Full-automatic microorganism rapid identification drug sensitivity analysis device and analysis method

By introducing a cleaning component and a gas storage box into the microbial identification and drug sensitivity analysis device, and utilizing the combination of high-speed gas and a suction hood, contaminants on the surface of the light-emitting plate and the detection card are cleaned, solving the problem of decreased accuracy caused by contamination in the optical detection system and improving detection accuracy and reliability.

CN121314972AInactive Publication Date: 2026-01-13PAIER MEDICAL (SHENZHEN) CO LTD
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Patent Information

Application Number
CN202511395795.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-28
Publication Date
2026-01-13
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In existing microbial identification and antimicrobial susceptibility testing instruments, the optical detection system suffers from decreased detection accuracy due to internal environmental contamination.

Method used

A fully automated rapid microbial identification and drug sensitivity analysis device was designed, comprising a cleaning component and a gas storage box. Through high-speed gas injection and the combination of a suction hood, contaminants on the surface of the light-emitting plate and the detection card are cleaned, forming a parabolic motion trajectory to concentrate and collect contaminants and prevent re-adhesion.

Benefits of technology

This effectively avoids contaminants affecting the reliability of detection and analysis results, improves detection accuracy and reliability, ensures beam transmittance and optical path accuracy, and reduces the risk of contaminants on the surface of the light-emitting plate and detection card.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of microbiological detection, and particularly discloses a full-automatic microbiological rapid identification and drug sensitivity analysis device which comprises a cleaning assembly; a gas storage box; and a second driving part is installed on the vertical plate, the guide frame is installed at the output end of the second driving part, and the guide frame is connected with the cleaning assembly between the vertical plate and the installation base. A plurality of cleaning assemblies are used for cleaning the surface of the light-emitting plate and the two faces of the detection card in the downward moving process, pollutants attached to the surface of the light-emitting plate and the two faces of the detection card are cleaned away, when the collecting mechanism moves to the collecting position, the collecting mechanism stops moving, and at the moment, the light-emitting plate, the protective cylinder, the detection card, the protective cylinder and the collecting mechanism are located on the same straight line; after the light-emitting plate emits light to illuminate the detection card, the acquisition mechanism acquires and analyzes information on the detection card, so that the influence of pollutants on the reliability of a detection analysis result is effectively avoided, and the detection precision is improved.
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Description

Technical Field

[0001] This invention relates to the field of microbial detection technology, and in particular to a fully automated rapid microbial identification and drug sensitivity analysis device and method. Background Technology

[0002] Microbial identification and drug susceptibility testing instruments are key equipment in modern clinical microbiology testing. Their main function is to rapidly and accurately identify various pathogens (such as Gram-negative bacteria, Gram-positive bacteria, Enterococci, and fungi) and simultaneously perform antimicrobial susceptibility testing. The test results from these instruments provide crucial etiological evidence for clinicians to develop precise anti-infective treatment plans.

[0003] With technological advancements, fully automated microbial identification and antimicrobial susceptibility testing instruments have evolved into high-end equipment integrating automation, intelligence, and advanced microbial testing methods. They enable high-throughput, rapid identification and antimicrobial susceptibility analysis of the vast majority of common clinical bacteria, significantly improving testing efficiency and result reliability. For example, in the prior art, Chinese invention patent CN114107039B discloses a microbial antimicrobial susceptibility analyzer. This instrument features an information device movably mounted within the instrument body and located on one side of a card plate device. This information device collects information from the test plates on the card plate device. A heating device is also located within the instrument body to control the internal temperature. The movable card plate device transports the test plates to the information collection point of the information device for data acquisition. The information device can also move to the test plates on the card plate device to collect information, resulting in a high degree of automation. This replaces manual transfer of test plates, thereby improving the efficiency of microbial antimicrobial susceptibility analysis. The heating device controls the internal temperature environment, promoting microbial growth and thus improving the accuracy of microbial antimicrobial susceptibility analysis.

[0004] However, after in-depth analysis, the aforementioned existing technical solutions still have significant drawbacks. Specifically, their information acquisition process relies on a light-emitting element illuminating the sample points on the detection plate, and then the acquisition mechanism (such as an optical sensor or camera) receiving the signal. In actual use, various mechanical components inside the instrument inevitably generate tiny dust and particulate matter during long-term operation. Especially under the air convection (wind guide) effect caused by the operation of the heating device, this dust and particulate matter is more likely to be suspended in the air and eventually adhere to the surfaces of key optical components, especially the light-emitting surface of the light-emitting element and the transparent cover or reaction hole surface of the detection plate. When the light beam emitted by the light-emitting element passes through the surface with contaminants, unexpected refraction, scattering, and diffraction phenomena occur, leading to a decrease in beam transmittance, optical path deviation, or increased background noise. This directly interferes with the accuracy and signal-to-noise ratio of information acquisition, potentially causing misjudgment of microbial growth or decreased sensitivity, ultimately affecting the reliability of drug sensitivity test results. Summary of the Invention

[0005] The purpose of this invention is to address the shortcomings of existing technologies by providing a fully automated rapid microbial identification and drug sensitivity analysis device and method, thereby solving the technical problem of decreased detection accuracy in existing optical detection systems due to internal environmental contamination.

[0006] The objective of this invention can be achieved through the following technical solutions:

[0007] A fully automated rapid microbial identification and antimicrobial susceptibility testing device includes a detection card, a housing, a turntable, a support, a mounting base, a vertical plate, a light-emitting plate, a collection mechanism, a heating mechanism, and a driving component. The device also includes:

[0008] The cleaning components are installed between the upright plate and the mounting base, and between the acquisition mechanism and the mounting base. The cleaning components are used to clean the surface of the light-emitting plate and the front and back sides of the detection card.

[0009] An air storage box is installed inside the box. The air storage box is connected to the cleaning component and provides a cleaning power source for the cleaning component.

[0010] A guide frame is provided. A second driving component is installed on the upright plate. A guide frame is installed on the output end of the second driving component. The guide frame is connected to the cleaning assembly between the upright plate and the mounting base. The guide frame drives the cleaning assembly between the upright plate and the mounting base to move up and down. The cleaning assembly between the collection mechanism and the mounting base is driven up and down by the first driving component and the collection mechanism.

[0011] As a preferred embodiment of the above technical solution, the cleaning component includes:

[0012] The protective cylinder on the cleaning assembly between the upright plate and the mounting base is fixed to the guide frame. The protective cylinder on the cleaning assembly between the acquisition mechanism and the mounting base is installed on the acquisition mechanism. The protective cylinder forms a light guide channel between the light-emitting plate and the detection card, and between the acquisition mechanism and the mounting base.

[0013] A cleaning box is installed at the bottom of the protective cylinder. One side of the cleaning box is open, and the open end of the cleaning box faces the surface of the light-emitting plate or the detection card.

[0014] An air intake pipe is installed at the bottom of the cleaning box and is connected to the air storage box;

[0015] The jet pipe is fixed to the side of the air inlet pipe and is obliquely upward, facing the surface of the light-emitting plate or the detection card.

[0016] As a preferred embodiment of the above technical solution, an air suction box is provided at the bottom of the cleaning box, a one-way valve is installed between the air suction box and the cleaning box, a one-way valve is installed on the side of the air suction box, an air suction hood is installed at one end of the one-way valve inside the cleaning box, a piston plate is movably installed inside the air suction box, an elastic element is connected between the piston plate and the bottom of the inner cavity of the air suction box, an air inlet pipe is installed at the bottom of the air suction box, a turbine is rotatably installed inside the air inlet pipe, a winding roller is provided on the shaft of the turbine, a connecting rope is wound on the winding roller, and one end of the connecting rope passes through the air suction box and connects to the piston plate.

[0017] As a preferred embodiment of the above technical solution, the cleaning box is provided with a collection groove, which is located between the jet pipe and the suction hood, and a filter screen is installed at an angle inside the collection groove.

[0018] As a preferred embodiment of the above technical solution, the cleaning box has a wiping plate on the side facing the surface of the light-emitting plate or the detection card.

[0019] As a preferred embodiment of the above technical solution, a movable plate is movably installed inside the gas storage box, a drive frame is provided on the guide frame, the drive frame is sleeved on the outside of the gas storage box, the drive frame drives the movable plate to move up and down, a one-way valve four is installed on the gas storage box, the one-way valve four is connected to several air inlet pipes, a U-shaped pipe is provided at the bottom of the gas storage box, water is stored at the bend of the U-shaped pipe, and a one-way valve three is installed at the other end of the U-shaped pipe.

[0020] As a preferred embodiment of the above technical solution, the acquisition mechanism is provided with a telescopic cover on the side facing the mounting base, and the protective cylinder is installed inside the telescopic cover.

[0021] An analytical method for a fully automated rapid microbial identification and antimicrobial susceptibility testing device, the method being applied to the aforementioned fully automated rapid microbial identification and antimicrobial susceptibility testing device, the method comprising the following steps:

[0022] Step S1: Rotate the turntable to move the mounting base carrying the detection card between the upright plate and the acquisition mechanism, and keep the mounting base, upright plate and acquisition mechanism in a parallel state;

[0023] Step S2: Drive component one moves the collection mechanism downward, while drive component two moves the cleaning component downward through the guide frame. During the downward movement of the cleaning component, high-speed gas is obliquely sprayed onto the surface of the light-emitting plate or detection card through its internal jet pipe to impact and remove attached contaminants.

[0024] Step S3: While spraying gas, suction is generated by the suction hood inside the cleaning component, so that the sprayed gas and the removed contaminants form a parabolic trajectory toward the inside of the cleaning box, thereby achieving directional recovery of contaminants.

[0025] Step S4: After cleaning, move the collection mechanism to the collection position and stop moving. At this time, the light-emitting plate, protective tube, test card, and collection mechanism are in a straight line. The light-emitting plate emits light to illuminate the test card, and the collection mechanism collects the information on the test card and performs microbial identification and drug sensitivity analysis.

[0026] The beneficial effects of this invention are as follows:

[0027] 1. In this invention, several cleaning components clean the surface of the light-emitting plate and both sides of the detection card during the downward movement, removing contaminants attached to the surface of the light-emitting plate and both sides of the detection card. When the collection mechanism moves to the collection position, it stops moving. At this time, the light-emitting plate, protective cylinder, detection card, protective cylinder and collection mechanism are in a straight line. After the light-emitting plate emits light to illuminate the detection card, the collection mechanism collects and analyzes the information on the detection card. This effectively avoids contaminants affecting the reliability of the detection and analysis results, thereby improving the detection accuracy.

[0028] 2. In this invention, the high-speed gas ejected from the jet pipe impacts the contaminants attached to both sides of the light-emitting plate and the detection card. The gas is ejected at an angle, which combines the shearing force, impact force and lift of the high-speed gas, making the contaminants easy to loosen and "pry up". This allows the contaminants to be quickly separated from the light-emitting plate or the detection card, improving the cleaning effect of the contaminants. This effectively avoids the contaminants affecting the reliability of the detection and analysis results and improves the detection accuracy.

[0029] 3. In this invention, the gas is made to move in a parabolic motion by the combination of the jet pipe and the suction hood. This causes the cleaned contaminants to move into the cleaning box, which on the one hand prevents the contaminants from re-adhering to the surface of the light-emitting plate and the detection card, and on the other hand, concentrates the contaminants to further reduce the amount of contaminants in the box, thereby reducing the risk of contaminants adhering to the surface of the light-emitting plate and the detection card. This further effectively avoids the contaminants from affecting the reliability of the detection and analysis results and further improves the detection accuracy. Attached Figure Description

[0030] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0031] Figure 2 This is a partial structural diagram of the present invention;

[0032] Figure 3 This is a schematic diagram of the structure of the present invention from another perspective;

[0033] Figure 4 A schematic diagram of the component structure for cleaning;

[0034] Figure 5 A schematic diagram of the overall structure of the cleanup components;

[0035] Figure 6 This is a schematic diagram of the cross-sectional structure of the gas storage box.

[0036] In the picture:

[0037] 1. Detection card; 2. Box body; 3. Turntable; 4. Bracket; 41. Mounting base; 5. Vertical plate; 51. Light-emitting plate; 6. Collection mechanism; 61. Telescopic cover; 7. Cleaning assembly; 71. Protective cylinder; 72. Cleaning box; 721. Collection trough; 722. Filter screen; 73. Air inlet pipe; 74. Air jet pipe; 75. Suction box; 751. One-way valve one; 752. One-way valve two; 76. Suction cover; 77. Piston plate; 771. Elastic element; 772. Connecting rope; 78. Turbine; 781. Rewinding roller; 79. Wiping plate; 8. Air storage box; 81. U-shaped tube; 82. Movable plate; 83. One-way valve three; 84. One-way valve four; 9. Guide frame; 91. Drive frame; 10. Heating mechanism; 11. Drive component one; 12. Drive component two. Detailed Implementation

[0038] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0039] like Figures 1-6 As shown, a fully automated rapid microbial identification and antimicrobial susceptibility testing device includes a detection card 1, a housing 2, a turntable 3, a support 4, a mounting base 41, a vertical plate 5, a light-emitting plate 51, a collection mechanism 6, a heating mechanism 10, and a driving component 11. The device also includes:

[0040] Several sets of cleaning components 7 are installed between the upright plate 5 and the mounting base 41, and between the acquisition mechanism 6 and the mounting base 41. The cleaning components 7 are used to clean the surface of the light-emitting plate 51 and the front and back sides of the detection card 1.

[0041] An air storage box 8 is installed inside the housing 2. The air storage box 8 is connected to the cleaning component 7 and provides a cleaning power source for the cleaning component 7.

[0042] The guide frame 9 is mounted on the upright plate 5. The second driving component 12 is mounted on the output end of the second driving component 12. The guide frame 9 is connected to the cleaning component 7 between the upright plate 5 and the mounting base 41. The guide frame 9 drives the cleaning component 7 between the upright plate 5 and the mounting base 41 to move up and down. The cleaning component 7 between the collection mechanism 6 and the mounting base 41 is driven up and down by the first driving component 11 and the collection mechanism 6.

[0043] In practical application, before the acquisition mechanism 6 acquires information from the detection card 1, the turntable 3 rotates, causing the mounting base 41 on one side of the bracket 4 to rotate between the upright plate 5 and the acquisition mechanism 6. The mounting base 41, the upright plate 5, and the acquisition mechanism 6 remain parallel. At this time, the first driving component 11 drives the acquisition mechanism 6 to move downward, and the second driving component 12 drives several cleaning components 7 to move downward through the guide frame 9. During the downward movement, the cleaning components 7 clean the surface of the light-emitting plate 51 and both sides of the detection card 1, removing the contaminants attached to the surface of the light-emitting plate 51 and both sides of the detection card 1. When the acquisition mechanism 6 moves to the acquisition position, it stops moving. At this time, the light-emitting plate 51, the protective cylinder 71, the detection card 1, the protective cylinder 71, and the acquisition mechanism 6 are in a straight line. After the light-emitting plate 51 illuminates the detection card 1, the acquisition mechanism 6 acquires and analyzes the information on the detection card 1. This effectively avoids contaminants affecting the reliability of the detection and analysis results, thereby improving the detection accuracy.

[0044] The protective cylinder 71 can block external contaminants when collecting information, thereby effectively preventing contaminants from affecting the reliability of the detection and analysis results and further improving the detection accuracy. The protective cylinder 71 can also ensure the brightness and uniformity of the light beam emitted by the light-emitting plate 51, further improving the detection accuracy.

[0045] Furthermore, cleanup component 7 includes:

[0046] The protective cylinder 71 on the cleaning assembly 7 between the upright plate 5 and the mounting base 41 is fixed to the guide frame 9. The protective cylinder 71 on the cleaning assembly 7 between the acquisition mechanism 6 and the mounting base 41 is installed on the acquisition mechanism 6. The protective cylinder 71 forms a light guiding channel between the light-emitting plate 51 and the detection card 1, and between the acquisition mechanism 6 and the mounting base 41.

[0047] Cleaning box 72 is installed at the bottom of protective cylinder 71. One side of cleaning box 72 is open and the open end of cleaning box 72 faces the surface of light-emitting plate 51 or detection card 1.

[0048] The air intake pipe 73 is installed at the bottom of the cleaning box 72 and is connected to the air storage box 8.

[0049] The jet pipe 74 is fixed to the side of the air inlet pipe 73. The jet pipe 74 is set obliquely upward and faces the surface of the light-emitting plate 51 or the detection card 1.

[0050] The acquisition mechanism 6 has a telescopic cover 61 on the side facing the mounting base 41, and the protective cylinder 71 is installed inside the telescopic cover 61.

[0051] A movable plate 82 is movably installed inside the gas storage box 8. A drive frame 91 is provided on the guide frame 9. The drive frame 91 is fitted outside the gas storage box 8. The drive frame 91 drives the movable plate 82 to move up and down. A one-way valve 84 is installed on the gas storage box 8. The one-way valve 84 is connected to several air inlet pipes 73. A U-shaped pipe 81 is provided at the bottom of the gas storage box 8. Water is stored at the bend of the U-shaped pipe 81. A one-way valve 83 is installed at the other end of the U-shaped pipe 81.

[0052] In one embodiment, the telescopic cover 61 can move horizontally in conjunction with the acquisition mechanism 6 to ensure that the cleaning component 7 can operate normally when the acquisition mechanism 6 is close to the detection card 1 to collect information; the drive frame 91 can be made of electromagnetic material, and the movable plate 82 can be made of magnetic material. After the drive frame 91 is powered on, it attracts the movable plate 82, thereby driving the movable plate 82 to move.

[0053] In practical application, the guide frame 9 moves downward, driving the protective cylinder 71 downward. Simultaneously, the drive frame 91 drives the movable plate 82 downward. When the movable plate 82 moves downward, it squeezes the gas in the gas storage box 8, causing the gas in the gas storage box 8 to enter the air inlet pipe 73 through the one-way valve 84. Finally, it is ejected at high speed from the jet pipe 74. The high-speed ejected gas impacts the contaminants attached to both sides of the light-emitting plate 51 and the detection card 1. The gas is ejected at an angle, which combines the shearing force, impact force, and lift of the high-speed gas, making it easy to loosen and "pry up" the contaminants. This allows the contaminants to be quickly separated from the light-emitting plate 51 or the detection card 1, improving the cleaning effect of the contaminants. This effectively avoids the contaminants affecting the reliability of the detection and analysis results and improves the detection accuracy.

[0054] After information collection is completed, the drive frame 91 will move the movable plate 82 upward, creating a suction action inside the gas storage box 8. This causes the gas in the chamber 2 to enter the U-shaped tube 81 through the one-way valve 83. The gas will pass through the water in the form of bubbles. During this process, the water and gas come into contact. On the one hand, the gas contains moisture after contacting the water. When the gas enters the gas storage box 8 and is ejected from the jet pipe 74, the high-speed gas ejected contains water mist. This water mist can wash the surface of the light-emitting plate 51 and the detection card 1, thereby further improving the cleaning effect of pollutants. At the same time, it can also suppress dust and effectively prevent pollutants from adhering to the light-emitting plate 51 again. The density of the water mist sprayed simultaneously from the surface of the light-emitting plate 51 and the surface of the detection card 1 is greater than that of the gas. When the high-speed water droplets collide directly with the pollutants, they will transfer much greater momentum than pure airflow. This microscopic and dense impact can effectively "knock" the pollutants off, thereby further improving the cleaning effect of the pollutants. On the other hand, after the gas comes into contact with the water, the pollutants in the gas will be filtered out and these pollutants will remain in the water, thereby reducing the amount of pollutants in the chamber 2, thereby reducing the risk of pollutants adhering to the surface of the light-emitting plate 51 and the surface of the detection card 1, thereby further effectively avoiding the impact of pollutants on the reliability of the detection and analysis results, and further improving the detection accuracy.

[0055] Furthermore, a suction box 75 is provided at the bottom of the cleaning box 72. A one-way valve 751 is installed between the suction box 75 and the cleaning box 72. A one-way valve 752 is installed on the side of the suction box 75. A suction hood 76 is installed at one end of the one-way valve 751 located inside the cleaning box 72. A piston plate 77 is movably installed inside the suction box 75. An elastic element 771 is connected between the piston plate 77 and the bottom of the inner cavity of the suction box 75. An air inlet pipe 73 is installed at the bottom of the suction box 75. A turbine 78 is rotatably installed inside the air inlet pipe 73. A winding roller 781 is provided on the shaft of the turbine 78. A connecting rope 772 is wound on the winding roller 781. One end of the connecting rope 772 passes through the suction box 75 and connects to the piston plate 77.

[0056] In practical application, when the gas passes through the inlet pipe 73, it drives the turbine 78 to rotate. The turbine 78 drives the take-up roller 781 to rotate, causing the take-up roller 781 to take up the connecting rope 772. As a result, the piston plate 77 gradually moves downward. During the downward movement of the piston plate 77, the pressure inside the suction box 75 gradually decreases, thereby causing the suction hood 76 to draw external gas into the suction box 75 to maintain the pressure balance inside the suction box 75. In conjunction with the jet pipe 74 ejecting high-speed gas, the high-speed gas is absorbed by the suction hood 76 after being ejected, causing the gas to exhibit a parabolic motion. This causes the cleaned contaminants to move into the cleaning box 72, preventing contaminants from re-adhering to the surface of the light-emitting plate 51 and the detection card 1. On the other hand, it concentrates and collects contaminants, further reducing the amount of contaminants in the box 2, thereby reducing the risk of contaminants adhering to the surface of the light-emitting plate 51 and the detection card 1. This further effectively avoids contaminants affecting the reliability of the detection and analysis results, and further improves the detection accuracy.

[0057] When the collecting mechanism 6 is collecting information, the cleaning box 72 is in a stationary state. Through the rebound capability of the elastic element 771, the piston plate 77 discharges the gas above it through the one-way valve 752. The piston plate 77 gradually returns to its original position, so that the next high-speed gas ejection can guide the contaminants into the cleaning box 72 in a parabolic state.

[0058] Furthermore, a collection slot 721 is provided on the cleaning box 72. The collection slot 721 is located between the jet pipe 74 and the suction hood 76. A filter screen 722 is installed at an angle inside the collection slot 721.

[0059] In practical application, the contaminants entering the cleaning box 72 will come into contact with the filter screen 722. Through the inclined guidance of the filter screen 722, the contaminants will gradually enter the collection tank 721, preventing the contaminants from re-adhering to the surface of the light-emitting plate 51 and the detection card 1. At the same time, the amount of contaminants in the box 2 will be reduced, and the risk of contaminants adhering to the surface of the light-emitting plate 51 and the detection card 1 will be reduced.

[0060] Furthermore, a wiping plate 79 is provided on the side of the cleaning box 72 facing the surface of the light-emitting plate 51 or the detection card 1.

[0061] In practical application, after the contaminants on the light-emitting plate 51 and the detection card 1 are cleaned, the wiping plate 79 moves to the cleaned area and wipes the surface of the light-emitting plate 51 and the detection card 1, thereby further improving the cleanliness of the surface of the light-emitting plate 51 and the detection card 1, thus effectively avoiding the impact of contaminants on the reliability of the detection and analysis results, and thus improving the detection accuracy.

[0062] An analytical method for a fully automated rapid microbial identification and antimicrobial susceptibility testing device, the method being applied to the aforementioned fully automated rapid microbial identification and antimicrobial susceptibility testing device, the method comprising the following steps:

[0063] Step S1: Rotate the turntable 3 to rotate the mounting base 41 carrying the detection card 1 between the upright plate 5 and the acquisition mechanism 6, and keep the mounting base 41, the upright plate 5 and the acquisition mechanism 6 in a parallel state.

[0064] Step S2: Drive component 11 drives the collection mechanism 6 to move down, while drive component 2 12 drives the cleaning component 7 to move down through the guide frame 9. During the downward movement of the cleaning component 7, high-speed gas is obliquely sprayed onto the surface of the light-emitting plate 51 or the detection card 1 through the jet pipe 74 inside it to impact and remove the attached contaminants.

[0065] Step S3: While the gas is being sprayed, suction is generated by the suction hood 76 inside the cleaning component 7, causing the sprayed gas and the removed contaminants to form a parabolic trajectory toward the inside of the cleaning box 72, so as to achieve directional recovery of contaminants.

[0066] Step S4: After cleaning is completed, move the collection mechanism 6 to the collection position and stop moving. At this time, the light-emitting plate 51, the protective cylinder 71, the detection card 1, the protective cylinder 71 and the collection mechanism 6 are in a straight line. The light-emitting plate 51 emits light to illuminate the detection card 1. The collection mechanism 6 collects the information on the detection card 1 and performs microbial identification and drug sensitivity analysis.

[0067] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed invention.

Claims

1. A fully automated rapid microbial identification and drug sensitivity analysis device, comprising a detection card (1), a box (2), a turntable (3), a bracket (4), a mounting base (41), a vertical plate (5), a light-emitting plate (51), a collection mechanism (6), a heating mechanism (10), and a driving component (11), characterized in that, The device further includes: Cleaning components (7): Several sets of cleaning components (7) are installed between the upright plate (5) and the mounting base (41) and between the acquisition mechanism (6) and the mounting base (41). The cleaning components (7) are used to clean the surface of the light-emitting plate (51) and the front and back sides of the detection card (1). An air storage box (8) is installed inside the housing (2). The air storage box (8) is connected to the cleaning component (7). The air storage box (8) provides a cleaning power source for the cleaning component (7). The guide frame (9) is installed on the upright plate (5) and the drive component (12) is installed on the output end of the drive component (12). The guide frame (9) is connected to the cleaning component (7) between the upright plate (5) and the mounting base (41). The guide frame (9) drives the cleaning component (7) between the upright plate (5) and the mounting base (41) to move up and down. The cleaning component (7) between the collection mechanism (6) and the mounting base (41) is driven up and down by the drive component (11) and the collection mechanism (6).

2. The fully automated rapid microbial identification and antimicrobial susceptibility testing device according to claim 1, characterized in that, The cleaning component (7) includes: The protective cylinder (71) on the cleaning assembly (7) between the upright plate (5) and the mounting base (41) is fixed on the guide frame (9). The protective cylinder (71) on the cleaning assembly (7) between the acquisition mechanism (6) and the mounting base (41) is installed on the acquisition mechanism (6). The protective cylinder (71) forms a light guide channel between the light-emitting plate (51) and the detection card (1), and between the acquisition mechanism (6) and the mounting base (41). Cleaning box (72), the bottom of the protective cylinder (71) is equipped with a cleaning box (82), one side of the cleaning box (82) is open, and the open end of the cleaning box (82) faces the surface of the light-emitting plate (51) or the detection card (1); An air inlet pipe (73) is installed at the bottom of the cleaning box (72), and the air inlet pipe (73) is connected to the air storage box (8); The jet pipe (74) is fixed to the side of the air intake pipe (73), and the jet pipe (74) is set obliquely upward, facing the surface of the light-emitting plate (51) or the detection card (1).

3. The fully automated rapid microbial identification and antimicrobial susceptibility testing device according to claim 2, characterized in that, The bottom of the cleaning box (72) is provided with an air intake box (75). A one-way valve (751) is installed between the air intake box (75) and the cleaning box (72). A one-way valve (752) is installed on the side of the air intake box (75). An air intake cover (76) is installed at one end of the one-way valve (751) inside the cleaning box (72). A piston plate (77) is movably installed inside the air intake box (75). An elastic element (771) is connected between the piston plate (77) and the bottom of the inner cavity of the air intake box (75). The air inlet pipe (73) is installed at the bottom of the air intake box (75). A turbine (78) is rotatably installed inside the air inlet pipe (73). A winding roller (781) is provided on the shaft of the turbine (78). A connecting rope (772) is wound on the winding roller (781). One end of the connecting rope (772) passes through the air intake box (75) and connects to the piston plate (77).

4. The fully automated rapid microbial identification and antimicrobial susceptibility testing device according to claim 3, characterized in that, The cleaning box (72) is provided with a collection groove (721), which is located between the jet pipe (74) and the air intake hood (76). A filter screen (722) is installed obliquely inside the collection groove (721).

5. The fully automated rapid microbial identification and antimicrobial susceptibility testing device according to claim 2, characterized in that, The cleaning box (72) has a wiping plate (79) on the side facing the surface of the light-emitting plate (51) or the detection card (1).

6. The fully automated rapid microbial identification and antimicrobial susceptibility testing device according to claim 4, characterized in that, A movable plate (82) is movably installed inside the gas storage box (8). A drive frame (91) is provided on the guide frame (9). The drive frame (91) is fitted outside the gas storage box (8). The drive frame (91) drives the movable plate (82) to move up and down. A one-way valve four (84) is installed on the gas storage box (8). The one-way valve four (84) is connected to several air inlet pipes (73). A U-shaped pipe (81) is provided at the bottom of the gas storage box (8). Water is stored at the bend of the U-shaped pipe (81). A one-way valve three (83) is installed at the other end of the U-shaped pipe (81).

7. The fully automated rapid microbial identification and antimicrobial susceptibility testing device according to claim 2, characterized in that, The acquisition mechanism (6) has a telescopic cover (61) on the side facing the mounting base (41), and the protective cylinder (71) is installed inside the telescopic cover (61).

8. An analytical method for a fully automated rapid microbial identification and antimicrobial susceptibility testing device, characterized in that, The method is applied to the fully automated rapid microbial identification and antimicrobial susceptibility testing device as described in any one of claims 1-7 above, and the method includes the following steps: Step S1: Rotate the turntable (3) to rotate the mounting base (41) carrying the detection card (1) between the upright plate (5) and the acquisition mechanism (6), and keep the mounting base (41), the upright plate (5) and the acquisition mechanism (6) in a parallel state; Step S2: Drive component one (11) drives the collection mechanism (6) to move down, while drive component two (12) drives the cleaning component (7) to move down through the guide frame (9). During the downward movement of the cleaning component (7), high-speed gas is obliquely sprayed onto the surface of the light-emitting plate (51) or the detection card (1) through the jet pipe (74) inside it to impact and remove the attached pollutants. Step S3: While the gas is being sprayed, suction is generated by the suction hood (76) inside the cleaning component (7), so that the sprayed gas and the pollutants being removed form a parabolic trajectory toward the inside of the cleaning box (72) to achieve directional recycling of pollutants; Step S4: After cleaning, move the collection mechanism (6) to the collection position and stop moving. At this time, the light-emitting plate (51), the protective tube (71), the test card (1), the protective tube (71) and the collection mechanism (6) are in a straight line. The light-emitting plate (51) emits light to illuminate the test card (1). The collection mechanism (6) collects the information on the test card (1) and performs microbial identification and drug sensitivity analysis.

Citation Information

Patent Citations

  • Microbial Antimicrobial Susceptibility Analyzer

    CN114107039B