Tumor electric field treatment system, electrode plate temperature detection method and electrode plate anomaly detection method

Abstract

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an electrode slice and an adapter provided with a first controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the first controller is connected with the adapter. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

Description

[0001] This invention is a divisional application of the invention patent application filed by the applicant on October 25, 2024, with application number 202411499593.0 and invention title "Tumor Electric Field Therapy System, Electrode Sheet, Tumor Therapy Device and Method". Technical Field

[0002] This application relates to tumor electric field therapy technology, and more particularly to a tumor electric field therapy system, an electrode temperature detection method, and an electrode abnormality detection method. Background Technology

[0003] Tumor electric field therapy is a treatment that uses low-intensity, medium-to-high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis in mitotic cells, thereby achieving the therapeutic effect on tumors.

[0004] Compared to traditional cancer treatments, tumor electric field (TEF) therapy has an innovative mechanism of action. Certain physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to TEF. TEF therapy disrupts the normal aggregation of tubulin by applying directional forces to intracellular polar particles (such as macromolecules and organelles). These processes can lead to physical damage to the cell membrane and apoptosis. During the telophase of mitosis, the morphology of the cleavage groove leads to an uneven distribution of the electric field around it. Under the influence of TEF, the electric field strength at the cleavage groove is significantly enhanced, causing charged substances in the cell to migrate towards the cleavage groove, interfering with or even destroying cell structure formation, ultimately leading to cell division failure and apoptosis.

[0005] In related technologies, tumor electric field therapy systems use an electric field application device to transmit alternating electrical signals for tumor electric field therapy to electrode pads. These pads then apply an alternating electric field to the patient's tumor site for tumor electric field therapy. When the tumor therapeutic electric field is applied to the patient's body, heat accumulates at the application site, causing a corresponding increase in temperature. Therefore, it is necessary to monitor the temperature at the application site. If the temperature becomes too high, the electric field intensity needs to be adjusted promptly to reduce the risk of burns to the patient's skin.

[0006] Tumor electric field therapy systems include at least one pair of electrode pads, each containing multiple electrode units. Even when the same alternating electrical signal is applied to each electrode unit, the heat generated on each unit will vary depending on its location. This means the temperature of each electrode unit across the entire electrode pad will not be completely uniform. Consequently, some electrode units may exceed a preset temperature while others remain at a normal temperature. To improve the effectiveness of tumor electric field therapy, individual control of overheating electrode units is necessary. However, for electrode pads in related technologies, individual control of electrode units requires a conductive trace for each electrode unit within the electrode pad's substrate. This increases the number of conductive traces within the substrate, making the electrode pad less flexible, and also thickens the cables electrically connected to the electrode pad, increasing its overall weight and hindering proper electrode application. Summary of the Invention

[0007] This application aims to at least partially address one of the technical problems in the related art. Therefore, the first objective of this application is to propose a tumor electric field therapy system that can control multiple electrode units in sections using fewer conductive traces, which not only improves the efficacy of tumor electric field therapy but also facilitates electrode application.

[0008] The second objective of this application is to provide a method for detecting the temperature of an electrode sheet.

[0009] The third objective of this application is to propose a method for detecting electrode sheet anomalies.

[0010] To achieve the above objectives, a first aspect of this application provides a tumor electric field therapy system, comprising: an electrode sheet including multiple electrode units and multiple temperature detection units, each electrode unit being capable of receiving an alternating electrical signal, each temperature detection unit being configured corresponding to one of the electrode units for detecting the temperature at each electrode unit, and the signal terminals of each temperature detection unit being short-circuited to the corresponding electrode unit, wherein the multiple temperature detection units are configured in a circuit as multiple row groups and multiple column groups, the ground terminals of each temperature detection unit located in the same row group are short-circuited to the same grounding line, the ground terminals of each temperature detection unit located in different row groups are connected in parallel through different grounding lines, and the ground terminals of each temperature detection unit located in the same column group are short-circuited to the same grounding line. The signal terminals of the unit are shorted to the same dual-purpose signal line, and the signal terminals of the temperature detection units located in different columns are connected in parallel through different dual-purpose signal lines; and an electric field generator that provides an alternating electrical signal and is equipped with a second controller, the second controller being configured to switch each dual-purpose signal line to a temperature sampling point or an alternating power supply line so that (1) when each dual-purpose signal line is connected to the corresponding temperature sampling point, each grounding line is sequentially turned on so that the temperature detection signal detected by each temperature detection unit is sampled based on the corresponding temperature sampling point; (2) when each dual-purpose signal line is connected to the alternating power supply line, the alternating electrical signal is transmitted to each electrode unit through each dual-purpose signal line.

[0011] According to the tumor electric field therapy system of this application, multiple temperature detection units of the electrode pads are divided into multiple row groups and multiple column groups. The grounding terminals of the temperature detection units corresponding to each electrode unit in each row group are connected to the same grounding line. The signal terminals of the temperature detection units corresponding to each electrode unit in each column group are short-circuited with their respective electrode units and then connected to the same dual-purpose signal line. Simultaneously, a second controller controls the dual-purpose signal line to connect to either a temperature sampling point or an alternating power supply line. When the dual-purpose signal line is connected to a temperature sampling point, each grounding line is sequentially activated so that the temperature detection signals detected by each temperature detection unit are sampled based on the temperature sampling point. When the dual-purpose signal line is connected to an alternating power supply line, an alternating electrical signal is transmitted to each electrode unit via the dual-purpose signal line. Thus, temperature sampling and alternating electrical signal application can be achieved through the dual-purpose signal line. This not only avoids adding new AC signal lines but also eliminates the need for existing AC signal lines. Therefore, multiple electrode units can be controlled in sections using fewer conductive traces, which not only improves the effect of tumor electric field therapy but also facilitates electrode pad application.

[0012] To achieve the above objectives, a second aspect of this application provides an electrode temperature detection method applied to the aforementioned tumor electric field therapy system, comprising: connecting each of the dual-purpose signal lines to the temperature sampling point; and sequentially and individually energizing each of the grounding lines so that the temperature detection signals detected by each of the temperature detection units are sampled based on each corresponding temperature sampling point.

[0013] To achieve the above objectives, a third aspect of this application provides a method for detecting abnormalities in an electrode sheet, applied to the aforementioned tumor electric field therapy system. The method includes: connecting each of the dual-purpose signal lines to the temperature sampling point; sequentially and individually energizing each of the grounding lines so that the temperature detection signals detected by each of the temperature detection units are sampled based on the corresponding temperature sampling points; and determining whether the electrode sheet is abnormal based on each temperature detection signal.

[0014] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application and to implement it in accordance with the contents of the specification, and to make the above and other objects, features and advantages of this application more obvious and understandable, specific embodiments of this application are given below. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of a tumor electric field therapy system according to an embodiment of this application;

[0016] Figure 2 for Figure 1 The diagram shows the structure of the electrode pads in the tumor electric field therapy system.

[0017] Figure 3 for Figure 1 The diagram shows the circuit connection between an electrode plate and an adapter in a tumor electric field therapy system.

[0018] Figure 4 and Figure 3 Similarly, it is Figure 3 The diagram shows the connection between one electrode plate and another circuit of the adapter.

[0019] Figure 5 for Figure 1 The diagram shows the circuit connection between an electrode plate, an adapter, and an electric field generator in the tumor electric field therapy system.

[0020] Figure 6 for Figure 1 A schematic block diagram of the internal structure of the adapter of the tumor electric field therapy system is shown.

[0021] Figure 7 for Figure 1 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy system is shown.

[0022] Figure 8 This is a schematic flowchart of an electrode temperature detection method according to an embodiment of this application;

[0023] Figure 9 This is a flowchart illustrating an electrode sheet anomaly detection method according to an embodiment of this application;

[0024] Figure 10 This is a schematic flowchart of a control method for a tumor electric field therapy system according to an embodiment of this application;

[0025] Figure 11 This is a flowchart illustrating an embodiment of the electrode type identification method of this application;

[0026] Figure 12 This is a schematic flowchart of a signal control method for tumor electric field therapy according to an embodiment of this application;

[0027] Figure 13 This is a schematic flowchart of an electrode temperature detection method according to another embodiment of this application;

[0028] Figure 14 This is a flowchart illustrating a method for applying alternating electrical signals for tumor electric field therapy according to another embodiment of this application.

[0029] Figure 15 This is a schematic flowchart of an embodiment of the alternating current signal application method based on a temperature detection signal according to this application;

[0030] Figure 16 This is a flowchart illustrating another embodiment of the alternating electrical signal application method based on a temperature detection signal.

[0031] Figure 17 This is a schematic diagram of a tumor electric field therapy system according to another embodiment of this application;

[0032] Figure 18 This is a schematic diagram of the circuit connection between an electrode, an adapter, and an electric field generator in a tumor electric field therapy system according to another embodiment of this application.

[0033] Figure 19 for Figure 18 A schematic block diagram of the internal structure of the adapter of the tumor electric field therapy system is shown.

[0034] Figure 20 for Figure 18 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy system is shown.

[0035] Figure 21 This is a flowchart illustrating a control method for a tumor electric field therapy system according to another embodiment of this application.

[0036] Figure 22 This is a schematic flowchart of a signal control method for tumor electric field therapy according to another embodiment of this application;

[0037] Explanation of reference numerals in the attached figures:

[0038] Tumor electric field therapy system 100 or 100', electrode pads 13 or 13', first cable 15 or 15', adapter 20 or 20', second cable 25 or 25', electric field generator 30 or 30', substrate 31 or 31', electrode unit 33 or 33', temperature detection unit 35 or 35', grounding terminal 35-1 or 35-1', signal terminal 35-2 or 35-2', temperature sensor 34 or 34', grounding terminal 34-1 or 34-1', signal terminal 34-2 or 34-2', electrode unit 33 or 33', diode 36 or 36'. Anode 36-1 or 36-1', Cathode 36-2 or 36-2', Second power module 32 or 32', Second controller 37 or 37', Second communication unit 38 or 38', AC signal generator 39 or 39', Power supply switch 40 or 40', First controller 51 or 51', ADC unit 52 or 52', Voltage divider resistor 53 or 53', Control switch 54 or 54', First control switch 54-1 or 54-1', Second control switch 54-2 or 54-2', Third control switch 54-3 or 54-3', Fourth control switch 54- 4 or 54-4', bidirectional switch 55 or 55', first bidirectional switch 55-1 or 55-1', second bidirectional switch 55-2 or 55-2', third bidirectional switch 55-3 or 55-3', fourth bidirectional switch 55-4 or 55-4', fifth bidirectional switch 55-5 or 55-5', first communication unit 56 or 56', alternating power line 57 or 57', first power module 58 or 58', grounding wire 18 or 18', first grounding wire 18-1 or 18-1', second grounding wire 18-2 or 18-2' The third grounding wire is 18-3 or 18-3', the fourth grounding wire is 18-4 or 18-4', the dual-purpose signal wire is 19 or 19', the first dual-purpose signal wire is 19-1 or 19-1', the second dual-purpose signal wire is 19-2 or 19-2', the third dual-purpose signal wire is 19-3 or 19-3', the fourth dual-purpose signal wire is 19-4 or 19-4', the fifth dual-purpose signal wire is 19-5 or 19-5', the first connector is 60 or 60', the first plug is 61, the first socket is 62, the second connector is 70 or 70', the second plug is 71 or 71', and the second socket is 72 or 72'. Detailed Implementation

[0039] The embodiments of the technical solution of this application will now be described in detail with reference to the accompanying drawings. These embodiments are only used to more clearly illustrate the technical solution of this application and are therefore merely examples, and should not be used to limit the scope of protection of this application.

[0040] Example 1:

[0041] Figure 1 The diagram shown is a schematic representation of a tumor electric field therapy system 100 according to an embodiment of this application. Figure 1 As shown, the tumor electric field therapy system 100 includes: at least one pair of electrode pads 13, an adapter 20 connected to the at least one pair of electrode pads 13, and an electric field generator 30 connected to the adapter 20. The at least one pair of electrode pads 13 can be disposed in pairs on the patient's body surface, such as... Figure 1 The device comprises four electrode pads 13, with each pair of electrode pads 13 positioned on the patient's body surface. An electric field generator 30 supplies power to at least one pair of electrode pads 13, causing them to generate an alternating electric field for tumor treatment. An adapter 20 is electrically connected between the at least one pair of electrode pads 13 and the electric field generator 30, for transmitting the alternating electrical signal generated by the electric field generator 30 to the at least one pair of electrode pads 13. In other words, the electric field generator 30 generates an alternating electrical signal, which is transmitted through the adapter 20 to each electrode pad 13, thereby generating an alternating electric field for tumor treatment between the same pair of electrode pads 13, thus applying the alternating electric field to the patient's tumor site for tumor therapy.

[0042] like Figure 1 As shown, in this embodiment, there are four electrode pads 13, each electrode pad 13 including the same number of electrode units 33, each electrode unit 33 being electrically connected to the adapter 20, and each electrode pad 13 having 20 electrode units 33. In other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode pads 13; in other embodiments, each pair of electrode pads 13 has the same number of electrode units 33, and different pairs of electrode pads 13 may have different numbers of electrode units 33; in other embodiments, the number of electrode units 33 on each electrode pad 13 may be 9, 13, etc.

[0043] Figure 3 and Figure 4 for Figure 1 The diagram shows the circuit connection between the electrode 13 and the adapter 20 in two operating states of the tumor electric field therapy system 100. It is worth noting that: Figure 3 and Figure 4 The arrangement of electrode units 33 shown is to more clearly illustrate the electrical connection between an electrode piece 13 and the adapter 20. Figure 3 and Figure 4 The arrangement of electrode units 33 shown does not represent their spatial arrangement. (Combined with...) Figure 1 , Figure 3 as well as Figure 4The electrode sheet 13 includes: a substrate 31, a plurality of electrode units 33 electrically connected to the substrate 31 at intervals, a plurality of temperature detection units 35, and a first cable 15 electrically connected to the substrate 31. The substrate 31 may be a flexible circuit board. The substrate 31 is embedded with multiple conductive traces, including multiple ground lines 18 and multiple dual-purpose signal lines 19. The first cable 15 has multi-core wires (not shown), each of which is electrically connected to the multiple ground lines 18 and the multiple dual-purpose signal lines 19 of the substrate 31 in a one-to-one correspondence. In this embodiment, the total number of ground lines 18 and dual-purpose signal lines 19 embedded in the substrate 31 does not exceed 10, therefore the number of wires in the first cable 15 does not exceed 10.

[0044] Multiple electrode units 33 are configured into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13 has 20 electrode units 33, which are arranged in a sequence from 1 to 20 in the circuit connection, divided into four row groups and five column groups, that is, the 20 electrode units 33 are arranged in four rows and five columns in the circuit connection. Each electrode unit 33 corresponds to a temperature detection unit 35, and each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1. Both the electrode units 33 and the temperature detection units 35 are soldered to the substrate 31, and the signal terminal 35-2 of the electrode unit 33 is shorted to the corresponding temperature detection unit 35. Since the multiple temperature detection units 35 are arranged in a one-to-one correspondence with the multiple electrode units 33, the multiple temperature detection units 35 are also arranged in four rows and five columns in the circuit connection. It should be noted that the arrangement shown here is to more clearly illustrate the electrical connection between electrode 13 and adapter 20, and does not represent the spatial arrangement of electrode unit 33. Its spatial structure may be as follows: Figure 2The structure shown is roughly array-like, but it can also be other structures, such as petal-shaped or scattering-shaped, and can be regular or irregular. Electrode unit 33 is configured to apply an alternating electric field to the patient's tumor site. Temperature detection unit 35 is configured to detect the temperature of the patient's body surface that is in contact with electrode pad 13, i.e., the temperature at the corresponding electrode unit 33, and output a temperature detection signal to adapter 20. In this embodiment, the multi-purpose signal lines 19 of substrate 31 are respectively arranged in a one-to-one correspondence with multiple columns of electrode units 33, and are configured to transmit the alternating electrical signal generated by electric field generator 30 to each electrode unit 33 in the corresponding column. That is, electrode units 33 located in the same column are all short-circuited through the same multi-purpose signal line 19 of substrate 31, and electrode units 33 located in different columns are connected in parallel through different multi-purpose signal lines 19 of substrate 31. The multi-purpose signal lines 19 of substrate 31 are electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via adapter 20. Furthermore, the dual-purpose signal line 19 of the substrate 31 receives the alternating electrical signal generated by the electric field generator 30 through the first cable 15 and the adapter 20.

[0045] Each electrode pad 13 has three operating modes. In the first mode, an AC signal is applied through the electrode unit 33. In the second mode, the temperature of the patient's body surface to which the corresponding electrode unit 33 is applied is detected or acquired through the temperature detection unit 35. In the third mode, the application of the AC signal and temperature detection and acquisition cease. The first, second, and third modes do not overlap in time. That is, the time period during which the electrode unit 33 applies the AC signal and the time period during which the temperature detection unit 35 detects the temperature are staggered and do not overlap. The electrode pad 13 can cycle between applying the AC signal through its electrode unit 33 and detecting the temperature through its temperature detection unit 35, i.e., the electrode pad 13 cycles between the first and second modes. The electrode pad 13 can also cycle between the first, second, and third modes, i.e., the electrode pad 13 cycles between applying the AC signal through the electrode unit 33, acquiring or detecting the temperature through the temperature detection unit 35, ceasing the application of the AC signal, and acquiring the temperature.

[0046] Each of the multiple grounding lines 18 is correspondingly configured to one of the multiple rows of electrode units 33, and each of the multiple grounding lines 18 is used to sequentially short-circuit and ground each temperature detection unit 35 in each row. That is, the grounding terminals 35-1 of multiple temperature detection units 35 located in the same row are all short-circuited through the same grounding line 18 of the substrate 31, and the grounding terminals 35-1 of temperature detection units 35 located in different rows are connected in parallel through different grounding lines 18 of the substrate 31. During the temperature detection period, only one of the multiple grounding lines 18 is conducting at any given time, while the other three are disconnected.

[0047] Each of the multiplexed dual-purpose signal lines 19 is further configured to short-connect the signal terminal 35-2 of at most one temperature detection unit 35 in each row group to an external device for receiving detection signals. The signal terminals 35-2 of the temperature detection units 35 connected to each of the multiplexed dual-purpose signal lines 19 are different to avoid subsequent output of duplicate signals by the dual-purpose signal lines 19. That is, when the number of electrode units 33 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 35-2 of a different temperature detection unit 35 in that row group; when the number of electrode units 33 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal terminal 35-2 of a temperature detection unit 35, and the remaining dual-purpose signal lines 19 are electrically connected to the signal terminal 35-2 of a different temperature detection unit 35 in that row group. In this embodiment, the external device for receiving detection signals is an adapter 20. The signal terminals 35-2 of multiple temperature detection units 35 located in different columns are connected in parallel through different dual-purpose signal lines 19 of the substrate 31. The signal terminals 35-2 of multiple temperature detection units 35 located in the same column are all shorted to the same dual-purpose signal line 19 of the substrate 31.

[0048] In this embodiment, with a temperature detection unit 35 configured in each electrode unit 33 for temperature detection, the above-described circuit design reduces the number of wires in the first cable 15, avoiding increased cable thickness and stiffness that would complicate cable fixation; simultaneously, it prevents an increase in the number of wires in the first cable 15 from affecting the adhesion between the electrode sheet 13 and the corresponding body surface of the patient's tumor site. The substrate 31 contains a total of 9 lines: grounding wire 18 and dual-purpose signal lines 19. Specifically, in this embodiment, the substrate 31 contains 4 grounding wires and 5 dual-purpose signal lines 19. The number of grounding wires 18 is related to the number of rows M of the electrode unit 33, and is greater than or equal to the number of rows M, where M is a positive integer. The number of dual-purpose signal lines 19 is related to the number of columns N of the electrode unit 33, and is greater than or equal to the number of columns N, where N is a positive integer. The number of lines L embedded in the substrate 31 of the electrode sheet 13 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal lines 19. In this embodiment, the number of grounding wires 18 is equal to the number of rows M of electrode unit 33; the number of dual-purpose signal lines 19 is equal to the number of columns N of electrode unit 33.

[0049] Multiple electrode units 33 are arranged in a roughly two-dimensional array on the substrate 31 at intervals. For example... Figure 2As shown, the electrode sheet 13 in this embodiment includes 20 electrode units 33 and 20 temperature detection units 35 corresponding to the electrode units 33. The 20 electrode units 33 are arranged in a four-row, six-column array. The first and fourth rows each have four electrode units 33, and the second and third rows each have six electrode units 33. The four electrode units 33 in each of the first and fourth rows are located in each of the second to fifth columns, and the six electrode units 33 in each of the second and third rows are located in each of the first to sixth columns. The four electrode units 33 in the first row are divided into region 1; the electrode units 33 in the first column of the second row, the first column of the third row, and the second and third columns of the fourth row are divided into region 2; the electrode units 33 in the sixth column of the second row, the sixth column of the third row, and the fourth and fifth columns of the fourth row are divided into region 3; the electrode units 33 in the second and third columns of the second row and the second and third columns of the third row are divided into region 4; and the electrode units 33 in the fourth and fifth columns of the second row and the fourth and fifth columns of the third row are divided into region 5. Each region (1-5) corresponds to a column group. In some other embodiments, the 20 electrode units 33 may also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 13 may also have other numbers of electrode units 33. In summary, the implementation of this application is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13.

[0050] Each electrode unit 33 can be subjected to an alternating electrical signal, thereby enabling the paired electrode sheets 13 to apply an alternating electric field to the tumor site of the patient. Optionally, the electrode unit 33 is a dielectric element, such as a ceramic sheet, or a polymer dielectric layer made of polymer material. Each temperature detection unit 35 is provided corresponding to one electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 35 can be located at any position of the corresponding electrode unit 33. In this embodiment, each electrode unit 33 is provided with a through hole 331, which is suitable for installing the temperature detection unit 35. For example, each electrode unit 33 has a through hole 331 in the middle, and each electrode unit 33 has a corresponding temperature detection unit 35 housed in the through hole 331. Each temperature detection unit 35 includes a temperature sensor 34 and a diode 36. The temperature sensor 34 has a signal terminal 34-2 and a ground terminal 34-1. The diode 36 has an anode 36-1 and a cathode 36-2. The anode 36-1 of the diode 36 is connected to the ground terminal 34-1 of the temperature sensor 34. The cathode 36-2 of the diode 36 serves as the ground terminal 35-1 of the temperature detection unit 35, and the signal terminal 34-2 of the temperature sensor 34 serves as the signal terminal 35-2 of the temperature detection unit 35. The temperature sensor 34 can be a thermistor or other temperature sensors. Each temperature sensor 34 corresponds to a diode 36, which is connected in series with the corresponding temperature sensor 34. This diode prevents reverse current flow to prevent detection signals from other electrode units 33 from affecting the temperature sensor 34.

[0051] like Figure 3 or Figure 4As shown, the electrode plate 13 in this embodiment includes four grounding wires 18, each grounding wire 18 being used to ground the grounding terminals 35-1 of the temperature detection units 35 in the same row group. The four grounding wires 18 of the electrode plate 13 are the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4. In the four rows of the electrode plate 13, the first row group consists of electrode units 33-1 to 33-5, the second row group consists of electrode units 33-6 to 33-10, the third row group consists of electrode units 33-11 to 33-15, and the fourth row group consists of electrode units 33-16 to 33-20. Specifically, the first grounding wire 18-1 is used to ground electrode units 33-1 to 33-5 in the first row group; the second grounding wire 18-2 is used to ground electrode units 33-6 to 33-10 in the second row group; the third grounding wire 18-3 is used to ground electrode units 33-11 to 33-15 in the third row group; and the fourth grounding wire 18-4 is used to ground electrode units 33-16 to 33-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or opened. This can be achieved by connecting each grounding wire 18 in series with a control switch 54. That is, the grounding terminals 35-1 of the temperature detection units 35 corresponding to each electrode unit 33 in each row group are connected to the grounding pin through a single control switch 54, which will be described in detail below. The aforementioned "grounding the electrode unit 33" can refer to grounding the grounding terminal 34-1 of the temperature sensor 34 corresponding to each electrode unit 33, or it can refer to connecting the diode 36 in series with the corresponding temperature sensor 34 and grounding them together. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 35-1 of the temperature detection units 35 corresponding to all electrode units 33 in each row group.

[0052] like Figure 3 or Figure 4As shown, the electrode sheet 13 in this embodiment also includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to the signal terminal 35-2 of all electrode units 33 in each row group and the temperature detection unit 35 corresponding to each electrode unit 33, and the other end is connected to the adapter 20 for receiving temperature detection signals and transmitting alternating electrical signals. That is, for each row group, each dual-purpose signal line 19 can be selectively connected to one of the electrode units 33 or not connected to any of the electrode units 33 in that row group to avoid the dual-purpose signal line 19 outputting repeated signals in the future. Specifically, the five dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the signal terminals 35-2 of four electrode units 33 (electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16) and their respective temperature detection units 35; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the signal terminals 35-2 of four electrode units 33 (electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17) and their respective temperature detection units 35; one end of the third dual-purpose signal line 19-3 is simultaneously connected to electrode units 33-3, 33-8, and 33-9. -13, the signal terminals 35-2 of the four electrode units 33 and their corresponding temperature detection units 35 of electrode units 33-18 are connected simultaneously at one end of the fourth dual-purpose signal line 19-4; the signal terminals 35-2 of the four electrode units 33 (33-4, 33-9, 33-14, and 33-19) and their corresponding temperature detection units 35 of electrode units 33-4, 33-9, 33-14, and 33-19 are connected simultaneously at one end of the fifth dual-purpose signal line 19-5; the signal terminals 35-2 of the four electrode units 33 (33-5, 33-10, 33-15, and 33-20) and their corresponding temperature detection units 35 of electrode units 33-5, 33-10, 33-15, and 33-20 are connected simultaneously of the fifth dual-purpose signal line 19-5. In short, each dual-purpose signal line 19 short-circuits the signal terminals 35-2 of each electrode unit 33 and its corresponding temperature detection unit 35 in parallel within the same column group for connection to external devices. It should be noted that these dual-purpose signal lines 19 can selectively transmit alternating electrical signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switching switch 55 and coordinating with the closing or opening of the grounding wire 18.In other words, after the signal terminals 35-2 of each temperature detection unit 35 in each column group are shorted to the corresponding electrode unit 33, they are connected to a switching unit (unlabeled) through a dual-purpose signal line 19. The switching unit (unlabeled) includes multiple bidirectional switching switches 55, which are configured to switch the dual-purpose signal line 19 to either the temperature sampling point (unlabeled) or the alternating power line 57. When the dual-purpose signal line 19 is connected to the temperature sampling point (unlabeled), the switching state of the control switch 54 is configured so that the temperature detection signal detected by the corresponding temperature detection unit 35 in each row group is sampled based on the temperature sampling point (unlabeled). When the dual-purpose signal line 19 is connected to the alternating power line 57, at least one column group's electrode unit 33 is subjected to an alternating electrical signal based on the alternating power line 57. This will be described in detail below.

[0053] The multi-path grounding line 18 and the multi-path dual-purpose signal line 19 are both conductive traces embedded in the substrate 31. The substrate 31 is electrically connected to the first cable 15. The multi-path grounding line 18 and the multi-path dual-purpose signal line 19 embedded in the substrate 31 are electrically connected to the corresponding wires (not shown) in the first cable 15.

[0054] The tumor electric field therapy system 100 of this embodiment includes at least one pair of electrode pads 13 as described above, an adapter 20 electrically connected to the electrode pads 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode pads 13 and the electric field generator 30. The electric field generator 30 provides alternating electrical signals to multiple electrode units 33 of the electrode pads 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode pads 13, or is used to receive temperature detection signals output by temperature detection units 35 corresponding to multiple electrode units 33. The adapter 20 transmits the alternating electrical signals generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode pads 13, and is also configured to receive temperature detection signals output by the multiple dual-purpose signal lines 19 of the electrode pads 13.

[0055] refer to Figure 3 and Figure 4As shown, the adapter 20 includes: a first controller 51, multiple ADC units 52 connected to the first controller 51, multiple voltage-reducing resistors 53 and multiple control switches 54 corresponding to each of the multiple ADC units 52, multiple bidirectional switching switches 55 corresponding to each of the multiple ADC units 52, a first communication unit 56, an alternating power line 57 corresponding to each of the bidirectional switching switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51, and the multiple ADC units 52. The first power module 58 provides DC power VCC to each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled), which are electrically connected to multiple grounding lines 18 and multiple dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plates 13 through the first cables 15 of the corresponding electrode plates 13. The multiple circuit lines (unlabeled) include multiple alternating power supply lines 57 that transmit alternating electrical signals to the corresponding electrode plates 13 and are electrically connected to the multiplexed dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plate 13; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiplexed dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plates 13 and are used to power each temperature detection unit 35 of the electrode plate 13 or transmit the temperature detection signal of the electrode plate 13; and multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiple grounding lines 18 in the substrate 31 of the corresponding electrode plates 13. The number L of circuit lines that the adapter 20 is electrically connected to one electrode plate 13 is equal to the sum of the number of rows and columns of the electrode units 33 of the electrode plate 13; the number H of circuit lines that the adapter 20 is electrically connected to X electrode plates 13 is equal to X times the number of circuit lines that it is electrically connected to a single electrode plate 13, that is, H=XL=X×(M+N). The number of groups of control switches 54 and bidirectional switching switches 55 are related to the number of electrode plates 13. The number of groups of control switches 54 and bidirectional switching switches 55 is the same and not less than the number of electrode plates 13. Optionally, the number of groups of control switches 54 and bidirectional switching switches 55 is the same as the number of electrode plates 13. The following detailed description only takes the electrical connection between an electrode plate 13 with 20 electrode units 33 and the adapter 20 as an example.

[0056] Each group of control switches 54 has multiple control switches 54, which are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding wires 18 of a corresponding electrode plate 13, and are configured to control the on or off of the multiple grounding wires 18. The circuit lines (unlabeled) that are each electrically connected to the multiple grounding wires 18 of the electrode plate 13 are grounded at the end closest to the control switch 54. The number of control switches 54 in each group of control switches 54 is related to the number of grounding wires 18 on the substrate 31 of the corresponding electrode plate 13; in this embodiment, the two are equal. Figure 3 or Figure 4 As shown, in this embodiment, the multiple control switches 54 are respectively a first control switch 54-1, a second control switch 54-2, a third control switch 54-3, and a fourth control switch 54-4. The multiple control switches 54 in the same group each control the opening or closing of the corresponding grounding wire 18 of the same electrode plate 13. The first control switch 54-1 is used to control the opening or closing of the first grounding wire 18-1 of the corresponding electrode plate 13, and can then cooperate with the corresponding group of bidirectional switching switches 55 to control the energization and de-energization of the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 in the first row group 33 of the electrode plate 13; the second control switch 54-2 is used to control the opening or closing of the second grounding wire 18-2 of the electrode plate 13, and can then cooperate with the corresponding group of bidirectional switching switches 55 to control the energization and de-energization of the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 in the second row group 33 of the electrode plate 13; the... The third control switch 54-3 is used to control the opening or closing of the third grounding wire 18-3 of the electrode plate 13, and can cooperate with the corresponding set of bidirectional switching switches 55 to control the energization and de-energization of the temperature detection units 35 corresponding to the five electrode units 33 (33-11 to 33-15) in the third row group 33 of the electrode plate 13; the fourth control switch 54-4 is used to control the opening or closing of the fourth grounding wire 18-4 of the electrode plate 13, and can cooperate with the corresponding set of bidirectional switching switches 55 to control the energization and de-energization of the temperature detection units 35 corresponding to the five electrode units 33 (33-16 to 33-20) in the fourth row group 33 of the electrode plate 13. The control switches 54 can be mechanical switches, such as relays. The control switches 54 can also be electronic switches, and each control switch 54 can be opened and closed by an additional first controller 51.

[0057] In this embodiment, all sets of control switches 54 are electronic switches. The first controller 51 is communicatively connected to the multiple sets of control switches 54, and is used to sequentially and cyclically control the opening and closing states of multiple control switches 54 in each set, thereby sequentially and individually activating each of the multiple grounding wires 18 of the corresponding electrode pad 13 and coordinating with the switching of the corresponding bidirectional switching switch 55 to collect the patient's body surface temperature detected by all temperature detection units 35 on the electrode pad 13. The number of each set of control switches 54 is not less than the number of grounding wires 18 on the substrate 31 of the corresponding electrode pad 13. In this embodiment, the number of each set of control switches 54 is the same as the number of grounding wires 18 on the corresponding electrode pad 13.

[0058] Each group of bidirectional switching switches 55 is provided with multiple bidirectional switching switches 55. The multiple bidirectional switching switches 55 in each group are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) that correspond one-to-one with the multi-purpose signal lines 19 of the corresponding electrode plate 13. The number of bidirectional switching switches 55 in each group of bidirectional switching switches 55 is related to the number of dual-purpose signal lines 19 on the substrate 31 of the corresponding electrode plate 13, which is greater than or equal to the number of dual-purpose signal lines 19 on the substrate 31 of the corresponding electrode plate 13. In this embodiment, the two are equal. Each bidirectional switch 55 has a signal acquisition terminal 1 labeled 1 and a signal input terminal 2 labeled 2. The signal acquisition terminals 1 of multiple bidirectional switches 55 in the same group are electrically connected to the corresponding detection channels of multiple detection channels of the corresponding group of ADC units 52 through temperature sampling points (unlabeled). The signal input terminal 2 of each bidirectional switch 55 in the same group is electrically connected to the same AC power line 57 and is configured to control the multi-purpose signal line 19 to connect to the corresponding AC power line 57 to transmit AC electrical signals or to connect to the corresponding detection channel of the corresponding group of ADC units 52 to receive the temperature detection signal output by the temperature detection unit 35.

[0059] like Figure 3 or Figure 4As shown, taking the electrical connection of one electrode plate 13 with the adapter 20 as an example, in this embodiment with 20 electrode units 33, the multiple bidirectional switching switches 55 are respectively the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5. The multiple bidirectional switching switches 55 in the same group each control the switching of a corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 of the same electrode plate 13 between transmitting alternating electrical signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 55-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode pad 13 between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33 in the first column of electrode units 33-1, 33-6, 33-11, and 33-16 and the conduction of the signal terminals 35-2 of the corresponding temperature detection units 35 in the first column of electrode units 33-1, 33-6, 33-11, and 33-16, and the conduction of the corresponding temperature detection units 35 in the first column of electrode units 33-1, 33-6, 33-11, and 33-16. This also works in conjunction with corresponding control switches 54-1, 54-2, 54-3, and 54-4 to enable the first column of electrode units 33-1, 33-6, 33-11, and 33-16 to transmit alternating electrical signals to the patient or to output temperature detection data collected by the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. Signal; The second bidirectional switching switch 55-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode 13 between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the conduction of each electrode unit 33 of the electrode units 33-2, 33-7, 33-12, and 33-17 in the second column of the electrode 13 and the conduction of the signal terminals 35-2 of the corresponding temperature detection units 35 in the second column of the electrode units 33-2, 33-7, 33-12, and 33-17, and cooperating with the corresponding control switches 54-1, 54-2, 54-3, and 54-4, so that the second column of electrode units 33-2, 33-7, 33-12, and 33-17 transmits alternating electrical signals to the patient or outputs temperature detection signals collected by the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52;The third bidirectional switching switch 55-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode 13 between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33 in the third column of the electrode 13 (electrode units 33-3, 33-8, 33-13, and 33-18) and the conduction of the signal terminals 35-2 of the corresponding temperature detection units in the third column of the electrode 13. It also cooperates with the corresponding control switches 54-1, 54-2, 54-3, and 54-4 to enable the third column of electrode units 33-3, 33-8, 33-13, and 33-18 to transmit alternating electrical signals to the patient or output temperature detection signals collected by the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. The fourth bidirectional switching switch 55-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode 13 between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33 in the fourth column of the electrode 13 (electrode units 33-4, 33-9, 33-14, and 33-19) and the conduction of the signal terminals 35-2 of the corresponding temperature detection units 35 in the fourth column of the electrode 13. The switch also cooperates with the corresponding control switches 54-1, 54-2, 54-3, and 54-4 to enable the fourth column of electrode units 33-4, 33-9, 33-14, and 33-19 to transmit alternating electrical signals to the patient or to output temperature detection signals collected by the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52.The fifth bidirectional switching switch 55-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode pad 13 between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33 in the fifth column group of electrode units 33-5, 33-10, 33-15, and 33-20 and the conduction of the signal terminals 35-2 of the corresponding temperature detection units 35 in the fifth column group of electrode units 33-5, 33-10, 33-15, and 33-20, and cooperates with the corresponding control switches 54-1, 54-2, 54-3, and 54-4 to enable the fifth column of electrode units 33-5, 33-10, 33-15, and 33-20 to transmit alternating electrical signals to the patient or output the temperature detection signals collected by the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. When the signal input terminal 2 of each set of bidirectional switching switches 55 is turned on and the signal acquisition terminal 1 is turned off, alternating electrical signals can be transmitted to each electrode unit 33 of the corresponding electrode plate 13. When the signal acquisition terminal 1 of each set of bidirectional switching switches 55 is turned on and the signal input terminal 2 is turned off, it can cooperate with each control switch 54 in the corresponding set of control switches 54 to transmit the temperature detection signals collected by each temperature detection unit 35 on the electrode plate 13 in a time-division manner. The aforementioned bidirectional switching switches 55 can be mechanical switches, such as relays. The bidirectional switching switches 55 can also be electronic switches, and each bidirectional switching switch 55 can be switched by an additional first controller 51.

[0060] In this embodiment, all of the multiple bidirectional switching switches 55 are electronic switches. The first controller 51 is communicatively connected to the multiple bidirectional switching switches 55 and is used to control the switching of multiple bidirectional switching switches 55 in each group between their respective signal acquisition terminal 1 and signal input terminal 2, and to cooperate with the closing or opening of the corresponding control switch 54, so as to continuously monitor the temperature of the patient's body surface detected by all temperature detection units 35 on the electrode pad 13 or transmit alternating electrical signals to the patient.

[0061] In this embodiment, each ADC unit 52 is electrically connected one-to-one to the signal acquisition terminals 1 of multiple bidirectional switching switches 55 in the corresponding group via multiple circuit lines (unlabeled) within the adapter 20, and is configured to receive temperature detection signals transmitted from the multi-purpose signal lines 19 of the corresponding electrode 13, and convert the temperature detection signals from analog signals to digital signals. Each ADC unit 52 includes multiple detection channels A, B, C, D, and E, each detection channel A, B, C, D, and E is used to connect to one corresponding dual-purpose signal line 19 in the multi-purpose signal lines 19 via the corresponding bidirectional switching switch 55. Figure 3 or Figure 4 As shown, each ADC unit 52 contains five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 via the signal acquisition terminal 1 of the first bidirectional switch 55-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 via the signal acquisition terminal 1 of the second bidirectional switch 55-2; the third detection channel C is connected to the third dual-purpose signal line 19-3 via the signal acquisition terminal 1 of the third bidirectional switch 55-3; the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 via the signal acquisition terminal 1 of the fourth bidirectional switch 55-4; and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 via the signal acquisition terminal 1 of the fifth bidirectional switch 55-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal acquired by the temperature detection unit 35 corresponding to the electrode unit 33 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 58 via a corresponding voltage divider resistor 53 in the adapter 20. The first power supply module 58 provides DC power to the detection channel A, B, C, D, and E.

[0062] In this embodiment, the first communication unit 56 is configured to acquire digital signals output by multiple sets of ADC units 52 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage of the alternating electrical signal provided to the multiple electrode units 33 of the electrode sheet 13 according to the received digital signals. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35 corresponding to at least one electrode unit 33 in the electrode sheet 13 exceeds the preset temperature threshold (e.g., 41°C, 42°C, etc.). At this time, the voltage of the alternating electrical signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 33 of the electrode sheet 13 from becoming too hot when the alternating electrical signal is applied, causing low-temperature burns to the patient's skin. The aforementioned preset temperature threshold and preset threshold can be determined according to human safety thresholds. The first communication unit 56 is controlled by the first controller 51 and serially transmits the digital signals converted by the multiple sets of ADC units 52. In this embodiment, the preset temperature threshold can be a value within the range of 36°C-45°C.

[0063] refer to Figure 5 and Figure 6In this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30 and is configured to supply power to the first controller 51, multiple ADC units 52, and the first communication unit 56 of the adapter 20. Each electrode 13 is connected to the adapter 20 via a first connector 60, which is adapted to connect the corresponding electrode 13 to the adapter 20. Figure 1 As shown, the first connector 60 includes a first plug 61 located at the end of the first cable 15 away from the electrode plate 13 and a first socket 62 located on the adapter 20. The first plug 61 and the first socket 62 are press-type spring connectors, that is, the first connector 60 connects the adapter 20 and the electrode plate 13 by means of a connector. Each first cable 15 has 5 wires that are electrically connected to the corresponding bidirectional switch 55 in the corresponding set of bidirectional switch 55 and 4 wires that are electrically connected to the corresponding control switch 54 in the corresponding set of control switches 54. That is, each first connector 60 is electrically connected to the corresponding set of bidirectional switch 55 and the corresponding set of control switches 54 of the adapter 20 through 9 wires, and is connected to the electric field generator 30 through a corresponding alternating power line 57 of the adapter 20.

[0064] A second connector 70 is provided between the adapter 20 and the electric field generator 30, and the second connector 70 is adapted to connect the electric field generator 30 to the adapter 20. For example... Figure 1As shown, the adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 located at the end of the second cable 25 away from the first controller 51 and a second socket 72 located on the electric field generator 30. The second plug 71 and the second socket 72 are push-button spring connectors, that is, the second connector 70 connects the adapter 20 to the electric field generator 30 using a connector method. Each first connector 60, such as X1, Y1, X2, and Y2, is connected to the second connector 70 via a corresponding alternating power line 57. The first connectors 60, such as X1, Y1, X2, and Y2, are also connected to a corresponding set of control switches 54 and a corresponding set of ADC units 52, respectively. Each first connector 60 is connected to the second connector 70 and the corresponding set of ADC units 52 via a corresponding set of bidirectional switching switches 55. The second cable 25 has eight wires, including four wires 1 to 4 that are electrically connected to the corresponding alternating power lines 57 and used for transmitting alternating electrical signals, one wire 5 that is electrically connected to the data receiving line RX of the first communication unit 56, one wire 6 that is electrically connected to the data transmitting line TX of the first communication unit 56, one wire 7 that is electrically connected to the VCC power line of the first power module 58, and one wire 8 that is electrically connected to the GND line of the first power module 58. The second connector 70 is connected to the first communication unit 56 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, and the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and grounded. The VCC pin of the second connector 70 is also connected to the corresponding group of voltage-reducing resistors 53 and the corresponding group of ADC units 52 via the VCC power line of the first power module 58.

[0065] refer to Figure 5 and Figure 7The electric field generator 30 includes a second power supply module 32, a second controller 37, an AC signal generator 39, a second communication unit 38, and a set of power switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded through the GND line of the second power supply module 32. The second power supply module 32 is also connected to and supplies power to the second controller 37 and the AC signal generator 39, respectively. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 through its data receiving line RX and to the wire 6 of the second connector 70 through its data transmitting line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39, and a set of power switches 40. The second controller 37 is configured to control the opening and closing of each power switch 40 in the set of power switches 40 and adjust the relevant parameters of the alternating electrical signal applied by the AC signal generator 39 according to the relevant digital signals received from the adapter 20 by the second communication unit 38. The AC signal generator 39 is electrically connected to the conductors 1 to 4 of the second connector 70 for transmitting alternating electrical signals through the set of power switches 40. The set of power switches 40 includes multiple power switches 40, and the multiple power switches 40 are arranged one-to-one with multiple electrode plates 13. Each power switch 40 is electrically connected to a corresponding conductor 1, 2, 3, 4 in the second connector 70 for transmitting alternating electrical signals through an AC power line 41-1, 41-2, 41-3, 41-4, and is also electrically connected to the corresponding electrode plate 13 through the corresponding conductors 1, 2, 3, 4 of the second connector 70, so as to transmit an alternating electrical signal to each electrode plate 13. The AC signal generator 39 is electrically connected to the group of power supply switches 40 via multiple AC power lines 41. Specifically, the number of power supply switches 40 of the electric field generator 30 is related to the number of electrode plates 13. In this embodiment, the number of power supply switches 40 is equal to the number of electrode plates 13, and both are four. The power supply switches 40 include a first power supply switch 40-1, a second power supply switch 40-2, a third power supply switch 40-3, and a fourth power supply switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 respectively.One end of the first power supply switch 40-1 is electrically connected to the AC signal generator 39 via the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 1 for transmitting alternating electrical signals in the second connection 70 via an AC power line 41-1, and to the AC power line 57 at port X1 of the adapter 20 via the conductor 1 of the second connector 70. The AC power line 57 at port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at port X1 of the adapter 20 is electrically connected to the corresponding electrode plate 13, so as to control whether the AC signal generator 39 transmits alternating electrical signals to the electrode plate 13 electrically connected to port X1 of the adapter 20. The second power supply switch 40-2 is electrically connected at one end to the AC signal generator 39 via the AC power line 41 of the electric field generator 30, and at the other end via an AC power line 41-2 to the corresponding conductor 2 transmitting alternating electrical signals in the second connection 70. It is also electrically connected via the conductor 2 of the second connector 70 to the alternating power line 57 at port Y1 of the adapter 20. The alternating power line 57 at port Y1 of the adapter 20 is electrically connected to the first connector 60. The first connector 60 at port Y1 of the adapter 20 is electrically connected to the corresponding electrode 13, thereby controlling whether the AC signal generator 39 supplies alternating electrical signals to the electrode 13 electrically connected to port Y1 of the adapter 20. The third power supply switch 40-3 is electrically connected at one end to the AC signal generator 39 via the AC power line 41 of the electric field generator 30, and at the other end via an AC power line 41-3 to the corresponding conductor 3 transmitting alternating electrical signals in the second connection 70. It is also electrically connected via the conductor 3 of the second connector 70 to the alternating power line 57 at port X2 of the adapter 20. The alternating power line 57 at port X2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at port X2 of the adapter 20 is electrically connected to the corresponding electrode plate 13. This controls whether the AC signal generator 39 supplies alternating electrical signals to the electrode plate 13 electrically connected to port X2 of the adapter 20. The fourth power supply switch 40-4 is electrically connected at one end to the AC signal generator 39 via the AC power line 41 of the electric field generator 30, and at the other end via an AC power line 41-4 to the corresponding wire 4 in the second connection 70 for transmitting alternating electrical signals. It is also electrically connected via the wire 4 of the second connector 70 to the alternating power line 57 at port Y2 of the adapter 20. The alternating power line 57 at port Y2 of the adapter 20 is electrically connected to the first connector 60. The first connector 60 at port Y2 of the adapter 20 is electrically connected to the corresponding electrode plate 13, so as to control whether the AC signal generator 39 transmits alternating electrical signals to the electrode plate 13 electrically connected to port Y1 of the adapter 20.

[0066] The following will refer to Figures 3 to 5 The working principle of the tumor electric field therapy system 100 in this embodiment is described in detail.

[0067] Specifically, when it is necessary to detect the temperature at each electrode unit 33 of a certain electrode plate 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the multiple bidirectional switching switches 55 electrically connected to the electrode plate 13 to turn on the signal acquisition terminal 1 and turn off the signal input terminal 2, so as to disconnect the alternating electrical signal applied to the electrode plate 13; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the control switches 54 electrically connected to the electrode plate 13 to turn on sequentially in a time-division manner. At this time, the temperature detection signals collected by each temperature detection unit 35 corresponding to each electrode unit 33 in each row of the electrode plate 13 can be collected sequentially in a time-division manner through the multiple detection channels A, B, C, D, E of a group of ADC units 52 corresponding to the electrode plate 13. Each detection channel A, B, C, D, and E of each ADC unit 52 in each row simultaneously acquires only the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 in the same row of the electrode plate 13. The temperature detection signal can be characterized by voltage value. Only one of the four control switches 54 in the group corresponding to the electrode plate 13 can be turned on at any given time, while the other three are turned off. All five bidirectional switching switches 55 in the group corresponding to the ADC unit 52 are switched to their respective signal acquisition terminals 1 so that each dual-purpose signal line 19 of the electrode plate 13 is electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding ADC unit 52, thus enabling conduction. With this configuration, the ADC unit 52 can acquire the voltage values ​​of all temperature detection units 35 corresponding to each electrode unit 33 in the same row of the electrode plate 33 that are shorted by a grounding wire 18 corresponding to the turned-on control switch 54.

[0068] Specifically, when control switch 54-1 is closed, and control switches 54-2, 54-3, and 54-4 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to electrode units 33-1 to 33-5 in the first row group are energized, while the temperature detection units 35 corresponding to electrode units 33-6 to 33-20 in the remaining row groups are de-energized. In this group of ADC units 52, the temperature detection units 35 corresponding to electrode units 33-1, 33-6, 33-11, and 33-16 are short-circuited on the first detection channel A. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-1 is grounded at the signal terminal 35-2 of the measurement unit 35, while the grounding terminals 35-1 of the temperature detection units 35 corresponding to electrode units 33-6, 33-11, and 33-16 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, it will not affect the resistance value of the temperature detection unit 35 corresponding to electrode unit 33-1. Therefore, only the temperature detection unit 35 corresponding to electrode unit 33-1 is effectively operating on the first detection channel A of this group of ADC units 52, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-1. Similarly, the voltage value collected on the second detection channel B of this group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-2. The voltage value acquired on the third detection channel C of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-3. The voltage value acquired on the fourth detection channel D of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-4. The voltage value acquired on the fifth detection channel E of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-5.

[0069] When control switch 54-2 is closed, and control switches 54-1, 54-3, and 54-4 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to electrode units 33-6 to 33-10 in the second row group are energized, while the temperature detection units 35 corresponding to electrode units 33-1 to 33-5 and electrode units 33-11 to 33-20 in the other row groups are de-energized. In this group of ADC units 52, electrode units 33-1, 33-6, 33-11, and 33-16 are short-circuited on the first detection channel A. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-6 is grounded, while the grounding terminals 35-1 of the temperature detection units 35 corresponding to electrode units 33-1, 33-11, and 33-16 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, the resistance value of the temperature detection unit 35 corresponding to electrode unit 33-6 will not be affected. Therefore, only the temperature detection unit 35 corresponding to electrode unit 33-6 is effectively operating on the first detection channel A of this group of ADC units 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-6. Similarly, the voltage value collected on the second detection channel B of this group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-7. The voltage value acquired on the third detection channel C of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-8. The voltage value acquired on the fourth detection channel D of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-9. The voltage value acquired on the fifth detection channel E of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-10.

[0070] When control switch 54-3 is closed, and control switches 54-1, 54-2, and 54-4 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to electrode units 33-11 to 33-15 in the third row group are energized, while the temperature detection units 35 corresponding to electrode units 33-1 to 33-10 and electrode units 33-16 to 33-20 in the other rows are de-energized. In this group of ADC units 52, electrode units 33-1, 33-6, 33-11, and 33-16 are short-circuited on the first detection channel A. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-11 is grounded, while the grounding terminals 35-1 of the temperature detection units 35 corresponding to electrode units 33-1, 33-6, and 33-16 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, the resistance value of the temperature detection unit 35 corresponding to electrode unit 33-11 will not be affected. Therefore, only the temperature detection unit 35 corresponding to electrode unit 33-11 is effectively operating on the first detection channel A of this group of ADC units 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-11. Similarly, the voltage value collected on the second detection channel B of this group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-12. The voltage value acquired on the third detection channel C of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-13. The voltage value acquired on the fourth detection channel D of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-14. The voltage value acquired on the fifth detection channel E of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-15.

[0071] When control switch 54-4 is closed, control switches 54-1, 54-2, and 54-3 are all open, and the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, the fourth bidirectional switching switch 55-4, and the fifth bidirectional switching switch 55-5 are all switched to their respective signal acquisition terminals 1. The temperature detection units 35 corresponding to electrode units 33-16 to 33-20 in the fourth row group are energized, while the temperature detection units 35 corresponding to electrode units 33-1 to 33-15 in the other row groups are de-energized. The temperature detection units 35 corresponding to electrode units 33-1, 33-6, 33-11, and 33-16 in the first detection channel A of the ADC unit 52 in this group are short-circuited. At signal terminal 35-2 of ADC unit 52, only the ground terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-16 is grounded, while the ground terminals 35-1 of the temperature detection units 35 corresponding to electrode units 33-1, 33-6, and 33-11 are disconnected. Furthermore, each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, which does not affect the resistance value of the temperature detection unit 35 corresponding to electrode unit 33-16. Therefore, only the temperature detection unit 35 corresponding to electrode unit 33-16 is effectively operating on the first detection channel A of this ADC unit 52. At this time, the temperature detection signal (voltage value) acquired by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-16. Similarly, the voltage value acquired on the second detection channel B of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-17. The voltage value acquired on the third detection channel C of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-18. The voltage value acquired on the fourth detection channel D of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-19. The voltage value acquired on the fifth detection channel E of this ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-20.

[0072] Therefore, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can acquire the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of a certain electrode piece 13 by controlling a set of bidirectional switching switches 55 and a set of control switches 54, all of which are electrically connected to a certain electrode piece 13. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to be connected to the corresponding temperature sampling points (unlabeled) at the same time, and the switching state of the corresponding control switches 54 is configured so that the temperature detection signals detected by the corresponding temperature detection units 35 in each row group are sampled based on the corresponding temperature sampling points (unlabeled). Similarly, the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 of other electrode pieces 13 can be obtained.

[0073] The first controller 51 or the second controller 37, multiple ADC units 52, and multiple bidirectional switching switches 55 can automatically perform operations through pre-programmed program code. For example, the first controller 51 or the second controller 37 first controls all bidirectional switching switches 55 in the corresponding group to switch to the signal acquisition terminal 1, so that the signal acquisition terminals 1 of these bidirectional switching switches 55 are all turned on and the signal input terminals 2 are all turned off, so that the dual-purpose signal lines 19 of the corresponding electrode plates 13 are electrically connected to the corresponding group of ADC units 52. Then, the control switch 54-1 in the corresponding group of control switches 54 is closed, and the remaining control switches 54-2 to 54-4 in the group of control switches 54 are turned off. During this period, the group of control switches 54... Each detection channel A, B, C, D, and E of the ADC unit 52 acquires the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 in the first row of the electrode sheet 13, converts them into digital signals, and stores them in a separately provided memory. Then, after a preset time interval, the first controller 51 or the second controller 37 closes control switch 54-2 in the group of control switches 54, and opens control switches 54-1, 54-3, and 54-4 in the group of control switches 54. During this period, each detection channel A, B, C, D, and E of the ADC unit 52 acquires the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 in the second row of the electrode sheet 13. By sequentially and individually turning on each control switch 54 in the group of control switches 54, the temperature detection signals of all temperature detection units 35 on the electrode sheet 13 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature detection units 35 on at least one pair of electrode sheets 13 can be obtained.

[0074] It should be noted that in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a set of bidirectional switching switches 55 and a set of control switches 54 electrically connected to a certain electrode plate 13 to collect temperature detection signals of the temperature detection units 35 corresponding to some electrode units 33 of the electrode plate 13 during the same temperature acquisition period. For example, when only the first bidirectional switching switch 55-1 is switched to its signal acquisition terminal 1, the control switch 54-1 can be closed first, and the control switches 54-2, 54-3 and 54-4 can be opened. At this time, only the temperature detection unit 35 corresponding to the electrode unit 33-1 of the first row group is energized. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is shorted on the first detection channel A of the ADC unit 52 of this group. Therefore, the ADC unit 52 of this group will detect the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1. Then, the control switch 54-2 is closed, and the control switches 54-1, 54-2 and 54-4 are opened. When control switches 53 and 54-4 are both open, the ADC unit 52 will detect the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-6. Then, control switch 54-3 is closed, and control switches 54-1, 54-2, and 54-4 are all open. The ADC unit 52 will then detect the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-11. Finally, control switch 54-4 is closed, and control switches 54-1, 54-2, and 54-3 are all open. The ADC unit 52 will then detect the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-16. Therefore, within the same acquisition time period, only the temperature detection signal of the temperature detection unit 35 corresponding to one column of electrode units 33 can be sampled. Similarly, the temperature detection signals of the temperature detection units 35 corresponding to other columns of electrode units 33 can be sampled during other acquisition time periods. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal line 19 corresponding to each column group to the corresponding temperature sampling point (unlabeled), and the switching state of the control switch 54 is configured so that the temperature detection signal detected by each temperature detection unit 35 in each column group is sampled separately. It should be noted that in some other embodiments, the temperature detection signals of the temperature detection units 35 corresponding to two, three, or four column groups of electrode units 33 can also be sampled within the same acquisition time period, which will not be described in detail here.

[0075] Specifically, when it is necessary to apply an alternating electrical signal to each electrode unit 33 of an electrode plate 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal input terminal 2 of each of the multiple bidirectional switching switches 55 electrically connected to the electrode plate 13 to be turned on and the signal acquisition terminal 1 to be turned off, and controls a power supply switch 40 electrically connected to the electrode plate 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electrical signal to each electrode unit 33 of the electrode plate 13 through the alternating power supply line 57, and the magnitude of the applied alternating electrical signal voltage or current is adjustable. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to be simultaneously connected to the alternating power supply line 57, so that the electrode units 33 of at least two column groups are simultaneously applied with alternating electrical signals based on the alternating power supply line 57.

[0076] It should be noted that in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a group of bidirectional switching switches 55 electrically connected to a certain electrode plate 13 to apply alternating electrical signals to some electrode units 33 of the electrode plate 13 at the same time period. For example, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal input terminal 2 of the first bidirectional switching switch 55-1 of the group of bidirectional switching switches 55 electrically connected to the electrode plate 13 to be turned on and the signal acquisition terminal 1 to be turned off, and controls a power supply switch 40 electrically connected to the electrode plate 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply alternating electrical signals to the first column of electrode units 33-1, 33-6, 33-11 and 33-16 of the electrode plate 13 through the alternating power line 57, and the magnitude of the applied alternating electrical signal voltage or current is adjustable. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal line 19 corresponding to each column group to the alternating power supply line 57, so that the electrode unit 33 of each column group is simultaneously subjected to an alternating electrical signal based on the alternating power supply line 57. It should be noted that in some other embodiments, alternating electrical signals can also be applied to two, three, or four column groups of electrode units 33 simultaneously within the same time period, which will not be described in detail here.

[0077] It should be noted that in this embodiment, the control switch 54, which is electrically connected to each of the multiple grounding lines 18 of the electrode plate 13, and the bidirectional switching switch 55, which is electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode plate 13, are both located in the adapter 20. However, in other embodiments, the control switch 54, which is electrically connected to the grounding line 18, and the bidirectional switching switch 55, which is electrically connected to the dual-purpose signal line 19, may also be located on the electrode plate 13 or in the electric field generator 30, which will not be elaborated further here. In addition, the ADC unit 52 located in the adapter 20 may also be located in the electric field generator 30 and directly controlled by the second controller 37.

[0078] The tumor electric field therapy system 100 of this application can achieve real-time and comprehensive temperature monitoring of all electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 or increasing the number of wire cores in the first cable 15 electrically connected to the electrode sheet 13. Based on the obtained temperature detection signals, it can determine whether the electrode sheet 13 is qualified; or it can determine whether the temperature detection unit 35 of the electrode sheet 13 is faulty or abnormal based on the obtained temperature detection signals, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature detection units 35; or, if the electrode sheet is qualified, it can identify the electrode sheet type based on the obtained temperature detection signals; or, if the electrode sheet is qualified, it can determine whether the electrode units 33 of the electrode sheet 13 are overheated based on the obtained temperature detection signals, and further control the alternating electrical signals applied to the electrode sheet 13 or the corresponding column of electrode units 33 of the electrode sheet 13, thus avoiding low-temperature burns to the patient's skin during tumor treatment through the electrode sheet 13. Furthermore, the substrate 31 of the electrode sheet 13 of this application is electrically connected to the signal terminal 35-2 of the same electrode unit 33 and its corresponding temperature detection unit 35 via the same dual-purpose signal line 19. This allows for the transmission of both alternating current signals and DC signals for temperature signal acquisition, as well as the acquired temperature detection signals, via the dual-purpose signal line 19. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid on the substrate, reducing the wiring difficulty of the substrate 31, simplifying the manufacturing process, reducing the weight of the substrate 31, and lowering manufacturing costs. The electrode sheet 13 of this application can also switch between applying alternating current signals for tumor treatment and transmitting DC signals for temperature acquisition and transmitting the acquired temperature detection signals through a combination of a control switch 54 electrically connected to the grounding line 18 and a bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19.

[0079] Specifically, when it is necessary to apply alternating electrical signals to the patient through the electrode units 33 of a certain electrode pad 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls all the control switches 54 in a set of control switches 54 corresponding to the electrode pad 13 to be disconnected, and at the same time controls all the bidirectional switching switches 55 in a set of bidirectional switching switches 55 corresponding to the electrode pad 13 to be switched to their respective signal input terminals 2, so that the signal acquisition terminals 1 of these bidirectional switching switches 55 are all disconnected and the signal input terminals 2 are all turned on, so that each dual-purpose signal line 19 of the electrode pad 13 is electrically connected to an alternating power supply line 57 corresponding to the electrode pad 13 of the adapter 20, thereby transmitting the alternating electrical signals to each electrode unit 33 of the electrode pad 13.When the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of the detected electrode plate 13 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue generating alternating electrical signals with increased voltage or current amplitude, or with constant voltage or current amplitude, and then transmits them to the corresponding counter electrode plate 13 through a corresponding alternating power line 57 of the adapter 20, so that the counter electrode plate 13 continues to be applied with alternating electrical signals; when the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of the detected electrode plate 13 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20. When the electric field generator 30 can reduce the voltage or current of the alternating signal generated by the AC signal generator 39 through the second controller 37, it can further reduce the voltage or current of the alternating signal applied to the electrode 13. When the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 of a certain electrode 13 is detected to be greater than the preset temperature threshold, the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode 13 to disconnect through the second controller 37, so as to stop applying the alternating signal to the electrode 13. Alternatively, the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 electrically connected to the electrode 13. All signals are switched from their signal input terminal 2 to signal acquisition terminal 1. That is, all bidirectional switching signal acquisition terminals 1 of a set of bidirectional switching switches 55 electrically connected to the electrode 13 are turned on and all signal input terminals 2 are turned off, thereby stopping the application of alternating electrical signals to the electrode 13. Alternatively, when the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode 13 is detected to be greater than a preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls a bidirectional switching switch electrically connected to the electrode unit 33 of the electrode 13. 55 switches from its signal input terminal 2 to its signal acquisition terminal 1, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 simultaneously controls the remaining bidirectional switching switches 55 that are electrically connected to the electrode units 33 in different columns from the electrode units 33 whose temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold, so as to stop applying alternating electrical signals to all electrode units 33 in the column where the temperature detection signals of the electrode sheet 13 exceed the preset temperature threshold, and continue to apply alternating electrical signals to the other column electrode units 33 whose temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold.This enables a tumor electric field therapy system 100 based on an alternating electrical signal application control method using a temperature detection signal.

[0080] This application provides an electrode temperature detection method, applied to the electrode 13 or the tumor electric field therapy system 100 described above, with reference to... Figure 8 As shown, it includes the following steps:

[0081] Step 210: Control the switching unit so that at least one column group of the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point via the dual-purpose signal line 19.

[0082] Specifically, a bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13, and at the same time connect the DC electrical signal applied to the signal terminal 35-2 of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13.

[0083] Furthermore, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode plate 13 is switched from its end connected to the alternating current signal to its end connected to the direct current signal, that is, the bidirectional switching switch 55 electrically connected to the electrode plate 13 is switched from its signal input terminal 2 to its signal acquisition terminal 1; or, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode plate 13 is switched from the on state to the off state, and at the same time, the signal terminal 35-2 of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode plate 13 is switched from the off state to the on state.

[0084] Step 220: Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0085] Specifically, the control switch 54, which is electrically connected to the ground terminal 35-1 of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13, is turned on in a time-division manner to obtain the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13.

[0086] In some embodiments, when the dual-use signal line 19 corresponding to each column group is connected to the corresponding temperature sampling point, the control switch 54 corresponding to each row group is controlled, including: controlling the control switch 54 corresponding to each row group to close sequentially, so as to sample the analog temperature signal of each electrode unit 33 in each column group respectively.

[0087] In other embodiments, when the dual-use signal lines 19 corresponding to at least two column groups are simultaneously connected to the corresponding temperature sampling points, the control switch 54 corresponding to each row group is controlled, including: controlling the control switch 54 corresponding to each row group to close sequentially, so as to sample the analog temperature signal of the corresponding electrode unit 33 in each row group respectively.

[0088] The electrode temperature detection method of this application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and can determine whether the temperature detection units of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified and needs to be replaced based on the obtained temperature detection signals of all temperature detection units of the electrode sheet; it can also determine whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals of all temperature detection units of the electrode sheet when all temperature detection units of the electrode sheet are normal, and then control the alternating electrical signal applied to the electrode sheet or each electrode unit of the electrode sheet; it can also identify the electrode sheet type when the temperature detection signals of each temperature detection unit of the electrode sheet are normal.

[0089] The first controller 51 or electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of this application embodiment is provided with a preset threshold, a first preset temperature, a second preset temperature and a preset temperature threshold, wherein the first preset temperature is lower than the second preset temperature and the second preset temperature is lower than the preset temperature threshold.

[0090] Reference Figure 9 As shown, this application also provides a method for detecting abnormal temperature of an electrode sheet, which includes the following steps:

[0091] Step 210: Control the switching unit so that at least one column group of the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point via the dual-purpose signal line 19.

[0092] Step 220: Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point, so as to determine the temperature detection signal at each electrode unit 33 in each electrode sheet 13.

[0093] Step 230: Determine whether there is any abnormality in electrode plate 13 based on the temperature detection signal.

[0094] In some embodiments, step 230, which determines whether the electrode plate 13 is abnormal based on the temperature detection signal, specifically includes the following steps:

[0095] Step 231: Compare the temperature at each electrode unit 33 in the corresponding electrode sheet 13 with a preset temperature threshold based on the temperature detection signal. Specifically, the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 can be compared with the preset temperature threshold.

[0096] Step 232: Determine whether the temperature of the electrode sheet 13 is abnormal based on the comparison results. Specifically, determine whether there is any temperature abnormality in each electrode unit 33 within the electrode sheet 13 based on the comparison results.

[0097] The comparison results in step 232 include those that do not exceed a preset temperature threshold and those that exceed a preset temperature threshold. "Does not exceed the preset temperature threshold" includes "far below the preset temperature threshold" and "close to the preset temperature threshold." The preset temperature threshold is 40℃-42℃. Optionally, the preset temperature threshold is 40.5℃-41.5℃. Optionally, the preset temperature threshold is 41℃-41.5℃. Optionally, the preset temperature threshold is 41℃.

[0098] The process of determining whether the temperature of the electrode sheet 13 is abnormal based on the comparison results in step 232 is as follows: if the temperature at any electrode unit 33 in the corresponding electrode sheet 13 exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is abnormal. If the temperature at all electrode units 33 in the corresponding electrode sheet 13 does not exceed the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is not abnormal.

[0099] In other embodiments, step 230, which determines whether the electrode plate 13 is abnormal based on the temperature detection signal, specifically includes the following steps:

[0100] Step 233: If it is determined from the temperature detection signal that any electrode unit 33 in the corresponding electrode sheet 13 is abnormal or has a fault, the electrode sheet 13 is deemed unqualified.

[0101] Specifically, based on the temperature detection signals detected by the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13, it is determined whether the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are abnormal or faulty; then, based on whether the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are abnormal or faulty, it is determined whether the electrode sheet 13 is qualified. Specifically, if the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are abnormal or faulty, the electrode sheet 13 is determined to be unqualified; if the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are not abnormal or faulty, the electrode sheet 13 is determined to be qualified.

[0102] In some other embodiments, step 230, which involves determining whether the electrode plate 13 is abnormal based on the temperature detection signal, specifically includes the following steps:

[0103] Step 234: If it is determined from the temperature detection signal that there is an abnormal or faulty electrode unit 33 in the corresponding electrode sheet 13, determine the number of abnormal or faulty electrode units 33.

[0104] Step 235: If the number of abnormal or faulty electrode units 33 reaches a preset threshold, it is determined that the electrode sheet 13 needs to be replaced.

[0105] Specifically, based on the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13, it is determined whether there is any abnormality or malfunction in the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13; then, based on whether there is any abnormality or malfunction in the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13, it is determined whether the electrode sheet 13 needs to be replaced.

[0106] For example, if the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or malfunctioning, and the number of abnormal or malfunctioning temperature detection units 35 exceeds a preset threshold, it is determined that the electrode sheet 13 needs to be replaced; if the number of abnormal or malfunctioning temperature detection units 35 in the electrode sheet 13 does not exceed the preset threshold, it is determined that the electrode sheet 13 does not need to be replaced. The preset threshold is 20% of the total number of temperature detection units 35 in the electrode sheet 13.

[0107] Reference Figure 10 As shown, this application also provides a control method for a tumor electric field therapy system, which includes the following steps:

[0108] Step 210: Control the switching unit so that at least one column group of the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point via the dual-purpose signal line 19.

[0109] Step 220: Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point, so as to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13.

[0110] Step 240: Control the intensity of the alternating electrical signal applied to the electrode unit 33 according to the temperature detection signal.

[0111] Specifically, when it is determined that the electrode plate 13 does not need to be replaced, the alternating electrical signal applied to each electrode unit 33 in the electrode plate 13 is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode plate 13. That is to say, steps 234-235 can be added between steps 240 and 220.

[0112] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33 based on the temperature detection signal in step 240 specifically includes the following steps:

[0113] Step 241: Compare the temperature at each electrode unit 33 in the electrode sheet 13 with the preset temperature threshold based on the temperature detection signal.

[0114] Step 242: Control the strength of the alternating current signal based on the comparison results.

[0115] In some embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242 specifically includes:

[0116] Step 2421: If the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, stop applying alternating electrical signals to the electrode units 33 of the electrode sheet 13. Specifically, stop applying alternating electrical signals to the electrode units 33 of the electrode sheet 13 when any of the acquired temperature detection signals of all electrode units 33 exceeds the preset temperature threshold. Continue applying alternating electrical signals to all electrode units 33 of the electrode sheet 13 when none of the acquired temperature detection signals of any of the electrode units 33 exceed the preset temperature threshold.

[0117] In some embodiments, stopping the application of alternating electrical signals to the electrode units 33 of the electrode sheet 13 in step 2421 specifically includes: stopping the application of alternating electrical signals to all electrode units 33 of the electrode sheet 13; or stopping the application of alternating electrical signals to all electrode units 33 in the column group of electrode units 33 that exceed a preset temperature threshold in the electrode sheet 13.

[0118] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33 in the column group containing electrode units 33 that exceed the preset temperature threshold, alternating electrical signals continue to be applied to electrode units 33 in other columns of the electrode sheet 13. The intensity of the alternating electrical signals applied to the electrode units 33 in other columns of the electrode sheet 13 is adjustable. For example, all electrode units 33 in the electrode sheet 13 whose temperature detection signals do not exceed the preset temperature threshold and are in a different column from the electrode units 33 whose temperature detection signals exceed the preset temperature threshold are still subject to alternating electrical signals, and these signals are adjustable.

[0119] In other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242 specifically includes:

[0120] Step 2422: If the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the preset temperature threshold, and if the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode units 33 of the electrode sheet 13, wherein the first preset temperature is less than the preset temperature threshold.

[0121] In step 2422, the electric field strength of each column group whose alternating electrical signal strength is increased is increased by the same amount.

[0122] Step 2423: If the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the first preset temperature but is less than the second preset temperature, then the alternating electrical signal strength currently applied to the electrode unit 33 of the electrode sheet 13 remains unchanged.

[0123] Step 2424: If the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the second preset temperature but is less than the preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33 of the electrode sheet 13, wherein the second preset temperature is greater than the first preset temperature but less than the preset temperature threshold.

[0124] In step 2424, the electric field intensity of each column group whose alternating electrical signal intensity is reduced is reduced by the same amount.

[0125] For example, when the temperature detection signal is much lower than a preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13, or by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant. When the temperature detection signal is close to the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant, or by decreasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13.

[0126] In some other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242 specifically includes:

[0127] Step 2425: If the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, determine the number of over-temperature groups.

[0128] Step 2426: If the number of overheated groups exceeds a preset threshold, stop applying alternating electrical signals to all electrode units 33 of the electrode sheet 13.

[0129] Step 2427: If the number of overheated columns does not exceed the preset number threshold, stop applying alternating electrical signals to all electrode units 33 in the column where the electrode unit 33 that exceeds the preset temperature threshold is located in the electrode sheet 13.

[0130] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33 in the column group of electrode units 33 that exceed the preset temperature threshold in the electrode sheet 13, alternating electrical signals continue to be applied to electrode units 33 in other columns of the electrode sheet 13. The intensity of the alternating electrical signals applied to the electrode units 33 in other columns of the electrode sheet 13 is adjustable.

[0131] Step 2428: If the number of overheated groups does not exceed a preset threshold, and the temperature at each electrode unit 33 in the non-overheated groups does not exceed a first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode unit 33 in the non-overheated groups, wherein the first preset temperature is less than a preset temperature threshold.

[0132] In step 2428, the electric field strength of each column group whose alternating electrical signal strength is increased is increased by the same amount.

[0133] Step 2429: If the number of overheated groups does not exceed the preset number threshold, and if the temperature at at least one electrode unit 33 in the non-overheated group exceeds the first preset temperature but is less than the preset temperature threshold, then the alternating electrical signal strength currently applied to the electrode unit 33 in the non-overheated group remains unchanged.

[0134] Step 2430: If the number of overheated groups does not exceed a preset threshold, and if at least one electrode unit 33 in the non-overheated groups has a temperature that exceeds a second preset temperature but is less than a preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33 in the non-overheated groups, wherein the second preset temperature is greater than the first preset temperature but less than the preset temperature threshold.

[0135] In step 2430, the electric field intensity of each column group whose alternating electrical signal intensity is reduced is reduced by the same amount.

[0136] For example, when the temperature detection signal is much lower than a preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13, or by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant. When the temperature detection signal is close to the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant, or by decreasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13.

[0137] Reference Figure 11 As shown, this application also provides a method for identifying electrode type, which includes the following steps:

[0138] Step 210: Control the switching unit so that at least one column group of the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point via the dual-purpose signal line 19.

[0139] Step 220: Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point, so as to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13.

[0140] Step 250: Identify the type of electrode 13 based on the temperature detection signal.

[0141] Specifically, if the electrode sheet 13 is qualified or the temperature detection units 35 of the electrode sheet 13 are not abnormal or have no faults, the type of the electrode sheet 13 is identified based on the temperature detection signals detected by the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13.

[0142] This application also provides a signal control method for tumor electric field therapy, used in the tumor electric field therapy system 100 or the electrode sheet 13 described above. The method includes: combined control of a control switch 54 and a bidirectional switching switch 55 electrically connected to the electrode sheet 13 to switch each electrode unit 33 of the electrode sheet 13 between applying an alternating electrical signal and acquiring a temperature detection signal.

[0143] Reference Figure 12 As shown, this application also provides a signal control method for tumor electric field therapy, used in the above-mentioned electrode sheet 13, the method comprising:

[0144] Step 310: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the corresponding electrode sheet 13 to apply alternating electrical signals to each electrode unit 33 of the electrode sheet 13 and execute step 320;

[0145] Step 320: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to collect the temperature detection signals of each electrode unit 33 of the electrode plate 13 in a row and execute step 330;

[0146] Step 330: Determine the combined control mode of the control switch 54 and the bidirectional switching switch 55 electrically connected to the electrode 13 based on the collected temperature detection signal and execute step 340;

[0147] Step 340: Control the working state of each electrode unit 33 of the electrode sheet 13 according to the determined combination control method of control switch 54 and bidirectional switching switch 55.

[0148] The operating states of each electrode unit 33 of the electrode sheet 13 in step 340 include at least one of the following: stopping the application of alternating current signals and continuing to acquire temperature detection signals, and stopping the acquisition of temperature detection signals and continuing to apply alternating current signals. Continuing to apply alternating current signals includes continuing to apply alternating current signals by increasing the voltage or current amplitude of the currently applied alternating current signals, or continuing to apply alternating current signals by keeping the voltage or current amplitude of the currently applied alternating current signals unchanged, or continuing to apply alternating current signals by decreasing the voltage or current amplitude of the currently applied alternating current signals.

[0149] The operating state of each electrode unit 33 of the electrode sheet 13 is determined by the temperature detection signal it collects. Each electrode unit 33 of the electrode sheet 13 is divided into different regions, and each electrode unit 33 in each region can be cyclically switched between applying an alternating electrical signal and collecting a temperature detection signal by a combination of control switch 54 and bidirectional switching switch 55.

[0150] This application provides another method for detecting the temperature of electrode pads in a tumor electric field therapy system 100. Please refer to... Figure 13 As shown, the temperature detection method includes:

[0151] Step 510: Disconnect the input of the alternating electrical signal to the electrode 13, perform combined control of multiple control switches 54 and multiple bidirectional switching switches 55, and acquire the temperature detection signal of the temperature detection unit 35 of the electrode 13 corresponding to each combination.

[0152] Step 520: Sample and convert the temperature detection signal detected by each temperature detection unit 35 in the electrode 13 to obtain a digital temperature signal;

[0153] Step 530: The digital temperature signal is transmitted to the electric field generator 30 of the tumor electric field therapy system 100 so that the electric field generator 30 can determine the temperature at the corresponding electrode unit 33 based on the digital temperature signal.

[0154] In step 510, the combined control of multiple control switches 54 and multiple bidirectional switching switches 55 specifically includes:

[0155] Step 511: Set all bidirectional switching switches 55 to signal acquisition terminal 1 to connect the signal terminals 35-2 of each temperature detection unit 35 corresponding to each electrode unit 33 with the corresponding ADC unit 52.

[0156] Step 512: Sequentially close one of the multiple control switches 54 individually to collect the temperature detection signals detected by each temperature detection unit 35 corresponding to each electrode unit 33 in the corresponding row group.

[0157] In step 512, closing one of the multiple control switches 54 in sequence and at different times enables the detection channel that is electrically connected to each temperature detection unit 35 in the row group corresponding to the closed control switch 54 to be turned on.

[0158] Thus, the temperature detection signals of each temperature detection unit 35 in each row group can be obtained sequentially, and then processed by the adapter 20 or the electric field generator 30 to obtain the temperature of all electrode units 33 on the electrode sheet 13, thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0159] The tumor electric field therapy system 100 of this application embodiment can also perform temperature detection on individual electrode units 33 as needed. The specific process for temperature detection of a specific electrode unit 33 on the electrode sheet 13 is as follows: disconnect the input of the alternating current signal; place the bidirectional switching switch 55 corresponding to the column group containing the electrode unit 33 requiring individual temperature measurement at signal acquisition terminal 1; place the remaining bidirectional switching switches 55 at signal input terminal 2; simultaneously turn on and ground the control switch 54 corresponding to the row group containing the electrode unit 33 requiring individual temperature measurement; and turn off all remaining control switches 54. Thus, the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 requiring individual temperature measurement can be sampled to obtain the temperature of the electrode unit 33. For example, if the electrode unit 33 requiring individual temperature measurement is electrode unit 33-1, then the bidirectional switch 55-1 corresponding to electrode unit 33-1 is set to signal acquisition terminal 1, and the remaining bidirectional switches (55-2 to 55-5) are all set to signal input terminal 2; simultaneously, the control switch 18-1 corresponding to electrode unit 33-1 is closed and grounded, and the remaining control switches (18-2 to 18-4) are all opened. Thus, the temperature of electrode unit 33-1 can be detected.

[0160] This application embodiment also provides another method for applying alternating electrical signals for tumor electric field therapy, applied to the aforementioned tumor electric field therapy system 100. Please refer to... Figure 14 As shown, the method for applying the alternating electrical signal includes:

[0161] Step 610: Determine the region (1-5) in which the electrode unit 33, to which the alternating electrical signal needs to be applied, is located in the electrode sheet 13;

[0162] Step 611: Combine multiple control switches 54 and multiple bidirectional switching switches 55 that are electrically connected to the electrode plate 13 to apply alternating electrical signals.

[0163] In step 611, the combination of multiple control switches 54 and multiple bidirectional switching switches 55 electrically connected to electrode plate 13 specifically refers to:

[0164] Step 612: Disconnect all control switches 54 that are electrically connected to electrode plate 13;

[0165] Step 613: Determine the column group of the electrode units 33 in the areas where the alternating electrical signal needs to be applied, based on the area where the electrode units 33 are located.

[0166] Step 614: Determine the bidirectional switching switch 55 that is electrically connected to the electrode units 33 in those column groups according to the column groups where the alternating electrical signal needs to be applied;

[0167] Step 615: Control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to be applied with alternating current signal to connect the electrode unit 33 that needs to be applied with alternating current signal to the alternating power supply line 57 to apply alternating current signal; at the same time, control the remaining bidirectional switching switches 55 to disconnect the electrical connection between each electrode unit 33 in the area where alternating current signal does not need to be applied and the alternating power supply line 57, thereby stopping the application of alternating current signal.

[0168] In step 615, "connecting the electrode unit that needs to be applied with an alternating signal to the alternating power line 57 to apply the alternating signal, and disconnecting the electrical connection between the electrode unit 33 in the area where no alternating signal needs to be applied and the alternating power line 57 to stop applying the alternating signal" is achieved by placing the bidirectional switching switch 55, which is electrically connected to the electrode unit 33 in the column group corresponding to the area (1-5) in the electrode sheet 13 where the alternating signal needs to be applied, at its signal input terminal 2, and placing all the bidirectional switching switches 55, which are electrically connected to the electrode unit 33 in the remaining column groups, at the signal acquisition terminal 1.

[0169] The first controller 51 or electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of this application embodiment is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2 and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0170] This application also provides a method for applying alternating electrical signals based on temperature detection signals, used in the aforementioned tumor electric field therapy system 100. Please refer to... Figure 15 As shown, the application method includes:

[0171] Step 710: Activate the tumor electric field therapy system 100;

[0172] Step 711: Combine the control switch 54 (also called grounding switch) and the bidirectional switching switch 55 that are electrically connected to the corresponding electrode plate 13 to apply alternating electrical signals to each electrode unit 33 of the electrode plate 13;

[0173] Step 712: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13;

[0174] Step 713: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 714. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 715.

[0175] Step 714: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 712;

[0176] Step 715: Determine whether there is an electrode unit 33 with a temperature exceeding the second preset temperature t2; if there is no electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 716; if there is an electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 717.

[0177] Step 716: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 712;

[0178] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, proceed to step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, proceed to step 719.

[0179] Step 718: Continue to apply alternating current signals to all electrode units 33 of electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and return to step 712;

[0180] Step 719: Determine the number of overheated areas and proceed to step 720, wherein the overheated area is the area containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-overheated area is the area where the temperature of all electrode units does not exceed the preset temperature threshold t0.

[0181] Step 720: Determine whether the number of overheated areas exceeds the preset number threshold. If the number of overheated areas exceeds the preset number threshold, proceed to step 721. If the number of overheated areas does not exceed the preset number threshold, proceed to step 724.

[0182] Step 721: Stop applying alternating electrical signals to each electrode unit 33 of the electrode sheet 13 and proceed to step 722;

[0183] Step 722: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13 and execute step 723;

[0184] Step 723: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 711. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 722.

[0185] Step 724: Distinguish between overheated and non-overheated regions based on whether there is an electrode unit 33 with a temperature exceeding the preset temperature threshold t0. If the region is an overheated region, proceed to step 725; if the region is a non-overheated region, proceed to step 726.

[0186] Step 725: Stop applying alternating electrical signals to each electrode unit 33 in the over-temperature region and proceed to step 731;

[0187] Step 726: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, execute step 727. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, execute step 728.

[0188] Step 727: Continue to apply alternating current signals to each electrode unit 33 in the non-over-temperature region of electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and execute step 731;

[0189] Step 728: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, proceed to step 729. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, proceed to step 730.

[0190] Step 729: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area of ​​electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and execute step 731;

[0191] Step 730: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area of ​​electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and execute step 731;

[0192] Step 731: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to reacquire the temperature of each electrode unit 33 of the electrode plate 13 and select to execute step 732 or step 734. The temperature of each electrode unit 33 of the electrode plate 13 includes the temperature of each electrode unit 33 in the over-temperature region and the temperature of each electrode unit 33 in the non-over-temperature region.

[0193] Step 732: Determine whether the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1, execute step 733. If there is a temperature in each electrode unit 33 in the overheated area that exceeds the first preset temperature t1, return to step 731.

[0194] Step 733: Re-determine the area as a non-overheated zone and proceed to step 734;

[0195] Step 734: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, execute step 735. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, execute step 736.

[0196] Step 735: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 712;

[0197] Step 736: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, execute step 737. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, execute step 738.

[0198] Step 737: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 712;

[0199] Step 738: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the preset temperature threshold t0. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the preset temperature threshold t0, proceed to step 739. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the preset temperature threshold t0, return to step 719.

[0200] Step 739: Continue to apply alternating electrical signals to each electrode unit 33 in the non-overheated area by reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712.

[0201] Specifically, the process in step 711 where the combined control is electrically connected to the control switch 54 and the bidirectional switching switch 55 of the corresponding electrode sheet 13 to apply alternating electrical signals to each electrode unit 33 of the electrode sheet is as follows:

[0202] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0203] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that electrically connects each electrode unit 33 to the alternating power supply line 57; or

[0204] Disconnect all control switches 54 that are electrically connected to the corresponding electrode 13, and simultaneously switch all bidirectional switching switches 55 that are electrically connected to the corresponding electrode 13 to their respective signal input terminals 2.

[0205] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 712, 722, and 731 is as follows:

[0206] The bidirectional switching switch 55, electrically connected to the electrode plate 13, is switched from its end that applies alternating electrical signals to each electrode unit 33 to its end that allows each electrode unit 33 to acquire temperature data. The control switch 54, electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 of the electrode plate 13, is closed sequentially in a time-sharing manner to acquire the temperature of each electrode unit 33 of the electrode plate 13; or

[0207] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, switches all its signal input terminals 2, which apply alternating electrical signals to each electrode unit 33, to its signal acquisition terminal 1. It also sequentially closes the control switch 54, which is electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 of the electrode plate 13, to obtain the temperature of each electrode unit 33; or

[0208] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, switches the electrode plate 13 from being electrically connected to the alternating power line 57 for each electrode unit 33 to being electrically connected to the temperature detection unit 35 corresponding to each electrode unit 33 and the corresponding analog-to-digital converter 53. The control switch 54, which is sequentially closed at different times to connect to the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode plate 13, is then used to obtain the temperature of each electrode unit 33 of the electrode plate 13; or

[0209] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, switches the electrode plate 13 from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals. The control switch 54, which is electrically connected to the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode plate 13, is closed in a time-sharing sequence to obtain the temperature of each electrode unit 33 of the electrode plate 13.

[0210] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40℃-40.3℃, preferably 40.2℃. The second preset temperature in steps 715, 728, and 736 is 40.4℃ to 40.6℃, preferably 40.5℃; the preset temperature threshold in steps 717 and 738 is 41℃ to 41.5℃, preferably 41℃; the preset quantity threshold in step 720 is preferably 2.

[0211] The process of continuing to apply the alternating electrical signal as described in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is as follows:

[0212] Disconnect the control switch 54 electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to conduct the alternating electrical signal transmission path electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0213] Disconnect the control switch 54 electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to switch from its respective signal acquisition terminal 1 to its respective signal input terminal 2, so as to continue applying alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0214] The control switch 54, which is electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 to which the alternating current signal needs to be continuously applied, is disconnected. Simultaneously, the signal input terminals 2 of the bidirectional switching switches 55, which are electrically connected to the electrode unit 33 to which the alternating current signal needs to be continuously applied, are electrically connected to the alternating power supply line 57, thereby continuing to apply the alternating current signal to the electrode unit 33 to which the alternating current signal needs to be continuously applied; or

[0215] Disconnect the control switch 54 electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals so that its respective signal input terminal 2 is closed and signal acquisition terminal 1 is disconnected, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0216] The control switch 54, which is electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue to apply alternating electrical signals, is disconnected. At the same time, the bidirectional switching switch 55, which is electrically connected to the electrode unit 33 that needs to continue to apply alternating electrical signals, is controlled to switch the electrode unit 33 that needs to continue to apply alternating electrical signals from transmitting temperature detection signals to applying alternating electrical signals.

[0217] The increase in the voltage or current amplitude of the currently applied alternating current signal in steps 714, 727, and 735 specifically involves boosting the voltage of the currently applied alternating current signal by increasing the DC voltage amplitude by 0.03V per second.

[0218] The method of continuing to apply the alternating current signal by reducing the voltage or current amplitude of the currently applied alternating current signal as described in steps 718, 730, and 739 specifically means continuing to apply the alternating current signal by reducing the voltage amplitude of the currently applied alternating current signal by 5V for 3 minutes.

[0219] The process of stopping the application of alternating electrical signals to each electrode unit 33 of the electrode sheet 13 as described in step 721 is as follows:

[0220] The bidirectional switching switch 55, which controls the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57, disconnects the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57; or

[0221] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, is switched from the end that applies alternating electrical signals to each electrode unit 33 to the end that allows each electrode unit 33 to acquire temperature; or

[0222] The bidirectional switching switch 55, which is electrically connected to the electrode 13, switches all signals from its signal input terminal 2, which applies alternating electrical signals to each electrode unit 33, to its signal acquisition terminal 1; or

[0223] The bidirectional switching switch 55, which is electrically connected to the electrode 13, switches the electrode 13 from being electrically connected to the alternating power line 57 in each electrode unit 33 to being electrically connected to the temperature detection unit 35 and the corresponding analog-to-digital converter 53 in each electrode unit 33; or

[0224] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, controls each electrode unit 33 of the electrode plate 13 to switch from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals from the corresponding temperature detection unit 35.

[0225] The process of stopping the application of alternating electrical signals to each electrode unit 33 in the over-temperature region as described in step 725 is as follows:

[0226] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57, disconnects the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57; or

[0227] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, is switched from the end that applies alternating electrical signals to each electrode unit 33 in the over-temperature zone to the end that allows each electrode unit 33 in the over-temperature zone to acquire temperature data; or

[0228] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the signal input terminal 2 that applies alternating electrical signals to each electrode unit 33 in the over-temperature zone, switches all signals from the input terminal 2 to the signal acquisition terminal 1.

[0229] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the AC power line 57, switches each electrode unit 33 in the over-temperature zone from being electrically connected to its corresponding temperature detection unit 35 and its corresponding analog-to-digital converter 53; or

[0230] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, switches each electrode unit 33 in the over-temperature zone from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals from the corresponding temperature detection unit 35.

[0231] In the above control method, the tumor electric field therapy system 100 includes at least two pairs of electrode plates 13 to alternately apply alternating electric fields with different directions. Each electrode plate 13 can alternately switch between applying an alternating electric signal and transmitting a temperature detection signal.

[0232] The tumor electric field therapy system 100 of this application embodiment further includes a third preset temperature t3 in the first controller 51 or electric field generator 30 within the adapter 20. The third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. This application embodiment also provides an alternating electrical signal control method based on a temperature detection signal for use in the aforementioned tumor electric field therapy system. Figure 16 As shown, the alternating current signal control method includes:

[0233] Step 810: Activate the tumor electric field therapy system 100;

[0234] Step 811: Combine the control switch 54 (also called grounding switch) and the bidirectional switching switch 55 that are electrically connected to the corresponding electrode plate 13 to apply alternating electrical signals to each electrode unit 33 of the electrode plate 13;

[0235] Step 812: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13;

[0236] Step 813: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 814. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 815.

[0237] Step 814: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0238] Step 815: Determine whether there is an electrode unit 33 with a temperature exceeding the second preset temperature t2; if there is no electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 816; if there is an electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 817.

[0239] Step 816: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 812;

[0240] Step 817: Determine whether there is an electrode unit 33 with a temperature exceeding the third preset temperature t3. If there is no electrode unit 33 with a temperature exceeding the third preset temperature t3, proceed to step 818; if there is an electrode unit with a temperature exceeding the third preset temperature t3, proceed to step 819.

[0241] Step 818: Continue to apply alternating current signals to all electrode units 33 of electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0242] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, proceed to step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, proceed to step 821.

[0243] Step 820: Continue to apply the alternating current signal to all electrode units 33 of electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0244] Step 821: Determine the number of overheated areas and proceed to step 822, wherein the overheated area is the area containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-overheated area is the area where the temperature of all electrode units does not exceed the preset temperature threshold t0.

[0245] Step 822: Determine whether the number of overheated areas exceeds the preset number threshold. If the number of overheated areas exceeds the preset number threshold, proceed to step 823. If the number of overheated areas does not exceed the preset number threshold, proceed to step 826.

[0246] Step 823: Stop applying alternating electrical signals to each electrode unit 33 of the electrode sheet 13 and proceed to step 824;

[0247] Step 824: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13 and execute step 825;

[0248] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 811. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 824.

[0249] Step 826: Distinguish between overheated and non-overheated regions based on whether there is an electrode unit 33 with a temperature exceeding the preset temperature threshold t0. If the region is an overheated region, proceed to step 827; if the region is a non-overheated region, proceed to step 828.

[0250] Step 827: Stop applying alternating electrical signals to each electrode unit 33 in the over-temperature region and proceed to step 835;

[0251] Step 828: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, proceed to step 829. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, proceed to step 830.

[0252] Step 829: Continue to apply alternating current signals to each electrode unit 33 in the non-over-temperature region of electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and execute step 835;

[0253] Step 830: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, execute step 831. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, execute step 832.

[0254] Step 831: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area of ​​electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and execute step 835;

[0255] Step 832: Determine whether there are any electrode units 33 in the non-overheated area whose temperature exceeds the third preset temperature t3. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the third preset temperature t3, execute step 833. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the third preset temperature t3, execute step 834.

[0256] Step 833: Continue to apply alternating current signals to each electrode unit 33 in the non-over-temperature region of electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and execute step 835;

[0257] Step 834: Continue to apply alternating current signals to each electrode unit 33 in the non-over-temperature region of electrode sheet 13 in a manner that further reduces the voltage or current amplitude of the currently applied alternating current signal and proceed to step 835;

[0258] Step 835: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to reacquire the temperature of each electrode unit 33 of the electrode plate 13 and select to execute step 836 or step 838. The temperature of each electrode unit 33 of the electrode plate 13 includes the temperature of each electrode unit 33 in the over-temperature region and the temperature of each electrode unit 33 in the non-over-temperature region.

[0259] Step 836: Determine whether the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1, proceed to step 837. If there is a temperature in each electrode unit 33 in the overheated area that exceeds the first preset temperature t1, return to step 835.

[0260] Step 837: Re-determine the area as a non-overheated zone and proceed to step 838;

[0261] Step 838: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, execute step 839. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, execute step 840.

[0262] Step 839: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0263] Step 840: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, execute step 841. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, execute step 842.

[0264] Step 841: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 812;

[0265] Step 842: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the third preset temperature t3. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the third preset temperature t3, execute step 843. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the third preset temperature t3, execute step 844.

[0266] Step 843: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area by reducing the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0267] Step 844: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the preset temperature threshold t0. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the preset temperature threshold t0, proceed to step 845. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the preset temperature threshold t0, return to step 821.

[0268] Step 845: Continue to apply alternating electrical signals to each electrode unit 33 of the non-overheated region in a manner that further reduces the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812.

[0269] Specifically, the process in step 811 where the combined control is electrically connected to the control switch 54 and the bidirectional switching switch 55 of the corresponding electrode sheet 13 to apply alternating electrical signals to each electrode unit 33 of the electrode sheet is as follows:

[0270] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0271] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that electrically connects each electrode unit 33 to the alternating power supply line 57; or

[0272] Disconnect all control switches 54 that are electrically connected to the corresponding electrode 13, and simultaneously switch all bidirectional switching switches 55 that are electrically connected to the corresponding electrode 13 to their respective signal input terminals 2.

[0273] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 812, 824, and 835 is as follows:

[0274] The bidirectional switching switch 55, electrically connected to the electrode plate 13, is switched from its end that applies alternating electrical signals to each electrode unit 33 to its end that allows each electrode unit 33 to acquire temperature data. The control switch 54, electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 of the electrode plate 13, is closed sequentially in a time-sharing manner to acquire the temperature of each electrode unit 33 of the electrode plate 13; or

[0275] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, switches all its signal input terminals 2 (which apply alternating electrical signals to each electrode unit 33) to its signal acquisition terminals 1, and sequentially closes the control switches 54, which are electrically connected to the temperature detection units 35 corresponding to the electrode units 33 of the electrode plate 13, to obtain the temperature of each electrode unit 33 of the electrode plate 13; or

[0276] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, switches the electrode plate 13 from being electrically connected to the alternating power line 57 for each electrode unit 33 to being electrically connected to the temperature detection unit 35 corresponding to each electrode unit 33 and the corresponding analog-to-digital converter 53. The control switch 54, which is sequentially closed at different times to connect to the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode plate 13, is then used to obtain the temperature of each electrode unit 33 of the electrode plate 13; or

[0277] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, controls each electrode unit 33 of the electrode plate 13 to switch from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals from the corresponding temperature detection unit 35. The control switch 54, which is electrically connected to the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode plate 13, is closed in a time-sharing sequence to obtain the temperature of each electrode unit 33 of the electrode plate 13.

[0278] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40℃-40.3℃, preferably 40.2℃. The second preset temperature in steps 815, 830, and 840 is 40.4℃ to 40.6℃, preferably 40.5℃; the third preset temperature in steps 817, 832, and 842 is 40.7℃ to 40.9℃, preferably 40.8℃; the preset temperature threshold in steps 819 and 844 is 41℃ to 41.5℃, preferably 41℃; and the preset quantity threshold in step 822 is preferably 2.

[0279] The process of continuing to apply the alternating electrical signal as described in steps 814, 816, 818, 820, 829, 831, 833, 834, 839, 841, 843, and 845 is specifically as follows:

[0280] Disconnect the control switch 54 electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to conduct the alternating electrical signal transmission path electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0281] Disconnect the control switch 54 electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to switch from its respective signal acquisition terminal 1 to its respective signal input terminal 2, so as to continue applying alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0282] The control switch 54, which is electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 to which the alternating current signal needs to be continuously applied, is disconnected. Simultaneously, the signal input terminals 2 of the bidirectional switching switches 55, which are electrically connected to the electrode unit 33 to which the alternating current signal needs to be continuously applied, are electrically connected to the alternating power supply line 57, thereby continuing to apply the alternating current signal to the electrode unit 33 to which the alternating current signal needs to be continuously applied; or

[0283] Disconnect the control switch 54 electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals so that its respective signal input terminal 2 is closed and signal acquisition terminal 1 is disconnected, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0284] The control switch 54, which is electrically connected to the temperature detection unit 35 corresponding to the electrode unit 33 that needs to continue to apply alternating electrical signals, is disconnected. At the same time, the bidirectional switching switch 55, which is electrically connected to the electrode unit 33 that needs to continue to apply alternating electrical signals, is controlled to switch the electrode unit 33 that needs to continue to apply alternating electrical signals from transmitting temperature detection signals to applying alternating electrical signals.

[0285] The method of increasing the voltage or current amplitude of the currently applied alternating signal in steps 814, 829, and 839 specifically refers to boosting the voltage of the currently applied alternating signal by increasing the DC voltage amplitude by 0.03V per second before continuing to apply the alternating signal.

[0286] The method of continuing to apply the alternating current signal by reducing the voltage or current amplitude of the currently applied alternating current signal as described in steps 818, 820, 833, 834, 843, and 845 specifically refers to continuing to apply the alternating current signal by reducing the voltage amplitude of the currently applied alternating current signal by 5V for 3 minutes.

[0287] The process of stopping the application of alternating electrical signals to each electrode unit 33 of the electrode sheet 13 as described in step 823 is as follows:

[0288] The bidirectional switching switch 55, which controls the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57, disconnects the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57; or

[0289] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, is switched from the end that applies alternating electrical signals to each electrode unit 33 to the end that allows each electrode unit 33 to acquire temperature; or

[0290] The bidirectional switching switch 55, which is electrically connected to the electrode 13, switches all signals from its signal input terminal 2, which applies alternating electrical signals to each electrode unit 33, to its signal acquisition terminal 1; or

[0291] The bidirectional switching switch 55, which is electrically connected to the electrode 13, switches the electrode 13 from being electrically connected to the alternating power line 57 in each electrode unit 33 to being electrically connected to the temperature detection unit 35 and the corresponding analog-to-digital converter 53 in each electrode unit 33; or

[0292] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, controls each electrode unit 33 of the electrode plate 13 to switch from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals from the corresponding temperature detection unit 35.

[0293] The process of stopping the application of alternating electrical signals to each electrode unit 33 in the over-temperature region as described in step 827 is as follows:

[0294] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57, disconnects the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57; or

[0295] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, is switched from the end that applies alternating electrical signals to each electrode unit 33 in the over-temperature zone to the end that allows each electrode unit 33 in the over-temperature zone to acquire temperature data; or

[0296] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the signal input terminal 2 that applies alternating electrical signals to each electrode unit 33 in the over-temperature zone, switches all signals from the input terminal 2 to the signal acquisition terminal 1.

[0297] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the AC power line 57, switches each electrode unit 33 in the over-temperature zone from being electrically connected to its corresponding temperature detection unit 35 and its corresponding analog-to-digital converter 53; or

[0298] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, switches each electrode unit 33 in the over-temperature zone from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals from the corresponding temperature detection unit 35.

[0299] When the tumor electric field therapy system 100 is in standby mode before starting work, no alternating electrical signal is applied to the electrode unit 33. The first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the bidirectional switching switch 55 (55-1 to 55-5) to switch to the signal acquisition terminal 1, and the control switches 54 (54-1 to 54-4) are turned on in sequence. The ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to each row of electrode units 33 (33-1 to 33-20) in sequence.

[0300] When control switch 54-1 is turned on, control switches (54-2, 54-3, 54-4) are all turned off, and bidirectional switching switches (55-1 to 55-5) are all set to signal acquisition terminal 1, ADC unit 52 receives temperature detection signals from temperature detection units 35 corresponding to electrode units (33-1 to 33-5).

[0301] When control switch 54-2 is turned on, control switches (54-1, 54-3, 54-4) are all turned off, and bidirectional switching switches (55-1 to 55-5) are all set to signal acquisition terminal 1, ADC unit 52 receives temperature detection signals from temperature detection units 35 corresponding to electrode units (33-6 to 33-10).

[0302] When control switch 54-3 is turned on, control switches (54-1, 54-2, 54-4) are all turned off, and bidirectional switching switches (55-1 to 55-5) are all set to signal acquisition terminal 1, ADC unit 52 receives temperature detection signals from temperature detection units 35 corresponding to electrode units (33-11 to 33-15).

[0303] When control switch 54-4 is turned on, control switches (54-1, 54-2, 54-3) are all turned off, and bidirectional switching switches (55-1 to 55-5) are all set to signal acquisition terminal 1, ADC unit 52 receives temperature detection signals from temperature detection units 35 corresponding to electrode units (33-16 to 33-20).

[0304] The first controller 51 receives the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 (33-1 to 33-20) through the ADC unit 52, and transmits them to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38. Then, the second controller 37 controls or adjusts the alternating electrical signals applied to each electrode unit 33.

[0305] Although the operations are depicted in the accompanying drawings in a specific order, this should not be construed as requiring that the operations be performed in the specific order shown or in chronological order, nor should it be construed as requiring that all the operations shown be performed to obtain the desired result.

[0306] Example 2:

[0307] The main concept of the aforementioned tumor electric field therapy system 100 is that both the adapter 20 and the electric field generator 30 are equipped with an alternating power supply line 57 to control the synchronous change of the alternating electrical signal of all electrode units 33 on an electrode plate 13, such as voltage or current rising or falling simultaneously. However, it cannot simultaneously apply different alternating electrical signals, such as different magnitudes of voltage or current, to electrode units 33 in different groups. (Reference) Figures 17 to 20 The following describes another tumor electric field therapy system 100', whose main concept is the same as the tumor electric field therapy system 100 described above. The difference is that: in the adapter 20' and electric field generator 30' of this tumor electric field therapy system 100', each column of electrode units 33' on the corresponding electrode plates 13' is provided with a corresponding alternating power supply line 57', so that different alternating electrical signals, such as different voltages or currents, can be applied to different columns of electrode units 33' at the same time.

[0308] Figure 18 This is a schematic diagram of the circuit connection between an electrode 13', an adapter 20', and an electric field generator 30' in another embodiment of the present application tumor electric field therapy system 100'. The tumor electric field therapy system 100' includes: at least a pair of electrode 13', an adapter 20' connected to the electrode 13', and an electric field generator 30' connected to the adapter 20'.

[0309] The specific structure of electrode 13' is the same as that of electrode 13 described above, and will not be repeated here.

[0310] The specific construction of adapter 20' is similar to that of adapter 20 described above, except that: (Refer to...) Figure 18 and Figure 19 Each electrode 13' in the adapter 20' is equipped with 5 alternating power lines 57'. The 5 alternating power lines 57' correspond one-to-one with the 5 column electrode units 33' of each electrode 13'. Each electrode 13' is equipped with a corresponding bidirectional switching switch 55' and a grounding switch 54'. The signal input terminal 2 of the bidirectional switching switch 55' is electrically connected to a separate AC power line 57', so that the tumor electric field therapy system 100' can apply different alternating electrical signals, such as different voltages or currents, to different column electrode units 33' in each electrode 13' as needed.

[0311] The specific structure of the electric field generator 30' is similar to that of the electric field generator 30 described above, except that: (Refer to...) Figure 18 and Figure 20 Each AC power supply line 57' between the AC signal generator 39' and the adapter 20' is equipped with a power supply switch 40' to control the switching on and off of the AC signal for each column of electrode units 33' of each electrode sheet 13'.

[0312] Specifically, refer to Figure 18 and Figure 19 As shown, the adapter 20' includes: a first controller 51', multiple ADC units 52' connected to the first controller 51', multiple voltage-reducing resistors 53' and multiple control switches 54' corresponding to each of the multiple ADC units 52', multiple bidirectional switching switches 55' corresponding to each of the multiple ADC units 52', a first communication unit 56', multiple alternating power lines 57' corresponding to each of the bidirectional switching switches 55', and a first power module 58' connected to the first communication unit 56', the first controller 51', and the multiple ADC units 52'. The first power module 58' provides DC power VCC to each electronic component of the adapter 20'. The adapter 20' also includes multiple circuit lines (unlabeled), which are electrically connected to multiple grounding lines 18' and multiple dual-purpose signal lines 19' in the substrate 31' of the corresponding electrode plates 13' through the first cables 15' of the corresponding electrode plates 13'. The multiple circuit lines (unlabeled) include multiple alternating power supply lines 57' that transmit alternating electrical signals to the corresponding electrode 13' and are electrically connected to the multi-purpose signal lines 19' in the substrate 31' of the corresponding electrode 13'; multiple circuit lines (unlabeled) that are electrically connected one-to-one with the multi-purpose signal lines 19' in the substrate 31' of the corresponding electrode 13' and are used to power each temperature detection unit 35' of the electrode 13' or transmit the temperature detection signal of the electrode 13'; and multiple circuit lines (unlabeled) that are electrically connected one-to-one with the multiple grounding lines 18' in the substrate 31' of the corresponding electrode 13'. The number L of circuit lines electrically connecting adapter 20' to one electrode piece 13' is equal to the sum of the number of rows and columns of electrode units 33' of electrode piece 13'; the number H of circuit lines electrically connecting adapter 20' to X electrode pieces 13' is equal to X times the number of circuit lines electrically connecting it to a single electrode piece 13', i.e., H = XL = X × (M + N). The number of groups of control switches 54' and bidirectional switching switches 55' is related to the number of electrode pieces 13'. The number of groups of control switches 54' is the same as the number of groups of bidirectional switching switches 55', and not less than the number of electrode pieces 13'. Optionally, the number of groups of control switches 54' and bidirectional switching switches 55' is the same as the number of electrode pieces 13'.

[0313] For example, each group of control switches 54' has multiple control switches 54', which are respectively connected to the adapter 20' and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding wires 18' of a corresponding electrode piece 13', and are configured to control the on or off of the multiple grounding wires 18'. The circuit lines (unlabeled) that are each electrically connected to the multiple grounding wires 18' of the electrode piece 13' are grounded at the end closest to the control switch 54'. The number of control switches 54' in each group of control switches 54' is related to the number of grounding wires 18' of the corresponding electrode piece 13' substrate 31', and in this embodiment, the two are equal. Figure 18 As shown, in this embodiment, the multiple control switches 54' are respectively the first control switch 54-1', the second control switch 54-2', the third control switch 54-3', and the fourth control switch 54-4'. The multiple control switches 54' in the same group each control the closing or opening of the corresponding grounding wire 18' of the same electrode plate 13'. The first control switch 54-1' is used to control the opening or closing of the first grounding wire 18-1' of the corresponding electrode plate 13', and can then cooperate with the corresponding set of bidirectional switching switches 55' to control the energization and de-energization of the temperature detection units 35' corresponding to the five electrode units 33' in the first row group 33 of the electrode plate 13'; the second control switch 54-2' is used to control the opening or closing of the second grounding wire 18-2' of the electrode plate 13', and can then cooperate with the corresponding set of bidirectional switching switches 55' to control the energization and de-energization of the temperature detection units 35' corresponding to the five electrode units 33' in the second row group 33' of the electrode plate 13'; the third Control switch 54-3' is used to control the opening or closing of the third grounding wire 18-3' of the electrode plate 13', and can cooperate with the corresponding set of bidirectional switching switches 55' to control the energization and de-energization of the temperature detection units 35' corresponding to the five electrode units 33' in the third row group 33' of the electrode plate 13'; fourth control switch 54-4' is used to control the opening or closing of the fourth grounding wire 18-4' of the electrode plate 13', and can cooperate with the corresponding set of bidirectional switching switches 55' to control the energization and de-energization of the temperature detection units 35' corresponding to the five electrode units 33' in the fourth row group 33' of the electrode plate 13'. The control switches 54' can be mechanical switches, such as relays. Control switches 54' can also be electronic switches, and each control switch 54' can be opened and closed by an additional first controller 51'.

[0314] In this embodiment, all sets of control switches 54' are electronic switches. The first controller 51' is communicatively connected to the multiple sets of control switches 54', and is used to sequentially and cyclically control the opening and closing states of multiple control switches 54' in each set, thereby sequentially and individually activating each grounding wire 18' of the corresponding electrode 13' and coordinating with the switching of the corresponding bidirectional switching switch 55' to collect the patient's body surface temperature detected by all temperature detection units 35' on the electrode 13'. The number of control switches 54' in each set is not less than the number of grounding wires 18' on the substrate 31' of the corresponding electrode 13'. In this embodiment, the number of control switches 54' in each set is the same as the number of grounding wires 18' on the corresponding electrode 13'.

[0315] Each group of bidirectional switching switches 55' has multiple bidirectional switching switches 55'. The multiple bidirectional switching switches 55' in each group are respectively connected to the adapter 20' and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multi-purpose signal lines 19' of the corresponding electrode piece 13'. The number of bidirectional switching switches 55' in each group of bidirectional switching switches 55' is related to the number of multi-purpose signal lines 19' of the substrate 31' of the corresponding electrode piece 13', which is greater than or equal to the number of multi-purpose signal lines 19' of the substrate 31' of the corresponding electrode piece 13'. In this embodiment, the two are equal. Each bidirectional switch 55' has two ends labeled 1 and 2. The signal acquisition terminals 1 of multiple bidirectional switches 55' in the same group are electrically connected to the corresponding detection channels of multiple detection channels of the corresponding group of ADC units 52' through temperature sampling points (unlabeled). The signal input terminal 2 of each bidirectional switch 55' in the same group is electrically connected to the corresponding different alternating power lines 57' and is configured to control the multi-channel dual-purpose signal line 19' to connect to the corresponding different alternating power lines 57' to transmit alternating electrical signals or to connect to the corresponding detection channel of the corresponding group of ADC units 52' to receive the temperature detection signal output by the temperature detection unit 35'.

[0316] like Figure 18As shown, taking the electrical connection of one electrode piece 13' with the adapter 20' as an example, in this embodiment with 20 electrode units 33', the multiple bidirectional switching switches 55' are respectively the first bidirectional switching switch 55-1', the second bidirectional switching switch 55-2', the third bidirectional switching switch 55-3', the fourth bidirectional switching switch 55-4', and the fifth bidirectional switching switch 55-5'. The multiple bidirectional switching switches 55' in the same group each control the switching of a corresponding dual-purpose signal line 19' of the same electrode piece 13' between transmitting alternating electrical signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 55-1' is used to control the switching of the first dual-purpose signal line 19-1' of the corresponding electrode piece 13' between the alternating electrical signal output from the alternating power supply line 57-1' and the temperature detection signal, thereby controlling the conduction of each electrode unit 33' in the first column group of electrode units 33-1', 33-6', 33-11', and 33-16' of the electrode piece 13' and the conduction of each electrode unit 33' in the first column group of electrode units 33-1', 33-6', 33-11', and 33-16'. The switching between the conduction of the signal terminals 35-2' of each temperature detection unit 35' corresponding to electrode unit 33-16' and the switching between them, in conjunction with the corresponding control switches 54-1', 54-2', 54-3', and 54-4', enables the first row of electrode units 33-1', 33-6', 33-11', and 33-16' to transmit individual alternating electrical signals to the patient or to output the temperature detection data collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. Signal; The second bidirectional switching switch 55-2' is used to control the switching of the second dual-purpose signal line 19-2' of the corresponding electrode piece 13' between the alternating electrical signal output from the alternating power supply line 57-2' and the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode units 33-2', 33-7', 33-12', and 33-17' in the second column group of the electrode piece 13', and the conduction of each electrode unit 33' of the electrode units 33-2', 33-7', 33-12', and 33-17' in the second column group of the electrode piece 13'. The signal terminals 35-2' of each temperature detection unit 35' corresponding to electrode 33-17' are switched between the two and cooperate with the corresponding control switches 54-1', 54-2', 54-3', and 54-4' so that the second row of electrode units 33-2', 33-7', 33-12', and 33-17' transmit individual alternating electrical signals to the patient or output temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'.The third bidirectional switching switch 55-3' is used to control the switching of the third dual-purpose signal line 19-3' of the corresponding electrode plate 13' between the alternating electrical signal output from the alternating power supply line 57-3' and the temperature detection signal, thereby controlling the conduction of each electrode unit 33' in the third column group of the electrode plate 13', including electrode units 33-3', 33-8', 33-13', and 33-18', and the conduction of each electrode unit 33' in the third column group of the electrode plate 13'. The signal terminals 35-2' of each temperature detection unit 35' corresponding to 33-18' enable switching between the two and cooperate with the corresponding control switches 54-1', 54-2', 54-3', and 54-4', so that the third row of electrode units 33-3', 33-8', 33-13', and 33-18' can transmit individual alternating electrical signals to the patient or output temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. The fourth bidirectional switching switch 55-4' is used to control the switching of the fourth dual-purpose signal line 19-4' of the corresponding electrode plate 13' between the alternating electrical signal output from the alternating power supply line 57-4' and the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode units 33-4', 33-9', 33-14', and 33-19' in the fourth column group of the electrode plate 13', and the conduction of each electrode unit 33' of the electrode units 33-4', 33-9', 33-14', and 33-19' in the fourth column group. The signal terminals 35-2' of each temperature detection unit 35' corresponding to element 33-19' are switched between the two and cooperate with the corresponding control switches 54-1', 54-2', 54-3', and 54-4' so that the fourth column of electrode units 33-4', 33-9', 33-14', and 33-19' transmit individual alternating electrical signals to the patient or output temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52';The fifth bidirectional switching switch 55-5' is used to control the switching of the fifth dual-purpose signal line 19-5' of the corresponding electrode 13' between the alternating electrical signal output from the alternating power supply line 57-5' and the temperature detection signal, thereby controlling the conduction of each electrode unit 33' in the fifth column group of the electrode 13', including electrode units 33-5', 33-10', 33-15', and 33-20', and the conduction of each electrode unit 33' in the fifth column group. The signal terminals 35-2' of each temperature detection unit 35' corresponding to 33-20' enable the switching between the two and cooperate with the corresponding control switches 54-1', 54-2', 54-3', and 54-4' so that the fifth column of electrode units 33-5', 33-10', 33-15', and 33-20' transmit individual alternating electrical signals to the patient or output temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. When the signal input terminal 2 of each group of bidirectional switching switches 55' is turned on and the signal acquisition terminal 1 is turned off, alternating electrical signals can be transmitted to each electrode unit 33' of each column of the corresponding electrode plate 13' through different alternating power lines 57'. When the signal acquisition terminal 1 of each group of bidirectional switching switches 55' is turned on and the signal input terminal 2 is turned off, it can cooperate with each control switch 54' in the corresponding group of control switches 54' to transmit the temperature detection signals collected by the temperature detection unit 35' corresponding to each electrode unit 33' on the electrode plate 13' in a time-division manner. The aforementioned bidirectional switching switches 55' can be mechanical switches, such as relays. The bidirectional switching switches 55' can also be electronic switches, and each bidirectional switching switch 55' can be switched by an additional first controller 51'.

[0317] In this embodiment, all of the multiple sets of bidirectional switching switches 55' are electronic switches. The first controller 51' is communicatively connected to the multiple sets of bidirectional switching switches 55' and is used to control the switching of multiple bidirectional switching switches 55' in each set between their respective signal acquisition terminal 1 and signal input terminal 2, and to cooperate with the closing or opening of the corresponding control switch 54' to continuously monitor the temperature of the patient's body surface detected by all temperature detection units 35' on the electrode pad 13' or to transmit alternating electrical signals to the patient.

[0318] In this embodiment, each ADC unit 52' is electrically connected one-to-one to the signal acquisition terminals 1 of multiple bidirectional switching switches 55' in the corresponding group via multiple circuit lines (unlabeled) within the adapter 20', and is configured to receive temperature detection signals transmitted from the multi-purpose signal lines 19' of the corresponding electrode 13', and convert the temperature detection signals from analog signals to digital signals. Each ADC unit 52' includes multiple detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to a corresponding dual-purpose signal line 19' in the multi-purpose signal lines 19' via the corresponding bidirectional switching switch 55'. Figure 18 As shown, each ADC unit 52' contains five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1' via the signal acquisition terminal 1 of the first bidirectional switch 55-1'; the second detection channel B is connected to the second dual-purpose signal line 19-2' via the signal acquisition terminal 1 of the second bidirectional switch 55-2'; the third detection channel C is connected to the third dual-purpose signal line 19-3' via the signal acquisition terminal 1 of the third bidirectional switch 55-3'; the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4' via the signal acquisition terminal 1 of the fourth bidirectional switch 55-4'; and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5' via the signal acquisition terminal 1 of the fifth bidirectional switch 55-5'. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal acquired by the temperature detection unit 35' corresponding to the electrode unit 33' connected to the corresponding dual-purpose signal line 19'. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 58' via a corresponding voltage divider resistor 53' within the adapter 20'. The first power supply module 58' provides DC power to the detection channel A, B, C, D, and E.

[0319] In this embodiment, the first communication unit 56' is configured to acquire digital signals output by multiple ADC units 52' and send the digital signals to the electric field generator 30'. The electric field generator 30' is also configured to control and adjust the voltage of the alternating electrical signal provided to the multiple electrode units 33' of the electrode sheet 13' according to the received digital signals. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35' corresponding to at least one electrode unit 33' in the electrode sheet 13' exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage of the alternating electrical signal output by the electric field generator 30' can be appropriately reduced or stopped to avoid the electrode units 33' of the electrode sheet 13' from becoming too hot when the alternating electrical signal is applied, which could cause low-temperature burns to the patient's skin. The aforementioned preset threshold temperature and preset threshold can be determined according to human safety thresholds. The first communication unit 56' is controlled by the first controller 51' and serially transmits the digital signals converted by the multiple ADC units 52'. In this embodiment, the preset threshold temperature can be a value within the range of 36℃-45℃.

[0320] refer to Figure 18In this embodiment, the first power module 58' is electrically connected to the second power module 32' of the electric field generator 30', and is configured to supply power to the first controller 51', multiple ADC units 52', and the first communication unit 56' of the adapter 20'. A first connector 60' is provided between each electrode 13' and the adapter 20', and the first connector 60' is adapted to connect the corresponding electrode 13' to the adapter 20'. A second connector 70' is provided between the adapter 20' and the electric field generator 30', and the second connector 70' is adapted to connect the electric field generator 30' to the adapter 20'. The adapter 20' also includes a second cable 25' connected to the second connector 70'. The second connector 70' includes a second plug 71' located at the end of the second cable 25' away from the first controller 51' and a second socket 72' located on the electric field generator 30'. The second plug 71' and the second socket 72' are push-button spring connectors, meaning the second connector 70' connects the adapter 20' and the electric field generator 30' using a connector. Each first connector 60', such as X1, Y1, X2, and Y2, is connected to the second connector 70' via corresponding 5 AC power lines 57'. The first connectors 60', such as X1, Y1, X2, and Y2, are also connected to a corresponding set of control switches 54' and a corresponding set of ADC units 52'. Each first connector 60' is connected to the second connector 70' and the corresponding set of ADC units 52' via a corresponding set of bidirectional switching switches 55'. The second cable 25' has eight conductors, including four five-core conductors 1 to 4 that are electrically connected to the corresponding five AC power lines 57' and used to transmit different AC signals; one conductor 5 that is electrically connected to the data receiving line RX' of the first communication unit 56'; one conductor 6 that is electrically connected to the data transmitting line TX' of the first communication unit 56'; one conductor 7 that is electrically connected to the VCC power line of the first power module 58'; and one conductor 8 that is electrically connected to the GND line of the first power module 58'. The second connector 70' is connected to the first communication unit 56' via the data receiving line RX' and the data transmitting line TX'. The VCC pin of the second connector 70' is connected to the VVC power line of the first power module 58', and the GND pin of the second connector 70' is connected to the GND line of the first power module 58' and grounded. The VCC pin of the second connector 70' is also connected to the corresponding group of voltage regulators 53' and the corresponding group of ADC units 52' via the VCC power line of the first power module 58'.

[0321] refer to Figure 18 and Figure 20The electric field generator 30' includes: a second power module 32', a second controller 37', an AC signal generator 39', a second communication unit 38', and multiple sets of power switches 40'. The VCC pin of the second connector 70' is also electrically connected to the VCC power line of the second power module 32', and the GND pin of the second connector 70' is grounded through the GND line of the second power module 32'. The second power module 32' is also connected to and supplies power to the second controller 37' and the AC signal generator 39', respectively. The second communication unit 38' is electrically connected to the wire 5 of the second connector 70' through its data receiving line RX' and to the wire 6 of the second connector 70' through its data transmitting line TX', thereby enabling information exchange between the electric field generator 30' and the adapter 20'. The second controller 37' is also electrically connected to the second communication unit 38', the AC signal generator 39', and multiple sets of power supply switches 40'. The second controller 37' is configured to control the opening and closing of each power supply switch 40' in the multiple sets of power supply switches 40' and adjust the relevant parameters of different alternating electrical signals applied by the AC signal generator 39 according to the relevant digital signals received from the adapter 20' by the second communication unit 38'. The AC signal generator 39 is electrically connected to the second connector 70' via wires 1 to 4 that transmit different alternating electrical signals through the multiple sets of power supply switches 40'. Each set of power supply switches 40' includes multiple power supply switches 40', and the multiple sets of power supply switches 40' are arranged one-to-one with multiple electrode plates 13'. Each group of power supply switches 40' is electrically connected to a corresponding five-core wire 1, 2, 3, 4 in the second connector 70' via a five-core AC power cable 41-1', 41-2', 41-3', 41-4', and then electrically connected to the corresponding electrode plate 13' via the corresponding five-core wire 1, 2, 3, 4 in the second connector 70', so as to deliver different alternating electrical signals to each electrode plate 13. The AC signal generator 39' is electrically connected to multiple groups of power supply switches 40' via a five-core AC power cable 41'. Specifically, the number of groups of power supply switches 40' in the electric field generator 30' is related to the number of electrode plates 13'. In this embodiment, the number of groups of power supply switches 40' is equal to the number of electrode plates 13', and both are 4. The number of each group of power supply switches 40' is related to the number of columns of the corresponding electrode plates 13'. In this embodiment, the number of each group of power supply switches 40' is equal to the number of columns of the corresponding electrode plates 13', and both are 5. The multiple sets of power supply switches 40' include a first set of power supply switches 40-1', a second set of power supply switches 40-2', a third set of power supply switches 40-3', and a fourth set of power supply switches 40-4', which are electrically connected one-to-one with the five-core wires 1 to 4 of the second connector 70'. One end of the first set of power supply switches 40-1' is electrically connected to the AC signal generator 39' through the five-core AC power supply line 41' of the electric field generator 30'.The other end is electrically connected to the corresponding five-core wire 1 for transmitting alternating electrical signals in the second connection 70' via a five-core AC power cable 41-1', and electrically connected to the five-channel alternating power cable 57' located at port X1' of the adapter 20' via the five-core wire 1 of the second connector 70'. The five-channel alternating power cable 57' located at port X1' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' located at port X1 of the adapter 20' is electrically connected to the corresponding electrode plate 13', so as to control whether the AC signal generator 39' transmits signals to the five electrodes 13' corresponding to the five-channel alternating power cable 57' in the electrode plate 13' electrically connected to port X1 of the adapter 20'. The electrode unit 33' in the column group transmits different alternating electrical signals; one end of the second group power supply switch 40-2' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30', and the other end is electrically connected to the corresponding five-core wire 2 transmitting alternating electrical signals in the second connection 70' through a five-core AC power line 41-2', and electrically connected to the five-way alternating power line 57' located at port Y1' of the adapter 20' through the five-core wire 2 of the second connector 70', the five-way alternating power line 57' located at port Y1' of the adapter 20' is electrically connected to the first connector 60', and the first connector located at port Y1' of the adapter 20' is electrically connected to the first connector 60'. Connector 60' is electrically connected to the corresponding electrode 13' to control whether AC signal generator 39' supplies different alternating electrical signals to electrode units 33' in the five columns of the electrode 13' corresponding to the five alternating power lines 57', which are electrically connected to port Y1' of adapter 20'; one end of the third power supply switch 40-3' is electrically connected to AC signal generator 39' through the five-core AC power line 41' of electric field generator 30', and the other end is electrically connected to the corresponding five-core wire 3' for transmitting alternating electrical signals in the second connection 70' through a five-core AC power line 41-3', and connected to adapter 20' at the end through the five-core wire 3' of the second connector 70'. The five alternating power lines 57' at port X2' are electrically connected; the five alternating power lines 57' at port X2' of adapter 20' are electrically connected to the first connector 60'; the first connector 60' at port X2' of adapter 20' is electrically connected to the corresponding electrode plate 13', so as to control whether the AC signal generator 39' supplies different alternating electrical signals to the electrode units 33' in the five columns of the electrode plate 13' corresponding to the five alternating power lines 57', which are electrically connected to port X2' of adapter 20'; one end of the fourth group of power supply switches 40-4' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30'.The other end is electrically connected via a five-core AC power cable 41-4' to the corresponding five-core wire 4' transmitting alternating electrical signals in the second connection 70', and via the five-core wire 4 of the second connector 70' to the five-channel alternating power cable 57' located at port Y2' of the adapter 20'. The five-channel alternating power cable 57' located at port Y2' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' located at port Y2' of the adapter 20' is electrically connected to the corresponding electrode plate 13', so as to control whether the AC signal generator 39' transmits different alternating electrical signals to the electrode units 33' in the five columns of the electrode plate 13' corresponding to the five-channel alternating power cable 57' electrically connected to port Y1' of the adapter 20'.

[0322] The following will refer to Figures 18 to 20 The working principle of the tumor electric field therapy system 100' in this embodiment is described in detail.

[0323] It should be noted that the working principle of temperature acquisition in the tumor electric field therapy system 100' is the same as that of temperature acquisition in the tumor electric field therapy system 100, and will not be repeated here.

[0324] The working principle of applying alternating electrical signals to the tumor electric field therapy system 100' is similar to that of applying alternating electrical signals to the tumor electric field therapy system 100. The difference is that this embodiment can apply different alternating electrical signals to electrode units 33 in different columns at the same time, which is more flexible.

[0325] Specifically, when it is necessary to apply alternating electrical signals to each electrode unit 33' of a certain electrode plate 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the signal input terminal 2 of each of the multiple bidirectional switching switches 55' electrically connected to the electrode plate 13' to be turned on and the signal acquisition terminal 1 to be turned off, and controls a set of power supply switches 40' electrically connected to the electrode plate 13' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply different alternating electrical signals to each column of electrode units 33' of the electrode plate 13' through different alternating power lines 57', and the magnitude of the voltage or current of the different alternating electrical signals applied can be adjusted. That is, the switching unit (unlabeled) is configured to switch the dual-use signal line 19 corresponding to at least two column groups to different alternating power lines 57', so that each electrode unit 33 of each column group is applied with different alternating electrical signals based on different alternating power lines 57'.

[0326] It should be noted that in other embodiments, a set of bidirectional switching switches 55' electrically connected to a certain electrode piece 13' can also be controlled by the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' to apply different alternating electrical signals to some electrode units 33' of the electrode piece 13' at the same time period. For example, the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the signal input terminal 2 of the first bidirectional switch 55-1' of a group of bidirectional switches 55' electrically connected to the electrode 13' to be turned on and the signal acquisition terminal 1 to be turned off. It also controls the one power supply switch 40' corresponding to the first bidirectional switch 55-1' of a group of power supply switches 40' electrically connected to the electrode 13' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply an alternating electrical signal to the first column of electrode units 33-1', 33-6', 33-11' and 33-16' of the electrode 13' through the corresponding alternating power line 57'. The voltage or current of the applied alternating electrical signal is adjustable. It should be noted that in some other embodiments, different alternating electrical signals can be applied to two, three, or four groups of electrode units 33 simultaneously within the same time period, which will not be elaborated here.

[0327] It should be noted that in this embodiment, the control switch 54', which is electrically connected to each of the multiple grounding lines 18' of the electrode plate 13', and the bidirectional switching switch 55', which is electrically connected to each of the multiple dual-purpose signal lines 19' of the electrode plate 13', are both located in the adapter 20'. However, in other embodiments, the control switch 54', which is electrically connected to the grounding line 18', and the bidirectional switching switch 55', which is electrically connected to the dual-purpose signal lines 19', may also be located on the electrode plate 13' or in the electric field generator 30', which will not be elaborated further here. In addition, the ADC unit 52' located in the adapter 20' may also be located in the electric field generator 30' and directly controlled by the second controller 37'.

[0328] The tumor electric field therapy system 100' of this application can achieve real-time and comprehensive temperature monitoring of all electrode units 33' on the electrode sheet 13' without increasing the weight of the electrode sheet 13' or the number of wire cores in the first cable 15' electrically connected to the electrode sheet 13'. Based on the obtained temperature detection signals, it can determine whether the electrode sheet 13' is qualified; or it can determine whether the temperature detection unit 35' of the electrode sheet 13' is faulty or abnormal, and determine whether the electrode sheet 13' needs to be replaced based on the number of faulty or abnormal temperature detection units 35'; or, if the electrode sheet 13' is qualified, it can identify the electrode sheet type based on the obtained temperature detection signals; or, if the electrode sheet 13' is qualified, it can determine whether the electrode units 33' of the electrode sheet 13' are overheated based on the obtained temperature detection signals, and thus control the alternating electrical signal applied to the electrode sheet 13' or the corresponding column of electrode units 33', avoiding low-temperature burns to the patient's skin during tumor treatment via the electrode sheet 13'. Furthermore, the substrate 31' of the electrode sheet 13' of this application is electrically connected to the signal terminal 35-2' of the same electrode unit 33' and its corresponding temperature detection unit 35' simultaneously via the same dual-purpose signal line 19'. This allows for the transmission of both alternating current signals and DC signals for temperature signal acquisition, along with the acquired temperature detection signals, via the dual-purpose signal line 19'. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18', dual-purpose signal line 19') on the substrate 31', lowering the wiring complexity, simplifying the manufacturing process, reducing the weight of the substrate 31', and lowering manufacturing costs. The electrode sheet 13' of this application can also switch between applying alternating current signals for tumor treatment and transmitting DC signals for temperature acquisition and the acquired temperature detection signals through a combination of control switch 54' electrically connected to its grounding line 18' and bidirectional switching switch 55' electrically connected to the dual-purpose signal line 19'.

[0329] Specifically, when it is necessary to apply alternating electrical signals to the patient through each electrode unit 33' of a certain electrode pad 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls all the control switches 54' in a set of control switches 54' corresponding to the electrode pad 13' to be disconnected, and at the same time controls all the bidirectional switching switches 55' in a set of bidirectional switching switches 55' corresponding to the electrode pad 13' to be switched to their respective signal input terminals 2, so that the signal acquisition terminals 1 of these bidirectional switching switches 55' are all disconnected and the signal input terminals 2 are all turned on, so that each dual-purpose signal line 19' of the electrode pad 13' is electrically connected to the adapter 20' and the corresponding multi-channel alternating power supply line 57' of the electrode pad 13', thereby transmitting the same or different alternating electrical signals to each electrode unit 33' of the electrode pad 13'. When the temperature detection signals of the temperature detection units 35' corresponding to all electrode units 33' of the detected electrode 13' are much lower than the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' controls the AC signal generator 39 to continue generating alternating electrical signals with increased voltage or current amplitude, or unchanged voltage or current amplitude, through its second controller 37'. These signals are then transmitted to the corresponding counter electrode 13' through the corresponding multi-channel alternating power line 57' of the adapter 20', so that the counter electrode 13' continues to receive alternating electrical signals. When the temperature detection signals of the temperature detection units 35' corresponding to all electrode units 33' of the detected electrode 13' are lower than but close to the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' can reduce the voltage or current of the alternating electrical signals generated by the AC signal generator 39' through the second controller 37', thereby reducing... The alternating voltage or current applied to the electrode 13' is reduced; when the temperature detection signal of the temperature detection unit 35' corresponding to the electrode unit 33' of a certain electrode 13' is detected to be greater than the preset temperature threshold, the electric field generator 30' controls a set of power supply switches 40' electrically connected to the electrode 13' to disconnect through the second controller 37', so as to stop applying the alternating voltage signal to the electrode 13'; or the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' controls all the bidirectional switching switches 55' of a set of bidirectional switching switches 55' electrically connected to the electrode 13' to switch from their signal input terminal 2 to the signal acquisition terminal 1, that is, all the bidirectional switching signal acquisition terminals 1 of all the bidirectional switching switches 55' of a set of bidirectional switching switches 55' electrically connected to the electrode 13' are turned on and all the signal input terminals 2 are turned off, thereby stopping the application of the alternating voltage signal to the electrode 13';Alternatively, when the temperature detection signal of a temperature detection unit 35' corresponding to an electrode unit 33' of a certain electrode plate 13' is detected to be greater than a preset temperature threshold, the second controller 37' of the electric field generator 30' controls a set of power supply switches 40' electrically connected to the electrode plate 13' to remain on, and the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' controls a bidirectional switching switch 55' electrically connected to the electrode unit 33' of the electrode plate 13' to switch from its signal input terminal 2 to its signal acquisition terminal 1, and the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' simultaneously controls the electrode unit 33' whose temperature detection signal does not exceed the preset temperature threshold and is in a different column from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold. The remaining bidirectional switching switches 55' electrically connected to electrode unit 33' remain electrically connected to their respective signal input terminals 2. This stops applying alternating electrical signals to all electrode units 33' in the column where the temperature detection signal of electrode unit 33' exceeds a preset temperature threshold, and continues to apply alternating electrical signals to the remaining columns of electrode units 33' where the temperature detection signal does not exceed the preset temperature threshold. The alternating electrical signals applied to the remaining columns of electrode units 33' can be the same or different. For example, columns whose temperature detection signals do not exceed the preset temperature threshold but are closer to it are treated with a reduced voltage or current amplitude, while columns whose temperature detection signals do not exceed the preset temperature threshold but are further away from it are treated with a increased voltage or current amplitude. This achieves a tumor electric field therapy system 100' with an alternating electrical signal application control method based on temperature detection signals.

[0330] It should be noted that the alternating electrical signal application method, electrode temperature detection method, electrode temperature anomaly detection method, control method, and electrode type identification method of the tumor electric field therapy system 100' in this embodiment are similar to the control method of the aforementioned tumor electric field therapy system 100. The difference is that the tumor electric field therapy system 100' in this embodiment can also apply different alternating electrical signals, such as different voltages or currents, to the electrode units 33' in each region (i.e., each column group) simultaneously according to the temperature of the electrode units 33' in each region, to prevent the electrode units 33' in the corresponding region from exceeding the preset temperature threshold, so as to apply the electric field continuously for a long time and improve the treatment effect.

[0331] Specifically, the tumor electric field therapy system 100' of this embodiment can adopt... Figure 8 The electrode temperature detection method shown determines the temperature at each electrode unit 33' in electrode 13'. For details, please refer to [reference needed]. Figure 8 This will not be elaborated upon here.

[0332] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 9 The method for detecting abnormal temperature of electrode 13' shown can be used to determine whether there is an abnormality. Please refer to the following for details. Figure 9 This will not be elaborated upon here.

[0333] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 21 The control method of the tumor electric field therapy system shown controls the intensity of the alternating electrical signal applied to the electrode unit 33', specifically including the following steps:

[0334] Step 210': Control the switching unit to connect the dual-use signal line 19' corresponding to at least one column group of the corresponding electrode sheet 13' to the corresponding temperature sampling point.

[0335] Step 220': Control the control switch 54' corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33' based on the corresponding temperature sampling point, so as to determine the temperature detection signal of each electrode unit 33' in each electrode sheet 13'.

[0336] Step 240': Control the intensity of the alternating electrical signal applied to electrode unit 33' based on the temperature detection signal.

[0337] Specifically, when it is determined that the electrode plate 13' does not need to be replaced, the alternating electrical signal applied to each electrode unit 33' in the electrode plate 13' is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35' corresponding to each electrode unit 33' in the electrode plate 13'.

[0338] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33' based on the temperature detection signal in step 240' specifically includes the following steps:

[0339] Step 241': Compare the temperature at each electrode unit 33' in the electrode sheet 13' with the preset temperature threshold based on the temperature detection signal.

[0340] Step 242': Control the strength of the alternating current signal based on the comparison results.

[0341] In some embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242' specifically includes:

[0342] Step 2421': If the temperature at at least one electrode unit 33' exceeds a preset temperature threshold, stop applying alternating electrical signals to the electrode units 33' of the electrode sheet 13'. Specifically, stop applying alternating electrical signals to the electrode units 33' of the electrode sheet 13' when any of the acquired temperature detection signals of all electrode units 33' exceeds the preset temperature threshold. Continue applying alternating electrical signals to all electrode units 33' of the electrode sheet 13' when none of the acquired temperature detection signals of any of the electrode units 33' exceed the preset temperature threshold.

[0343] In some embodiments, stopping the application of alternating electrical signals to the electrode units 33' of the electrode sheet 13' in step 2421' specifically includes: stopping the application of alternating electrical signals to all electrode units 33' of the electrode sheet 13'; or stopping the application of alternating electrical signals to all electrode units 33' in the column group of electrode units 33' that exceed a preset temperature threshold in the electrode sheet 13'.

[0344] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33' in the column group containing electrode units 33' that exceed the preset temperature threshold, alternating electrical signals continue to be applied to electrode units 33' in other columns of the electrode sheet 13'. The intensity of the alternating electrical signals applied to the electrode units 33' in other columns of the electrode sheet 13' is adjustable. For example, all electrode units 33' in the electrode sheet 13' whose temperature detection signal does not exceed the preset temperature threshold and are in a different column from the electrode units 33' whose temperature detection signal exceeds the preset temperature threshold are still subject to alternating electrical signals. The alternating electrical signals applied to different columns can be the same or different; for example, the voltage or current amplitude of the alternating electrical signal applied to columns closer to but not exceeding the preset temperature threshold is smaller, and vice versa.

[0345] In other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242' specifically includes:

[0346] Step 2422': If the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the preset temperature threshold, and if the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode units 33' of the electrode sheet 13', wherein the first preset temperature is less than the preset temperature threshold.

[0347] In step 2422', the increase in electric field intensity corresponding to each column group whose alternating electrical signal intensity is increased can be the same or different, that is, they can be adjusted separately. For example, the voltage or current amplitude of the alternating electrical signal applied to the column group with the lower highest temperature is larger, and vice versa.

[0348] Step 2423': If the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33' in the electrode sheet 13' exceeds the first preset temperature but is less than the second preset temperature, then the alternating electrical signal strength currently applied to the electrode unit 33' of the electrode sheet 13' remains unchanged.

[0349] In step 2423', maintaining the alternating electrical signal strength currently applied to electrode unit 33' specifically includes: maintaining the alternating electrical signal strength currently applied to the first target column group, wherein the first target column group is the column group where the temperature at electrode unit 33' exceeds a first preset temperature but is less than a second preset temperature. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the column group whose temperature exceeds the first preset temperature but is less than the second preset temperature can be maintained, while the voltage or current amplitude of the alternating electrical signal corresponding to the other column groups can still be adjusted according to the temperature of the respective column group.

[0350] Step 2424': If the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33' in the electrode sheet 13' exceeds the second preset temperature but is less than the preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33' of the electrode sheet 13'.

[0351] In step 2424', reducing the intensity of the alternating electrical signal applied to the electrode unit 33' specifically includes: reducing the intensity of the alternating electrical signal applied to the electrode unit 33' of the second target column group, wherein the second target column group is a column group where the temperature at the electrode unit 33' exceeds a second preset temperature but is less than a preset temperature threshold. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the column group whose temperature exceeds the second preset temperature but is less than the preset temperature threshold can be reduced, and the reduced amplitude can be the same or different, while the voltage or current amplitude of the alternating electrical signal corresponding to the other column groups can still be adjusted according to the temperature of the corresponding column group, for example, maintained or increased.

[0352] For example, when the temperature detection signal is much lower than the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode plate 13' by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13'. The voltage or current amplitude of the alternating electrical signal applied to different columns may be the same or different. Alternatively, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode plate 13' by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13' unchanged. The voltage or current amplitude of the alternating electrical signal applied to only some columns may remain unchanged. When the temperature detection signal approaches the preset temperature threshold, the alternating electrical signal continues to be applied to each electrode unit 33' of the electrode plate 13' in a manner that keeps the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13' constant. This can be done by keeping the voltage or current amplitude of the alternating electrical signal applied to only some columns constant, or by reducing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13'. The voltage or current amplitude of the alternating electrical signal applied to different columns can be the same or different.

[0353] In some other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242' specifically includes:

[0354] Step 2425': If the temperature at at least one electrode unit 33' exceeds a preset temperature threshold, determine the number of over-temperature groups.

[0355] Step 2426': If the number of overheated groups exceeds a preset threshold, stop applying alternating electrical signals to all electrode units 33' of electrode sheet 13'.

[0356] Step 2427': If the number of over-temperature groups does not exceed the preset number threshold, stop applying alternating electrical signals to all electrode units 33' in the column where the electrode unit 33' that exceeds the preset temperature threshold is located in the electrode sheet 13'.

[0357] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33' in the column group containing electrode units 33' that exceed the preset temperature threshold, alternating electrical signals continue to be applied to electrode units 33' in other columns of the electrode sheet 13'. The intensity of the alternating electrical signals applied to the electrode units 33' in other columns of the electrode sheet 13' is adjustable. For example, all electrode units 33' in the electrode sheet 13' whose temperature detection signal does not exceed the preset temperature threshold and are in a different column from the electrode units 33' whose temperature detection signal exceeds the preset temperature threshold are still subject to alternating electrical signals. The alternating electrical signals applied to different columns can be the same or different; for example, the voltage or current amplitude of the alternating electrical signal applied to columns closer to but not exceeding the preset temperature threshold is smaller, and vice versa.

[0358] Step 2428': If the number of overheated groups does not exceed a preset threshold, and the temperature at each electrode unit 33' in the non-overheated groups does not exceed a first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode unit 33' of the non-overheated groups, wherein the first preset temperature is less than a preset temperature threshold.

[0359] In step 2428', the increase in electric field intensity corresponding to each column group whose alternating electrical signal intensity is increased can be the same or different, that is, they can be adjusted separately. For example, the voltage or current amplitude of the alternating electrical signal applied to the column group with the lower highest temperature is larger, and vice versa.

[0360] Step 2429': If the number of overheated groups does not exceed the preset number threshold, and if the temperature at at least one electrode unit 33' in the non-overheated group exceeds the first preset temperature but is less than the preset temperature threshold, then the alternating electrical signal strength currently applied to the electrode unit 33' in the non-overheated group remains unchanged.

[0361] In step 2429', maintaining the alternating electrical signal strength currently applied to electrode unit 33' specifically includes: maintaining the alternating electrical signal strength currently applied to the first target column group, wherein the first target column group is the column group where the temperature at electrode unit 33' exceeds a first preset temperature but is less than a preset temperature threshold. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the column group whose temperature exceeds the first preset temperature but is less than the preset temperature threshold can be maintained, while the voltage or current amplitude of the alternating electrical signal corresponding to the other column groups can still be adjusted according to the temperature of the respective column group.

[0362] Step 2430': If the number of overheated groups does not exceed a preset threshold, and if at least one electrode unit 33' in the non-overheated groups has a temperature that exceeds a second preset temperature but is less than a preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33' in the non-overheated groups, wherein the second preset temperature is greater than the first preset temperature but less than the preset temperature threshold.

[0363] In step 2430', reducing the intensity of the alternating electrical signal applied to the electrode unit 33' specifically includes: reducing the intensity of the alternating electrical signal applied to the electrode unit 33' of the second target column group, wherein the second target column group is a column group where the temperature at the electrode unit 33' exceeds a second preset temperature but is less than a preset temperature threshold. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the column group whose temperature exceeds the second preset temperature but is less than the preset temperature threshold can be reduced, and the reduced amplitude can be the same or different, while the voltage or current amplitude of the alternating electrical signal corresponding to the other column groups can still be adjusted according to the temperature of the corresponding column group, for example, maintained or increased.

[0364] For example, when the temperature detection signal is much lower than the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode plate 13' by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13'. The voltage or current amplitude of the alternating electrical signal applied to different columns may be the same or different. Alternatively, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode plate 13' by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13' unchanged. The voltage or current amplitude of the alternating electrical signal applied to only some columns may remain unchanged. When the temperature detection signal approaches the preset temperature threshold, the alternating electrical signal continues to be applied to each electrode unit 33' of the electrode plate 13' in a manner that keeps the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13' constant. This can be done by keeping the voltage or current amplitude of the alternating electrical signal applied to only some columns constant, or by reducing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode plate 13'. The voltage or current amplitude of the alternating electrical signal applied to different columns can be the same or different.

[0365] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 11 The electrode type identification method shown identifies the type of electrode 13'. For details, please refer to [link / reference]. Figure 11 This will not be elaborated upon here.

[0366] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 22The signal control method for tumor electric field therapy shown combines the control switch 54' and the bidirectional switching switch 55', which are electrically connected to the electrode sheet 13', to switch each electrode unit 33' of the electrode sheet 13' between applying an alternating electrical signal and acquiring a temperature detection signal.

[0367] Reference Figure 22 As shown, the method includes:

[0368] Step 310': Combine the control switch 54' and the bidirectional switching switch 55' that are electrically connected to the corresponding electrode sheet 13' to apply alternating electrical signals to each electrode unit 33' of the electrode sheet 13' and execute step 320';

[0369] The application of alternating electrical signals to each electrode unit 33' of electrode sheet 13' in step 310' specifically includes: simultaneously applying the same or different alternating electrical signals to the electrode units 33' of some or all of all column groups.

[0370] Step 320': Combine the control switch 54' and the bidirectional switching switch 55' that are electrically connected to the electrode plate 13' to collect the temperature detection signals of each electrode unit 33' of the electrode plate 13' in a row and execute step 330';

[0371] The temperature detection signals of each electrode unit 33' of the row-collecting electrode sheet 13' in step 320' specifically include: sampling the temperature detection signals of all electrode units 33' of some or all row groups in all row groups in sequence during the same sampling time period; or sampling the temperature detection signals of some electrode units 33' of some or all row groups in all row groups in sequence during the same sampling time period.

[0372] Step 330': Determine the combined control mode of the control switch 54' and the bidirectional switching switch 55' electrically connected to the electrode 13' based on the collected temperature detection signal and execute step 340';

[0373] Step 340': Control the working state of each electrode unit 33' of the electrode sheet 13' according to the determined combination control method of control switch 54' and bidirectional switching switch 55'.

[0374] The operating states of each electrode unit 33' of the electrode sheet 13' in step 340' include at least one of the following: stopping the application of alternating current signals and continuing to acquire temperature detection signals, and stopping the acquisition of temperature detection signals and continuing to apply alternating current signals. Continuing to apply alternating current signals includes: continuing to apply alternating current signals by increasing the voltage or current amplitude of the currently applied alternating current signal, or continuing to apply alternating current signals by maintaining the voltage or current amplitude of the currently applied alternating current signal unchanged, or continuing to apply alternating current signals by decreasing the voltage or current amplitude of the currently applied alternating current signal. The methods of continuing to apply alternating current signals for different column groups can be the same or different.

[0375] The operating state of each electrode unit 33' of electrode sheet 13' is determined by the temperature detection signal it acquires. Each electrode unit 33' of electrode sheet 13' is divided into different regions. By combining control switch 54' and bidirectional switching switch 55', each electrode unit 33' in each region can be cyclically switched between applying an alternating current signal and acquiring a temperature detection signal. When applying an alternating current signal, different regions can be the same or different.

[0376] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 13 The electrode temperature detection method shown detects the temperature of electrode 13'. For details, please refer to [link / reference needed]. Figure 13 This will not be elaborated upon here.

[0377] The tumor electric field therapy system 100' of this embodiment can adopt... Figures 14-16 The method of applying alternating electrical signals for tumor electric field therapy shown applies alternating electrical signals to electrode 13'. The difference is that the alternating electrical signals applied to different columns can be the same or different. The details will not be elaborated here.

[0378] This application also provides a tumor electric field therapy system 100 or 100', comprising: at least one pair of the aforementioned electrode pads 13 or 13'; an electric field generator 30 or 30', which generates alternating power and transmits the alternating power to each electrode pad 13 or 13' via an alternating power line 57 or 57'; and a control unit (such as a first controller 51 or 51' or a second controller 37 or 37', etc.), which configures at least one of the switching states of a control switch 54 or 54' and the switching states of a switching unit (unlabeled) to sample the analog temperature signal detected by the corresponding temperature detection unit 35 or 35' in each row group based on the corresponding temperature sampling point (unlabeled), or to control the electrode units 33 or 33' of at least one column group to be applied with alternating electrical signals based on the alternating power line 57 or 57'.

[0379] This application also provides a tumor treatment device (not shown), including: the aforementioned tumor electric field therapy system 100 or 100'.

[0380] This application also provides a computer-readable storage medium storing a computer program thereon, which, when executed by a processor, implements the aforementioned electrode temperature detection method; or the aforementioned electrode abnormality detection method; or the aforementioned control method for a tumor electric field therapy system; or the aforementioned electrode type identification method.

[0381] This application also provides an adapter 20 or 20' for tumor electric field therapy, including a first memory (not shown) and a first controller 51 or 51'. The first memory (not shown) stores a computer program, which, when executed by the first controller 51 or 51', implements the aforementioned electrode temperature detection method; or the aforementioned electrode abnormality detection method; or the aforementioned control method for the tumor electric field therapy system; or the aforementioned electrode type identification method.

[0382] This application also provides an electric field generator 30 or 30' for tumor electric field therapy, including a second memory (not shown) and a second controller 37 or 37'. The second memory (not shown) stores a computer program, which, when executed by the second controller 37 or 37', implements the aforementioned electrode temperature detection method; or the aforementioned electrode abnormality detection method; or the aforementioned control method for the tumor electric field therapy system; or the aforementioned electrode type identification method.

[0383] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and not to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application, and they should all be covered within the scope of the claims and specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A tumor electric field treatment system, comprising: The electrode sheet comprises a plurality of electrode units and a plurality of temperature detection units, each of the electrode units is capable of applying an alternating electric signal, each of the temperature detection units is arranged corresponding to one of the electrode units for detecting the temperature at the corresponding electrode unit, and the signal end of each of the temperature detection units is short-circuited with the corresponding electrode unit, wherein the plurality of temperature detection units are configured as a plurality of row groups and a plurality of column groups in circuit, the ground ends of the temperature detection units in the same row group are short-circuited to the same ground line, the ground ends of the temperature detection units in different row groups are connected in parallel through different ground lines, the signal ends of the temperature detection units in the same column group are short-circuited to the same dual-purpose signal line, and the signal ends of the temperature detection units in different column groups are connected in parallel through different dual-purpose signal lines. An electric field generator is provided with an alternating electric signal and a second controller, the second controller is configured to switch the communication of each of the dual-purpose signal lines to a corresponding temperature sampling point or an alternating power supply line, so as to (1) in the case that each of the dual-purpose signal lines is communicated to the temperature sampling point, sequentially turn on each of the ground lines to make the temperature detection signals detected by each of the temperature detection units be sampled based on the corresponding temperature sampling point; and (2) in the case that each of the dual-purpose signal lines is communicated to the alternating power supply line, transmit the alternating electric signal to each of the electrode units through each of the dual-purpose signal lines. The electrode sheet is provided with a plurality of bidirectional switching switches, each of the dual-purpose signal lines is connected in series with a corresponding bidirectional switching switch, the bidirectional switching switch is provided with a signal acquisition end connected with a temperature sampling point and a signal input end connected with the alternating power supply line, and the second controller controls the bidirectional switching switch to turn on the signal acquisition end or the signal input end. The electrode sheet is further provided with a plurality of control switches, each of the ground lines is connected in series with a corresponding control switch and grounded through the corresponding control switch, and the second controller controls the turn-on and turn-off of each of the control switches.

2. The tumor electric field therapy system of claim 1, wherein, An ADC unit is provided, the ADC unit is configured to sample the temperature detection signals of each of the temperature detection units through each of the temperature sampling points and convert the sampled temperature detection signals into digital signals, and the second controller is configured to determine the temperature at the corresponding electrode unit according to the digital temperature signals output by the ADC unit.

3. The tumor electric field treatment system of claim 2, wherein, The ADC unit is arranged in the electric field generator.

4. The tumor electric field therapy system of claim 1, wherein, The second controller is further configured to determine at least one of the following conditions based on the sampled temperature detection signals: (1) whether the electrode sheet is qualified; (2) whether there is a fault in the temperature detection units of the electrode sheet; (3) whether there is an anomaly in the temperature detection units of the electrode sheet; (4) whether the electrode sheet needs to be replaced; (5) the type of the electrode sheet; and (6) whether there is an over-temperature in the electrode units of the electrode sheet.

5. The tumor electric field therapy system of claim 4, wherein, In the case that the electrode sheet is qualified, the second controller determines whether the type of the electrode sheet and / or whether there is an over-temperature in the electrode units of the electrode sheet.

6. The tumor electric field therapy system of claim 1, wherein, ​ 7. The tumor electric field treatment system of claim 6, wherein, ​ 8. The tumor electric field treatment system of claim 1, wherein, Each of the dual-purpose signal lines is connected to the same alternating power supply line, and the strength of the alternating electric signal output by the alternating power supply line is adjustable.

9. The tumor electric field treatment system of claim 1, wherein, Each of the dual-purpose signal lines is connected to different alternating power supply lines, and the strength of the alternating electric signal output by the different alternating power supply lines is adjustable.

10. An electrode sheet temperature detection method characterized by comprising: The method is applied to the tumor electric field therapy system according to any one of claims 1-9, and the method comprises: connecting each of the dual-purpose signal lines to the temperature sampling point; sequentially and individually turning on each of the ground lines so that the temperature detection signal detected by each of the temperature detection units is sampled based on each corresponding temperature sampling point.

11. An electrode sheet abnormality detection method characterized by comprising: The method is applied to the tumor electric field therapy system according to any one of claims 1-9, and the method comprises: connecting each of the dual-purpose signal lines to the temperature sampling point; sequentially and individually turning on each of the ground lines so that the temperature detection signal detected by each of the temperature detection units is sampled based on each corresponding temperature sampling point; determining whether the electrode sheet is abnormal based on each temperature detection signal.

12. The method of claim 11, wherein, The way of determining whether the electrode sheet is abnormal based on each temperature detection signal is: comparing each temperature detection signal with a preset temperature threshold value; when there is an electrode unit in the electrode sheet whose temperature exceeds the preset temperature threshold value, determining that the temperature of the electrode sheet is abnormal; or when there is no electrode unit in the electrode sheet whose temperature exceeds the preset temperature threshold value, determining that the temperature of the electrode sheet is not abnormal. The method further comprises:

13. The method of claim 12, wherein, when it is determined that there is an abnormal electrode unit in the electrode sheet, determining that the electrode sheet is unqualified; or when it is determined that there is no abnormal electrode unit in the electrode sheet, determining that the electrode sheet is qualified. The method further comprises:

14. The method of claim 12, wherein, determining the number of abnormal electrode units in the electrode sheet; when the number of abnormal electrode units exceeds a preset threshold value, determining that the electrode sheet needs to be replaced; or when the number of abnormal electrode units does not exceed the preset threshold value, determining that the electrode sheet does not need to be replaced. The preset threshold value is 20% of the total number of electrode units of the electrode sheet.

15. The method of claim 14, wherein, ​

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