Oil-controlling and acne-removing composition specially researched by men and application of oil-controlling and acne-removing composition

Abstract

The invention relates to an oil-controlling and acne-removing composition specially researched by men and application thereof, and the composition comprises the following components: rosewood seed extract, pseudoalteromonas fermentation product extract, amur corktree bark extract, cynara scolymus leaf extract and magnolia sieboldii extract. The weight ratio of the rosewood seed extract to the pseudoalteromonas fermentation product extract to the amur corktree bark extract to the cynara scolymus leaf extract to the magnolia sieboldii extract is (0.05-2): (0.5-2): (0.2-1): (0.2-5): (0.1-5). According to the oil-controlling and acne-removing composition disclosed by the invention, through the synergism of the five components, the acne problem of men can be relieved from multiple aspects of oil controlling, bacterium resisting, inflammation resisting, repairing, moisturizing and the like.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of oil-controlling and acne-removing cosmetics, in particular to an oil-controlling and acne-removing composition specially researched for men and application thereof. BACKGROUND

[0002] In recent years, the awareness of male skin care has gradually improved, but it still mainly focuses on cleansing products, and the importance of oil-controlling and acne-removing care is insufficient.

[0003] There are significant differences in physiological structure and microecological composition between male and female skin. Studies have shown that the average sebum secretion of men is 2 times higher than that of women, and the water loss is 25% higher than that of women. However, the current acne-removing products are mostly general formulas, which mainly work by reducing sebum secretion, inhibiting the excessive keratinization of hair follicle keratin layer, inhibiting the reproduction of Propionibacterium acnes in sebaceous glands, anti-inflammatory and regulating microecology, etc., and cannot be optimized for the higher sebum secretion level of men and the barrier damage caused by shaving.

[0004] Therefore, in addition to considering the oil-controlling and acne-removing effect, the oil-controlling and acne-removing products for men also need to consider the barrier damage caused by shaving and other operations. SUMMARY

[0005] The present application aims to overcome the deficiencies of the prior art and provide an oil-controlling and acne-removing composition specially researched for men and application thereof.

[0006] To achieve the above-mentioned purpose, the technical solution adopted by the present application is as follows:

[0007] In a first aspect, the present application provides an oil-controlling and acne-removing composition specially researched for men, which comprises the following components: B. sphaerocarpa seed extract, Pseudoalteromonas ferment extract, Phellodendron amurense bark extract, Cynara scolymus leaf extract and Magnolia sieboldii extract, and the weight ratio of the B. sphaerocarpa seed extract, Pseudoalteromonas ferment extract, Phellodendron amurense bark extract, Cynara scolymus leaf extract and Magnolia sieboldii extract is (0.05-2):(0.5-2):(0.2-1):(0.2-5):(0.1-5).

[0008] The effects of each component in the composition of the present application are as follows:

[0009] The B. sphaerocarpa seed extract can reduce the activity of sebaceous glands, achieve the purpose of controlling oil from the source by limiting the excessive production of lipids in the sebaceous glands; in addition, the B. sphaerocarpa seed extract can block the IGF-1 signaling pathway in keratinocytes, inhibit its binding with the receptor, and then inhibit the proliferation of sebaceous gland cells, reduce the activity of sebaceous glands, and reduce sebum secretion. In addition, the B. sphaerocarpa seed extract can also maintain skin moisture.

[0010] The Pseudoalteromonas ferment extract can reduce the content of melanocortin receptor 5 (MC5-R) associated with the differentiation of sebaceous gland cells, thereby reducing the accumulation of sebum lipids in the differentiated sebaceous gland cells and slowing down the maturation of the sebaceous gland cells.

[0011] The extract of Bupleurum chinense DC. has a significant bacteriostatic effect on Propionibacterium acnes, can reduce inflammation caused by acne, accelerate wound healing, and eliminate acne.

[0012] The active substances in the extract of Cynara scolymus L. can effectively inhibit the activation of NF-kB, thereby reducing inflammatory reactions, and most of the active substances such as polyphenols and ketones have strong antioxidant properties, can effectively scavenge free radicals, and reduce the damage to the skin caused by oxidative stress. In addition, the polyphenol active substance can also promote the synthesis of skin collagen, enhance the elasticity and firmness of the skin.

[0013] The extract of Magnolia sieboldii K.Koch contains rich moisturizing ingredients, can increase the moisture content of the skin, enhance the water retention capacity of the skin, and keep the skin moist.

[0014] Preferably, the weight ratio of the extract of Bixa orellana L. seeds, the extract of Pseudoalteromonas ferment, the extract of Bupleurum chinense DC., the extract of Cynara scolymus L. leaves, and the extract of Magnolia sieboldii K.Koch is (0.1-0.5) :(0.8-1.5) :(0.3-0.8) :(3-5) :(1-5).

[0015] Most preferably, the weight ratio of the extract of Bixa orellana L. seeds, the extract of Pseudoalteromonas ferment, the extract of Bupleurum chinense DC., the extract of Cynara scolymus L. leaves, and the extract of Magnolia sieboldii K.Koch is 0.2:1:0.5:2:2.

[0016] Preferably, the extract of Bixa orellana L. seeds is purchased from Xi'an Tiankang Biotechnology Co., Ltd.

[0017] Preferably, the extract of Pseudoalteromonas ferment is purchased from Lipotec Company.

[0018] Preferably, the extract of Bupleurum chinense DC. is purchased from Guangzhou Hekai Biotechnology Co., Ltd.

[0019] Preferably, the extract of Cynara scolymus L. leaves is purchased from Zhenghe (Guangzhou) Biotechnology Co., Ltd.

[0020] Preferably, the extract of Magnolia sieboldii K.Koch is purchased from Guangzhou Jinbaolai Biotechnology Co., Ltd.

[0021] In the second aspect, the application provides the use of the male-specific oil-controlling and acne-removing composition in the first aspect in the preparation of cosmetics.

[0022] Preferably, the cosmetic is one of a cosmetic water, an emulsion, a cream, a mask and a serum, and the added amount of the oil-control and acne-removing composition is 2-8% of the total weight of the cosmetic.

[0023] In a third aspect, the present application provides an oil-control and acne-removing emulsion, comprising the following raw materials by weight percentage: 2-8% of the oil-control and acne-removing composition for men in the first aspect, 4-8% of a humectant, 0.1-0.3% of a thickening agent, 0.03-0.1% of a chelating agent, 5-8% of an emulsifier, 0.5-2% of a preservative, 0.01-0.3% of a pH regulator, and the balance being deionized water.

[0024] Preferably, the humectant is at least one of allantoin, betaine, beta-glucan, trehalose, caprylyl glycol, dipropylene glycol, D-panthenol, sodium hyaluronate, 1,2-butanediol, glycerol, pullulan and ceramide.

[0025] Preferably, the thickening agent is at least one of xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyltaurate / VP copolymer and arthrobacter gum.

[0026] Preferably, the chelating agent is EDTA-2Na.

[0027] Preferably, the emulsifier is at least one of coco-caprylate / caprate, dimethicone, hydrogenated palm kernel oil, cetyl stearyl alcohol, polyglyceryl-6 diisostearate and polymethylsilsesquioxane.

[0028] Preferably, the preservative is at least one of 1,3-propanediol, 1,2-hexanediol and p-hydroxyacetophenone.

[0029] Preferably, the pH regulator is at least one of arginine, tromethamine and disodium EDTA.

[0030] In a fourth aspect, the present application provides a preparation method of the oil-control and acne-removing emulsion in the third aspect, comprising the following steps:

[0031] S1, mixing the humectant, the thickening agent, the chelating agent and the deionized water, homogenizing at 75-85°C to obtain an aqueous phase;

[0032] S2, homogenizing the emulsifier at 75-85°C to obtain an oil phase;

[0033] S3, stirring the aqueous phase and the oil phase uniformly, adding the preservative after the temperature is reduced to 55-65°C, stirring uniformly, adding the components in the oil-control and acne-removing composition for men after the temperature is reduced to 35-45°C, stirring uniformly, and finally adding the pH regulator to adjust the pH to obtain the oil-control and acne-removing emulsion.

[0034] Compared with the prior art, the application has the following beneficial effects:

[0035] The redwood seed extract and the pseudomonas alternaria fermentation product extract in the oil-controlling and acne-removing composition of the application have a synergistic effect, which can reduce the secretion of sebum from the aspects of inhibiting the proliferation of sebaceous gland cells and slowing down the maturation of sebaceous gland cells; the cinnamomum parvifolium bark extract can kill propionibacterium acnes, thereby eliminating the acne causes from the root, and the cynara scolymus leaf extract can rapidly inhibit the inflammatory reaction caused by bacteria by inhibiting the NF-kB pathway, and the two components can effectively prevent and resolve the red and swollen acne and avoid pigmentation and scar formation; the cynara scolymus leaf extract has an anti-inflammatory effect, and the polyphenols in the cynara scolymus leaf extract can promote the synthesis of collagen, thereby having a repairing effect, and the magnolia kobus extract has a strong moisturizing effect, which can enhance the water retention capacity of the skin and create a good hydration environment for repair, and the two components can synergistically enhance the repairing effect of the composition and relieve the barrier damage problem of men caused by shaving and the like. Therefore, the oil-controlling and acne-removing composition of the application can relieve the acne problem of men from multiple aspects such as oil control, antibiosis, anti-inflammation, repair and moisturization through the synergistic effect of the five components. DETAILED DESCRIPTION

[0036] In order to better illustrate the purposes, technical solutions and advantages of the application, the application will be further described below in combination with specific examples.

[0037] The raw materials used in the following examples and comparative examples are as follows:

[0038] Redwood seed extract: purchased from Xi'an Tiankang Biological Technology Co., Ltd.;

[0039] Pseudomonas alternaria fermentation product extract: purchased from Lipotec Company;

[0040] Cinnamomum parvifolium bark extract: purchased from Guangzhou Hegui Biological Technology Co., Ltd.;

[0041] Cynara scolymus leaf extract: purchased from Zhenghe (Guangzhou) Biological Technology Co., Ltd.;

[0042] Magnolia kobus extract: purchased from Guangzhou Jinbaolai Biological Technology Co., Ltd.

[0043] Other materials and reagents used in the examples can be obtained from commercial channels unless otherwise specified.

[0044] Examples 1-5 and Comparative Examples 1-5

[0045] The compositions of the oil-controlling and acne-removing compositions for men of Examples 1-5 and Comparative Examples 1-5 are shown in Table 1. The total mass fraction of each group of compositions is 100 parts.

[0046] Formulation of the oil-control and acne-removing composition for men in each group in Table 1

[0047]

[0048]

[0049] The method for preparing the oil-control and acne-removing composition for men in Examples 1-5 and Comparative Examples 1-5 comprises the following steps:

[0050] The ingredients in the formulation amount are stirred uniformly to obtain the composition.

[0051] Test Example 1: Inhibition of sebum synthesis experiment of the oil-control and acne-removing composition in each group

[0052] (1) Preparation of solution:

[0053] Preparation of test sample: 0.10 mL of the composition sample in Examples 1-5 and Comparative Examples 1-5 was taken respectively, and 0.90 mL of sodium acetate-free DMEM (Gibco, C11965500BT) culture solution was added to prepare a 10% concentration mother liquor;

[0054] Preparation of hydrocortisone solution: 0.01 g of hydrocortisone (Shanghai Yuan Ye Bio, S31360) was weighed and added to 1 mL of methanol to prepare a 10 mg / mL stock solution;

[0055] Preparation of isotretinoin solution: 0.01 g of isotretinoin (Shanghai Dibo Bio, H573005) was weighed and added to 1 mL of methanol to prepare a 10 mg / mL stock solution;

[0056] Culture solution: 10 mL of fetal bovine serum FBS (Macklin / McCline, F917980) was taken and added to 90 mL of DMEM culture solution to prepare a 10% FBS-containing sodium acetate-free DMEM culture medium;

[0057] Maintenance culture solution: 1 mL of fetal bovine serum FBS was taken and added to 99 mL of DMEM culture solution to prepare a 1% FBS-containing sodium acetate-free DMEM culture medium;

[0058] PBS buffer: purchased from Gibco, item number C10010500BT.

[0059] (2) Experimental grouping:

[0060] Negative control group (NT): maintenance culture solution;

[0061] Model group (M): maintenance culture solution + 10 ng / mL hydrocortisone;

[0062] Positive control group (PC): 0.01 mM isotretinoin + maintenance medium + 10 ng / mL hydrocortisone;

[0063] Sample group (TA): 0.001% sample + maintenance medium + 10 ng / mL hydrocortisone;

[0064] (3) Neutral lipid fluorescence quantitative experiment:

[0065] The cell line used was human sebaceous gland cell SZ95 (Shanghai Qingqi Biological, BFN60807569), with a passage number of 7, and the test conditions were: incubator temperature 37±1°C, humidity 90±5%, carbon dioxide 5±1%; the cell suspension was inoculated in a 96-well cell culture plate (black bottom transparent type), with a density of 1.0×10 4 cells / well, and 100 μL of culture medium was added to each well, and cultured for 18-24 h to adhere;

[0066] The supernatant was discarded, and the required components for the negative control group, positive control group, model group, and sample group were added according to the above experiment, with 3 replicate wells in each well;

[0067] Table 2 Oil secretion inhibition experiment scheme

[0068]

[0069] After incubation for 48 h, the supernatant was discarded, and the cells were washed twice with PBS, and then 100 μL of 10 μg / mL Nile Red dye (Shanghai Yuanye Biological, S02N11G129713) was added to the fluorescence quantitative experiment group, and 15 μg / mL fluorescein diacetate FDA (Shanghai Yuanye Biological, J22A11H122040) was added to the fluorescence quantitative control group, and incubated for 5 min, and the released fluorescence was detected on a multifunctional enzyme label instrument. The excitation wavelengths of 485 nm and 494 nm and the absorption wavelengths of 565 nm and 523 nm were used for the detection of the fluorescence intensity of Nile Red and FDA, respectively;

[0070] The results were determined by the ratio of Nile Red and FDA (OD ratio), and the percentage of intracellular neutral lipids (%) = experimental group OD ratio / control group OD ratio x 100%. The relative neutral lipid content (%) = neutral lipid percentage / model control group neutral lipid percentage x 100%. The specific data are shown in Table 3.

[0071] Table 3 Oil secretion improvement rate data of samples in each group

[0072] Group / property Relative neutral lipid content (%) Example 1 61.7 Example 2 70.4 Example 3 65.1 Example 4 74.7 Example 5 72.1 Comparative Example 1 80.4 Comparative Example 2 83.0 Comparative Example 3 87.6 Comparative Example 4 92.2 Comparative Example 5 95.4 Negative control group (NT) 59.6 Model control group (M) 100 Positive control group (PC) 82.6

[0073] The intracellular neutral lipid content directly corresponds to the amount of oil synthesis, and the higher the content, the more oil the cell produces. If the percentage of neutral lipids in the sample group is lower than that in the model group, it means that the sample inhibits oil synthesis, and the lower the percentage, the stronger the oil control effect; otherwise, the oil control effect is weak or has no oil control effect.

[0074] As can be seen from Table 3, in combination with the data of Examples 1-5, when the weight ratio of the B. rosea seed extract, the Pseudoalteromonas fermentate extract, the O. fortunei bark extract, the C. ambrosioides leaf extract and the M. gordonii extract is (0.1-0.5):(0.8-1.5):(0.3-0.8):(3-5):(1-5), the oil control effect of the composition is at a relatively optimal level.

[0075] As can be seen from the data of Examples 1 and Comparative Examples 1-5, the absence of any one ingredient in the composition will reduce the oil control performance of the composition, which may be because the B. rosea seed extract, the Pseudoalteromonas fermentate extract, the O. fortunei bark extract, the C. ambrosioides leaf extract and the M. gordonii extract have a synergistic inhibitory effect on the secretion of skin oil. In particular, the B. rosea seed extract and the Pseudoalteromonas fermentate extract have a significant synergistic effect, which can reduce the secretion of sebum from the aspects of inhibiting the proliferation of sebaceous gland cells and slowing down the maturation of sebaceous gland cells.

[0076] Test Example 2: P. acnes inhibition rate test of each group of compositions

[0077] Experimental method: Configure liquid sulfite medium (FT medium, RingKai Microorganism, REF: 028033), inoculate 0.2wt% P. acnes (Guangdong Microorganism Institute) into the medium, cultivate at 37°C for 48h to form a bacterial solution. Mix the sample to be tested (the oil control and acne-removing compositions of Examples 1-5 and Comparative Examples 1-5) with DMSO to prepare a sample solution with a volume percentage of 0.01% for standby, then add 180μL of the bacterial solution to a 96-well plate, and then add 40μL of each sample solution to prepare a sample group, and set up a control group (bacterial solution without sample solution) respectively. After 24h of cultivation, the OD value of each well was measured by an enzyme marker instrument. The smaller the OD value, the clearer the liquid, the worse the activity of the bacteria, and the better the bacteriostatic effect. The bacteriostatic rate was calculated according to the following formula: Bacteriostatic rate (%) = (control group OD value - sample group OD value) / control group OD value x 100%; see Table 4 for specific data.

[0078] Table 4: P. acnes inhibition rate data of each group of samples

[0079] Group / property P. acnes inhibition rate (%) Example 1 91.5 Example 2 89.4 Example 3 92.1 Example 4 85.3 Example 5 83.9 Comparative Example 1 70.5 Comparative Example 2 72.7 Comparative Example 3 62.5 Comparative Example 4 58.4 Comparative Example 5 74.8

[0080] As can be seen from Table 4, in combination with the data of Examples 1-5, when the weight ratio of the B. excelsa seed extract, the Pseudoalteromonas fermentate extract, the P. fortunei bark extract, the C. sibiricum leaf extract, and the M. gordonii extract is (0.1-0.5):(0.8-1.5):(0.3-0.8):(3-5):(1-5), the composition has a better inhibitory effect on P. acnes.

[0081] As can be seen from the data of Examples 1 and Comparative Examples 1-5, the absence of any one component in the composition reduces the oil control performance of the composition, which may be because the B. excelsa seed extract, the Pseudoalteromonas fermentate extract, the P. fortunei bark extract, the C. sibiricum leaf extract, and the M. gordonii extract have a synergistic effect on inhibiting P. acnes, and in particular, the P. fortunei bark extract can specifically kill P. acnes, thereby eliminating the cause of acne from the root, and the C. sibiricum leaf extract can rapidly inhibit the inflammatory response caused by bacteria by inhibiting the NF-kB pathway, and the two components can synergistically prevent and resolve red and swollen acne, and avoid pigmentation and scarring.

[0082] Application Examples 1-5 and Comparative Application Examples 1-5

[0083] The compositions of Examples 1-5 and Comparative Examples 1-5 were added to an oil control acne-removing lotion at a concentration of 5 wt%, to obtain the lotion of Application Examples 1-5 and Comparative Application Examples 1-5, and the formula is shown in Table 5.

[0084] The preparation method of the oil control acne-removing lotion of Application Examples 1-5 and Comparative Application Examples 1-5 comprises the following steps:

[0085] S1, mix the humectant, thickening agent, chelating agent, and deionized water, and homogenize at 80°C and 1200 rpm for 5 min to obtain an aqueous phase;

[0086] S2, mix the emulsifier components, and homogenize at 80°C and 1200 rpm for 5 min to obtain an oil phase;

[0087] S3, uniformly stir the aqueous phase and the oil phase at 80°C, and after the temperature is reduced to 60°C, add the preservative, and uniformly stir at a stirring speed of 300 rpm, and after the temperature of the mixture is reduced to 40°C, add the components of the oil control acne-removing composition specially developed for men, continue to stir for 5 min, and finally add the pH adjuster to adjust the pH, to obtain the oil control acne-removing lotion.

[0088] Table 5 Formula of the oil control acne-removing lotion of Application Examples 1-5 and Comparative Application Examples 1-5

[0089]

[0090]

[0091] Comparative Application Example 6

[0092] The emulsion of Comparative Application Example 6 was prepared without the addition of the oil-control and acne-removing composition, and an equal amount of deionized water was used instead of the oil-control and acne-removing composition, and the preparation method was the same as that of Application Example 1.

[0093] Test Example 3: Human acne-removing and repair effect test of each group of emulsions

[0094] Screening criteria:

[0095] Volunteers with mild acne (e.g., the number of papules and pustules was ≤10) and independent acne marks with a diameter of ≥3 mm on the face were recruited.

[0096] The value of transepidermal water loss (TEWL) was ≥20 g / m2·h (measured using Tewameter™ Hex).

[0097] Exclusion criteria: those who had used hormone drugs, anti-acne drugs, or had undergone facial medical aesthetic treatment in the recent 1 month; those who were allergic to the ingredients of the test samples; pregnant or lactating women.

[0098] Grouping and number of people:

[0099] The eligible volunteers were randomly divided into 11 groups (Application Examples 1-5 and Comparative Application Examples 1-6), with 5 people in each group.

[0100] (3) Sample application method

[0101] Test samples: emulsions prepared in Application Examples 1-5 and Comparative Application Examples 1-6 (double-blind numbered), among which the emulsion prepared in Comparative Application Example 6 was the blank control group, and the rest of the application examples and comparative examples were sample groups.

[0102] Usage: The volunteers applied 1 mL of the sample evenly to the whole face after cleansing in the morning and evening every day, and gently massaged until complete absorption.

[0103] (4) Test period and procedure

[0104] Test period: lasted for 14 days (D0, D 14 ).

[0105] Visit time points: instrument detection was performed at D0 (baseline period), D 14 (end of test).

[0106] Preparation before detection:

[0107] a) The subjects used a unified non-irritating cleansing product to clean the face after visiting;

[0108] b) Rested in a constant temperature and humidity environment (temperature 21±1℃, humidity 50±10%) for 30 minutes;

[0109] c) Keep the eyes closed and relaxed during the test, avoid facial expression.

[0110] (5) Test index

[0111] Anti-acne efficacy:

[0112] The facial acne quality changes were quantified and photographed by using the facial image analyzer VISIA-CR, and the number of acne was counted.

[0113] Repairing and redness fading efficacy:

[0114] The skin barrier repairing effect and redness fading effect were evaluated by measuring the TEWL value and facial erythema using the skin moisture loss tester (TewameterTM Hex) and MX 18, respectively.

[0115] The facial skin condition on the 14th day after using the test product was observed, so as to comprehensively evaluate the anti-acne, redness fading and repairing effects of the test product.

[0116] The calculation formula of each evaluation parameter is as follows:

[0117] The improvement rate (%) of each index = (the average value before use - the average value after use) / the average value before use x 100%; the data are shown in Table 6.

[0118] Table 6: Test data results of each emulsion on human body

[0119] Group / property Improvement rate in number of comedones (%) Improvement rate in TEWL (%) Improvement rate in erythema (%) Application Example 1 45.0 31.8 40.1 Application Example 2 39.5 31.1 33.4 Application Example 3 41.9 30.2 37.4 Application Example 4 34.9 28.5 28.5 Application Example 5 36.4 26.0 30.2 Comparative Application Example 1 16.3 13.2 15.5 Comparative Application Example 2 19.1 14.3 18.3 Comparative Application Example 3 22.7 12.7 13.2 Comparative Application Example 4 25.6 10.6 11.2 Comparative Application Example 5 29.3 9.7 9.8 Comparative Application Example 6 7.5 6.8 7.3

[0120] As shown in Table 6, the anti-acne and repairing effects of each emulsion are improved compared with the emulsion of comparative application example 6 (blank control group without adding the composition).

[0121] According to the data of application examples 1-5, when the weight ratio of the B. balsamifera seed extract, the Pseudoalteromonas ferment extract, the P. fortunei bark extract, the C. australis leaf extract and the M. gordonii extract is (0.1-0.5) :(0.8-1.5) :(0.3-0.8) :(3-5) :(1-5), the anti-acne and repairing effects of the emulsion are better.

[0122] According to the data of application example 1 and comparative application examples 1-5, if one component is missing in the composition in the emulsion, the oil control performance of the composition will be reduced, which may be because the B. balsamifera seed extract, the Pseudoalteromonas ferment extract, the P. fortunei bark extract, the C. australis leaf extract and the M. gordonii extract are synergistic, so as to relieve the acne problem of men from multiple aspects such as oil control, antibacterial, anti-inflammatory, repairing, moisturizing and the like.

[0123] Finally, it should be noted that the above examples are merely intended to illustrate the technical solutions of the present application and not to limit the protection scope of the present application. Although the present application has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or equivalently replaced without departing from the essence and scope of the technical solutions of the present application.

Claims

1. A men's-specific oil-controlling and acne-removing composition, characterized in that, It includes the following components: rosewood seed extract, *Pseudomonas aeruginosa* fermentation product extract, *Phellodendron amurense* bark extract, *Artichoke leaf* extract, and *Magnolia sieboldii* extract, wherein the weight ratio of the rosewood seed extract, *Pseudomonas aeruginosa* fermentation product extract, *Phellodendron amurense* bark extract, *Artichoke leaf* extract, and *Magnolia sieboldii* extract is (0.05-2):(0.5-2):(0.2-1):(0.2-5):(0.1-5).

2. The oil-controlling and acne-removing composition for men, as described in claim 1, is characterized in that... The weight ratio of the rosewood seed extract, the Pseudomonas aeruginosa fermentation product extract, the Phellodendron amurense bark extract, the artichoke leaf extract, and the Magnolia sieboldii extract is (0.1-0.5):(0.8-1.5):(0.3-0.8):(3-5):(1-5).

3. The oil-controlling and acne-removing composition for men, as described in claim 1, is characterized in that... The weight ratio of the rosewood seed extract, *Pseudomonas aeruginosa* fermentation product extract, *Phellodendron amurense* bark extract, *Artichoke leaf* extract, and *Magnolia denudata* extract is 0.2:1:0.5:2:

2.

4. The oil-controlling and acne-removing composition for men, as described in claim 1, is characterized in that... The source of the component is selected from at least one of (I)-(II): (I) The rosewood seed extract was purchased from Xi'an Tiankang Biotechnology Co., Ltd.; (II) The Pseudomonas alterniflora fermentation product extract was purchased from Lipotec. (III) The Phellodendron bark extract was purchased from Guangzhou Heji Biotechnology Co., Ltd.; (IV) The artichoke leaf extract was purchased from Zhenghe (Guangzhou) Biotechnology Co., Ltd.; (V) Magnolia officinalis extract was purchased from Guangzhou Jinbaolai Biotechnology Co., Ltd.

5. The use of the men's oil-controlling and acne-removing composition according to any one of claims 1-4 in the preparation of cosmetics.

6. The application of the men's-specific oil-controlling and acne-removing composition as described in claim 5 in the preparation of cosmetics, characterized in that, The cosmetic is one of toner, lotion, cream, mask, and serum, and the amount of the oil-controlling and acne-removing composition added is 2%-8% of the total weight of the cosmetic.

7. An oil-controlling and acne-removing lotion, characterized in that, The ingredients comprise the following ingredients by weight percentage: 2%-8% of the men's oil-controlling and acne-removing composition according to any one of claims 1-4, 4%-8% of moisturizer, 0.1%-0.3% of thickener, 0.03%-0.1% of chelating agent, 5%-8% of emulsifier, 0.5%-2% of preservative, 0.01%-0.3% of pH adjuster, and the balance being deionized water.

8. The oil-controlling and acne-removing lotion as described in claim 7, characterized in that, The raw material is selected from at least one of (a)-(f): (a) The moisturizer is at least one of allantoin, betaine, β-glucan, trehalose, caprylyl glycol, dipropylene glycol, D-panthenol, sodium hyaluronate, 1,2-butanediol, glycerin, budding stalk polysaccharide and ceramide; (b) The thickener is at least one of xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, ammonium acryloyl dimethyl taurate / VP copolymer and sclerotium gum; (c) The chelating agent is EDTA-2Na; (d) The emulsifier is at least one of the following: coconut oil alcohol-octanoate / decanoate, polydimethylsiloxane, hydrogenated palm kernel oil, cetearyl alcohol, polyglycerol-6 distearate, and polymethylsilsesquioxane; (e) The preservative is at least one of 1,3-propanediol, 1,2-hexanediol and p-hydroxyacetophenone; (f) The pH adjuster is at least one of arginine, tromethamine and disodium EDTA.

9. The preparation method of the oil-controlling and acne-removing lotion according to claim 8, characterized in that, Includes the following steps: S1. Mix the humectant, thickener, chelating agent and deionized water, and homogenize at 75-85℃ to obtain the aqueous phase; S2. Homogenize the emulsifier at 75-85℃ to obtain the oil phase; S3. Stir the aqueous phase and oil phase evenly, and add the preservative after cooling to 55-65℃. Stir evenly, and add the components of the men's specially formulated oil-controlling and acne-removing composition after cooling to 35-45℃. Stir evenly, and finally add the pH adjuster to adjust the pH to obtain the oil-controlling and acne-removing lotion.

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