Diet management system and method for type 2 diabetes mellitus by combining food failure with ketogenic diet

Abstract

The invention belongs to the field of diet management, and particularly discloses a diet management system and a diet management method for type 2 diabetes mellitus through combination of food failure and ketogenesis, and the system comprises an applicable population screening module which is configured to lock patients based on biochemical indexes; the blood ketone dynamic monitoring module is configured to detect a blood ketone value in real time through a micro-fluidic chip sensor; the nutrition execution module is configured to output the following stage schemes: a feed-off period scheme; a ketogenic stage scheme; a transitional period scheme; according to the invention, through the staged management of the food failure combined ketogenic diet, in combination with the precise screening of suitable people, the dynamic monitoring of blood ketogen and the scientific configuration of a nutrition scheme, the blood glucose index of the type 2 diabetes mellitus patient can be effectively improved, and at the same time, by supplementing electrolyte, compound nutrients, antioxidants and the like, the intestinal health is maintained, the mitochondrial function is improved, and the blood uric acid is regulated and controlled, so that the health of the type 2 diabetes mellitus patient is improved. And after the HbA1c reaches the standard, the patient is assisted to smoothly transit to low-sugar diet, so that scientific management and control on the type 2 diabetes mellitus are realized.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of diet management, and particularly relates to a fasting combined with ketogenic diet management system and method for type 2 diabetes. BACKGROUND

[0002] With the development of social economy, the proportion of carbohydrates such as starch and refined sugar in the modern diet structure is too high, which causes the body to be in a "high sugar" state for a long time, induces mitochondrial oxidative damage, and further induces chronic diseases such as obesity, metabolic disorders, and immune function disorders. Although the low glycemic index diet advocated by the current mainstream medicine reduces the proportion of carbohydrates to 45-55%, glucose is still the main energy source for cells, and it is difficult to reverse the damage of chronic diseases that have already occurred, and even may continue to cause damage.

[0003] The energy sources of human cells include glucose produced by carbohydrate metabolism and ketone bodies produced by fat metabolism. When the intake of carbohydrates is strictly limited (such as fasting and ketogenic diet) and the intake of fat is increased, the body can switch to a "ketogenic state" with ketone bodies as the main energy source. Ketogenic diet has a long history, and the diet of human ancestors in the hunting era was low in sugar and even ketogenic. Modern humans still have the genetic basis of ketogenic metabolism, that is, the liver can metabolize fat into ketone bodies for energy through built-in programs. However, there is a lack of precise and periodic fasting-ketogenic combined management scheme for type 2 diabetes patients in the prior art, which is difficult to balance safety and stability of therapeutic effect. SUMMARY

[0004] The purpose of the present application is to provide a fasting combined with ketogenic diet management system and method for type 2 diabetes, which switches the energy source of the body (from glucose to ketone bodies), improves mitochondrial function, reduces insulin resistance, reverses type 2 diabetes and related metabolic abnormalities, and at the same time ensures safety, to solve the problems raised in the background art.

[0005] To achieve the above purpose, the present application provides the following technical scheme:

[0006] A fasting combined with ketogenic diet management system for type 2 diabetes, comprising:

[0007] A suitable population screening module is configured to lock patients based on biochemical indicators, and the locking conditions include:

[0008] Age 18-65 years old, BMI>24kg / m 2 , fasting insulin>5mIU / ml, normal liver function and no complications of diabetes, used to exclude patients with diabetic nephropathy stage V, diabetic foot ulcer with infection, and proliferative diabetic retinopathy;

[0009] Blood ketone dynamic monitoring module: configured to detect blood ketone value in real time through microfluidic chip sensor (detection range 0.1-20 mmol / L, response time <30 seconds), and execute:

[0010] When blood ketone value <0.5 mmol / L, generate diet adjustment instruction with protein intake ≤20% of total calories;

[0011] When blood ketone value >3 mmol / L, activate basic electrolyte sustained-release capsule release protocol (each contains potassium 300 mg, magnesium 150 mg, sodium bicarbonate 200 mg, release 2-4 capsules per day);

[0012] Nutrition execution module: configured to output the following phased scheme:

[0013] Fasting period scheme: 1-2 times per month, 1-2 days each time, the first meal after fasting is 100 g of pickles and 2 pieces of coconut oil fried eggs;

[0014] Ketogenic period scheme: intake of fat 70%, protein 25%, and carbohydrate 5% of total calories;

[0015] Transition period scheme: when glycosylated hemoglobin HbA1c ≤6.5% for 30 days, switch to low-carbohydrate diet with carbohydrate accounting for 30%, which is provided by protein-derived conversion, specifically: amino acids formed after protein decomposition, some of which have "gluconeogenic ability" and can be converted into glucose in the liver or microorganisms through a series of enzymatic reactions. Such amino acids are called "glycogenic amino acids" or "gluconeogenic amino acids".

[0016] Preferably, the fasting period scheme includes synchronous supplementation:

[0017] Electrolyte composition: potassium ≥2000 mg / day, sodium <2000 mg / day, magnesium ≥300 mg / day;

[0018] Complex nutrients: vitamin D3 2000 IU, vitamin K2 200 μg, fish oil 1 g, wherein the total content of EPA and DHA ≥80%.

[0019] Preferably, the ketogenic period scheme contains:

[0020] Antioxidant combination: natural vitamin C 500-1000 mg, lipoic acid 600-1200 mg;

[0021] Mitochondrial activator: L-carnitine 1-3 g, sodium salicylate 100 mg;

[0022] Intestinal homeostasis formula: Lactobacillus plantarum ≥10^9 CFU, water-soluble cellulose 5-10 g, γ-glutamine 3-5 g.

[0023] Lactobacillus plantarum isolated from Sichuan pickled vegetable is inoculated into pickled vegetable juice with a salinity of 6% and fermented at 37°C for 48 hours, and 10 mL of the fermented liquid is taken orally (bacterial content ≥ 10^9 CFU).

[0024] Preferably, in the ketogenic period scheme:

[0025] The fat source is at least one of anhydrous butter, coconut oil, olive oil, bitter tea oil, and animal fat, avoiding omega-6 and deep-processed oxidized oil;

[0026] The protein source is at least one of poultry eggs, animal meat, and plant protein;

[0027] Poultry eggs and animal meat are preferred, and plant protein is less preferred, with milk being excluded.

[0028] The carbohydrate source is at least one of coconut powder, almond powder, psyllium fiber powder, konjac rice, konjac noodles, erythritol, and stevioside.

[0029] Flour is replaced by coconut powder, almond powder, and psyllium fiber powder, and rice and noodles are replaced by konjac rice and konjac noodles, and sugar is replaced by erythritol and stevioside.

[0030] Konjac powder is mixed with oat beta-glucan at a ratio of 7:3, and konjac rice with a glycemic index <15 is produced by double-screw extrusion, replacing traditional staple foods.

[0031] All the above-mentioned carbohydrate sources are non-starch, and this principle is continued in the transition period to ensure consistency in the carbohydrate source from the ketogenic period to the low-carbohydrate period, avoiding the interference of starchy food materials on metabolism.

[0032] Preferably, the nutritional execution module outputs the following for the out-of-diet scenario:

[0033] Fat composition: olive oil and butter are mixed at a mass ratio of 1:1, and 20-30 g is ingested per meal;

[0034] Collaboration instructions: fatty meat or fish, bulletproof coffee, or bulletproof cocoa.

[0035] A method for managing type 2 diabetes by intermittent fasting combined with a ketogenic diet, comprising:

[0036] S1, early intestinal pre-adaptation: 15 g of cabbage (water-soluble cellulose) and 10 g of glutamine (intestinal barrier repair agent) are supplemented daily for 2 weeks in advance, and the number of meals is reduced to 1-2 times per day;

[0037] S2, execute the fasting period:

[0038] Fasting for 1-2 days every 1-4 weeks;

[0039] Daily water intake ≥2000ml, synchronous supplementation of the electrolyte composition (potassium ≥2000mg / day, sodium <2000mg / day, magnesium ≥300mg / day) and complex nutrients (vitamin D3 2000 IU, vitamin K2 200μg, fish oil 1g, wherein EPA+DHA ≥80%);

[0040] Preferably 1-2 days, 1-2 times per month, if the body is combined with multiple metabolic diseases, fasting for 2 days, 1-2 times per 1-2 weeks

[0041] S3, execute the ketogenic period:

[0042] According to the scheme, the formula portion intake of calories is combined with the daily intake of ≥500g vegetables, including at least one of spinach, broccoli and lettuce, that is, 70% fat, 25% protein and 5% carbohydrate in the total heat intake;

[0043] Functional supplementation: antioxidant combination (natural vitamin C 500-1000mg, thioctic acid 600-1200mg), mitochondrial activator (L-carnitine 1-3g, sodium salicylate 100mg), intestinal homeostasis formula (plant lactobacillus ≥1×10 9 CFU, water-soluble cellulose 5-10g, γ-glutamine 3-5g).

[0044] S4, dynamic monitoring:

[0045] Blood ketone and blood glucose monitoring: fasting and 2 hours after meal twice a week to detect blood ketone (target 0.5-3mmol / L) and blood glucose (target ≤13.3mmol / L);

[0046] Blood uric acid regulation: detect once a month, when blood uric acid >480μmol / L, start alkali urine protocol (oral sodium bicarbonate tablets, 3 times a day, 0.5g each time).

[0047] When blood uric acid >480μmol / L:

[0048] Alkali urine: oral sodium bicarbonate tablets 0.5g tid;

[0049] Promote uric acid excretion: benzbromarone tablets 50mg qd (normal liver and kidney function).

[0050] Preferably, the protein intake is dynamically adjusted according to the following formula:

[0051]

[0052] Compared with the prior art, the beneficial effects of the present application are:

[0053] The present application can effectively improve the blood glucose index of type 2 diabetes patients through the phased management of fasting combined with ketogenic diet, combined with precise screening of suitable population, dynamic monitoring of blood ketones and scientific configuration of nutrition scheme, while through the supplement of electrolytes, complex nutrients, antioxidants and the like, maintaining intestinal health, improving mitochondrial function, regulating blood uric acid and the like, ensuring the safety and effectiveness of diet management, helping patients to smoothly transition to low-sugar diet after HbA1c target, and realizing scientific control of type 2 diabetes.

[0054] The present application can effectively improve the blood glucose index of type 2 diabetes patients through the phased management of fasting combined with ketogenic diet, combined with precise screening of suitable population, dynamic monitoring of blood ketones and scientific configuration of nutrition scheme, while through the supplement of electrolytes, complex nutrients, antioxidants and the like, maintaining intestinal health, improving mitochondrial function, regulating blood uric acid and the like, ensuring the safety and effectiveness of diet management, helping patients to smoothly transition to low-sugar diet after HbA1c target, and realizing scientific control of type 2 diabetes.

[0055] The present application can effectively improve the blood glucose index of type 2 diabetes patients through the phased management of fasting combined with ketogenic diet, combined with precise screening of suitable population, dynamic monitoring of blood ketones and scientific configuration of nutrition scheme, while through the supplement of electrolytes, complex nutrients, antioxidants and the like, maintaining intestinal health, improving mitochondrial function, regulating blood uric acid and the like, ensuring the safety and effectiveness of diet management, helping patients to smoothly transition to low-sugar diet after HbA1c target, and realizing scientific control of type 2 diabetes. DETAILED DESCRIPTION

[0056] In order to make the above-mentioned purposes, features and advantages of the present application more apparent and easy to understand, the specific embodiments of the present application are described in detail below.

[0057] In the following description, a large number of specific details are set forth in order to facilitate a thorough understanding of the present application, but the present application can also be implemented in other ways different from those described herein, and those skilled in the art can make similar generalizations without departing from the connotation of the present application, therefore the present application is not limited by the specific embodiments disclosed below.

[0058] Secondly, the "one embodiment" or "embodiment" referred to herein means that the specific features, structures or characteristics can be included in at least one implementation of the present application. "In one embodiment" appearing in different places in the specification does not mean the same embodiment, nor is it an embodiment that is separate or alternative to other embodiments.

[0059] Embodiment one: the present embodiment provides a fasting combined with ketogenic diet management system for type 2 diabetes.

[0060] Specific configuration and operation of system module

[0061] System hardware configuration:

[0062] Patient population screening module: Obtain patient biochemical data (age, BMI, fasting insulin, liver function, and complication diagnosis) by accessing the hospital LIS system, automatically match the screening conditions, and output "conformity / non-conformity" results;

[0063] Blood ketone dynamic monitoring module: Microfluidic blood ketone detection chip is used for fingertip blood sampling (5 μL) detection, and data is uploaded to the system terminal (mobile phone APP or computer client) in real time;

[0064] Nutrition execution module: The built-in algorithm calculates the total heat according to the patient's gender, age, and weight (1800-2000 kcal / day for women and 2000-2200 kcal / day for men), automatically allocates the proportion of each nutrient, and generates a recipe (including food weight and cooking method).

[0065] Embodiment two provides a fasting combined with ketogenic diet management method for type 2 diabetes.

[0066] Specific execution process of the method

[0067] Case parameters: male patient, 50 years old, 3 years of history of type 2 diabetes, meeting the screening conditions (age 50 years old, BMI 26 kg / m 2 , fasting insulin 6 mIU / ml, normal liver function, and no complications).

[0068] Step 1: Pre-intestinal pre-adaptation (2 weeks)

[0069] Daily supplementation: 15 g of water-soluble cellulose (divided into two times in the morning and evening, and taken with warm water), and 10 g of γ-glutamine (taken after breakfast);

[0070] Meal adjustment: change from 3 meals (morning, noon, and evening) to 2 meals (breakfast at 7:00 and dinner at 18:00), and avoid snacks.

[0071] Step 2: Fasting period execution (2 times a month, each time for 1 day)

[0072] Fasting day process:

[0073] 00:00-24:00: stop eating, only supplement water (warm water or light tea, total amount 2500 ml, drink 8 times);

[0074] Electrolyte supplementation: take 1 piece of electrolyte effervescent tablet (containing 1000 mg of potassium, 500 mg of sodium, and 150 mg of magnesium) at 9:00 am, and repeat at 15:00;

[0075] Complex nutrient supplementation: Vitamin D3 capsule (2000 IU) + Vitamin K2 tablet (200 μg) at 10:00 in the morning, fish oil capsule 1 g (containing EPA 400 mg, DHA 400 mg) at dinner time (18:00);

[0076] First meal after the end of the fast: pickled vegetables 100 g (self-made, salinity 5%, fermented for 7 days, containing lactic acid bacteria 1 x 10 8 CFU / g) + coconut oil fried eggs 2 (coconut oil 10 g, frying time 2 min / egg).

[0077] Step 3: Perform the ketogenic phase (for 3 months)

[0078] Total daily calories for the patient: 2000 kcal (calculated according to body weight 70 kg), nutritional ratio: fat 70% (155.6 g), protein 25% (125 g), carbohydrate 5% (25 g).

[0079] Daily diet specific composition:

[0080] Fat source:

[0081] Breakfast: bulletproof coffee (black coffee 200 ml + anhydrous butter 15 g + coconut oil 10 g);

[0082] Lunch: olive oil 10 g (fry salmon) + pork fat 30 g;

[0083] Dinner: bitter tea oil 10 g (stir-fried spinach) + beef tallow 20 g (fry eggs);

[0084] Snack: coconut oil 10 g (added to sugar-free yogurt).

[0085] Protein source:

[0086] Breakfast: 2 eggs (protein 12 g);

[0087] Lunch: salmon 150 g (protein 30 g);

[0088] Dinner: lean beef 100 g (protein 20 g) + almonds 30 g (protein 10 g);

[0089] Snack: chicken breast 50 g (protein 10 g).

[0090] Carbohydrate source:

[0091] Konjac rice 100 g (carbohydrate 5 g), almond powder 20 g (carbohydrate 3 g), psyllium fiber powder 5 g (carbohydrate 2 g), erythritol 5 g (for flavored coffee).

[0092] Vegetable intake:

[0093] Lunch: Broccoli 200g;

[0094] Dinner: Spinach 200g + Lettuce 100g (total 500g).

[0095] Functional supplements:

[0096] Morning: Natural Vitamin C 500mg, L-Carnitine 1g;

[0097] After lunch: Lipoic acid 600mg, Sodium Salicylate 100mg;

[0098] After dinner: Lactobacillus plantarum capsules (containing 1x10 9 CFU), water-soluble cellulose 5g, γ-glutamine 3g.

[0099] Out-of-home meal coping:

[0100] Self-prepared mixed fat (olive oil 15g + butter 15g) drizzled on restaurant vegetable salad (lettuce 200g);

[0101] Main meal choice: Roast bacon 100g (fat 50g, protein 20g) + Bulletproof cocoa (cocoa powder 10g + coconut oil 10g).

[0102] Step 4: Dynamic monitoring and adjustment

[0103] Blood ketone and blood glucose monitoring:

[0104] Weekly Monday and Thursday morning fasting tests: Blood ketones 1.8 mmol / L (within target range), blood glucose 6.5 mmol / L;

[0105] 2-hour postprandial test: Blood ketones 2.2 mmol / L, blood glucose 8.0 mmol / L (both meet standards).

[0106] Abnormal blood ketone value handling:

[0107] 4th week blood ketone test 0.4 mmol / L (<0.5 mmol / L), system generates instructions: reduce protein intake from 25% to 20% (100g / day), reduce chicken breast by 50g, increase pork belly by 20g; 3 days after adjustment, blood ketones rise to 1.2 mmol / L.

[0108] Blood uric acid monitoring:

[0109] 2nd month blood uric acid test 490 μmol / L (>480 μmol / L), initiate alkaline urine protocol: oral sodium bicarbonate tablets, 3 times a day, 0.5g each, 1 week later blood uric acid drops to 450 μmol / L.

[0110] Step 5: Transition phase (4th month)

[0111] Patient 3 months after the end of the ketosis phase, HbA1 c was detected to be 6.3% (≤6.5%, sustained for 30 days), and the system automatically switched to the transition phase program: carbohydrates 30% (150g), fat 50% (111g), protein 20% (100g), and the specific diet was:

[0112] Konjac rice 150g (carbohydrates 7.5g), almond powder 30g (carbohydrates 4.5g), psyllium fiber powder 10g (carbohydrates 4g), and the rest of the carbohydrates were supplemented to 150g through the probiotic conversion of protein (chicken breast, lean beef, etc.); reduce 20g of pork fat, increase 50g of chicken breast (increase protein intake to support carbohydrate conversion).

[0113] Example effect verification

[0114] After the patient performed the system and method of the present application for 3 months, the indicators changed as follows:

[0115] Body weight: from 70 kg to 63 kg (decrease of 10%);

[0116] Fasting insulin: from 15 mIU / ml to 8 mIU / ml (insulin resistance reduced);

[0117] Glycated hemoglobin (HbA1 c): from 7.5% to 6.3%;

[0118] Blood ketones: stable at 1.5-2.5 mmol / L (within the target range);

[0119] Side effects: no "ketone flu", electrolyte imbalance, and gout attacks, and the incidence of intestinal discomfort was 0.

[0120] It is important to note that the construction and arrangement of the application shown in the various exemplary embodiments is illustrative only. Although only a few embodiments have been described in detail in this disclosure, those skilled in the art who review the present disclosure will readily appreciate that many modifications are possible (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters, mounting arrangements, use of materials, colors, orientations, etc.) without materially departing from the novel teachings and advantages of the subject matter described herein. For example, elements shown as integrally formed can be constructed of multiple parts or elements, the position of elements can be reversed or otherwise varied, and the nature or number of elements or positions can be altered or varied. Thus, the foregoing description is by way of example only, and is not intended to be limiting. The application is limited only as defined in the following claims and equivalents thereto. The sequence of any process or method steps, or the order in which they are carried out, can be altered or re-ordered without departing from the scope of the application. Any "articles of manufacture" or "manufacturing" as described herein are intended to encompass structures constructed of a multitude of different physical elements or components. In the claims, any means-plus-function clause is intended to cover the structures described herein as performing the recited function and also cover structures yet to be invented which perform the recited function but operate in a different manner. Other substitutions, modifications, changes and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the application as expressed in the appended claims.

[0121] Also, to provide a concise description of the exemplary embodiments, not all features of an actual implementation can be described (that is, not all implementations can include all of the features described or optional implementations can include only a subset of the features described).

[0122] It should be appreciated that in the development of any actual implementation, as in any engineering or design project, numerous implementation-specific decisions can be made. Such development efforts might be complex and time-consuming, but would nevertheless be a routine undertaking for those of ordinary skill in the art having the benefit of this disclosure.

[0123] It should be noted that the above-mentioned embodiments are only used to illustrate the technical solutions of the present application but not to limit the present application, and although the present application is described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or equivalent replaced without departing from the spirit and scope of the present application, and all should be covered in the scope of the claims of the present application.

Claims

1. A fasting combined with ketogenic diet management system for type 2 diabetes, characterized in that, include: Applicable population screening module: Configured to identify patients based on biochemical indicators. The identification criteria include: Age 18-65 years, BMI > 24 kg / m² 2 Fasting insulin >5 mIU / ml, normal liver function, and no diabetic complications; Blood ketone dynamic monitoring module: configured to detect blood ketone levels in real time via a microfluidic chip sensor and perform the following: When the blood ketone level is <0.5 mmol / L, an instruction is generated for protein intake to be ≤20% of total calories; When blood ketone levels are >3 mmol / L, the alkaline electrolyte sustained-release capsule release protocol is activated; Nutrition execution module: Configured to output the following phased scheme: Fasting plan: 1-2 times per month, 1-2 days each time. The first meal after the fast ends is 100g of kimchi and 2 eggs fried in coconut oil. Ketogenic diet plan: Consume 70% fat, 25% protein, and 5% carbohydrates of total calories; Transitional plan: When HbA1c ≤ 6.5% for 30 consecutive days, switch to a low-sugar diet with 30% carbohydrates, provided by protein prebiotic conversion.

2. The fasting combined with ketogenic diet management system for type 2 diabetes according to claim 1, characterized in that, The fasting program includes simultaneous supplementation: Electrolyte composition: Potassium ≥ 2000 mg / day, Sodium < 2000 mg / day, Magnesium ≥ 300 mg / day; Complex nutrients: Vitamin D3 2000 IU, Vitamin K2 200 μg, fish oil 1g, of which the total content of EPA and DHA is ≥80%.

3. The fasting combined with ketogenic diet management system for type 2 diabetes according to claim 1, characterized in that, The ketogenic regimen includes: Antioxidant combination: 500-1000mg of natural vitamin C, 600-1200mg of alpha-lipoic acid; Mitochondrial activators: L-carnitine 1-3g, sodium salicylate 100mg; Intestinal stabilization formula: Lactobacillus plantarum ≥10^9 CFU, water-soluble cellulose 5-10g, γ-glutamylamine 3-5g.

4. The fasting combined with ketogenic diet management system for type 2 diabetes according to claim 1, characterized in that, In the aforementioned ketogenic diet regimen: The fat source is at least one of anhydrous butter, coconut oil, olive oil, camellia oil, and animal fats; The protein source is at least one of poultry eggs, animal meat, or plant protein; Carbohydrate sources include at least one of coconut powder, almond powder, psyllium husk fiber powder, konjac rice, konjac noodles, erythritol, and steviol glycosides.

5. A fasting combined with ketogenic diet management system for type 2 diabetes according to claim 1, characterized in that, The nutrition execution module outputs the following for dining out scenarios: Oil composition: Mix olive oil and butter in a 1:1 mass ratio, and consume 20-30g per meal; Pairing instructions: fatty meat or fish, bulletproof coffee or bulletproof cocoa.

6. A method for managing type 2 diabetes using a combination of fasting and a ketogenic diet, characterized in that, include: S1. Pre-intestinal preconditioning: Supplement with 15g of water-soluble fiber and 10g of glutamine daily for 2 weeks in advance, and reduce the number of meals to 1-2 times / day; S2, Fasting Period: Fast for 1-2 days every 1-4 weeks; Drink ≥2000ml of water daily, and supplement with the electrolyte composition and complex nutrients simultaneously; S3, Execute the ketogenic period: While consuming calories according to the formula and portion size set in the plan, you should also consume ≥500g of vegetables daily, including at least one of spinach, broccoli, and lettuce; S4. Dynamic Monitoring: Blood ketone and blood glucose monitoring: tested twice a week, once fasting and once 2 hours after a meal; Uric acid regulation: When uric acid > 480 μmol / L, the urine alkalization protocol is initiated.

7. A method for managing type 2 diabetes using a combination of fasting and ketogenic diet according to claim 6, characterized in that, The formula for dynamically adjusting protein intake is as follows:

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