Traditional Chinese medicine composition for treating burns and scalds as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention relates to a traditional Chinese medicine composition for treating burns and scalds as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition for treating burns and scalds is prepared from the following raw materials in parts by weight: 15-25 parts of rheum officinale, 15-25 parts of golden cypress, 15-25 parts of sanguisorba officinalis and 8-15 parts of borneol. The traditional Chinese medicine composition for treating burns and scalds is simple in formula and good in treatment effect on burns and scalds, the treatment effective rate reaches 90% or above, and a new means is provided for treating burns and scalds.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating burns and scalds and a preparation method and application thereof. BACKGROUND

[0002] Burns and scalds are common accidental injuries in daily life, mainly caused by heat (such as flame, hot liquid, steam, high-temperature solid, etc.) acting on the skin and mucous membrane tissues of the human body, which can cause different degrees of tissue damage, and can even involve subcutaneous tissue, muscle, bone and even internal organs. Burns and scalds not only bring severe pain to patients, but also can cause complications such as infection, scar hyperplasia and dysfunction, seriously affecting the quality of life of patients, and even threatening life safety.

[0003] At present, the methods for treating burns and scalds in clinical practice mainly include Western medicine treatment and traditional Chinese medicine treatment. Western medicine treatment usually adopts comprehensive measures such as debridement, anti-infection, fluid replacement and pain relief. For patients with severe burns and scalds, surgical treatment such as skin grafting may be needed. However, Western medicine treatment has some limitations, for example, some drugs may cause allergic reactions or gastrointestinal discomfort and other side effects; surgical treatment has high risk, long postoperative recovery time, and may leave obvious scars.

[0004] Traditional Chinese medicine has a long history and rich experience in treating burns and scalds. Traditional Chinese medicine believes that burns and scalds belong to the invasion of "fire toxin" to the skin, leading to blood stasis and heat toxin accumulation. The treatment principle is mainly to clear heat and resolve toxin, cool blood and activate blood, relieve swelling and pain, and promote wound healing. Traditional Chinese medicine has various methods for treating burns and scalds, including oral administration of traditional Chinese medicine, external use of ointment, medicinal bath, etc. Among them, external use of traditional Chinese medicine can directly act on the wound, quickly relieve pain, reduce inflammatory reaction and promote wound healing, and has attracted widespread attention.

[0005] However, the existing traditional Chinese medicine preparations for treating burns and scalds have some shortcomings. Some preparations have complex formula, numerous drug components, complicated preparation process and high cost; the curative effect of some preparations is unstable, and the treatment effect is greatly different for different types and degrees of burns and scalds; some preparations have strong irritation and are easy to cause allergic reactions, which limits their wide application in clinical practice.

[0006] Therefore, it is of great clinical significance and application value to develop a traditional Chinese medicine composition for treating burns and scalds with simple formula, definite curative effect and high safety. SUMMARY

[0007] In order to solve the above problems, the present application provides a traditional Chinese medicine composition for treating burns and scalds and a preparation method and application thereof.

[0008] In a first aspect, the present application provides a traditional Chinese medicine composition for treating burns and scalds, which is composed of the following ingredients in parts by weight: Rhubarb 15-25 parts, Cortex Phellodendri 15-25 parts, Radix Sanguisorbae 15-25 parts, and Borneolum Syntheticum 8-15 parts.

[0009] Further, the traditional Chinese medicine composition for treating burns and scalds is composed of the following ingredients in parts by weight: Rhubarb 20 parts, Cortex Phellodendri 20 parts, Radix Sanguisorbae 20 parts, and Borneolum Syntheticum 10 parts.

[0010] Further, the traditional Chinese medicine composition for treating burns and scalds is composed of the following ingredients in parts by weight: Rhubarb 15 parts, Cortex Phellodendri 25 parts, Radix Sanguisorbae 25 parts, and Borneolum Syntheticum 15 parts.

[0011] Further, the traditional Chinese medicine composition for treating burns and scalds is composed of the following ingredients in parts by weight: Rhubarb 25 parts, Cortex Phellodendri 15 parts, Radix Sanguisorbae 15 parts, and Borneolum Syntheticum 8 parts.

[0012] In a second aspect, the present application provides a preparation method of the traditional Chinese medicine composition for treating burns and scalds according to any one of the first aspect, which comprises the following steps: mixing and crushing Rhubarb, Cortex Phellodendri, and Radix Sanguisorbae to obtain a traditional Chinese medicine powder; immersing the traditional Chinese medicine powder in alcohol with a weight of 5-10 times that of the traditional Chinese medicine powder for 15-20 days, filtering, adding crushed Borneolum Syntheticum, and obtaining the traditional Chinese medicine composition.

[0013] Further, the particle size of the traditional Chinese medicine powder is 100-200 meshes.

[0014] In a third aspect, the present application provides an application of the traditional Chinese medicine composition for treating burns and scalds according to any one of the first aspect in preparing a medicine for treating burns.

[0015] Further, the dosage form of the medicine for treating burns includes a solvent.

[0016] Compared with the prior art, the above technical solution provided by the embodiments of the present application has at least the following advantages: The embodiments of the present application provide a traditional Chinese medicine composition for treating burns and scalds, a preparation method and an application thereof. The present application provides a traditional Chinese medicine composition for treating burns and scalds, which has a simple formula, good curative effect on treating burns and scalds, and a high treatment efficiency of more than 90%, and provides a new means for treating burns and scalds. BRIEF DESCRIPTION OF DRAWINGS

[0017] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with the invention and, together with the description, serve to explain the principles of the invention.

[0018] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a typical case in the present invention. Figure 1 .

[0020] Figure 2 This is a typical case in the present invention. Figure 2 .

[0021] Figure 3 This is a typical case in the present invention. Figure 3 .

[0022] Figure 4 This is a typical case in the present invention. Figure 4 .

[0023] Figure 5 This is a typical case in the present invention. Figure 1 . Detailed Implementation

[0024] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0025] Unless otherwise specified, all raw materials, reagents, instruments and equipment used in this invention can be purchased from the market or prepared by existing methods.

[0026] It should be noted that, unless otherwise specified or described, the raw materials involved in the traditional Chinese medicine composition for treating burns and scalds and its preparation method provided in the embodiments of the present invention can be directly made from commercially available products or by using existing publicly disclosed preparation methods; at the same time, unless otherwise specified or described, the steps and parameters involved can be carried out according to the existing processing technology of traditional Chinese medicine composition for treating burns and scalds or directly using existing equipment, and will not be described in detail in this document.

[0027] The present invention will be further illustrated below with reference to specific embodiments. It should be understood that these embodiments are for illustrative purposes only and are not intended to limit the scope of the invention. Experimental methods in the following embodiments, unless otherwise specified, are generally performed according to national standards. If no corresponding national standard exists, then generally accepted international standards, conventional conditions, or conditions recommended by the manufacturer are followed.

[0028] Example 1 This example provides a traditional Chinese medicine composition for treating burns and scalds, which, by weight, consists of the following raw materials: 20 parts rhubarb, 20 parts phellodendron bark, 20 parts burnet root, and 10 parts borneol.

[0029] The preparation method of the above-mentioned traditional Chinese medicine composition for treating burns includes the following steps: Rhubarb, Phellodendron bark, and Sanguisorba officinalis are mixed, pulverized, and passed through a 150-mesh sieve to obtain Chinese medicine powder; The herbal powder was soaked in alcohol at a ratio of 8 times its weight for 18 days, then filtered, and pulverized borneol was added to obtain the herbal composition.

[0030] The herbal composition obtained in this case was applied to the wound using a spray bottle 7-8 times daily. Clinical application results showed an effectiveness rate of 99.1%.

[0031] Example 2 This example provides a traditional Chinese medicine composition for treating burns and scalds, which, by weight, consists of the following raw materials: 15 parts rhubarb, 25 parts phellodendron bark, 25 parts burnet root, and 15 parts borneol.

[0032] The preparation method of the above-mentioned traditional Chinese medicine composition for treating burns includes the following steps: Rhubarb, Phellodendron bark, and Sanguisorba officinalis are mixed, pulverized, and passed through a 150-mesh sieve to obtain Chinese medicine powder; The herbal powder was soaked in alcohol at a ratio of 5 times its weight for 20 days, then filtered, and pulverized borneol was added to obtain the herbal composition.

[0033] The herbal composition obtained in this case was applied to the wound using a spray bottle 7-8 times daily. Clinical application results showed an effectiveness rate of 86.5%.

[0034] Example 3 This example provides a traditional Chinese medicine composition for treating burns and scalds, which, by weight, consists of the following raw materials: 25 parts rhubarb, 15 parts phellodendron bark, 15 parts burnet root, and 8 parts borneol.

[0035] The preparation method of the above-mentioned traditional Chinese medicine composition for treating burns includes the following steps: Rhubarb, Phellodendron bark, and Sanguisorba officinalis are mixed, pulverized, and passed through a 150-mesh sieve to obtain Chinese medicine powder; The herbal powder was soaked in alcohol at a ratio of 10 times its weight for 15 days, then filtered, and pulverized borneol was added to obtain the herbal composition.

[0036] The herbal composition obtained in this case was applied to the wound using a spray bottle 7-8 times daily. Clinical application results showed an effective rate of 90.8%.

[0037] The following are some typical cases treated using Example 1: 1. For example Figure 2 As shown, the arm suffered second-degree burns, with pain and blisters. After the first day of medication, the pain was significantly reduced, and the peeling skin showed signs of healing. After 7 days of treatment, new flesh had regenerated, and the old skin had detached. Figure 3 As shown.

[0038] 2. For example Figure 4 As shown, after 20 days of treatment at a large hospital, the wound failed to heal and oozed fluid. On the first day of treatment, the burn had reached deep second-degree. The results after 10 days of treatment were as follows: Figure 5 As shown, the wound has significantly closed, and the exudate has decreased considerably; continued treatment for 20 days will yield similar results. ​ As shown, only the deeper wounds had not scabbed over; the others had mostly scabbed over and the scabs had fallen off, with new skin regenerating. In this case, the treatment time was prolonged due to the delayed treatment.

[0039] Various embodiments of the present invention may exist in the form of a range; it should be understood that the description in the form of a range is merely for convenience and brevity and should not be construed as a hard limitation on the scope of the invention; therefore, it should be considered that the range description has specifically disclosed all possible subranges and single numerical values ​​within that range. For example, it should be considered that the range description from 1 to 6 has specifically disclosed subranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., and single numbers within the range, such as 1, 2, 3, 4, 5, and 6, regardless of the range. Furthermore, whenever a numerical range is referred to herein, it means including any referenced number (fraction or integer) within the range referred to.

[0040] The above description is merely a specific embodiment of the present invention, enabling those skilled in the art to understand or implement the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features claimed herein.

Claims

1. A traditional Chinese medicine composition for treating burns, characterized in that, The traditional Chinese medicine composition for treating burns and scalds, by weight, consists of the following raw materials: 15-25 parts rhubarb, 15-25 parts phellodendron bark, 15-25 parts burnet root, and 8-15 parts borneol.

2. The traditional Chinese medicine composition for treating burns and scalds according to claim 1, characterized in that, The traditional Chinese medicine composition for treating burns and scalds, by weight, consists of the following raw materials: 20 parts rhubarb, 20 parts phellodendron bark, 20 parts burnet root, and 10 parts borneol.

3. The traditional Chinese medicine composition for treating burns and scalds according to claim 1, characterized in that, The traditional Chinese medicine composition for treating burns and scalds, by weight, consists of the following raw materials: 15 parts rhubarb, 25 parts phellodendron bark, 25 parts burnet root, and 15 parts borneol.

4. The traditional Chinese medicine composition for treating burns according to claim 1, characterized in that, The traditional Chinese medicine composition for treating burns and scalds, by weight, consists of the following raw materials: 25 parts rhubarb, 15 parts phellodendron bark, 15 parts burnet root, and 8 parts borneol.

5. A method for preparing a traditional Chinese medicine composition for treating burns as described in any one of claims 1 to 4, characterized in that, The preparation method includes the following steps: Rhubarb, Phellodendron bark, and Sanguisorba officinalis are mixed and pulverized to obtain traditional Chinese medicine powder; Add alcohol at a ratio of 5 to 10 times the weight of the Chinese herbal powder to the powder, soak for 15 to 20 days, then filter, add pulverized borneol, and obtain the Chinese herbal composition.

6. The method for preparing the traditional Chinese medicine composition for treating burns according to claim 5, characterized in that, The particle size of the Chinese herbal powder is 100-200 mesh.

7. The use of a traditional Chinese medicine composition for treating burns according to any one of claims 1 to 4 in the preparation of a burn treatment drug.

8. The application according to claim 7, characterized in that, The dosage form of the burn treatment drug includes a solvent.

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