Biodegradable scrub particles and skin cleansing compositions comprising same

Abstract

The present invention relates to biodegradable scrub particles and a skin cleansing composition comprising the same, wherein the biodegradable scrub particles comprise a polyhydroxyalkanoate (PHA).

Description

Technical Field

[0001] This disclosure relates to biodegradable scrub particles comprising a biodegradable polymer, and to skin cleansing compositions comprising the biodegradable scrub particles. Background Technology

[0002] Cleansing products typically contain scrub agents for various reasons, including removing dirt, waste (e.g., sebum, dead skin cells, etc.), or cosmetic residues on the skin. Such scrub agents consist of particles made from petroleum-based synthetic resins such as polyethylene, polypropylene, and polystyrene. However, petroleum-based synthetic resins can form microplastics, which have a negative impact on the environment. Therefore, a global trend is to ban the sale of cleansing products containing solid synthetic resin particles (microplastics) of 5 mm or smaller for skin cleansing purposes. Consequently, the demand for cleansing products containing particles made from natural or biodegradable raw materials is increasing.

[0003] To address these needs, cleaning products containing natural raw material particles (such as chitin from crustaceans or walnut shells) have been developed; however, this presents the challenge of high production costs. Furthermore, the relatively rough surface of these natural raw material particles can cause skin damage when using such products.

[0004] Therefore, there is a need to develop a cleaning product that is less irritating to the skin, has excellent skin-cleansing ability, and is also biodegradable and environmentally friendly. Summary of the Invention

[0005] Technical issues

[0006] To address the aforementioned problems of the prior art, one object of this disclosure is to provide biodegradable exfoliating particles and a skin cleansing composition comprising the biodegradable exfoliating particles, which have excellent skin cleansing ability, are low in skin irritation, and are also biodegradable and environmentally friendly.

[0007] Technical solution

[0008] To achieve the above objectives, this disclosure provides biodegradable abrasive particles comprising polyhydroxyalkanoate (PHA) containing 0.1 to 50% by weight of repeating units derived from 4-hydroxybutyrate (4-HB) based on the total weight of the polyhydroxyalkanoate (PHA), wherein the particle size (D) of the biodegradable abrasive particles is... 50 The range is 10 to 1,000 μm.

[0009] According to another embodiment of this disclosure, the polyhydroxyalkanoate (PHA) may further comprise a repeating unit derived from at least one monomer selected from the group consisting of: 2-hydroxybutyrate (2-HB), 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 3-hydroxyheptanoate (3-Hhep), 3-hydroxyoctanoate (3-HO), 3-hydroxynonanoate (3-HN), 3-hydroxydecanoate (3-HD), 3-hydroxydodecanoate (3-HDd), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH).

[0010] According to another embodiment of this disclosure, the polyhydroxyalkanoate may further comprise repeating units derived from 3-hydroxybutyrate (3-HB).

[0011] According to another embodiment of this disclosure, the particle size (D) of the biodegradable abrasive particles 50 The range is 10 to 800 μm.

[0012] According to another embodiment of this disclosure, the content of repeating units derived from 4-hydroxybutyrate (4-HB) can be from 1 to 10 by weight based on the total weight of polyhydroxyalkanoate (PHA).

[0013] In order to achieve the above objectives, this disclosure provides a skin cleansing composition comprising biodegradable exfoliating particles; a surfactant; and a polyol.

[0014] According to one embodiment of this disclosure, the content of biodegradable exfoliating particles can be from 0.5 to 30% by weight based on the total weight of the skin cleansing composition.

[0015] According to another embodiment of this disclosure, the content of surfactant may be 10 to 40% by weight based on the total weight of the skin cleansing composition, and the content of polyol may be 1 to 15% by weight based on the total weight of the skin cleansing composition.

[0016] According to another embodiment of this disclosure, the skin cleansing composition may further comprise purified water, wherein the content of biodegradable exfoliating particles may be 0.5 to 20 parts by weight relative to 100 parts by weight of purified water.

[0017] According to another embodiment of this disclosure, the skin cleansing composition may further comprise purified water, wherein the content of surfactant may be 20 to 60 parts by weight relative to 100 parts by weight of purified water, and the content of polyol may be 0.5 to 25 parts by weight relative to 100 parts by weight of purified water.

[0018] According to another embodiment of this disclosure, the surfactant may comprise at least one selected from the group consisting of: cocamidopropyl betaine, potassium cocoyl glycinate, sodium oleate, stearic acid, myristic acid, lauric acid, glyceryl stearate, sodium lauryl ether sulfate, sodium cocoyl sulfate, sodium cocoyl ethanesulfonate, sodium lauroyl methyl ethanesulfonate, sodium lauroyl glutamate, sodium lauroyl aspartate, polysorbate 60, polysorbate 80, lauryl hydroxysulfonate betaine, sorbitol polyether-30 tetraoleate, sucrose laurate, polyglycerol-10 oleate, polyglycerol-10 dioleate, polyglycerol-2 sesquioctanoate, and lauryl ether-4.

[0019] According to another embodiment of this disclosure, the polyol may comprise at least one selected from the group consisting of glycerol, 1,3-butanediol, dipropylene glycol, propylene glycol, polyethylene glycol, and 1,2-hexanediol.

[0020] According to another embodiment of this disclosure, the skin cleansing composition may further comprise at least one selected from the group consisting of: moisturizers, emollients, thickeners, preservatives, neutralizers, acidity regulators, and fragrances.

[0021] According to another embodiment of this disclosure, the skin cleansing composition can be used to cleanse the face, body, or scalp.

[0022] Beneficial effects of the present invention

[0023] The biodegradable exfoliating particles of this disclosure contain polyhydroxyalkanoates (PHA), and their particle size is controlled within a specific range; therefore, when the skin is cleansed with a skin cleansing composition containing these particles, the skin cleansing ability to remove skin impurities and waste (e.g., sebum, dead skin cells, etc.) or residual cosmetics is excellent, thereby making the skin texture smooth and maintaining an ideal skin condition.

[0024] Furthermore, biodegradable exfoliating particles containing polyhydroxyalkanoates (PHA) have a smooth and uniform surface, allowing them to be rolled smoothly without damaging the skin. Therefore, when cleansing the skin with a skin-cleansing composition containing biodegradable exfoliating particles, it is minimally irritating and leaves the skin feeling soft after cleansing.

[0025] Furthermore, the polyhydroxyalkanoates (PHAs) contained in the biodegradable abrasive particles have excellent biodegradability in soil and / or ocean; therefore, the biodegradable abrasive particles according to this disclosure can be environmentally friendly without causing microplastic problems.

[0026] Therefore, the skin cleansing composition containing biodegradable exfoliating particles according to the present disclosure can be effectively applied to cleansing products (cosmetics) for cleansing the face, body or scalp (hair), and it can also be effectively used to protect the environment. Detailed Implementation

[0027] This disclosure will be described in detail below. This disclosure is not limited to the forms given below, but can be modified in many ways without altering the spirit of this disclosure.

[0028] In this specification, the term "comprising" is intended to specify a particular feature, area, step, process, element, and / or component. It does not exclude the presence or addition of any other feature, area, step, process, element, and / or component unless specifically stated to the contrary.

[0029] All figures and expressions used in this document relating to component quantities, reaction conditions, etc., should be understood as being modified by the term “about” unless otherwise stated.

[0030] Biodegradable abrasive particles

[0031] The biodegradable abrasive particles (hereinafter referred to as "abrasive particles") according to this disclosure contain polyhydroxyalkanoates (hereinafter referred to as "PHA"), and their particle size is controlled within a specific range. For example, the abrasive particles may be composed of PHA particles, as described in detail below.

[0032] PHA granules are abrasive granules, with particle size (average particle diameter or median particle size; particle size D when the cumulative percentage reaches 50%). 50 The size of PHA particles ranges from 10 to 1000 μm. 50 Within the above range, rolling on the skin proceeds well without damaging the skin, and skin cleansing compositions containing PHA particles can have excellent skin cleansing ability with minimal skin irritation. In particular, the size (D) of the PHA particles... 50 The value can be 10 to 950 μm, 10 to 900 μm, 10 to 850 μm, 10 to 800 μm, 20 to 950 μm, 30 to 900 μm, 40 to 850 μm, 50 to 800 μm, 60 to 750 μm, 70 to 700 μm, 80 to 650 μm, 85 to 650 μm, 90 to 600 μm, 95 to 550 μm, 100 to 500 μm, 150 to 450 μm, or 200 to 400 μm, but is not limited to these values.

[0033] For example, when a skin cleansing composition containing PHA particles as exfoliating particles is applied to a facial cleansing product, the size (D) of the PHA particles... 50The size of the PHA particles can be 10 to 400 μm, 15 to 380 μm, 20 to 360 μm, 25 to 350 μm, 30 to 340 μm, 35 to 330 μm, 40 to 320 μm, 45 to 310 μm, or 50 to 300 μm, but is not limited thereto. Furthermore, when a skin cleansing composition containing PHA particles as exfoliating particles is applied to a scalp (hair) and / or body cleansing product, the size (D) of the PHA particles... 50 The value can be 10 to 900 μm, 30 to 880 μm, 50 to 860 μm, 70 to 840 μm, 90 to 820 μm, 100 to 800 μm, 150 to 750 μm, 180 to 700 μm, 200 to 600 μm, or 200 to 550 μm, but is not limited to these values.

[0034] PHA granules can be obtained by granulating PHA using conventional methods; then the granulated PHA is fed into a circular vibrating separator for sorting.

[0035] PHA is a natural polyester polymer that accumulates within microbial cells and can be completely decomposed into carbon dioxide, water, organic waste, etc., in soil and / or oceans; therefore, PHA can exhibit excellent biodegradability without producing microplastics. Consequently, the abrasive particles according to this disclosure can possess excellent biodegradability and environmental friendliness because they contain such PHA.

[0036] PHA can be obtained by disrupting cells using mechanical or physical methods, or by disrupting cells using non-mechanical or chemical methods. Specifically, PHA can be a copolymer obtained through an enzymatic polymerization process of one or more monomers within living microbial cells.

[0037] PHA may comprise repeating units derived from at least one (e.g., two or more) monomers selected from the group consisting of: 2-hydroxybutyrate (2-HB), 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 3-hydroxyheptanoate (3-HHep), 3-hydroxyoctanoate (3-HO), 3-hydroxynonanoate (3-HN), 3-hydroxydecanoate (3-HD), 3-hydroxydodecanoate (3-HDd), 4-hydroxybutyric acid (4-HB), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH). Specifically, the PHA may comprise repeating units derived from at least one (e.g., two or more) monomers selected from the group consisting of: 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 4-hydroxybutyrate (4-HB), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH). In such cases, one or more repeating units derived from at least one monomer may be randomly distributed.

[0038] More specifically, PHA comprises repeating units derived from 4-hydroxybutyrate (4-HB), and may also comprise one, two, three, four, five, six or more repeating units derived from one or more monomers other than 4-hydroxybutyrate (4-HB). Because PHA comprises repeating units derived from 4-hydroxybutyrate (4-HB), the performance of the exfoliating particles can be optimized. Therefore, skin cleansing compositions suitable for a variety of purposes can be provided.

[0039] PHAs can be classified as crystalline PHAs (cPHA), semi-crystalline PHAs (scPHA), or amorphous PHAs (aPHA), depending on the type of monomer and the content of repeating units derived from the monomer. For example, PHAs can be classified as cPHA, scPHA, or aPHA because their crystallinity is controlled by the content of repeating units derived from 4-hydroxybutyrate (4-HB).

[0040] Specifically, PHA may contain repeating units derived from 3-hydroxybutyrate (3-HB) (hereinafter referred to as "3-HB repeating units") and repeating units derived from 4-hydroxybutyrate (4-HB) (hereinafter referred to as "4-HB repeating units"). That is, PHA may be a poly(3-hydroxybutyrate-co-4-hydroxybutyrate; P3HB-co-4HB) copolymer containing both 3-HB and 4-HB repeating units. Because PHA contains both 3-HB and 4-HB repeating units, the mechanical strength, heat resistance, oil resistance, etc., of the exfoliating particles are ensured, and even when the skin cleansing composition containing exfoliating particles is used for multiple purposes (e.g., face, body, or scalp), the skin cleansing ability is guaranteed.

[0041] Controlling the content of 4-HB repeating units contained in the PHA can be important in order to provide exfoliating particles and skin cleansing compositions having the desired properties as disclosed herein. Specifically, the content of 4-HB repeating units contained in the PHA can be from 0.1% to 50% by weight based on the total weight of the PHA. More specifically, the content of the 4-HB repeating unit, based on the total weight of PHA, can be 0.1 to 45 wt%, 0.2 to 43 wt%, 0.3 to 40 wt%, 0.3 to 38 wt%, 0.3 to 35 wt%, 0.4 to 32 wt%, 0.4 to 30 wt%, 0.5 to 28 wt%, 0.5 to 25 wt%, 0.6 to 20 wt%, 0.6 to 18 wt%, 0.7 to 16 wt%, 0.8 to 15 wt%, 1 to 15 wt%, 1 to 13 wt%, 1 to 10 wt%, 1.5 to 10 wt%, 1.8 to 10 wt%, 2 to 10 wt%, 2.5 to 9.5 wt%, 3 to 9 wt%, 3.5 to 8 wt%, 4 to 7 wt%, or 5 to 6.5 wt%, but is not limited thereto. When the content of the 4-HB repeating unit is within the above range, the biodegradability of the abrasive particles can be further improved, while the formulation stability and mechanical strength of the abrasive particles can be maintained at the required levels.

[0042] The weight-average molecular weight (Mw) of PHA can be from 100,000 to 800,000 g / mol, 130,000 to 780,000 g / mol, 150,000 to 750,000 g / mol, 200,000 to 700,000 g / mol, 250,000 to 650,000 g / mol, 280,000 to 600,000 g / mol, 300,000 to 550,000 g / mol, or 320,000 to 500,000 g / mol, but is not limited to these.

[0043] Skin cleansing composition

[0044] The skin cleansing composition according to this disclosure comprises exfoliating particles containing PHA, wherein the particle size is controlled within a specific range. Specifically, the skin cleansing composition according to this disclosure comprises biodegradable exfoliating particles containing PHA; a surfactant; and a polyol, optionally further comprising purified water and / or additives, as described in detail below.

[0045] The biodegradable exfoliating particles contained in the skin cleansing composition of this disclosure comprise the aforementioned PHA. Specifically, the biodegradable exfoliating particles have substantially the same composition and properties as the aforementioned exfoliating particles. Because the skin cleansing composition of this disclosure comprises such biodegradable exfoliating particles, the skin cleansing composition can possess excellent biodegradability, skin cleansing ability, and formulation stability, and exhibits low skin irritation.

[0046] There is no particular limitation on the content of biodegradable exfoliating particles, but the total weight of the exfoliating particles based on the skin cleansing composition can be from 0.5 to 30% by weight. In particular, the content of biodegradable exfoliating particles based on the total weight of the skin cleansing composition can be 0.5 to 25% by weight, 0.5 to 23% by weight, 0.5 to 20% by weight, 0.6 to 18% by weight, 0.6 to 15% by weight, 0.7 to 13% by weight, 0.8 to 12% by weight, 1% to 11% by weight, 2% to 10% by weight, or 3% to 10% by weight, but is not limited thereto.

[0047] In this document, when the skin cleansing composition further comprises purified water, the content of biodegradable exfoliating particles may be 0.5 to 20 parts by weight relative to 100 parts by weight of purified water. Specifically, the content of biodegradable exfoliating particles relative to 100 parts by weight of purified water may be 1 to 18 parts by weight, 1.5 to 17 parts by weight, 2 to 16 parts by weight, 2.5 to 15 parts by weight, 3 to 14 parts by weight, 3.5 to 13 parts by weight, 4 to 12 parts by weight, 4.5 to 11 parts by weight, or 5 to 10 parts by weight, but is not limited thereto.

[0048] When the content of biodegradable exfoliating particles is within the above range, a skin cleansing composition with excellent skin cleansing ability, low skin irritation and guaranteed formulation stability can be provided.

[0049] The surfactant contained in the skin cleansing composition according to this disclosure is an ingredient that improves the skin cleansing ability of the skin cleansing composition, while allowing the skin cleansing composition to be easily rinsed off with water.

[0050] There are no particular limitations on the surfactant, but it may contain at least one selected from the group consisting of: cocamidopropyl betaine, potassium cocoyl glycinate, sodium oleate, stearic acid, myristic acid, lauric acid, glyceryl stearate, sodium lauryl ether sulfate, sodium cocoyl sulfate, sodium cocoyl ethanesulfonate, sodium lauroyl methyl ethanesulfonate, sodium lauroyl glutamate, sodium lauroyl aspartate, polysorbate 60, polysorbate 80, lauryl hydroxysulfonate betaine, sorbitol polyether-30 tetraoleate, sucrose laurate, polyglycerol-10 oleate, polyglycerol-10 dioleate, polyglycerol-2 sesquioctanoate, and lauryl ether-4. Specifically, the surfactant may contain two or more (specifically, three or more, four or more, five or more) selected from the group consisting of: cocamidopropyl betaine, potassium cocoyl glycinate, sodium oleate, stearic acid, myristic acid, lauric acid, glyceryl stearate, sodium lauryl sulfate, lauryl hydroxysulfonate betaine, and lauryl alcohol polyether-4.

[0051] There is no particular limitation on the content of surfactants, but their total weight based on the skin cleansing composition can be 10 to 40% by weight. In particular, the content of surfactants based on the total weight of the skin cleansing composition can be 12 to 40% by weight, 13 to 38% by weight, 14 to 36% by weight, 15 to 35% by weight, 16 to 33% by weight, 17 to 32% by weight, 18 to 31% by weight, 19 to 30% by weight, 20 to 28% by weight, or 22 to 27% by weight, but is not limited thereto.

[0052] Furthermore, when the skin cleansing composition also contains purified water, the surfactant content relative to 100 parts by weight of purified water can be 20 to 60 parts by weight. Specifically, the surfactant content relative to 100 parts by weight of purified water can be 20 to 58 parts by weight, 22 to 55 parts by weight, 25 to 53 parts by weight, 28 to 50 parts by weight, 30 to 48 parts by weight, 32 to 45 parts by weight, 33 to 43 parts by weight, 34 to 42 parts by weight, or 35 to 40 parts by weight, but is not limited thereto.

[0053] When the surfactant content is within the above range, a skin cleansing composition can be provided, which ensures skin cleansing ability and rinsing stability, and minimizes skin irritation.

[0054] The polyol contained in the skin cleansing composition of this disclosure is an ingredient that ensures the formulation stability of the skin cleansing composition while enhancing the skin's moisturizing ability.

[0055] There are no particular limitations on the polyol, but it may contain at least one selected from the group consisting of glycerol, 1,3-butanediol, dipropylene glycol, propylene glycol, polyethylene glycol, and 1,2-hexanediol. In particular, the polyol may include glycerol, which is economical and has excellent moisturizing properties.

[0056] There is no particular limitation on the content of polyols, but their total weight based on the skin cleansing composition can be from 1 to 15% by weight. In particular, the content of polyols based on the total weight of the skin cleansing composition can be 1.5 to 15% by weight, 2 to 14.5% by weight, 3 to 14% by weight, 4 to 13.5% by weight, 5 to 13% by weight, 6 to 12.5% ​​by weight, 7 to 12% by weight, 7.5 to 11.5% by weight, 8 to 11% by weight, or 8.5 to 11% by weight, but is not limited thereto.

[0057] Furthermore, when the skin cleansing composition also contains purified water, the content of polyols relative to 100 parts by weight of purified water can be from 0.5 to 25 parts by weight. Specifically, the content of polyols relative to 100 parts by weight of purified water can be from 0.8 to 24 parts by weight, 1 to 22 parts by weight, 1.5 to 20 parts by weight, 1.8 to 18 parts by weight, 2 to 17 parts by weight, 2.2 to 16 parts by weight, 2.4 to 15 parts by weight, 2.6 to 14 parts by weight, or 2.8 to 13.5 parts by weight, but is not limited thereto.

[0058] When the content of polyols is within the above range, a skin cleansing composition with stable skin moisturizing ability and formulation stability can be provided.

[0059] The skin cleansing composition according to this disclosure may further contain purified water to control viscosity and ensure formulation stability. There are no particular limitations on the purified water, as long as it is a known type of purified water (e.g., distilled water, deionized water, pure water, etc.).

[0060] As needed, the skin cleansing composition according to this disclosure may further comprise at least one additive selected from the group consisting of: moisturizers, emollients, thickeners, preservatives, neutralizers, acidity regulators, and fragrances.

[0061] The skin cleansing composition disclosed herein also includes a moisturizer that is an ingredient capable of supplying moisture to the skin.

[0062] The skin cleansing composition according to this disclosure also includes an emollient that imparts softness and soothes the skin. There are no particular limitations on the emollient, but it may contain at least one selected from the group consisting of: natural plant oils, ester-based oils, hydrocarbon-based oils, higher alcohols, and silicone oils.

[0063] The skin cleansing composition according to this disclosure also includes a thickener, which is a component that increases the viscosity of the skin cleansing composition. There are no particular limitations on the thickener, but it may contain at least one selected from the group consisting of: polyquaternium-10, carbomer, sodium chloride, methylcellulose, carboxymethylcellulose, carboxymethyl hydroxyguanine, hydroxymethylcellulose, hydroxyethylcellulose, sodium acryloyl dimethyl taurate / VP crosspolymer, ammonium acryloyl dimethyl taurate / VP copolymer, hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, polyacrylate crosspolymer-6, stearic acid, carrageenan, xanthan gum, gellan gum, cellulose gum, and bentonite.

[0064] The preservatives included in the skin cleansing compositions according to this disclosure are ingredients that increase the storage stability of the skin cleansing compositions. There are no particular limitations on the preservatives, but they may include at least one selected from the group consisting of: phenoxyethanol, ethylhexylglycerin, octyl glycol, chlorophenylglycerin ether, and sodium benzoate.

[0065] The neutralizing agent also included in the skin cleansing composition according to this disclosure is an ingredient that interacts with the preservatives contained in the skin cleansing composition to increase the safety of the skin cleansing composition during its use. There are no particular limitations on the neutralizing agent, but it may include at least one selected from the group consisting of: potassium hydroxide, sodium hydroxide, calcium hydroxide, triethanolamine, trolamine, and aminomethylpropanol.

[0066] The skin cleansing composition disclosed herein also includes an acidity regulator, which is a component for adjusting the pH of the skin cleansing composition. There are no particular limitations on the acidity regulator, but it may contain at least one selected from the group consisting of: citric acid, acetic acid, propionic acid, oxalic acid, glycolic acid, malonic acid, lactic acid, succinic acid, tartaric acid, aspartic acid, maleic acid, glutaric acid, gluconic acid, sorbic acid, benzoic acid, ascorbic acid, and salicylic acid.

[0067] The skin cleansing composition disclosed herein also includes a fragrance, which is a component that imparts a fragrance to the skin cleansing composition.

[0068] The amounts of these additives can be appropriately adjusted within a range that does not impair the desired performance of the skin-cleansing composition.

[0069] Because the skin cleansing composition according to this disclosure contains the above-mentioned ingredients, it ensures formulation stability while exhibiting excellent biodegradability and skin cleansing ability. In particular, because the skin cleansing composition according to this disclosure contains the above-mentioned biodegradable exfoliating particles, it is biodegradable, environmentally friendly, and has low skin irritation, leaving the skin soft after cleansing.

[0070] The skin cleansing compositions according to this disclosure can be used for a variety of purposes. For example, the skin cleansing compositions according to this disclosure can be advantageously applied to cleansing products used for cleansing the face, body, or scalp.

[0071] The method of the present invention

[0072] The present disclosure will be described in detail below with reference to embodiments, but the scope of the present disclosure is not limited to the embodiments.

[0073] [Example 1] Preparation of biodegradable abrasive particles

[0074] Polyhydroxyalkanoate (P3HB-co-4HB; CJ CheilJedang) containing 3-HB repeating units and 4-HB repeating units was granulated using an atomizing pulverizer to prepare powdered polyhydroxyalkanoate. Next, the prepared polyhydroxyalkanoate was fed into a circular vibrating separator and sorted to produce D... 50 Polyhydroxyalkanoate particles of 250 to 350 μm were used as abrasive particles.

[0075] [Example 2] Preparation of biodegradable abrasive particles

[0076] D was prepared using the same procedure as in Example 1. 50 The abrasive particles are 250 to 350 μm polyhydroxyalkanoate particles, the difference being the use of P3HB-co-4HB with a 4-HB repeating unit content of 12% by weight.

[0077] <Preparation of Skin Cleansing Compositions - Shower Gel>

[0078] [Preparation Example 1]

[0079] Step (1): Pour the aqueous phases (raw materials 1 and 2) into a beaker at room temperature. While mixing them using an Agi mixer, slowly add the surfactants (raw materials 3 to 5) over 5 minutes. After the addition is complete, mix them for 10 minutes to obtain a uniform dispersion 1.

[0080] Step (2): At room temperature, slowly add the thickener (raw material 6) and neutralizer (raw material 7) to the dispersion 1 of step (1) over 5 minutes and mix them to obtain a uniform dispersion 2.

[0081] Step (3): At room temperature, slowly add the preservatives (raw materials 8 and 9) to the dispersion 2 of step (2) over 5 minutes and mix them to obtain a uniform dispersion 3.

[0082] Step (4): At room temperature, slowly add the abrasive particles (raw material 10) of Example 1 to the dispersion 3 of Step (3) over 5 minutes and stir them to prepare a transparent gel-like shower gel.

[0083] [Preparation Example 2]

[0084] Shower gel was prepared using the same procedure as in Preparation Example 1, except that the exfoliating particles (raw material 10) of Example 2 were used, and the composition of the shower gel (unit: parts by weight) is shown in Table 1 below.

[0085] [Comparative Preparation Example 1]

[0086] Shower gel was prepared using the same procedure as in Preparation Example 1, except that step (4) of adding the abrasive particles of Example 1 under stirring was omitted, and the composition of the shower gel (unit: parts by weight) is shown in Table 1 below.

[0087] [Table 1]

[0088]

[0089] [Test Example 1] Usability Satisfaction Evaluation

[0090] The usability satisfaction of the shower gels prepared in Preparation Examples 1 and 2, and Comparative Preparation Example 1, was evaluated. The results are shown in Table 2 below. Specifically, 5 g of each shower gel was applied to the arms of 10 women in their 30s and 40s and 10 men in their 30s and 40s, respectively, and rolled 10 times. Subsequently, the arms were moistened with water, rolled 10 times again, and then rinsed off. Usability was scored for each evaluation item, and the average score was calculated.

[0091] *Evaluation Criteria

[0092] Excellent: 5

[0093] Excellent: 4

[0094] Normal: 3

[0095] Difference: 2

[0096] Very poor: 1

[0097] [Table 2]

[0098]

[0099] Referring to Table 2 above, the shower gels containing the biodegradable exfoliating particles according to this disclosure in Preparation Examples 1 and 2 exhibit excellent overall usability satisfaction. In particular, the shower gel of Preparation Example 1 (in which the exfoliating particles containing 10% by weight or less of the 4-HB repeating units contained in the polyhydroxyalkanoate are used) has excellent tumbling feel, superior cleaning ability, and does not dry out the skin, as well as a residue-free finish.

[0100] Meanwhile, the shower gel of Preparation Example 1 (which did not use biodegradable exfoliating particles) had poor overall usability satisfaction.

[0101] <Skin Cleansing Composition - Preparation of Facial Foam>

[0102] [Preparation Example 3]

[0103] Step (1): Add surfactant (raw materials 3 to 7) into a beaker and stir at 75°C using an Agi mixer to obtain a mixed solution.

[0104] Step (2): Add the polyol (raw material 2) and the mixture of step (1) to purified water (raw material 1) heated to 75°C, and stir them for 5 minutes at 3,500 rpm using a homogenizer (Premix, Japan) to obtain an emulsion.

[0105] Step (3): Cool the emulsion from step (2) to 50°C, and then slowly add the neutralizer (raw material 8) to it. Use a homogenizer (Premix, Japan) to stir them at 3,500 rpm for 5 minutes to adjust the viscosity of the emulsion.

[0106] Step (4): At 45°C, the abrasive particles (raw material 9) of Example 1 are added to the emulsion whose viscosity has been adjusted in step (3), and they are stirred to prepare facial foam.

[0107] [Preparation Example 4]

[0108] The facial cleansing foam was prepared using the same procedure as in Preparation Example 3, except that the exfoliating particles of Example 2 were used. The composition of the facial cleansing foam (in parts by weight) is shown in Table 3 below.

[0109] [Comparative Preparation Example 2]

[0110] The facial cleansing foam was prepared using the same procedure as in Preparation Example 3, except that step (4) of adding the abrasive particles from Example 1 under stirring was omitted, and the composition of the facial cleansing foam (unit: parts by weight) is shown in Table 3 below.

[0111] [Table 3]

[0112]

[0113] [Test Example 2] Cleaning Effectiveness Evaluation

[0114] The cleansing effects of the cleansing foams prepared in Preparation Examples 3 and 4, and Comparative Preparation Example 2, were evaluated. The results are shown in Table 4 below. Specifically, various makeup products were applied to the backs of the hands of 10 women in their 30s and 40s and 10 men in their 30s and 40s, respectively. Next, 2 g of each type of cleansing foam was applied to the back of the hand, moistened with water, rolled 10 times, and then washed off. The amount of makeup product remaining was evaluated, and the average value was calculated.

[0115] *Evaluation Criteria

[0116] Excellent: 0% to less than 5% of makeup remains after cleansing.

[0117] Excellent: Residual makeup product after cleansing is at least 5% - less than 25%.

[0118] Poor: At least 25% to 50% of makeup remains after cleansing.

[0119] Very poor: At least 50% to 100% of makeup remains after cleansing.

[0120] [Table 4]

[0121]

[0122] Referring to Table 4 above, the facial cleansing foams of Preparation Examples 3 and 4, which contain biodegradable exfoliating particles according to this disclosure, exhibit excellent cleaning effects (cleaning ability). In contrast, the facial cleansing foam of Comparative Preparation Example 2 (in which no biodegradable exfoliating particles were used) exhibits poor cleaning effects.

[0123] [Test Example 3] Evaluation of the effect of dead skin cell removal

[0124] The dead skin cell removal efficacy of the cleansing foams prepared in Preparation Examples 3 and 4, and Comparative Preparation Example 2, was evaluated. The results are shown in Table 5 below. Specifically, 2 g of each type of cleansing foam was applied to the back of the hands of 10 women in their 30s and 40s and 10 men in their 30s and 40s, respectively. The foam was moistened with water, rolled 10 times to generate foam, and then washed off. Next, the degree of dead skin cell removal from the back of the hands was evaluated using a callus tape (BOMTECH, stratum corneum type) device, and the average value was calculated.

[0125] *Evaluation Criteria

[0126] 1. Compared to the state before use, it removes 95% or more of dead skin cells.

[0127] 2. Compared to the state before use, it removes at least 60% to 80% of dead skin cells.

[0128] 3. Compared to the state before use, it removes at least 40% to 60% of dead skin cells.

[0129] 4. Compared to the state before use, less than 40% of dead skin cells were removed.

[0130] [Table 5]

[0131]

[0132] Referring to Table 5 above, the facial cleansing foams of Preparation Examples 3 and 4, which contain biodegradable exfoliating particles according to this disclosure, exhibit excellent dead skin cell removal effects. In contrast, the facial cleansing foam of Comparative Preparation Example 2 (in which no biodegradable exfoliating particles were used) shows very poor dead skin cell removal effects.

[0133] <Preparation of Skin Cleansing Composition - Shampoo>

[0134] [Preparation Example 5]

[0135] Step (1): Pour purified water (raw material 1), polyol (raw material 2), and thickener (raw material 3) into a beaker. Stir them using an Agi mixer while heating at 45°C to obtain a mixed solution.

[0136] Step (2): At 45°C, the surfactant (raw materials 4 to 6) and softener (raw material 7) are slowly added to the mixed solution of step (1) while stirring them at 500 rpm for 5 minutes using an Agi mixer to obtain dispersion 1.

[0137] Step (3): Keep the temperature at 45°C and slowly add the preservatives (raw materials 8 and 9) to dispersion 1 from step (2) while stirring them at 500 rpm for 5 minutes using an Agi mixer to obtain dispersion 2.

[0138] Step (4): While the temperature is maintained at 45°C, add the acidity regulator (raw material 10) to dispersion 2 from step (3) to adjust the pH. Then, slowly add the thickener (raw material 11) while stirring them at 700 rpm for 5 minutes using an Agi mixer to obtain dispersion 3.

[0139] Step (5): Keep the temperature at 45°C, add the abrasive particles (raw material 12) from Example 1 to the dispersion 3 from Step (4), and stir them at 700 rpm for 5 minutes using an Agi mixer to prepare the shampoo.

[0140] [Preparation Example 6]

[0141] The shampoo was prepared using the same procedure as in Preparation Example 5, except that the exfoliating particles from Example 2 were used. The composition of the shampoo (unit: parts by weight) is shown in Table 6 below.

[0142] [Comparative Preparation Example 3]

[0143] The shampoo was prepared using the same procedure as in Preparation Example 5, except that step (5) of adding the exfoliating particles of Example 1 under stirring was omitted, and the composition of the shampoo (unit: parts by weight) is shown in Table 6 below.

[0144] [Table 6]

[0145]

[0146] [Test Example 4] Evaluation of scalp cleansing effect

[0147] The scalp cleansing effects of the shampoos prepared in Preparation Examples 5 and 6, and Comparative Preparation Example 3, were evaluated. The results are shown in Tables 7 and 8 below. Specifically, 10 women in their 30s and 40s and 10 men in their 30s and 40s were each asked to apply 5 ml of each shampoo to their scalp each time. The user experience for each evaluation item was then rated, and the average score was calculated. Simultaneously, a usability evaluation as described above was conducted, along with a questionnaire regarding irritation.

[0148] *Evaluation Criteria

[0149] Excellent: 5

[0150] Excellent: 4

[0151] Normal: 3

[0152] Difference: 2

[0153] Very poor: 1

[0154] High: Highly irritating

[0155] Moderate: Moderately irritating

[0156] Low: Non-irritating

[0157] [Table 7]

[0158]

[0159] [Table 8]

[0160]

[0161] Referring to Table 7 above, the shampoos of Preparation Examples 5 and 6, which contain the biodegradable exfoliating particles according to this disclosure, exhibit excellent scalp massage and refreshing sensations, resulting in high usability satisfaction. In contrast, the shampoo of Comparative Preparation Example 3 (which did not use biodegradable exfoliating particles) has a poor scalp refreshing sensation, resulting in low usability satisfaction. Meanwhile, referring to Table 8 above, the shampoos of Preparation Examples 5 and 6, which contain biodegradable exfoliating particles, received an average "moderate" rating in the irritation evaluation, indicating no stinging or discomfort despite the use of biodegradable exfoliating particles. This demonstrates that the biodegradable exfoliating particles according to this disclosure have low skin irritation.

[0162] [Test Example 5] Formulation Stability Evaluation

[0163] The formulation stability of the skin cleansing compositions prepared in Preparation Examples 1 to 6 and Comparative Preparation Examples 1 to 3 was evaluated. The results are shown in Table 9 below. Specifically, the skin cleansing compositions were stored at each of the following temperature conditions: 4°C, 25°C, 45°C, and 50°C for 1 week, 2 weeks, and 1 month. The presence of precipitation and separation, discoloration, and odor changes was examined.

[0164] *Evaluation Criteria

[0165] ○: No precipitation, separation, discoloration, or odor change occurred.

[0166] ×: Sedimentation, separation, discoloration, or odor change may occur.

[0167] [Table 9]

[0168]

[0169] Referring to Table 9 above, the skin cleansing compositions of Preparation Examples 1 to 6 according to this disclosure exhibit excellent overall formulation stability even when they contain biodegradable exfoliating particles. In particular, when using exfoliating particles containing 10% by weight or less of the 4-HB repeating unit contained in the polyhydroxyalkanoate, the formulation stability is excellent even at temperatures of 45°C or higher.

Claims

1. Biodegradable abrasive particles comprising polyhydroxyalkanoate (PHA) containing 0.1 to 50% by weight of repeating units derived from 4-hydroxybutyrate (4-HB) based on the total weight of the polyhydroxyalkanoate (PHA), wherein the particle size (D) of the biodegradable abrasive particles is... 50 The range is 10 to 1,000 μm.

2. The biodegradable abrasive particles according to claim 1, wherein the polyhydroxyalkanoate (PHA) further comprises a repeating unit derived from at least one monomer selected from the group consisting of: 2-hydroxybutyrate (2-HB), 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 3-hydroxyheptanoate (3-Hhep), 3-hydroxyoctanoate (3-HO), 3-hydroxynonanoate (3-HN), 3-hydroxydecanoate (3-HD), 3-hydroxydodecanoate (3-HDd), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH).

3. The biodegradable abrasive particles according to claim 1, wherein the polyhydroxyalkanoate (PHA) further comprises repeating units derived from 3-hydroxybutyrate (3-HB).

4. The biodegradable abrasive particles according to claim 1, wherein the particle size (D) of the biodegradable abrasive particles is... 50 The range is 10 to 800 μm.

5. The biodegradable abrasive particles according to claim 1, wherein the content of the repeating units derived from 4-hydroxybutyrate (4-HB) is 1 to 10 by weight based on the total weight of polyhydroxyalkanoate (PHA).

6. A skin cleansing composition comprising the biodegradable exfoliating particles of claim 1; a surfactant; and a polyol.

7. The skin cleansing composition of claim 6, wherein the content of the biodegradable exfoliating particles is from 0.5 to 30% by weight based on the total weight of the skin cleansing composition.

8. The skin cleansing composition according to claim 6, wherein the content of the surfactant is 10 to 40% by weight based on the total weight of the skin cleansing composition, and the content of the polyol is 1 to 15% by weight based on the total weight of the skin cleansing composition.

9. The skin cleansing composition of claim 6, wherein the skin cleansing composition further comprises purified water, and The content of the biodegradable abrasive particles is 0.5 to 20 parts by weight relative to 100 parts by weight of the purified water.

10. The skin cleansing composition of claim 6, wherein the skin cleansing composition further comprises purified water, and The surfactant content is 20 to 60 parts by weight relative to 100 parts by weight of the purified water, and the polyol content is 0.5 to 25 parts by weight relative to 100 parts by weight of the purified water.

11. The skin cleansing composition of claim 6, wherein the surfactant comprises at least one selected from the group consisting of: cocamidopropyl betaine, potassium cocoyl glycinate, sodium oleate, stearic acid, myristic acid, lauric acid, glyceryl stearate, sodium lauryl ether sulfate, sodium cocoyl sulfate, sodium cocoyl ethanesulfonate, sodium lauroyl methyl ethanesulfonate, sodium lauroyl glutamate, sodium lauroyl aspartate, polysorbate 60, polysorbate 80, lauryl hydroxysulfonate betaine, sorbitol polyether-30 tetraoleate, sucrose laurate, polyglycerol-10 oleate, polyglycerol-10 dioleate, polyglycerol-2 sesquioctanoate, and lauryl ether-4.

12. The skin cleansing composition of claim 6, wherein the polyol comprises at least one selected from the group consisting of glycerin, 1,3-butanediol, dipropylene glycol, propylene glycol, polyethylene glycol, and 1,2-hexanediol.

13. The skin cleansing composition of claim 6, wherein the skin cleansing composition further comprises at least one selected from the group consisting of: moisturizers, emollients, thickeners, preservatives, neutralizers, acidity regulators, and fragrances.

14. The skin cleansing composition according to claim 6, used for cleansing the face, body or scalp.

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