A medicine micro-particle tabletting forming press and a tablet manufacturing process thereof

Abstract

The application provides a medicine particle tabletting forming press and a tabletting manufacturing process thereof, and relates to the technical field of tabletting presses, which comprises a forming mounting portion, an extrusion device is mounted in the forming mounting portion; a rotary forming piece is mounted on the extrusion device; the rotary forming piece is used for extrusion forming medicine particles; a filling device is mounted on the forming mounting portion; a finishing piece is mounted on the forming mounting portion; the rotary forming piece cooperates with the extrusion device, so that when the medicine particles are extrusion formed, the adhesion rate of the end of the tabletting shaft is reduced through the rotatable tabletting shaft, and the smoothness of the tablet surface is improved through the auxiliary friction of the rotatable tabletting shaft; and the problems that the current medicine particle tabletting forming press is inconvenient to rotate and prevent adhesion, and is inconvenient to surround the tablet for protection and cleaning during extrusion forming are solved.

Description

Technical Field

[0001] This invention relates to the field of tablet pressing technology, and in particular to a tablet compression press for pharmaceutical microparticles and its tablet manufacturing process. Background Technology

[0002] In actual tablet manufacturing, the pre-processed drug microparticles need to be extruded and formed into tablets by a press to facilitate swallowing. In the tablet compression forming process, factors such as the precision of the press directly affect the forming quality. Traditional presses are widely used due to their advantages such as high efficiency in extrusion forming. Current drug microparticle tableting presses usually extrude tablets vertically, which can easily cause drug powder to adhere to the punch head, making it difficult to rotate and prevent sticking. At the same time, the smoothness of the formed tablet is also not good. In order to ensure smooth insertion into the forming hole and prevent jamming, traditional punch heads are usually reduced in diameter with a certain gap. Coupled with long-term wear, this usually results in a raised burr around the edge of the formed tablet. Direct brushing can easily cause the drug to break, increasing manufacturing costs and making it difficult to surround and clean the tablet during extrusion forming. Summary of the Invention

[0003] This disclosure relates to a pharmaceutical microparticle tableting press and its tableting manufacturing process, in order to solve the problems of current pharmaceutical microparticle tableting presses being inconvenient for rotation and anti-sticking, and inconvenient for surrounding and cleaning the tablets during extrusion molding.

[0004] In a first aspect, this disclosure provides a pharmaceutical microparticle tableting press, specifically comprising a molding mounting section, wherein an extrusion device is installed inside the molding mounting section; a rotary forming component is mounted on the extrusion device; the rotary forming component is used to extrude and form pharmaceutical microparticles; a filling device is mounted on the molding mounting section; a trimming component is mounted on the molding mounting section; the trimming component is used to trim tablets; a driving device is mounted on the molding mounting section; the driving device is used to control the movement of the trimming component; the molding mounting section includes: a housing, a discharge port, and a mounting plate, wherein the discharge port is fixedly mounted on the side of the housing and is inclined; and the mounting plate is fixedly mounted inside the housing.

[0005] In at least some embodiments, the molding mounting part further includes: an inclined discharge trough, a dosing hopper, and a vibration motor; the inclined discharge trough is formed on the mounting plate; the dosing hopper is fixedly mounted on the housing; the inclined discharge trough is connected to the discharge port; the vibration motor is fixedly mounted on the bottom of the mounting plate by a bracket; and two rows of molding through holes are formed on the mounting plate.

[0006] In at least some embodiments, the extrusion device includes: an extrusion mounting frame, a tableting hydraulic cylinder, a push plate, a drive rack, and a reciprocating electric push rod. Two extrusion mounting frames are provided, and the two frames have identical structures. The two extrusion mounting frames are respectively fixedly mounted on the upper and lower sides of the mounting plate by bolts. Two tableting hydraulic cylinders are fixedly mounted on the extrusion mounting frame, and a push plate is fixedly mounted on the output of each of the two cylinders, with the push plate slidably fitting against the inner side of the extrusion mounting frame. Two drive racks are slidably mounted on the push plate, and a reciprocating electric push rod is fixedly mounted on each of the two drive racks. The output shafts of the two reciprocating electric push rods are respectively fixedly mounted on the push plate.

[0007] In at least some embodiments, the rotary forming component includes: a pressing shaft and a drive gear; two rows of pressing shafts are rotatably mounted on the two push plates respectively, and the length of the upper two rows of pressing shafts is less than that of the lower two rows of pressing shafts; a drive gear is fixedly mounted at the end of the pressing shaft and the drive gear is attached to the push plate; the drive rack meshes with the drive gear on the same side; and the lower row of pressing shafts is inserted into two rows of forming through holes opened on the mounting plate.

[0008] In at least some embodiments, the filling device includes: a filling frame and a filling electric push rod, wherein the filling frame is provided with sliding grooves on both sides; the filling frame is slidably attached to the surface of the mounting plate; the filling electric push rod is fixedly mounted on the mounting plate, and the output shaft of the filling electric push rod is fixedly mounted on the filling frame; the filling frame is located below the dosing hopper.

[0009] In at least some embodiments, the filling device further includes: a pusher plate and guide holes, wherein the pusher plate is fixedly installed on the side of the filling frame; the pusher plate is slidably installed on the mounting plate; the pusher plate has two rows of guide holes, and the two rows of guide holes correspond to two rows of forming through holes opened on the mounting plate; the tops of the two rows of guide holes are chamfered.

[0010] In at least some embodiments, the trimming component includes: a trimming brush holder, a sliding shaft seat, and rubber blocks. The trimming brush holder is slidably mounted on a mounting plate. The sliding shaft seat is fixedly mounted on the mounting plate. The sliding shaft seat has a through hole. A row of rubber blocks is fixedly mounted on the trimming brush holder, and each row of rubber blocks corresponds to a guide hole.

[0011] In at least some embodiments, the trimming component further includes: bristles and a spring shaft, with bristles respectively provided on the upper and lower sides inside the trimming brush holder; the spring shaft is fixedly installed on the trimming brush holder; the spring shaft is slidably inserted into the slide shaft seat; and a spring is sleeved on the spring shaft.

[0012] In at least some embodiments, the driving device includes: a drive motor and a cam, the drive motor being fixedly mounted on a mounting plate and the output shaft of the drive motor passing through the mounting plate; a cam is fixedly mounted on the output shaft of the drive motor and the cam is attached to the side of the trimming brush holder.

[0013] A pharmaceutical microparticle tablet manufacturing process:

[0014] 1) The tableting shaft is driven to move down by the two upper tableting hydraulic cylinders, and after being inserted into the guide hole, it is inserted into the two rows of forming through holes on the mounting plate to compress and form tablets;

[0015] 2) The four reciprocating electric push rods drive the four drive racks to move back and forth, and the meshing drive gears drive the pressure shaft to rotate to prevent sticking.

[0016] This invention provides a pharmaceutical microparticle tableting press and its tablet manufacturing process, which has the following beneficial effects:

[0017] This invention employs a rotational forming component in conjunction with an extrusion device. During the extrusion forming of pharmaceutical microparticles, the rotatable tableting shaft reduces the adhesion rate at the end of the tableting shaft, thereby reducing economic losses and cleaning costs. In particular, for some tablets with lower compression pressure, powder is easily adhering to the end of the tableting shaft. With this structure, the tableting shaft can rotate continuously, reducing the adhesion rate. At the same time, the rotatable tableting shaft can improve the smoothness of the tablet surface through auxiliary friction.

[0018] In addition, the filling device can facilitate the rapid filling of drug microparticles into the two rows of formed through holes on the mounting plate, which is convenient for subsequent extrusion. At the same time, the chamfered top of the guide hole can guide the tableting shaft above, making it easier for the tableting shaft to insert into the two rows of formed through holes on the mounting plate, reducing the jamming damage rate, and also preventing drug microparticle powder from remaining at the chamfered top of the guide hole.

[0019] In addition, the drive device can drive the trimming part to move back and forth. With the help of the brush bristles, the edges of the tablet can be cleaned as it is pushed forward by the tablet pusher plate. This makes the tablet more aesthetically pleasing and easier to swallow, reducing discomfort caused by the sharp edges. At the same time, the structure uses the tablet pusher plate to push the tablet, which can protect the tablet from excessive brushing and even cause the tablet to break. Attached Figure Description

[0020] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings of the embodiments will be briefly described below.

[0021] The accompanying drawings described below are only related to some embodiments of the invention and are not intended to limit the invention.

[0022] In the attached diagram:

[0023] Figure 1 A schematic diagram of the overall structure of a pharmaceutical microparticle tableting press according to this application is shown;

[0024] Figure 2 A schematic diagram of the internal structure of a pharmaceutical microparticle tableting press according to this application is shown;

[0025] Figure 3 A schematic diagram showing the location of the inclined discharge trough in this application is shown;

[0026] Figure 4 A cross-sectional view of the internal structure of a pharmaceutical microparticle tableting press according to this application is shown;

[0027] Figure 5 A schematic diagram of the overall structure of the extrusion device of this application is shown;

[0028] Figure 6 A schematic diagram of the overall structure of the rotationally formed part of this application is shown;

[0029] Figure 7 A schematic diagram of the overall structure of the filling device of this application is shown;

[0030] Figure 8 A schematic diagram showing the location of the guide hole in this application is shown;

[0031] Figure 9 A schematic diagram of the overall structure of the trimming part of this application is shown;

[0032] Figure 10 A schematic diagram of the tablet press shaft mounting position is shown in this application.

[0033] List of reference numerals

[0034] 1. Molding and mounting section; 101. Housing; 1011. Discharge port; 102. Mounting plate; 1021. Inclined discharge trough; 103. Dosing hopper; 104. Vibration motor; 2. Extrusion device; 201. Extrusion mounting frame; 202. Tableting hydraulic cylinder; 203. Push plate; 204. Drive rack; 205. Reciprocating electric push rod; 3. Rotational molding part; 301. Tableting shaft; 302. Drive gear; 4. Filling device; 401. Filling frame; 402. Filling electric push rod; 403. Push plate; 4031. Guide hole; 5. Trimming part; 501. Trimming brush holder; 5011. Sliding shaft seat; 5012. Rubber block; 502. Brush bristles; 503. Spring shaft; 6. Drive device; 601. Drive motor; 602. Cam. Detailed Implementation

[0035] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the described embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0036] Example 1: Please refer to Figures 1 to 10 :

[0037] This invention proposes a pharmaceutical microparticle tableting press, comprising a molding mounting part 1, an extrusion device 2 installed inside the molding mounting part 1; a rotary forming component 3 installed on the extrusion device 2; the rotary forming component 3 is used to extrude and form pharmaceutical microparticles; a filling device 4 is installed on the molding mounting part 1; a trimming component 5 is installed on the molding mounting part 1; the trimming component 5 is used to trim the tablets; a driving device 6 is installed on the molding mounting part 1; the driving device 6 is used to control the movement of the trimming component 5; the molding mounting part 1 includes: a housing 101, a discharge port 1011 and a mounting plate 102, the discharge port 1011 is fixedly installed on the side of the housing 101 and the discharge port 1011 is inclined; the mounting plate 102 is fixedly installed inside the housing 101.

[0038] In this embodiment, the molding mounting part 1 further includes: an inclined discharge trough 1021, a dosing hopper 103, and a vibration motor 104. The inclined discharge trough 1021 is formed on the mounting plate 102; the dosing hopper 103 is fixedly mounted on the housing 101; the inclined discharge trough 1021 is connected to the discharge port 1011; the vibration motor 104 is fixedly mounted on the bottom of the mounting plate 102 by a bracket; two rows of molding through holes are formed on the mounting plate 102; the extrusion device 2 includes: an extrusion mounting frame 201, a tableting hydraulic cylinder 202, a push plate 203, a drive rack 204, and a reciprocating electric push rod 205. Two extrusion mounting frames 201 are provided, and two extrusion... The structures on the mounting bracket 201 are identical; the two extrusion mounting brackets 201 are respectively fixedly mounted on the upper and lower sides of the mounting plate 102 by bolts; two pressing hydraulic cylinders 202 are fixedly mounted on the extrusion mounting bracket 201, and a push plate 203 is fixedly mounted on the output of the two pressing hydraulic cylinders 202, and the push plate 203 slides against the inner side of the extrusion mounting bracket 201; two drive racks 204 are slidably mounted on the push plate 203, and reciprocating electric push rods 205 are fixedly mounted on the two drive racks 204 respectively; the output shafts of the two reciprocating electric push rods 205 are respectively fixedly mounted on the push plate 203; the rotary forming part 3 includes: a pressing plate The device comprises a shaft 301 and a drive gear 302. Two rows of tableting shafts 301 are rotatably mounted on two push plates 203, with the upper two rows of tableting shafts 301 being shorter than the lower two rows. A drive gear 302 is fixedly mounted at the end of each tableting shaft 301 and is attached to the push plate 203. A drive rack 204 meshes with the drive gear 302 on the same side. The lower row of tableting shafts 301 is inserted into two rows of forming through holes on the mounting plate 102. By using a rotary forming component 3 in conjunction with the extrusion device 2, the rotatable tableting shafts 301 can reduce the adhesion of the ends of the tableting shafts 301 during the extrusion forming of pharmaceutical microparticles. This structure reduces adhesion, lowers economic losses and cleaning costs, improves drug forming quality, and avoids the direct vertical downward squeezing of the tableting shaft 301. When the shaft is pressed down directly, especially for tablets with lower compression pressure, powder tends to adhere to the end of the shaft. In this structure, the tableting shaft 301 can rotate continuously, reducing adhesion. At the same time, the rotatable shaft can improve the smoothness of the tablet surface through auxiliary friction, further improving the surface quality of the formed tablet. The structure is simple to control. As the upper tableting shaft 301 is pressed down, it rotates in real time to assist in the extrusion forming of the tablet. The extrusion surface of the tableting shaft 301 is less likely to be covered with drug particles and powder.

[0039] In this embodiment, the filling device 4 includes: a filling frame 401 and a filling electric push rod 402. The filling frame 401 has sliding grooves on both sides. The filling frame 401 is slidably attached to the upper surface of the mounting plate 102. The filling electric push rod 402 is fixedly mounted on the mounting plate 102, and the output shaft of the filling electric push rod 402 is fixedly mounted on the filling frame 401. The filling frame 401 is located below the dosing hopper 103. The filling device 4 also includes: a push plate 403 and a guide hole 4031. The push plate 403 is fixedly mounted on the side of the filling frame 401. The pusher plate 403 is slidably mounted on the mounting plate 102. Two rows of guide holes 4031 are provided on the pusher plate 403, corresponding to two rows of forming through holes on the mounting plate 102. The diameter of the guide holes 4031 is larger than the diameter of the forming through holes on the mounting plate 102, facilitating subsequent tablet discharge. The tops of the two rows of guide holes 4031 are chamfered. The filling device 4 facilitates the rapid filling of drug particles into the two rows of forming through holes on the mounting plate 102, aiding in subsequent extrusion. Simultaneously, the chamfered tops of the guide holes 4031 guide the tablets upwards. The function of the square tablet compression shaft 301 is to facilitate its insertion into the two rows of forming through holes on the mounting plate 102, reducing the jamming damage rate. It also prevents drug particles from remaining at the chamfered top of the guide hole 4031, resulting in a more rational structure. Before tableting, drug particles are added to the filling frame 401 via the drug addition hopper 103. At this time, the vibration of the vibration motor 104 flattens the drug particles inside the filling frame 401. The filling electric push rod 402 drives the filling frame 401 to move to the two rows of forming through holes on the mounting plate 102. When the filling frame 401 is filled, the drug particles will leak into the two rows of forming through holes on the mounting plate 102. Then, the filling frame 401 is driven to reset by the electric push rod 402. During the process, the bottom edge of the filling frame 401 will scrape away the drug particles above the two rows of forming through holes on the mounting plate 102 to ensure the filling amount. At this time, the guide hole 4031 is also aligned with the forming through hole on the mounting plate 102. When tableting, the tableting shaft 301 is driven to move down by the two tableting hydraulic cylinders 202 above. The chamfer on the guide hole 4031 is used to prevent jamming and can pass through directly.

[0040] In Example 2, based on Example 1, the trimming component 5 includes: a trimming brush holder 501, a sliding shaft seat 5011, and rubber blocks 5012. The trimming brush holder 501 is slidably mounted on the mounting plate 102; the sliding shaft seat 5011 is fixedly mounted on the mounting plate 102; the sliding shaft seat 5011 has a through hole; a row of rubber blocks 5012 is fixedly mounted on the trimming brush holder 501, and each row of rubber blocks 5012 corresponds to a guide hole 4031; the trimming component 5 also includes: bristles 502. The trimming brush holder 501 has bristles 502 on its upper and lower sides, and a spring shaft 503. The spring shaft 503 is fixedly mounted on the trimming brush holder 501. The spring shaft 503 is slidably inserted into the sliding shaft seat 5011. A spring is sleeved on the spring shaft 503. The drive device 6 includes a drive motor 601 and a cam 602. The drive motor 601 is fixedly mounted on the mounting plate 102, and the output shaft of the drive motor 601 passes through the mounting plate 102. A cam 602 is fixedly installed on the upper part and is attached to the side of the trimming brush holder 501. The driving device 6 can drive the trimming part 5 to move back and forth. With the help of the brush bristles 502, it can assist in brushing and cleaning the edges when the tablet is pushed out by the tablet pusher plate 403. It can clean the burrs generated when the tablet is compressed by the tablet compression shaft 301, which can improve the tablet forming quality, make it more beautiful, and make it easier to swallow. It also reduces the discomfort caused by the burrs. At the same time, this structure uses the tablet pusher plate 403 to push the tablet, which can protect the tablet from excessive brushing by the brush bristles 502 and even cause the tablet to break. It can effectively protect and clean, and the structure is simple, avoiding additional losses. The trimming brush holder 501 moves back and forth to remove the protruding burrs when the tablet is pushed out. As the tablet pusher plate 403 continues to move forward, when the tablet passes the rubber block 5012, the elasticity of the rubber block 5012 can promote the tablet to fall into the inclined discharge groove 1021 and collect.

[0041] A pharmaceutical microparticle tablet manufacturing process:

[0042] 1) The tableting shaft 301 is driven to move down by the two upper tableting hydraulic cylinders 202, and after being inserted into the guide hole 4031, it continues to move down and is inserted into the two rows of forming through holes on the mounting plate 102 to compress and form tablets;

[0043] 2) The four reciprocating electric push rods 205 drive the four drive racks 204 to move back and forth, and mesh with the corresponding gears 302 to drive the tablet pressing shaft 301 to rotate and prevent sticking.

[0044] The working principle of this embodiment is as follows: First, before tableting, drug microparticles are added into the filling frame 401 through the drug addition hopper 103. At this time, in conjunction with the vibration of the vibration motor 104, the drug microparticles inside the filling frame 401 are flattened. The filling electric push rod 402 drives the filling frame 401 to move to the two rows of forming through holes on the mounting plate 102. At this time, the drug microparticles in the filling frame 401 will leak into the two rows of forming through holes on the mounting plate 102. Then, the electric push rod 402 drives the filling frame 401 to reset. During the process, the bottom edge of the filling frame 401 scrapes away the drug microparticles above the two rows of forming through holes on the mounting plate 102, ensuring the filling amount. At this time, the guide hole 4031 is also aligned with the forming through hole on the mounting plate 102. During tableting, the tableting shaft 301 is driven to move downward by the two upper tableting hydraulic cylinders 202. The chamfer on the guide hole 4031 is used to prevent jamming. As the upper tableting shaft 301 moves downward, it compresses the drug particles to form tablets. The pressure of the tableting shaft 301 driven by the tableting hydraulic cylinders 202 is controlled according to the needs. This controls the four reciprocating electric push rods 205 to drive the four drive racks 204 to move back and forth, meshing with the drive gears 302 to rotate. This causes the tableting shaft 301 to rotate in contact with the tablet. At the same time, the upper and lower rows of tableting shafts 301 rotate in opposite directions to maintain rotation. The rotation speed and rotation time are determined according to... To address the issue of drug particle powder adhering to the extrusion surface of the rotating tableting shaft 301, the vertical movement of the tableting shaft 301 can cause some particle powder to adhere, affecting subsequent extrusion molding. After extrusion, the upper tableting shaft 301 is moved upwards to its original position, and then the two lower tableting hydraulic cylinders 202 drive the two rows of lower tableting shafts 301 upwards to eject the tablet. At this point, the tablet will be inserted into the guide hole 4031, and the filling electric push rod 402 can drive the filling frame 401, which in turn moves the pusher plate 403 forward to push the tablet out of the guide hole 4031. When the pusher plate 403 moves forward to eject the tablet, it adopts a position that is in sync with the tablet. For tablets of the same thickness, the cam 602 is rotated by the drive motor 601. In conjunction with the spring on the spring shaft 503, the trimming brush holder 501 is squeezed to elastically fit the cam 602. At this time, the trimming brush holder 501 can move back to its original position to remove the protruding burrs when the tablet is pushed out. The back-to-original stroke of the trimming brush holder 501 is greater than the play of the tablet in the guide hole 4031, ensuring that the bristles 502 can effectively brush the edge of the tablet. As the tablet pusher plate 403 continues to move forward, when the tablet passes the rubber block 5012, the elasticity of the rubber block 5012 can promote the tablet to fall into the inclined discharge groove 1021 and collect, and then be discharged from the discharge port 1011 for collection.

[0045] The following points should be noted in this article:

[0046] 1. The accompanying drawings of the embodiments disclosed herein only relate to the structures involved in the embodiments disclosed herein; other structures can be referred to in a general design.

[0047] 2. Where there is no conflict, the embodiments of this disclosure and the features in the embodiments can be combined with each other to obtain new embodiments.

[0048] The above are merely specific embodiments of this disclosure, but the scope of protection of this disclosure is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in this disclosure should be included within the scope of protection of this disclosure. Therefore, the scope of protection of this disclosure should be determined by the scope of the claims.

Claims

1. A pharmaceutical microparticle tableting press, comprising a molding mounting part (1), wherein an extrusion device (2) is installed inside the molding mounting part (1); characterized in that: The extrusion device (2) is equipped with a rotational forming component (3); the rotational forming component (3) is used to extrude and form pharmaceutical microparticles; A filling device (4) is installed on the molding mounting part (1); A trimming part (5) is installed on the molding mounting part (1); the trimming part (5) is used to trim the tablet; a driving device (6) is installed on the molding mounting part (1); the driving device (6) is used to control the movement of the trimming part (5); The molding and mounting part (1) includes: a housing (101), a discharge port (1011) and a mounting plate (102). The discharge port (1011) is fixedly mounted on the side of the housing (101) and the discharge port (1011) is inclined. The mounting plate (102) is fixedly mounted inside the housing (101). The extrusion device (2) includes: an extrusion mounting frame (201), a tableting hydraulic cylinder (202), a push plate (203), a drive rack (204), and a reciprocating electric push rod (205). There are two extrusion mounting frames (201), and the two extrusion mounting frames (201) have the same structure. The two extrusion mounting frames (201) are respectively fixedly installed on the upper and lower sides of the mounting plate (102) by bolts. Two tableting hydraulic cylinders (202) are fixedly installed on the extrusion mounting frame (201), and a push plate (203) is fixedly installed on the output of the two tableting hydraulic cylinders (202), and the push plate (203) slides against the inner side of the extrusion mounting frame (201). Two drive racks (204) are slidably installed on the push plate (203), and a reciprocating electric push rod (205) is fixedly installed on each of the two drive racks (204). The output shafts of the two reciprocating electric push rods (205) are respectively fixedly installed on the push plate (203). The rotary forming component (3) includes: a pressing shaft (301) and a drive gear (302). Two rows of pressing shafts (301) are rotatably mounted on the two push plates (203), and the length of the upper two rows of pressing shafts (301) is less than that of the lower two rows of pressing shafts (301). The end of the pressing shaft (301) is fixedly mounted with a drive gear (302), and the drive gear (302) is attached to the push plate (203). The drive rack (204) meshes with the drive gear (302) on the same side. The lower row of pressing shafts (301) is inserted into two rows of forming through holes opened on the mounting plate (102). The filling device (4) includes a filling frame (401) and a filling electric push rod (402). The filling frame (401) is provided with sliding grooves on both sides. The filling frame (401) is slidably attached to the upper surface of the mounting plate (102). The filling electric push rod (402) is fixedly installed on the mounting plate (102), and the output shaft of the filling electric push rod (402) is fixedly installed on the filling frame (401). The filling device (4) further includes: a push plate (403) and guide holes (4031). The push plate (403) is fixedly installed on the side of the filling frame (401). The push plate (403) is slidably installed on the mounting plate (102). Two rows of guide holes (4031) are provided on the push plate (403), and the two rows of guide holes (4031) correspond to two rows of forming through holes provided on the mounting plate (102). The tops of the two rows of guide holes (4031) are chamfered.

2. The pharmaceutical microparticle tableting press according to claim 1, characterized in that, The molding and mounting part (1) further includes: an inclined discharge trough (1021), a dosing hopper (103) and a vibration motor (104). The inclined discharge trough (1021) is opened on the mounting plate (102). The dosing hopper (103) is fixedly installed on the housing (101). The inclined discharge trough (1021) is connected to the discharge port (1011). The vibration motor (104) is fixedly installed at the bottom of the mounting plate (102) by a bracket. The mounting plate (102) has two rows of molding through holes.

3. The pharmaceutical microparticle tableting press according to claim 2, characterized in that, The filling frame (401) is located below the dosing hopper (103).

4. The pharmaceutical microparticle tableting press according to claim 1, characterized in that, The trimming component (5) includes: a trimming brush holder (501), a sliding shaft seat (5011), and rubber blocks (5012). The trimming brush holder (501) is slidably mounted on the mounting plate (102). The sliding shaft seat (5011) is fixedly mounted on the mounting plate (102). The sliding shaft seat (5011) is provided with a through hole. A row of rubber blocks (5012) is fixedly mounted on the trimming brush holder (501), and the row of rubber blocks (5012) corresponds to the guide hole (4031).

5. A pharmaceutical microparticle tableting press according to claim 4, characterized in that, The trimming component (5) further includes: bristles (502) and spring shaft (503). The trimming brush holder (501) has bristles (502) on its upper and lower sides respectively. The spring shaft (503) is fixedly installed on the trimming brush holder (501). The spring shaft (503) is slidably inserted into the sliding shaft seat (5011). A spring is sleeved on the spring shaft (503).

6. A pharmaceutical microparticle tableting press according to claim 4, characterized in that, The driving device (6) includes a drive motor (601) and a cam (602). The drive motor (601) is fixedly mounted on the mounting plate (102), and the output shaft of the drive motor (601) passes through the mounting plate (102). The cam (602) is fixedly mounted on the output shaft of the drive motor (601), and the cam (602) is attached to the side of the trimming brush holder (501).

7. A pharmaceutical microparticle tablet manufacturing process, using the pharmaceutical microparticle tablet forming press according to claim 1, characterized in that, The steps include: 1) The upper tableting shaft (301) is controlled to move down by the two upper tableting hydraulic cylinders (202), and after being inserted into the guide hole (4031), it continues to move down and is inserted into the two rows of forming through holes on the mounting plate (102) to compress and form tablets; 2) The four reciprocating electric push rods (205) drive the four drive racks (204) to move back and forth, meshing with the corresponding gears (302) to drive the tablet pressing shaft (301) to rotate and prevent sticking.

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