Hair growth composition
By combining plant extracts such as Quinoa seeds, this product addresses the issues of limited efficacy in existing hair growth products and the side effects of traditional drugs, achieving significant hair loss prevention and hair regrowth effects and promoting hair growth.
Patent Information
- Application Number
- CN202511574439.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-31
- Publication Date
- 2025-12-16
AI Technical Summary
Existing hair growth products have limited efficacy, insufficient plant-based ingredients, and traditional drug treatments have side effects, making them ineffective in preventing hair loss and promoting hair growth.
This product uses a combination of Quinoa seed extract, bamboo shoot extract, kudzu root extract, arborvitae leaf extract, ginseng extract, astragalus extract, fleeceflower root extract, pine needle extract, ginger root extract, privet fruit extract, ginkgo leaf extract, fig leaf extract, rosemary leaf extract, houttuynia cordata extract, and ethanol. This combination works synergistically to nourish the scalp, inhibit sebum secretion, reduce inflammation and soothe, maintain the microecological environment, and promote hair growth.
It has significant effects in preventing hair loss and promoting hair growth, reduces scalp inflammation, promotes blood supply to hair follicles, prolongs the growth phase of hair follicles, improves microcirculation, increases hair growth efficiency, and reduces adverse reactions.
Smart Images
Figure CN121129729A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of cosmetics, and more specifically, to a hair growth composition and its preparation method. Background Technology
[0002] Hair loss is an abnormal shedding of hair caused by various factors, and is divided into physiological hair loss and non-physiological hair loss (pathological hair loss). Hair growth typically includes three phases: the anagen (growth) phase (active growth, approximately 90% of hair), the catagen (reduction, less than 10% of hair), and the telogen (resting) phase (5% to 10% of hair). Normally, hair will shed physiologically during the catagen and telogen phases; losing 50-100 hairs per day is considered normal, and a dynamic balance is maintained between hair growth and hair loss. However, if more than 100 hairs are lost per day, with fewer hairs entering the anagen phase than falling out during the telogen phase, the hair will become sparse. This excessive hair loss is considered non-physiological hair loss, or pathological hair loss. Pathological hair loss not only affects a patient's appearance but also causes significant psychological stress and burden.
[0003] Pathological hair loss mainly includes androgenetic alopecia, alopecia areata, scarring alopecia, and telogen effluvium, etc., and its causes are diverse, mainly involving factors such as genetics, endocrine disorders, immune abnormalities, and mental stress. At present, the mechanisms of hair loss prevention mainly cover the following aspects: (1) anti-androgen effect; (2) regulation of hair follicle growth cycle; (3) reduction of hair follicle damage; (4) improvement of microcirculation and energy metabolism; (5) opening of potassium ion channels. The main drugs for treating hair loss in medicine are minoxidil and finasteride, which are used for androgenetic alopecia. Minoxidil was initially used as a vasodilator, but it was later proven to promote hair growth or slow down the hair loss process, and therefore it was used for hair loss treatment. Its mechanism of action mainly includes: dilating blood vessels, increasing blood and oxygen supply to hair follicles; promoting the division of epithelial keratinocytes, stimulating hair growth, etc. Minoxidil is currently available in two main concentrations: 2% and 5%. The 5% concentration is more effective, but higher concentrations increase scalp irritation and may cause adverse reactions such as contact dermatitis and facial hirsutism. Finasteride, as a 5α-reductase inhibitor, can inhibit the conversion of peripheral testosterone to dihydrotestosterone (DHT), reducing DHT concentrations in the blood and prostate, thereby reducing the inhibitory effect of DHT on hair follicles and promoting hair growth. However, oral finasteride treatment for hair loss has certain side effects, including allergic reactions and liver dysfunction in some individuals.
[0004] In recent years, there has been an increasing number of research reports on the development of plant extracts for preventing hair loss. Plant-derived ingredients have attracted attention due to their relative safety, effectiveness, and ease of use. However, hair growth products on the market still generally have limitations such as single efficacy and insufficient active ingredients. Summary of the Invention
[0005] To address the shortcomings of existing technologies, the present invention provides a hair growth composition comprising or composed of the following components: Quinoa seed extract, bamboo shoot extract, kudzu root extract, arborvitae leaf extract, ginseng extract, astragalus extract, fleeceflower root extract, pine needle extract, ginger root extract, privet fruit extract, ginkgo leaf extract, fig leaf extract, rosemary leaf extract, houttuynia cordata extract, and ethanol.
[0006] The hair growth composition of this invention has a synergistic effect among its components, which can nourish the scalp, inhibit sebum secretion, reduce inflammation and soothe the skin, and maintain the scalp's microecological environment, thus having significant effects in preventing hair loss and promoting hair growth. Attached Figure Description
[0007] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.
[0008] Figure 1 This is a schematic diagram illustrating the effect of the hair growth composition in Example 2 on improving hair loss on the crown; Figure 2 This is a schematic diagram illustrating the effect of the hair growth composition in Example 2 on improving a sparse hairline; Figure 3 This is a schematic diagram illustrating the effect of the hair growth composition in Example 2 on improving thinning hair on the crown and regulating scalp oil. Figure 4 This is a comparative diagram showing the effect of the composition in Comparative Example 1 on hair loss on the top of the head; Figure 5 This is a schematic diagram showing the effect of the composition in Comparative Example 1 on hair loss in people with fine and sparse hair. Detailed Implementation
[0009] According to the hair growth composition of the present invention, the composition comprises or is composed of the following components: Quinoa seed extract, bamboo shoot extract, kudzu root extract, arborvitae leaf extract, ginseng extract, astragalus extract, fleeceflower root extract, pine needle extract, ginger root extract, privet fruit extract, ginkgo leaf extract, fig leaf extract, rosemary leaf extract, houttuynia cordata extract, ethanol.
[0010] In one embodiment, the weight parts of each component are as follows: The ingredients include: 25-45 parts of Quinoa seed extract, 5-25 parts of Bamboo shoot extract, 0.1-1.5 parts of Pueraria lobata root extract, 1-5 parts of Platycladus orientalis leaf extract, 0.5-5.5 parts of Ginseng extract, 0.1-1 part of Astragalus membranaceus extract, 2-4 parts of Polygonum multiflorum extract, 1-5 parts of Pine needle extract, 0.5-5 parts of Ginger root extract, 0.5-3 parts of Ligustrum lucidum extract, 1-5 parts of Ginkgo biloba leaf extract, 0.1-2 parts of Fig leaf extract, 1-5 parts of Rosemary leaf extract, 1-10 parts of Houttuynia cordata extract, and 10-50 parts of ethanol.
[0011] In one embodiment, the weight parts of each component are as follows: 38-42 parts of Quinoa seed extract, 15-24 parts of Bamboo shoot extract, 0.6-1.2 parts of Pueraria lobata root extract, 3.5-4.5 parts of Platycladus orientalis leaf extract, 4.2-5.2 parts of ginseng extract, 0.3-0.8 parts of Astragalus membranaceus extract, 1-3 parts of Polygonum multiflorum extract, 3.5-4.5 parts of pine needle extract, 1-3 parts of ginger root extract, 1.5-2.5 parts of Ligustrum lucidum extract, 2-3 parts of Ginkgo biloba leaf extract, 0.5-1.5 parts of Fig leaf extract, 2-4 parts of Rosemary leaf extract, 3-8 parts of Houttuynia cordata extract, and 15-25 parts of ethanol.
[0012] In one embodiment, the weight parts of each component are as follows: 40 parts of Quinoa seed extract, 20 parts of Bamboo shoot extract, 1 part of Pueraria lobata root extract, 4 parts of Platycladus orientalis leaf extract, 5 parts of ginseng extract, 0.5 parts of Astragalus membranaceus extract, 2 parts of Polygonum multiflorum extract, 4 parts of pine needle extract, 2 parts of ginger root extract, 2 parts of Ligustrum lucidum extract, 3 parts of Ginkgo biloba leaf extract, 1 part of Fig leaf extract, 3 parts of Rosemary leaf extract, 5 parts of Houttuynia cordata extract, and 20 parts of ethanol.
[0013] According to the composition of the present invention, in one embodiment, the quinoa seed extract is prepared by the following method: Weigh 25-35 g of dried Quinoa seed bran powder and place it in a beaker. Add 500-700 mL of deionized water, 0.50-0.70 g of 1.5-2.5% cellulase and pectinase, with a mass ratio of cellulase to pectinase of 0.5-1.5:1. Place the beaker in a water bath for enzymatic extraction. The enzymatic extraction time is 1.5-2.5 h, the enzymatic extraction temperature is 45-51℃, the pH value is 4.5-5.1, and the material-to-liquid ratio is 1:18-22. After enzymatic extraction, inactivate the extract at 80-90℃ for 3-7 min. After inactivation, sonicate at room temperature in an ultrasonic cleaner for 1.5-2.5 h. Then, filter the extract using a vacuum filtration device.
[0014] Weigh 25-35 g of dried bamboo shoot powder and place it in a beaker. Add 375-525 mL of deionized water, 0.50-0.70 g of cellulase and papain at a concentration of 1.5-2.5% (mass ratio of cellulase to papain: 0.5-1.5:1), and place the beaker in a water bath for enzymatic extraction. The enzymatic extraction time is 2.5-3.5 h, the enzymatic extraction temperature is 40-50 ℃, the pH value is 5.2-6.0, and the material-to-liquid ratio is 1:12-18. After enzymatic extraction, inactivate the extract at 82-88 ℃ for 3-7 min, and then filter the extract using a vacuum filtration device.
[0015] According to the composition of the present invention, in one embodiment, the Platycladus orientalis leaf extract is prepared by the following method: Weigh 25-35 g of dried arborvitae leaf powder and place it in a beaker. Add 375-525 mL of 45-55% ethanol solution to the beaker. Place the beaker in an ultrasonic cleaner for ultrasonic-assisted extraction. The extraction time is 40-50 min, the material-to-liquid ratio is 1:12-18, and the extraction temperature is 45-55℃. After extraction, filter the extract using a vacuum filter and concentrate the extract by vacuum evaporation using a rotary evaporator to concentrate the material-to-liquid ratio to 1:7-8.
[0016] According to the composition of the present invention, the pine needle extract is prepared by the following method: 25-35 g of dried pine needle powder is weighed and placed in a beaker, 375-525 mL of deionized water is added to the beaker, and the beaker is placed in an ultrasonic cleaner for ultrasonic-assisted extraction. The extraction temperature is 45-55℃, the material-to-liquid ratio is 1:12-18, and the extraction time is 1.5-2.5 h. After the extraction is completed, the extract is filtered using a vacuum filtration device.
[0017] According to the composition of the present invention, the preparation method of the fig leaf extract is as follows: Weigh 15-25 g of dried fig leaf powder into a beaker, add 300-500 mL of 25-35% ethanol solution to the beaker, place the beaker in an ultrasonic cleaner for ultrasonic extraction, the extraction temperature is 45-55℃, the material-liquid ratio is 1:15-25, and the extraction time is 35-45 min. After ultrasonic extraction, filter the extract using a vacuum filtration device, and concentrate the extract by vacuum evaporation using a rotary evaporator to concentrate the material-liquid ratio to 1:12-16.
[0018] According to the composition of the present invention, the rosemary leaf extract is prepared by the following method: 25-35 g of dried rosemary leaves are weighed and placed in a beaker, 500-700 mL of 65-75% ethanol solution is added to the beaker, the beaker is placed in an ultrasonic cleaner for ultrasonic-assisted extraction, the ultrasonic time is 40-50 min, the material-to-liquid ratio is 1:15-25, after extraction, the extract is filtered using a vacuum filtration device, and the extract is concentrated by vacuum evaporation using a rotary evaporator, the material-to-liquid ratio is concentrated to 1:4-8 to obtain the extract.
[0019] The functions of each component in the hair growth composition of the present invention are as follows: (1) Pueraria lobata extract: Pueraria lobata extract has a certain inhibitory effect on 5α-reductase and can treat androgenetic alopecia; (2) Quinoa seed extract: combats scalp inflammation and provides nutrients for hair growth. Quinoa, also known as quinoa, is rich in saponins, proteins, polysaccharides and other components in its seed extract. Quinoa saponins have anti-inflammatory and permeation-promoting effects, while quinoa protein contains eight essential amino acids, including lysine, methionine + cysteine, threonine, and tryptophan. Among these, lysine, methionine, and cysteine are amino acids required for hair growth. (3) Bamboo shoot extract: Bamboo shoots are rich in amino acids, which provide nutrients for hair growth; (4) Platycladus orientalis leaf extract: It inhibits 5-α reductase, promotes hair follicle regeneration and promotes the reconstruction of blood vessels around hair follicles by upregulating growth factors such as Wnt10b, β-catenin protein, IGF-1, and VEGF, and has antibacterial, anti-inflammatory and antioxidant effects; Platycladus orientalis leaf extract is rich in flavonoids. (5) Ginseng extract: inhibits 5-α reductase; (6) Astragalus extract: Baicalin and plant extracts can activate the Wnt signaling pathway; (7) Polygonum multiflorum extract: inhibits 5α-reductase and regulates the hair follicle growth cycle by upregulating different signaling pathways such as FGF-7, HGF, β-catenin and Shh protein; (8) Pine needle extract: It can improve microcirculation, strengthen hair follicle nutrition, enhance hair follicle cells, and reduce hair loss; (9) Ginger root extract: improves microcirculation around hair follicles, provides more nutrients to hair follicles, and promotes hair growth; (10) Ligustrum lucidum extract: inhibits 5-α reductase activity and promotes hair growth; (11) Ginkgo biloba extract: inhibits FGF5 activity, prolongs the hair follicle growth phase, and promotes hair growth; (12) Fig leaf extract: Figs are rich in phenols and flavonoids, which have antioxidant activity; Fig leaf extract can inhibit 5-α reductase and reduce hair follicle inflammatory response by downregulating TNF-α and IL-1, thus reducing hair follicle damage. (13) Rosemary leaf extract: inhibits 5α-reductase. Rosemary leaves are rich in phenolic acids, terpenes and flavonoids, which have antioxidant and antibacterial effects. (14) Houttuynia cordata extract: Houttuynia cordata is rich in active ingredients such as flavonoids and polysaccharides, which have anti-inflammatory and antioxidant stress effects. Houttuynia cordata extract can promote the proliferation of dermal papillary cells and prolong the hair follicle growth period. (15) Ethanol: It has a good permeation-enhancing effect and helps other components to be absorbed through the skin.
[0020] The sources of the various extracts in the following examples and comparative examples are as follows: 1. Pueraria lobata extract was purchased from Shanghai Xinzhide Industrial Development Co., Ltd., product name: TECHNOBLE Concentrated Pueraria Isoflavones; 2. Preparation of Quinoa Seed Extract: Quinoa seed aqueous extract Weigh 30 g of dried Quinoa seed bran powder and add 600 mL of deionized water, 2% cellulase and pectinase (1:1) to a beaker. Place the beaker in a water bath for enzymatic extraction. The enzymatic extraction time is 2 h, the enzymatic extraction temperature is 48 ℃, the pH value is 4.8, and the material-liquid ratio is 1:20. After the enzymatic extraction is completed, the extract is inactivated at 85 ℃ for 5 min. After inactivation, it is ultrasonically cleaned at room temperature for 2 h. Then, the extract is filtered using a vacuum filtration device. 3. The extract of *Lycoris radiata* shoots is an aqueous extract of *Lycoris radiata* shoots. The preparation method is as follows: Weigh 30 g of dried *Lycoris radiata* shoot powder and add 450 mL of deionized water, 2% cellulase and papain (1:1) to a beaker. Place the beaker in a water bath for enzymatic extraction. The enzymatic extraction time is 3 h, the enzymatic extraction temperature is 45 ℃, the pH value is 5.7, and the material-to-liquid ratio is 1:15. After the enzymatic extraction is completed, the extract is inactivated at 85 ℃ for 5 min. Then, the extract is filtered using a vacuum filtration device. 4. The extract of Platycladus orientalis leaves is an ethanol extract of Platycladus orientalis leaves. The preparation method is as follows: Weigh 30 g of dried Platycladus orientalis leaf powder and add 450 mL of 50% ethanol solution to a beaker. Place the beaker in an ultrasonic cleaner for ultrasonic-assisted extraction. The extraction time is 45 min, the material-liquid ratio is 1:15, and the extraction temperature is 50 ℃. After the extraction, filter the extract using a vacuum filtration device and concentrate the extract by vacuum evaporation using a rotary evaporator. The material-liquid ratio is concentrated to 1:7.5 to obtain the final product. 5. The ginseng extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.; model number YH-52277; 6. The Astragalus extract was purchased from Guangzhou Sinoco Biotechnology Co., Ltd., and the product name is SYMORKO Astragalus Extract. 7. Polygonum multiflorum extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd.; model number HSWTQW; 8. Pine needle extract is a water extract of pine needles. Its preparation method is as follows: Weigh 30 g of dried pine needle powder and add deionized water to a beaker. Place the beaker in an ultrasonic cleaner for ultrasonic-assisted extraction. The extraction temperature is 50℃, the material-to-liquid ratio is 1:15, and the extraction time is 2 h. After the extraction is completed, the extract is filtered by a vacuum filtration device. 9. Ginger root extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.; model number YH-51061; 10. The privet fruit extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.; model number YH-52574. 11. Ginkgo biloba extract was purchased from Shaanxi Yiruinong Biotechnology Co., Ltd.; product name: YRN. 12. Fig leaf extract is an alcoholic extract of fig leaves. Its preparation method is as follows: Weigh 20 g of dried fig leaf powder and add 400 mL of 30% ethanol solution to a beaker. Place the beaker in an ultrasonic cleaner for ultrasonic extraction. The extraction temperature is 50℃, the material-to-liquid ratio is 1:20, and the extraction time is 40 min. After ultrasonic extraction, filter the extract using a vacuum filtration device and concentrate the extract by vacuum evaporation using a rotary evaporator. The material-to-liquid ratio is concentrated to 1:14 to obtain the product. 13. Rosemary leaf extract is an alcoholic extract of rosemary leaves. Its preparation method is as follows: Weigh 30 g of dried rosemary leaves and add 600 mL of 70% ethanol solution to a beaker. Place the beaker in an ultrasonic cleaner for ultrasonic-assisted extraction. The ultrasonic time is 45 min and the material-liquid ratio is 1:20. After extraction, filter the extract using a vacuum filtration device and concentrate the extract by vacuum evaporation using a rotary evaporator. The material-liquid ratio is concentrated to 1:6 to obtain the extract. 14. The Houttuynia cordata extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.; model number YH-51062. 15. Ethanol was purchased from Shanghai Titan Technology Co., Ltd., and was of analytical grade.
[0021] Other raw materials: cellulase (SPE-017L, purchased from Xiasheng Enzyme Biotechnology Co., Ltd.); pectinase (SPE-006, purchased from Xiasheng Enzyme Biotechnology Co., Ltd.); papain (purchased from Xiasheng Enzyme Biotechnology Co., Ltd.). Example 1
[0022] A hair growth composition comprising the following raw materials in parts by weight: 30 parts of Quinoa seed extract, 5 parts of Bamboo shoot extract, 0.1 parts of Pueraria lobata root extract, 2 parts of Platycladus orientalis leaf extract, 1 part of Ginseng extract, 0.1 parts of Astragalus membranaceus extract, 1 part of Polygonum multiflorum extract, 1 part of Pine needle extract, 0.5 parts of Ginger root extract, 0.5 parts of Ligustrum lucidum extract, 1 part of Ginkgo biloba leaf extract, 0.1 parts of Fig leaf extract, 1 part of Rosemary leaf extract, 5 parts of Houttuynia cordata extract, and 50 parts of ethanol.
[0023] Preparation method of hair growth composition: Take each of the above raw materials separately, mix and stir them evenly to obtain the hair growth composition. Example 2
[0024] A hair growth composition comprising the following raw materials in parts by weight: 40 parts of Quinoa seed extract, 20 parts of Bamboo shoot extract, 1 part of Pueraria lobata root extract, 4 parts of Platycladus orientalis leaf extract, 5 parts of ginseng extract, 0.5 parts of Astragalus membranaceus extract, 2 parts of Polygonum multiflorum extract, 4 parts of pine needle extract, 2 parts of ginger root extract, 2 parts of Ligustrum lucidum extract, 3 parts of Ginkgo biloba leaf extract, 1 part of Fig leaf extract, 3 parts of Rosemary leaf extract, 5 parts of Houttuynia cordata extract, and 20 parts of ethanol.
[0025] Preparation method of hair growth composition: Take each of the above raw materials separately, mix and stir them evenly to obtain the hair growth composition. Example 3
[0026] A hair growth composition comprising the following raw materials in parts by weight: 30 parts of Quinoa seed extract, 20 parts of Bamboo shoot extract, 0.5 parts of Pueraria lobata root extract, 4 parts of Platycladus orientalis leaf extract, 5 parts of ginseng extract, 1 part of Astragalus membranaceus extract, 4 parts of Polygonum multiflorum extract, 4 parts of pine needle extract, 5 parts of ginger root extract, 2 parts of Ligustrum lucidum extract, 3 parts of Ginkgo biloba leaf extract, 1 part of Fig leaf extract, 3 parts of Rosemary leaf extract, 5 parts of Houttuynia cordata extract, and 30 parts of ethanol.
[0027] Preparation method of hair growth composition: Take each of the above raw materials separately, mix and stir them evenly to obtain the hair growth composition.
[0028] Comparative Example 1 A hair growth composition comprising the following raw materials in parts by weight: 20 parts of Quinoa seed extract, 10 parts of Bamboo shoot extract, 1 part of Pueraria lobata root extract, 2 parts of pine needle extract, 2 parts of Ligustrum lucidum extract, 1 part of Fig leaf extract, 3 parts of Rosemary leaf extract, and 20 parts of ethanol.
[0029] Preparation method of hair growth composition: Take each of the above raw materials separately, mix and stir them evenly to obtain the hair growth composition.
[0030] Experiment Example 4 1. Experimenters: Thirty volunteers aged 18-60 who met the experimental requirements were selected as experimental subjects, and skin patch tests were conducted using standardized patch test materials.
[0031] Table 1 Skin Grading Standards for Closed Patch Test
[0032] 2. Experimental method: Select an area not exceeding 50 mm². 2 A plaster applicator with a depth of approximately 1 mm is used. The test sample is placed in the plaster applicator chamber, with an amount of approximately 0.020–0.025 g (solid or semi-solid). The test samples are the compositions prepared in Examples 1–3, and the control well is a blank control (without any substance). The plaster applicator containing the test sample is applied to the back or flexor side of the forearm of the subject, and gently pressed with the palm of the hand to ensure even application to the skin, for 24 hours. Skin reactions are observed according to the table standards at 30 minutes (after the indentation disappears) and 24 hours after removing the plaster applicator, and the results are recorded.
[0033] 3. Experimental Results: Table 2 Patch Test Results
[0034] The patch test results of the compositions prepared in Examples 1-3 are shown in Table 2. A small number of suspicious reactions were observed in Examples 1 and 3, while all results in Example 2 were negative. Further testing was conducted using Example 2.
[0035] Experimental Example 5: 1. Participants: Thirty participants with hair loss were selected for the trial. The BASP (Basic and Specific Classification) method was used to classify the participants' hair loss conditions. The basic information of the participants is shown in Table 3.
[0036] Table 3 Basic Information of Subjects
[0037] 2. Experimental Method: Each person used the hair growth composition prepared in Example 2 once every two days, about 1mL-5mL each time, applied to the hair loss area. The dosage was adjusted appropriately according to the degree of hair loss. Before using the composition, the scalp and hair were washed and dried. The composition was then placed in a massage comb and applied to the sparse hair areas while massaging, allowing the scalp to fully absorb it.
[0038] 3. Experimental results: See Table 4 for the data. As can be seen from the data in Table 4, the hair growth composition has a very good effect on hair growth and prevention of hair loss.
[0039] Table 4 Hair regrowth effect of Example 2
[0040] Examples 1, 2, and 3 demonstrate the significant hair growth effect of the hair growth composition on the scalp of the subjects.
[0041] Example 1: Ms. Liu, female, 46 years old, with fine and soft hair, experienced hair loss on the top of her head. After using the hair growth composition for 3 months, her hair loss significantly decreased, and her parting on the top of her head narrowed. Figure 1 ) Example 2: Ms. Cui, female, 40 years old, had a thinning hairline on the side of her forehead. After using the hair growth composition for 2 months, hair began to grow in the thinning areas. Figure 2 ) Example 3: Mr. Jiang, male, 54 years old, had thinning hair on the back of his head and excessive scalp oil. After using the hair growth composition for 3 months, his hair loss significantly decreased, and hair began to grow in the balding areas. Figure 3 ) Comparative Experiment Example 1: 1. Experimenters: 15 participants with hair loss were selected for the trial.
[0042] 2. The experimental results showed that the hair growth composition had a relatively insignificant effect on the scalp of the subjects.
[0043] Example 4: Ms. Fu, female, 35 years old, with medium to thick hair and slight hair loss on the top of her head. After using the hair growth composition in Comparative Example 1 for 3 months, her hair loss did not decrease significantly, and there was no significant change in her parting on the top of her head. Figure 4 ) Example 5: Mr. Wang, male, 48 years old, with fine, soft, and sparse hair, excessive scalp oil secretion, and significant hair loss. After using the hair growth composition in Comparative Example 1 for 3 months, there was no significant improvement in his hair loss. Figure 5 ).
Claims
1. A hair growth composition comprising or consisting of the following components: Quinoa seed extract, bamboo shoot extract, kudzu root extract, arborvitae leaf extract, ginseng extract, astragalus extract, fleeceflower root extract, pine needle extract, ginger root extract, privet fruit extract, ginkgo leaf extract, fig leaf extract, rosemary leaf extract, houttuynia cordata extract, and ethanol.
2. The hair growth composition according to claim 1, characterized in that, The weight proportions of each component are as follows: The ingredients include: 25-45 parts of Quinoa seed extract, 5-25 parts of Bamboo shoot extract, 0.1-1.5 parts of Pueraria lobata root extract, 1-5 parts of Platycladus orientalis leaf extract, 0.5-5.5 parts of Ginseng extract, 0.1-1 part of Astragalus membranaceus extract, 2-4 parts of Polygonum multiflorum extract, 1-5 parts of Pine needle extract, 0.5-5 parts of Ginger root extract, 0.5-3 parts of Ligustrum lucidum extract, 1-5 parts of Ginkgo biloba leaf extract, 0.1-2 parts of Fig leaf extract, 1-5 parts of Rosemary leaf extract, 1-10 parts of Houttuynia cordata extract, and 10-50 parts of ethanol.
3. The hair growth composition according to claim 2, characterized in that, The weight proportions of each component are as follows: 38-42 parts of Quinoa seed extract, 15-24 parts of Bamboo shoot extract, 0.6-1.2 parts of Pueraria lobata root extract, 3.5-4.5 parts of Platycladus orientalis leaf extract, 4.2-5.2 parts of Ginseng extract, 0.3-0.8 parts of Astragalus membranaceus extract, 1-3 parts of Polygonum multiflorum extract, 3.5-4.5 parts of Pine needle extract, 1-3 parts of Zingiber officinale root extract, 1.5-2.5 parts of Ligustrum lucidum extract, 2-3 parts of Ginkgo biloba leaf extract, 0.5-1.5 parts of Fig leaf extract, 2-4 parts of Rosemary leaf extract, 3-8 parts of Houttuynia cordata extract, and 15-25 parts of ethanol.
4. The hair growth composition according to claim 3, characterized in that, The weight proportions of each component are as follows: 40 parts of Quinoa seed extract, 20 parts of Bamboo shoot extract, 1 part of Pueraria lobata root extract, 4 parts of Platycladus orientalis leaf extract, 5 parts of Ginseng extract, 0.5 parts of Astragalus membranaceus extract, 2 parts of Polygonum multiflorum extract, 4 parts of Pine needle extract, 2 parts of Ginger root extract, 2 parts of Ligustrum lucidum extract, 3 parts of Ginkgo biloba leaf extract, 1 part of Fig leaf extract, 3 parts of Rosemary leaf extract, 5 parts of Houttuynia cordata extract, and 20 parts of Ethanol.
5. The hair growth composition according to any one of claims 1-4, characterized in that, The Quinoa seed extract was prepared by the following method: Weigh 25-35 g of dried Quinoa seed bran powder and place it in a beaker. Add 500-700 mL of deionized water, 0.50-0.70 g of 1.5-2.5% cellulase and pectinase, with a mass ratio of cellulase to pectinase of 0.5-1.5:
1. Place the beaker in a water bath for enzymatic extraction. The enzymatic extraction time is 1.5-2.5 h, the enzymatic extraction temperature is 45-51℃, the pH value is 4.5-5.1, and the material-to-liquid ratio is 1:18-22. After enzymatic extraction, inactivate the extract at 80-90℃ for 3-7 min. After inactivation, sonicate at room temperature in an ultrasonic cleaner for 1.5-2.5 h. Then, filter the extract using a vacuum filtration device.
6. The hair growth composition according to any one of claims 1-4, characterized in that, The bamboo shoot extract was prepared by the following method: Weigh 25-35 g of dried bamboo shoot powder and place it in a beaker. Add 375-525 mL of deionized water, 0.50-0.70 g of cellulase and papain at a concentration of 1.5-2.5% (mass ratio of cellulase to papain: 0.5-1.5:1), and place the beaker in a water bath for enzymatic extraction. The enzymatic extraction time is 2.5-3.5 h, the enzymatic extraction temperature is 40-50 ℃, the pH value is 5.2-6.0, and the material-to-liquid ratio is 1:12-18. After enzymatic extraction, inactivate the extract at 82-88 ℃ for 3-7 min, and then filter the extract using a vacuum filtration device.
7. The hair growth composition according to any one of claims 1-4, characterized in that, The Platycladus orientalis leaf extract was prepared by the following method: Weigh 25-35 g of dried arborvitae leaf powder and place it in a beaker. Add 375-525 mL of 45-55% ethanol solution to the beaker. Place the beaker in an ultrasonic cleaner for ultrasonic-assisted extraction. The extraction time is 40-50 min, the material-to-liquid ratio is 1:12-18, and the extraction temperature is 45-55 ℃. After extraction, filter the extract using a vacuum filter and concentrate the extract by vacuum evaporation using a rotary evaporator to concentrate the material-to-liquid ratio to 1:7-8.
8. The hair growth composition according to any one of claims 1-4, characterized in that, The pine needle extract was prepared by the following method: Weigh 25-35 g of dried pine needle powder and place it in a beaker. Add 375-525 mL of deionized water to the beaker and place the beaker in an ultrasonic cleaner for ultrasonic-assisted extraction. The extraction temperature is 45-55℃, the material-to-liquid ratio is 1:12-18, and the extraction time is 1.5-2.5 h. After extraction, filter the extract using a vacuum filtration device.
9. The hair growth composition according to any one of claims 1-4, characterized in that, The preparation method of the fig leaf extract is as follows: Weigh 15-25 g of dried fig leaf powder and place it in a beaker. Add 300-500 mL of 25-35% ethanol solution to the beaker. Place the beaker in an ultrasonic cleaner for ultrasonic extraction at a temperature of 45-55℃, a solid-liquid ratio of 1:15-25, and an extraction time of 35-45 min. After ultrasonic extraction, filter the extract using a vacuum filtration device and concentrate the extract by vacuum evaporation using a rotary evaporator to achieve a solid-liquid ratio of 1:12-16.
10. The hair growth composition according to any one of claims 1-4, characterized in that, The rosemary leaf extract was prepared by the following method: Weigh 25-35 g of dried rosemary leaves and place them in a beaker. Add 500-700 mL of 65-75% ethanol solution to the beaker. Place the beaker in an ultrasonic cleaner for ultrasonic-assisted extraction for 40-50 min at a solid-liquid ratio of 1:15-25. After extraction, filter the extract using a vacuum filtration device and concentrate it by vacuum evaporation using a rotary evaporator until the solid-liquid ratio is 1:4-8.