and a heat-sealing adhesive area.

[0043] The lower film is a foam material, and the structure of the foam material from top to bottom includes a varnish layer, an ink layer, a base coating layer, a paper base layer, a base coating layer, and a plating layer.

[0044] Furthermore, the weight parameter of the upper membrane ranges from 30g to 100g / m³. 2 The weight parameters of the lower membrane range from 60g to 400g / m³.2 ;

[0045] The barrier performance requirement for the prepared blister pack sheets is that the water vapor transmission rate is less than or equal to 2 g / (m²). 2 •24h), oxygen permeability less than or equal to 2cm 3 / (m 2 ·24h·0.1MPa).

[0046] Furthermore, polyvinyl alcohol coating is used as the primer, with a coating amount of 3-10 g / m² / layer; the plating layer uses aluminum oxide, and the heat-sealing adhesive has a coating amount of 5-10 g / m². 2 .

[0047] Compared with existing technologies, the beneficial effects of this invention are that, in the heat-sealing process of paper-based blister packaging, the differences in the layered structure (such as thickness, thermal conductivity, and adhesive layer distribution) between the upper film (easy-open layer) and the lower film (blister layer) directly affect the sealing quality. Traditional processes rely on fixed parameters (temperature, pressure, time), making it difficult to adapt to material fluctuations or production requirements. This invention employs dynamic adjustment logic, optimizing heat-sealing parameters by real-time monitoring of the physical state of the upper and lower films, ensuring sealing performance, ease of opening, and production efficiency.

[0048] Furthermore, during blister packaging production, changes in the film roll diameter directly affect the unwinding tension. As the film roll is continuously unwound, its diameter gradually decreases. Improper tension control can lead to film stretching and deformation, edge wrinkling, or film loosening, misalignment, decreased alignment accuracy, and heat sealing misalignment. This method uses torque control to adjust the rotation speed and maintain the linear speed of the upper and lower film rolls, ensuring stable conveying of the upper and lower films.

[0049] Furthermore, the main differences between capsule-type and tablet-type blister packs lie in their shape, depth / height (H), length-to-diameter ratio (L / D), and profile. Under the same conditions, larger blister types and areas require materials with better plastic deformation capabilities, resulting in higher elongation requirements and a greater risk of breakage. For the same blister type, changes in blister size and spacing require replacement of the corresponding cold stamping mold, but simultaneously alter the blister area ratio per unit area. This also changes the impact on the cold stamping of the paper-based lower film and creates a chain reaction in subsequent processes. This method adjusts the cold stamping parameters of the lower film and the heat-sealing adhesive coating parameters of the upper film according to the changes in the blister pack, correspondingly changing the criteria for determining subsequent elongation consumption. Through systematic adjustments, the cold stamping process remains stable after changing the blister type or size, producing high-quality, high-barrier packaging products.

[0050] Furthermore, as the film roll diameter decreases, the speed ω of the unwinding roller increases. However, if the initial speed matching is poor, the length difference L will continue to accumulate, leading to either film looseness or excessive tightness. The length of the lower film between the unwinding roller and the traction roller will continuously increase, resulting in increasing tension on the lower film. This method first determines the matching degree between the unwinding speed and the traction speed by using the speed matching value to determine whether to adjust the unwinding speed of the unwinding roller. At the same time, based on whether the predicted cumulative length difference will exceed the corresponding error allowable range, if it is confirmed that the cumulative length difference will exceed the corresponding error allowable range, the unwinding speed of the corresponding unwinding roller is corrected. This ensures the linear speed matching accuracy of the upper and lower film rolls in blister production, avoiding material failure or process failure caused by cumulative length errors.

[0051] Furthermore, the thickness variation of the paper base of the lower film affects the elastic modulus variation. Greater thickness requires higher stamping pressure but reduces elongation. Simultaneously, under the same tension, greater thickness results in a greater decrease in plastic deformation capacity and a lower tension tolerance. This invention divides the length variation of the lower film into an elastic deformation portion (linear term in the formula) and a plastic deformation portion (non-linear term in the formula). Based on the principle that elastic deformation is recoverable and plastic deformation is irrecoverable, the remaining elongation is calculated according to the actual tension borne by the lower film to quantify the severity of the decrease in plastic deformation capacity. When the decrease is not severe, the dynamic stress impact is reduced by decreasing the initial stamping speed. When the decrease is severe (tension approaches the tension threshold corresponding to the yield strength), it reflects an error in the current safe range of lower film strength, making it unsafe to protect the lower film when there is length accumulation between the film roll and the traction roller. By changing the judgment criteria, the safe range is corrected, increasing the accuracy and adaptability of judging and optimizing the lower film conveying situation before cold pressing.

[0052] Furthermore, since both the upper and lower films may have accumulated lengths, the degree of difference in accumulated lengths can easily lead to deviations in heat sealing. It is also known that the upper and lower films of paper-based blister sheets exhibit recoverable elastic deformation. If the impact of accumulated lengths on deviations is detected before cold stamping and heat sealing adhesive application, errors due to elastic deformation can occur, leading to misjudgments. This method improves the accuracy of alignment deviation detection by separately detecting the conveying lengths of the upper and lower films after cold stamping and heat sealing adhesive application. Simultaneously, it considers whether tension changes and accumulated lengths in the conveying lengths of the upper and lower films lead to deviations. Combining the deviation level and trend, it determines whether to mark defect locations. Based on the deviation trend, it adjusts the speed matching criteria and the unwinding speed of the upper film roll according to the coverage deviation value, thereby reducing the degree of accumulated length differences between the upper and lower films. By discussing the impact of accumulated lengths in both upper and lower films, it examines whether excessive deviations occur between the blister edge sealing area of ​​the lower film and the heat sealing area of ​​the upper film, thus increasing adaptability to different deviation situations and the flexibility of heat sealing the upper and lower films of the packaging sheet.

[0053] Furthermore, most pharmaceutical / food blister packaging currently on the market is aluminum-plastic blister packaging. This is inconvenient to recycle and environmentally unfriendly. The product of this invention is a recyclable, environmentally friendly, high-barrier paper-based blister packaging material. The prepared blister packaging sheet is a single paper-based material with high barrier properties, heat-sealing performance, and is degradable, recyclable, and reusable, making it a recyclable and environmentally friendly alternative to aluminum-plastic blister packaging. It helps reduce the consumption of non-renewable resources by packaging materials, increases the interlayer bonding of paper through the base coating, and has low environmental pollution. Compared with traditional aluminum-plastic blister packaging, the blister packaging sheet of this invention has a paper-based composite layered structure. To avoid tearing damage to the lower film paper base layer during cold stamping, the composite paper base layer of the lower film has an interlaced distribution of blister packs during cold stamping. Attached Figure Description

[0054] Figure 1 This is a flowchart illustrating the preparation method of the environmentally friendly high-barrier paper-based blister packaging sheet in this embodiment of the invention;

[0055] Figure 2 This is a schematic diagram illustrating the preparation and winding of the film on the paper-based blister packaging sheet in an embodiment of the present invention;

[0056] Figure 3 This is a schematic diagram illustrating the preparation and winding of the lower film for paper-based blister packaging sheets in an embodiment of the present invention;

[0057] Figure 4 This is a schematic diagram of the initial stage of heat-sealing paper-based blister packaging sheets in an embodiment of the present invention;

[0058] Figure 5 This is a schematic diagram of the process at the end of the heat-sealing stage of the paper-based blister packaging sheet in an embodiment of the present invention;

[0059] Figure 6 This is a schematic diagram of the main structure of the upper and lower membranes in an embodiment of the present invention;

[0060] Figure 7 This is a schematic diagram of the main view structure of the lower film of another blister type in an embodiment of the present invention;

[0061] Figure 8 This is a schematic diagram of the layered structure of the composite paper base layer in an embodiment of the present invention;

[0062] In the diagram: 1-Upper film, 2-Lower film, 3-Medicine, 4-Upper film roll, 5-Lower film roll, 6-Feeding roller, 7-Traction roller, 8-Hot press plate, 9-Hot press mold, 10-Blister, 11-Slitting device, 12-Receiving device, 13-Drying device, 14-Coating liquid, 15-Liquid tank, 16-Doctor, 17-Pressure roller, 18-Printing roller, 101-Gloss layer, 102-Ink layer, 103-Base coating layer, 104-Paper base layer, 105-Coating layer. Detailed Implementation

[0063] To make the objectives and advantages of the present invention clearer, the present invention will be further described below with reference to embodiments; it should be understood that the specific embodiments described herein are merely for explaining the present invention and are not intended to limit the present invention.

[0064] Preferred embodiments of the present invention will now be described with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are merely illustrative of the technical principles of the present invention and are not intended to limit the scope of protection of the present invention.

[0065] It should be noted that in the description of this invention, the terms "upper", "lower", "left", "right", "inner", "outer", etc., which indicate directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings. This is only for the convenience of description and is not intended to indicate or imply that the device or element must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation of this invention.

[0066] Furthermore, it should be noted that, in the description of this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0067] Please see Figures 1-8 As shown, Figure 1 This is a flowchart illustrating the preparation method of the environmentally friendly high-barrier paper-based blister packaging sheet in this embodiment of the invention; Figure 2 This is a schematic diagram illustrating the preparation and winding of the film on the paper-based blister packaging sheet in an embodiment of the present invention; Figure 3 This is a schematic diagram illustrating the preparation and winding of the lower film for paper-based blister packaging sheets in an embodiment of the present invention; Figure 4 This is a schematic diagram of the initial stage of heat-sealing paper-based blister packaging sheets in an embodiment of the present invention; Figure 5 This is a schematic diagram of the process at the end of the heat-sealing stage of the paper-based blister packaging sheet in an embodiment of the present invention; Figure 6 This is a schematic diagram of the main structure of the upper and lower membranes in an embodiment of the present invention; Figure 7 This is a schematic diagram of the main view structure of the lower film of another blister type in an embodiment of the present invention; Figure 8 This is a schematic diagram of the layered structure of the composite paper base layer in an embodiment of the present invention.

[0068] To achieve the above objectives, the present invention provides a method for preparing an environmentally friendly high-barrier paper-based blister packaging sheet, characterized in that it comprises:

[0069] Step S1: Prepare the upper and lower films of the paper-based blister packaging sheet and wind them into an upper film roll and a lower film roll. Determine the cold stamping target parameters for cold stamping the lower film into a bubble based on the differences in the layered structure of the lower film and the changes in the blister depth requirements.

[0070] Step S2: Adjust the determination coefficient of the cold stamping target parameter according to the blister type and blister area change, and determine the judgment criteria for subsequent consumption elongation rate and the amount of spraying of the heat sealant area.

[0071] Step S3: Calculate the current roll diameter of the upper and lower film rolls in real time, and dynamically adjust the torque of the unwinding motor according to the current roll diameter. Adjust the unwinding speed of the unwinding roller through torque control to maintain the linear speed of the upper and lower film rolls.

[0072] Step S4: Obtain the unwinding speed of the unwinding roller and the traction speed of the traction roller, calculate the speed matching value, determine the matching degree between the unwinding speed and the traction speed, and determine whether to adjust the unwinding speed of the unwinding roller based on the matching degree.

[0073] Step S5: Predict whether the cumulative length difference generated under the current matching degree will exceed the error allowable range under the current lower film strength and current upper film strength within the unloading time, and correct the unwinding speed of the corresponding unwinding roller, or confirm the impact of the correction tension change on the cold stamping of the upper film and the heat sealing of the upper and lower films.

[0074] Step S6: Calculate the consumption elongation rate based on the actual thickness of the lower film and the actual tension change borne by the lower film, predict whether the decrease in the plastic deformation capacity of the lower film exceeds the normal range, and adjust the cold stamping target parameters or adjust the judgment criteria for the cumulative length difference exceeding the corresponding error allowable range.

[0075] Step S7: Obtain the conveying length of the upper and lower films after cold stamping and heat-sealing adhesive coating, calculate the coverage deviation value, and determine the degree of alignment deviation between the blister edge sealing area and the heat-sealing adhesive area.

[0076] Step S8: Determine the deviation trend of the heat-sealing adhesive area and the blister edge sealing area according to the degree of alignment deviation, adjust the matching degree judgment criteria, or mark the defect points, adjust the slitting sequence, and adjust the unwinding speed of the upper film roll.

[0077] The differences in the lower film layered structure include differences in actual thickness parameters and differences in material yield strength. The cold stamping target parameters are the target stamping force and the target stamping speed.

[0078] Specifically, in the heat-sealing process of paper-based blister packaging, the differences in the layered structure of the upper film (easy-open layer) and the lower film (blister layer) (such as thickness, thermal conductivity, and adhesive layer distribution) directly affect the sealing quality. Traditional processes rely on fixed parameters (temperature, pressure, time), making it difficult to adapt to material fluctuations or production requirements. This invention employs dynamic adjustment logic, optimizing heat-sealing parameters by real-time monitoring of the physical state of the upper and lower films, ensuring sealing performance, ease of opening, and production efficiency.

[0079] The upper film production process is as follows: the coating liquid is applied to both sides of the paper base layer by roller coating, a coating layer is applied to both sides of the coated paper base layer, and varnish is printed on the outer side of the upper film, and the upper film roll is prepared by winding.

[0080] The production process of the lower film is as follows: the coating liquid is applied to both sides of the paper base layer by dip coating, and a coating is applied to both sides of the coated paper base layer. Depending on the requirements, it is determined whether to print varnish on the outside of the lower film (generally no printing or only printing of LOGO). The lower film roll is then prepared by winding.

[0081] The upper and lower films are combined by heat-sealing to form blister packs. The preparation process of blister packs includes:

[0082] Blister forming: The lower film (blister material) is first cold stamped to form a recessed blister cavity in the mold to hold the medicine;

[0083] Product filling: After the lower film is formed, it enters the automatic filling line, and tablets, capsules and other products are accurately placed into the blister cavity;

[0084] Upper film alignment: The upper film (easy-open sealing layer) is aligned with the lower film through a tension control system to ensure that the heat-sealing area completely covers the blister opening;

[0085] Hot-press sealing (heat sealing): The hot-sealable adhesive layer of the upper film and the sealing area of ​​the blister edge of the lower film are bonded together under pressure after being preheated to the softening temperature by the hot press plate. The temperature of the upper and lower films is provided by the hot press plate and the hot press mold, and the upper and lower films are bonded together under pressure.

[0086] Cooling and slitting: The heat sealant is immediately cured by cooling rollers or air cooling system to lock the sealing strength. Then, the continuous blister packs are slitting into several blister packs according to the preset slitting sequence by a slitting device.

[0087] Process parameter description:

[0088] In this embodiment, the control parameters of the primer are the moving speed of the coating material and the drying temperature. The moving speed is ≤200m / min, and the drying temperature is divided into three steps: 50-80℃, 70-100℃, and 90-120℃.

[0089] The application rate of the primer is 3-10 g / m².2 / Single-sided, the coating of the upper and lower films is vacuum-plated aluminum oxide. When printing on the upper or lower film, the printing speed is ≤350m / min, and the drying temperature after printing is 40-80℃.

[0090] The control parameters for applying the adhesive are the same as those for the primer. The application rate of the heat-sealing adhesive is 5-10 g / m². 2 .

[0091] During implementation, when cutting the upper and lower films of the prepared blister packaging sheets, the sheets are widened according to the maximum width range of equipment such as printing machines, coating machines, and slitting machines to make large rolls to improve production efficiency, and then cut into small rolls as needed.

[0092] For example: The end customer uses a roll of film with a width of 200mm*500m / roll. During production, it is spliced ​​into a large roll of 200mm*4 + edge material 20 = 820mm, with a production length of 2000m. After completion, it is cut into 200mm*500m / roll according to the customer's requirements, for a total of 16 small rolls.

[0093] In this embodiment, because the lower film needs to be stamped into a concave shape to accommodate the tablets, it must have higher strength (impact resistance). The upper film is roller-coated, while the lower film is dip-coated with a suitable thickness of porous paper material. The paper bases of the upper and lower films are different, and due to the impact resistance requirements, the thickness of the lower film varies when producing blister packs of different sizes.

[0094] Based on the differences in the layered structure of the lower film, namely the differences in film thickness parameters and material yield strength, and combined with the changes in the required blister depth due to the size of the drug, the target parameters for cold stamping of blister formation are determined.

[0095] When the required blister depth changes, the corresponding blister mold needs to be replaced. At the same time, due to the change in the required blister depth, the required compressive strength of the lower film also changes, and the thickness of the paper base in the selected lower film layer structure will vary.

[0096] The actual thickness of the prepared lower film is detected and the yield strength of the lower film material is experimentally measured. The historical thickness of the lower film is obtained, the target stamping force and target stamping speed are calculated, and the stamping force and stamping speed are adjusted by a servo press.

[0097] Target stamping force = safety factor × actual thickness × material yield strength × stamping projected area, where the safety factor is 1.2~1.5, positively correlated with the actual thickness, the material yield strength is 50MPa, and the stamping projected area = πr 2 r is the radius of the stamping head;

[0098] Target stamping speed = reference speed × (reference thickness ÷ actual thickness) 0.5× (Reference depth ÷ Required blister depth), the reference speed mentioned in the implementation is 60 times / minute, the reference thickness is 200μm, and the reference depth is 6mm;

[0099] Specifically, the cold stamping process involves cold stamping the lower film using a blister mold and several corresponding stamping heads to stamp out several blister packs on the lower film.

[0100] After the lower film is cold-pressed and before the upper and lower films are heat-sealed, the tablets, capsules and other products are precisely placed into the cavities of several blister packs through the filling process.

[0101] The table below compares examples of cold stamping parameters after changes in required blister depth and actual thickness.

[0102]

[0103] Table 1 Comparison of Examples of Cold Stamping Parameters

[0104] In this embodiment, the blister types include capsule type and tablet type. When the blister type is changed from tablet type to capsule type, it is necessary to adjust the stamping force and stamping speed of the cold stamping of the lower film.

[0105] When the blister type changes, the target stamping force is reduced by decreasing the safety factor, and the target stamping speed is reduced by decreasing the reference speed.

[0106] The cross-sectional size of the drug determines the blister area. When the size of the drug changes in the horizontal direction, the blister area changes accordingly. At the same time, the blister spacing is positively correlated with the blister area. As the number of blister packs in the corresponding blister packaging changes, the proportion of blister area in a unit of lower film area changes synchronously.

[0107] The requirements for elongation are higher, the paper base is under greater load, the blister sealing area changes, and the size of the area that needs to be heat-sealed changes;

[0108] When the total area of ​​the packaging sheet remains unchanged, the change in the area of ​​a single blister pack will result in a positive correlation between the blister pack spacing and the impact of the stamping process. Therefore, the negative correlation between the number of blister packs and the change in the blister pack area is usually greater than that between the blister pack area and the blister pack area (i.e., when the blister pack area increases, the proportion of the blister pack area of ​​the film decreases, and vice versa).

[0109] When the area of ​​a single blister changes, adjust the criteria for determining the elongation rate and the amount of heat-sealing adhesive sprayed in the upper film area;

[0110] Specifically, the critical elongation rate is increased or decreased slightly depending on the size of the blister area, and the amount of several ring-shaped adhesive layers is increased or decreased slightly depending on the size of the blister area.

[0111] Specifically, the main differences between capsule-type and tablet-type blister packs lie in their shape, depth / height (H), length-to-diameter ratio (L / D), and profile. Under the same conditions, larger blister types and areas require materials with better plastic deformation capabilities, resulting in higher elongation requirements and a greater risk of breakage. For the same blister type, changes in blister size and spacing require replacement of the corresponding cold stamping mold, but simultaneously alter the blister area ratio per unit area. This changes the impact on the cold stamping of the paper-based lower film and subsequent processes, creating a chain reaction. This method adjusts the cold stamping parameters of the lower film and the heat-sealing adhesive coating parameters of the upper film based on changes in the blister pack, correspondingly altering the criteria for determining subsequent elongation consumption. Through systematic adjustments, the cold stamping process remains stable after changing the blister type or size, producing high-quality, high-barrier packaging products.

[0112] As the upper and lower films are unwound, their radii decrease continuously, which has an increasing impact on the tension of the unwound upper and lower films, resulting in greater tension on the upper and lower films.

[0113] Specifically, the rotational speed and angular velocity of the upper and lower film feeding rollers remain constant, while the linear velocity decreases. The rotational speed is adjusted in real time through torque control to maintain a constant linear velocity.

[0114] During implementation, the initial roll diameter, target tension range, and actual film thickness of the upper and lower films are obtained respectively. The number of unwinding turns is recorded by the encoder, and the actual linear velocity and actual angular velocity of the film roll are measured. The current roll diameter is calculated as 2 × actual linear velocity / actual angular velocity.

[0115] Specifically, the calculated dynamic torque is calculated as the median of the target tension range × the current roll diameter / 2, and the output of the unwinding servo motor of the film roll is adjusted according to the dynamic torque.

[0116] Example of a dynamic tension control process:

[0117] The initial roll diameter is 300mm, the median of the set tension range is 100N / m, and the corresponding initial torque is 100×0.3÷2=15N·m;

[0118] When the roll diameter is reduced to 150mm, the new torque = 100 × 0.15 ÷ 2 = 7.5 N·m. The unwinding servo motor reduces the torque from 15 N·m to 7.5 N·m, maintaining the tension at around 100 N / m.

[0119] If the torque is not adjusted, the tension will rise to 200 N / m, causing the film on the upper or lower membrane to be overstretched.

[0120] During the dynamic adjustment process with constant tension, the unwinding speed of the film roll will automatically change according to the motor torque-speed characteristic curve. When the torque decreases, the motor speed will automatically increase, which will drive the unwinding speed of the film roll to increase.

[0121] Specifically, in the blister packaging production process, changes in the film roll diameter directly affect the unwinding tension. As the film roll is continuously unwound, its diameter gradually decreases. If the tension is not properly controlled, it can lead to film stretching and deformation, edge wrinkling, or film loosening, misalignment, decreased alignment accuracy, and heat sealing misalignment. This method uses torque control to adjust the rotation speed and maintain the linear speed of the upper and lower film rolls to ensure stable conveying of the upper and lower films.

[0122] In this embodiment, the film roll consists of an upper film roll and a lower film roll.

[0123] The unwinding speed of the unwinding roller and the traction speed of the traction roller are acquired or calculated in real time to determine whether the rotation speeds are mismatched.

[0124] The unwinding speed = π × current roll diameter × unwinding speed; the traction speed = π × traction roller diameter × traction speed.

[0125] The rotational speed matching value is calculated based on the unwinding speed and the traction speed, wherein the rotational speed matching value = |unwinding speed - traction speed| ÷ traction speed;

[0126] When the rotational speed matching value is less than or equal to the critical matching value, it is determined that the unwinding speed and traction speed are at the first matching degree, and the rotational speed matching is good.

[0127] When the rotational speed matching value is greater than the critical matching value, it is determined that the unwinding speed and traction speed are in the second matching degree, indicating poor rotational speed matching.

[0128] During implementation, when the speed matching is poor, the unwinding speed of the unwinding roller is adjusted according to the speed difference between the unwinding speed and the traction speed. When the unwinding speed is greater than or less than the traction speed, the unwinding speed is reduced or increased.

[0129] When the rotation speed is well matched, predict whether the cumulative length difference will exceed the error allowable range of the current lower film strength and the current upper film strength before the lower film roll and the upper film roll are finished unloading, given the current degree of matching of the rotation speed difference.

[0130] During implementation, the material strength of the paper base material corresponding to the actual film thickness is found based on the correspondence between the actual film thickness and the strength of the paper base material, and the allowable length error range is determined based on the material strength.

[0131] Cumulative length difference = |unwinding speed - traction speed| × remaining unwinding time × traction speed;

[0132] When the cumulative length difference is greater than or equal to the first standard value, it is predicted that the cumulative length will cause the tension change to exceed the safe range of the current lower film strength or the current upper film strength, and the unwinding speed of the corresponding unwinding roller is corrected.

[0133] In practice, the unwinding speed is controlled by a combination of speed and torque, and the unwinding speed is increased in real time according to the ratio of the cumulative length difference to the second standard value.

[0134] When the cumulative length difference is less than or equal to the second standard value, the tension change caused by the cumulative predicted length will not exceed the safe range of the current lower membrane strength or the current upper membrane strength.

[0135] When the cumulative length difference is less than the first standard value but greater than the second standard value, analyze the impact of the corrective tension change on the cold stamping of the upper film and the heat sealing of the upper and lower films.

[0136] Wherein, the critical matching value is 1%, the first standard value is 0.05m, and the second standard value is 0.01m;

[0137] Specifically, the remaining unwinding time = remaining film roll length / traction speed, and the remaining film roll length = π × (film roll diameter) 2 - Roll diameter at the end of unwinding 2 () ÷ 4 times the actual thickness.

[0138] Specifically, as the film roll diameter decreases, the speed ω of the unwinding roller increases. However, if the initial speed matching is poor, the length difference L will continue to accumulate, leading to either film looseness or excessive tightness. The length of the lower film between the unwinding roller and the traction roller will continuously increase, resulting in greater and greater tension on the lower film. This method first determines the matching degree between the unwinding speed and the traction speed by using the speed matching value to determine whether to adjust the unwinding speed of the unwinding roller. At the same time, based on whether the predicted cumulative length difference will exceed the corresponding error allowable range, if it is confirmed that the cumulative length difference will exceed the corresponding error allowable range, the unwinding speed of the corresponding unwinding roller is corrected. This ensures the linear speed matching accuracy of the upper and lower film rolls in blister production, avoiding material failure or process failure caused by cumulative length errors.

[0139] In this embodiment, the lower film needs to be cold-pressed before heat sealing, and the upper film needs to be sprayed with several annular adhesive layers before heat sealing.

[0140] The process of analyzing and correcting the effects of tension changes on the cold stamping of the upper film and the heat sealing of the upper and lower films includes:

[0141] The actual tension of the lower film is detected, and the degree of decrease in the ability to undergo subsequent plastic deformation is predicted by combining the thickness change of the lower film paper base.

[0142] Calculate the consumption elongation rate, the consumption elongation rate = In the formula, T is the actual tension, E is the elastic modulus, A is the cross-sectional area of ​​the lower membrane, t is the actual thickness, α and n are the material hardening coefficient and exponent, Ty is the tension threshold corresponding to the yield strength, and Tu is the tension corresponding to the ultimate tensile strength;

[0143] During implementation, the prepared lower membrane was experimentally fitted, with α=0.5, n=1.5, and Ty and Tu being experimental calibration values;

[0144] When the consumption elongation is less than or equal to the critical elongation, the predicted decrease in the plastic deformation capacity of the lower film under the current actual tension does not exceed the normal range.

[0145] When the consumption elongation rate is greater than the critical elongation rate, the predicted decrease in the plastic deformation capacity of the lower film under the current actual tension exceeds the normal range. Stamping according to the determined target stamping pressure and target stamping speed will cause the blister to fail to meet the requirements.

[0146] When the decrease is within the normal range, increase the target stamping force according to the ratio of the total elongation of the material to (1 - the consumed elongation), and decrease the target stamping speed according to the change of the target stamping force.

[0147] When the descent exceeds the normal range, the judgment criteria for the change in the pullback tension exceeding the safety range of the upper and lower films are applied, and the unwinding speed of the unwinding roller is adjusted accordingly.

[0148] Specifically, the first standard value is reduced based on the ratio of consumption elongation to total material elongation;

[0149] Among them, the critical elongation rate is the total elongation of the material at 4%, and the elastic modulus, the cross-sectional area of ​​the lower film, and the total elongation of the material are the experimental test values ​​after the lower film is prepared.

[0150] Specifically, the thickness variation of the paper base of the lower film affects the elastic modulus. Greater thickness requires higher stamping pressure but reduces elongation. Furthermore, under the same tension, greater thickness results in a greater decrease in plastic deformation capacity and a lower tension tolerance. This invention divides the length variation of the lower film into an elastic deformation portion (linear term in the formula) and a plastic deformation portion (non-linear term in the formula). Based on the principle that elastic deformation is recoverable and plastic deformation is irrecoverable, the remaining elongation is calculated according to the actual tension borne by the lower film to quantify the severity of the decrease in plastic deformation capacity. When the decrease is not severe, the initial stamping speed is reduced to decrease dynamic stress impact. When the decrease is severe (tension approaches the tension threshold corresponding to the yield strength), it reflects an error in the current safe range of lower film strength, making it unsafe to protect the lower film when there is length accumulation between the film roll and the traction roller. By changing the judgment criteria, the safe range is corrected, increasing the accuracy and adaptability of judging and optimizing the lower film conveying situation before cold pressing.

[0151] The process of determining the impact of corrective tension changes on the cold stamping of the upper film and the heat sealing of the upper and lower films also includes:

[0152] Based on the several blister packs (the blister edge sealing area of ​​the lower film) generated after cold stamping and the several annular adhesive layers (the heat-sealing area of ​​the upper film) after the hot-seal adhesive is applied, the alignment deviation of the upper and lower films within a fixed time before the blister edge sealing area and the heat-sealing area move to the hot press plate of the hot stamping is predicted and analyzed.

[0153] Several annular adhesive layers (the heat-sealing area of ​​the upper film) and several blister packs (the sealing area at the edge of the blister packs of the lower film) need to be aligned;

[0154] The encoder installed on the traction roller detects the conveying length of the upper and lower films in real time after cold stamping and heat sealing coating, and calculates the coverage deviation value of the upper and lower film conveying lengths.

[0155] The coverage deviation value = |upper film conveying length - lower film conveying length|. When the coverage deviation value is less than or equal to the deviation evaluation value, it is determined that the alignment deviation of the upper and lower films is within the normal range, and the deviation trend of the heat sealant area and the blister edge sealing area is determined.

[0156] Specifically, the deviation trend is the ratio of the current coverage deviation value to the historical coverage deviation value. When the deviation trend is greater than one, it is determined that the deviation trend is increasing, and the critical matching value is reduced according to the coverage deviation value.

[0157] When the coverage deviation value is greater than the deviation evaluation value, it is determined that there is an alignment deviation between the upper and lower films, and the defect points are marked.

[0158] Specifically, when there is an alignment deviation between the upper and lower films, the unwinding speed of the upper film roll is reduced or increased when the upper film conveying length is greater than or less than the lower film conveying length, based on the ratio of the coverage deviation value to the fixed duration.

[0159] During implementation, after marking the defect locations, the subsequent slitting device automatically rejects blister packs with alignment deviations by skipping a single slitting sequence for a fixed duration.

[0160] The deviation evaluation value is 0.3 mm.

[0161] Specifically, since both the upper and lower films may have accumulated lengths, the difference in the degree of accumulated length can easily lead to deviations in heat sealing. Furthermore, it is known that the upper and lower films of paper-based blister sheets exhibit recoverable elastic deformation. If the impact of accumulated length on deviation is detected before cold stamping and heat sealing adhesive coating, errors due to elastic deformation can occur, leading to misjudgments. This method improves the accuracy of alignment deviation detection by separately detecting the conveying lengths of the upper and lower films after cold stamping and heat sealing adhesive coating. Simultaneously, it reflects whether tension changes and accumulated length lead to deviations based on the conveying lengths of the upper and lower films. Combining the deviation level and trend, it determines whether to mark defect locations. Based on the deviation trend, it adjusts the speed matching criteria and the unwinding speed of the upper film roll according to the coverage deviation value, thereby reducing the degree of accumulated length difference between the upper and lower films. By discussing the impact of accumulated lengths in both upper and lower films, it examines whether it causes excessive deviations between the blister edge sealing area of ​​the lower film and the heat sealing area of ​​the upper film, thus increasing adaptability to different deviation situations and the flexibility of heat sealing the upper and lower films of the packaging sheet.

[0162] An environmentally friendly, high-barrier paper-based blister packaging sheet, comprising:

[0163] The upper film is a paper-based composite layered structure, which consists of a composite paper base layer and a heat-sealable adhesive area, wherein the heat-sealable adhesive area includes several annular adhesive layers.

[0164] The lower film is a paper-based composite layered structure. The composite paper base layer of the lower film is stamped with several blister packs, which are distributed in an alternating manner. The thickness of the paper base layer of the lower film is greater than that of the paper base layer of the upper film.

[0165] The composite paper base layer comprises, from top to bottom, a varnish layer 101, an ink layer 102, a base coating layer 103, a paper base layer 104, a base coating layer 103, and a plating layer 105.

[0166] Specifically, compared with traditional aluminum-plastic blister packaging, the blister packaging sheet of the present invention has a paper-based composite layered structure. In order to avoid tearing damage to the paper base layer of the lower film during cold stamping, the blister packs stamped during cold stamping are distributed in an interlaced manner in the composite paper base layer of the lower film.

[0167] The top film is a sealing and easy-to-peel material, and the weight parameter of the top film ranges from 30g to 100g / m³. 2 The lower membrane is a foam material, and its weight parameters range from 60g to 400g / m³. 2 ;

[0168] Material parameter range: upper film basis weight range is 30-100 g / m³, lower film basis weight range is 60-400 g / m³;

[0169] The barrier performance requirement for the prepared blister pack sheets is that the water vapor transmission rate is less than or equal to 2 g / (m²). 2 •24h), oxygen permeability less than or equal to 2cm 3 / (m 2 ·24h·0.1MPa).

[0170] Varnish: It protects the ink and also has waterproof, moisture-proof, and oil-proof functions.

[0171] Ink: Used for text and patterns, 0-5g / m2, printing can be selected as needed;

[0172] Paper: It serves as the substrate for printing, and is a carrier for inks, primers, etc. It is generally 30g-400g / m2 thick.

[0173] Material selection requirements:

[0174] Since the top film does not require stamping, there are no relevant mechanical property requirements.

[0175] The lower film paper, due to its stamping process, has specific mechanical property requirements. These requirements are shown in the table below.

[0176]

[0177] Table 2 Performance Requirements of Lower Film Paper

[0178] Primer: Enhances coating adhesion. Fills paper pores, improving paper barrier properties.

[0179] Polyvinyl alcohol (PVA) coating is generally used as a base coat. After coating, the paper material fills the pores and improves the paper's barrier properties. PVA has high oxygen barrier properties, and after priming, it also enhances the adhesion of the coating process.

[0180] The application rate of the primer coating is 3-10 g / m² / layer;

[0181] Coating: Barrier against oxygen and water vapor; generally, aluminum oxide is used for vacuum deposition to improve the material's barrier properties (including barrier against oxygen and water vapor).

[0182] Heat-sealing adhesive: Used for heat sealing, it offers good airtightness and is easy to peel off. The application rate of heat-sealing adhesive is 5-10 g / m². 2 .

[0183] Specifically, most pharmaceutical / food blister packaging currently on the market is aluminum-plastic blister packaging. This is inconvenient to recycle and environmentally unfriendly. The product of this invention is a recyclable, environmentally friendly, high-barrier paper-based blister packaging material. The prepared blister packaging sheet is a single paper-based material with high barrier properties, heat-sealing performance, and is degradable, recyclable, and reusable. It can replace aluminum-plastic blister packaging as a recyclable and environmentally friendly alternative. It helps reduce the consumption of non-renewable resources by packaging materials, increases the interlayer bonding of paper through a base coating, and has minimal environmental pollution.

[0184] The technical solution of the present invention has been described above with reference to the preferred embodiments shown in the accompanying drawings. However, it will be readily understood by those skilled in the art that the scope of protection of the present invention is obviously not limited to these specific embodiments. Without departing from the principles of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will all fall within the scope of protection of the present invention.

[0185] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the present invention by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. A method for preparing an environmentally friendly high-barrier paper-based blister packaging sheet, characterized in that, include: The upper and lower films of the paper-based blister packaging sheet are wound into upper film rolls and lower film rolls, respectively. The cold stamping target parameters for cold stamping the lower film into bubbles are determined based on the differences in the layered structure of the lower film and the changes in the blister depth requirements. The determination coefficient of the cold stamping target parameters is adjusted according to the blister type and blister area variation to determine the criteria for subsequent consumption elongation and the amount of coating applied to the heat-sealing area of ​​the upper film. The matching degree between the unwinding speed and the traction speed is determined based on the matching values ​​of the rotational speeds of the unwinding roller and the traction roller, and it is determined whether to adjust the unwinding speed and predict the cumulative length difference within the unwinding time. Based on the prediction that the cumulative length difference exceeds the allowable range of the corresponding film roll strength error, confirm the impact of the tension change on the cold stamping of the lower film and the heat sealing of the upper and lower films, or, based on the prediction that the cumulative length difference does not exceed the allowable range of the corresponding film roll strength error, adjust the corresponding unwinding speed. The consumption elongation rate is calculated based on the actual thickness of the lower film and the actual tension change. The degree of decrease in the plastic deformation capacity of the lower film is predicted. If it does not exceed the normal range, the cold stamping target parameters are adjusted. If it exceeds the normal range, the cumulative length difference is adjusted back to the judgment standard that exceeds the corresponding allowable range of film roll strength error.

2. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 1, characterized in that, The differences in the lower film layer structure include differences in actual thickness parameters and differences in material yield strength. The cold stamping target parameters are the target stamping force and the target stamping speed.

3. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 2, characterized in that, The process of adjusting based on changes in blister type and blister area includes: When the blister type changes, the target stamping force is reduced by decreasing the safety factor, and the target stamping speed is reduced by decreasing the reference speed. When the area of ​​a single blister increases, the critical elongation is reduced according to the increase in blister area, and the amount of several annular adhesive layers is increased according to the increase in blister area. When the area of ​​a single blister becomes smaller, the critical elongation is increased according to the magnitude of the decrease in blister area, and the amount of several ring-shaped adhesive layers is reduced according to the magnitude of the decrease in blister area.

4. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 3, characterized in that, The process of determining the matching degree between the unwinding speed and the traction speed includes: When the rotational speed matching value is less than or equal to the critical matching value, it is determined that the unwinding speed and traction speed are at the first matching degree, and it is predicted whether the cumulative length difference will exceed the allowable range of the corresponding film roll strength error before the corresponding film roll is unwound under the current rotational speed difference matching degree. When the rotational speed matching value is greater than the critical matching value, it is determined that the unwinding speed and the traction speed are in the second matching degree, and the unwinding speed of the unwinding roller is adjusted according to the speed difference between the unwinding speed and the traction speed.

5. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 4, characterized in that, Calculate the cumulative length difference; When the cumulative length difference is greater than or equal to the first standard value, it is predicted that the cumulative length will cause the tension change to exceed the corresponding safe range of film roll strength, and the unwinding speed of the corresponding unwinding roller is corrected. When the cumulative length difference is less than the first standard value but greater than the second standard value, the effect of the corrected tension change on the cold stamping of the upper film and the heat sealing of the upper and lower films is confirmed.

6. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 5, characterized in that, The process of confirming the impact of corrective tension changes on the cold stamping of the upper film and the heat sealing of the upper and lower films includes: The actual tension of the lower membrane is detected and the consumption elongation rate is calculated in combination with the material parameters of the lower membrane. When the consumption elongation rate is less than or equal to the critical elongation rate, it is predicted that the decrease in the plastic deformation capacity of the lower membrane under the current actual tension is not beyond the normal range. When the consumption elongation rate is greater than the critical elongation rate, the predicted decrease in the plastic deformation capacity of the lower film under the current actual tension exceeds the normal range. Stamping according to the determined target stamping pressure and target stamping speed will cause the blister to fail to meet the requirements.

7. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 6, characterized in that, When the decrease is within the normal range, increase the target stamping force according to the total elongation of the material and the elongation consumed, and decrease the target stamping speed according to the change of the target stamping force. When the decline exceeds the normal range, the first standard value is reduced based on the ratio of the consumed elongation to the total elongation of the material, and the unwinding speed of the unwinding roll is corrected.

8. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 1, characterized in that, The process of confirming the impact of corrective tension changes on the cold stamping of the upper film and the heat sealing of the upper and lower films also includes: Calculate the coverage deviation value by obtaining the conveying length of the upper and lower films after cold stamping and heat-sealing adhesive coating, and determine the degree of alignment deviation between the blister edge sealing area and the heat-sealing adhesive area. The degree of alignment deviation is used to determine the deviation trend of the heat-sealing adhesive area and the sealing area of ​​the blister edge. The matching degree is adjusted according to the judgment criteria, or the defect points are marked to adjust the slitting sequence and the unwinding speed of the upper film roll.

9. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 8, characterized in that, The conveying lengths of the upper and lower films after cold stamping and heat-sealing are detected in real time, and the coverage deviation values ​​of the upper and lower film conveying lengths are calculated. When the coverage deviation value is less than or equal to the deviation evaluation value, it is determined that the alignment deviation of the upper and lower films is within the normal range, and the deviation trend of the heat-sealing adhesive area and the blister edge sealing area is determined. When the coverage deviation value is greater than the deviation evaluation value, it is determined that there is an alignment deviation between the upper and lower films, and the defect points are marked.

10. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 9, characterized in that, When there is an alignment deviation between the upper and lower films, the unwinding speed of the upper film roll is reduced or increased when the upper film conveying length is greater than or less than the lower film conveying length, based on the ratio of the coverage deviation value to the fixed duration. After marking the defect locations, the subsequent slitting device stops slitting for a fixed duration by skipping a single slitting sequence and then skipping a single packaging piece to remove blister packs with alignment deviations.

11. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 1, characterized in that, The production process of the upper and lower films is as follows: the coating liquid is applied to both sides of the paper base layer by roller coating or dip coating, and the coating is applied to both sides of the coated paper base layer. Depending on the requirements, it is determined whether to print varnish on the outside of the upper film and then roll it up to prepare the upper film roll or the lower film roll. The upper film is cold-stamped according to the target parameters of cold stamping, and the lower film is coated with a heat-sealing adhesive layer. Then, they are assembled into blister packaging sheets by hot pressing.

12. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 1, characterized in that, The control parameters for the primer include the material movement speed and drying temperature; The moving speed is less than or equal to 200 m / min, and the drying temperature is divided into three steps: the first step is 50-80℃, the second step is 70-100℃, and the third step is 90-120℃. The coating amount of the primer is 3-10 g / m². 2 / Single-sided.

13. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 1, characterized in that, The coating of the upper and lower films is vacuum-plated aluminum oxide. When printing on the upper or lower film, the printing speed is ≤350m / min, and the drying temperature after printing is 40-80℃.

14. The method for preparing the environmentally friendly high-barrier paper-based blister packaging sheet according to claim 1, characterized in that, The control parameters for applying the adhesive are the same as those for the primer. The application rate of the heat-sealing adhesive is 5-10 g / m². 2 .

15. An environmentally friendly high-barrier paper-based blister packaging sheet prepared using the method described in claims 1-14, characterized in that, include: The upper film is a paper-based composite layered structure, which consists of a composite paper base layer and a heat-sealable adhesive area, wherein the heat-sealable adhesive area includes several annular adhesive layers. The lower film is a paper-based composite layered structure. The composite paper base layer of the lower film is stamped with several blister packs, which are distributed in an alternating manner. The thickness of the paper base layer of the lower film is greater than that of the paper base layer of the upper film. The composite paper base layer comprises, from top to bottom, a varnish layer, an ink layer, a base coating layer, a paper base layer, a base coating layer, and a plating layer.

16. The environmentally friendly high-barrier paper-based blister packaging sheet according to claim 15, characterized in that, The weight parameters of the upper membrane range from 30g to 100g / m³. 2 The weight parameters of the lower membrane range from 60g to 400g / m³. 2 ; The barrier performance requirement for the prepared blister pack sheets is that the water vapor transmission rate is less than or equal to 2 g / (m²). 2 •24h), oxygen permeability less than or equal to 2cm 3 / (m 2 ·24h·0.1MPa).

17. The environmentally friendly high-barrier paper-based blister packaging sheet according to claim 15, characterized in that, Polyvinyl alcohol coating is used as the primer, with a coating amount of 3-10 g / m². 2 / layer; The coating uses aluminum oxide, and the heat-sealing adhesive has a coating weight of 5-10 g / m². 2 .

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